CN209890612U - Full-automatic autologous adipose tissue conversion device - Google Patents
Full-automatic autologous adipose tissue conversion device Download PDFInfo
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- CN209890612U CN209890612U CN201920515900.8U CN201920515900U CN209890612U CN 209890612 U CN209890612 U CN 209890612U CN 201920515900 U CN201920515900 U CN 201920515900U CN 209890612 U CN209890612 U CN 209890612U
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- piston
- air cylinder
- adipose tissue
- conversion device
- fat
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- 210000000577 adipose tissue Anatomy 0.000 title claims abstract description 28
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 28
- 239000002245 particle Substances 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 210000001503 joint Anatomy 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 description 8
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 4
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 210000002744 extracellular matrix Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000000130 stem cell Anatomy 0.000 description 3
- 210000001789 adipocyte Anatomy 0.000 description 2
- 210000002889 endothelial cell Anatomy 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000009815 adipogenic differentiation Effects 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000000701 coagulant Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 210000003668 pericyte Anatomy 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
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Abstract
The utility model discloses a full-automatic autologous adipose tissue conversion equipment, including the first inflator piston subassembly, fat cutting crossover sub and the second inflator piston subassembly that set gradually, fat cutting crossover sub's both ends respectively with first inflator piston subassembly and the detachable connection of second inflator piston subassembly, fat cutting crossover sub includes the tubulose joint body and sets up this internal fibrous filter screen of thick in the filtration adipose tissue that is arranged in of tubulose joint, the two sides of filter screen all set up to the sword form of being convenient for cut fat particle lump. The utility model discloses a full-automatic autologous adipose tissue conversion equipment, conversion efficiency is good, and conversion efficiency is fast.
Description
Technical Field
The utility model relates to the technical field of medical equipment, in particular to full-automatic autologous adipose tissue conversion equipment.
Background
The adipose tissue is mechanically converted and deoiled to obtain an injectable gel-like concentrated adipose tissue rich in vascular matrix components (SVF) and extracellular matrix (ECM). Adipose stem cells (ADSCs) in Stromal Vascular Fraction (SVF) account for about 10%, and in addition, adipose precursor cells, endothelial progenitor cells, endothelial cells, pericytes, smooth muscle cells, fibroblasts, hematopoietic stem cells, leukocytes, erythrocytes, T lymphocytes, B lymphocytes, monocytes, macrophages, and the like. In the prior art, the conversion process is manually operated, the conversion effect is poor, the conversion efficiency is low, and manpower is consumed.
Therefore, there is a need for improvement of the prior art to solve the above technical problems.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims at providing a full-automatic autologous adipose tissue conversion device, conversion effect is good, and conversion efficiency is fast. The method is realized by the following technical scheme:
the utility model discloses a full-automatic autologous adipose tissue conversion equipment, including the first inflator piston subassembly, fat cutting crossover sub and the second inflator piston subassembly that set gradually, fat cutting crossover sub's both ends respectively with first inflator piston subassembly and the detachable connection of second inflator piston subassembly, fat cutting crossover sub includes the tubulose joint body and sets up this internal fibrous filter screen of thick in the fat tissue that is arranged in filtering of tubulose joint, the two sides of filter screen all set up to the sword form of being convenient for cut fat particle piece.
In a preferred technical scheme, the first cylinder piston assembly comprises a first cylinder and a first piston axially and slidably connected to the first cylinder, and the second cylinder piston assembly comprises a second cylinder and a second piston axially and slidably connected to the second cylinder; and the piston driver is used for driving the first piston or/and the second piston to reciprocate axially.
In the preferred technical scheme, a first supporting and limiting frame used for supporting and axially limiting the first air cylinder is arranged below the first air cylinder, and a second supporting and limiting frame used for supporting and axially limiting the second air cylinder is arranged below the second air cylinder.
In a preferable technical scheme, the end of the first air cylinder is provided with a first connecting part which is in butt joint with the end of the tubular joint body, the first connecting part comprises a first inner tube communicated with the inside of the first air cylinder and a first outer tube concentrically arranged with the first inner tube, a first inner thread is arranged on the inner diameter of the first outer tube, and the end of the tubular joint body is provided with a joint outer thread matched with the first inner thread.
In a preferred technical scheme, the inner diameter of the end part of the tubular joint body is set to be a conical structure matched with the outer diameter of the first inner pipe.
In a preferred technical scheme, the first gas cylinder piston assembly, the fat cutting adapter and the second gas cylinder piston assembly are at least correspondingly arranged in two groups, and the piston drive comprises piston connecting pieces connected with all the first pistons and a piston drive body acting on the piston connecting pieces.
In the preferred technical scheme, the piston driving body adopts a servo motor module or a servo electric push rod.
The utility model has the advantages that: the utility model discloses a full-automatic autologous adipose tissue conversion device, after a first air cylinder piston component and a second air cylinder piston component are injected repeatedly, adipose tissues move between a first air cylinder and a second air cylinder repeatedly through a fat cutting conversion joint; when fat tissues pass through the filter screen, not only can thicker fibers be filtered, but also the cutting edge shape on the filter screen can cut fat particle agglomerates, so that the removed diameter is reduced, and the tissues are finer; furthermore, the process destroys mature fat cells with large volume, so that a large amount of oil drops are released after the mature fat cells are destroyed and added into the fat which is treated by mechanical force, because the oil drops are coagulant agents for activating flocculation, the stability of charged particles is reduced, the emulsion is further separated from the oil, and the granular fat tissue is promoted to be transformed into gel-like concentrated fat tissue. The cell factor and fat stem cell in the gel-like concentrated fat tissue are higher than those in common fat tissue. And the extracellular matrix (ECM) structure in the adipose tissue is effectively retained, a 'scaffold' is provided for the regeneration of blood vessels after the adipose tissue transplantation, the scaffold provides adhesion for the infiltration of cells after the ADSCs transplantation, is beneficial to the subsequent revascularization and adipogenic differentiation of the cells, protects important cells from being attacked by immune cells, and thus improves the survival rate of the transplanted adipose tissue.
Other advantageous effects of the present invention will be further described with reference to the following embodiments.
Drawings
The invention will be further described with reference to the following figures and examples:
FIG. 1 is a schematic side view of the present invention;
FIG. 2 is a top view of FIG. 1;
FIG. 3 is a cross-sectional view taken along line F-F of FIG. 2;
FIG. 4 is an enlarged view of a portion of FIG. 3 at a;
FIG. 5 is a front view of a fat cutting adaptor;
FIG. 6 is a cross-sectional view taken along line D-D of FIG. 5;
FIG. 7 is a schematic view of an axial structure of the filter screen;
FIG. 8 is a schematic view of the construction of the first cartridge;
FIG. 9 is a front view of FIG. 8;
FIG. 10 is a cross-sectional view taken along line A-A of FIG. 9;
FIG. 11 is a schematic view of the first piston;
fig. 12 is a schematic view of the structure of the piston connecting member.
Detailed Description
As shown in the figure: the full-automatic autologous adipose tissue conversion device in the embodiment comprises a first air cylinder piston assembly, a fat cutting conversion joint 4 and a second air cylinder piston assembly which are sequentially arranged, wherein two ends of the fat cutting conversion joint 4 are detachably connected with the first air cylinder piston assembly and the second air cylinder piston assembly respectively, the fat cutting conversion joint comprises a tubular joint body 4-1 and a filter screen 4-2 which is arranged in the tubular joint body 4-1 and used for filtering thick and thick fibers in adipose tissues, and two sides of the filter screen are both provided with blade shapes 4-21 convenient for cutting fat particle lumps.
In this embodiment, the first cylinder piston assembly comprises a first cylinder 5 and a first piston 7 axially slidably connected to the first cylinder, and the second cylinder piston assembly comprises a second cylinder 3 and a second piston 1 axially slidably connected to the second cylinder; and a piston drive for driving the first piston 7 or/and the second piston 1 to reciprocate axially. The piston driving may drive only the first piston 7 as shown in fig. 1, and when the first piston 7 advances, while the adipose tissues are driven to move from the first cylinder 5 into the second cylinder 3, the air pressures in the first cylinder 5, the tubular joint body 4-1 and the second cylinder 3 are increased to be higher than the external atmospheric pressure, and the air pressure difference pushes the second piston 1 to retreat; when the first piston 7 retreats, the fat tissue is driven to transfer from the second air cylinder 3 into the first air cylinder 5, and simultaneously, the air pressure in the first air cylinder 5, the tubular joint body 4-1 and the second air cylinder 3 is reduced to be lower than the external atmospheric pressure, and the air pressure difference pushes the second piston 1 to advance. It is of course also possible to drive the first piston 7 and the second piston 1 to and fro simultaneously with different drives, respectively.
In this embodiment, a first supporting and limiting frame 6 for supporting and axially limiting the first air cylinder 5 is arranged below the first air cylinder 5, and a second supporting and limiting frame 2 for supporting and axially limiting the second air cylinder 3 is arranged below the second air cylinder 3. The end part of the first air cylinder body 5-2 can be provided with an air cylinder flange 5-3, and the first supporting and limiting frame 6 is provided with a groove for axial fibers of the air cylinder flange 5-3, but other existing limiting structures can also be adopted. The first air cylinder 5 and the second air cylinder 3 are axially limited, and the first air cylinder 5 and the second air cylinder 3 are prevented from moving along with the axial movement when the first piston 7 or/and the second piston 1 is driven.
In this embodiment, a first connecting portion 5-1 is disposed at an end of the first cylinder body 5-2 and is abutted to an end of the tubular joint body 4-1, the first connecting portion includes a first inner tube 5-11 communicated with the inside of the first cylinder and a first outer tube 5-12 concentrically disposed with the first inner tube 5-11, a first inner thread is disposed on an inner diameter of the first outer tube 5-12, and a joint outer thread 4-3 matched with the first inner thread is disposed at an end of the tubular joint body 4-1. When in connection or disassembly, the external thread 4-3 is only required to be inserted between the first inner pipe 5-11 and the first outer pipe 5-12 to be rotated, so that the connection is fast and reliable.
In this embodiment, the inner diameter of the end of the tubular fitting body 4-1 is configured as a tapered structure that matches the outer diameter of the first inner tube 5-11. The conical structure ensures good sealing performance of the joint while ensuring quick and smooth connection.
In this embodiment, the first cylinder piston assembly, the fat cutting adaptor 4 and the second cylinder piston assembly are at least arranged in two corresponding sets, and the piston driver comprises piston connectors 8 connected with all the first pistons 7 and a piston driver body 9 acting on the piston connectors. As shown in fig. 1, when four sets are provided, the piston connecting members 8 are connected to 4 first pistons 7 at the same time, and the number of the piston driving bodies 9 is two, and of course, the number of the piston driving bodies 9 depends on the length of the piston connecting members 8. The first piston 7 comprises a first piston head 7-1, a first piston shaft 7-2 and a piston connecting part 7-3, wherein the first piston head 7-1 is connected with the first cylinder body 5-2 in an axial sliding and sealing mode, the piston connecting part 7-3 is used for being connected with the piston connecting part 8, the main body part 8-1 of the piston connecting part 8 is fixedly connected with the output end of the piston driving body 9, the convex edge 8-2 of the piston connecting part 8 is clamped into a groove below the piston connecting part 7-3, and the end part of the piston connecting part 7-3 is clamped into the groove 8-2 of the piston connecting part. A small amount of pistons are used for driving the body 9 and a large amount of first pistons 7, so that the efficiency is improved, and the energy is saved.
In this embodiment, the piston driving body 9 is a servo motor module or a servo electric push rod. Certainly, the piston driving body 9 can also be driven by other straight lines such as an air cylinder, a hydraulic cylinder and the like, the driving speed can be accurately controlled by adopting a servo motor module or a servo electric push rod, the movement speed of adipose tissues is generally required to be 10 ml/s, and the whole conversion process can be completed by injecting for about 1 min; the motion is too slow, the efficiency is low, and the excessive damage of the adipose tissues is easily caused by the too fast motion.
It should be noted that, in the above embodiments, the first piston assembly and the second piston assembly are symmetrically arranged, and the structures are similar, and after the first piston assembly is introduced, the corresponding structure of the second piston assembly is not described again, and those skilled in the art can implement the corresponding technology. And the first and second are for descriptive convenience only and do not specifically limit the scope of the claims.
Finally, although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the present invention can be modified or replaced by other means without departing from the spirit and scope of the present invention, which should be construed as limited only by the appended claims.
Claims (7)
1. The utility model provides a full-automatic autologous adipose tissue conversion equipment which characterized in that: including the first inflator piston subassembly, fat cutting crossover sub and the second inflator piston subassembly that set gradually, fat cutting crossover sub's both ends respectively with first inflator piston subassembly and the detachable connection of second inflator piston subassembly, fat cutting crossover sub includes the tubulose joint body and sets up this internal fibrous filter screen of thick in being used for filtering adipose tissue at the tubulose joint, the two sides of filter screen all set up to the sword form of being convenient for cut fat particle piece of mass.
2. The fully automatic autologous adipose tissue conversion device according to claim 1, wherein: the first air cylinder piston assembly comprises a first air cylinder and a first piston axially and slidably connected to the first air cylinder, and the second air cylinder piston assembly comprises a second air cylinder and a second piston axially and slidably connected to the second air cylinder; and the piston driver is used for driving the first piston or/and the second piston to reciprocate axially.
3. The fully automatic autologous adipose tissue conversion device according to claim 2, wherein: a first supporting and limiting frame used for supporting and axially limiting the first air cylinder is arranged below the first air cylinder, and a second supporting and limiting frame used for supporting and axially limiting the second air cylinder is arranged below the second air cylinder.
4. The fully automatic autologous adipose tissue conversion device according to claim 2, wherein: the end of the first air cylinder is provided with a first connecting part which is in butt joint with the end of the tubular joint body, the first connecting part comprises a first inner pipe communicated with the inside of the first air cylinder and a first outer pipe concentrically arranged with the first inner pipe, a first inner thread is arranged on the inner diameter of the first outer pipe, and a joint outer thread matched with the first inner thread is arranged at the end of the tubular joint body.
5. The fully automatic autologous adipose tissue conversion device according to claim 4, wherein: the inner diameter of the end part of the tubular joint body is set to be a conical structure matched with the outer diameter of the first inner pipe.
6. The fully automatic autologous adipose tissue conversion device according to claim 2, wherein: the first gas cylinder piston assembly, the fat cutting adapter and the second gas cylinder piston assembly are at least correspondingly provided with two groups, and the piston drive comprises piston connecting pieces connected with all the first pistons and a piston drive body acting on the piston connecting pieces.
7. The fully automatic autologous adipose tissue conversion device according to claim 2, wherein: the piston driving body adopts a servo motor module or a servo electric push rod.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920515900.8U CN209890612U (en) | 2019-04-15 | 2019-04-15 | Full-automatic autologous adipose tissue conversion device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920515900.8U CN209890612U (en) | 2019-04-15 | 2019-04-15 | Full-automatic autologous adipose tissue conversion device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209890612U true CN209890612U (en) | 2020-01-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920515900.8U Expired - Fee Related CN209890612U (en) | 2019-04-15 | 2019-04-15 | Full-automatic autologous adipose tissue conversion device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209890612U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796606A (en) * | 2021-01-20 | 2022-07-29 | 南方医科大学南方医院 | Rigid fat transplantation composite material and preparation method and application thereof |
| CN116240094A (en) * | 2023-05-08 | 2023-06-09 | 北京纳通医疗科技控股有限公司 | Separation device and SVF preparation method |
-
2019
- 2019-04-15 CN CN201920515900.8U patent/CN209890612U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796606A (en) * | 2021-01-20 | 2022-07-29 | 南方医科大学南方医院 | Rigid fat transplantation composite material and preparation method and application thereof |
| CN114796606B (en) * | 2021-01-20 | 2024-03-01 | 南方医科大学南方医院 | Rigid fat transplantation composite material and preparation method and application thereof |
| CN116240094A (en) * | 2023-05-08 | 2023-06-09 | 北京纳通医疗科技控股有限公司 | Separation device and SVF preparation method |
| CN116240094B (en) * | 2023-05-08 | 2023-08-04 | 北京纳通医疗科技控股有限公司 | Separation device and SVF preparation method |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200103 |
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| CF01 | Termination of patent right due to non-payment of annual fee |