CN215839437U - Single-needle nanosecond pulse treatment electrode - Google Patents

Single-needle nanosecond pulse treatment electrode Download PDF

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Publication number
CN215839437U
CN215839437U CN202122134297.9U CN202122134297U CN215839437U CN 215839437 U CN215839437 U CN 215839437U CN 202122134297 U CN202122134297 U CN 202122134297U CN 215839437 U CN215839437 U CN 215839437U
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needle
electrode
cathode sleeve
insulating coating
nanosecond
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王昱博
殷胜勇
黄赫辰
高星星
周原
王帅
周琳
郑树森
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Zhejiang University ZJU
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Zhejiang University ZJU
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Abstract

The utility model discloses a single-needle nanosecond pulse treatment electrode, which comprises: the anode electrode needle comprises a needle body and a needle point fixed at the bottom of the needle body; the cathode sleeve is sleeved outside the needle body, and the outer wall of the cathode sleeve is divided into an insulating covering section and an exposed section; the first insulating coating is distributed between the needle body and the cathode sleeve; a second insulating coating covering the insulating cover section; the third insulating coating is distributed between the lower end of the cathode sleeve and the upper end of the needle point; the holding part is fixed at the upper ends of the cathode sleeve and the anode electrode needle; and the tail plug is detachably inserted on the holding part and is provided with two electrode connectors which are respectively and electrically connected with the anode electrode needle and the cathode sleeve. The single-needle nanosecond pulse treatment electrode provided by the utility model avoids the problem that the treatment effect is influenced because the traditional multi-needle treatment electrodes are difficult to be parallel to each other, reduces the operation difficulty, reduces the pain of a patient, improves the safety and has good clinical application prospect.

Description

Single-needle nanosecond pulse treatment electrode
Technical Field
The utility model relates to the field of pulse tumor ablation treatment, in particular to a single-needle nanosecond pulse treatment electrode.
Background
Nanosecond pulse is originated from a high-power electromagnetic weapon technology, is a high-voltage pulse electric field with the pulse width at a nanosecond level, is used as a novel non-thermal tumor ablation treatment means in recent years, and shows good treatment prospects in various tumors. The nanosecond pulse can compress tens of thousands of volts of electric field energy into ultra-short pulse of one billionth of seconds to carry out successive shooting attack on the tumor, generate special cell effect, penetrate through a membrane to enter a nucleus, selectively attack and divide vigorously tumor cells, simultaneously kill and kill the cells without joule heat, can effectively protect structures such as blood vessels, bile ducts, nerves and the like, and particularly has important value in the field of liver cancer treatment on the treatment of liver cancer with complex structures such as adjacent hepatic portal, blood vessels, bile ducts and the like.
At present, the nanosecond pulse is clinically mature in research direction of skin tumors represented by melanoma, due to shallow position surface, needles of electrodes are distributed at multiple electrode needle matrix points, the length of the electrode needles is short, and related electrode needles are commercially available. However, for deep tumors represented by liver cancer, a longer electrode needle must be used to reach the lesion for ablation, and the ablation schemes are divided into the following two types: 1. directly using an electrode needle to ablate tumors under an open abdominal operation or a laparoscope; 2. under the guidance of ultrasonic wave, the electrode needle is punctured percutaneously to directly reach the tumor focus for ablation. The former has larger operation trauma, is almost the same as the tumor resection operation, and can not embody the minimally invasive advantage of the nanosecond pulse treatment, so the percutaneous puncture ablation is a better scheme for the nanosecond pulse treatment of the deep tumor.
In practical application, nanosecond pulse ablation of tumor needs at least two electrodes, one anode and one cathode, and for larger tumor, more electrodes may need to be inserted, and the electrodes are alternately used as the anode or the cathode during ablation. According to the electric field distribution principle, when two electrodes are completely parallel, the ablation range and effect can be maximized, but in the actual operation process, the two electrodes which are inserted successively are difficult to ensure to be parallel to each other, so that the tumor ablation effect of the nanosecond pulse is difficult to fully exert.
In order to solve the above problems, methods such as fixing the needle insertion direction by adding a mold and using a plate electrode have been adopted. The increase of the mould can ensure that the electrode needle is more parallel, but also fixes the needle inserting angle, greatly increases the operation difficulty of a doctor, and ensures that the doctor is difficult to avoid important structures such as blood vessels and the like during needle inserting; the plate-shaped electrode is adopted to increase the area parallel to each other between the two electrodes, but the needle insertion wound surface is enlarged, and the needle insertion operation of the plate-shaped electrode is more difficult than that of a needle-shaped electrode.
SUMMERY OF THE UTILITY MODEL
The purpose of the embodiment of the application is to provide a single needle type nanosecond pulse treatment electrode to solve current nanosecond pulse electrode and need two piece at least electrode needles, thereby it influences treatment to be difficult to guarantee to be parallel to each other between the electrode needle, and the operation complicacy needs the needle of inserting many times, the patient wound is great etc. exist not enoughly.
According to an embodiment of the present application, there is provided a single-needle nanosecond pulse treatment electrode including:
the anode electrode needle comprises a needle body and a needle point fixed at the bottom of the needle body;
the cathode sleeve is sleeved outside the needle body, and the outer wall of the cathode sleeve is divided into an insulating covering section and an exposed section;
the first insulating coating is distributed between the needle body and the cathode sleeve;
a second insulating coating covering the insulating cover section;
the holding part is fixed at the upper ends of the cathode sleeve and the anode electrode needle; and
the tail plug is detachably plugged on the holding part and is provided with two electrode connectors which are respectively and electrically connected with the anode electrode needle and the cathode sleeve.
Furthermore, the electric conductivity of the anode electrode needle and the cathode sleeve is more than or equal to 1x10 at room temperature6And (4) making the S/m metal material.
Further, still include:
and the third insulating coating is distributed between the lower end of the cathode sleeve and the upper end of the needle point.
Furthermore, the first insulating coating, the second insulating coating and the third insulating coating all adopt a material with the conductivity of less than or equal to 1x10-13And the second insulating coating and the third insulating coating are made of high polymer materials with low conductivity, good biocompatibility and self-lubricating property.
Further, the holding part is a cylinder with the middle concave towards the inner side.
Furthermore, a metal lead connected with the cathode sleeve is arranged in the holding part, and a metal plug connected with the metal lead is arranged at the tail part of the holding part.
Furthermore, the upper end of the anode electrode needle penetrates through the holding part.
Furthermore, the metal plug is made of stainless steel, and the metal lead is made of copper.
Further, the electrode connector is a metal socket.
Furthermore, the tail plug is made of engineering plastics, and the electrode joint is made of stainless steel.
The technical scheme provided by the embodiment of the application can have the following beneficial effects:
according to the embodiment, compared with the existing nanosecond pulse treatment electrode, the electrode adopts a single-needle nested electrode design, the first insulating coating and the second insulating coating are arranged to ensure that the anode electrode needle and the cathode sleeve are insulated from each other, the needle point and the exposed section are used as treatment areas of the electrode needle, the holding part is favorable for needle holding operation and needle body fixing, and the tail insertion design ensures that the influence of the eccentric center of gravity caused by a long wire during needle inserting operation is avoided. The technical purpose that nanosecond pulse ablation treatment can be carried out by using one electrode is achieved, the problem that electrode needles are difficult to ensure to be parallel to each other in the traditional multi-electrode nanosecond pulse ablation is effectively avoided, and the stability and reliability of the treatment effect are ensured; the first insulating coating replaces a traditional insulating sleeve, the problem that the traditional insulating sleeve is not tightly connected with the electrode needle is solved, and the electrode needle is more compact in structure; the detachable design of tail plug has avoided the long problem that influences the focus skew when operating of electric wire when the needle is gone into.
The nanosecond pulse ablation treatment can be completed by only one electrode needle, and after one-time needle insertion, multipoint position ablation can be performed by changing the needle insertion depth and angle under the guidance of ultrasound, so that compared with the traditional multipoint treatment with multiple electrode needles, the treatment time is shorter, the needle insertion times are fewer, and the burden and the wound of a patient are smaller; the electrode needle has compact integral structure, smaller diameter compared with the traditional treatment electrode with the insulating sleeve, optimized operation hand feeling, reduced resistance of puncture operation, improved convenience and accuracy of needle insertion operation of doctors, and reduced accidental risks of damaging blood vessels during operation.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the present application and together with the description, serve to explain the principles of the application.
Fig. 1 is a schematic side view of a single-needle nanosecond pulse treatment electrode according to an embodiment of the utility model;
FIG. 2 is an enlarged partial view of the needle tip provided in accordance with an embodiment of the present invention;
FIG. 3 is an enlarged view of a grip portion according to an embodiment of the present invention;
FIG. 4 is a schematic top view of a grip portion according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of a tail insertion provided in an embodiment of the present invention;
FIG. 6 is a bottom view of the tail insert provided by an embodiment of the present invention;
FIG. 7 is a two-dimensional schematic diagram of a simulated tissue ablation range provided by an embodiment of the utility model;
fig. 8 is a three-dimensional schematic diagram of a simulated tissue ablation zone according to an embodiment of the present invention.
In the figure: 1. a needle body; 2. a first insulating coating; 3. a cathode sleeve; 4. a second insulating coating; 5. a third insulating coating; 6. an exposed section; 7. a needle tip; 8. a cathode metal plug; 9. a metal wire; 10. a grip portion; 11. an anode metal plug; 12. tail insertion; 13. an anode electrode tab; 14. a cathode electrode tab; 15. a cathode wire; 16. an anode wire; 17. an anode supply connection; 18. and a cathode power supply connector.
Detailed Description
Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present application. Rather, they are merely examples of apparatus and methods consistent with certain aspects of the present application, as detailed in the appended claims.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this application and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
It is to be understood that although the terms first, second, third, etc. may be used herein to describe various information, such information should not be limited to these terms. These terms are only used to distinguish one type of information from another. For example, first information may also be referred to as second information, and similarly, second information may also be referred to as first information, without departing from the scope of the present application. The word "if" as used herein may be interpreted as "at … …" or "when … …" or "in response to a determination", depending on the context.
As shown in fig. 1 and 2, the present invention provides a single-needle nanosecond pulse treatment electrode, which is characterized by comprising: the anode electrode needle comprises an anode electrode needle body 1 and a needle point 7 fixed at the bottom of the needle body 1, a cathode sleeve 3, a first insulating coating 2, a second insulating coating 4, a holding part 10 and a tail insert 12; the cathode sleeve 3 is sleeved outside the needle body 1, and the outer wall of the cathode sleeve 3 is divided into an insulating covering section and an exposed section 6; the first insulating coating 2 is distributed between the needle body 1 and the cathode sleeve 3 to prevent short circuit and breakdown between the electrode needle and the metal sleeve; the second insulating coating 4 covers the insulating cover section; the holding part 10 is fixed at the upper ends of the cathode sleeve 3 and the anode electrode needle; the tail plug 12 is detachably inserted into the holding portion 10, and the tail plug 12 has two electrode connectors which are respectively electrically connected with the anode electrode needle and the cathode casing 3.
According to the technical scheme, the arrangement of the first insulating coating 2 and the second insulating coating 4 ensures that the anode electrode needle and the cathode casing 3 are mutually insulated, the needle point 7 and the exposed section 6 serve as a treatment area of the electrode needle, the holding part 10 is favorable for needle holding operation and fixing the needle body 1, and the design of the tail insert 12 ensures that the influence of the eccentric center of gravity caused by a long wire during needle inserting operation is avoided.
Further, a third insulating coating 5 can be further included, and the third insulating coating 5 is distributed between the lower end of the cathode sleeve 3 and the upper end of the needle tip 7. Specifically, the third insulating coating 5 is shaped like a hollow circular truncated cone, is narrow at the bottom and wide at the top, has the lower end adapted to the diameter of the needle point 7, has the upper end adapted to the outer diameter of the exposed section 6 of the cathode sleeve 3, and has a smooth transition as a whole, thereby being beneficial to increasing the smoothness of the needle insertion operation process, reducing the needle insertion resistance, reducing the operation difficulty and improving the operation precision.
In this embodiment, the first insulating layer 2 has room temperature conductivity of 1 × 10 or less-15S/m polymeric insulating materials, such as polycaprolactone diol type polyurethane elastomers (PCL-PUE); the second insulating coating 4 and the third insulating coating 5 adopt the room temperature conductivity of 1x10 or less-13S/m, good biocompatibility and self-lubricating polymer materials, such as Parylene (Parylene). The first insulating coating 2 is positioned between the needle body 1 and the cathode sleeve 3, and a material with lower conductivity and higher breakdown strength is required to be adopted to ensure that breakdown does not occur between the anode and the cathode and ensure the safety of nanosecond pulse ablation; the second insulating coating 4 and the third insulating coating 5 are directly contacted with the tissues of a patient in the needle inserting operation, and materials with low conductivity, good biocompatibility and self-lubricating property are needed to be adopted, so that the electric leakage of an electrode to the tissues is prevented, the condition of allergy to the electrode needle is avoided, the resistance in the needle inserting process is reduced, and the operation is smoother.
In this embodiment, the anode electrode needle and the cathode casing 3 have conductivities of 1 × 10 or more at room temperature6S/m, such as 304 stainless steel (Fe-18% Cr-8% Ni), 430 stainless steel (Fe-18% Cr), etc.
In this embodiment, the surfaces of the needle point 7 and the exposed section 6 of the anode electrode needle are not covered by the insulating coating, and the two areas form an anode and a cathode during nanosecond pulse ablation treatment, so that an effective treatment area of the single-needle nanosecond pulse treatment electrode is formed, that is, during nanosecond pulse ablation treatment, the needle point 7 and the exposed section 6 need to be completely inserted into a tissue part to be ablated, so as to ensure the coverage and stability of an ablation range.
In this embodiment, as shown in fig. 3, the holding portion 10 is fixed to the upper ends of the cathode cannula 3 and the anode needle, is made of engineering plastics, has good insulation and strong plasticity, and is shaped like a cylinder with an inward curved middle, so as to conform to the curve of a finger, thereby being beneficial to improving the stability and comfort level during holding when performing needle insertion operations such as puncturing and rotating. The holding part 10 is internally provided with a metal lead 9, the lower end of the metal lead 9 is connected with the upper end of the cathode sleeve 3, and the upper end of the metal lead 9 is connected with the cathode metal plug 8, so that current can flow to the cathode metal plug 8 through the cathode sleeve 3 and the metal lead 9. The cathode metal plug 8 is made of stainless steel, and the metal lead 9 is made of copper. Particularly, the upper section of the anode electrode needle body 1 penetrates out of the holding part 10, and the penetrating part is an anode metal plug 11, as shown in fig. 4, the purpose of the anode electrode needle body is to place an anode and a cathode on two plugs in the same plane, so that the structure is more compact, and the anode electrode needle body is convenient to be inserted into a tail plug 12.
In this embodiment, as shown in fig. 5 and 6, the tail plug 12 is detachably mounted on the upper end of the grip portion 10, is shaped like a round button, is made of engineering plastics, and has two electrode connectors and wires connected thereto. Specifically, the electrode connectors are metal sockets made of stainless steel, wherein an anode electrode connector 13 located at the center of the bottom of the tail plug 12 is connected with an anode metal plug 11 in an inserting mode, another cathode electrode connector 14 is connected with a cathode metal plug 8 in an inserting mode, the inner diameters of the two electrode connectors are slightly smaller than the outer diameter of the metal plugs in the inserting mode, and the stability of the tail plug 12 in the inserting mode with the holding portion 10 is improved. The anode wire 16 and the cathode wire 15 are respectively connected with the anode electrode joint 13 and the cathode electrode joint 14, and the material of the wires is a multi-core silica gel high-voltage wire so as to ensure the durability and high-voltage resistance of the wires. Two wires penetrate through the upper part of the tail plug 12, and the tail ends of the two wires are respectively connected with an anode power supply connector 17 and a cathode power supply connector 18, so that the two wires can be conveniently connected with anode and cathode output interfaces of the nanosecond pulse ablation instrument. Because the tail plug 12 integrates the wire and the power supply connector, the mass of the tail plug 12 is larger than that of the main body of the tail plug 12 and the therapeutic electrode, and the integral gravity center can be deviated backwards, the tail plug 12 does not need to be installed in the process of puncture needle insertion operation, the tail plug 12 is inserted into the holding part 10 after the needle insertion operation is completed, the problem that the gravity center of the traditional therapeutic electrode is shifted backwards due to the wire and the power supply connector, so that the needle insertion operation difficulty is increased is solved, and the hand feeling of the needle insertion operation is improved.
Particularly, parameters of an effective treatment area of the nanosecond pulse treatment electrode, namely the diameter of an anode electrode needle, the inner diameter and the outer diameter of a cathode sleeve 3, the length of a needle point 7, the length of a naked section 6 and the length of a third insulating coating 5, jointly determine the size of an ablation range of the treatment area, and by adjusting the values of the parameters, different types of single-needle nanosecond pulse treatment electrodes can be manufactured and used for tumor ablation of different types, sizes, properties and parts. The embodiments do not impose any limitations on the above parameters, and are intended to facilitate understanding of the structure and function of the present invention.
Specifically, the single-needle nanosecond pulse treatment electrode in the embodiment is subjected to COMSOL physical simulation to simulate the ablation condition in liver tissue. The simulation process uses pulse parameters as follows: the output voltage is 25000V, the pulse frequency is 20HZ, the full width at half maximum is 20ns, the falling edge (10-90 percent) is less than or equal to 100ns, and the pulse frequency is 500 times. The parameters of the effective treatment area of the single-needle nanosecond pulse treatment electrode used in the simulation process are as follows: the diameter of the anode electrode needle is 1mm, the outer diameter of the cathode sleeve 3 is 1.8mm, the length of the exposed section 6 is 3mm, the length of the needle tip 7 is 3mm, and the length of the third insulating coating 5 is 3 mm. The simulated ablation range is shown in fig. 7 and 8, the simulation result is good, the voltage output is normal, no breakdown exists between the anode electrode needle and the cathode sleeve 3, and the ablation range is elliptical (two-dimensional) or elliptical (three-dimensional).
According to the embodiment, the anode and the cathode are integrated on the same treatment electrode, and the anode and the cathode are separated by the high-molecular insulating coating, so that the technical purpose of nanosecond pulse ablation treatment can be achieved by only using one treatment electrode, and the problem that the electrodes are difficult to ensure to be parallel to each other in the conventional multi-electrode ablation is solved. In addition, the utility model is also provided with a holding part 10 and a tail plug 12, integrates parts such as an electrode joint, a plug, a lead and the like, can effectively improve the electrical contact quality of the single-needle nanosecond pulse treatment electrode, reduces the operation difficulty and improves the safety.
Specifically, in the present embodiment, the anode electrode needle and the cathode sleeve 3 are respectively used as the anode and the cathode, and are designed in a nested manner, and meanwhile, the first insulating coating 2, the second insulating coating 4, and the third insulating coating 5 are respectively located between the needle body 1 and the cathode sleeve 3, between the insulating covered section of the cathode sleeve 3, between the lower end of the exposed section 6 of the cathode sleeve 3, and between the upper end of the needle tip 7, so that the structure is compact. The material conductivity of the first insulating coating 2 is lower, so that the breakdown between the anode and the cathode is effectively prevented; the materials of the second and third insulating coatings 5 have low conductivity, good biocompatibility and self-lubricity, and can effectively prevent the electrode from leaking electricity to human tissues, prevent material allergy and reduce the resistance of puncture needle insertion. The shape of the holding part 10 is fit with the curve of the fingers, which is beneficial to improving the comfort, accuracy and stability of the operation and plays a role in fixing the electrode needle and the cathode sleeve 3. The tail plug 12 is inserted with the holding part 10, and is detachable, the tail plug 12 is not installed during the needle insertion operation of doctors, so that the problem that the center of gravity of the traditional treatment electrode is shifted backwards due to longer wires is avoided, and the difficulty of the needle insertion operation is effectively reduced. When multi-point ablation treatment is carried out, repeated needle insertion is not needed, the needle insertion depth and angle can be changed, the operation is simple and convenient, the injury to a patient is small, and the clinical application requirement can be effectively met.
The nanosecond pulse ablation treatment can be completed by only one electrode needle, and after one-time needle insertion, multipoint position ablation can be performed by changing the needle insertion depth and angle under the guidance of ultrasound, so that compared with the traditional multipoint treatment with multiple electrode needles, the treatment time is shorter, the needle insertion times are fewer, and the burden and the wound of a patient are smaller; the electrode needle has compact integral structure, smaller diameter compared with the traditional treatment electrode with the insulating sleeve, optimized operation hand feeling, reduced resistance of puncture operation, improved convenience and accuracy of needle insertion operation of doctors, and reduced accidental risks of damaging blood vessels during operation.
The above-mentioned embodiments are intended to illustrate the technical solutions and advantages of the present invention, and it should be noted that the above-mentioned embodiments are only specific implementation examples of the present invention, and do not limit the present invention, and any modifications, additions and equivalents within the scope of the principle of the present invention are included in the protection scope of the present invention.

Claims (10)

1. A single-needle nanosecond pulsed treatment electrode, comprising:
the anode electrode needle comprises a needle body and a needle point fixed at the bottom of the needle body;
the cathode sleeve is sleeved outside the needle body, and the outer wall of the cathode sleeve is divided into an insulating covering section and an exposed section;
the first insulating coating is distributed between the needle body and the cathode sleeve;
a second insulating coating covering the insulating cover section;
the holding part is fixed at the upper ends of the cathode sleeve and the anode electrode needle; and
the tail plug is detachably plugged on the holding part and is provided with two electrode connectors which are respectively and electrically connected with the anode electrode needle and the cathode sleeve.
2. The single-needle nanosecond pulse therapy electrode according to claim 1, wherein the anode electrode needle and the cathode casing have a conductivity of 1x10 or more at room temperature6And (4) making the S/m metal material.
3. The single-needle nanosecond pulse therapy electrode according to claim 1, further comprising:
and the third insulating coating is distributed between the lower end of the cathode sleeve and the upper end of the needle point.
4. The single-needle nanosecond pulse therapy electrode according to claim 1, wherein the first, second and third insulating coatings each have a conductivity of 1x10 or less-13And the second insulating coating and the third insulating coating are made of high polymer materials with low conductivity, good biocompatibility and self-lubricating property.
5. The single-needle nanosecond impulse therapy electrode according to claim 1, wherein the grip is a cylinder with a medial concave portion.
6. The single-needle nanosecond impulse therapy electrode according to claim 1, wherein a metal wire connected to the cathode sleeve is installed in the holding portion, and a metal plug connected to the metal wire is installed at the tail portion of the holding portion.
7. The single-needle nanosecond impulse therapy electrode according to claim 1, wherein an upper end of the anode electrode needle penetrates through the grip portion.
8. The single-needle nanosecond pulse therapy electrode according to claim 6, wherein said metal plug is made of stainless steel and said metal wire is made of copper.
9. The single-needle nanosecond impulse therapy electrode according to claim 1, wherein said electrode contact is a metal socket.
10. The single-needle nanosecond impulse therapy electrode according to claim 1, wherein said tail plug is made of engineering plastic material, and said electrode joint is made of stainless steel material.
CN202122134297.9U 2021-09-06 2021-09-06 Single-needle nanosecond pulse treatment electrode Active CN215839437U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115399869A (en) * 2022-11-02 2022-11-29 杭州维纳安可医疗科技有限责任公司 Ablation needle, processing technology, ablation system and using method thereof
CN115399865A (en) * 2022-11-02 2022-11-29 杭州维纳安可医疗科技有限责任公司 Ablation electrode needle, ablation system and machining process of ablation electrode needle

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115399869A (en) * 2022-11-02 2022-11-29 杭州维纳安可医疗科技有限责任公司 Ablation needle, processing technology, ablation system and using method thereof
CN115399865A (en) * 2022-11-02 2022-11-29 杭州维纳安可医疗科技有限责任公司 Ablation electrode needle, ablation system and machining process of ablation electrode needle

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