CN209316045U - Multipole bidirectional high-pressure steep-sided pulse discharge system - Google Patents
Multipole bidirectional high-pressure steep-sided pulse discharge system Download PDFInfo
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- CN209316045U CN209316045U CN201721319618.XU CN201721319618U CN209316045U CN 209316045 U CN209316045 U CN 209316045U CN 201721319618 U CN201721319618 U CN 201721319618U CN 209316045 U CN209316045 U CN 209316045U
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Abstract
The utility model provides a kind of multipole bidirectional high-pressure steep-sided pulse discharge system, including control terminal, high-pressure modular, pulse generation module, electrode combination control module and at least two discharge electrode needles, control terminal controls high-pressure modular, pulse generation module and electrode combination control module, pulse generation module generates positive and negative pulse, discharge electrode needle is connect with electrode combination control module, the discharge electrode needle continuous checker electric discharge of positive and negative anodes between electrode two-by-two in discharge process.The bipolar pulsed discharge is realized between the utility model discharge electrode needle, effective irreversible electric field is made to wrap up tumor tissues as far as possible, is reduced ablation blind area, is enhanced the validity for the treatment of plan.
Description
Technical field
The utility model belongs to the medical apparatus and instruments technical field for the treatment of tumour, more particularly, to a kind of two-way height of multipole
Press steep-sided pulse discharge system.
Background technique
Irreversible electroporation (IRE) is the emerging technology in relation to tumour non-thermal ablation.This technology is sent out by electrode
It send one group of high electric field pulse to form electric field in the tissue, makes cell membrane that irreversible electroporation occur, so that tumour cell withers
It dies.
Irreversible electroporation (IRE) has become the emerging gimmick of non-heat cure of reply tumour and other non-cancer pathology.
This scheme passes through the electrode for being implanted directly into or being placed on around pathological tissues and transmits a series of short and strong electric pulses, in electrode
Between form electric field, change the membrane potential of cell membrane, once membrane potential reaches threshold value, just will form electricity on cell membrane and wear
Hole, as electric field continues to increase, it will lead to the irreversible electroporation of cell, make apoptosis.Simultaneously as steep-sided pulse is made
Extremely short (microsecond rank) with the time, the fuel factor generated often can be ignored, and will not generate thermal damage to tissue.
In the test of previous unidirectional pulse, a phenomenon, after discharge, the anode (anode) of electrode needle are often found
Nigrescence degree is apparently higher than the cathode (cathode) of electrode needle, i.e. the degree of oxidation of anode is higher than cathode.According to electrode discharge process
It can know, voltage is directed toward low potential direction by high potential, and during discharge, anode voltage is significantly larger than cathode.In electric field point
In terms of cloth, when electrode discharges within the organization, similar to the magnetic induction line of magnet NS interpolar, electric field formed within the organization from anode to
The netted region of discharge of cathode.Effective ablation areas wraps up electrode needle and in mesh-like area to external diffusion centered on electrode needle,
Electric field is most strong at the center of electrode needle, and surrounding electric field intensity gradually decays.According to experimental phenomena, the degree of oxidation of anode is obviously high
In cathode, at the same according to ablation of tissue effect after electric discharge from the point of view of, anode electrode tissue necrosis degree is apparently higher than cathode.Supposition can
Know during discharge, anode electric field is much higher than cathode.That is electric field feature that uneven distribution is presented within the organization.It is controlled in clinic
In treatment, since electric field strength is non-uniform Distribution within the organization, results in clinical treatment and occur close to the cell of anode
Over-discharge treatment, and there is the phenomenon that incomplete treatment close to the cell of cathode.
Meanwhile the irreversible electroporation device of tradition, usually only have two electrodes, i.e., can only be discharged mould using bipolar electrode
Formula, larger to tumor tissues or irregular situation, high voltage electric field can not be accomplished effectively to cover, this will lead to ablation be not thorough or
It needs that electric discharge is repeated several times in clinic and can be only achieved desired effect.
Therefore it needs to explore an effective therapeutic equipments, effectively irreversible electric field is on the one hand covered into entire lesion region,
High pressure steep-sided pulse is set to form equally distributed electric field in tumor tissues simultaneously.This is by the strong irreversible electroporation technology of promotion
Application in clinic.
Summary of the invention
In view of this, the utility model is directed to a kind of multipole bidirectional high-pressure steep-sided pulse discharge system, it is above-mentioned to solve
Technical problem.
In order to achieve the above objectives, the technical solution of the utility model is achieved in that
Multipole bidirectional high-pressure steep-sided pulse discharge system, including control terminal, high-pressure modular, pulse generation module, electrode combination
Control module and at least two discharge electrode needles, control terminal control high-pressure modular, pulse generation module and electrode combination and control mould
Block, pulse generation module generate positive and negative pulse, and discharge electrode needle connect with electrode combination control module, discharges in discharge process
The electrode needle continuous checker electric discharge of positive and negative anodes between electrode two-by-two.
Further, the discharge voltage parameter between two discharge electrode needles of electric discharge is 1500V/CM.
Further, electrode combination control module includes that the high-voltage positive electrode connecting respectively with pulse generation module and high pressure are negative
Pole, discharge electrode needle are arranged in parallel, and discharge electrode needle passes through the switch of arranged on left and right sides respectively and high-voltage positive electrode and high voltage negative connect
It connects.
Further, the quantity of discharge electrode needle is two or three, and the distance between two discharge electrode needles are
1.5cm, voltage between the two are 2250V.
Further, the quantity of the discharge electrode needle is three or four or five, corresponding discharge electrode needle
At equilateral triangle, square arrangement, isosceles trapezoid distribution, the distance between every two discharge electrode needle is 1.5cm, electric discharge electricity
Voltage between the needle of pole is 2250V.
Further, the quantity of the discharge electrode needle is five, and five discharge electrode needles are distributed at regular pentagon, every two
The distance between a discharge electrode needle is 1.7cm, and the voltage between discharge electrode needle is 2550V.
Further, the quantity of the discharge electrode needle is six, and it is 1.5cm's that the arrangement of discharge electrode needle, which is divided into spacing,
Rectangle or spacing are the rectangle of 1cm, and the voltage between corresponding discharge electrode needle is 2550V, 1500V.
Further, it is connected between control terminal and high-pressure modular by isolation circuit.
Compared with the existing technology, multipole bidirectional high-pressure steep-sided pulse discharge system described in the utility model has following excellent
Gesture:
(1) the bipolar pulsed discharge is realized between the utility model discharge electrode needle, make effective irreversible electric field as far as possible
Tumor tissues are wrapped up, ablation blind area is reduced, enhances the validity for the treatment of plan；
(2) the utility model uses multiple electrodes the bipolar pulsed discharge, and in treatment region setting, high pressure steep-sided pulse is in group
The interior netted region of discharge of formation is knitted, effective irreversible electric field is made to cover tumor tissues as far as possible, reduces ablation blind area, enhancing is controlled
Treat the validity of plan；
(3) the utility model is designed with cloth needle plans, and doctor is by the parameter input control end of tumour, and control terminal is certainly
It is dynamic to carry out cloth needle plan design, and corresponding treatment plan is shown over the display, including cloth aciculiform shape, voltage and electrode needle number
Amount, provides reference for medical treatment, has saved the time, while improving surgical effect；
(4) charging method of the utility model promotes electricity using positive negative pulse stuffing alternation method is discharged in group or between group
Field being uniformly distributed in tumor tissues, ablation caused by avoiding because of non-uniform electric are not thorough or need to be repeated several times and put
Electricity.
Detailed description of the invention
The attached drawing for constituting a part of the utility model is used to provide a further understanding of the present invention, this is practical new
The illustrative embodiments and their description of type are not constituteed improper limits to the present invention for explaining the utility model.?
In attached drawing:
Fig. 1 is the operation principle schematic diagram of the utility model embodiment；
Fig. 2 is the cloth needle construction schematic diagram of two electrode needles described in the utility model embodiment；
Fig. 3 is the cloth needle construction schematic diagram of three electrode needles described in the utility model embodiment；
Fig. 4 is the cloth needle construction schematic diagram of four electrode needles described in the utility model embodiment；
Fig. 5 is a kind of cloth needle construction schematic diagram of five electrode needles described in the utility model embodiment；
Fig. 6 is another cloth needle construction schematic diagram of five electrode needles described in the utility model embodiment；
Fig. 7 is a kind of cloth needle construction schematic diagram of six electrode needles described in the utility model embodiment；
Fig. 8 is another cloth needle construction schematic diagram of six electrode needles described in the utility model embodiment；
Fig. 9 is positive negative pulse stuffing alternating schematic diagram between group described in the utility model embodiment；
Figure 10 is electrode combination control module structural schematic diagram described in the utility model embodiment；
Figure 11 is treatment system control flow chart described in the utility model embodiment；
Figure 12 is output signal isolates circuit diagram of the control terminal described in the utility model embodiment to high-pressure modular；
Figure 13 is input signal isolates circuit diagram of the high-pressure modular described in the utility model embodiment to control terminal.
Description of symbols:
1, first electrode；2, second electrode；3, third electrode；4, the 4th electrode；5, the 5th electrode；6, the 6th electrode；
701, first switch；702, second switch；703, third switchs；704, the 4th switch；705, the 5th switch；706, it the 6th opens
It closes；707, the 7th switch；708, the 8th switch；709, the 9th switch；710, the tenth switch；711, the 11st switch；712,
12 switches；801, high-voltage positive electrode；802, high voltage negative.
Specific embodiment
It should be noted that in the absence of conflict, the feature in the embodiments of the present invention and embodiment can
To be combined with each other.
In the description of the present invention, it should be understood that term " center ", " longitudinal direction ", " transverse direction ", "upper", "lower",
The orientation or positional relationship of the instructions such as "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is
It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of describing the present invention and simplifying the description, rather than indicate
Or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot understand
For limitations of the present invention.In addition, term " first ", " second " etc. are used for description purposes only, and should not be understood as indicating
Or it implies relative importance or implicitly indicates the quantity of indicated technical characteristic." first ", " second " etc. are defined as a result,
Feature can explicitly or implicitly include one or more of the features.It is in the description of the present invention, unless another
It is described, the meaning of " plurality " is two or more.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified
Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally
Connection；It can be mechanical connection, be also possible to be electrically connected；Can be directly connected, can also indirectly connected through an intermediary,
It can be the connection inside two elements.For the ordinary skill in the art, on being understood by concrete condition
State the concrete meaning of term in the present invention.
The utility model will be described in detail below with reference to the accompanying drawings and embodiments.
As shown in Figure 1, multipole bidirectional high-pressure steep-sided pulse discharge system, including control terminal, high-pressure modular, pulse generation mould
Block, electrode combination control module and at least two discharge electrode needles, control terminal control high-pressure modular, pulse generation module and electrode
Combined control module, discharge electrode needle are connect with electrode combination control module.To reach effective ablation, local voltage mistake is avoided
It is high.Discharge voltage between two discharge electrode needles of electric discharge executes in the way of 1500V/CM.It is minimum to form discharge loop
Discharge electrode needle quantity be 2.Electric discharge forms effective ablation areas to be influenced by discharge electrode needle quantity, i.e., different electric discharge electricity
Pole needle quantity, cloth aciculiform shape will form different region of discharges.
The arragement construction and quantity of discharge electrode needle are determined according to target tumor tissue profile and volume, discharge electrode
The quantity of needle is number of probes needed for needing sufficiently to cover ablation target tissue, and finally determines that each probe is in target or all
Ablation range is enclosed, and then obtains cloth needle construction to reach enough target ablation area sizes.It melts voltage and selects 1500V/cm.
Effective ablation areas is similar to magnetic field centered on discharge electrode needle, in the mesh-like area of package discharge electrode, electric field at center
Most strong, surrounding electric field intensity gradually decays.According to different discharge positions and cloth aciculiform shape, which can accordingly occur
Variation.
The arragement construction that discharge electrode needle quantity is two, as shown in Fig. 2, showing in Fig. 2 for bipolar electrode electric discharge ablation areas
It is intended to, double probe arrays are the basic modules of all Multi probe configurations.The spacing of two discharge electrode needles is 1.5cm, and voltage is
2250V.Effective ablation areas cross section is approximate Double ellipse.
The arragement construction that Fig. 3 discharge electrode needle quantity is three, the arrangement of three needles are triangle.The side length of triangle is
15mm, discharge electrode is to respectively 1-2, and 2-3, the distance between 1-3. every two electrode needle is 1.5cm, so between two electrodes
Discharge voltage be 2250V.Effective ablation areas cross section is approximate ellipsoidal region.
Fig. 4 is the arragement construction that discharge electrode needle quantity is four, and the arrangement of discharge electrode needle is square.Discharge electrode
To respectively 1-2,2-3,3-4,1-4.Spacing between edge every two adjacent electrode is 1.5cm, discharge voltage 2250V,
Effective ablation areas cross section is approximate circle.
Fig. 5 is five electrode discharge ablation areas schematic diagrames, and the arrangement of discharge electrode needle is regular pentagon.Discharge electrode to point
It Wei not 1-2,2-3,3-4,4-5,1-5.Spacing between every two discharge electrode needle is 1.7cm, and each discharge electrode needle is from five
The distance at side shape center is 1.5cm, and discharge voltage is 2550V (1.7CM*1500V/CM=2550V).Effective ablation areas is horizontal
Section is approximately round.
Fig. 6 is another five electrode discharge ablation areas schematic diagrames, the arrangement of five electrodes be it is trapezoidal, trapezoidal top is two
Electrode is three electrodes below.Discharge electrode is to respectively 1-2,2-3,3-4,4-5,1-5.Spacing between every two electrode
For 1.5cm, discharge voltage 2250V.Effective ablation areas cross section is approximate ellipsoidal.
Fig. 7 and Fig. 8 is six electrode discharge ablation areas schematic diagrames.The arrangement of electrode is divided into the rectangle of 3.0cm × 1.5cm
With two kinds of forms of rectangle of 2.0cm × 1.0cm.Discharge electrode is to respectively 1-2,2-3,3-4,4-5,5-6,1-6.If selecting
Fig. 7 cloth needle mode, every two electrode spacing 1.5cm, then discharge voltage is 2250V；If selecting Fig. 8 cloth needle mode, every two electricity
Interpolar is away from for 1.0cm, then the discharge voltage between every two electrode is 1500V.Since probe spacing is different in the case of two kinds,
Discharge voltage between two electrodes is different, so the size of ablation areas is also different.Effective ablation areas cross section is approximate ellipse
It is round.
Pulse generation module can partially be implemented by digital circuit, analog circuit, firmware software or combinations thereof, also implement
For the integrated circuit of specific purpose, such as it is made of FPGA (field programmable gate array) or ASIC (dedicated integrated).Pulse produces
Multi-electrode two-way discharge may be implemented in the diphasic pulse that raw module generates, that is, positive and negative anodes are not between electrode two-by-two in discharge process
Disconnected checker.Discharge mode has two-way discharge two ways between the interior two-way discharge of group and group.
Bidirectional pulse is exactly that pulse generation module generates forward and reverse successively alternate pulse in group.
As shown in figure 9, it is positive electric discharge, a next set of pulses that two-way discharge, which is whole pulses in one group, between group
It is reverse phase electric discharge, repeats this process later.Two-way discharge electrode group with the mode of traditional unidirected discharge between group
Control module is closed to complete.Its main embodiment are as follows: on the basis of traditional unidirected discharge mode, in the automatic control of control terminal
Under system, the positive and negative alternating discharge between different moments operation electrode combination control module achievees the purpose that group.
Figure 10 is forward and reverse pulsed electrode combined control module structural schematic diagram between group.Electrode combination control module includes
High-voltage positive electrode 801 and high voltage negative 802, discharge electrode needle are arranged in parallel, discharge electrode needle pass through respectively it is left and right two switch with
High-voltage positive electrode 801 and high voltage negative 802 connect.When discharge electrode needle selects six, first electrode 1 and high-voltage positive electrode 801 it
Between connected by first switch 701, connected between first electrode 1 and high voltage negative 802 by second switch 702, second electrode 2
It is connect between high-voltage positive electrode 801 by third switch 703, passes through the 4th switch between second electrode 2 and high voltage negative 802
704 connections, are connected between third electrode 3 and high-voltage positive electrode 801 by the 5th switch 705, third electrode 3 and high voltage negative 802
Between connected by the 6th switch 706, by the connection of the 7th switch 707 between the 4th electrode 4 and high-voltage positive electrode 801, the 4th is electric
It is connected between pole 4 and high voltage negative 802 by the 8th switch 708.It is opened between 5th electrode 5 and high-voltage positive electrode 801 by the 9th
709 connections are closed, are connected between the 5th electrode 5 and high voltage negative 802 by the tenth switch 710.6th electrode 6 and high-voltage positive electrode
It is connected between 801 by the 11st switch 711, is connected between the 6th electrode 6 and high voltage negative 802 by the 12nd switch 712.
Set of pulses number is such as set as five, first group of ten pulses are that first electrode 1 is anode, second electrode 2
It discharges for the mode of cathode, second group of ten pulse is that first electrode 1 is cathode, and second electrode 2 is that the mode of anode is discharged.Its
It is that first switch 701 and the conducting of the 4th switch 704, others switch are disconnected at first group that electrode combination control module, which executes logic,
It opens, first electrode 1 is anode at this time, and second electrode 2 is cathode, and current direction is from first electrode 1 to second electrode 2；It is sending out
Second switch 702 and third switch 703 are connected when sending the second group pulse, other switches disconnect, and first electrode 1 is cathode at this time,
Second electrode 2 is anode, and current direction is from second electrode 2 to first electrode 1；It is discharged completely with this recursion to discharge electrode needle
It completes.
Between multi-electrode group in forward and reverse electric discharge, between discharge electrode needle two-by-two, multi-electrode can be realized by above-mentioned principle
The bipolar pulsed discharge between group.Such as selecting number of poles is 6 groups, and electrode cloth needle is rectangle (see Fig. 8), then discharge electrode is to respectively
Totally 12 kinds of 1-2,2-3,3-4,4-5,5-6,1-6,2-1,3-2,4-3,5-4,6-5,6-1.Every group pulse has positive and negative electrode mutual
The case where changing, if 1-2 indicates that first electrode 1 is anode, second electrode 2 is that the mode of cathode is discharged, and 2-1 indicates first electrode
1 is cathode, and second electrode 2 is that the mode of anode is discharged.It is consistent that its switch conduction disconnects the above-mentioned statement of logical AND.
Figure 11 is treatment system control flow chart, and user interface can be inputted, and user interface passes the signal of input
Control terminal is passed, control terminal can be made of microprocessors such as single-chip microcontroller, DSP, and pulse generation module can choose CPLD unit,
CPLD unit is programmable CPLD chip (being existing module, program is voluntarily to write).It is mono- by CPLD under control terminal control
Member generates sequential logic, i.e. generation pulse signal, for controlling the opening and closing of IGBT；When base potential B is relative to emitter potential E
When being high, IGBT is connected, and when base potential B is identical as emitter potential E current potential, IGBT ends.After IGBT conducting,
Switch in conjunction with electrode combination control module, at the electrode both ends of different moments conducting 1 to the 6th electrode 6 of first electrode
Generate positive negative pulse stuffing.
Communication isolation circuit figure of the Figure 12 and Figure 13 between control terminal and high-pressure modular uses the general serial ports side SCI
Formula communication, is divided into two signal wire PCT and PCR, and PCT is output signal line, and PCR is input signal cable, photoelectrical coupler PC1 and
Photoelectrical coupler PC3 is light every module, photoelectrical coupler PC1 and the optional model 6N137 of photoelectrical coupler PC3, mainly
Effect is to carry out Phototube Coupling to signal, to reduce interference of the high-pressure section to controller.
Figure 12 be control terminal and high-pressure modular communication output signal isolates circuit diagram, one end of the 16th resistance R16 with
The connection of PCT signal wire, the other end of the 16th resistance R16 are connect with the anode of first diode DM1, first diode DM1's
Cathode meets power supply DVCC5, and the 32nd capacitor C32 is in parallel with first diode DM1.32nd capacitor C32 and the one or two pole
The connecting node of pipe DM1 anode is connect with 3 feet of photoelectrical coupler PC1, and the 32nd capacitor C32 and first diode DM1 are negative
The connecting node of pole is connect with 2 feet of photoelectrical coupler PC1.5 feet of photoelectrical coupler PC1 are grounded, and the 6 of photoelectrical coupler PC1
Foot is connect by first resistor RA1 with power supply EVCC5, and 7 feet of photoelectrical coupler PC1 pass through second resistance RMD and power supply EVCC5
Connection, 8 feet of photoelectrical coupler PC1 are connect with power supply EVCC5.6 feet of photoelectrical coupler PC1 are also with the first phase inverter U10D's
The connection of 9 feet, 8 feet of the first phase inverter U10D are connect with 5 feet of the second phase inverter U10C, 6 feet and height of the second phase inverter U10C
Die block connection.The model 74HC14 of first phase inverter U10D and the second phase inverter U10C.
Figure 13 is isolates circuit diagram of the high-pressure modular to control terminal input signal, the signal returned from high-pressure modular and third
3 feet of phase inverter U10B connect, and 4 feet of third phase inverter U10B are connect with 11 feet of the 4th phase inverter U10E, the 4th phase inverter
10 feet of U10E are connect with one end of the 18th resistance R18, and the other end of the 18th resistance R18 and the second diode DMB are just
Pole connection.34th capacitor C34 is in parallel with the second diode DMB, and the 34th capacitor C34 and the second diode DMB's is negative
The connecting node of pole is connect with 2 feet of power supply EVCC5 and photoelectrical coupler PC3 respectively, the 34th capacitor C34 and the two or two pole
The connecting node of the anode of pipe DMB is connect with 3 feet of photoelectrical coupler PC3.5 feet of photoelectrical coupler PC3 are grounded, photoelectric coupling
6 feet of device PC3 and the signal input part of control terminal connect, and 6 feet of photoelectrical coupler PC3 also connect with one end of 3rd resistor RA3
It connects, the other end of 3rd resistor RA3 is connect with power supply DVCC5, and 7 feet of photoelectrical coupler PC3 pass through the 4th resistance RMB and power supply
DVCC5 connection.8 feet of photoelectrical coupler PC3 are connect with power supply DVCC5.
Working principle of the utility model is:
In clinical application, it after doctor has determined the shape and volume of tumor tissues, then can be inputted by user interface
The parameter of tumour, the quantity and distributed architecture of discharge electrode needle corresponding with tumor parameters are automatically generated in control terminal, and doctor is defeated
After entering tumor size parameter, the treatment plan comprising information such as number of electrodes, cloth aciculiform shape, pulse parameters is generated in control terminal,
The treatment plan that doctor generates according to system selects corresponding quantity and electrode needle to combine, and control terminal controls pulse generation module
Corresponding pulse output control is executed, control terminal coordination electrode combined control module makes discharge electrode needle discharge, it is ensured that
With the ablation of irreversible electroporation in entire target area.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
Within the spirit and principle of utility model, any modification, equivalent replacement, improvement and so on should be included in the utility model
Protection scope within.
Claims (8)
1. multipole bidirectional high-pressure steep-sided pulse discharge system, it is characterised in that: including control terminal, high-pressure modular, pulse generation module,
Electrode combination control module and at least two discharge electrode needles, control terminal control high-pressure modular, pulse generation module and electrode group
Control module is closed, pulse generation module generates positive and negative pulse, and discharge electrode needle connect with electrode combination control module, discharged
The discharge electrode needle continuous checker electric discharge of positive and negative electrode between electrode two-by-two in journey.
2. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: two electric discharges of electric discharge
Discharge voltage parameter between electrode needle is 1500V/CM.
3. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: electrode combination controls mould
Block includes the high-voltage positive electrode (801) connecting respectively with pulse generation module and high voltage negative (802), and discharge electrode needle parallel connection is set
It sets, the switch that discharge electrode needle passes through arranged on left and right sides respectively is connect with high-voltage positive electrode (801) and high voltage negative (802).
4. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: the number of discharge electrode needle
Amount is two or three, and the distance between two discharge electrode needles are 1.5cm, and voltage between the two is 2250V.
5. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: the discharge electrode needle
Quantity be three or four or five, corresponding discharge electrode needle is at equilateral triangle, square arrangement, isosceles trapezoid
Distribution, the distance between every two discharge electrode needle are 1.5cm, and the voltage between discharge electrode needle is 2250V.
6. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: the discharge electrode needle
Quantity be five, five discharge electrode needles are distributed at regular pentagon, the distance between every two discharge electrode needle be 1.7cm,
Voltage between discharge electrode needle is 2550V.
7. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: the discharge electrode needle
Quantity be six, the arrangement of discharge electrode needle is divided into the rectangle that spacing is 1.5cm or the rectangle that spacing is 1cm, accordingly
Voltage between discharge electrode needle is 2550V, 1500V.
8. multipole bidirectional high-pressure steep-sided pulse discharge system according to claim 1, it is characterised in that: control terminal and high pressing mold
It is connected between block by isolation circuit.
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| CN201721319618.XU CN209316045U (en) | 2017-10-12 | 2017-10-12 | Multipole bidirectional high-pressure steep-sided pulse discharge system |
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| CN201721319618.XU CN209316045U (en) | 2017-10-12 | 2017-10-12 | Multipole bidirectional high-pressure steep-sided pulse discharge system |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186108A (en) * | 2017-10-12 | 2018-06-22 | 天津市鹰泰利安康医疗科技有限责任公司 | Multipole bidirectional high-pressure steep-sided pulse discharge system and charging method |
| CN112998849A (en) * | 2021-02-08 | 2021-06-22 | 南京航空航天大学 | Microwave conformal ablation method based on multi-needle combination |
| CN113768612A (en) * | 2021-07-30 | 2021-12-10 | 苏州艾科脉医疗技术有限公司 | High-voltage transmitting circuit for catheter and ablation tool |
| US11786300B2 (en) | 2021-04-07 | 2023-10-17 | Btl Medical Technologies S.R.O. | Pulsed field ablation device and method |
| US11896298B2 (en) | 2021-07-06 | 2024-02-13 | Btl Medical Development A.S. | Pulsed field ablation device and method |
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2017
- 2017-10-12 CN CN201721319618.XU patent/CN209316045U/en active Active
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186108A (en) * | 2017-10-12 | 2018-06-22 | 天津市鹰泰利安康医疗科技有限责任公司 | Multipole bidirectional high-pressure steep-sided pulse discharge system and charging method |
| CN112998849A (en) * | 2021-02-08 | 2021-06-22 | 南京航空航天大学 | Microwave conformal ablation method based on multi-needle combination |
| US11786300B2 (en) | 2021-04-07 | 2023-10-17 | Btl Medical Technologies S.R.O. | Pulsed field ablation device and method |
| US11832785B2 (en) | 2021-04-07 | 2023-12-05 | Btl Medical Development A.S. | Pulsed field ablation device and method |
| US11896298B2 (en) | 2021-07-06 | 2024-02-13 | Btl Medical Development A.S. | Pulsed field ablation device and method |
| CN113768612A (en) * | 2021-07-30 | 2021-12-10 | 苏州艾科脉医疗技术有限公司 | High-voltage transmitting circuit for catheter and ablation tool |
| WO2023006111A1 (en) * | 2021-07-30 | 2023-02-02 | 苏州艾科脉医疗技术有限公司 | High-voltage transmitting circuit for catheter, and ablation tool |
| CN113768612B (en) * | 2021-07-30 | 2023-12-22 | 苏州艾科脉医疗技术有限公司 | High voltage transmitting circuit for catheter and ablation instrument |
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Effective date of registration: 20220311 Address after: 201804 room 1002-3, room 1002-5 and room 1006-2, floor 10, No. 1112 Hanggui Road, Anting Town, Jiading District, Shanghai Patentee after: Shanghai Yuanshan Medical Technology Co.,Ltd. Address before: 300384 2-2-208401-403, No. 11, Haitai development Fourth Road, Huayuan Industrial Zone (outside the ring), high tech Zone, Binhai New Area, Tianjin Patentee before: TIANJIN INTELLIGENT HEALTH Co.,Ltd. |