CN210058094U - Electric micro antigen emulsifying device - Google Patents
Electric micro antigen emulsifying device Download PDFInfo
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- CN210058094U CN210058094U CN201920236151.5U CN201920236151U CN210058094U CN 210058094 U CN210058094 U CN 210058094U CN 201920236151 U CN201920236151 U CN 201920236151U CN 210058094 U CN210058094 U CN 210058094U
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Abstract
The utility model relates to the field of material emulsification, in particular to an electric miniature antigen emulsifying device, which comprises a base, wherein an electric drive assembly, a first piston push-pull piece and a second piston push-pull piece are arranged on the base, and a cavity of the first piston push-pull piece is communicated with a cavity of the second piston push-pull piece through a pipe fitting; the piston of the first piston push-pull piece is connected with the electric drive assembly through a connecting piece; the pipe fitting is detachably connected with the cavity of the first piston push-pull piece and the cavity of the second piston push-pull piece. Use the utility model discloses a during antigen emulsification device, easy operation can realize preventing the loss of antigen, need not to utilize ultrasonication appearance, the complete purpose of antigen emulsification to under the condition of realizing antigen emulsification, can effectively avoid the adverse effect that grinding method, ultrasonic method and vortex method among the prior art caused. The utility model discloses also showing and improving emulsification efficiency and degree of automation, reducing the antigen loss, being fit for the emulsification operation of a large amount of antigens.
Description
Technical Field
The utility model relates to a material emulsification field, more specifically relates to an electronic miniature antigen emulsification device.
Background
Emulsification is the effect of one liquid being dispersed uniformly as very fine droplets in another liquid that is immiscible with each other. Emulsification is a liquid-liquid interface phenomenon, in which two immiscible liquids, such as oil and water, are separated into two layers in a container, with less dense oil on the upper layer and more dense water on the lower layer. If a suitable surfactant is added, the oil is dispersed in water under vigorous stirring to form an emulsion, a process called emulsification. The adjuvant most commonly used in animal experiments is Freund's adjuvant at present. Before immunizing animal, Freund's adjuvant and antigen are mixed in certain proportion. The volume ratio of adjuvant to antigen is typically 1: 1 are prepared as "water-in-oil" emulsions.
In order to ensure that the immunologic adjuvant can be well fused with the antigen, the immunologic adjuvant and the antigen need to be completely emulsified and fused, the traditional antigen emulsification methods comprise a grinding method, an injector method, a mixing method and an ultrasonic method, the grinding method needs a large amount of time, and meanwhile, a large amount of emulsion is adhered to the wall of a grinding bowl, so that the antigen loss is large; the syringe method and the mixing method are time-consuming and labor-consuming, and the liquid medicine is easy to leak; the ultrasound method is easily destructive to the antigen, and none of these conventional methods is suitable for experimenters to rapidly formulate reagents.
SUMMERY OF THE UTILITY MODEL
To the technical problem who exists among the prior art, the utility model aims to provide an electronic miniature antigen emulsification device utilizes the electronic emulsification antigen of the device, is showing and is improving emulsification efficiency and degree of automation, reduces the antigen loss, is fit for the emulsification operation of a large amount of antigens.
In order to achieve the purpose, the utility model is realized by the following technical scheme:
the utility model provides an electric micro antigen emulsifying device, which comprises a base, wherein an electric drive assembly, a first piston push-pull piece and a second piston push-pull piece are arranged on the base, and a cavity of the first piston push-pull piece is communicated with a cavity of the second piston push-pull piece through a pipe fitting; the piston of the first piston push-pull piece is connected with the electric drive assembly through a connecting piece; the pipe fitting is detachably connected with the cavity of the first piston push-pull piece and the cavity of the second piston push-pull piece.
Further, the electric drive assembly includes a motor and a control switch electrically connected to the motor.
Furthermore, a speed regulator is arranged on the base and electrically connected with the control switch.
Furthermore, a timer is arranged on the base and electrically connected with the control switch.
Furthermore, the pipe fitting is a linear pipeline, a consistency sensor is arranged in the pipe fitting, and the consistency sensor is electrically connected with the control switch.
Still further, the device is also provided with an indicator light, which is electrically connected with the consistency sensor.
Further, the pipe is provided with a window made of transparent materials.
Compared with the prior art, the beneficial effects of the utility model reside in that:
(1) the utility model provides a pair of electronic miniature antigen emulsification device is showing and is improving emulsification efficiency and degree of automation, reduces the antigen loss, is fit for the emulsification operation of a large amount of antigens.
(2) Use the utility model discloses a during antigen emulsification device, easy operation can realize preventing the loss of antigen, need not to utilize ultrasonication appearance, the complete purpose of antigen emulsification to under the condition of realizing antigen emulsification, can effectively avoid the adverse effect that grinding method, ultrasonic method and vortex method among the prior art caused.
Drawings
Fig. 1 is a schematic structural diagram of the electric micro-emulsified antigen device of the present invention.
Detailed Description
The following examples are presented to illustrate certain embodiments of the invention and should not be construed as limiting the scope of the invention. The present disclosure may be modified from materials, methods, and reaction conditions at the same time, and all such modifications are intended to be within the spirit and scope of the present disclosure.
In the description of the present invention, it is to be understood that the terms indicating orientation or positional relationship are based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplification of description, and do not indicate or imply that the equipment or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
Example 1
An electric micro antigen emulsifying device comprises a base 1, wherein an electric drive assembly 2 is arranged on the base 1, the electric drive assembly 2 specifically comprises a motor 201 and a control switch 202 electrically connected with the motor, and the motor is powered by a mains supply 220V; the base 1 is also provided with a first piston push-pull piece 3 and a second piston push-pull piece 4, the two piston push-pull pieces have the functions of extracting liquid and containing the liquid, and the two piston push-pull pieces in the embodiment can be replaced by a syringe. The cavity of the first piston push-pull piece 3 is communicated with the cavity of the second piston push-pull piece 4 through a pipe fitting 5, and the pipe fitting 5 is detachably connected with the cavity of the first piston push-pull piece 3 and the cavity of the second piston push-pull piece 4; in order to conveniently observe the emulsification effect, the pipe fitting 5 is a transparent silicone tube in the embodiment. The piston 301 of the first piston push-pull member is connected to the crankshaft of the motor 201 through a connecting member 6, and specifically, the connecting member 6 is a connecting rod connected to the crankshaft.
In this embodiment, the non-piston ends of the first piston pushing and pulling member 3 and the second piston pushing and pulling member 4 have external threads, the two ends of the pipe fitting 5 both have internal threads, and the first piston pushing and pulling member 3 and the second piston pushing and pulling member 4 are detachably connected with the pipe fitting 5 respectively by adopting a mode that the external threads are connected with the internal threads.
A speed regulator 7 and a timer 8 are also mounted on the base 1, and the speed regulator 7 and the timer 8 are both electrically connected with a control switch 202.
In another embodiment, the pipe 5 is a linear pipe, which can make the solution flow more smoothly between the cavity of the first piston push-pull member 3, the pipe 5, and the cavity of the second piston push-pull member 4.
Since the most important index in the emulsification process is the consistency, when the emulsification is complete, the consistency is greatly improved, therefore, a consistency sensor is arranged in the pipe 5 and electrically connected with the control switch 202, and the completeness of the emulsification can be known by monitoring the consistency of the antigen solution in the emulsification process. The accessible preset consistency threshold value, when the consistency of solution when the consistency sensor surveys surpasses this threshold value, control switch makes agitator motor stop work, and the emulsification is accomplished to realize automatic control, need not personnel and observe and operate.
In another embodiment, the device of the present invention is further provided with an indicator light, said indicator light being electrically connected to said consistency sensor for indicating a change in the consistency of the solution.
The working principle is as follows:
firstly, the rotating speed and the emulsifying time of the curved track during antigen emulsification are set through a speed regulator 7 and a timer 8, then a certain amount of antigen and Freund's adjuvant are extracted by using a first piston push-pull piece 3 and a second piston push-pull piece 4 (both the two piston push-pull pieces can be injectors), and after the reagent is extracted, the non-piston ends of the first piston push-pull piece 3 and the second piston push-pull piece 4 are connected by using a transparent silicone tube 5. Starting the motor 201, the motor crankshaft rotates, the crankshaft drives the piston of the first piston push-pull piece to start reciprocating motion, and the second piston push-pull rod 4 also carries out reciprocating motion, so that the solution flows among the cavity of the first piston push-pull piece 3, the pipe fitting 5 and the cavity of the second piston push-pull piece 4, when the consistency of the mixed solution reaches a set consistency threshold value, the control switch stops the stirring motor, the emulsification is completed, automatic control is realized, and no personnel are required to observe and operate.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be within the technical scope of the present invention, and the technical solution and the inventive concept of the present invention are equivalent to or changed according to the present invention, and all those are included in the scope of the present invention.
Claims (7)
1. An electric miniature antigen emulsifying device comprises a base (1), and is characterized in that an electric drive assembly (2), a first piston push-pull piece (3) and a second piston push-pull piece (4) are arranged on the base (1), and a cavity of the first piston push-pull piece (3) is communicated with a cavity of the second piston push-pull piece (4) through a pipe fitting (5); the piston (301) of the first piston push-pull piece is connected with the electric drive assembly (2) through a connecting piece (6); the pipe fitting (5) is detachably connected with the cavity of the first piston push-pull piece (3) and the cavity of the second piston push-pull piece (4).
2. An electric micro antigen emulsifying device according to claim 1, characterized in that the electric driving assembly (2) comprises a motor (201) and a control switch (202) electrically connected to the motor.
3. The electric miniature antigen emulsifying device of claim 2, wherein a speed regulator (7) is further arranged on the base (1), and the speed regulator (7) is electrically connected with the control switch (202).
4. The electric miniature antigen emulsifying device of claim 2, wherein a timer (8) is further disposed on the base, and the timer (8) is electrically connected to the control switch (202).
5. The electric micro antigen emulsifying device of claim 2, wherein the pipe (5) is a linear pipe, and a consistency sensor is arranged in the pipe (5), and the consistency sensor is electrically connected with the control switch (202).
6. The electric micro antigen emulsifying device of claim 5, wherein an indicator light is further provided, and the indicator light is electrically connected to the consistency sensor.
7. The electric miniature antigen emulsifying device of claim 1, wherein the tube (5) has a window made of transparent material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920236151.5U CN210058094U (en) | 2019-02-25 | 2019-02-25 | Electric micro antigen emulsifying device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920236151.5U CN210058094U (en) | 2019-02-25 | 2019-02-25 | Electric micro antigen emulsifying device |
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| Publication Number | Publication Date |
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| CN210058094U true CN210058094U (en) | 2020-02-14 |
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| CN201920236151.5U Active CN210058094U (en) | 2019-02-25 | 2019-02-25 | Electric micro antigen emulsifying device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111249935A (en) * | 2020-03-04 | 2020-06-09 | 南京巴傲得生物科技有限公司 | Full-automatic emulsification equipment suitable for Freund's adjuvant |
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2019
- 2019-02-25 CN CN201920236151.5U patent/CN210058094U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111249935A (en) * | 2020-03-04 | 2020-06-09 | 南京巴傲得生物科技有限公司 | Full-automatic emulsification equipment suitable for Freund's adjuvant |
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Denomination of utility model: An electric miniature antigen emulsification device Effective date of registration: 20230410 Granted publication date: 20200214 Pledgee: Bank of China Limited by Share Ltd. Wuhan Wuchang branch Pledgor: WUHAN YUANGU BIOTECHNOLOGY CO.,LTD. Registration number: Y2023980037582 |