CN209378972U - Parallel reaction instrument cooler pan runner sealing mechanism - Google Patents

Abstract

The utility model provides that a kind of sealing is firm, the simple parallel reaction instrument cooler pan runner sealing mechanism of structure, including cooler pan, and the runner for cooling down reaction tube is arranged on cooler pan, the upper disk for sealing runner is arranged on cooler pan；Seal groove is respectively set in the two sides of the runner of cooler pan, sealant is arranged in seal groove, upper disk cover makes cooler pan and upper disk be located at the space sealing between the seal groove of runner two sides on sealant.It is bolted and compresses between cooler pan and upper disk.The utility model is sealed using sealant, and pressure is no longer the air-proof condition that must have.Sealant sealing service life is long, seldom damages within the parallel reactor normal use time.

Description

Parallel reaction instrument cooler pan runner sealing mechanism

Technical field

The utility model belongs to the reaction kits fields such as chemistry and bio-pharmaceuticals, and in particular to parallel reaction instrument cooler pan stream Road sealing mechanism.

Background technique

Parallel reaction instrument be it is a kind of research and development, test, exploitation used in instrument, can be realized parallel projects reaction, thus Realize short form test, efficiently, the function accurately reacted.The equally distributed mounting hole of setting, mounting hole are used in parallel reaction instrument Reaction tube is installed, setting needs drug to be reacted or chemical reaction product in reaction tube.Parallel test controls external rings Border is consistent, is studied by the invisible spectro response situation of observing response.Existing parallel reaction instrument includes heating module, cooling Module, gas path module etc..Heating module for heating, refrigerating module for cooling down or condensing, heating module and refrigerating module it Between supported using support device such as support plate and support column.Upper cover is arranged in refrigerating module upper seal.Some reactions need Full of being carried out under inert gas conditions, it is therefore desirable to which extraction examination inner air tube and the device for pouring nitrogen, gas path module connect Inert gas in gas source is poured reaction tube or by the invisible spectro air of vacuum pump extraction by logical reaction tube.Instead Answer the feeding device for also setting up on test tube and reaction raw materials being added.

Existing refrigerating module includes cooler pan, and the interior setting of cooler pan is multiple to make the mesoporous that reaction tube passes through, and mesoporous is The identical through-hole of size.Runner is set around mesoporous, the reaction examination in cold water or other liquid cold source centring hole is led in runner Pipe is cooled down.Runner originally be set as the annular groove concentric with cooler pan, this structure cooling velocity is slow.Patent CN107456942A discloses a kind of parallel reaction instrument, and seat of honour side wall is arranged runner, runner to adjacent cooling hole respectively from Positive, reversed to surround, the runner of this curve is less, more efficient cooling time than the runner of annular.But this mode, phase The ipsilateral cooling velocity of adjacent reaction tube is inconsistent, and in parallel laboratory test, external condition, which will be consistent, can just be such that experiment ties Fruit is accurate.Cooling velocity difference can impact result, need a kind of good cooling results and can guarantee that all reaction tubes are cold But the consistent cooling system of speed.

Cooler pan, which needs to seal, guarantees that the coolant liquid of cooling bath will not be revealed.Existing encapsulating method is the two of cooling bath The O-ring sealing of annular is respectively set in side, is compressed between upper disk and cooler pan by structures such as bolts, to compress sealing ring. This encapsulating method needs to provide enough pressing forces to upper disk and cooler pan, guarantees that O-ring is in impaction state, such ability Guarantee sealing effect.Once bolt looseness or pressure are irregular, it be easy to cause leakage.Moreover, O-ring pressure it is bigger and It works with corrosive occasion, is easily damaged, causes to leak.Need a kind of simple, safe, non-damageable sealing structure.

Summary of the invention

Firm, the simple parallel reaction instrument cooler pan runner sealing of structure that the purpose of the utility model is to provide a kind of sealings Mechanism.

The purpose of this utility model is achieved in that a kind of parallel reaction instrument cooler pan runner sealing mechanism, Runner for cooling down reaction tube is set including cooler pan, on cooler pan, the upper disk for sealing runner is set on cooler pan； Seal groove is respectively set in the two sides of the runner of cooler pan, sealant is arranged in seal groove, upper disk cover makes cooler pan on sealant And upper disk is located at the space sealing between the seal groove of runner two sides.Sealant is liquid sealant.

It is bolted and compresses between cooler pan and upper disk.

Upper disk is cylindrical type, and setting thereon passes through the upper hole of reaction tube, and setting is corresponding with upper hole site on cooler pan The runner around mesoporous is arranged in mesoporous, mesoporous outside, and uniform flow passage surround warp from each mesoporous close to the side in the cooler pan center of circle It crosses, the inlet and liquid outlet of connecting passage is set on cooler pan.

The beneficial effects of the utility model are: being sealed using sealant, pressure is no longer the air-proof condition that must have.Sealing Glue sealing service life is long, seldom damages within the parallel reactor normal use time.

Detailed description of the invention

Fig. 1 is reaction tube schematic diagram.

Fig. 2 is Fig. 1 explosive view.

Fig. 3 is biexhaust pipe and reaction tube schematic diagram (only showing a biexhaust pipe).

Fig. 4 is tee tube and reaction tube schematic diagram.

Fig. 5 is parallel reaction instrument schematic diagram (omitting gas path module).

Fig. 6 is cooler pan top view.

Fig. 7 is cooler pan bottom view.

Fig. 8 is cooler pan side view.

Fig. 9 is upper disk top view.

Figure 10 is reaction tube embodiment two.

1 it is wherein lower wall, 2 be support column, 3 be cooler pan, 4 be upper disk, 5 be reaction tube, 6 be biexhaust pipe, 7 is threeway Pipe, 8 be gas source, 9 be vacuum pump, 30 be runner, 31 be seal groove, 32 be mesoporous, 33 be annular groove, 34 be elastic ring, 35 be Carrying groove, 40 be upper hole, 50 be open end, 51 be branched pipe, 52 be diaphragm seal, 53 be plug sealing mechanism, 54 be that inside is opened Mouthful end, 55 be sealing ring, 56 be thread cap, 57 be branch's tracheae.

Specific embodiment

As Figure 1-10 shows, a kind of novel parallel reaction instrument, including parallel reaction instrument ontology are set on parallel reaction instrument ontology Heating module, refrigerating module, reaction tube 5 are set, reaction tube 5 is heated by heating module, cooled down by refrigerating module. It further include gas path module, gas path module connects the air that reaction tube 5 is used in extraction test tube 5 or to reaction tube 5 Inside it is passed through inert gas, such as nitrogen.

As shown in Fig. 1-2,10, feeding mechanism and ventilation mechanism are provided on the reaction tube 5 of parallel reaction instrument. Open end 50 is arranged in 5 upper end of reaction tube, below open end 50 setting head end be connected to reaction tube 5, end it is outwardly directed Branch's nozzle is arranged in branched pipe 51,51 end of branched pipe.The diaphragm seal 52 of branch's nozzle setting sealing branch's nozzle.Open end 50 One end is set and protrudes into plug sealing mechanism 53 inside reaction tube 5.Plug sealing mechanism 53 is moved to 51 other end of branched pipe Lower section seal the reaction tube space under it；It is sealed always between open end 50 in 53 moving process of plug sealing mechanism. Plug sealing mechanism 53 and feeding mechanism are provided separately, various to have relatively large space, are simple to manufacture, are assembled simple, precision It is required that it is low, greatly reduce cost.After charging, do not have to extract syringe needle, that is, salable, such case ratio extraction from diaphragm seal 52 The scheme sealed again after syringe needle, sealing effect are more preferable.And the requirement to diaphragm seal 52 is relatively low, it is only necessary to which it is inserted in syringe needle It keeps air tight during entering, reduces costs.Pass through the competitiveness for reducing cost, improving product.Diaphragm seal 52 can Think the material, such as silicone resin etc. at the valve using existing sealing reaction tube, guarantees not leak in fill process Gas.

Reaction tube 5 is internally located at the lower section setting inner opening end 54 of open end 50；The internally positioned opening of branched pipe 51 Between end 54 and open end 50.Inner opening end 50 is blocked or is unclamped in the movement in reaction tube 5 of plug sealing mechanism 53.It opens Mouth 50 area of end is not less than the area at inner opening end 54.Reaction tube 5 is located at the diameter below 51 head end of branched pipe greater than it The diameter of top；Or the diameter of 53 lower end of plug sealing mechanism is less than the diameter of upper end.Here inner opening end can be One lesser opening is set inside reaction tube 5, is also possible to the pipeline that reaction tube 5 is located at below 51 head end of branched pipe The inner opening end 54 for the composition that becomes smaller.

Plug sealing mechanism 53 is column structure, is arranged at least one sealing ring 55 on excircle, sealing ring 55 and anti- It answers and is in close contact between test tube 5.It is preferred that the top position of plug sealing mechanism 53 is arranged in sealing ring 55, in internal open end 54 When opening, 55 position of sealing ring is located at the top of 51 head end of branched pipe, guarantees to feed from branched pipe 51 while sealing It can be normally carried out.After internal open end 54 is closed, is compressed between sealing ring 55 and reaction tube 5, play secondary seal Effect.Corrosion-resistant coating, such as tetrafluoro layer is arranged in 55 outer layer of sealing ring.

The hold-down mechanism for making to compress between plug sealing mechanism 53 and inner opening end 54 is set outside plug sealing mechanism 53. Reaction tube 5 is connect with hold-down mechanism, and hold-down mechanism and reaction tube can be connected between 5 upper end by thread mechanism.It compresses Mechanism is the thread cap 56 that internal screw thread is arranged in inner wall, the external screw thread of 5 upper end outer wall of reaction tube setting and screw-internal thread fit, plug Sealing mechanism 53 is connected in thread cap 56 and concentric with thread cap 56 by thread mechanism.Plug sealing mechanism 53 can be four Fluorine column.Inner opening end 54 is blocked in tetrafluoro column lower end, there is certain flexibility and anticorrosion, there is sealing effect in the case where pressure Preferably.

Head end is connected to reaction tube 5, end is protruding and and parallel reaction for setting below 5 open end 50 of reaction tube Branch's tracheae 57 of the gas path module connection of instrument.

The gas path module of parallel reaction instrument can be set in parallel reactor ontology, be integrated in as in the prior art Upper disk.Also it can be set in the outside of parallel reaction instrument ontology.Gas path module one end connected component tracheae 57, the other end pass through valve Door is respectively communicated with gas source 8 and vacuum pump 9.In the prior art, gas path module is arranged in parallel reaction instrument body interior.Refrigerating module Including cooler pan 3, upper cover 4 is set on cooler pan 3.Gas path module is integrated in disk 4.Need special cost of manufacture higher, and And it can only be used on corresponding parallel reaction instrument.The outside of parallel reaction instrument ontology is arranged in gas path module by the utility model, The production is simple and convenient, simplifies the manufacture difficulty and cost of disk 4.It is easy for installation and removal, in addition, gas path module can also be used In other instrument.The mechanism for working normally parallel reaction instrument of gas is additionally provided in parallel reaction instrument ontology, this part is The prior art is no longer described in detail.

As shown in figure 3, gas path module can be biexhaust pipe 6, the gas source is noble gas source.Biexhaust pipe 6 is experiment It is the common equipment in room, low in cost.It is provided with valve on multiple branch stubs of biexhaust pipe 6, reaction tube is connected to by pipeline 5.Two parallel long tubes of biexhaust pipe are respectively communicated with inert gas source, such as nitrogen gas tank and vacuum pump 9.It can be same using biexhaust pipe 6 When multiple reaction tubes are evacuated simultaneously or are passed through inert gas simultaneously.If reaction tube there are 12, it is logical to can be set 12 Biexhaust pipe.Bracket is set outside parallel reaction instrument ontology, and biexhaust pipe is arranged on bracket.

As shown in figure 4, gas path module may be tee tube 7, in tee tube 7 setting triple valve control the on-off of gas circuit with Conversion, branch's tracheae 57 of reaction tube 5 are connected with the supervisor of tee tube 7, and two laterals of tee tube 7 are respectively communicated with very Sky pump 9 and gas source 8, gas source 8 can be nitrogen ball at this time.One nitrogen ball can meet the nitrogen in a reaction tube 5 Needs.Reaction tube 5 cannot be evacuated simultaneously, can side by side connection vacuum pump pumping, i.e., reaction tube 5 can be single A use is adapted to the less situation of the reaction tube 5 needed.

As viewed in figures 5-8, the refrigerating module of parallel reaction instrument ontology includes cooler pan 3, is arranged on cooler pan 3 for cooling down The upper disk 4 for sealing runner is arranged on cooler pan 3 for the runner 30 of reaction tube 5.Distinguish the two sides of the runner 30 of cooler pan 3 Seal groove 31 is set, sealant is set in seal groove 31, upper Pan4Gai makes cooler pan 3 and upper disk 4 be located at runner 30 on sealant Space sealing between the seal groove 31 of two sides constitutes cooler pan runner sealing mechanism.Existing sealing mechanism is close using O-ring It seals, must have enough pressure between disk 4 and cooler pan 3 on this sealing means.So stressed mechanism must be applied, than It is such as connected by screw bolts disk and cooler pan applies pressure.And the application, it is sealed using sealant, pressure must no longer have Air-proof condition.O-ring is easily damaged under pressure or corrosive environment, to influence sealing effect；Sealant sealing uses Service life is long, seldom damages within the parallel reactor normal use time.Sealant can be liquid sealant.Or Other common sealant.It can be bolted between cooler pan and upper disk.In the mode of traditional O-ring sealing, spiral shell Bolt must be evenly distributed with, and such pressure is just even equal.There is no this limitations for the mode of sealant sealing.

Upper disk 4 is cylindrical type, and setting thereon passes through the upper hole 40 of reaction tube 5, setting and reaction tube 5 on cooler pan 3 The runner 30 around mesoporous 32 is arranged in the corresponding mesoporous 32 in position, mesoporous 32 outside, and runner 30 is uniformly close from each mesoporous 32 The side in the cooler pan center of circle is passed around, and the inlet and liquid outlet of connecting passage 30 are arranged on cooler pan 3.Existing runner 30 The circular mode of centring hole 32 is mostly as follows: runner 30 is passed around from a mesoporous 32 close to the side in the cooler pan center of circle, so It is passed around afterwards from adjacent mesoporous 32 far from the side in the cooler pan center of circle.This circular mode causes anti-in adjacent mesopores 32 It answers 5 cooling velocity of test tube inconsistent, influences the effect of parallel reaction.The application runner 30 is uniformly from each mesoporous 32 close to cold But the side in the disk center of circle is passed around, and the flow channel shape and circular mode outside each mesoporous 32 are the same, cooling velocity one It causes, cooling effect is more stable.And the diameter of cooler pan 3 can do it is smaller,

Can be set annular groove 33 along the position of 3 excircle of cooler pan, annular groove 33 be connected to mesoporous 32 and avoid into The position of liquid mouth and liquid outlet；Setting compresses the elastic ring 34 of reaction tube on annular groove 33.The diameter of mesoporous 32 is greater than reaction Test tube 5, reaction tube 5 can shake in it.Reaction tube 5, reaction examination are compressed by the way that elastic ring 34 is arranged on annular groove 33 Pipe will not shake during the experiment.Elastic ring 35 can be had the material of certain elasticity to be made by rubber ring etc..Runner 30 are uniformly passed around from each mesoporous 32 close to the side in the cooler pan center of circle, and runner 30 will not be connected to annular groove 33.

The carrying groove 35 for picking and placing cooler pan 3 is arranged in one end of not set runner 30 on cooler pan 3, and carrying groove 35 is arranged In edge of the cooler pan 3 far from the center of circle.Cooler pan 3 and upper disk 4 is facilitated to install or dismantle.Also facilitate the reaction after test Test tube 5 is fetched into suitable position observation structure with cooler pan 3 and upper disk 4 or carries out the experiment of next step.Carrying groove 35 can To be made of three or four finger shape slots disposed in parallel, the carrying groove 35 of impression of the hand shape is formed.On cooler pan 3 along Two carrying grooves 35 of cooler pan center symmetric setting.

Heating module includes lower wall 1, setting lower opening corresponding with reaction tube bottom shape, lower wall 1 and cooling on lower wall 1 The support column 2 of setting support lower wall 1 and cooler pan 3 between disk 3.The heating dish of parallel reaction instrument is placed on magnetic stirring apparatus, Reaction tube is heated and stirred on magnetic stirring apparatus.These are the prior art there are also remaining mechanism of parallel reactor, No longer it is described in detail.

When it is implemented, reaction tube 5 is mounted in parallel reaction instrument ontology, tightened with elastic ring 34.Plug is close Sealing mechanism 53 blocks open end 50, and diaphragm seal 52 seals branched pipe 51.Pass through 9 extraction test tube of vacuum pump according to experiment condition Air in 53, and nitrogen is poured into reaction tube 5 by gas source 8.Multiple reaction tubes can be given simultaneously using biexhaust pipe 6 5 pumpings or inflation.Balloon inflation can also be evacuated or passed through in turn using tee tube.Indifferent gas is full of in reaction tube 5 After body, chemical reagent is added into reaction tube 5 by diaphragm seal 52 with syringe needle, then plug sealing mechanism 53 moves down stifled Firmly inner opening end 54, syringe needle extraction.It is reacted by heating or cooling down.

Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, all should be considered as described in this specification.

Although multiple embodiments of the invention have been shown and described above, for those of ordinary skill in the art For, it is possible to understand that a variety of variations are carried out to these embodiments without departing from the principles and spirit of the present invention, are repaired Change, replacement and variant, protection scope of the present invention is limited by every claim and its equivalency range.

Claims (4)

1. a kind of parallel reaction instrument cooler pan runner sealing mechanism, including cooler pan, setting is for cooling reaction examination on cooler pan The upper disk for sealing runner is arranged on cooler pan for the runner of pipe；It is characterized by: the two sides of the runner of the cooler pan are distinguished Seal groove is set, sealant is set in seal groove, upper disk cover makes cooler pan and upper disk be located at the close of runner two sides on sealant Space sealing between sealing groove.

2. parallel reaction instrument cooler pan runner sealing mechanism according to claim 1, feature is being: the sealant is Liquid sealant.

3. parallel reaction instrument cooler pan runner sealing mechanism according to claim 1 or claim 2, it is characterised in that: the cooler pan It is bolted and compresses between upper disk.

4. parallel reaction instrument cooler pan runner sealing mechanism according to claim 1 or claim 2, it is characterised in that: the upper disk is Cylindrical type, thereon setting pass through the upper hole of reaction tube, setting mesoporous corresponding with upper hole site on cooler pan, are arranged outside mesoporous Around the runner of mesoporous, being passed around from each mesoporous close to the side in the cooler pan center of circle for uniform flow passage is arranged on cooler pan The inlet and liquid outlet of connecting passage.