CN209237726U - A kind of solution filtering device - Google Patents
A kind of solution filtering device Download PDFInfo
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- CN209237726U CN209237726U CN201821498157.1U CN201821498157U CN209237726U CN 209237726 U CN209237726 U CN 209237726U CN 201821498157 U CN201821498157 U CN 201821498157U CN 209237726 U CN209237726 U CN 209237726U
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- aggregating apparatus
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Abstract
The utility model discloses a kind of solution filtering devices comprising round cuvette, filter membrane and filtrate aggregating apparatus, the filtrate aggregating apparatus are fixed on round cuvette lower part, and the filter membrane is set between round cuvette and filtrate aggregating apparatus；Round cuvette, filter membrane and the filtrate aggregating apparatus collectively constitutes monomer filter device, and the monomer filter device is fixed on the fixed collection device of monomer；The solution filtering device can not only improve working efficiency, reduce the risk that sample is obscured or polluted, and applied widely, have the advantages that high throughput.
Description
Technical field
The utility model relates to filtration arts, and in particular to a kind of solution filtering device.
Background technique
Filter paper acquisition Blood piece is widely applied in clinical examination at this stage, the especially examination of newborn infant diseases, and method is
Blood sample is acquired using special filter paper, then uses instrument to cut the satisfactory blood cake of diameter as experiment sample according to experimental method
This, is put into dissolution in the microwell plate for experiment and elutes blood sample, carry out content detection to target analytes in Blood piece, thus
Aided disease judgement.After the completion of analyte is extracted, if being caused in various degree containing sector-meeting to different detection projects in microwell plate
Influence, some projects are to cause the failure of an experiment, can not obtain testing result；Some projects are to cause cross contamination or test,
Influence the accuracy of testing result；Also it will cause equipment faults for some projects, influence working efficiency.Therefore it is analyzed in blood cake
Object must remove Dried blood spots and impurity in reagent after extracting.
Current main way is that the solution in former experiment microwell plate is transferred to other one piece of sky manually using liquid-transfering gun
In microwell plate, there are corresponding shortcomings for the above way.All liquid relief movements are manually completed by experimenter, workload
Greatly, time-consuming, and the lesser impurity of particles in solution equally exists the possibility for being transferred to new microwell plate, influences subsequent behaviour
Make, while being likely to occur maloperation in operation, obscures sample position, and generate the cross contamination of sample, influence reality
Test the accuracy of result.
It is more and more with filter with many new instruments such as tandem mass spectrometer gradually popularizing in the examination of newborn infant diseases
The dry blood cake of paper is introduced to the market as the project of experiment sample, and the liquid after extracting to blood cake analyte carries out impurity removal and also requires
Higher and higher, existing liquid transfer method is gradually difficult to meet its requirement.There is also many microfiltrations in the market simultaneously
Device, such as: the filter core of filtration protein, the filter core of bacterium, purifying antigen antibody centrifuge tube.But above-mentioned apparatus none be not single
A sample filter device cannot achieve the multiple samples of disposable filtering.
Utility model content
The technical problem to be solved by the present invention is to provide a kind of solution filtering devices, can not only improve work effect
Rate reduces the risk that sample is obscured or polluted, and applied widely, has the advantages that high throughput.
Above-mentioned technical problem to be solved in the utility model is achieved by the following technical programs:
A kind of solution filtering device comprising round cuvette, filter membrane and filtrate aggregating apparatus, the filtrate aggregating apparatus
It is fixed on round cuvette lower part, the filter membrane is set between round cuvette and filtrate aggregating apparatus；The round cuvette, filter
Film and filtrate aggregating apparatus collectively constitute monomer filter device, and the monomer filter device is fixed on the fixed collection device of monomer.
Preferably, the round cuvette is the frustum cone structure put upside down, and internal is cavity, and open-minded up and down, the filter membrane is
Circular configuration, size match with round cuvette lower end area, and the filtrate aggregating apparatus is the frustum cone structure put upside down,
It is cavity that it is internal, and upper end is open-minded；Filtrate aggregating apparatus upper inner diameter is matched with round cuvette lower outer diameter, and filtrate collects dress
Set and be fixed on round cuvette lower part, filter membrane by filter aggregating apparatus be fixed on round cuvette lower end, i.e., filtering aggregating apparatus with
Among round cuvette.
It is further preferred that the lower end of the filtering aggregating apparatus has the collector groove of back taper, collector groove lower end is
Through-hole.
Preferably, the fixed collection device of the monomer is centrifuge tube, and the centrifuge tube includes: centrifuge tube lid, centrifuge tube
Main body and connection strap, the centrifuge tube main body generally pyramidal structure, the upper end has the opening to match with centrifuge tube lid, internal
For cavity structure, centrifuge tube main body is divided into two sections；Upper section cross section is greater than lower section cross section, and upper intersegmental part places monomer mistake
Device is filtered, lower section blocks the lower end of monomer filter device just；There is protrusion platform, the protrusion among centrifuge tube lid lower end
The upper-end inner diameter of platform outer diameter and monomer filter device circle cuvette matches, and monomer filter device is fixed on centrifugation lid lower end；It is described
Connection strap both ends are respectively fixedly connected in centrifuge tube lid and centrifuge tube main body.
Preferably, adjacent monomer filter device is fixedly connected on one by connection structure by the monomer filter device
It rises, forms filter device group, the filter device group is made of more than one monomer filter device, and filter device group is fixed on
Filter device group fixes collection device.
It is further preferred that the connection structure includes: adhesion article and adhesion piece；The adhesion article both ends are separately connected
In the outer upper end of adjacent two round cuvettes；Adhesion piece both ends are connected to two neighboring filtering aggregating apparatus
Outer upper end, more than one monomer filter device are connected in a row by adhesion article and adhesion piece, collectively constitute filter device group.
It is further preferred that the viscous latticing is preferably two, their flush with each other, the adhesion article and circle are small
Cup connecting place is provided with cutting line, and the adhesion piece and filtrate aggregating apparatus connecting place are provided with cutting line.
It is further preferred that the round cuvette of the outermost two monomer filter devices of the filter device group is in the outer part
One end top have protrusion rectangle side handle.
It is further preferred that the fixed collection device of the filter device group is multi-well microplate, the multi-well microplate
On be evenly distributed with placed hole, each monomer filter device of filter device group corresponds the placed hole on multi-well microplate,
Filter device group is mounted on multi-well microplate.
It is further preferred that the multi-well microplate is preferably 96 hole microwell plates.
The utility model has the advantages that after using structure described in the utility model, since solution filtering device is using round cuvette, filter membrane
The filter device collectively constituted with filtrate aggregating apparatus, and monomer filter device or filter device group, there is corresponding centrifuge tube
Or the fixed collection device of multi-well microplate, fixed collection device have the one-to-one hole for being used to collect filtrate, realize filtering, receive
Collection, the repertoire of transfer can substantially reduce the labor intensity of operator relative to existing manual branch mode, reduce
Operating time reduces the cross contamination of sample because sample position is obscured caused by artificial maloperation, and can filter out compared with
Small impurity improves the accuracy and working efficiency of experimental result；Simultaneously because filter membrane is fixed by filtrate aggregating apparatus
Under round cuvette, and filtrate aggregating apparatus and round cuvette are detachable structure, keep the replacement of filter membrane simple and convenient, Er Qieke
To pass through the mistake for filtering such as serum, bacterium, protein, nucleic acid macromolecular substances or even pearl with the filter membrane of different pore size
Filter, usage range are very wide；And filter device can be placed on multi-well microplate and be filtered, and disposably may filter that multiple samples
This, has the advantages that high throughput；Adhesion article and round cuvette connecting place are provided with cutting line, adhesion piece and filtrate aggregating apparatus phase
Be provided with cutting line at even, adhesion article and adhesion piece made to be easy to tear open and break, can select according to demand the filter device of suitable number into
Row filtering, filtrate aggregating apparatus lower end have the collector groove of back taper, make what filtrate more concentrated to pool together, facilitate receipts
Collection；And the monomer aggregating apparatus that filtering collects the outermost two sides of group is provided with side handle, the installation facilitated in experimentation picks and places, and turns
It moves.
Detailed description of the invention
Fig. 1 is the top view that filter device group is placed on more microwell plates.
Fig. 2 is the exploded view of filter device group.
Fig. 3 is the top view of filter device group.
Fig. 4 is monomer filter apparatus configuration figure.
Fig. 5 is the exploded view of monomer filter device.
The structure chart of Fig. 6 centrifuge tube.
Fig. 7 is the installation cooperation figure of monomer filter device and centrifuge tube.
Specific embodiment
The present invention is described in further detail in the following with reference to the drawings and specific embodiments, but embodiment to the present invention not
It limits in any form.
Embodiment 1
A kind of solution filtering device as shown in figs. 1-7 comprising round cuvette (4), filter membrane (5) and filtrate aggregating apparatus
(6), the round cuvette (4), filter membrane (5) and filtrate aggregating apparatus collectively constitute monomer filter device (3), and the circle is small
Cup (4) is the frustum cone structure put upside down, and internal is cavity, and open-minded up and down, the filter membrane (5) is circular configuration, size
Matching with round cuvette lower end area, the filtrate aggregating apparatus (6) is the frustum cone structure put upside down, and internal is cavity, on
It holds open-minded；Filtrate aggregating apparatus (6) upper inner diameter is matched with round cuvette (4) lower outer diameter, and filtrate aggregating apparatus (6) is fixed
In round cuvette (4) lower part, filter membrane (5) is fixed on round cuvette (4) lower end by filtering aggregating apparatus (6), i.e. filtering collects
Device (6) and round cuvette (4) are intermediate, and the lower end of the filtering aggregating apparatus (6) has the collector groove (61) of back taper, converge
Integrate slot (61) lower end as through-hole.The monomer filter device (3) is fixed on centrifuge tube (7), the centrifuge tube (7) include: from
Heart pipe lid (71), centrifuge tube main body (73) and connection strap (72), the centrifuge tube main body (73) generally pyramidal structure, the upper end
With the opening to match with centrifuge tube lid (71), inside is cavity structure, and centrifuge tube main body (73) is divided into two sections；Upper section is horizontal
Sectional area is greater than lower section cross-sectional area, and upper intersegmental part places monomer filter device (3), and lower section blocks monomer filter device just
(3) lower end, for collecting filtrate；There are protrusion platform (711) among centrifuge tube lid (71) lower end, the protrusion platform outer diameter
Match with the upper-end inner diameter of the round cuvette (4) of monomer filter device (3), monomer filter device (3) is fixed under centrifugation lid (71)
End；Connection strap (72) both ends are respectively fixedly connected in centrifuge tube lid (71) and centrifuge tube main body (73).The monomer mistake
Adjacent monomer filter device (3) is fixedly connected on together by filter device (3) by connection structure, is formed filter device group (2),
Filter device group (2) is made of more than one monomer filter device (3), the connection structure include: adhesion article (41) and
Adhesion piece (62)；The adhesion article (41) has two, their flush with each other, and adhesion article (41) both ends are connected to adjacent two
The outer upper end of a circle cuvette；Adhesion piece (62) both ends are connected to the outer of two neighboring filtering aggregating apparatus (6)
Side upper end, more than one monomer filter device (3) is even in a row by adhesion article (41) and adhesion piece (62), collectively constitutes
Filter device group；The adhesion article (41) and round cuvette (4) connecting place are provided with cutting line, the adhesion piece (62) and filter
Liquid aggregating apparatus (6) connecting place is provided with cutting line, make adhesion article (41) and adhesion piece (62) be easy to break it is disconnected.The filtering dress
Setting one end top of the round cuvette (4) of the outermost two monomer filter devices (3) of group (2) in the outer part has the rectangular of protrusion
Shape side handle (42).The filter device group (2) is fixed on multi-well microplate (1), and the multi-well microplate (1) is that 96 holes are micro-
Orifice plate is rectangular parallelepiped structure, and uniform array has 8 × 12 placed holes on multi-well microplate (1), and multi-well microplate (1) is placed
12 groups of filter device groups (2), every group of filter device group (2) have 8 monomer filter devices (3), each list of filter device group (2)
Body filter device (3) corresponds the placed hole on multi-well microplate (1)；Multi-well microplate (1) upper end side blank space is every
The corresponding position of a line indicates (11) with the sequence of A-H.
In use, selecting suitable filter membrane (5) according to material type to be filtered, according to the quantity of filtered fluid, it is suitable to select
Filter device quantity, liquid to be filtered is transferred on filter device, filter device is fixed on corresponding centrifuge tube (7) or more
Hole microwell plate (1) fixes collection device, is placed in centrifuge, selects suitable parameter of noncentricity to carry out centrifugal filtration, takes after centrifugation
Out, fixed collection device can obtain the corresponding filtered filtrate of filter device, gained filtrate can be carried out subsequent experiment and grasped
Make.
The preferable specific embodiment of the above, only the utility model, but the protection scope of the utility model is not
It is confined to this, anyone skilled in the art is within the technical scope disclosed by the utility model, practical according to this
Novel technical solution and utility model design are subject to equivalent substitution or change, should all cover in the protection scope of the utility model
Within.
Claims (10)
1. a kind of solution filtering device comprising round cuvette (4), filter membrane (5) and filtrate aggregating apparatus (6), which is characterized in that
The filtrate aggregating apparatus (6) is fixed on round cuvette (4) lower part, and the filter membrane (5) is set to round cuvette (4) and filtrate
Between aggregating apparatus (6)；Round cuvette (4), filter membrane (5) and the filtrate aggregating apparatus collectively constitutes monomer filter device
(3), the monomer filter device (3) is fixed on the fixed collection device of monomer.
2. solution filtering device according to claim 1, which is characterized in that the circle cuvette (4) is the rotary table put upside down
Structure, internal is cavity, open-minded up and down, and the filter membrane (5) is circular configuration, size and round cuvette lower end area
Match, the filtrate aggregating apparatus (6) is the frustum cone structure put upside down, and internal is cavity, and upper end is open-minded；Filtrate aggregating apparatus
(6) upper inner diameter is matched with round cuvette (4) lower outer diameter, and filtrate aggregating apparatus (6) is fixed on round cuvette (4) lower part,
Filter membrane (5) is fixed on round cuvette (4) lower end, i.e. filtrate aggregating apparatus (6) and round cuvette by filtrate aggregating apparatus (6)
(4) intermediate.
3. solution filtering device according to claim 2, which is characterized in that the lower end of the filtrate aggregating apparatus (6)
Collector groove (61) with back taper, collector groove (61) lower end are through-hole.
4. solution filtering device according to claim 1, which is characterized in that the fixed collection device of the monomer is centrifugation
It manages (7), the centrifuge tube (7) includes: centrifuge tube lid (71), centrifuge tube main body (73) and connection strap (72), the centrifuge tube master
Body (73) generally pyramidal structure, the upper end have the opening to match with centrifuge tube lid (71), and inside is cavity structure, centrifuge tube
Main body (73) is divided into two sections；Upper section cross section is greater than lower section cross section, and upper intersegmental part places monomer filter device (3), under
Section blocks the lower end of monomer filter device (3) just；There are protrusion platform (711) among centrifuge tube lid (71) lower end, it is described
The upper-end inner diameter of the round cuvette (4) in protrusion platform outer diameter and monomer filter device (3) matches, monomer filter device (3) be fixed on from
Heart pipe lid (71) lower end；Connection strap (72) both ends are respectively fixedly connected in centrifuge tube lid (71) and centrifuge tube main body (73).
5. solution filtering device according to claim 1, which is characterized in that the monomer filter device (3) passes through company
Adjacent monomer filter device (3) is fixedly connected on together by binding structure, is formed filter device group (2), the filter device group
(2) it is made of more than one monomer filter device (3), filter device group (2) is fixed on the fixed collection device of filter device group.
6. solution filtering device according to claim 5, which is characterized in that the connection structure includes: adhesion article
(41) and adhesion piece (62)；Adhesion article (41) both ends are connected to the outer upper end of the round cuvette (4) of adjacent two；It is described
Adhesion piece (62) both ends are connected to the outer upper end of two neighboring filtrate aggregating apparatus (6), more than one monomer filtering
Device (3) is even in a row by adhesion article (41) and adhesion piece (62), collectively constitutes filter device group.
7. solution filtering device according to claim 6, which is characterized in that the adhesion article (41) is two, they
Flush with each other, the adhesion article (41) and round cuvette (4) connecting place are provided with cutting line, the adhesion piece (62) and filter
Liquid aggregating apparatus (6) connecting place is provided with cutting line.
8. solution filtering device according to claim 5, which is characterized in that the filter device group (2) is outermost
One end top of the round cuvette (4) of two monomer filter devices (3) in the outer part has the rectangle side handle (42) of protrusion.
9. solution filtering device according to claim 5, which is characterized in that the fixed collection device of the filter device group
For multi-well microplate (1), placed hole, each monomer mistake of filter device group (2) are evenly distributed on the multi-well microplate (1)
The placed hole on device (3) one-to-one correspondence multi-well microplate (1) is filtered, filter device group (2) is mounted on multi-well microplate (1)
On.
10. solution filtering device according to claim 9, which is characterized in that the multi-well microplate (1) is that 96 holes are micro-
Orifice plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821498157.1U CN209237726U (en) | 2018-09-13 | 2018-09-13 | A kind of solution filtering device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821498157.1U CN209237726U (en) | 2018-09-13 | 2018-09-13 | A kind of solution filtering device |
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| CN209237726U true CN209237726U (en) | 2019-08-13 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109046026A (en) * | 2018-09-13 | 2018-12-21 | 广州俊通生物科技有限公司 | A kind of solution filtering device |
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- 2018-09-13 CN CN201821498157.1U patent/CN209237726U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109046026A (en) * | 2018-09-13 | 2018-12-21 | 广州俊通生物科技有限公司 | A kind of solution filtering device |
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