CN209065899U - Bioreactor online disinfection system in situ - Google Patents
Bioreactor online disinfection system in situ Download PDFInfo
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- CN209065899U CN209065899U CN201821574677.6U CN201821574677U CN209065899U CN 209065899 U CN209065899 U CN 209065899U CN 201821574677 U CN201821574677 U CN 201821574677U CN 209065899 U CN209065899 U CN 209065899U
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Abstract
The utility model discloses a kind of bioreactor online disinfection systems in situ, including reactor tank body, respectively be independently connected the inlet pipeline of the reactor tank body, discharge pipe line, air inlet/vapor pipeline, exhaust pipe road, feed supplement pipeline, tank bottom blowing pipeline and sampling line, air inlet pipeline is narrated in connection, exhaust pipe road, feeding pipe, tank bottom blowing pipeline, the steam pipework of sampling line, the temperature sensor being set on each pipeline and corresponding control valve, temperature sensor is connected to a control system, detection control and record are carried out by temperature to the condensed water elimination point on each pipeline and tank pressure, when ensuring just to start when the temperature of each point reaches sterilising temp sterilometer, guarantee that each point sterilization process is abundant, data are provided simultaneously for analysis microbiological contamination reason to support.
Description
Technical field
In particular to a kind of bioreactor of the utility model online disinfection system in situ, belongs to biotechnological device technology
Field.
Background technique
In bioreactor online sterilization process in situ, the temperature of tank body is usually only detected, tank temperature reaches setting sterilizing temperature
Spend and maintain to think after a certain period of time that sterilization process is completed, but in real process, due to deep bed filter, both surface filtration device,
Exhaust gas filter, feed supplement valve group, bottom valve, sampling valve sterilizing are not thorough the event of microbiological contamination are caused to happen occasionally.When each branch steams
Filtering can not be completely secured even if pot temperature reaches setting sterilising temp in vapour amount deficiency, line clogging, valve damage
Device, feed supplement valve group, bottom valve, sampling valve sterilizing are thorough.
In addition, Nanjing is adopted than the cold junction temperature control system (patent CN203360444U) of auspicious Biotechnology Co., Ltd
It is connect with pneumatic combined drain valve with gas source, the signal input part of computer control system is connected with condensation temperature element, meter
The signal output end of calculation machine is connect with gas source.When cold junction temperature is greater than set temperature, computer control system controls respective tube
The pneumatic actuator in road is closed, and corresponding pneumatic type drain valve is closed, and condensed water is discharged through the throttle orifice of drain valve；Work as cold end
When temperature is less than set temperature, the pneumatic actuator that computer control system controls corresponding pipeline is opened, corresponding pneumatic type
Drain valve is opened, and condensed water is not discharged.The opening and closing that pneumatic combined drain valve is controlled using cold junction temperature signal can reach resistance vapour
The purpose of draining.Once cannot achieve however, abnormal failure occur in cold junction temperature probe or gas source and be effectively discharged out condensed water.
Such case can effectively avoid using hot power, thermostatic or mechanical drain valve.
Utility model content
The main purpose of the utility model is to provide a kind of bioreactor online disinfection systems in situ, by biology
Heater, deep bed filter, both surface filtration device, exhaust gas filter, feed supplement valve between reactor, inlet pipeline and discharge pipe line
Group, bottom valve, sampling valve condensed water elimination point temperature and tank pressure carry out detection control and record, guarantee the temperature of the above each point
When degree reaches sterilising temp, when just starting sterilometer, guarantee that each point sterilization process is abundant, while providing number for analysis microbiological contamination reason
According to support.
To achieve the above object, the utility model provides the following technical solutions:
The utility model embodiment provides a kind of bioreactor online disinfection system in situ, including reacting tank body, each
From inlet pipeline, the discharge pipe line, air inlet/vapor pipeline, exhaust pipe road, feed supplement pipe of the reactor tank body that is independently connected
Road, tank bottom blowing pipeline and sampling line connect the air inlet pipeline, exhaust pipe road, feed supplement pipeline, tank bottom vomit pipe
Road, sampling line steam pipework, be respectively equipped with control valve on each pipeline, the air inlet pipeline includes deep layer air inlet
Pipeline and surface layer air inlet pipeline, the disinfection system are provided with temperature sensor, the water inlet pipe in the reactor tank body
Electric heater and water circulating pump are connected to and are provided between road and discharge pipe line, the electric heater is equipped with temperature sensor,
The exhaust pipe road is provided with exhaust gas filter, and temperature biography is provided on the condensate drainage pipeline of the exhaust gas filter
Sensor and control valve, are provided with deep ventilation filter on the deep layer air inlet pipeline, the deep ventilation filter it is cold
It is provided with temperature sensor and control valve on solidifying discharge pipe, is provided with surface layer vent filter on the surface layer air inlet pipeline
Device is provided with temperature sensor and control valve, the tank bottom blowing on the condensate drainage pipeline of the surface layer breather filter
It is provided with temperature sensor and control valve on the condensate drainage pipeline of pipeline, divides on the condensate drainage pipeline of the feed supplement pipeline
It is not provided with temperature sensor and tank bottom control valve, is provided with temperature sensor on the condensate drainage pipeline of the sampling line
With sampling control valve, the control valve is connected to corresponding temperature sensor, and the temperature sensor is connected to one
Controller.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the steam pipework and air inlet pipeline, tail gas
Gas exhaust piping connection, and each junction is provided with pneumatic diaphragm valve, the steam pipework and feed supplement piping connection, it is connecting
Both ends be provided with automatic ball valve and manual diaphragm valve, the steam pipework is connect with tank bottom blowing pipeline and sampling line, if
It is equipped with automatic ball valve, the water inlet, discharge pipe line, admission passage and bioreactor connect, and are provided with pneumatic angle pedestal valve, institute
It states feed supplement pipeline, tank bottom blowing pipeline and sampling line to connect with bioreactor, and is provided with manual diaphragm valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the tail gas mistake of the tail gas discharging pipe road
Filter connects external electric device.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the air inlet pipeline, feed supplement pipeline and tail gas
Gas exhaust piping is connected to bioreactor upper part, and the tank bottom blowing pipeline setting is described to take in bioreactor bottom
Sample piping connection is in the end portion of bioreactor.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the inside bioreactor, which is provided with, to be stirred
Mix device.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the air intake filter and discharge filter
It is made of filter housing and filter core.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the condensate drainage pipeline bottom of each pipeline
End is provided with drain valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the feed supplement line entry is separately connected compacted
Dynamic pump.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the sampling line and bioreactor connect
It meets place and is equipped with sampling valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the tank bottom blowing pipeline and biological respinse
Device junction is provided with bottom valve.
Compared with prior art, the bioreactor online disinfection system in situ that technical solutions of the utility model provide,
Advantage is: by the heater between bioreactor, inlet pipeline and discharge pipe line, deep bed filter, both surface filtration
Device, exhaust gas filter, feed supplement valve group, bottom valve, sampling valve condensed water elimination point temperature and tank pressure carry out detection control and
Record when guaranteeing that the temperature of the above each point reaches sterilising temp, when just starting sterilometer, guarantees that each point sterilization process is abundant, section
About sterilize cost, due to joined computer control system, realizes automation sterilizing management, while can be analysis microbiological contamination reason
Data are provided to support.
Detailed description of the invention
In order to illustrate the technical solutions in the embodiments of the present application or in the prior art more clearly, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
The some embodiments recorded in application, for those of ordinary skill in the art, without creative efforts,
It is also possible to obtain other drawings based on these drawings；
Fig. 1 show a kind of bioreactor online disinfection system structural representation in situ in the utility model specific embodiment
Figure.
Specific embodiment
In view of deficiency in the prior art, inventor is studied for a long period of time and is largely practiced, and is able to propose that this is practical new
The technical solution of type.The technical solution, its implementation process and principle etc. will be further explained as follows.
The utility model embodiment provides a kind of bioreactor online disinfection system in situ, including reacting tank body, each
From inlet pipeline, the discharge pipe line, air inlet/vapor pipeline, exhaust pipe road, feed supplement pipe of the reactor tank body that is independently connected
Road, tank bottom blowing pipeline and sampling line connect the air inlet pipeline, exhaust pipe road, feed supplement pipeline, tank bottom vomit pipe
Road, sampling line steam pipework, be respectively equipped with control valve on each pipeline, the air inlet pipeline includes deep layer air inlet
Pipeline and surface layer air inlet pipeline, the disinfection system are provided with temperature sensor, the water inlet pipe in the reactor tank body
Electric heater and water circulating pump are connected to and are provided between road and discharge pipe line, the electric heater is equipped with temperature sensor,
The exhaust pipe road is provided with exhaust gas filter, and temperature biography is provided on the condensate drainage pipeline of the exhaust gas filter
Sensor and control valve, are provided with deep ventilation filter on the deep layer air inlet pipeline, the deep ventilation filter it is cold
It is provided with temperature sensor and control valve on solidifying discharge pipe, is provided with surface layer vent filter on the surface layer air inlet pipeline
Device is provided with temperature sensor and control valve, the tank bottom blowing on the condensate drainage pipeline of the surface layer breather filter
It is provided with temperature sensor and control valve on the condensate drainage pipeline of pipeline, divides on the condensate drainage pipeline of the feed supplement pipeline
It is not provided with temperature sensor and tank bottom control valve, is provided with temperature sensor on the condensate drainage pipeline of the sampling line
With sampling control valve, the control valve is connected to corresponding temperature sensor, and the temperature sensor is connected to one
Controller.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the steam pipework and air inlet pipeline, tail gas
Gas exhaust piping connection, and each junction is provided with diaphragm valve, the steam pipework and feed supplement piping connection, the two of connection
End is provided with automatic ball valve and manual diaphragm valve, and the steam pipework connect with tank bottom blowing pipeline and sampling line, is provided with
Automatic ball valve, the water inlet, discharge pipe line, admission passage and bioreactor connect, and are provided with pneumatic angle pedestal valve, the benefit
Expects pipe road, tank bottom blowing pipeline and sampling line are connect with bioreactor, and are provided with manual diaphragm valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the tail gas mistake of the tail gas discharging pipe road
Filter connects external electric device.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the air inlet pipeline, feed supplement pipeline and tail gas
Gas exhaust piping is connected to bioreactor upper part, and the tank bottom blowing pipeline setting is described to take in bioreactor bottom
Sample piping connection is in the end portion of bioreactor.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the inside bioreactor, which is provided with, to be stirred
Mix device.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the air intake filter and discharge filter
It is made of filter housing and filter core.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the condensate drainage pipeline bottom of each pipeline
End is provided with drain valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the feed supplement line entry is separately connected compacted
Dynamic pump.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the sampling line and bioreactor connect
It meets place and is equipped with sampling valve.
Preferably, in above-mentioned bioreactor online disinfection system in situ, the tank bottom blowing pipeline and biological respinse
Device junction is provided with bottom valve.
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Detailed description.
Referring to Fig. 1, Fig. 1 is a kind of bioreactor provided by the embodiment of the utility model online disinfection system knot in situ
Structure schematic diagram, the system include reacting tank body, the inlet pipeline for the reactor tank body that is respectively independently connected, discharge pipe line, into
Gas vapor pipeline, exhaust pipe road, feed supplement pipeline, tank bottom blowing pipeline and sampling line, connect above-mentioned air inlet pipeline, tail gas
Gas exhaust piping, feed supplement pipeline, tank bottom blowing pipeline, sampling line steam pipework, be set on each pipeline condenser pipe
Temperature sensor and control valve, temperature sensor connect a control system.
After putting into appropriate PBS solution in biological reactor, check whether equipment can be sterilized automatically, inspection finishes i.e.
Automatic sterilizing program (ensuring that all valves are closed, jacket water (J.W.) empties, condensed water emptying in steam pipework) can be entered:
1, warm-up phase
Open steam condensate outlet valve 101,102,103, outlet valve 110；Check the filter for closing exhaust emissions pipeline
Steam inlet valve 104, the filter outlet valve 105 of exhaust emissions pipeline, the filter outlet valve 111 of surface layer air inlet pipeline, depth
The filter outlet valve 108 of layer air inlet pipeline opens the filter inlet valve 107 of exhaust emissions pipeline, exhaust emissions pipeline
Filter steam condensate outlet valve 106；
Check the chilled water inlet valve 201 for closing jacket heat-preservation, that opens jacket heat-preservation empties drain valve 202, after 3min
It is automatically closed, opens the condensed water drain valve 206 and condensed water of jacket heat-preservation；Check the Overflow drainage valve for closing jacket heat-preservation
205, the exhaust valve 204 of jacket heat-preservation automatically turns on stirring, 50rpm；The industrial steam inlet valve of jacket heat-preservation is opened simultaneously
203, steam enters collet；
When tank temperature rises to 95 DEG C, checks and close the filter inlet valve on the air inlet pipeline of surface layer, on deep layer air inlet pipeline
Filter inlet valve, the air bypass valve on deep layer air inlet pipeline, the filter steam first opened on the air inlet pipeline of surface layer is cold
Filter steam condensate outlet valve 109 on solidifying outlet valve 112, deep layer air inlet pipeline, the mistake being then turned on the air inlet pipeline of surface layer
Filter steam inlet valve 113 on filter steam inlet valve 21, deep layer air inlet pipeline；It is opened on the air inlet pipeline of surface layer after 30s
Filter outlet valve 111 and deep layer air inlet pipeline on filter outlet valve 108, steam enters in tank.
2, sterilization phase
Successively open sampling valve steam condensate outlet valve 114, sampling valve steam inlet valve 115.Bottom valve is successively opened to steam
Vapour condensate outlet valve 116, bottom valve steam inlet valve 23.The filter inlet valve 107 for closing tail gas discharging pipe road, makes tank pressure
It increases, temperature also can be increased accordingly；
When tank temperature rises to 121 DEG C of (under saturated vapor, tank pressure is 0.12MPa) left and right, when culture-liquid temp 1, tail in tank
The steam condensate outlet temperature 4 in steam condensate outlet temperature 3, deep layer air inlet pipeline on air pipe, on the air inlet pipeline of surface layer
Steam condensate outlet temperature 5, the steam condensate outlet temperature 6 on bottom valve pipeline, the steam on 1 pipeline of feed supplement valve is condensed out
Mouth temperature 7, the steam condensate outlet temperature 9 on 3 pipeline of feed supplement valve, takes the steam condensate outlet temperature 8 on 2 pipeline of feed supplement valve
Steam condensate outlet temperature 10 on sample valve pipeline starts to clock when reaching 121 DEG C, maintains 121 DEG C/1800s；If there is small
In 121 DEG C, reclocking is needed；After maintaining 1800s, filter inlet valve 107, the exhaust emissions of tail gas discharging pipe road are closed
The filter outlet valve 111 on filter outlet valve 105, surface layer air inlet pipeline on pipeline, the filtering on deep layer air inlet pipeline
Device outlet valve 108；
In sterilization process, adjust in the following manner:
When pressure P1 is higher than 0.12MPa, filter inlet valve 107, the tail of tail gas discharging pipe road are opened by gap
Filter outlet valve 105 on gas discharge pipe controls pressure P1；
3, cooling stage
Outlet valve 110 is closed, steam condensate outlet valve 101,102,103 is turned off；Successively close the condensation of sampling valve steam
Outlet valve 114, sampling valve steam inlet valve 115.Successively close bottom valve steam condensate outlet valve 116, bottom valve steam inlet
Valve 23.Close the filter outlet valve 111 on the air inlet pipeline of surface layer, after the filter outlet valve 108 on deep layer air inlet pipeline, then
Close the industrial steam inlet valve 203 of jacket heat-preservation, the condensed water drain valve 206 of jacket heat-preservation, the mistake on the air inlet pipeline of surface layer
Filter steam inlet valve 113 on filter steam inlet valve 21, deep layer air inlet pipeline；
Open air inlet valve, the filter inlet valve on the air inlet pipeline of surface layer, deep layer air inlet on the air inlet pipeline of surface layer
The filter inlet valve on air inlet valve, deep layer air inlet pipeline, the air bypass valve on deep layer air inlet pipeline on pipeline,
Filter steam after 10s on the filter steam condensate outlet valve 106, surface layer air inlet pipeline of closing tail gas discharging pipe road is cold
Filter steam condensate outlet valve 109 on solidifying outlet valve 112, deep layer air inlet pipeline, the mistake being then turned on the air inlet pipeline of surface layer
Filter outlet valve 108 on filter outlets valve 111, deep layer air inlet pipeline；Filtrated air enters in tank, is opened and closed tail by gap
The filter outlet valve 105 of filter inlet valve 107, tail gas discharging pipe road on gas discharge pipe is pressed in control tank
0.02~0.05MPa；
After heater entrance removes the Overflow drainage valve 205 of valve 207, jacket heat-preservation, it is then turned on chilled water inlet valve
201, so that chilled water is entered collet rapid cooling；Open filter inlet valve 107, the exhaust emissions pipeline of tail gas discharging pipe road
On filter outlet valve 105, the filter steam condensate outlet valve 112 on the air inlet pipeline of surface layer, on the air inlet pipeline of surface layer
The filter steam on filter inlet valve, deep layer air inlet pipeline on filter outlet valve 111, surface layer air inlet pipeline is condensed out
Mouth valve 109, the filter inlet valve on deep layer air inlet pipeline, the filter outlet valve 108 on deep layer air inlet pipeline；After 1800s,
Filter steam condensate outlet valve 112, the filter steam on deep layer air inlet pipeline closed on the air inlet pipeline of surface layer are condensed out
Mouth valve 109, the filter outlet valve 108 on deep layer air inlet pipeline, the filter inlet valve on deep layer air inlet pipeline.
When tank temperature reaches 50 DEG C, the filtering steam condensate outlet valve 106 of tail gas discharging pipe road is closed, opens tail gas row
The filter inlet valve 107 of filter outlet valve 105 on pipeline, tail gas discharging pipe road is put, tank pressure is controlled automatically by counterbalance valve
System；
When tank temperature reaches 37 DEG C, automatic sterilization process all terminates, and tank temperature should be switched to temperature automatically controlled mode: electric heating
Device 81 and water pump 82 are opened, temp autocontrolled, and open the filter outlet valve 111 on the air inlet pipeline of surface layer and surface layer air inlet pipe
The filter inlet valve of road closes the air inlet valve on deep layer air inlet pipeline.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and
And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms
Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new
The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in
All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting
Related claim.
It should be appreciated that above-described embodiment is only to illustrate the technical ideas and features of the present invention, it is ripe its object is to allow
The personage for knowing technique can understand the content of the utility model and implement accordingly, can not limit the utility model with this
Protection scope.All equivalent change or modifications according to made by the spirit of the present invention essence, should all cover in the utility model
Within protection scope.
Claims (10)
1. a kind of bioreactor online disinfection system in situ, comprising: reactor tank body, be respectively independently connected the reactor tank
Inlet pipeline, discharge pipe line, air inlet/vapor pipeline, exhaust pipe road, feed supplement pipeline, tank bottom blowing pipeline and the probe tube of body
Road connects the steam pipework of the air inlet pipeline, exhaust pipe road, feed supplement pipeline, tank bottom blowing pipeline, sampling line, institute
State and be respectively equipped with control valve on each pipeline, it is characterised in that: the air inlet pipeline include deep layer air inlet pipeline and surface layer into
Air pipe, the disinfection system are provided with temperature sensor, the inlet pipeline and discharge pipe line in the reactor tank body
Between be connected to and be provided with electric heater and water circulating pump, the electric heater is equipped with temperature sensor, the tail gas exhaust
It is provided with exhaust gas filter on pipeline, is provided with temperature sensor and control valve on the condensate drainage pipeline of the exhaust gas filter
Door, is provided with deep ventilation filter on the deep layer air inlet pipeline, on the condensate drainage pipeline of the deep ventilation filter
It is provided with temperature sensor and control valve, surface layer breather filter is provided on the surface layer air inlet pipeline, the surface layer is logical
Temperature sensor and control valve, the condensate drainage of the tank bottom blowing pipeline are provided on the condensate drainage pipeline of air filter
It is provided with temperature sensor and control valve on pipeline, temperature biography is respectively arranged on the condensate drainage pipeline of the feed supplement pipeline
Sensor and tank bottom control valve are provided with temperature sensor and sampling control valve on the condensate drainage pipeline of the sampling line
Door, the control valve are connected to corresponding temperature sensor, and the temperature sensor is connected to a controller.
2. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the steam pipe
Road is connect with air inlet pipeline, exhaust pipe road, and each junction is provided with pneumatic diaphragm valve, the steam pipework and benefit
Expect piping connection, the both ends of connection are provided with ball valve, diaphragm valve, the steam pipework and tank bottom blowing pipeline and sampling line
Connection is provided with ball valve, and the water inlet, discharge pipe line, admission passage and bioreactor connect, and are provided with angle pedestal valve, institute
It states feed supplement pipeline, tank bottom blowing pipeline and sampling line to connect with bioreactor, and is provided with diaphragm valve.
3. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the tail gas row
Put the exhaust gas filter connection external electric device on pipeline.
4. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the air inlet pipe
Road, feed supplement pipeline and exhaust pipe road are connected to bioreactor upper part, and the tank bottom blowing pipeline is arranged in biology
Reactor bottom, the sampling line are connected to the end portion of bioreactor.
5. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the biology is anti-
Device is answered to be internally provided with blender.
6. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the air inlet
Filter and discharge filter are made of filter housing and filter core.
7. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: each pipeline
Condensate drainage pipeline bottom end be provided with drain valve.
8. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the feed supplement pipe
Road entrance is separately connected peristaltic pump.
9. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the probe tube
Road and bioreactor junction are equipped with sampling valve.
10. a kind of bioreactor according to claim 1 online disinfection system in situ, it is characterised in that: the tank bottom
Blowing pipeline and bioreactor junction are provided with bottom valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201821574677.6U CN209065899U (en) | 2018-09-26 | 2018-09-26 | Bioreactor online disinfection system in situ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821574677.6U CN209065899U (en) | 2018-09-26 | 2018-09-26 | Bioreactor online disinfection system in situ |
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| Publication Number | Publication Date |
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| CN209065899U true CN209065899U (en) | 2019-07-05 |
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ID=67093417
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| CN201821574677.6U Active CN209065899U (en) | 2018-09-26 | 2018-09-26 | Bioreactor online disinfection system in situ |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113577322A (en) * | 2021-08-20 | 2021-11-02 | 华东理工大学青岛创新研究院 | Bioreactor in-situ steam sterilization device and use method |
| CN113999767A (en) * | 2021-11-02 | 2022-02-01 | 安及义实业（上海）有限公司 | Stainless steel bioreactor for mammalian cell culture and use method thereof |
| CN118059271A (en) * | 2024-04-18 | 2024-05-24 | 上海数郜机电有限公司 | Tube-tank separation steam sterilization system |
-
2018
- 2018-09-26 CN CN201821574677.6U patent/CN209065899U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113577322A (en) * | 2021-08-20 | 2021-11-02 | 华东理工大学青岛创新研究院 | Bioreactor in-situ steam sterilization device and use method |
| CN113577322B (en) * | 2021-08-20 | 2023-11-03 | 华东理工大学青岛创新研究院 | Bioreactor in-situ steam sterilization device and use method |
| CN113999767A (en) * | 2021-11-02 | 2022-02-01 | 安及义实业（上海）有限公司 | Stainless steel bioreactor for mammalian cell culture and use method thereof |
| CN118059271A (en) * | 2024-04-18 | 2024-05-24 | 上海数郜机电有限公司 | Tube-tank separation steam sterilization system |
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Effective date of registration: 20221026 Address after: 226200 No.500, Linyang Road, Qidong Economic Development Zone, Nantong City, Jiangsu Province Patentee after: Wotisi (Nantong) Biotechnology Co.,Ltd. Address before: 215000 No.81 Suli Road, Wuzhong District, Suzhou City, Jiangsu Province Patentee before: SUZHOU DIOUYI BIOTECHNOLOGY CO.,LTD. |