CN209379002U - A kind of cooler pan of parallel reaction instrument - Google Patents
A kind of cooler pan of parallel reaction instrument Download PDFInfo
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- CN209379002U CN209379002U CN201822095594.5U CN201822095594U CN209379002U CN 209379002 U CN209379002 U CN 209379002U CN 201822095594 U CN201822095594 U CN 201822095594U CN 209379002 U CN209379002 U CN 209379002U
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- cooler pan
- reaction tube
- parallel
- mesoporous
- reaction
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Abstract
The utility model provides a kind of cooler pan of parallel reaction instrument, setting passes through the mesoporous of reaction tube and the chute for cooling down reaction tube in mesoporous thereon, the carrying groove for picking and placing cooler pan is arranged in one end of not set runner on cooler pan, and edge of the cooler pan far from the center of circle is arranged in carrying groove.Carrying groove is made of three or four finger shape slots disposed in parallel, forms the carrying groove of impression of the hand shape.Cooler pan circumference face corresponds to the slot of the position setting thumb shape of finger shape slot.The carrying groove for picking and placing cooler pan is arranged in the utility model, and cooler pan and upper disk is facilitated to install or dismantle.Also facilitate by after test cooler pan and upper disk and reaction tube be fetched into together suitable position observation structure or carry out next step experiment.
Description
Technical field
The utility model belongs to chemistry and the reaction kits field such as bio-pharmaceuticals, and in particular to a kind of parallel reaction instrument it is cold
But disk.
Background technique
Parallel reaction instrument be it is a kind of research and development, test, exploitation used in instrument, can be realized parallel projects reaction, thus
Realize short form test, efficiently, the function accurately reacted.The equally distributed mounting hole of setting, mounting hole are used in parallel reaction instrument
Reaction tube is installed, setting needs drug to be reacted or chemical reaction product in reaction tube.Parallel test controls external rings
Border is consistent, is studied by the invisible spectro response situation of observing response.Existing parallel reaction instrument includes heating module, cooling
Module, gas path module etc..Heating module for heating, refrigerating module for cooling down or condensing, heating module and refrigerating module it
Between supported using support device such as support plate and support column.Upper cover is arranged in refrigerating module upper seal.Some reactions need
Full of being carried out under inert gas conditions, it is therefore desirable to which extraction examination inner air tube and the device for pouring nitrogen, gas path module connect
Inert gas in gas source is poured reaction tube or by the invisible spectro air of vacuum pump extraction by logical reaction tube.Instead
Answer the feeding device for also setting up on test tube and reaction raw materials being added.
Existing refrigerating module includes cooler pan, and the interior setting of cooler pan is multiple to make the mesoporous that reaction tube passes through, and mesoporous is
The identical through-hole of size.Runner is set around mesoporous, the reaction examination in cold water or other liquid cold source centring hole is led in runner
Pipe is cooled down.Runner originally be set as the annular groove concentric with cooler pan, this structure cooling velocity is slow.Patent
CN107456942A discloses a kind of parallel reaction instrument, and seat of honour side wall is arranged runner, runner to adjacent cooling hole respectively from
Positive, reversed to surround, the runner of this curve is less, more efficient cooling time than the runner of annular.But this mode, phase
The ipsilateral cooling velocity of adjacent reaction tube is inconsistent, and in parallel laboratory test, external condition, which will be consistent, can just be such that experiment ties
Fruit is accurate.Cooling velocity difference can impact result, need a kind of good cooling results and can guarantee that all reaction tubes are cold
But the consistent cooling system of speed.
After reaction, will not sometimes directly take out the reaction tube in parallel reaction instrument, but with hand by cooler pan,
Upper dribbling reaction tube is moved together.Cooler pan smoother needs a kind of anti-sliding stop, convenient hand-held structure.It is cooling
Median pore diameter in disk is greater than reaction tube and needs a kind of mechanism of fastening in order to which reaction tube does not shake during the reaction.
Summary of the invention
The purpose of the utility model is to provide it is a kind of it is low in cost, manufacture is easy to use, one kind for being less likely to be damaged is parallel
React the cooler pan of instrument.
The purpose of this utility model is achieved in that a kind of cooler pan of parallel reaction instrument, and setting is logical thereon
The mesoporous of reaction tube and the chute for cooling down reaction tube in mesoporous are crossed, one end of not set runner, which is arranged, on cooler pan uses
In the carrying groove for picking and placing cooler pan, edge of the cooler pan far from the center of circle is arranged in carrying groove.
Carrying groove is made of three or four finger shape slots disposed in parallel, forms the carrying groove of impression of the hand shape.It is cold
But disk circumference face corresponds to the slot of the position setting thumb shape of finger shape slot.
Along two carrying grooves of cooler pan center symmetric setting on cooler pan.
Being passed around from each mesoporous close to the side in the cooler pan center of circle for uniform flow passage, is arranged connecting passage on cooler pan
Inlet and liquid outlet;Annular groove is set along the position of cooler pan excircle, annular groove is connected to mesoporous and avoids feed liquor
The position of mouth and liquid outlet;Setting compresses the elastic ring of reaction tube on annular groove.
The beneficial effects of the utility model are: one end of not set runner is arranged for picking and placing removing for cooler pan on cooler pan
Slot is transported, cooler pan and upper disk is facilitated to install or dismantle.Also facilitate by after test cooler pan and upper disk and reaction tube together
It is fetched into suitable position observation structure or carries out the experiment of next step.
Detailed description of the invention
Fig. 1 is reaction tube schematic diagram.
Fig. 2 is Fig. 1 explosive view.
Fig. 3 is biexhaust pipe and reaction tube schematic diagram (only showing a biexhaust pipe).
Fig. 4 is tee tube and reaction tube schematic diagram.
Fig. 5 is parallel reaction instrument schematic diagram (omitting gas path module).
Fig. 6 is cooler pan top view.
Fig. 7 is cooler pan bottom view.
Fig. 8 is cooler pan side view.
Fig. 9 is upper disk top view.
Figure 10 is reaction tube embodiment two.
1 it is wherein lower wall, 2 be support column, 3 be cooler pan, 4 be upper disk, 5 be reaction tube, 6 be biexhaust pipe, 7 is threeway
Pipe, 8 be gas source, 9 be vacuum pump, 30 be runner, 31 be seal groove, 32 be mesoporous, 33 be annular groove, 34 be elastic ring, 35 be
Carrying groove, 40 be upper hole, 50 be open end, 51 be branched pipe, 52 be diaphragm seal, 53 be plug sealing mechanism, 54 be that inside is opened
Mouthful end, 55 be sealing ring, 56 be thread cap, 57 be branch's tracheae.
Specific embodiment
As Figure 1-10 shows, a kind of novel parallel reaction instrument, including parallel reaction instrument ontology are set on parallel reaction instrument ontology
Heating module, refrigerating module, reaction tube 5 are set, reaction tube 5 is heated by heating module, cooled down by refrigerating module.
It further include gas path module, gas path module connects the air that reaction tube 5 is used in extraction test tube 5 or to reaction tube 5
Inside it is passed through inert gas, such as nitrogen.
As shown in Fig. 1-2,10, feeding mechanism and ventilation mechanism are provided on the reaction tube 5 of parallel reaction instrument.
Open end 50 is arranged in 5 upper end of reaction tube, below open end 50 setting head end be connected to reaction tube 5, end it is outwardly directed
Branch's nozzle is arranged in branched pipe 51,51 end of branched pipe.The diaphragm seal 52 of branch's nozzle setting sealing branch's nozzle.Open end 50
One end is set and protrudes into plug sealing mechanism 53 inside reaction tube 5.Plug sealing mechanism 53 is moved to 51 other end of branched pipe
Lower section seal the reaction tube space under it;It is sealed always between open end 50 in 53 moving process of plug sealing mechanism.
Plug sealing mechanism 53 and feeding mechanism are provided separately, various to have relatively large space, are simple to manufacture, are assembled simple, precision
It is required that it is low, greatly reduce cost.After charging, do not have to extract syringe needle, that is, salable, such case ratio extraction from diaphragm seal 52
The scheme sealed again after syringe needle, sealing effect are more preferable.And the requirement to diaphragm seal 52 is relatively low, it is only necessary to which it is inserted in syringe needle
It keeps air tight during entering, reduces costs.Pass through the competitiveness for reducing cost, improving product.Diaphragm seal 52 can
Think the material, such as silicone resin etc. at the valve using existing sealing reaction tube, guarantees not leak in fill process
Gas.
Reaction tube 5 is internally located at the lower section setting inner opening end 54 of open end 50;The internally positioned opening of branched pipe 51
Between end 54 and open end 50.Inner opening end 50 is blocked or is unclamped in the movement in reaction tube 5 of plug sealing mechanism 53.It opens
Mouth 50 area of end is not less than the area at inner opening end 54.Reaction tube 5 is located at the diameter below 51 head end of branched pipe greater than it
The diameter of top;Or the diameter of 53 lower end of plug sealing mechanism is less than the diameter of upper end.Here inner opening end can be
One lesser opening is set inside reaction tube 5, is also possible to the pipeline that reaction tube 5 is located at below 51 head end of branched pipe
The inner opening end 54 for the composition that becomes smaller.
Plug sealing mechanism 53 is column structure, is arranged at least one sealing ring 55 on excircle, sealing ring 55 and anti-
It answers and is in close contact between test tube 5.It is preferred that the top position of plug sealing mechanism 53 is arranged in sealing ring 55, in internal open end 54
When opening, 55 position of sealing ring is located at the top of 51 head end of branched pipe, guarantees to feed from branched pipe 51 while sealing
It can be normally carried out.After internal open end 54 is closed, is compressed between sealing ring 55 and reaction tube 5, play secondary seal
Effect.Corrosion-resistant coating, such as tetrafluoro layer is arranged in 55 outer layer of sealing ring.
The hold-down mechanism for making to compress between plug sealing mechanism 53 and inner opening end 54 is set outside plug sealing mechanism 53.
Reaction tube 5 is connect with hold-down mechanism, and hold-down mechanism and reaction tube can be connected between 5 upper end by thread mechanism.It compresses
Mechanism is the thread cap 56 that internal screw thread is arranged in inner wall, the external screw thread of 5 upper end outer wall of reaction tube setting and screw-internal thread fit, plug
Sealing mechanism 53 is connected in thread cap 56 and concentric with thread cap 56 by thread mechanism.Plug sealing mechanism 53 can be four
Fluorine column.Inner opening end 54 is blocked in tetrafluoro column lower end, there is certain flexibility and anticorrosion, there is sealing effect in the case where pressure
Preferably.
Head end is connected to reaction tube 5, end is protruding and and parallel reaction for setting below 5 open end 50 of reaction tube
Branch's tracheae 57 of the gas path module connection of instrument.
The gas path module of parallel reaction instrument can be set in parallel reactor ontology, be integrated in as in the prior art
Upper disk.Also it can be set in the outside of parallel reaction instrument ontology.Gas path module one end connected component tracheae 57, the other end pass through valve
Door is respectively communicated with gas source 8 and vacuum pump 9.In the prior art, gas path module is arranged in parallel reaction instrument body interior.Refrigerating module
Including cooler pan 3, upper cover 4 is set on cooler pan 3.Gas path module is integrated in disk 4.Need special cost of manufacture higher, and
And it can only be used on corresponding parallel reaction instrument.The outside of parallel reaction instrument ontology is arranged in gas path module by the utility model,
The production is simple and convenient, simplifies the manufacture difficulty and cost of disk 4.It is easy for installation and removal, in addition, gas path module can also be used
In other instrument.The mechanism for working normally parallel reaction instrument of gas is additionally provided in parallel reaction instrument ontology, this part is
The prior art is no longer described in detail.
As shown in figure 3, gas path module can be biexhaust pipe 6, the gas source is noble gas source.Biexhaust pipe 6 is experiment
It is the common equipment in room, low in cost.It is provided with valve on multiple branch stubs of biexhaust pipe 6, reaction tube is connected to by pipeline
5.Two parallel long tubes of biexhaust pipe are respectively communicated with inert gas source, such as nitrogen gas tank and vacuum pump 9.It can be same using biexhaust pipe 6
When multiple reaction tubes are evacuated simultaneously or are passed through inert gas simultaneously.If reaction tube there are 12, it is logical to can be set 12
Biexhaust pipe.Bracket is set outside parallel reaction instrument ontology, and biexhaust pipe is arranged on bracket.
As shown in figure 4, gas path module may be tee tube 7, in tee tube 7 setting triple valve control the on-off of gas circuit with
Conversion, branch's tracheae 57 of reaction tube 5 are connected with the supervisor of tee tube 7, and two laterals of tee tube 7 are respectively communicated with very
Sky pump 9 and gas source 8, gas source 8 can be nitrogen ball at this time.One nitrogen ball can meet the nitrogen in a reaction tube 5
Needs.Reaction tube 5 cannot be evacuated simultaneously, can side by side connection vacuum pump pumping, i.e., reaction tube 5 can be single
A use is adapted to the less situation of the reaction tube 5 needed.
As viewed in figures 5-8, the refrigerating module of parallel reaction instrument ontology includes cooler pan 3, is arranged on cooler pan 3 for cooling down
The upper disk 4 for sealing runner is arranged on cooler pan 3 for the runner 30 of reaction tube 5.Distinguish the two sides of the runner 30 of cooler pan 3
Seal groove 31 is set, sealant is set in seal groove 31, upper Pan4Gai makes cooler pan 3 and upper disk 4 be located at runner 30 on sealant
Space sealing between the seal groove 31 of two sides constitutes cooler pan runner sealing mechanism.Existing sealing mechanism is close using O-ring
It seals, must have enough pressure between disk 4 and cooler pan 3 on this sealing means.So stressed mechanism must be applied, than
It is such as connected by screw bolts disk and cooler pan applies pressure.And the application, it is sealed using sealant, pressure must no longer have
Air-proof condition.O-ring is easily damaged under pressure or corrosive environment, to influence sealing effect;Sealant sealing uses
Service life is long, seldom damages within the parallel reactor normal use time.Sealant can be liquid sealant.Or
Common sealant.It can be bolted between cooler pan and upper disk.In the mode of traditional O-ring sealing, bolt must
Must be uniformly distributed, such pressure is just even equal.There is no this limitations for the mode of sealant sealing.
Upper disk 4 is cylindrical type, and setting thereon passes through the upper hole 40 of reaction tube 5, setting and reaction tube 5 on cooler pan 3
The runner 30 around mesoporous 32 is arranged in the corresponding mesoporous 32 in position, mesoporous 32 outside, and runner 30 is uniformly close from each mesoporous 32
The side in the cooler pan center of circle is passed around, and the inlet and liquid outlet of connecting passage 30 are arranged on cooler pan 3.Existing runner 30
The circular mode of centring hole 32 is mostly as follows: runner 30 is passed around from a mesoporous 32 close to the side in the cooler pan center of circle, so
It is passed around afterwards from adjacent mesoporous 32 far from the side in the cooler pan center of circle.This circular mode causes anti-in adjacent mesopores 32
It answers 5 cooling velocity of test tube inconsistent, influences the effect of parallel reaction.The application runner 30 is uniformly from each mesoporous 32 close to cold
But the side in the disk center of circle is passed around, and the flow channel shape and circular mode outside each mesoporous 32 are the same, cooling velocity one
It causes, cooling effect is more stable.And the diameter of cooler pan 3 can do it is smaller,
Can be set annular groove 33 along the position of 3 excircle of cooler pan, annular groove 33 be connected to mesoporous 32 and avoid into
The position of liquid mouth and liquid outlet;Setting compresses the elastic ring 34 of reaction tube on annular groove 33.The diameter of mesoporous 32 is greater than reaction
Test tube 5, reaction tube 5 can shake in it.Reaction tube 5, reaction examination are compressed by the way that elastic ring 34 is arranged on annular groove 33
Pipe will not shake during the experiment.Elastic ring 35 can be had the material of certain elasticity to be made by rubber ring etc..Runner
30 are uniformly passed around from each mesoporous 32 close to the side in the cooler pan center of circle, and runner 30 will not be connected to annular groove 33.
The carrying groove 35 for picking and placing cooler pan 3 is arranged in one end of not set runner 30 on cooler pan 3, and carrying groove 35 is arranged
In edge of the cooler pan 3 far from the center of circle.Cooler pan 3 and upper disk 4 is facilitated to install or dismantle.Also facilitate the reaction after test
Test tube 5 is fetched into suitable position observation structure with cooler pan 3 and upper disk 4 or carries out the experiment of next step.Carrying groove 35 can
To be made of three or four finger shape slots disposed in parallel, the carrying groove 35 of impression of the hand shape is formed.3 circumference of cooler pan
Face corresponds to the slot of the position setting thumb shape of finger shape slot.Along cooler pan center symmetric setting two on cooler pan 3
Carrying groove 35.
Heating module includes lower wall 1, setting lower opening corresponding with reaction tube bottom shape, lower wall 1 and cooling on lower wall 1
The support column 2 of setting support lower wall 1 and cooler pan 3 between disk 3.The heating dish of parallel reaction instrument is placed on magnetic stirring apparatus,
Reaction tube is heated and stirred on magnetic stirring apparatus.These are the prior art there are also remaining mechanism of parallel reactor,
No longer it is described in detail.
When it is implemented, reaction tube 5 is mounted in parallel reaction instrument ontology, tightened with elastic ring 34.Plug is close
Sealing mechanism 53 blocks open end 50, and diaphragm seal 52 seals branched pipe 51.Pass through 9 extraction test tube of vacuum pump according to experiment condition
Air in 53, and nitrogen is poured into reaction tube 5 by gas source 8.Multiple reaction tubes can be given simultaneously using biexhaust pipe 6
5 pumpings or inflation.Balloon inflation can also be evacuated or passed through in turn using tee tube.Indifferent gas is full of in reaction tube 5
After body, chemical reagent is added into reaction tube 5 by diaphragm seal 52 with syringe needle, then plug sealing mechanism 53 moves down stifled
Firmly inner opening end 54, syringe needle extraction.It is reacted by heating or cooling down.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
Although multiple embodiments of the invention have been shown and described above, for those of ordinary skill in the art
For, it is possible to understand that a variety of variations are carried out to these embodiments without departing from the principles and spirit of the present invention, are repaired
Change, replacement and variant, protection scope of the present invention is limited by every claim and its equivalency range.
Claims (5)
1. a kind of cooler pan of parallel reaction instrument, setting thereon reacts examination by the mesoporous of reaction tube and for cooling down in mesoporous
The runner of pipe, it is characterised in that: the carrying groove for picking and placing cooler pan is arranged in one end of not set runner on the cooler pan, removes
Edge of the cooler pan far from the center of circle is arranged in fortune slot.
2. a kind of cooler pan of parallel reaction instrument according to claim 1, it is characterised in that: the carrying groove by three or
Four finger shape slot compositions disposed in parallel, form the carrying groove of impression of the hand shape.
3. a kind of cooler pan of parallel reaction instrument according to claim 2, it is characterised in that: cooler pan circumference face corresponds to hand
The slot of the position setting thumb shape of finger-type shape slot.
4. -3 any a kind of cooler pan of parallel reaction instrument according to claim 1, it is characterised in that: edge on the cooler pan
Two carrying grooves of cooler pan center symmetric setting.
5. -3 any a kind of cooler pan of parallel reaction instrument according to claim 1, it is characterised in that: the uniform flow passage
It is passed around from each mesoporous close to the side in the cooler pan center of circle, the inlet and liquid outlet of connecting passage is set on cooler pan;
Annular groove is set along the position of cooler pan excircle, annular groove is connected to mesoporous and avoids the position of inlet and liquid outlet;
Setting compresses the elastic ring of reaction tube on annular groove.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201822095594.5U CN209379002U (en) | 2018-12-13 | 2018-12-13 | A kind of cooler pan of parallel reaction instrument |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201822095594.5U CN209379002U (en) | 2018-12-13 | 2018-12-13 | A kind of cooler pan of parallel reaction instrument |
Publications (1)
Publication Number | Publication Date |
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CN209379002U true CN209379002U (en) | 2019-09-13 |
Family
ID=67871767
Family Applications (1)
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CN201822095594.5U Active CN209379002U (en) | 2018-12-13 | 2018-12-13 | A kind of cooler pan of parallel reaction instrument |
Country Status (1)
Country | Link |
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CN (1) | CN209379002U (en) |
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2018
- 2018-12-13 CN CN201822095594.5U patent/CN209379002U/en active Active
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