CN209555197U - It is a kind of for biological cell feed back before liquid filling device - Google Patents
It is a kind of for biological cell feed back before liquid filling device Download PDFInfo
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- CN209555197U CN209555197U CN201822173070.3U CN201822173070U CN209555197U CN 209555197 U CN209555197 U CN 209555197U CN 201822173070 U CN201822173070 U CN 201822173070U CN 209555197 U CN209555197 U CN 209555197U
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- cell
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- filling device
- liquid filling
- device before
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Abstract
The utility model provides a kind of liquid filling device before feeding back for biological cell, it includes support frame, injector syringe, blood transfusion apparatus dropper, the first luer connector, flow control valve, the second luer connector, cell screen clothes and cell collection container, wherein, support frame includes rack, pedestal and support rod；Rack is provided with opening, injector syringe insertion opening, so that the piston end of injector syringe is connected in rack, the piston end of injector syringe is arranged in cell screen clothes；The needle end of injector syringe connects one end of blood transfusion apparatus dropper by the first luer connector, and the other end of blood transfusion apparatus dropper is connect by the second luer connector with cell collection container, and blood transfusion apparatus dropper is internally provided with filter screen.Liquid filling device before the feedback provided by the utility model for biological cell, cell pipeline closure is strong, by filtering twice, can substantially reduce the probability of cell contamination and operation infection to avoid the entrance of cell mass and impurity.
Description
Technical field
The utility model relates to biological therapy area of medical devices, and in particular to it is a kind of for biological cell feed back before filling
Liquid device.
Background technique
Biological therapy is all used widely in each field as a kind of new disease treatment means, belongs to personalization
Therapy system can not achieve batch production, and operation controllability is poor, guarantee that product quality is particularly important.
Routine Test Lab directly injects cell suspension in sky blood bag after mostly using syringe to aspirate when cell is filling,
This method can not only destroy cell, reduce activity, but also there is very big pollution risk.
Therefore, it needs to develop the biological cell feedback that a kind of pipeline closure is strong, reduce cell contamination, reduces cell cracks
Preceding liquid filling device.
The above-mentioned statement to background technique it is merely for convenience to technical solutions of the utility model (technological means that uses,
The technical issues of solution and the technical effect of generation etc.) deep understanding, and be not construed as recognizing or with any
Form implies that the information constitutes the prior art known to those skilled in the art.
Utility model content
In view of this, the present invention provides the liquid filling device before a kind of feedback for biological cell, cell pipelines
Closure is strong, and is mounted with cell screen clothes, by filtering twice, can substantially reduce to avoid the entrance of cell mass and impurity
Cell contamination and the probability of operation infection.
In an embodiment of the utility model, provide it is a kind of for biological cell feed back before liquid filling device,
It include support frame, injector syringe, blood transfusion apparatus dropper, the first luer connector, flow control valve, the second luer connector,
Cell screen clothes and cell collection container, wherein support frame as described above includes rack, pedestal and support rod, the both ends of the support rod
It is connect respectively with an edge at an edge of the rack and the pedestal, the rack and the pedestal are arranged in parallel；
The rack is provided with opening, and the injector syringe is inserted into the opening, so that the piston end of the injector syringe is clamped
In the rack, the piston end of the injector syringe is arranged in the cell screen clothes；The needle end of the injector syringe
One end of the blood transfusion apparatus dropper is connected by first luer connector, the other end of the blood transfusion apparatus dropper passes through described
The connection of the fluid flow tube of second luer connector and cell collection container, and then connect the cell collection container, the fluid flow tube
Upper setting flow control valve, the blood transfusion apparatus dropper are internally provided with filter screen.
In a specific embodiment, in side of the rack far from the pedestal, the edge of the opening is set
It is equipped with outer, the outer is that the edge of the opening is upwardly extended from the rack and formed.
In an optional embodiment, the height of the outer is 0.3-0.8cm.
In an optional embodiment, the opening is circle, a diameter of 2.5-4cm.
In an optional embodiment, the rack is square, side length 5-8cm.
In an optional embodiment, the pedestal is square, side length 7-10cm.
In an optional embodiment, the length of the support rod is 20-40cm.
In an optional embodiment, the injector syringe comes from 50ml disposable syringe.
In an optional embodiment, the cell collection container is disposable empty blood bag.
As it can be seen that the advantages of being used for the liquid filling device before biological cell is fed back provided by the utility model, is in avoiding routine
Syringe perfusion reduces pollution risk to cell damage；Outer is used to support injector syringe tail end, avoids
Cartridge inlet is directly contacted with rack plane, and when reducing liquid spillage, liquid, which backflows, to be polluted.Use provided by the utility model
In liquid filling device before biological cell feedback, cell sufficiently removes cell mass and granule foreign etc. after filtering twice.
Detailed description of the invention
Fig. 1: one of the embodiments of the present invention are for the liquid filling device structural schematic diagram before biological cell feedback.
Specific embodiment
The purpose of this utility model and advantage for ease of understanding will now combine the attached drawing of the utility model, to technical solution
It is described in detail.Case study on implementation discussed below is only a part in the utility model, is not construed as practical to this
Novel concrete restriction.
It is to be appreciated that appended attached drawing is not proportionally drawn, and merely to illustrating the basic principle of the utility model
Various features the suitably simplified technique of painting.The specific design feature of the utility model disclosed herein includes for example specific ruler
Very little, direction, position and shape will be partly determined by the specific application and use environment.
In the present specification, the top for defining Fig. 1 is the upper end or upside of the liquid filling device before feeding back for biological cell；
The lower section of Fig. 1 is the liquid filling device lower end or downside before feeding back for biological cell.In the present specification, the head of injector syringe
End or needle end refer to one end of injection syringe connecting needle, and the tail end or piston end of injector syringe refer to injector syringe
It is inserted into one end of piston.
Fig. 1 is the liquid filling device structural representation before one of the embodiments of the present invention are fed back for biological cell
Figure.As shown in Figure 1, provide in the present embodiment it is a kind of for biological cell feed back before liquid filling device comprising support frame
1, injector syringe 2, blood transfusion apparatus dropper 3, the first luer connector 4, flow control valve 5, the second luer connector 6, cell sieve
Net 7 and cell collection container 8.
In the present embodiment, support frame 1 includes rack 101, pedestal 102 and support rod 103, the both ends point of support rod 103
It is not connect with an edge at an edge of rack 101 and pedestal 102, rack 101 and pedestal 102 are arranged in parallel.
In the present embodiment, rack 101 is provided with opening, and injector syringe 2 is inserted into the opening, so that injector syringe 2
Piston end be connected in rack 101, the piston end of injector syringe 2 is arranged in cell screen clothes 7.Cell suspension first passes through when filling
It crosses the cell screen clothes 7 to be filtered, enters injector syringe 2 later.Cell screen clothes 7 are for filling preceding filtration cell group and particle
Commercially available any cell screen clothes, such as disposable cell screen clothes (the BD FALCON of BD company can be used in impurity etc.
352340)。
In the present embodiment, the needle end of injector syringe 2 connects blood transfusion apparatus dropper 3 by the first luer connector 4
The other end of one end, blood transfusion apparatus dropper 3 is connect by the second luer connector 6 with the fluid flow tube of cell collection container 8, Jin Erlian
Connect cell collection container 8.
In the present embodiment, flow control valve 5 is set on fluid flow tube, is used to control perfusion flow velocity and perfusion volume.
Flow control valve 5 can be simple hose intermediate plate, be rest directly upon on the fluid flow tube of cell collection container 8.Specifically, may be used
To blind off a line in perfusion, pipeline is opened after quantitative, suspension can flow into cell collection container 8 naturally.
In the present embodiment, blood transfusion apparatus dropper 3 is internally provided with filter screen 301, is used for filtering biological cell suspension.
Therefore, cell suspension successively passes through the filter screen 301 built in cell screen clothes 7 and blood transfusion apparatus dropper 3 when filling, to carry out twice
Filtering.
In a specific embodiment, support frame 1 can be made of stainless steel material.The rack 101 of support frame 1 can be with
It is square, side length 5-8cm.Preferably, rack 101 is having a size of 6cm × 6cm.The pedestal 102 of support frame 1 can be pros
Shape, side length 7-10cm.Preferably, pedestal 102 is having a size of 8cm × 8cm.The length of support rod 103 is 20-40cm.Preferably,
The length of support rod 103 is 30cm.
In a specific embodiment, the opening being arranged in rack 101 is circle, a diameter of 2.5-4cm.It is preferred that
Ground, the diameter of opening are 3.2cm.Specifically, opening is located at the center of rack 101.
In a specific embodiment, in the side of the separate pedestal 102 of rack 101, the edge of opening is provided with outer
Along 104, the edge for opening is upwardly extended from rack 101 and is formed.Specifically, the height of outer 104 is 0.3-0.8cm.
Preferably, the height of outer 104 is 0.5cm.
In a specific embodiment, injector syringe 2 is 50ml disposable syringe.Injector syringe 2, which comes from, appoints
What commercially available 50ml disposable syringe, the 50ml of such as, but not limited to Changchun Kingcon source medical appliance Co., Ltd are disposably infused
Emitter.Injector syringe, is only placed in rack by the piston core pin and syringe needle for giving up syringe when use.
In a specific embodiment, blood transfusion apparatus dropper 3 is commercially available any blood transfusion apparatus dropper, is such as, but not limited to come
Self-cleaning auspicious disposable transfusion set.
In a specific embodiment, the first luer connector 4 and the second luer connector 6 are commercially available any Rule
Connector, the plastics male and female Rule connecting interface for plastic cement of such as, but not limited to speeding in.
In a specific embodiment, flow control valve 5 be commercially available any flow control valve, such as, but not limited in
It speeds the hose intermediate plate of plastic cement.
In a specific embodiment, cell collection container 8 is any commercially available disposable empty blood bag.Such as it is but unlimited
In the 100ml empty bag high from Shandong prestige.
In a specific embodiment, above-mentioned blood transfusion apparatus dropper, luer connector are medical grade polypropylene (pp) new
Material is made, the transparent acid and alkali-resistance of color itself, resistant to dissolution, heatproof, meets American-European hygienic grade standard, and gas-liquid media general connects before use
It is stand-by to connect high pressure sterilization.
When carrying out filling cell suspension using the liquid filling device before the feedback provided by the utility model for biological cell,
After need to integrally being wiped with alcohol swab to support frame move into Biohazard Safety Equipment table top (or directly in safety cabinet ultraviolet lamp shine
Penetrate), disposable syringe packaging is torn first, is taken out injector syringe, is given up syringe piston core bar and syringe needle, be placed in support
In the rack of frame, then blood transfusion apparatus dropper is connected with injector syringe and cell collection container respectively by luer connector,
Flow control valve is closed, the disposable cell screen clothes of BD are placed in the piston end of injector syringe, finally slowly pours into and prepares
Cell suspension, open flow control valve after quantitative, cell suspension slowly flows into cell collection container, finally exhaust, heat seal
Nozzle.
The advantages of being used for the liquid filling device before biological cell is fed back provided by the utility model, is in avoiding regular injection
Device perfusion reduces cell activity to cell damage, while reducing pollution risk；The rack hollow rim of support frame is set
There is outer, be used to support injector syringe tail end, cartridge inlet is avoided directly to contact with rack plane, when reducing liquid spillage,
Liquid, which backflows, to be polluted.In the liquid filling device before the feedback provided by the utility model for biological cell, cell passes through two
After secondary filtering, sufficiently remove cell mass and granule foreign etc., make to feed back it is safer, avoid fever, shiver etc. it is bad instead
The generation answered.Present apparatus flow liquid system is that Dispoable medical grade polypropylene (pp) virgin material is made, the transparent acid and alkali-resistance of color itself, resistance to
Dissolution, heatproof meet American-European hygienic grade standard, and gas-liquid media general is more in line with the preparation requirement of personalized biological treatment, can
To be used widely.
The description that foregoing exemplary embodiment is presented is only to illustrate the technical solution of the utility model, is not intended to
As without missing, also it is not intended to the utility model to be limited to described precise forms.Obviously, the common skill of this field
Art personnel make many changes according to the above instruction and variation is all possible.Selection illustrative embodiments are simultaneously described and are
In order to explain the certain principles and practical application of the utility model, so that others skilled in the art are convenient for reason
Solve, realize and utilize the various illustrative embodiments and its various selection forms and modification of the utility model.This is practical
Novel protection scope is intended to be limited by the appended claims and its equivalents.
Claims (9)
1. the liquid filling device before a kind of feedback for biological cell, which is characterized in that it includes support frame (1), injector syringe
(2), blood transfusion apparatus dropper (3), the first luer connector (4), flow control valve (5), the second luer connector (6), cell screen clothes
(7) and cell collection container (8), wherein
Support frame as described above (1) includes rack (101), pedestal (102) and support rod (103), the both ends point of the support rod (103)
It is not connect with an edge at an edge of the rack (101) and the pedestal (102), the rack (101) and the pedestal
(102) arranged in parallel；
The rack (101) is provided with opening, and the injector syringe (2) is inserted into the opening, so that the injector syringe
(2) piston end is connected on the rack (101), piston of cell screen clothes (7) setting in the injector syringe (2)
End；
The needle end of the injector syringe (2) connects the blood transfusion apparatus dropper (3) by first luer connector (4)
One end, the other end of the blood transfusion apparatus dropper (3) pass through the liquid of second luer connector (6) and cell collection container (8)
Flow tube connection, and then the cell collection container (8) is connected, flow control valve (5) are set on the fluid flow tube, the blood transfusion apparatus
Dropper (3) is internally provided with filter screen (301).
2. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that in the rack
(101) far from the side of the pedestal (102), the edge of the opening is provided with outer (104), and the outer (104) is institute
The edge for stating opening is upwardly extended from the rack (101) and is formed.
3. the liquid filling device before the feedback according to claim 2 for biological cell, which is characterized in that the outer
(104) height is 0.3-0.8cm.
4. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the opening is circle
Shape, a diameter of 2.5-4cm.
5. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the rack
(101) it is square, side length 5-8cm.
6. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the pedestal
(102) it is square, side length 7-10cm.
7. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the support rod
(103) length is 20-40cm.
8. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the syringe needle
Cylinder (2) comes from 50ml disposable syringe.
9. the liquid filling device before the feedback according to claim 1 for biological cell, which is characterized in that the cell is collected
Container (8) is disposable empty blood bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822173070.3U CN209555197U (en) | 2018-12-24 | 2018-12-24 | It is a kind of for biological cell feed back before liquid filling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822173070.3U CN209555197U (en) | 2018-12-24 | 2018-12-24 | It is a kind of for biological cell feed back before liquid filling device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209555197U true CN209555197U (en) | 2019-10-29 |
Family
ID=68303345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201822173070.3U Active CN209555197U (en) | 2018-12-24 | 2018-12-24 | It is a kind of for biological cell feed back before liquid filling device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209555197U (en) |
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2018
- 2018-12-24 CN CN201822173070.3U patent/CN209555197U/en active Active
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