CN110301364A - Experimental box is used in a kind of research of mouse Social behaviors - Google Patents
Experimental box is used in a kind of research of mouse Social behaviors Download PDFInfo
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- CN110301364A CN110301364A CN201910710565.1A CN201910710565A CN110301364A CN 110301364 A CN110301364 A CN 110301364A CN 201910710565 A CN201910710565 A CN 201910710565A CN 110301364 A CN110301364 A CN 110301364A
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- 230000011273 social behavior Effects 0.000 title claims abstract description 34
- 238000011160 research Methods 0.000 title claims abstract description 28
- 239000002184 metal Substances 0.000 claims abstract description 107
- 229910052751 metal Inorganic materials 0.000 claims abstract description 107
- 239000003086 colorant Substances 0.000 claims abstract description 18
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 30
- 229910052742 iron Inorganic materials 0.000 claims description 15
- 239000007787 solid Substances 0.000 claims description 9
- 238000003780 insertion Methods 0.000 claims description 7
- 230000037431 insertion Effects 0.000 claims description 7
- 238000009434 installation Methods 0.000 claims description 4
- 238000002474 experimental method Methods 0.000 abstract description 48
- 230000000694 effects Effects 0.000 abstract description 18
- 230000006399 behavior Effects 0.000 abstract description 10
- 230000007177 brain activity Effects 0.000 abstract description 6
- 241000699666 Mus <mouse, genus> Species 0.000 description 101
- 230000004888 barrier function Effects 0.000 description 42
- 238000000034 method Methods 0.000 description 14
- 230000008569 process Effects 0.000 description 13
- 238000004140 cleaning Methods 0.000 description 12
- 241000699670 Mus sp. Species 0.000 description 10
- 238000010586 diagram Methods 0.000 description 7
- 230000000903 blocking effect Effects 0.000 description 6
- 210000004556 brain Anatomy 0.000 description 6
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 6
- 239000010931 gold Substances 0.000 description 6
- 229910052737 gold Inorganic materials 0.000 description 6
- 206010028347 Muscle twitching Diseases 0.000 description 4
- 238000010171 animal model Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000013307 optical fiber Substances 0.000 description 2
- 208000020016 psychiatric disease Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000008279 neurobiological mechanism Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
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- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
A kind of mouse Social behaviors research experimental box comprising the cabinet of more lattice settings, fixed mouse metal strip cage, which is characterized in that strip notch is set below every lattice cabinet front, in strip notch setting can pull plate, be arranged different colours can pull plate；Can pull plate when being fully inserted into every lattice cabinet, can pull plate and cabinet be the mode stitched and fastened；The setting of metal strip cage is can be on pull plate；Spacing board is set between every two lattice cabinet, is arranged on spacing board and runs through notch from pull Board position to top；The intracorporal metal strip cage of two adjacent lattice casees is arranged in diagonal positions.Above scheme can guarantee according to the color setpoint color contrast of experimental mouse it is high can pull plate, guarantee the validity shot when experiment, it can guarantee the cheap property of activity of the mouse with merging structure through notch by being arranged, observe the brain activity of mouse and the relationship of corresponding behavior, it is observed and recorded at any time without experimenter, reduces experimenter's workload.
Description
Technical field
The invention belongs to mouse experiment experimental boxs, and in particular to use experimental box for a kind of research of mouse Social behaviors.
Background technique
Social activity refers to interpersonal dealings in society, the consciousness transmitting information, rapping off, to reach certain
The social activities of purpose.People only constantly associates with all kinds of personnel and information communication, can just enrich constantly oneself, send out
It opens up oneself, expand oneself.For many animals, social no less important.Social behaviors obstacle is the allusion quotation of many mental diseases
Type feature, including depression, self-closing disease, schizophrenia and obsessive-compulsive disorder etc..Therefore, the variation of Social behaviors is just at judgement
One of standard of mental disease.In order to study the neurobiological mechanism of mankind's Social behaviors obstacle, researcher establishes many
The animal model of Social behaviors defect.In order to study the variation of Social behaviors on animal model, experimenters have developed one
The Behaviors survey of series, wherein more mature is the social experimental box experiment for being directed to rats and mice.
The social experimental box of the prior art is divided into more lattice more, and the letter for the small gap that can guarantee that mouse passes through is arranged in centre
Easy cabinet also sets up the box body structure for placing fixed mouse, but constantly improve due to the prior art in cabinet, it is often necessary to right
It is movable corresponding with brain area with Study Mouse progress Social behaviors that brain is placed in special electrodes/optical fiber, or the small-sized microscope of configuration
Relationship；Since electrode/optical fiber of mouse merging or small-sized microscopic structure rear are mostly the structure of long line, the cabinet of the prior art
On small gap not can guarantee the mouse with long cable architecture and move freely in the cabinet of not apposition, and then cannot achieve
The research of relationship between corresponding Social behaviors and brain area activity；Cabinet in the prior art is mostly that fixed structure cannot change,
But the whole process of experiment is all in shooting recording process, and in order to study the work of the experiment mice of different colours different cultivars
It is dynamic, it usually needs the cabinet of different background colors is set, and then more cabinets are set, and the special occupied space of the placement of cabinet, into
And keep whole operation too convenient；Existing experimental box mostly uses integrity design, is required after use to entire cabinet
It is cleaned, operation is very cumbersome, increases the workload of staff.
The present invention is placed in structure mouse inconvenient activity for brain band existing for mouse social activity experimental box in the prior art,
And because mouse color difference needs to be arranged multiple experimental boxs, it is inconvenient the problems such as, a kind of mouse Social behaviors research is provided
Use experimental box.
Summary of the invention
In order to overcome mouse inconvenient activity in the prior art, cleaning is difficult and the problems such as excessive is arranged in laboratory cabinet, this
Invention provides a kind of mouse Social behaviors research experimental box.
A kind of mouse Social behaviors research experimental box comprising the cabinet of more lattice settings, fixed mouse metal strip cage,
It is characterized in that, strip notch is arranged below every lattice cabinet front, in strip notch setting can pull plate, different colours are set
Can pull plate；Can pull plate when being fully inserted into every lattice cabinet, can pull plate and cabinet be the mode stitched and fastened；Metal
The setting of bar cage is can be on pull plate；Spacing board is set between every two lattice cabinet, is arranged from pull Board position to top on spacing board
Through notch；The intracorporal metal strip cage of two adjacent lattice casees is arranged in diagonal positions.Above-mentioned setting can guarantee according to experiment
The high particular color of color setting contrast of mouse can pull plate, guarantee the validity shot when experiment, run through by setting
Notch can guarantee the cheap property of activity of the mouse with merging structure, guarantee the validity of experiment, observe the brain of mouse
Activity with the relationship of corresponding behavior, observed and recorded at any time without experimenter, reduction experimenter's workload.
Further, two kinds of colors of setting black and white can pull plate, can be needed in strip notch according to experiment
That protrudes into different colours can pull plate.
Further, strip notch is correspondingly arranged on the cabinet of the strip notch other side, by the way that corresponding length is arranged in opposite side
The mode of notch can guarantee can pull plate be placed in two notches, guarantee can pull plate structure stability.
Further, can pull plate length it is consistent with strip notch, the length of strip notch is equal to every lattice cabinet and side is arranged
Length；Such setting can guarantee can pull plate gross area layout.
Alternatively, can pull plate length it is consistent with strip notch, the length of strip notch is less than every lattice cabinet setting side
Length range is 3-10mm；And on every lattice two sidewalls of respective heights be arranged with can pull plate split stretching plate, Ci Zhongshe
Set can guarantee can pull plate account for the overwhelming majority, and then conveniently the corresponding of mouse is observed, the setting for stretching out plate may be implemented
Split is imitated, mouse falls in placement experimentation.
Further, can on the side wall of pull plate two sides setting for can the mobile shifting chute of pull plate；The setting of shifting chute can
To facilitate the movement of pull plate, and guarantee can pull plate motion track, guarantee in its motion process can pull plate structure it is steady
It is qualitative.
Further, can pull plate include front end the barrier plate for protruding into plate and rear end；Barrier plate can effectively stop strip
Notch；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.
Further, leader's structure is arranged in barrier plate rear end, guarantees the cheap property of operation.
Further, slot is set in the periphery setting barrier plate of barrier plate, guarantees that barrier plate is effectively placed, and guarantee whole knot
The stability of structure.
Further, barrier plate setting slot is made of sidewall notches or is surrounded by the coaming plate of stretching side wall.
Further, metal strip cage is cylindrical metal bar cage；More rhizospheres including middle section around setting metal column, under
Cylinder is arranged in the metal column setting ring in portion and the metal column on top；Ring setting is set and guarantees the bore that mouse is put into；Cylinder is set
For solid metal cylinder.The quality of metal strip cage can be effectively ensured in such setting, and then guarantees that metal strip cage is integrally-built
Stability prevents to shake the problem of inclination skews.
Further, the inside diameter ranges that ring is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively putting for fixed mouse
Enter.
Further, the altitude range of metal column is 80-90mm；Such height can guarantee the useful space of fixed mouse.
Further, setting columnar part height is 40-60mm, and such height setting can guarantee the whole matter of metal strip cage
Amount and height prevent to shake and mobile mouse are effectively prevent to escape from by metal strip cage.
It further, is rectangular through the bottom of notch, and width range is 60-90mm；Wherein preferable width range is
80mm。
Further, the interval plate angle through notch top two sides is set as rounded structure, and the purpose of rounded structure setting is
The linear structure on top is hung in right angle when preventing mouse by through notch, and then causes experiment that can not carry out.
Further, 4-8 insertion rod is set in metal strip cage bottom portion；In addition corresponding insertion can be set on pull plate
Hole, the purpose of such setting may further ensure that the stability of metal strip basket structure, prevent the thing toppled over.
Alternatively, setting ring bottom be arranged a magnetosphere, can pull plate corresponding position setting iron plate structure or will
Can pull plate whole installation be iron plate, by the suction-operated of magnetosphere and iron plate or iron plate, effectively fixed gold can also be played
Belong to the purpose of a cage.
Further, can the side protruded into of pull plate strip bottom of the gap setting one can pull drawer structure, can pull
And it can the perforation of pull drawer below plate.Such setting can guarantee at the end of experiment can pull plate and dump box by twitch
Body, reach by stool in mice and eventually by can pull plate and can pull drawer cleaning, complete to the clear of entire experimental box
Reason, makes entire scale removal process become simple.
Further, can pull drawer structure be arranged in every lattice bottom of box, or be arranged in all bottoms of box one big
Can pull drawer structure.
Further, when the cabinet of 3 lattice or more is arranged, every lattice bottom of box be all arranged one can pull drawer, when
When 2 lattice cabinet is set, the bottom of box be arranged it is one big by 2 lattice cabinets can pull drawer.
Further, the length range of every lattice cabinet is 25cm-32cm；Width range is 20-26cm；Altitude range is 18-
25cm；
Further, the length of every lattice cabinet is 28cm；Width is 24.2cm；Height is 20cm, and the cabinet of such size is set
Set the experiment demand that can satisfy most of experiment mice.
In use, fixed rope is placed into metal strip cage, other lint mouse can be placed on pull plate by being placed into
Into the metal strip cage of control, in contrast.Then the social mouse for putting into electrode is placed into experimental box, according to experimental mouse
What color selected suitable color can pull plate.Finally by camera shooting and the behavior of the control device being connect with electrode observation mouse
And mouse brain area activity when generation behavior.
By the setting of above-mentioned mouse social activity experimental box, can be with effective solution prior art the technical issues of, pass through
Different colours can pull plate setting, can effectively solve because the bottom of box and the small shooting effect of experimental mouse color color difference it is poor,
Or use multiple experimental box frequent operations, the problem of vacant experimental box duty；In addition, being fillet through notch by top
Setting can effectively solve the problems, such as effective activity of belt length line electrode structure mouse and long line will not be stuck；Additionally by
Can pull plate with can pull drawer be used cooperatively, can by cleaning can pull drawer and can pull plate reach cleaning and tested
The problem of mouse generates in journey excrement and urine.
Detailed description of the invention
Fig. 1 is 1 overall structure diagram of the embodiment of the present invention；
Fig. 2 is 2 overall structure diagram of the embodiment of the present invention；
Fig. 3 is 3 overall structure diagram of the embodiment of the present invention；
Fig. 4 is the overall structure diagram that the embodiment of the present invention 3 lacks a metal strip cage；
Fig. 5 is the overall structure diagram that the embodiment of the present invention 3 lacks two metal strip cages；
Fig. 6 be the present invention only comprising can pull plate, can pull drawer and metal strip cage longitudinal sectional drawing；
Fig. 7 be the present invention without can pull plate and can pull drawer body structure figure；
Fig. 8 be the present invention without can pull plate and can pull drawer body structure figure longitudinal sectional drawing；
Fig. 9 is overall structure diagram of the embodiment of the present invention 4 without metal strip cage；
Figure 10 is 4 metal strip basket structure schematic diagram of the embodiment of the present invention；
In figure, 1, cabinet；2, metal strip cage；21, metal column；22, ring is set；23, cylinder is set；24, insertion rod；25,
It is inserted into hole；26, magnetosphere；27, iron plate structure；3, strip notch；It 4, can pull plate；41, shifting chute；42, plate is protruded into；43, it hinders
Baffle；44, grip structure；45, coaming plate；5, spacing board；6, run through notch；61, rounded structure；7, plate is stretched out；It 8, can pull pumping
Drawer structure.
Specific embodiment
Experimental box is used in a kind of research of the mouse Social behaviors of embodiment 1
A kind of mouse Social behaviors research experimental box comprising the cabinet 1 of 2 lattice setting, fixed mouse metal strip cage
2, wherein strip notch 3 is arranged from 1 front side lower section of every lattice cabinet, in strip notch 3 setting can pull plate 4, different colours are set
Can pull plate 4；Can pull plate 4 when being fully inserted into every lattice cabinet 1, can pull plate 4 and cabinet 1 be the side stitched and fastened
Formula；The setting of metal strip cage 2 is can be on pull plate 4；Spacing board 5 is set between every two lattice cabinet 1, is arranged on spacing board 5 from pull plate
Notch 6 is run through to top in position；The diagonal positions of entire cabinet 1 are arranged in metal strip cage 2, and the setting of diagonal positions can
To guarantee maximum separating distance, the error in experimentation is reduced.Above-mentioned setting can guarantee to be set according to the color of experimental mouse
Determine the high particular color of contrast can pull plate 4, guarantee the validity that shoots when experiment, can be with through notch 6 by setting
The cheap property of activity for guaranteeing the mouse with merging structure, guarantees the validity of experiment, observe the brain activity of mouse with it is right
The relationship for answering behavior observes and records at any time without experimenter, reduces experimenter's workload.Black and white two kinds of face are set
Color can pull plate 4, can need protrude into strip notch 3 different colours according to experiment can pull plate 4.
It is correspondingly arranged strip notch 3 on the cabinet 1 of 3 other side of strip notch, is lacked by the way that corresponding strip is arranged in opposite side
Mouthfuls 3 mode can guarantee can pull plate 4 be placed in two notches, guarantee can 4 structure of pull plate stability.It can pull plate
4 length and strip notch 3 is consistent, and the length range that the length of strip notch 3 is less than every lattice cabinet 1 setting side is 3-10mm；
And on every lattice two sidewalls of respective heights be arranged with can 4 split of pull plate stretching plate 7, such setting can guarantee can pull
Plate 4 accounts for the overwhelming majority, and then conveniently observes the corresponding of mouse, and effective split may be implemented in the setting for stretching out plate 7, places experiment
Mouse falls in the process.
It can the barrier plate 43 that protrudes into plate 42 and rear end of the pull plate 4 including front end；Barrier plate 43 can effectively stop strip
Notch 3；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.Leader's structure is arranged in 43 rear end of barrier plate
44, guarantee the cheap property of operation.Slot is set in the periphery setting barrier plate 43 of barrier plate 43, guarantees that barrier plate 43 is effectively placed,
And guarantee the stability of total.Barrier plate 43 is arranged slot and is made of sidewall notches or is enclosed by the coaming plate 45 of stretching side wall
At.
Metal strip cage 2 is cylindrical metal bar cage 2；Metal column 21 of the more rhizospheres including middle section around setting, lower part
Metal column 21 metal column 21 on ring 22 and top is set cylinder 23 is set；The setting of ring 22 is set and guarantees the bore that mouse is put into；
Setting cylinder 23 is 21 body of solid metal column.The quality of metal strip cage 2 can be effectively ensured in such setting, and then guarantees metal strip
The integrally-built stability of cage 2 prevents to shake the problem of inclination skews.
The inside diameter ranges that ring 22 is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively being put into for fixed mouse.Gold
The altitude range for belonging to column 21 is 80-90mm；Such height can guarantee the useful space of fixed mouse.23 Partial Height of cylinder is set
For 40-60mm, such height setting can guarantee the total quality and height of metal strip cage 2, prevent to shake and effectively prevent
Mouse is only moved to escape from by metal strip cage 2.
It is rectangular through the bottom of notch 6, and width range is 60-90mm；Wherein preferable width range is 80mm.Run through
5 jiaos of spacing board of 6 top two sides of notch are set as rounded structure 61, and mouse passes through the purpose that rounded structure 61 is arranged in order to prevent
The linear structure on top is hung in right angle when through notch 6, and then causes experiment that can not carry out.The length of every lattice cabinet 1 is
28cm；Width is 24.2cm；Height is 20cm, and the experiment that can satisfy most of experiment mice is arranged in the cabinet 1 of such size
Demand
Experimental box is used in a kind of research of the mouse Social behaviors of embodiment 2
A kind of mouse Social behaviors research experimental box comprising the cabinet 1 of 2 lattice setting, fixed mouse metal strip cage
2, wherein strip notch 3 is arranged from 1 front side lower section of every lattice cabinet, in strip notch 3 setting can pull plate 4, different colours are set
Can pull plate 4；Can pull plate 4 when being fully inserted into every lattice cabinet 1, can pull plate 4 and cabinet 1 be the side stitched and fastened
Formula；The setting of metal strip cage 2 is can be on pull plate 4；Spacing board 5 is set between every two lattice cabinet 1, is arranged on spacing board 5 from pull plate
Notch 6 is run through to top in position；The diagonal positions of entire cabinet 1 are arranged in metal strip cage 2, and the setting of diagonal positions can
To guarantee maximum separating distance, the error in experimentation is reduced.Above-mentioned setting can guarantee to be set according to the color of experimental mouse
Determine the high particular color of contrast can pull plate 4, guarantee the validity that shoots when experiment, can be with through notch 6 by setting
The cheap property of activity for guaranteeing the mouse with merging structure, guarantees the validity of experiment, observe the brain activity of mouse with it is right
The relationship for answering behavior observes and records at any time without experimenter, reduces experimenter's workload.Black and white two kinds of face are set
Color can pull plate 4, can need protrude into strip notch 3 different colours according to experiment can pull plate 4.
It is correspondingly arranged strip notch 3 on the cabinet 1 of 3 other side of strip notch, is lacked by the way that corresponding strip is arranged in opposite side
Mouthfuls 3 mode can guarantee can pull plate 4 be placed in two notches, guarantee can 4 structure of pull plate stability.It can pull plate
4 length and strip notch 3 is consistent, and the length of strip notch 3 is equal to the length of every lattice cabinet 1 setting side；Such setting can be with
Guarantee can pull plate 4 gross area layout.
Can on the side wall of 4 two sides of pull plate setting for can the mobile shifting chute 41 of pull plate 4；The setting of shifting chute 41 can be with
Facilitate the movement of pull plate, and guarantee can pull plate 4 motion track, guarantee in its motion process can 4 structure of pull plate it is steady
It is qualitative.
It can the barrier plate 43 that protrudes into plate 42 and rear end of the pull plate 4 including front end；Barrier plate 43 can effectively stop strip
Notch 3；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.Leader's structure is arranged in 43 rear end of barrier plate
44, guarantee the cheap property of operation.Slot is set in the periphery setting barrier plate 43 of barrier plate 43, guarantees that barrier plate 43 is effectively placed,
And guarantee the stability of total.Barrier plate 43 is arranged slot and is made of sidewall notches or is enclosed by the coaming plate 45 of stretching side wall
At.
Metal strip cage 2 is cylindrical metal bar cage 2；Metal column 21 of the more rhizospheres including middle section around setting, lower part
Metal column 21 metal column 21 on ring 22 and top is set cylinder 23 is set；The setting of ring 22 is set and guarantees the bore that mouse is put into；
Setting cylinder 23 is 21 body of solid metal column.The quality of metal strip cage 2 can be effectively ensured in such setting, and then guarantees metal strip
The integrally-built stability of cage 2 prevents to shake the problem of inclination skews.
The inside diameter ranges that ring 22 is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively being put into for fixed mouse.Gold
The altitude range for belonging to column 21 is 80-90mm；Such height can guarantee the useful space of fixed mouse.23 Partial Height of cylinder is set
For 40-60mm, such height setting can guarantee the total quality and height of metal strip cage 2, prevent to shake and effectively prevent
Mouse is only moved to escape from by metal strip cage 2.
It is rectangular through the bottom of notch 6, and width range is 60-90mm；Wherein preferable width range is 80mm.Run through
5 jiaos of spacing board of 6 top two sides of notch are set as rounded structure 61, and mouse passes through the purpose that rounded structure 61 is arranged in order to prevent
The linear structure on top is hung in right angle when through notch 6, and then causes experiment that can not carry out.
Can below the strip notch 3 of side that protrudes into of pull plate 4 setting one can pull drawer structure 8, can be under pull plate 4
The perforation of Fang Yuke pull drawer.Such setting can guarantee that pull plate 4 and cabinet 1 can be tilted by twitching at the end of experiment,
Reach by stool in mice and eventually by can pull plate 4 and can pull drawer cleaning, complete cleaning to entire experimental box,
Entire scale removal process is set to become simple.All 1 bottoms of cabinet be arranged it is one big can pull drawer structure 8.Every lattice cabinet 1
Length is 28cm；Width is 24.2cm；Height is 20cm, and the setting of cabinet 1 of such size can satisfy most of experiment mice
Experiment demand.
Experimental box is used in a kind of research of the mouse Social behaviors of embodiment 3
A kind of mouse Social behaviors research experimental box comprising the cabinet 1 of 2 lattice setting, fixed mouse metal strip cage
2, wherein strip notch 3 is arranged from 1 front side lower section of every lattice cabinet, in strip notch 3 setting can pull plate 4, different colours are set
Can pull plate 4；Can pull plate 4 when being fully inserted into every lattice cabinet 1, can pull plate 4 and cabinet 1 be the side stitched and fastened
Formula；The setting of metal strip cage 2 is can be on pull plate 4；Spacing board 5 is set between every two lattice cabinet 1, is arranged on spacing board 5 from pull plate
Notch 6 is run through to top in position；The diagonal positions of entire cabinet 1 are arranged in metal strip cage 2, and the setting of diagonal positions can
To guarantee maximum separating distance, the error in experimentation is reduced.Above-mentioned setting can guarantee to be set according to the color of experimental mouse
Determine the high particular color of contrast can pull plate 4, guarantee the validity that shoots when experiment, can be with through notch 6 by setting
The cheap property of activity for guaranteeing the mouse with merging structure, guarantees the validity of experiment, observe the brain activity of mouse with it is right
The relationship for answering behavior observes and records at any time without experimenter, reduces experimenter's workload.Black and white two kinds of face are set
Color can pull plate 4, can need protrude into strip notch 3 different colours according to experiment can pull plate 4.
It is correspondingly arranged strip notch 3 on the cabinet 1 of 3 other side of strip notch, is lacked by the way that corresponding strip is arranged in opposite side
Mouthfuls 3 mode can guarantee can pull plate 4 be placed in two notches, guarantee can 4 structure of pull plate stability.
Can pull plate 4 length and strip notch 3 it is consistent, the length of strip notch 3 is equal to the length of every lattice cabinet 1 setting side
Degree；Such setting can guarantee can pull plate 4 gross area layout.
Can on the side wall of 4 two sides of pull plate setting for can the mobile shifting chute 41 of pull plate 4；The setting of shifting chute 41 can be with
Facilitate the movement of pull plate, and guarantee can pull plate 4 motion track, guarantee in its motion process can 4 structure of pull plate it is steady
It is qualitative.
It can the barrier plate 43 that protrudes into plate 42 and rear end of the pull plate 4 including front end；Barrier plate 43 can effectively stop strip
Notch 3；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.Leader's structure is arranged in 43 rear end of barrier plate
44, guarantee the cheap property of operation.Slot is set in the periphery setting barrier plate 43 of barrier plate 43, guarantees that barrier plate 43 is effectively placed,
And guarantee the stability of total.Barrier plate 43 is arranged slot and is made of sidewall notches or is enclosed by the coaming plate 45 of stretching side wall
At.
Metal strip cage 2 is cylindrical metal bar cage 2；Metal column 21 of the more rhizospheres including middle section around setting, lower part
Metal column 21 metal column 21 on ring 22 and top is set cylinder 23 is set；The setting of ring 22 is set and guarantees the bore that mouse is put into；
Setting cylinder 23 is 21 body of solid metal column.The quality of metal strip cage 2 can be effectively ensured in such setting, and then guarantees metal strip
The integrally-built stability of cage 2 prevents to shake the problem of inclination skews.
The inside diameter ranges that ring 22 is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively being put into for fixed mouse.Gold
The altitude range for belonging to column 21 is 80-90mm；Such height can guarantee the useful space of fixed mouse.23 Partial Height of cylinder is set
For 40-60mm, such height setting can guarantee the total quality and height of metal strip cage 2, prevent to shake and effectively prevent
Mouse is only moved to escape from by metal strip cage 2.
It is rectangular through the bottom of notch 6, and width range is 60-90mm；Wherein preferable width range is 80mm.Run through
5 jiaos of spacing board of 6 top two sides of notch are set as rounded structure 61, and mouse passes through the purpose that rounded structure 61 is arranged in order to prevent
The linear structure on top is hung in right angle when through notch 6, and then causes experiment that can not carry out.
In 2 bottom of metal strip cage, 4-8 insertion rod 24 is set；In addition corresponding insertion hole 25 can be set on pull plate 4,
The purpose of such setting may further ensure that the stability of 2 structure of metal strip cage, prevent the thing toppled over.
All 1 bottoms of cabinet be arranged it is one big can pull drawer structure 8, can the side protruded into of pull plate 4 to be arranged in
The one of the lower section of strip notch 3 in face can pull drawer structure 8, can 4 lower section of pull plate with can pull drawer penetrate through.Such setting can
To guarantee pull plate 4 and cabinet 1 can be tilted by twitching at the end of experiment, reach by stool in mice and eventually by can take out
Pulling plate 4 and can pull drawer cleaning, complete cleaning to entire experimental box, entire scale removal process made to become simple.Every lattice case
The length of body 1 is 28cm；Width is 24.2cm；Height is 20cm, and the setting of cabinet 1 of such size can satisfy most of experiment
The experiment demand of mouse.
Experimental box is used in a kind of research of the mouse Social behaviors of embodiment 4
A kind of mouse Social behaviors research experimental box comprising the cabinet 1 of 2 lattice setting, fixed mouse metal strip cage
2, wherein strip notch 3 is arranged from 1 front side lower section of every lattice cabinet, in strip notch 3 setting can pull plate 4, different colours are set
Can pull plate 4；Can pull plate 4 when being fully inserted into every lattice cabinet 1, can pull plate 4 and cabinet 1 be the side stitched and fastened
Formula；The setting of metal strip cage 2 is can be on pull plate 4；Spacing board 5 is set between every two lattice cabinet 1, is arranged on spacing board 5 from pull plate
Notch 6 is run through to top in position；The diagonal positions of entire cabinet 1 are arranged in metal strip cage 2, and the setting of diagonal positions can
To guarantee maximum separating distance, the error in experimentation is reduced.Above-mentioned setting can guarantee to be set according to the color of experimental mouse
Determine the high particular color of contrast can pull plate 4, guarantee the validity that shoots when experiment, can be with through notch 6 by setting
The cheap property of activity for guaranteeing the mouse with merging structure, guarantees the validity of experiment, observe the brain activity of mouse with it is right
The relationship for answering behavior observes and records at any time without experimenter, reduces experimenter's workload.Black and white two kinds of face are set
Color can pull plate 4, can need protrude into strip notch 3 different colours according to experiment can pull plate 4.
It is correspondingly arranged strip notch 3 on the cabinet 1 of 3 other side of strip notch, is lacked by the way that corresponding strip is arranged in opposite side
Mouthfuls 3 mode can guarantee can pull plate 4 be placed in two notches, guarantee can 4 structure of pull plate stability.It can pull plate
4 length and strip notch 3 is consistent, and the length of strip notch 3 is equal to the length of every lattice cabinet 1 setting side；Such setting can be with
Guarantee can pull plate 4 gross area layout.
Can on the side wall of 4 two sides of pull plate setting for can the mobile shifting chute 41 of pull plate 4；The setting of shifting chute 41 can be with
Facilitate the movement of pull plate, and guarantee can pull plate 4 motion track, guarantee in its motion process can 4 structure of pull plate it is steady
It is qualitative.
It can the barrier plate 43 that protrudes into plate 42 and rear end of the pull plate 4 including front end；Barrier plate 43 can effectively stop strip
Notch 3；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.Leader's structure is arranged in 43 rear end of barrier plate
44, guarantee the cheap property of operation.Slot is set in the periphery setting barrier plate 43 of barrier plate 43, guarantees that barrier plate 43 is effectively placed,
And guarantee the stability of total.Barrier plate 43 is arranged slot and is made of sidewall notches or is enclosed by the coaming plate 45 of stretching side wall
At.
Metal strip cage 2 is cylindrical metal bar cage 2；Metal column 21 of the more rhizospheres including middle section around setting, lower part
Metal column 21 metal column 21 on ring 22 and top is set cylinder 23 is set；The setting of ring 22 is set and guarantees the bore that mouse is put into；
Setting cylinder 23 is 21 body of solid metal column.The quality of metal strip cage 2 can be effectively ensured in such setting, and then guarantees metal strip
The integrally-built stability of cage 2 prevents to shake the problem of inclination skews.
The inside diameter ranges that ring 22 is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively being put into for fixed mouse.Gold
The altitude range for belonging to column 21 is 80-90mm；Such height can guarantee the useful space of fixed mouse.23 Partial Height of cylinder is set
For 40-60mm, such height setting can guarantee the total quality and height of metal strip cage 2, prevent to shake and effectively prevent
Mouse is only moved to escape from by metal strip cage 2.
It is rectangular through the bottom of notch 6, and width range is 60-90mm；Wherein preferable width range is 80mm.Run through
5 jiaos of spacing board of 6 top two sides of notch are set as rounded structure 61, and mouse passes through the purpose that rounded structure 61 is arranged in order to prevent
The linear structure on top is hung in right angle when through notch 6, and then causes experiment that can not carry out.
Setting 22 bottom of ring be arranged a magnetosphere 26, can pull plate 4 corresponding position setting iron plate structure 27 or
Can 4 whole installation of pull plate be iron plate, by the suction-operated of magnetosphere 26 and iron plate or iron plate, can also play effectively solid
Determine the purpose of metal strip cage 2.
All 1 bottoms of cabinet be arranged it is one big can pull drawer structure 8, can the side protruded into of pull plate 4 to be arranged in
The one of the lower section of strip notch 3 in face can pull drawer structure 8, can 4 lower section of pull plate with can pull drawer penetrate through.Such setting can
To guarantee pull plate 4 and cabinet 1 can be tilted by twitching at the end of experiment, reach by stool in mice and eventually by can take out
Pulling plate 4 and can pull drawer cleaning, complete cleaning to entire experimental box, entire scale removal process made to become simple.Every lattice case
The length of body 1 is 28cm；Width is 24.2cm；Height is 20cm, and the setting of cabinet 1 of such size can satisfy most of experiment
The experiment demand of mouse.
Experimental box is used in a kind of research of the mouse Social behaviors of embodiment 5
A kind of mouse Social behaviors research experimental box comprising the cabinet 1 of 3 lattice setting, fixed mouse metal strip cage
2, wherein strip notch 3 is arranged from 1 front side lower section of every lattice cabinet, in strip notch 3 setting can pull plate 4, different colours are set
Can pull plate 4；Can pull plate 4 when being fully inserted into every lattice cabinet 1, can pull plate 4 and cabinet 1 be the side stitched and fastened
Formula；The setting of metal strip cage 2 is can be on pull plate 4；Spacing board 5 is set between every two lattice cabinet 1, is arranged on spacing board 5 from pull plate
Notch 6 is run through to top in position；The diagonal positions of every adjacent two lattice cabinet 1 are arranged in metal strip cage 2, diagonal positions
Setting can guarantee maximum separating distance, reduce the error in experimentation.Above-mentioned setting can guarantee according to experimental mouse
Color set the high particular color of contrast can pull plate 4, guarantee the validity shot when experiment, notch run through by setting
6 can guarantee the cheap property of activity of the mouse with merging structure, guarantee the validity of experiment, observe the brain activity of mouse
It with the relationship of corresponding behavior, is observed and recorded at any time without experimenter, reduces experimenter's workload.Black and white two are set
Kind of color can pull plate 4, can need protrude into different colours in strip notch 3 according to experiment can pull plate 4.
It is correspondingly arranged strip notch 3 on the cabinet 1 of 3 other side of strip notch, is lacked by the way that corresponding strip is arranged in opposite side
Mouthfuls 3 mode can guarantee can pull plate 4 be placed in two notches, guarantee can 4 structure of pull plate stability.
Can pull plate 4 length and strip notch 3 it is consistent, the length of strip notch 3 is equal to the length of every lattice cabinet 1 setting side
Degree；Such setting can guarantee can pull plate 4 gross area layout.
Can on the side wall of 4 two sides of pull plate setting for can the mobile shifting chute 41 of pull plate 4；The setting of shifting chute 41 can be with
Facilitate the movement of pull plate, and guarantee can pull plate 4 motion track, guarantee in its motion process can 4 structure of pull plate it is steady
It is qualitative.
It can the barrier plate 43 that protrudes into plate 42 and rear end of the pull plate 4 including front end；Barrier plate 43 can effectively stop strip
Notch 3；Blocking for excrement or mouse four limbs can be effectively prevented in such setting.Leader's structure is arranged in 43 rear end of barrier plate
44, guarantee the cheap property of operation.Slot is set in the periphery setting barrier plate 43 of barrier plate 43, guarantees that barrier plate 43 is effectively placed,
And guarantee the stability of total.Barrier plate 43 is arranged slot and is made of sidewall notches or is enclosed by the coaming plate 45 of stretching side wall
At.
Metal strip cage 2 is cylindrical metal bar cage 2；Metal column 21 of the more rhizospheres including middle section around setting, lower part
Metal column 21 metal column 21 on ring 22 and top is set cylinder 23 is set；The setting of ring 22 is set and guarantees the bore that mouse is put into；
Setting cylinder 23 is 21 body of solid metal column.The quality of metal strip cage 2 can be effectively ensured in such setting, and then guarantees metal strip
The integrally-built stability of cage 2 prevents to shake the problem of inclination skews.
The inside diameter ranges that ring 22 is arranged are 90mm-120mm；The setting of this internal diameter can guarantee effectively being put into for fixed mouse.Gold
The altitude range for belonging to column 21 is 80-90mm；Such height can guarantee the useful space of fixed mouse.23 Partial Height of cylinder is set
For 40-60mm, such height setting can guarantee the total quality and height of metal strip cage 2, prevent to shake and effectively prevent
Mouse is only moved to escape from by metal strip cage 2.
It is rectangular through the bottom of notch 6, and width range is 60-90mm；Wherein preferable width range is 80mm.Run through
5 jiaos of spacing board of 6 top two sides of notch are set as rounded structure 61, and mouse passes through the purpose that rounded structure 61 is arranged in order to prevent
The linear structure on top is hung in right angle when through notch 6, and then causes experiment that can not carry out.
Setting 22 bottom of ring be arranged a magnetosphere 26, can pull plate 4 corresponding position setting iron plate structure 27 or
Can 4 whole installation of pull plate be iron plate, by the suction-operated of magnetosphere 26 and iron plate or iron plate, can also play effectively solid
Determine the purpose of metal strip cage 2.
In every lattice cabinet 1, can setting one can pull drawer structure below the strip notch 3 of side that protrudes into of pull plate 4
8, can the lower section of pull plate 4 with can pull drawer penetrate through, can pull drawer structure 8 be arranged in every 1 bottom of lattice cabinet.Such setting can
To guarantee pull plate 4 and cabinet 1 can be tilted by twitching at the end of experiment, reach by stool in mice and eventually by can take out
Pulling plate 4 and can pull drawer cleaning, complete cleaning to entire experimental box, entire scale removal process made to become simple.Every lattice case
The length of body 1 is 28cm；Width is 24.2cm；Height is 20cm, and the setting of cabinet 1 of such size can satisfy most of experiment
The experiment demand of mouse.
The explanation of above-described embodiment is only intended to understand the present invention.It should be pointed out that for those of ordinary skill in the art
For, without departing from the principle of the present invention, several improvement can also be carried out to the present invention, these improvement will also fall into this
In invention scope of protection of the claims.
Claims (10)
1. a kind of mouse Social behaviors research experimental box comprising the cabinet (1) of more lattice settings, fixed mouse metal strip cage
(2), which is characterized in that strip notch (3) are arranged in lower section on front side of every lattice cabinet (1), and setting can pull plate in strip notch (3)
(4), be arranged different colours can pull plate (4)；Can pull plate (4) be fully inserted into every lattice cabinet (1) it is interior when, can pull plate (4)
It is the mode stitched and fastened with cabinet (1)；Metal strip cage (2) setting is can be on pull plate (4)；It is set between every two lattice cabinet (1)
It sets spacing board (5), is arranged on spacing board (5) and runs through notch (6) from pull Board position to top；Two adjacent lattice cabinets (1)
Interior metal strip cage (2) is arranged in diagonal positions.
2. mouse Social behaviors research experimental box according to claim 1, which is characterized in that another in strip notch (3)
Strip notch (3) are correspondingly arranged on the cabinet (1) of side.
3. mouse Social behaviors according to claim 2 research experimental box, which is characterized in that can pull plate (4) length
Unanimously with strip notch (3), the length of strip notch (3) is equal to the length of every lattice cabinet (1) setting side to degree；Or it can pull plate
(4) unanimously with strip notch (3), the length range that the length of strip notch (3) is less than every lattice cabinet (1) setting side is length
3-10mm；And on every lattice two sidewalls of respective heights be arranged with can pull plate (4) split stretching plate (7).
4. mouse Social behaviors research experimental box according to claim 3, which is characterized in that can pull plate (4) two sides
Side wall on setting for can the mobile shifting chute (41) of pull plate (4).
5. mouse Social behaviors research experimental box according to claim 1, which is characterized in that metal strip cage (2) is circle
Cylindricality metal strip cage (2)；Metal column (21) of the more rhizospheres including middle section around setting, metal column (21) the setting ring of lower part
(22) and cylinder (23) are arranged in the metal column on top (21)；Ring (22) setting is set and guarantees the bore that mouse is put into；Cylinder is set
It (23) is solid metal column (21) body.
6. mouse Social behaviors research experimental box according to claim 1, which is characterized in that run through the bottom of notch (6)
Portion is rectangular, and width range is 60-90mm；And rounded structure is set as through spacing board (5) angle of notch (6) top two sides
(61)。
7. mouse Social behaviors research experimental box according to claim 1, which is characterized in that at metal strip cage (2) bottom
4-8 insertion rod (24) is arranged in portion；In addition corresponding insertion hole (25) can be set on pull plate (4)；Alternatively, in setting ring
(22) bottom setting one magnetosphere (26), can pull plate (4) corresponding position setting iron plate structure (27) or can pull
Plate (4) whole installation is iron plate.
8. the research of mouse Social behaviors described in -7 any one experimental box according to claim 1, which is characterized in that can take out
Below the strip notch (3) of the side that pulling plate (4) protrudes into setting one can pull drawer structure (8), can below pull plate (4) with can
The perforation of pull drawer.
9. mouse Social behaviors research experimental box according to claim 8, which is characterized in that can pull drawer structure
(8) be arranged in every lattice cabinet (1) bottom, or all cabinets (1) bottom be arranged it is one big can pull drawer structure (8).
10. the research of mouse Social behaviors described in -7 any one experimental box according to claim 1, which is characterized in that every lattice
The length range of cabinet (1) is 25cm-32cm；Width range is 20-26cm；Altitude range is 18-25cm.
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