CN208146006U - Multifunctional pneumatic power microfluidic control system and batch sampling system - Google Patents
Multifunctional pneumatic power microfluidic control system and batch sampling system Download PDFInfo
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- CN208146006U CN208146006U CN201820438889.5U CN201820438889U CN208146006U CN 208146006 U CN208146006 U CN 208146006U CN 201820438889 U CN201820438889 U CN 201820438889U CN 208146006 U CN208146006 U CN 208146006U
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- 238000005070 sampling Methods 0.000 title claims abstract description 15
- 239000007788 liquid Substances 0.000 claims abstract description 27
- 230000005611 electricity Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 abstract description 19
- 238000012864 cross contamination Methods 0.000 abstract description 2
- 238000002474 experimental method Methods 0.000 description 11
- 230000006837 decompression Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000000694 effects Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000016 photochemical curing Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
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Abstract
The utility model discloses Multifunctional pneumatic power microfluidic control system and batch sampling systems；Multifunctional pneumatic power microfluidic control system, including gas source, the outlet pipe of gas source are equipped with pressure reducing valve and pressure switch, and the pipeline after pressure switch is divided into a plurality of branch, and every branch road is equipped with automatic Regulation module；The outlet conduit of each automatic Regulation module connects at least two branches, and every branch road is equipped with a solenoid valve；The solenoid valve of a branch road connects the air inlet of the first liquid container by pipeline in a plurality of branch of the outlet conduit connection of each automatic Regulation module, and the liquid outlet conduit of the first liquid container connects micro-fluidic chip by check valve；The automatic Regulation module and solenoid valve are all connect with control panel.Help that can be simple and convenient by check valve realizes that the wink of microfluid stops, and effectively prevent the cross contamination of fluid.Continuous sample introduction both may be implemented using Multifunctional pneumatic power microfluidic control system or batch sampling may be implemented.
Description
Technical field
The utility model relates to microfluidic art more particularly to Multifunctional pneumatic power microfluidic control system and interval into
Sample system.
Background technique
Microflow control technique is referred to using micro-meter scale line treatment or manipulation minute fluid (volume be nanoliter to A Sheng)
System involved in Science and Technology, be one be related to chemistry, fluid physics, microelectronics, new material, biology and biology doctor
Learn the emerging cross discipline of engineering.Because have many characteristics, such as micromation, it is integrated, intelligent, micro fluidic device is commonly known as
Micro-fluidic chip, also referred to as chip lab and micro-total analysis system.
Microfluidic analysis chip is that mainstream technology is diagnosed by bed of new generation, and can directly provide at one's side in checked object fast has
The biochemical indicator of effect makes on-site test, diagnosis and treatment become a continuous process, can greatly improve medical outcome；
Micro-fluidic reaction chip is microreactor most important so far using drop as representative, and in high-flux medicaments sifting, fluorescence is compiled
Code microballoon preparation, the fields such as unicellular sequencing show huge power.
It is the key that realize chip functions to being precisely controlled for microfluid in microflow control technique.At present in micro-fluidic reality
Most popular in testing is to push fluid to enter chip using plunger pump, and the defect of this method is to be injected the continuous sample introduction time
The limitation and operation of pump volume are relative complex.Some experiments, such as need to make in chip in preparing photocuring microballoon experimentation
Fluid realization stops in wink, and pushes fluid realization to stop in wink to be impossible using syringe pump, even if after syringe pump stops working, injection
Can all there be certain residual pressure in the syringe and experimental channel of pump, due to fluid flow very little, residual pressure can still be pushed away
Hydrodynamic body continues to flow.Therefore, the microfluid that one kind is compact-sized, has excellent performance, is easy to operate, multiple functions can be achieved is integrated
Control system is very necessary.
Utility model content
The purpose of this utility model be exactly to solve the above-mentioned problems, provide Multifunctional pneumatic power microfluidic control system and
It has a rest sampling system, compact-sized, the pneumatic microfluidic control system that has excellent performance, is easy to operate, multiple functions can be achieved.
To achieve the goals above, the utility model adopts the following technical solution：
Multifunctional pneumatic power microfluidic control system, characterized in that including gas source, the outlet pipe of gas source is equipped with pressure reducing valve
And pressure switch, the pipeline after pressure switch are divided into a plurality of branch, every branch road is equipped with automatic Regulation module；
The outlet conduit of each automatic Regulation module connects at least two branches, and every branch road is equipped with a solenoid valve；
The solenoid valve of a branch road passes through pipeline in a plurality of branch of the outlet conduit connection of each automatic Regulation module
The air inlet of the first liquid container is connected, the liquid outlet conduit of the first liquid container connects micro-fluidic chip by check valve；
The automatic Regulation module and solenoid valve are all connect with control panel.
The pressure switch connects decompression protection valve.
Pipeline after the pressure switch is divided into four branches.
The solenoid valve being capable of positive/negative-pressure double control.
It is capable of the pneumatic microfluidic control system of batch sampling, using a kind of Multifunctional pneumatic power microfluidic control system
System, the micro-fluidic chip connect the air inlet of second liquid container, the liquid outlet conduit of second liquid container by pipeline
It is connected to another described solenoid valve of the branch road of the outlet conduit connection of corresponding automatic Regulation module.
Another kind is capable of the pneumatic microfluidic control system of batch sampling, using a kind of Multifunctional pneumatic power miniflow
The output channel of body control system, the micro-fluidic chip is equipped with pinch valve.
The beneficial effects of the utility model：
Each parameter, which is integrated on control panel, in Multifunctional pneumatic power microfluidic control system realizes visual integration, in system
The settable bound of pressure switch by pressure control in a certain range, can guarantee the safety of operator.
Help that can be simple and convenient by check valve realizes that the wink of microfluid stops, and effectively prevent the cross contamination of fluid.
Continuous sample introduction both may be implemented using Multifunctional pneumatic power microfluidic control system or batch sampling may be implemented.
Detailed description of the invention
Fig. 1 is the schematic diagram that Multifunctional pneumatic power microfluidic control system is used for continuous sample introduction；
Fig. 2 be without pinch valve being capable of batch sampling Multifunctional pneumatic power microfluidic control system schematic diagram；
Fig. 3 be with pinch valve being capable of batch sampling Multifunctional pneumatic power microfluidic control system schematic diagram.
Wherein, 1. check valve, 2. pinch valves, 3. first liquid containers, 4. second liquid containers.
Specific embodiment
The utility model is described in further detail with embodiment with reference to the accompanying drawing.
As shown in Figure 1, Multifunctional pneumatic power microfluidic control system, including gas source, the outlet pipe of gas source are equipped with decompression
Valve and pressure switch, the pipeline after pressure switch are divided into four branches, and every branch road is equipped with automatic Regulation module, respectively
Automatic Regulation module one, automatic Regulation module two, automatic Regulation module three and automatic Regulation module four；
The outlet conduit of each automatic Regulation module connects two branches, and every branch road is equipped with a solenoid valve, respectively
For solenoid valve one, solenoid valve two ... solenoid valve eight；
Each automatic Regulation module outlet conduit connection a plurality of branch in a branch road solenoid valve (as shown in figure 1
Solenoid valve one) air inlet of the first liquid container 3 is connected by pipeline, the liquid outlet conduit of the first liquid container passes through list
Micro-fluidic chip is connected to valve 1；
The automatic Regulation module and solenoid valve are all connect with control panel.
The gas source can need autonomous selection according to experiment；
The control panel is touch screen, and the parametric variable for needing to be arranged in experiment has opening for each automatic Regulation module
It opens, the stopping of each automatic Regulation module, the pressure value of each automatic Regulation module, the unlatching of each solenoid valve, each electromagnetism
The opening time and dwell time of the stopping of valve and each solenoid valve, all these parameters are integrated in described by configuration software
On control panel, Multifunctional pneumatic power microfluidic control system can be realized by changing corresponding parameter setting on the control panel
Control to each access microfluid；
The pressure reducing valve is used to adjust the pressure of entire control system；
The pressure switch is used to show the pressure value of the control system, and the pressure switch can be set in pressure
When lower limit, i.e. system pressure are more than the upper limit of the pressure switch, the decompression protection valve, which automatically opens, is setting pressure control
Determine in range, when system pressure is in the setting range of the pressure switch, the decompression protection valve is remained turned-off；
The automatic Regulation module is a kind of proportioning valve that the continuous control to pressure is realized in a manner of automatically controlled, and valve port can be with
Any angle is opened as needed, is thus controlled the size of pressure, is met different experiment demands；
The solenoid valve has the function of positive/negative-pressure double control, can be with finer control loine pressure, its effect
The shutdown of gas circuit is controlled, 2 solenoid valves connect 1 automatic Regulation module；
The effect of the check valve 1 be prevented in the case where closing same gas circuit solenoid it is micro- in micro-fluidic chip
Fluid reflux achievees the purpose that make fluid wink in chip to stop.
Multifunctional pneumatic power microfluidic control system, it can be achieved that multiple functions pneumatic microfluidic control system, more function
It can microfluidic control system include pneumatically gas source, control panel, pressure reducing valve, pressure switch, decompression protection valve, 4 automatic Regulations
Module, 8 solenoid valves and check valve.
When continuous sample introduction, the system can at most carry out 8 groups of different experiments simultaneously, as shown in Figure 1.
The continuous sample introduction control method of the Multifunctional pneumatic power microfluidic control system, including：
It include the unlatching of each automatic Regulation module, each automatic Regulation module by the parameter that the control panel is arranged
Stopping, the pressure value of each automatic Regulation module, the unlatching of each solenoid valve, the stopping of each solenoid valve and each electromagnetism
The opening time of valve and dwell time；
Pass through the pressure of the decompression valve regulation whole system；
The pressure value of the control system is shown by the pressure switch, and pressure can be arranged by the pressure switch
Power bound；
The continuous control to pressure, the valve port of automatic Regulation module are realized in a manner of automatically controlled by the automatic Regulation module
Any set angle is opened as needed, is thus controlled the size of pressure, is met different experiment demands；
By the solenoid valve control loine pressure, the shutdown of gas circuit can be controlled；
The check valve prevents the microfluid in micro-fluidic chip from flowing back in the case where closing same gas circuit solenoid,
Achieve the purpose that make fluid wink in chip to stop.
There are two types of control mode, two embodiments presented below when batch sampling.
Embodiment one
The first control mode is as shown in Fig. 2, be capable of the pneumatic microfluidic control system of batch sampling, using described one
Kind Multifunctional pneumatic power microfluidic control system, the micro-fluidic chip connect the air inlet of second liquid container 4 by pipeline, the
The liquid outlet conduit of two liquid containers is connected to the another of the branch road of the outlet conduit connection of corresponding automatic Regulation module
A solenoid valve.
The control method of the control system, including：
It include the unlatching of each automatic Regulation module, each automatic Regulation module by the parameter that the control panel is arranged
Stopping, the pressure value of each automatic Regulation module, the unlatching of each solenoid valve, the stopping of each solenoid valve and each electromagnetism
The opening time of valve and dwell time；
Pass through the pressure of the decompression valve regulation whole system；
The pressure value of the control system is shown by the pressure switch, and pressure can be arranged by the pressure switch
Power bound；
The continuous control to pressure, the valve port of automatic Regulation module are realized in a manner of automatically controlled by the automatic Regulation module
Any set angle is opened as needed, is thus controlled the size of pressure, is met different experiment demands；
By the solenoid valve control loine pressure, the shutdown of gas circuit can be controlled；
The check valve prevents the microfluid in micro-fluidic chip from flowing back in the case where closing same gas circuit solenoid,
Achieve the purpose that make fluid wink in chip to stop；
The solenoid valve of connection second liquid container, connection the are opened while closing the solenoid valve of the first liquid container of connection
The pressure that pipeline where the solenoid valve of two liquid containers generates reacts on the inertia force that fluid continues flow forward, in addition described
The characteristic that check valve prevents microfluid from flowing back, stops in the wink that two pipelines are implemented in combination with microfluid.
Opens solenoid valve one while closing solenoid valve two, the pressure that one place pipeline of solenoid valve generates can react on
Fluid continues the inertia force of flow forward, in addition the characteristic that check valve prevents microfluid from flowing back, the combination of two pipelines may be implemented micro-
The wink of fluid stops.
Embodiment two
Second of control mode is as shown in figure 3, be capable of the pneumatic microfluidic control system of batch sampling, using described one
The output channel of kind Multifunctional pneumatic power microfluidic control system, the micro-fluidic chip is equipped with pinch valve 2.
The control method of the control system, including：
It include the unlatching of each automatic Regulation module, each automatic Regulation module by the parameter that the control panel is arranged
Stopping, the pressure value of each automatic Regulation module, the unlatching of each solenoid valve, the stopping of each solenoid valve and each electromagnetism
The opening time of valve and dwell time；
Pass through the pressure of the decompression valve regulation whole system；
The pressure value of the control system is shown by the pressure switch, and pressure can be arranged by the pressure switch
Power bound；
The continuous control to pressure, the valve port of automatic Regulation module are realized in a manner of automatically controlled by the automatic Regulation module
Any set angle is opened as needed, is thus controlled the size of pressure, is met different experiment demands；
By the solenoid valve control loine pressure, the shutdown of gas circuit can be controlled；
The check valve prevents the microfluid in micro-fluidic chip from flowing back in the case where closing same gas circuit solenoid,
Achieve the purpose that make fluid wink in chip to stop；
The pinch valve 2, the opening resistance of the pinch valve are opened while closing the solenoid valve of the first liquid container of connection
Broken the access of forward fluid motion, in addition the characteristic that check valve prevents microfluid from flowing back can be realized stopping in wink for microfluid.
A pinch valve 2 is added after micro-fluidic chip, open pinch valve while closing solenoid valve two, pinch valve is beaten
The opening/blocking access of forward fluid motion, in addition the wink of microfluid also may be implemented in the characteristic that check valve prevents microfluid from flowing back
Stop, same principle, by controlling the opening and closing time of other each solenoid valves, pinch valve, the system can be simultaneously
Carry out 4 groups of different experiments；
The different fluid of pressure needed for four kinds can also be passed through for the experiment of multiphase flow mixing, passes through the automatic Regulation
Module adjusts flow velocity needed for pressure meets different pipelines, reaches anticipation experiment effect.
The utility model effectively saves experimental period, greatly improves scientific research efficiency.
It is above-mentioned although specific embodiments of the present invention are described with reference to the accompanying drawings, but it is not practical new to this
The limitation of type protection scope, those skilled in the art should understand that, based on the technical solution of the present invention, ability
Field technique personnel do not need to make the creative labor the various modifications or changes that can be made still in the protection model of the utility model
Within enclosing.
Claims (6)
1. Multifunctional pneumatic power microfluidic control system, characterized in that including gas source, the outlet pipe of gas source be equipped with pressure reducing valve and
Pressure switch, the pipeline after pressure switch are divided into a plurality of branch, and every branch road is equipped with automatic Regulation module；
The outlet conduit of each automatic Regulation module connects at least two branches, and every branch road is equipped with a solenoid valve；
The solenoid valve of a branch road is connected by pipeline in a plurality of branch of the outlet conduit connection of each automatic Regulation module
The liquid outlet conduit of the air inlet of first liquid container, the first liquid container connects micro-fluidic chip by check valve；
The automatic Regulation module and solenoid valve are all connect with control panel.
2. Multifunctional pneumatic power microfluidic control system as described in claim 1, characterized in that the pressure switch connection pressure release is protected
Protect valve.
3. Multifunctional pneumatic power microfluidic control system as described in claim 1, characterized in that the pipeline after the pressure switch
It is divided into four branches.
4. Multifunctional pneumatic power microfluidic control system as described in claim 1, characterized in that the solenoid valve being capable of positive/negative-pressure pair
It controls again.
5. capableing of the pneumatic microfluidic control system of batch sampling, characterized in that multi-functional using one kind described in claim 1
Pneumatic microfluidic control system, the micro-fluidic chip connect the air inlet of second liquid container by pipeline, and second liquid holds
The liquid outlet conduit of device is connected to another described electricity of the branch road of the outlet conduit connection of corresponding automatic Regulation module
Magnet valve.
6. capableing of the pneumatic microfluidic control system of batch sampling, characterized in that multi-functional using one kind described in claim 1
The output channel of pneumatic microfluidic control system, the micro-fluidic chip is equipped with pinch valve.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820438889.5U CN208146006U (en) | 2018-03-29 | 2018-03-29 | Multifunctional pneumatic power microfluidic control system and batch sampling system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820438889.5U CN208146006U (en) | 2018-03-29 | 2018-03-29 | Multifunctional pneumatic power microfluidic control system and batch sampling system |
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| CN208146006U true CN208146006U (en) | 2018-11-27 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112246292A (en) * | 2020-10-27 | 2021-01-22 | 深圳睿思生命科技有限公司 | Microfluid implementation device for controlling gas-liquid linkage |
| CN114632556A (en) * | 2020-12-15 | 2022-06-17 | 深圳先进技术研究院 | Universal fluid control system and control method |
-
2018
- 2018-03-29 CN CN201820438889.5U patent/CN208146006U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112246292A (en) * | 2020-10-27 | 2021-01-22 | 深圳睿思生命科技有限公司 | Microfluid implementation device for controlling gas-liquid linkage |
| CN114632556A (en) * | 2020-12-15 | 2022-06-17 | 深圳先进技术研究院 | Universal fluid control system and control method |
| CN114632556B (en) * | 2020-12-15 | 2024-09-13 | 深圳先进技术研究院 | Universal fluid control system and control method |
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Granted publication date: 20181127 |