CN209790636U

CN209790636U - Tumor positioning and marking device

Info

Publication number: CN209790636U
Application number: CN201821467955.8U
Authority: CN
Inventors: 王巍炜; 王绍佳; 张勇; 巫正伟; 雷青; 毕书锋; 赵常坤; 缪祥帅; 李娜
Original assignee: Third Affiliated Hospital of Kunming Medical University
Current assignee: Third Affiliated Hospital of Kunming Medical University
Priority date: 2018-09-07
Filing date: 2018-09-07
Publication date: 2019-12-17
Anticipated expiration: 2028-09-07

Abstract

The utility model provides a tumour location mark device, its characterized in that, includes the location mark pipe, the location mark pipe is the closed netted pipe in both ends that body and pipe cap are constituteed, and the net of netted pipe is the hexagon structure, and the net surface coating that constitutes the location mark pipe has the fluorescence marker, the length L of location mark pipe be 20 ~ 40nm, the body diameter D of location mark pipe is 10 ~ 20nm, the location mark pipe chooses for use carbon nanometer-chitosan degradable material to make, the fluorescence marker chooses for use fluorescein isothiocyanate. The device has smaller volume, can be injected into tumor tissues along with injection through the injection device, and is convenient to operate; the device is degradable and does not need to be taken out by operation; the device can not only carry out positioning marking on the tumor tissue body, but also carry out positioning marking on the accessory tumor tissue formed by metastasis.

Description

tumor positioning and marking device

Technical Field

The utility model relates to a tumour location technical field, concretely relates to tumour location mark device.

Background

The tumor can be rapidly and instantly positioned, the marker is firmly attached in the tumor and does not shift, and the problem of tumor mobility (tumor can move) is always a technical problem in the medical field. The marker is dynamically tracked, and then the tumor is positioned in real time, so that the radiotherapy equipment can more accurately position the tumor, the damage to the healthy tissues of the human body is reduced, and the technical effect which needs to be achieved in clinic is needed. At present, a marking device helpful for tumor positioning is needed, which enables radiotherapy equipment to accurately and dynamically track the position of a tumor, improves the accuracy of tumor positioning, and reduces the harm to the health of a patient.

In order to solve the above problem, utility model No. 201720111363.1 discloses a tumour positioner, including marker body and fixing device, the marker body is the cylinder form, fixing device is fixed to be set up on the side of marker body, the material of marker body is pure gold, fixing device's shape is "people" font. However, this device has the following disadvantages: (1) the marker body has large volume and is difficult to degrade and exists in tumor tissues all the time, so that the tumor tissues are easy to distort and even break to cause cancer cell metastasis, and serious harm is caused to human bodies; (2) since tumor diagnosis requires a period of time for tumor resection, during which tumor cells lyse, metastasize, and generate collateral tumor tissue, the body of the marker is difficult to dynamically track and effectively locate and mark the generated collateral tumor tissue.

SUMMERY OF THE UTILITY MODEL

In order to solve the problems, the utility model designs a tumor positioning and marking device, which has smaller volume, can be injected into tumor tissues along with injection by an injection device and has convenient operation; the device is degradable and does not need to be taken out by operation; the device can not only carry out positioning marking on the tumor tissue body, but also carry out positioning marking on the accessory tumor tissue formed by metastasis.

in order to realize the technical purpose, reach above-mentioned technological effect, the utility model discloses a realize through following technical scheme:

The utility model provides a tumour location mark device, its characterized in that, includes the location mark pipe, the location mark pipe is the closed netted pipe in both ends that body and pipe cap are constituteed, and the net of netted pipe is the hexagon structure, and the net surface coating that constitutes the location mark pipe has the fluorescence marker, the length L of location mark pipe be 20 ~ 40nm, the body diameter D of location mark pipe is 10 ~ 20nm, the location mark pipe chooses for use carbon nanometer-chitosan degradable material to make, the fluorescence marker chooses for use fluorescein isothiocyanate.

Preferably, the length L of the positioning mark tube is 30nm, and the diameter D of the tube body is 10 nm.

The utility model has the advantages that: the device has smaller volume, can be injected into tumor tissues along with injection through the injection device, and is convenient to operate; the device is degradable and does not need to be taken out by operation; the device can not only carry out positioning marking on the tumor tissue body, but also carry out positioning marking on the accessory tumor tissue formed by metastasis.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a schematic structural diagram of a tumor location marker device;

Fig. 2 is a sectional view a-a of a tumor localization marker device.

In the drawings, the components represented by the respective reference numerals are listed below:

1-positioning a marker tube, 11-a tube cap and 2-a fluorescent marker.

Detailed Description

the technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

Referring to fig. 1-2, a tumor positioning and marking device is characterized by comprising a positioning and marking tube, wherein the positioning and marking tube 1 is a mesh tube with two closed ends and a tube cap 11, the mesh of the mesh tube is of a hexagonal structure, the surface of the mesh forming the positioning and marking tube 1 is coated with a fluorescent marker 2, the length L of the positioning and marking tube 1 is 20-40 nm, the diameter D of the tube body of the positioning and marking tube 1 is 10-20 nm, the positioning and marking tube 1 is made of carbon nano-chitosan degradable material, and the fluorescent marker 2 is fluorescein isothiocyanate.

Wherein, the length L of the positioning mark tube 1 is 30nm, and the diameter D of the tube body is 10 nm.

The positioning marking tube adopts a net-shaped nano structure made of carbon nano-chitosan degradable materials, has the advantages of small volume and easy injection, and the mixed solution of the positioning marking tube is directionally injected into tumor tissues by matching with a CT machine through an injection device (such as an injector and the like); the pathological section examination is needed for the definite diagnosis of the lung and chest tumor patients, as the pathological section examination and the related detection measures need a period of time, in the process of the definite diagnosis, the tumor tissues of the tumor patients are still in the infinite proliferation process, and the tumor cells of part of malignant tumor patients can have the condition of metastasis, while the tumor tissues injected with the positioning mark tube 1 absorb the fluorescent marker 2 coated on the surface of the positioning mark tube 1, namely fluorescein isothiocyanate, during the proliferation process, the tumor tissues are marked by using a fluorescent marking method and are positioned by matching with the fluorescent development generated during the radiation examination of a CT machine; when the malignant tumor cells marked by the fluorescent marker 2 and the accessory tumor tissue generated after the metastasis of the malignant tumor cells are diagnosed and are subjected to resection operation, the fluorescent marker 2 generates fluorescence under the excitation of X rays by matching with X ray examination of a CT machine, and the tumor tissue and the accessory tumor tissue can be positioned; the carrier of the fluorescent marker 2, namely the positioning marker tube 1 can be degraded and adsorbed by tumor cells, the volume of the carrier is gradually reduced along with the time, and the problem of tumor metastasis caused by the rupture of tumor tissues can be avoided; when the tumor tissue is benign tissue, the positioning mark tube 1 can be degraded, so that the positioning mark tube 1 is not required to be taken out in an operation, and the marking is safer.

In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. The utility model provides a tumour location mark device, its characterized in that, includes the location mark pipe, the location mark pipe is the closed netted pipe in both ends that body and pipe cap are constituteed, and the net of netted pipe is the hexagon structure, and the net surface coating that constitutes the location mark pipe has the fluorescence marker, the length L of location mark pipe be 20 ~ 40nm, the body diameter D of location mark pipe is 10 ~ 20nm, the location mark pipe chooses for use carbon nanometer-chitosan degradable material to make, the fluorescence marker chooses for use fluorescein isothiocyanate.

2. The tumor location and marking device according to claim 1, wherein the location and marking tube has a length L of 30nm and a tube diameter D of 10 nm.