CN220467967U - Umbilical cord mesenchymal stem cell extraction and separation device - Google Patents
Umbilical cord mesenchymal stem cell extraction and separation device Download PDFInfo
- Publication number
- CN220467967U CN220467967U CN202321635452.8U CN202321635452U CN220467967U CN 220467967 U CN220467967 U CN 220467967U CN 202321635452 U CN202321635452 U CN 202321635452U CN 220467967 U CN220467967 U CN 220467967U
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- box body
- mesenchymal stem
- umbilical cord
- stem cell
- fixed
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- 238000000926 separation method Methods 0.000 title claims abstract description 58
- 210000003954 umbilical cord Anatomy 0.000 title claims abstract description 30
- 210000002901 mesenchymal stem cell Anatomy 0.000 title claims abstract description 29
- 238000000605 extraction Methods 0.000 title claims abstract description 24
- 210000001503 joint Anatomy 0.000 claims abstract description 30
- 230000007246 mechanism Effects 0.000 claims abstract description 15
- 239000012528 membrane Substances 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 9
- 210000004027 cell Anatomy 0.000 abstract description 20
- 239000003292 glue Substances 0.000 abstract description 8
- 235000015110 jellies Nutrition 0.000 description 16
- 239000008274 jelly Substances 0.000 description 16
- 235000012773 waffles Nutrition 0.000 description 4
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 108010082117 matrigel Proteins 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000001644 umbilical artery Anatomy 0.000 description 1
- 210000003606 umbilical vein Anatomy 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses an umbilical mesenchymal stem cell extraction and separation device which comprises a separation box body and a feed inlet, wherein the feed inlet is fixed on the upper side of the separation box body, the feed inlet is in butt joint with a cover plate, a receiving plate is fixed on the inner side of the separation box body, and a driving mechanism is arranged on the outer side of the separation box body. This umbilical cord mesenchymal stem cell draws separator, start first motor and second motor earlier, make cutting roller and connecting roller rotate, place the chinese through the feed inlet in the upside of connecing the flitch, chinese through glue is along connecing the flitch to cutting roller removal, make umbilical cord mesenchymal stem cell draw separator be convenient for carry out even shredding to chinese through glue, rotatory fixed block, make the fixed block drive the connecting pad and break away from the receiver, make chinese through the cell accessible of glue discharge of butt joint groove, make umbilical cord mesenchymal stem cell draw separator be convenient for take out chinese through the cell of glue.
Description
Technical Field
The utility model relates to the technical field of umbilical cord mesenchymal stem cells, in particular to an extraction and separation device for umbilical cord mesenchymal stem cells.
Background
The umbilical cord mesenchymal stem cells are matrigel in umbilical cord tissues, named Wharton's jelly, wrap up 2 umbilical arteries and 1 umbilical vein in the umbilical cord, can protect umbilical cord blood vessels from being mechanically pressed or distorted by external force, have self-replication, multidirectional differentiation, homing property, repair capability and the like, and are easy to obtain the umbilical cord tissues and convenient to obtain by experiments;
according to publication number CN215162605U, the umbilical cord mesenchymal thousand cells extraction and separation device comprises an upper shell with a bottom surface, a lower racing body and an upper cover, wherein the bottom surface of the upper shell is placed on the lower racing body, and the upper cover is covered on the upper shell: the bottom end of the lower shell is provided with an opening and closing door, the upper part of the inner wall of the lower shell is fixedly provided with a symmetrical hanging table, a cell collecting hopper is detachably placed on the hanging table, and the lower part of the collecting hopper is spirally connected with a cell collecting bottle; the bottom surface of the upper shell is V-shaped and parallel to the collecting surface of the collecting hopper, the V-shaped surface is provided with pointed protrusions and leakage holes at intervals, the side wall of the upper shell is provided with a fixing hole, a cross rod penetrates through the hole, one end of the cross rod in the upper body is provided with a downward elbow, the lower end of the quart head is provided with a V-shaped pointed hammer, the surface of the pointed hammer is provided with pointed protrusions, and the pointed hammer can be meshed with the pointed protrusions on the bottom surface of the upper shell in a staggered manner when moving downwards. The utility model has simple structure and convenient operation, and ensures pollution-free thousand cells in the separation and extraction process to the maximum extent;
according to the patent, a worker pulls the manual handle up and down to enable the pointed protrusions on the pointed hammer to be engaged with the pointed protrusions on the bottom surface of the upper shell in a staggered manner, so that the Chinese trabecula gum is broken into blocks.
Disclosure of Invention
The utility model aims to provide an umbilical mesenchymal stem cell extraction and separation device, which is used for solving the problem that the Whatman's jelly is broken by manually pulling a manual handle, so that the frequency of staggered occlusion between a pointed protrusion on a pointed hammer and a pointed protrusion on the bottom surface of an upper shell is different, and the Whatman's jelly is not uniform enough.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides an umbilical cord mesenchymal stem cell draws separator, includes separation box body and feed inlet, the upside of separation box body is fixed with the feed inlet, and the feed inlet is docked with the apron, the inboard of separation box body is fixed with the material receiving plate, and the outside of separation box body is provided with actuating mechanism, actuating mechanism is including first motor and second motor, first motor and second motor are installed in proper order in the outside of separation box body, the separation box body passes through bearing and cutting roller swing joint in the below of material receiving plate, the output shaft and the cutting roller of first motor are fixed mutually, the output shaft and the connecting roller of second motor are fixed mutually.
Preferably, the lower side of the separation box body is provided with an extraction box body mechanism, and the extraction box body mechanism comprises an abutting plate, a receiving box, a fixing plate and a filtering membrane, and the lower side of the separation box body is abutted with the abutting plate.
Preferably, a receiving box is fixed on the lower side of the butt plate, and a fixing plate is fixed on the inner side of the receiving box.
Preferably, a filtering membrane is arranged on the upper side of the fixing plate.
Preferably, the inner side of the material receiving box is fixed with an inclined plate, and a butt joint groove is formed in one side of the inclined plate.
Preferably, the butt joint groove is in butt joint with the connecting pad, and one side of the connecting pad is connected with a fixing block.
Preferably, the fixing block is in butt joint with the receiving box.
Compared with the prior art, the utility model has the beneficial effects that: this umbilical cord mesenchymal stem cell draws separator, start first motor and second motor earlier, make cutting roller and connecting roller rotate, place the chinese through the feed inlet in the upside of connecing the flitch, chinese through glue is along connecing the flitch to cutting roller removal, make umbilical cord mesenchymal stem cell draw separator be convenient for carry out even shredding to chinese through glue, rotatory fixed block, make the fixed block drive the connecting pad and break away from the receiver, make chinese through the cell accessible of glue discharge of butt joint groove, make umbilical cord mesenchymal stem cell draw separator be convenient for take out chinese through the cell of glue.
1. When the umbilical cord mesenchymal stem cell extraction and separation device is used, a first motor and a second motor are started, a power output shaft of the first motor and a power output shaft of the second motor respectively drive a cutting roller and a connecting roller to rotate, a cover plate is lifted, wharton's jelly is placed on the upper side of a material receiving plate through a feed inlet, the cover plate is in butt joint with the feed inlet, and Wharton's jelly moves along the material receiving plate towards the cutting roller, so that the cutting roller can uniformly cut Wharton's jelly, and the umbilical cord mesenchymal stem cell extraction and separation device is convenient for uniformly cutting Wharton's jelly;
2. according to the umbilical cord mesenchymal stem cell extraction and separation device, when the cells of the Wharton's jelly drop to the upper side of the inclined plate through the filtering membrane, the cells of the Wharton's jelly are enabled to flow to the butt joint groove in a concentrated mode, the fixing block is rotated, the fixing block drives the connecting pad to be separated from the material box, the cells of the Wharton's jelly can be discharged through the butt joint groove, and the umbilical cord mesenchymal stem cell extraction and separation device is convenient to take out the cells of the Wharton's jelly.
Drawings
FIG. 1 is a schematic elevational view of the present utility model;
FIG. 2 is a schematic elevational cross-sectional structure of the present utility model;
fig. 3 is a schematic view of a right-side cross-sectional structure of the present utility model.
In the figure: 1. separating the box body; 11. a feed inlet; 12. a cover plate; 13. a receiving plate; 2. a driving mechanism; 21. a first motor; 22. a second motor; 3. a cutting roller; 31. a connecting roller; 4. a cartridge extraction mechanism; 41. an abutting plate; 42. a receiving box; 43. a fixing plate; 44. a filtering membrane; 5. a sloping plate; 6. a butt joint groove; 7. a connection pad; 8. and a fixed block.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, the present utility model provides a technical solution: the utility model provides an umbilical cord mesenchymal stem cell draws separator, including separation box body 1 and feed inlet 11, the upside of separation box body 1 is fixed with feed inlet 11, and feed inlet 11 and apron 12 butt joint, the inboard of separation box body 1 is fixed with connects flitch 13, and the outside of separation box body 1 is provided with actuating mechanism 2, actuating mechanism 2 is including first motor 21 and second motor 22, first motor 21 and second motor 22 are installed in proper order in the outside of separation box body 1, separation box body 1 passes through bearing and cutting roller 3 swing joint in the below of connecing flitch 13, the output shaft of first motor 21 is fixed with cutting roller 3 mutually, the output shaft of second motor 22 is fixed with connecting roller 31 mutually, the downside of separation box body 1 is provided with and draws box body mechanism 4, and draw box body mechanism 4 including butt joint 41, connect box 42, fixed plate 43 and filtration membrane 44, the downside of separation box body 1 and butt joint 41 are fixed with butt joint box 42, and the inboard of connecting box body 1 is fixed with motor 43, the fixed plate 43 is fixed with the output shaft of first motor and fixed plate 43 is the opposite direction of cutting roller 3, the output shaft of second motor 43 is fixed with cutting roller 3, the opposite direction of blade 3 is connected with cutting roller 3.
During the implementation, when extracting separator uses, start first motor 21 and second motor 22 earlier, make the output shaft of first motor 21 and the output shaft of second motor 22 drive cutting roller 3 and connecting roller 31 respectively and rotate, the output shaft through first motor 21 and the output shaft rotation direction of second motor 22 are opposite, make cutting roller 3 and connecting roller 31 counter-rotating, lift apron 12 again, make apron 12 break away from feed inlet 11, place the waffle rubber in the upside of connecting plate 13 through feed inlet 11, dock apron 12 and feed inlet 11 again, be the slope fixed through connecting plate 13, make waffle rubber follow cutting roller 3 and remove, be fixed with the blade of field word lattice structure through the outside of cutting roller 3, and the blade of cutting roller 3 is laminated with connecting roller 31 mutually, make cutting roller 3 can cut up waffle rubber evenly, the cell back of waffle rubber is filtered through filtration membrane 44, rotatory receiver 42 is taken out, make the receiver 42 drive the opposite direction of rotation of receiver 42 place the upper side at connecting plate 13 at the connecting plate 13, make the separation device is cut up to the filter membrane 1 with the filter membrane 31, make the separation body of cut-up body 1 and the filter membrane 1, make the separation device is directly carried out to cut up the separation body 1 and the filter membrane 1 is placed at the filter membrane 3, the separation device is directly to the side of the separation device is convenient for the filter membrane 1, the separation device is placed at the side of the filter membrane 1 is separated with the filter membrane 1 through the filter membrane 1, the separation device is convenient for the separation device is separated to the filter 1 to take down.
The inboard of receiving the magazine 42 is fixed with swash plate 5, and connects the magazine 42 to offer butt joint groove 6 in one side of swash plate 5, butt joint groove 6 dock with connecting pad 7, and one side of connecting pad 7 is connected with fixed block 8, and fixed block 8 dock with receiving the magazine 42, and connecting pad 7 adopts the rubber material, and connecting pad 7 extrudees mutually with butt joint groove 6, and fixed block 8 and receiving the magazine 42 become threaded connection.
In specific implementation, when the cells of the Wharton's jelly drop to the upper side of the inclined plate 5 through the filtering membrane 44, the inclined plate 5 is used for inclined fixation, so that the cells of the Wharton's jelly flow to the butt joint groove 6 in a concentrated manner, the connecting pad 7 is made of rubber material, and the connecting pad 7 is extruded with the butt joint groove 6, so that the connecting pad 7 and the butt joint groove 6 form a sealing structure, the cells of the Wharton's jelly are not easy to leak through the butt joint groove 6, the fixing block 8 is rotated, the fixing block 8 and the material receiving box 42 are in threaded connection, the fixing block 8 drives the connecting pad 7 to separate from the material receiving box 42, and the cells of the Wharton's jelly can be discharged through the butt joint groove 6, so that the umbilical mesenchymal stem cell extraction separation device is convenient to take out the cells of the Wharton's jelly.
In summary, when the extraction and separation device is used, the first motor 21 and the second motor 22 are started, the output shaft of the first motor 21 and the output shaft of the second motor 22 respectively drive the cutting roller 3 and the connecting roller 31 to rotate, the hualong gum is placed on the upper side of the material receiving plate 13 through the feeding hole 11, the hualong gum moves towards the cutting roller 3 along the material receiving plate 13, the cutting roller 3 can uniformly cut up the hualong gum, the umbilical cord mesenchymal stem cell extraction and separation device is convenient for uniformly cutting up the hualong gum, the fixing block 8 is rotated, the fixing block 8 drives the connecting pad 7 to separate from the material receiving box 42, so that the hualong gum cells can be discharged through the abutting groove 6, and the umbilical cord mesenchymal stem cell extraction and separation device is convenient for taking out the hualong gum cells.
Although the present utility model has been described with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements and changes may be made without departing from the spirit and principles of the present utility model.
Claims (7)
1. Umbilical cord mesenchymal stem cells draws separator, including separation box body (1) and feed inlet (11), its characterized in that:
the upper side of separation box body (1) is fixed with feed inlet (11), and feed inlet (11) dock with apron (12), the inboard of separation box body (1) is fixed with and connects flitch (13), and the outside of separation box body (1) is provided with actuating mechanism (2), actuating mechanism (2) are including first motor (21) and second motor (22), first motor (21) and second motor (22) are installed in proper order in the outside of separation box body (1), the below that connects flitch (13) is passed through bearing and cutting roller (3) swing joint separation box body (1), the output shaft of first motor (21) is fixed with cutting roller (3), the output shaft of second motor (22) is fixed with connecting roller (31).
2. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 1, wherein: the lower side of separation box body (1) is provided with draws box body mechanism (4), and draws box body mechanism (4) including butt joint board (41), connect magazine (42), fixed plate (43) and filtration membrane (44), the downside of separation box body (1) is with butt joint board (41) butt joint.
3. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 2, wherein: the lower side of the butt plate (41) is fixed with a receiving box (42), and the inner side of the receiving box (42) is fixed with a fixing plate (43).
4. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 3, wherein: a filtering membrane (44) is arranged on the upper side of the fixing plate (43).
5. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 3, wherein: an inclined plate (5) is fixed on the inner side of the material receiving box (42), and a butt joint groove (6) is formed in one side of the inclined plate (5) of the material receiving box (42).
6. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 5, wherein: the butt joint groove (6) is in butt joint with the connecting pad (7), and one side of the connecting pad (7) is connected with the fixed block (8).
7. The umbilical cord mesenchymal stem cell extraction and separation device according to claim 6, wherein: the fixed block (8) is in butt joint with the receiving box (42).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321635452.8U CN220467967U (en) | 2023-06-26 | 2023-06-26 | Umbilical cord mesenchymal stem cell extraction and separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321635452.8U CN220467967U (en) | 2023-06-26 | 2023-06-26 | Umbilical cord mesenchymal stem cell extraction and separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220467967U true CN220467967U (en) | 2024-02-09 |
Family
ID=89803465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321635452.8U Active CN220467967U (en) | 2023-06-26 | 2023-06-26 | Umbilical cord mesenchymal stem cell extraction and separation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220467967U (en) |
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2023
- 2023-06-26 CN CN202321635452.8U patent/CN220467967U/en active Active
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