CN210115079U - Liquid separation sample injector - Google Patents

Liquid separation sample injector Download PDF

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Publication number
CN210115079U
CN210115079U CN201920767833.9U CN201920767833U CN210115079U CN 210115079 U CN210115079 U CN 210115079U CN 201920767833 U CN201920767833 U CN 201920767833U CN 210115079 U CN210115079 U CN 210115079U
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sample
liquid
liquid storage
tube
quantitative
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徐茂锁
申春梅
贺乐奇
韩晓洁
沈芳
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SHANGHAI NO 5 PEOPLE'S HOSPITAL
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SHANGHAI NO 5 PEOPLE'S HOSPITAL
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Abstract

The utility model discloses a divide liquid application of sample ware for divide liquid and application of sample operation in the biosafety cabinet, include: the liquid storage pipe is used for storing the pretreatment liquid; one end of the sample adding rod is provided with a sample adding piston matched with the liquid storage tube, and one end of the sample adding rod, which is provided with the sample adding piston, moves in the sample adding tube; the pipette is communicated with the liquid storage pipe and samples are added into the liquid storage pipe; and the sample adding pipe is communicated with the liquid storage pipe, and the pretreatment liquid in the liquid storage pipe is added into the specimen container. The utility model discloses technical scheme's branch liquid application of sample ware can collect and divide two kinds of functions of liquid and application of sample as an organic whole, and has saved the sample link of inhaling in the past, has simplified operating procedure to stop cross contamination's possibility, improved the accuracy of experimental result, realized the branch liquid and the continuous application of sample function of ration liquid, can operate the different liquid feeding volume between the different samples, very big improvement work efficiency.

Description

Liquid separation sample injector
Technical Field
The utility model relates to an experimental facilities field especially relates to a divide liquid application of sample ware.
Background
The biosafety cabinet is a common device in a medical laboratory, and has the function of preventing the aerosol from dissipating when operating samples containing potential pathogenic microorganisms or other dangerous factors, and when the clinical biosafety cabinet is used in a clinical microbiology room to operate clinical sputum samples, the sputum needs to be treated by pretreatment liquid.
The traditional sample adding method of the pretreatment solution has four modes: (1) using purchased or self-prepared small portions of treatment fluid, which, due to the need for aseptic manipulation, require autoclaving, sterilization and stoppering for use; (2) pouring and adding samples by using a treatment liquid bottle or adding samples by using a washing bottle cap, but the sample adding amount cannot be accurately controlled in the pouring and adding process, liquid is easy to spill and cross contamination is caused, and the extrusion and the sample adding are troublesome and laborious; (3) the sample is added by using the sample adding gun, and because of the particularity of operating pathogenic microorganisms in the biological safety cabinet, the sample is added by using the traditional sample adding gun, the sample sucking and sample adding processes need to be repeated continuously, gas flows exist in the safety cabinet, the sample adding operation is complicated, and the pretreatment pollution is easily caused, so that the accuracy of an experimental result is influenced; (4) the traditional liquid separator is used for sample adding, although the commonly used bottleneck liquid separator has the characteristics of convenience and rapidness in sample adding, the sample adding is heavy due to the space limitation of the biological safety cabinet, the position of the sample adding port is not well held, and the sample adding in a common sputum cup is easy to overflow and splash.
SUMMERY OF THE UTILITY MODEL
In view of the defects of the prior art, the utility model discloses technical scheme solves that the application of sample mode process of current preliminary treatment liquid is loaded down with trivial details, and the application of sample volume is not controlled well, easily takes place liquid and spills, and very easily causes the pollution of preliminary treatment to influence the technical problem of the accuracy of experimental result.
In order to solve the technical problem, the utility model provides a divide liquid application of sample ware for include in the biological safety cabinet: the liquid storage pipe is used for storing the pretreatment liquid; one end of the sample adding rod is provided with a sample adding piston matched with the liquid storage tube, and one end of the sample adding rod, which is provided with the sample adding piston, moves in the sample adding tube; the pipette is communicated with the liquid storage pipe and samples are added into the liquid storage pipe; and the sample adding pipe is communicated with the liquid storage pipe, and the pretreatment liquid in the liquid storage pipe is added into the specimen container.
Optionally, the liquid separating and sample adding device further comprises a housing, the liquid storage tube is located in the housing, and the sample adding rod, the liquid suction tube and the sample adding tube all penetrate through the housing.
Optionally, an elastic component is arranged in the shell, and one end of the sample adding piston, which is arranged on the sample adding rod, sequentially penetrates through the shell and the elastic component and extends into the liquid storage tube.
Optionally, divide liquid injector still include quantitative subassembly, quantitative subassembly includes ration screw rod and ration track groove, ration track groove is located the liquid storage tube is close to on the pipe wall of mouth of pipe one end and ration track groove is followed the axial setting of liquid storage tube, the ration screw rod runs through in proper order the shell ration track groove stretches into in the liquid storage tube, be equipped with an obstacle on the pole wall of application of sample pole, the obstacle contacts during the ration screw rod, application of sample pole stop moving.
Optionally, the quantitative screw is screwed and fixed with the housing and the quantitative rail groove through threads.
Optionally, the quantitative assembly further comprises a fixed gasket, and the quantitative screw penetrates through the fixed gasket, the housing and the quantitative rail groove in sequence.
Optionally, the liquid separation sample injector further comprises a gun head withdrawing device, the gun head withdrawing device comprises a gun head withdrawing sleeve, a gun head withdrawing handle and a connecting rod, the gun head withdrawing sleeve is sleeved on the pipe wall of the sample injection pipe, and the gun head withdrawing sleeve is connected with the gun head withdrawing handle through the connecting rod.
Optionally, a guide groove is formed in the axial direction of the housing, and the handle for withdrawing the gun head penetrates through the guide groove and is connected with the connecting rod.
Optionally, a pipe orifice of the sample adding pipe is sleeved with a disposable gun head, and the sample adding pipe adds the pretreatment liquid into the sample container through the disposable gun head.
Optionally, the pipette and the sample adding pipe are both provided with one-way valves.
Compared with the prior art, the utility model discloses following beneficial technological effect has:
the utility model discloses technical scheme's branch liquid application of sample ware is through changing the suction and the derivation of the interior preliminary treatment liquid of position control stock solution pipe of application of sample pole in the stock solution pipe, presses the application of sample pole and carries out the application of sample operation, and the pull application of sample pole carries out the imbibition operation, saves imbibition step in the past, avoids the repeated pollution of the preliminary treatment that the appearance caused of inhaling, has improved the accuracy of experimental result.
An elastic component is arranged in the shell, the sample adding rod sequentially penetrates through the shell and the elastic component, and after the sample adding rod is pressed to reach a preset position, the sample adding step is completed; the sample adding rod is loosened, the sample adding rod automatically restores to the original position under the action of the elastic component, and the sample sucking step is completed, so that continuous sample adding is realized, and the working efficiency is greatly improved.
Set up quantitative subassembly, control that can be accurate adds the appearance volume, all be equipped with the check valve of control fluid trend on pipette, the appearance pipe that adds, improved the accuracy of dividing the liquid application of sample.
The nozzle cover of application of sample pipe is equipped with disposable rifle head, makes the utility model discloses technical scheme's branch liquid application of sample ware can operate the sample that has the pollution sources.
The arrangement of the gun head withdrawing device can facilitate the removal of the disposable gun head only by pressing the gun head withdrawing handle when the disposable gun head needs to be replaced, and the manual removal is not needed.
To sum up, the utility model discloses technical scheme's branch liquid application of sample ware can collect and divide two kinds of functions of liquid and application of sample as an organic whole, and has saved the original sample link of inhaling, has simplified the operating procedure to stop cross contamination's possibility, improved the accuracy of experimental result, realized the branch liquid of ration liquid and continuous application of sample function, can operate the different liquid feeding volume between the different specimens, very big improvement work efficiency.
Drawings
Fig. 1 is a schematic structural diagram of a sample separating and adding device according to an embodiment of the present invention;
fig. 2 is a front view of a dosing assembly according to an embodiment of the invention;
fig. 3 is a side view of a dosing assembly in accordance with an embodiment of the present invention.
Detailed Description
As shown in fig. 1, the sample divider and injector according to the embodiment of the present invention can be applied to other situations requiring sample injection besides being applied to the biosafety cabinet. It mainly comprises a liquid storage tube 1, a sample adding rod 2, a liquid suction tube 3 and a sample adding tube 4.
Wherein, liquid storage tube 1 is used for storing preliminary treatment liquid, and application of sample pole 2 is used for extrudeing preliminary treatment liquid, carries out the application of sample, and the one end of application of sample pole 2 is equipped with liquid storage tube 1 assorted application of sample piston 21, and the one end that is equipped with application of sample piston 21 on application of sample pole 2 removes in liquid storage tube 1, is similar to the piston motion, and application of sample piston 21 extrudees preliminary treatment liquid and makes its discharge liquid storage tube 1. The end of the sample adding rod 2 opposite to the sample adding piston 21 is also provided with a sample adding handle 22, which is convenient for operation.
Pipette 3 and stock solution pipe 1 intercommunication, when application of sample pole 2 reachs predetermined position in the stock solution pipe 1, the process that application of sample pole 2 moved back is equivalent to the imbibition process, and preliminary treatment liquid passes through in pipette 3 gets into stock solution pipe 1, accomplishes the operation of inhaling the appearance, prepares for the application of sample next time.
Sample adding pipe 4 and stock solution pipe 1 intercommunication, sample adding rod 2 is when the preliminary treatment liquid in the extrusion stock solution pipe 1, and preliminary treatment liquid passes through liquid adding pipe 4 and adds to the sample container.
The liquid suction pipe 3 is provided with a check valve 31, and the sample adding pipe 4 is provided with a check valve 41. When the sample adding operation is performed, the check valve 31 is closed to prevent the pretreatment liquid from flowing back to the pipette 3, and the check valve 41 is opened simultaneously to allow the pretreatment liquid in the sample adding tube 4 to flow to the sample container through the check valve 41 smoothly. When the sample sucking operation is performed, the check valve 41 is closed, the sample adding liquid in the pipette 4 is prevented from flowing backwards, so that the sample adding amount cannot be measured, and the check valve 31 is opened, so that the pretreatment liquid is refilled in the liquid storage tube 1 through the pipette 3.
Referring to fig. 1, in order to assemble the components, a housing 11 is further provided, wherein the liquid storage tube 1 is located in the housing 11, and the sample adding rod 2, the liquid suction tube 3 and the sample adding tube 4 all penetrate through the housing 11.
Furthermore, an elastic member 12 is arranged in the housing 11, one end of the sample addition rod 2, which is provided with the sample addition piston, penetrates through the housing 11 and the elastic member 12 in sequence, and the elastic member 12 is, for example, a spring. After the sample adding rod 2 is pressed to reach a preset position, the sample adding rod 2 is loosened, the sample adding rod 2 can automatically recover to the original position under the action of the elastic component 12, and the sample sucking step is completed once in the process of recovering the original position of the sample adding rod 2, so that the original complicated sample sucking step is omitted.
In addition, the shell 11 can be also provided with a hook 14, so that the liquid separation sample injector can be suspended in the biological safety cabinet, and the space is saved.
Combine fig. 2 and fig. 3 to show, in order to improve the application of sample and the precision of dividing the appearance, the utility model discloses divide the liquid application of sample ware still to be equipped with quantitative subassembly, and quantitative subassembly includes quantitative screw rod 6 and quantitative track groove 7, and quantitative track groove 7 is located on liquid storage pipe 1 is close to the pipe wall 11 of mouth of pipe one end, and quantitative track groove 7 sets up according to actual conditions along the axial of liquid storage pipe 1, and the length of quantitative track groove 7 sets up. Quantitative screw 6 runs through shell 11, ration track groove 7 in proper order and stretches into in the liquid storage tube 1, is equipped with an obstacle 8 on the pole wall of application of sample pole 2, and when application of sample pole 2 removed to obstacle 8 contact quantitative screw 6, application of sample pole 2 stopped moving, accomplished the application of sample process.
The quantitative screw 6 is detachably fixed with the shell 11 and the quantitative track groove 7. Specifically, the quantitative screw 6 is provided with threads, the housing 11 and the quantitative rail groove 7 are respectively provided with threads matched with the screw 6, and the housing 11 is screwed and fixed on the housing 11 and the quantitative rail groove 7 through the threads. Further, the quantitative track groove 7 is also provided with quantitative scales, and before the sample adding step, the quantitative screw 6 can be moved to the corresponding scale position in the quantitative track groove 7 to be screwed down according to the preset sample adding amount. When the sample is added, the piston 21 at one end of the sample adding rod 2 moves in the liquid storage tube 1 until the obstruction 8 on the sample adding rod 2 contacts with the quantitative screw 6. At this time, the sample addition rod 2 cannot move continuously due to the resistance of the quantitative screw 6, which indicates that the sample addition amount is reached, and the sample addition process is ended.
In order to facilitate the quantitative screw 6 to be better fixed on the housing 11 and the quantitative rail groove 7, a fixing gasket 10 is further arranged, and the quantitative screw 6 sequentially penetrates through the fixing gasket 10, the housing 11 and the quantitative rail groove 7.
Referring to fig. 1, in this embodiment, a disposable tip 5 is sleeved on a nozzle of the sample adding tube 4, the sample adding tube 4 divides the pretreatment liquid into the sample container through the disposable tip 5, and the disposable tip 5 is sleeved on the nozzle of the sample adding tube 4.
In this embodiment, divide liquid injector still to be equipped with and move back rifle head device. After the sample adding is completed, the gun head withdrawing device can remove the disposable gun head 5 from the sample adding tube 4 to prepare for the next sample adding operation. The utility model discloses move back rifle head device including moving back rifle head sleeve 91, moving back rifle head handle 92 and connecting rod 93, move back rifle head sleeve 91 cover and locate on the application of sample pipe 4, move back rifle head sleeve 91 and move back rifle head handle 92 and pass through connecting rod 93 and link to each other.
The guide groove 13 is arranged along the axial direction of the shell 11, and the length of the guide groove 13 is not required and is designed according to the actual situation. One end of the gun head withdrawing handle 92 penetrates through the guide groove 13 and is connected with the connecting rod 93.
Referring to fig. 1, the handle 92 for withdrawing the gun head can move along the length direction of the guide groove 13, and when the disposable gun head 5 needs to be removed after the sample adding step is completed, the handle 92 for withdrawing the gun head only needs to move along the guide groove 13 to the direction in which the disposable gun head 5 is removed, and fig. 1 exemplarily shows the moving direction of the handle 92 for withdrawing the gun head.
The following is the working principle of the liquid separation sample injector provided by the embodiment of the present invention is further explained for better understanding of the technical solution of the present invention.
Filling in stock solution pipe 1 sufficient pretreatment fluid, remove quantitative screw 6 and fix to predetermined scale department and screw up on quantitative track groove 7, the palm holds in succession and divides liquid application of sample ware, press application of sample pole handle 22, check valve 41 opens, check valve 31 closes, application of sample pole 2 moves along stock solution pipe 1's axial direction in stock solution pipe 1, liquid pressurized entering in stock solution pipe 1 adds in appearance pipe 4, flow direction disposable rifle head 5, and then add and carry out the application of sample operation in the sample container, until 8 contact quantitative screw 6 of obstacle on application of sample pole 2, the explanation has arrived predetermined application of sample volume, application of sample pole 2 stops to remove, application of sample operation ends.
Then, the sample suction operation is performed into the liquid storage tube 1. The pressure to the sample adding handle 22 is removed, the one-way valve 31 is opened, the one-way valve 41 is closed, the sample adding rod 2 is restored to the original position under the action of the elastic component 12, the liquid is filled in the liquid storage tube 1 again, and the sample sucking process is completed.
And after the sample adding process is finished, carrying out gun head withdrawing operation. And pressing a gun head withdrawing handle 92 in the direction of separating the disposable gun head 5, extruding the disposable gun head 5 to be sleeved on the pipe orifice of the sample adding pipe 4 by a gun head withdrawing sleeve 91 connected with the gun head withdrawing 92 until the disposable gun head 5 is separated, finishing the operation of withdrawing the gun head, and completing a round of liquid separating and sample adding process.
To sum up, the utility model discloses technical scheme's branch liquid application of sample ware has simplified the flow of carrying out the preliminary treatment liquid application of sample to the sample in the biosafety cabinet, has reduced because of the cross contamination that the operation brought, has realized continuous application of sample, very big improvement work efficiency, controllable application of sample volume function can be operated different application of sample volumes between the different samples, and simple structure, light and handy, can carry out hand-held application of sample, provides the basis for accurate application of sample in the biosafety cabinet. Certainly, the utility model discloses technical scheme's branch liquid application of sample ware still can use outside the biosafety cabinet, for example partial shipment and the application of sample of small volume liquid.
The foregoing has described in detail preferred embodiments of the present invention. It should be understood that numerous modifications and variations can be devised by those skilled in the art in light of the teachings of the present invention without undue experimentation. Therefore, the technical solutions that can be obtained by a person skilled in the art through logic analysis, reasoning or limited experiments based on the prior art according to the concepts of the present invention should be within the scope of protection defined by the claims.

Claims (10)

1. A dispensing applicator for use in a biosafety cabinet, comprising:
the liquid storage pipe is used for storing the pretreatment liquid;
one end of the sample adding rod is provided with a sample adding piston matched with the liquid storage tube, and one end of the sample adding rod, which is provided with the sample adding piston, moves in the sample adding tube;
the pipette is communicated with the liquid storage pipe and samples are added into the liquid storage pipe;
and the sample adding pipe is communicated with the liquid storage pipe, and the pretreatment liquid in the liquid storage pipe is added into the specimen container.
2. The sample separating and adding device of claim 1, further comprising a housing, wherein the reservoir tube is located in the housing, and the sample adding rod, the pipette and the sample adding tube all penetrate through the housing.
3. The sample applicator according to claim 2, wherein an elastic member is provided in the housing, and one end of the sample application piston provided on the sample application rod penetrates the housing and the elastic member in sequence and extends into the liquid storage tube.
4. The sample applicator according to claim 2, further comprising a quantitative component, wherein the quantitative component comprises a quantitative screw and a quantitative track groove, the quantitative track groove is disposed on the wall of the liquid storage tube near the end of the tube opening, the quantitative track groove is disposed along the axial direction of the liquid storage tube, the quantitative screw sequentially penetrates through the housing and the quantitative track groove and extends into the liquid storage tube, a stopper is disposed on the wall of the sample application rod, and the sample application rod stops moving when the stopper contacts the quantitative screw.
5. The sample splitter and injector as set forth in claim 4, wherein said quantitative screw is screwed into said housing and said quantitative rail groove.
6. The sample splitter and injector as set forth in claim 5, wherein said dosing assembly further comprises a fixed washer, and said dosing screw penetrates said fixed washer, said housing and said dosing track groove in this order.
7. The liquid-separating sample injector according to claim 2, further comprising a gun head withdrawing device, wherein the gun head withdrawing device comprises a gun head withdrawing sleeve, a gun head withdrawing handle and a connecting rod, the gun head withdrawing sleeve is sleeved on the tube wall of the sample injection tube, and the gun head withdrawing sleeve is connected with the gun head withdrawing handle through the connecting rod.
8. The sample splitter and injector as set forth in claim 7, wherein a guide groove is provided in the axial direction of the housing, and the tip withdrawing handle extends through the guide groove and is connected to the connecting rod.
9. The sample splitter and injector according to claim 1, wherein the nozzle of the sample injection tube is sleeved with a disposable tip, and the sample injection tube injects the pretreatment liquid into the sample container through the disposable tip.
10. The sample separating and adding device according to claim 1, wherein the pipette and the sample adding tube are provided with one-way valves.
CN201920767833.9U 2019-05-24 2019-05-24 Liquid separation sample injector Active CN210115079U (en)

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CN210115079U true CN210115079U (en) 2020-02-28

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110075938A (en) * 2019-05-24 2019-08-02 上海市第五人民医院 A kind of liquid separation sample injector
CN113188867A (en) * 2021-04-29 2021-07-30 河南科技大学第一附属医院 Medical science inspection is with phlegm sample preprocessing device
CN113203611A (en) * 2021-04-29 2021-08-03 河南科技大学第一附属医院 Clinical laboratory is with getting phlegm cup and phlegm sample preprocessing device

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110075938A (en) * 2019-05-24 2019-08-02 上海市第五人民医院 A kind of liquid separation sample injector
CN113188867A (en) * 2021-04-29 2021-07-30 河南科技大学第一附属医院 Medical science inspection is with phlegm sample preprocessing device
CN113203611A (en) * 2021-04-29 2021-08-03 河南科技大学第一附属医院 Clinical laboratory is with getting phlegm cup and phlegm sample preprocessing device
CN113203611B (en) * 2021-04-29 2022-11-04 河南科技大学第一附属医院 Clinical laboratory is with getting phlegm cup and phlegm sample preprocessing device
CN113188867B (en) * 2021-04-29 2022-11-04 河南科技大学第一附属医院 Medical science inspection is with phlegm sample preprocessing device

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