CN209387380U - A kind of magnetic separating device and device for analyzing samples - Google Patents
A kind of magnetic separating device and device for analyzing samples Download PDFInfo
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- CN209387380U CN209387380U CN201821439572.XU CN201821439572U CN209387380U CN 209387380 U CN209387380 U CN 209387380U CN 201821439572 U CN201821439572 U CN 201821439572U CN 209387380 U CN209387380 U CN 209387380U
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Abstract
The utility model discloses a kind of magnetic separating device and device for analyzing samples, which includes: Magneto separate unit comprising: Magneto separate disk, it is provided at least one and puts cup position, to accommodate placing response container, wherein be equipped with the magnetic bead and solution for carrying out immunoassay test in reaction vessel；An at least magnet, it respectively corresponds and is placed on described at least one and puts in cup position, wherein, each described put places corresponding annular magnet in cup position, with the reaction vessel be placed on it is described put cup position when, the magnetic bead is adsorbed on to the inner wall of the reaction vessel using the magneticaction for putting the annular magnet in cup position, avoids that the magnetic bead is discharged in the waste liquid being discharged in the reaction vessel.By the above-mentioned means, the utility model can be avoided waste caused by the magnetic bead is discharged, while pipeline being avoided to be blocked by the magnetic bead.
Description
Technical field
The utility model relates to the field of medical instrument technology, fill more particularly to a kind of magnetic separating device and sample analysis
It sets.
Background technique
Immuno magnetic cell separation technology is combine immunologic high degree of specificity with the distinctive magnetic responsiveness of magnetic bead one
Kind new isolation technics is the immunological detection method and antigen purification means of a kind of high specificity, high sensitivity, this technology
Cell separation, Protein Detection, immunology detection and in terms of be used widely.
To separate object of the non-targeted object of free state in conjunction with magnetic bead, need to carry out reactant in magnetic field
Magneto separate and cleaning, cleaning process are then to refill cleaning solution, such as by supernatant waste liquid in abstraction reaction cup in magnetic field
This iterative cycles is completed, and the loss late of target magnetic bead and the effect of Magneto separate are closely related in cleaning process.And relative to suction
The pressure for taking supernatant liquid pump, in the case where specified magnetic field strength, Aspirate supernatant pump negative pressure is excessive, will lead to and is attached to reaction
Magnetic bead on cup inner wall is sucked away, this allows for not only causing in the liquid of drain needle discharge there are a large amount of immunomagnetic beads
The waste of immunomagnetic beads, can also block respective line leads to equipment fault.
Present inventor has found in existing magnetic separating device in long-term R&D process, the loss late of magnetic bead
Greatly, and it is easy to appear the failure of pipeline blockage.
Utility model content
The utility model is mainly solving the technical problems that provide a kind of secondary separator and device for analyzing samples, Neng Gou
Waste caused by avoiding the magnetic bead from being discharged during Magneto separate, while pipeline being avoided to be blocked by the magnetic bead.
In order to solve the above technical problems, the technical solution that the utility model uses is: providing a kind of magnetic separating device.
Wherein, described device includes:
Magneto separate unit comprising:
Magneto separate disk is provided at least one and puts cup position, to accommodate placing response container, wherein hold in reaction vessel
It is equipped with the magnetic bead and solution for carrying out immunoassay test；
An at least annular magnet respectively corresponds and is placed on described at least one and puts in cup position, wherein each described to put in cup position
Place corresponding annular magnet, with the reaction vessel be placed on it is described put cup position when, using described in described put in cup position
The magnetic bead is adsorbed on the inner wall of the reaction vessel by the magneticaction of annular magnet, is avoided in the reaction vessel is discharged
Waste liquid when the magnetic bead is discharged.
In order to solve the above technical problems, another technical solution that the utility model uses is: providing a kind of sample analysis
Device.
Wherein, the device for analyzing samples includes any magnetic separating device and sample testing apparatus.
The beneficial effects of the utility model are: be in contrast to the prior art, the utility model is by setting putting cup position
Set annular magnet so that the reaction vessel be placed on it is described when putting cup position, by institute under the magneticaction of the annular magnet
The inner wall that magnetic bead is adsorbed on the reaction vessel is stated, realizes the Magneto separate of the magnetic bead.And the annular magnet can be to described
Reaction vessel applies more stable and bigger magnetic field strength magnetic field, more magnetic beads can be adsorbed on the reaction vessel
Inner wall, improves the separative efficiency of the magnetic bead, and then waste caused by avoiding the magnetic bead from being discharged, and also avoids pipeline described
Magnetic bead blocking.
Detailed description of the invention
It, below will be to required in embodiment description in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
Attached drawing to be used is briefly described, it should be apparent that, the accompanying drawings in the following description is only some realities of the utility model
Example is applied, it for those of ordinary skill in the art, without creative efforts, can also be according to these attached drawings
Obtain other attached drawings.Wherein:
Fig. 1 is a kind of structural schematic diagram of one embodiment of magnetic separating device of the utility model；
Fig. 2 is the sectional view of magnetic separating device described in Fig. 1；
Fig. 3 is the structural schematic diagram of one embodiment of the utility model drain unit；
Fig. 4 is the structural schematic diagram of one embodiment of the utility model cleaning unit；
Fig. 5 is a kind of flow diagram of one embodiment of magnetism separate method of the utility model；
Fig. 6 is a kind of flow diagram of one embodiment of magnetism separate method of the utility model；
Fig. 7 is a kind of structural schematic diagram of one embodiment of device for analyzing samples of the utility model.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
It clearly and completely describes, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than all real
Apply example.Based on the embodiments of the present invention, those of ordinary skill in the art are not under the premise of making creative labor
Every other embodiment obtained, fall within the protection scope of the utility model.
Refering to fig. 1 and Fig. 2, Fig. 1 are a kind of structural schematic diagram of one embodiment of magnetic separating device of the utility model, Fig. 2
It is the sectional view of magnetic separating device in Fig. 1, which includes:
Magneto separate unit comprising: Magneto separate disk 10 is provided at least one and puts cup position 20, to accommodate placing response
Container 30, wherein the magnetic bead and solution for carrying out immunoassay test are equipped in the reaction vessel；An at least annular magnet
40, it respectively corresponds and is placed on described at least one and puts in cup position 20, wherein each described put places corresponding annular magnetic in cup position 20
Iron 40, with the reaction vessel 30 be placed on it is described put cup position 20 when, utilize the annular magnet put in cup position 20
The magnetic bead is adsorbed on the inner wall of the reaction vessel 30 by 40 magneticaction, is avoided in the reaction vessel 30 is discharged
The magnetic bead is discharged when waste liquid.
In the present embodiment, by the way that annular magnet is arranged putting cup position so that the reaction vessel 30 be placed on it is described
When putting cup position 20, the magnetic bead is adsorbed on to the inner wall of the reaction vessel 30 under the magneticaction of the annular magnet 40,
Realize the Magneto separate of the magnetic bead.And the annular magnet 40 can be strong to the more stable and magnetic field of the reaction vessel 30 application
Bigger magnetic field is spent, more magnetic beads can be adsorbed on to the inner wall of the reaction vessel 30, improves the separation effect of the magnetic bead
Rate, and then waste caused by avoiding the magnetic bead from being discharged, also avoid pipeline from being blocked by the magnetic bead.
In the present embodiment, the annular magnet 40 surround it is described put around cup position 20, the annular magnet 40 can
To be permanent magnet, it is also possible to electromagnet.In one embodiment, to further reduce the cost, the annular magnet 40 is
When permanent magnet, the annular magnet 40 has different thickness along the extending direction for putting cup position, to cooperate the reaction to hold
The distributed number gradient of magnetic bead in 30 different zones of device.Further, in order to be accurately controlled to magnetic field strength, the ring
Shape magnet 40 is electromagnet, and the electromagnet connects to the control circuit.Further, the electromagnet is put to be multiple along described
The annular magnet unit of the extending direction distribution of cup position, and each annular magnet unit is connect with individual control circuit,
So that the quantity of different zones magnetic bead is divided in the field strength distribution in the magnetic field that the annular magnet generates and the reaction vessel 30
Cloth gradient is corresponding, and realization efficiently separates the magnetic bead, while avoiding pump negative pressure is excessive to cause to be attached on reaction cup inner wall
Magnetic bead be sucked away cause waste and also avoid magnetic bead from entering pipeline for pipeline blockage.
In another embodiment, referring to FIG. 3, Fig. 3 is the structure of one embodiment of the utility model drain unit
Schematic diagram, pumping equipment 100 are used for the waste liquid being discharged in reaction vessel 30, for example, for anti-in immuno magnetic cell separation technology
Object is answered to carry out the supernatant in reaction cup used in Magneto separate and cleaning process.Pumping equipment 100 include drain needle 110,
Draw-off pump 120 and isolation ward 130, wherein the drain needle 110 is used to extract the waste liquid in the reaction vessel；The extraction
Pump 120, is connected by drain line with the drain needle 110, to provide extraction power for the drain needle 110；It is described
Isolation ward 130 is arranged in the drain line between the drain needle 110 and the draw-off pump 120, with the draw-off pump 120
Cooperate and buffers the extraction power for adjusting and being supplied to the drain needle.
In the present embodiment, the institute being arranged in the drain line between the drain needle 110 and the draw-off pump 120
Stating isolation ward 130 can cooperate with the draw-off pump 120 and adjust the extraction power for being supplied to the drain needle 110, the buffering
The method for adjusting extraction power is simple, can further decrease magnetic bead loss late, and fluid path device convenient for safeguarding.Namely it uses and sets
There is the Magneto separate unit of annular magnet to cooperate with the drain unit for being equipped with isolation ward, is retained in the reaction vessel in reduction
Waste liquid in magnetic bead number while, rationally adjust extract power, lower magnetic bead loss late can be obtained, pipeline is blocked up
The risk of plug further decreases, and convenient for the maintenance of related device, obtains better usage experience.
In the present embodiment, pumping equipment 100 can be an independent fluid path device, be also possible to some equipment
In fluid path unit, such as can be a fluid path unit of the cleaning device in immunity analysis instrument, can and cleaning device
In other fluid path units, such as cleaning unit for injecting cleaning solution is used cooperatively, to complete entire cleaning process.
Specifically, the drain needle 110 in pumping equipment 100 is for being inserted into reaction vessel in abstraction reaction container
Waste liquid, such as the supernatant in reaction cup.Draw-off pump 120 is connected by drain line 140 with drain needle 110, to be
Drain needle 110, which provides, extracts power, such as the extraction power of negative pressure.And isolation ward 130 is arranged in drain needle 110 and draw-off pump
In drain line 140 between 120, moved with cooperating with draw-off pump 120 to buffer and adjust the extraction for being supplied to drain needle 110
Power.
In the present embodiment, draw-off pump 120 can not need to be replaced as frequently as using diaphragm pump relative to peristaltic pump
Relevant pipeline, longer life expectancy help more preferably to go to safeguard simultaneously.The concrete structure design of drain line 140 can be according to reality
Using and determine, it is not limited here.Isolation ward 130 and diaphragm pump 120 are arranged in drain line 140, and isolation ward 130
It is connected with diaphragm pump 120, in this way when diaphragm pump 120 adjusts the extraction power of negative pressure, isolation ward 130 can play buffering negative pressure
Extract the effect of power.Diaphragm pump 120 can claim control to pump again, can receive the control of adjuster or computer in control process
Signal processed changes the flow of fluid, maintains adjusting parameter (for example, duty cycle parameters) in required range, to reach
To the automation of production process.
In addition, pumping equipment 100 may further include the first solenoid valve 150, such as two-bit triplet solenoid valve, inside set
It is equipped with closed chamber, is provided with through-hole in different location, it is piston among chamber that each hole, which connects different accesses, and two sides is two pieces
Which side the magnet coil energization valve body of electromagnet, which face will be attracted to, therefore, can by the movement of application valve body come
Open or close different through-holes.That is, two-bit triplet solenoid valve is twin coil control, closed after a coil moment energization
Power supply is closed, valve is opened, and corresponding access communicates with each other；Another coil moment closes power supply after being powered, and valve is closed, corresponding logical
Road communicates with each other.Two-bit triplet solenoid valve can remain turned-off for a long time or opening state, coil life can be made longer, in high temperature
Using best in pipeline.
In the present embodiment, as shown in figure 3, isolation ward 130 is provided with the first opening 131, second opening 132 and third is opened
Mouth 133, wherein the sidewall upper of isolation ward 130 is arranged in the first opening 131, and isolation ward 130 is arranged in the second opening 132
Side wall lower ends, and the top of isolation ward 130 is arranged in third opening 133.The normally open end 150A of first solenoid valve 150 passes through drain
Pipeline 140 and be connected to isolation ward 130 first opening 131, the normal-closed end 150B of the first solenoid valve 150 passes through drain line
140 and be connected to isolation ward 130 second opening 132, the working end 150C of the first solenoid valve 150 passes through drain line 140
It is connected to draw-off pump 120；And the third opening 133 of isolation ward 130 is connected to drain needle 110 by drain line 140.
In the present embodiment, diaphragm pump 120 can cooperate with the first solenoid valve 150, be input to pumping equipment to adjust
Negative pressure draft in 100, when the first solenoid valve 150 switches in normally open end 150A and opens, diaphragm pump 120 and isolation ward 130
First opening 131 be connected to be supplied to drain needle 110 normal work extraction forces, with the supernatant in abstraction reaction cup；
And when the first solenoid valve 150 switches in normal-closed end 150B and opens, the second 132 phases of opening of diaphragm pump 120 and isolation ward 130
Even, then the waste liquid accumulated in isolation ward 130 can be extracted.In entire discharge opeing process, isolation ward 130 can be to being input to drain
Negative pressure extracting power in device 100 plays the role of buffering and adjusts, so that the extraction force in drain needle 110 be made to be unlikely to too
By force, while avoiding supernatant of the drain needle 110 in abstraction reaction cup, the target magnetic bead in reaction cup has been extracted together.
In addition, waste liquid barrel 160 is arranged in drain pipe as shown in figure 3, pumping equipment 100 still further comprises waste liquid barrel 160
The end on road 140 is connect by drain line 140 with diaphragm pump 120.Therefore, pumping equipment 100 extracts the waste liquid of discharge
It can be injected into waste liquid barrel 160 by relevant access.
In another embodiment, the magnetic separating device further includes for be placed on the institute put on cup position 20
The cleaning unit 200 that reaction vessel 40 injects cleaning solution is stated, referring to FIG. 4, Fig. 4 is one embodiment party of the utility model cleaning unit
The structural schematic diagram of formula, the cleaning unit 200 are used to provide new cleaning solution for the reaction vessel 30.That is, working as
After the waste liquid (supernatant) that drain unit 100 has been discharged in reaction vessel 30 described in above-mentioned Fig. 3, can further it utilize
Cleaning unit 200 is to inject new cleaning solution in reaction vessel 30, again to object (e.g., the target in reaction vessel
Magnetic bead) it is cleaned, relevant waste liquid is discharged using drain unit 210 again after cleaning, to reach more to object progress
The purpose of secondary cleaning.
Specifically, cleaning unit 200 includes cleaning solution power supply unit 221, injection needle 222, plunger pump 223.Wherein, cleaning solution
Power supply unit 221 is for accommodating and supplying cleaning solution；Injection needle 222 is connected by fluid injection pipeline 225 and cleaning solution power supply unit 221
It connects, to obtain cleaning solution from cleaning solution power supply unit 221, and provides cleaning solution into reaction vessel；The setting of plunger pump 223 is being infused
It is connected on liquid pipeline 225 and with cleaning solution power supply unit 221 and injection needle 222, it will be in cleaning solution power supply unit 221 to provide power source
Cleaning solution be delivered in injection needle 222.
Further, the cleaning unit 220 can further comprise second solenoid valve 224, for example, two-position three-way electromagnetic
Valve.Wherein, the working end of second solenoid valve 224 is connected with plunger pump 223, the normally open end of second solenoid valve 224 and fluid injection pipeline
225 are connected, and the normal-closed end of second solenoid valve 224 is connected with cleaning solution power supply unit 221.Therefore, second solenoid valve 224 and plunger
223 cooperation of pump, the cleaning solution in cleaning solution power supply unit 221 is delivered to injection needle 222 using plunger pump 223 according to demand
In.
In addition, as shown in Figure 3 and Figure 4, in the present embodiment, the drain needle 110 in drain unit 100 may include simultaneously
Arrange the minute hand 1111 and hour hand 1112 of setting, wherein minute hand 1111 is connected to isolation ward 130 by drain line 216 and takes out
Pump 120 is taken to extract waste liquid, that is, realizes the function of drain.And hour hand 1112 close to minute hand 1111 be arranged, and with cleaning unit 200
Middle fluid injection pipeline 225 is connected, to obtain cleaning solution from cleaning unit 220 to carry out outer wall washing to minute hand 2111.
Specifically, in present embodiment, cleaning unit 200 can further comprise third solenoid valve 226, be arranged second
In fluid injection pipeline 225 between solenoid valve 224 and injection needle 222.Third solenoid valve 226 can use two-bit triplet solenoid valve,
The working end of third solenoid valve 226 is connected with fluid injection pipeline 225, and the normally open end of third solenoid valve 226 is connected with injection needle 222,
And the normal-closed end of third solenoid valve 226 is connected with hour hand 2112.That is, can be controlled by third solenoid valve 226 clear
Washing lotion is to be injected into injection needle 222, and to add cleaning solution to reaction cup, or control cleaning solution injects hour hand 1112, thus right
Minute hand 1111 carries out outer wall washing.
In another embodiment, please also refer to Fig. 1 and Fig. 3, the Magneto separate unit further comprises driving dress
50 are set, the driving mechanism 50 is connect to drive the rotation of Magneto separate disk 10 to make to be placed on institute with the Magneto separate disk 10
The reaction vessel 30 put on cup position 20 is stated to turn to 110 lower section of drain needle or turn under the injection needle 222
Side.In the present embodiment, the reaction vessel 30 put on cup position 20 to be made to turn to by driving mechanism 50 described
222 lower section of 110 lower section of drain needle or the injection needle, namely do not need repeatedly directly to move the reaction vessel 30
It can complete the process of drain and cleaning and wash away the impurity of magnetic bead surfaces, the magnetic separating device is compact-sized, corresponding to act
It is coherent, be conducive to improve operating efficiency.
Will be further, the Magneto separate unit further comprises manipulator (not shown), and the manipulator is used for will be complete
The reaction vessel 30 for cleaning and separating at magnetic bead is clamped from the Magneto separate disk 10 to area to be tested, subsequent to carry out
Detection.In the present embodiment, the subsequent detection can be immunoassay detection.It will be completed by the manipulator
The reaction vessel 30 of magnetic bead cleaning and separation is transferred to below specimen needle, and then is carried out compressing and mixed operation and be immunized
Detection operation.
In order to solve the above technical problems, another technical solution that the utility model uses is: providing a kind of Magneto separate side
Method.
Referring to FIG. 5, Fig. 5 is a kind of flow diagram of one embodiment of magnetism separate method of the utility model, wherein institute
State method comprising steps of
S100, the reaction vessel containing the magnetic bead and solution that carry out immunoassay test is placed in Magneto separate disk
It puts in cup position, and rotates the Magneto separate disk so that the reaction accommodating to be gone to the lower section of drain needle.
In the step S100, described put in the Magneto separate disk is provided with corresponding annular magnet in cup position, with
The magnetic bead of free state in the reaction vessel is set to be adsorbed to the inner wall of the reaction vessel under the action of annular magnet.
Specifically, the reaction vessel to Magneto separate is grabbed by the manipulator put cup position to the Magneto separate disk,
The lower part (that is, turning to crosspointer position) of the reaction vessel transposition drain needle put on cup position, and reaction unit rests on magnetic field
In.
S200, drain needle suitable position into the reaction vessel is moved down, and using described in drain needle discharge
Solution in reaction vessel.
In the step S200, the drain needle is under the driving of linear motor to the direction close to the reaction vessel
It is mobile, into the reaction vessel and it is moved to suitable position.Later, diaphragm pump is opened, while adjusting suitable diaphragm pump
Duty cycle parameters, supernatant waste liquid is expelled to waste liquid barrel under the action of the extraction power of negative pressure, through the minute hand of drain needle, with
The solution in the reaction vessel is discharged.Further, the first solenoid valve of switching is to normal-closed end, and full-load run separate pump is with will be every
It is evacuated from the residual liquid in room.
Further, referring to FIG. 6, the process that Fig. 6 is a kind of another embodiment of magnetism separate method of the utility model is shown
It is intended to, wherein the method also includes steps:
S300, the drain needle is removed, and rotates the Magneto separate disk so that the reaction vessel turns to the fluid injection
Below needle, to inject cleaning solution into the reaction vessel by the injection needle.
In the step S300, drain needle, the rotation of Magneto separate disk are removed, reaction unit turns to below injection needle (i.e.
Turn to single needle position), plunger pump is opened, and cleaning solution is injected into reaction cup by injection needle.Further, rabbling mechanism is inserted into
The appropriate location of the reaction unit is stirred, and is conducive to the impurity Rapid Cleaning of magnetic bead surfaces is clean, reduction cleaning time
Number.
S400, the Magneto separate disk is rotated again so that the reaction vessel turns to below the drain needle, in repetition
Step is stated to complete the Magneto separate cleaning operation of pre-determined number.
In the step S400, the Magneto separate disk is rotated again so that the reaction vessel turns to the drain needle
Lower section repeats the above steps to complete the Magneto separate cleaning operation of pre-determined number.The number of the Magneto separate cleaning operation can be with
The amount of the cleaning solution injected according to the quantity of the magnetic bead in reaction unit and every time is determined, and is not specifically limited herein.
In order to solve the above technical problems, another technical solution that the utility model uses is: providing a kind of sample analysis
Device.Referring to FIG. 7, Fig. 7 is a kind of structural schematic diagram of one embodiment of device for analyzing samples of the utility model, wherein institute
Stating device for analyzing samples 1 includes any magnetic separating device 10 and sample testing apparatus 20.The detection device 20 can be with
It is Immunofluorescence test device.
In conclusion the device includes: Magneto separate unit the utility model discloses a kind of magnetic separating device and method,
Comprising: which Magneto separate disk, is provided at least one and puts cup position, to accommodate placing response container, wherein accommodate in reaction vessel
There are the magnetic bead and solution for carrying out immunoassay test；An at least magnet respectively corresponds and is placed on described at least one and puts in cup position,
Wherein, each described put places corresponding annular magnet in cup position, with the reaction vessel be placed on it is described put cup position when, benefit
The magnetic bead is adsorbed on to the inner wall of the reaction vessel with the magneticaction for putting the annular magnet in cup position, is avoided
The magnetic bead is discharged in the waste liquid being discharged in the reaction vessel.By the above-mentioned means, the utility model can be avoided it is described
Waste caused by magnetic bead is discharged, while pipeline being avoided to be blocked by the magnetic bead.
The foregoing is merely the embodiments of the present invention, and therefore it does not limit the scope of the patent of the utility model, all
It is equivalent structure or equivalent flow shift made based on the specification and figures of the utility model, directly or indirectly uses
In other related technical areas, it is also included in the patent protection scope of the utility model.
Claims (12)
1. a kind of magnetic separating device characterized by comprising Magneto separate unit comprising:
Magneto separate disk is provided at least one and puts cup position, to accommodate placing response container, wherein be equipped in reaction vessel
Carry out the magnetic bead and solution of immunoassay test；
An at least annular magnet respectively corresponds and is placed on described at least one and puts in cup position, wherein each described put in cup position is placed
Corresponding annular magnet, with the reaction vessel be placed on it is described put cup position when, utilize the annular put in cup position
The magnetic bead is adsorbed on the inner wall of the reaction vessel by the magneticaction of magnet, avoids that giving up in the reaction vessel is being discharged
The magnetic bead is discharged when liquid.
2. magnetic separating device according to claim 1, which is characterized in that the annular magnet is permanent magnet, the permanent magnetism
Body has thickness gradient in the extending direction for putting cup position.
3. magnetic separating device according to claim 1, which is characterized in that the annular magnet is electromagnet, the magnetic point
It further include the control circuit being electrically connected with the electromagnet from device, the electromagnet includes multiple along the extension for putting cup position
The annular magnet unit of directional spreding, and each annular magnet unit is connect with individual control circuit unit.
4. magnetic separating device according to claim 1, which is characterized in that further comprise: drain unit comprising:
Drain needle, for extracting the waste liquid in the reaction vessel；
Draw-off pump is connected, to provide extraction power for the drain needle with the drain needle by drain line；
Isolation ward is arranged in the drain line between the drain needle and the draw-off pump, to cooperate with the draw-off pump
Buffering adjusts the extraction power for being supplied to the drain needle.
5. magnetic separating device according to claim 4, which is characterized in that further comprise:
Cleaning unit, for injecting cleaning solution to be placed on the reaction vessel put on cup position comprising:
Cleaning solution power supply unit, for accommodating and supplying cleaning solution；
Injection needle is connect, to be cleaned from the cleaning solution power supply unit with the cleaning solution power supply unit by fluid injection pipeline
Liquid, and cleaning solution is provided into the reaction vessel；
Plunger pump is arranged on the liquid injection pipe road and is connected with the cleaning solution power supply unit and the injection needle, dynamic to provide
Cleaning solution in the cleaning solution power supply unit is delivered in the injection needle by power source.
6. magnetic separating device according to claim 5, which is characterized in that the Magneto separate unit further comprises:
Driving device is connect to drive the Magneto separate disk rotation to make to be placed on described put on cup position with the Magneto separate disk
The reaction vessel turn to below the drain needle or turn to below the injection needle.
7. magnetic separating device according to claim 1, which is characterized in that the Magneto separate unit further comprises:
Manipulator, the reaction vessel for that will complete magnetic bead cleaning and separation are clamped from the Magneto separate disk to be detected
Region, to carry out subsequent detection.
8. magnetic separating device according to claim 5, which is characterized in that the drain needle include minute hand arranged side by side and
Hour hand, wherein the minute hand is connected to the isolation ward and the draw-off pump by drain line to extract waste liquid；And it is described
Hour hand is connected to obtain cleaning solution to the minute hand and clean with the fluid injection pipeline.
9. magnetic separating device according to claim 4, which is characterized in that the drain unit further comprises:
First solenoid valve is arranged in the drain line between the isolation ward and the draw-off pump, wherein first electromagnetism
Valve is two-position three way magnetic valve, and the isolation ward is provided with the first opening, the second opening and third opening, wherein described the
One opening is arranged in the sidewall upper of the isolation ward, and second opening is arranged in the side wall lower ends of the isolation ward, and institute
The top that the isolation ward is arranged in third opening is stated, the normally open end of first solenoid valve is connected to institute by drain line
The first opening of isolation ward is stated, the normal-closed end of first solenoid valve is connected to the second of the isolation ward by drain line
Opening, the working end of first solenoid valve is connected to the draw-off pump by drain line；And the third of the isolation ward
Opening is connected to the drain needle by drain line.
10. magnetic separating device according to claim 5, which is characterized in that the cleaning unit further comprises:
Second solenoid valve, wherein the working end of the second solenoid valve is connected with the plunger pump, the second solenoid valve it is normal
Beginning is connected with the fluid injection pipeline, and the normal-closed end of the second solenoid valve is connected with the cleaning solution power supply unit.
11. magnetic separating device according to claim 8, which is characterized in that the cleaning unit further comprises:
Third solenoid valve, wherein the working end of the third solenoid valve is connected with the fluid injection pipeline, the third solenoid valve
Normally open end is connected with the injection needle, and the normal-closed end of the third solenoid valve is connected with the hour hand.
12. a kind of device for analyzing samples, which is characterized in that the device for analyzing samples includes described in claim any one of 1-11
Magnetic separating device and sample testing apparatus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821439572.XU CN209387380U (en) | 2018-08-31 | 2018-08-31 | A kind of magnetic separating device and device for analyzing samples |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821439572.XU CN209387380U (en) | 2018-08-31 | 2018-08-31 | A kind of magnetic separating device and device for analyzing samples |
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| Publication Number | Publication Date |
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| CN209387380U true CN209387380U (en) | 2019-09-13 |
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| CN201821439572.XU Active CN209387380U (en) | 2018-08-31 | 2018-08-31 | A kind of magnetic separating device and device for analyzing samples |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112881725A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Sample detection equipment and magnetic cleaning and separating device and control method thereof |
-
2018
- 2018-08-31 CN CN201821439572.XU patent/CN209387380U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112881725A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Sample detection equipment and magnetic cleaning and separating device and control method thereof |
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