CN207946434U - Check set group - Google Patents
Check set group Download PDFInfo
- Publication number
- CN207946434U CN207946434U CN201820220432.7U CN201820220432U CN207946434U CN 207946434 U CN207946434 U CN 207946434U CN 201820220432 U CN201820220432 U CN 201820220432U CN 207946434 U CN207946434 U CN 207946434U
- Authority
- CN
- China
- Prior art keywords
- immobilization
- substance
- diaphragm
- liquid sample
- set group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000126 substance Substances 0.000 claims abstract description 222
- 239000007788 liquid Substances 0.000 claims abstract description 100
- 238000007689 inspection Methods 0.000 claims abstract description 54
- 238000001514 detection method Methods 0.000 claims abstract description 48
- 238000003825 pressing Methods 0.000 claims abstract description 13
- 150000001875 compounds Chemical class 0.000 claims description 16
- 238000010276 construction Methods 0.000 claims description 5
- 238000005470 impregnation Methods 0.000 claims description 5
- 238000003475 lamination Methods 0.000 claims description 4
- 238000010521 absorption reaction Methods 0.000 description 21
- 239000000463 material Substances 0.000 description 17
- 239000000427 antigen Substances 0.000 description 15
- 102000036639 antigens Human genes 0.000 description 15
- 108091007433 antigens Proteins 0.000 description 15
- 239000000203 mixture Substances 0.000 description 11
- 239000002245 particle Substances 0.000 description 7
- 238000004040 coloring Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000002994 raw material Substances 0.000 description 5
- 239000012528 membrane Substances 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 3
- 230000001070 adhesive effect Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000003365 glass fiber Substances 0.000 description 3
- 238000005213 imbibition Methods 0.000 description 3
- 239000004745 nonwoven fabric Substances 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 239000004677 Nylon Substances 0.000 description 2
- 239000004695 Polyether sulfone Substances 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 239000003446 ligand Substances 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 229920006393 polyether sulfone Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920000098 polyolefin Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 238000003317 immunochromatography Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 239000002982 water resistant material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model provides a kind of inspection set group that can be positively determined that whether there is or not tested substance.Specifically,Check that set group 11 is the inspection set group for having test strips 21,Test strips 21 are sample drop cushionings 31,Marking substance keeps pad 41,Immobilization diaphragm 51 is linked in sequence according to this,While the liquid sample being added dropwise is unfolded successively towards immobilization diaphragm 51,Tested substance is detected in immobilization diaphragm 51,And there is test strips 21 at least marking substance to keep the position that a part for pad 41 overlaps with a part for immobilization diaphragm 51,The inspection set group 11 has the press section 910 pressed the part on the direction orthogonal with liquid sample expansion direction in the position,The basin of liquid sample expansion in immobilization diaphragm 51,It is also the basin P other than the basin R that the liquid sample immediately below the position of the pressing of pressed portion 910 is unfolded simultaneously,It can be from the external detection for confirming tested substance.
Description
Technical field
The utility model is related to a kind of inspection set groups.
Background technology
Whether judge in the detection sample containing determinands such as bacterium or viruses as the detection sample such as saliva is taken
The device of matter, such as disclose immunochromatography device (referring for example to Japanese Patent Laid-Open 2005-37384 bulletins).
The device is to sandwich the test strips including sample addition component, label holding member, chromatographic grade membrane carrier etc.
In box body, by be added dropwise to the sample add the sample-feed of component to label holding member and become label through coloring
After particle (mark substance) is incorporated into substance to be measured, makes the antibody capture being fixed on chromatographic grade membrane carrier and accumulate the combination
Object determines whether the substance to be measured by estimating as a result,.
In this device, a pair of of the box body for clamping test strips it is opposite to position be provided with protrusion, utilize the protrusion
Make sample addition component and label holding member contiguity, it is effective thereby, it is possible to which the sample of the sample addition component will be added dropwise to
It supplies to rate to label holding member, to make mark substance certainly be incorporated into substance to be measured.
Utility model content
The utility model project to be solved
However, in previous device as described above, the mark substance in label holding member is held in sometimes in color
A large amount of expansion quickly in spectrum membrane carrier.Therefore, in the case where a large amount of expansion occur, have a large amount of mark substances
Coloring be mistakenly considered the tendency of the result arrived by the antibody capture on chromatographic grade membrane carrier, although to have be not present it is measured
Substance, but lead to the worry of the misinterpretation as there are substance to be measured.
The utility model is completed based on situation as above, its purpose is to provide one kind can positively determine that whether there is or not
The inspection set group of tested substance (substance to be measured).
Solve the technological means of project
The utility model is related to：
(1) a kind of inspection set group, has test strips, the test strips be sample drop cushioning, marking substance keep pad and
Immobilization diaphragm is linked in sequence according to this, and the sample drop cushioning is for being added dropwise the liquid sample for including tested substance, the mark
Note compound quality guarantee holds pad impregnation and is selectively incorporated into the tested substance and becomes the marking substance of label, described solid
Surely changing diaphragm has the fixed immobilization substance of tested substance that will be combined with the marking substance, and in the institute being added dropwise
While stating liquid sample and be unfolded successively towards the immobilization diaphragm, the tested substance is detected in the immobilization diaphragm；
And the inspection set group is characterized in that：
The test strips have a part of phase mutual respect of at least part and immobilization diaphragm of marking substance holding pad
The position of conjunction,
The inspection set group has press section, and the press section in the position of the coincidence with the liquid sample to being unfolded
A part on the orthogonal direction in direction is pressed,
The basin of liquid sample expansion in the immobilization diaphragm while being also to be pressed by the press section
Basin other than the basin of liquid sample expansion immediately below position, can be from the external inspection for confirming the tested substance
It surveys；
(2) the inspection set group recorded according to (1), wherein press section are with to overlapping in position and liquid sample
The mode that both ends on the orthogonal direction of expansion direction are pressed is arranged；
(3) the inspection set group recorded according to (1) or (2), wherein marking substance, which keep padding having, includes label
Compound matter contains part adjoining containing part and with this and does not contain part, sample drop not comprising the marking substance
Cushioning is connect with the part of not containing, and described at least part containing part is connect with immobilization diaphragm；
(4) the inspection set group recorded according to (1) or (2), wherein it is the one of at least sample drop cushioning to overlap position
Partly, marking substance keeps the part padded and a part for immobilization diaphragm according to the construction of the sequential lamination；
(5) a kind of inspection set group, has：1st box body；And
2nd box body configures in such a way that interval test strips and the 1st box body are opposite and the test strips is clamped；And
Press section be with to overlap position in the direction orthogonal with liquid sample expansion direction on a part carry out by
The mode of pressure is set to the 1st and/or the 2nd box body；
(6) the inspection set group recorded according to (5) has the detection to confirm tested substance from outside
Window portion, and
The window portion be configured at the 1st and/or the 2nd box body in face of the position of immobilization diaphragm and meanwhile be also in face of from quilt
The position in the basin other than the basin of the underface of the liquid sample expansion of the position outflow of press section pressing；And
(7) a kind of method is using the detection method for the tested substance for checking set group, which has test paper
Item, which is sample drop cushioning, marking substance keeps padding and immobilization diaphragm is linked in sequence according to this, the sample
Pad is added dropwise and keeps pad impregnation to be selectively incorporated into for the liquid sample for including tested substance, the marking substance is added dropwise
The tested substance and as label marking substance, the immobilization diaphragm have will be combined with the marking substance
The fixed immobilization substance of tested substance, and opened up successively towards the immobilization diaphragm in the liquid sample being added dropwise
While opening, the tested substance is detected in the immobilization diaphragm；And the detection method is characterized in that：
The test strips have one of the part that at least described marking substance holding is padded and the immobilization diaphragm
Divide the position to overlap,
The inspection set group has press section, and the press section in the position of the coincidence with the liquid sample to being unfolded
A part on the orthogonal direction in direction is pressed,
The basin of liquid sample expansion in the immobilization diaphragm while being also to be pressed by the press section
Basin other than the basin of liquid sample expansion immediately below position, can be from the external inspection for confirming the tested substance
It surveys.
So-called " test strips " in addition, in the present specification, it includes that sample drop cushioning, marking substance keep pad, solid to refer to
Surely change diaphragm etc. and succession of parts that when sample is normal for liquid circulates.In addition, so-called " position of pressed portion pressing just under
Basin other than the basin of the liquid sample expansion of side ", refers to the expansion the liquid sample that arrow indicates as such as shown in Fig. 3
The immobilization diaphragm 51 of underface (downstream) on direction by the position of protrusion 911 (press section 910) pressing and positioned at the position
The region P in the immobilization diaphragm 51 other than region R (netted shadow part) under interior vertical view.In addition, in Fig. 3, according to respective
Position relationship, L1 indicate region R width, L2 indicate region P width, L3 indicate window portion 915 width.In addition, so-called
" window portion ", refer to include the through hole being physically open and can via specific component from external observation or detecting whether there is or not
The concept at both positions of tested substance.
In addition, " the sample drop cushioning " and " marking substance keeps pad " in this specification is functional difference after all, not
Must each function will be made of individual component.For example, " the sample drop cushioning " in this specification and " marking substance holding
Pad " is the concept for including unitary member, which has the area for the liquid sample comprising tested substance is added dropwise
Domain and impregnation are selectively incorporated into the region of tested substance and the marking substance as label.
In addition, in the present specification, so-called " at least one of a part for marking substance holding pad and immobilization diaphragm
Divide and overlap ", it is such a concept, that is, be not limited to marking substance and pad is kept directly to be overlapped with immobilization diaphragm
Form, but include that marking substance keeps pad to be overlapped different from the other component of these components with immobilization diaphragm interval
Form.
The effect of utility model
The utility model can provide a kind of inspection set group that can be positively determined that whether there is or not tested substance.
Description of the drawings
Fig. 1 is the outline longitudinal section for the 1st embodiment for indicating the utility model.
Fig. 2 is the approximate vertical view of Fig. 1.
Fig. 3 is the partial enlargement approximate vertical view at the position for the window portion for illustrating the utility model.
Fig. 4 is the approximate vertical view for the variation for indicating Fig. 2.
Fig. 5 is the outline longitudinal section for the 2nd embodiment for indicating the utility model.
Fig. 6 is the approximate vertical view of Fig. 5.
Fig. 7 is the outline longitudinal section for the 3rd embodiment for indicating the utility model.
Fig. 8 is the approximate vertical view of Fig. 7.
The explanation of reference numeral：
The gaps g
11,12,13 set group is checked
21,22,23 test strips
31 sample drop cushionings
41,42,43 marking substances keep pad
42a contains part
42b does not contain part
51 immobilization diaphragms
61 absorption pads
71 liner plates
81,83 the 1st box body
91,93 the 2nd box body
910,920,930 press section
915 window portions.
Specific implementation mode
Check set group
The inspection set group of the utility model has test strips, which is sample drop cushioning, marking substance holding pad
And immobilization diaphragm is linked in sequence according to this, the sample drop cushioning is for being added dropwise the liquid sample for including tested substance, institute
Stating marking substance keeps pad impregnation to be selectively incorporated into the tested substance and as the marking substance of label, institute
Stating immobilization diaphragm has the fixed immobilization substance of tested substance that will be combined with the marking substance, and is being added dropwise
Liquid sample while be unfolded successively towards the immobilization diaphragm, detect the detected material in the immobilization diaphragm
Matter；And the inspection set group is characterized in that：There is the test strips at least marking substance to keep the part padded and fixation
Change the position that a part for diaphragm overlaps, the inspection set group has press section, and the press section is in the coincidence position
The direction orthogonal with the liquid sample expansion direction on a part pressed, in the immobilization diaphragm described in
The basin of liquid sample expansion at the same be also the liquid sample expansion immediately below the position that is pressed by the press section stream
Basin other than domain, can be from the external detection for confirming the tested substance.
Hereinafter, the 1st~the 3rd embodiment of the inspection set group is illustrated with reference to attached drawing, but the utility model is not
Only it is defined in the embodiment recorded in the attached drawing.
1st embodiment
Fig. 1 is the outline longitudinal section for the 1st embodiment for indicating the utility model.In addition, the outline that Fig. 2 is Fig. 1 is bowed
View.As shown in Figures 1 and 2, which includes diagrammatically：It is kept with sample drop cushioning 31, marking substance
Test strips 21, liner plate 71, the 1st box body 81 and the 2nd box body 91 of pad 41, immobilization diaphragm 51 and absorption pad 61.
Test strips 21 be sample drop cushioning 31, marking substance keep pad 41, immobilization diaphragm 51 and absorption pad 61 according to
This is linked in sequence, while the liquid sample being added dropwise is unfolded successively towards immobilization diaphragm 51, in the immobilization diaphragm 51
Detect tested substance.
Sample drop cushioning 31 is the component for the liquid sample comprising tested substance is added dropwise.It is set in the sample drop cushioning 31
It is equipped with the dropwise addition portion 31a for liquid sample is added dropwise.Sample drop cushioning 31 is by keeping pad 41 with following marking substances and fixing
Change diaphragm 51 to be formed by compared with the thick and lower raw material of water imbibition compared to mesh.As the former material for constituting sample drop cushioning 31
Material, such as can enumerate：Nylon, polyether sulfone, polyvinyl alcohol, polyester, glass fibre, polyolefin, cellulose or the mixing by them
Fiber is formed by non-woven fabrics etc..In addition, as tested substance, such as the antigens such as influenza virus can be enumerated etc..
It is to be impregnated with selectively to be incorporated into tested substance and as the marking of label that marking substance, which keeps pad 41,
The component of substance.Marking substance holding pad 41 is the upstream side of liquid sample expansion direction via interface k11 and sample drop
Cushioning 31 contact, be held on following protrusions 912 for being set to the 2nd box body 91 and be set to the 1st box body 81 protrusion 812 it
Between, and throughout test strips 21 entire width direction (direction orthogonal with liquid sample expansion direction) and by the protrusion 812,
912 pressings.The marking substance keeps pad 41 to receive the liquid sample for being added dropwise to sample drop cushioning 31, and makes the liquid-like
Sheet and the marking material mixing being held in marking substance holding pad 41, antigen and antibody are anti-by antigen-antibody as a result,
It answers and combines.In the present embodiment, marking substance keeps pad 41 throughout the entire marking substance and is equably impregnated with.
Marking substance keep pad 41 be by with the sample drop cushioning 31 compared with mesh compared with carefully and the higher original of water imbibition
Material is formed by.Thereby, it is possible to make liquid sample certainly be moved to marking substance from sample drop cushioning 31 to keep pad 41.
The raw material of pad 41 are kept as marking substance is constituted, such as can be enumerated：Nylon, polyether sulfone, polyvinyl alcohol, polyester, glass
Fiber, polyolefin, cellulose are formed by non-woven fabrics etc. by their composite fibre.
As marking substance, as long as being selectively incorporated into tested substance and through coloring, then it is not particularly limited, such as
It can enumerate：It is physical or be chemically combined with the examination with insoluble carrier particle such as gold colloid, Pt colloids, colored particles, fluorescent particles,
The substance etc. of enzyme tagged ligand, Fluorescein labeled ligand etc..As the specific example of the marking substance, such as combination can be illustrated
There is the antibody etc. of colored particles.
Immobilization diaphragm 51 is the portion with the fixed immobilization substance of tested substance that will be combined with marking substance
Part.There is the immobilization diaphragm 51 marking substance a part for pad 41 and a part for immobilization diaphragm 51 to be kept to overlap
Position, specifically, the upstream side of liquid sample expansion direction keeps pad 41 to contact via interface k12 and marking substance.
The immobilization diaphragm 51 is received keeps the liquid sample mixed in pad 41 with marking substance and by its court in marking substance
It is unfolded to absorption pad 61.
Specifically, immobilization diaphragm 51 be by with the marking substance keep pad 41 compared to mesh relatively carefully and water imbibition
Higher raw material are formed by.Thereby, it is possible to make liquid sample keep pad 41 to be certainly moved to fixation from marking substance
Change diaphragm 51.As the raw material of composition immobilization diaphragm 51, such as can enumerate：The porosity being made of nitrocellulose etc. is former
Material, the fiber raw material etc. being made of polyester etc..
In addition, being provided with to detect the detection zone 51a of tested substance in immobilization diaphragm 51.In detection zone 51a
It is fixed with immobilization substance, the immobilization substance is selectively incorporated into tested substance and is fixed on the tested substance
Detection zone 51a.Herein, the tested substance through immobilization it is as described above as be combined with marking substance.Therefore, by that will be detected
It surveys substance and is fixed on detection zone 51a, the marking substance through coloring can be accumulated in detection zone 51a, so as to pass through
Marking substance is detected with range estimation identification color or using detection device to determine whether tested substance.As the immobilization
Substance, such as antibody can be enumerated etc..
It as the shape of detection zone 51a, is not particularly limited, such as can be as shown in Fig. 2, being arranged to edge and immobilization diaphragm
The orthogonal direction of 51 sample expansion direction is extended band-like.Thereby, it is possible to be easy and certainly judged.
In addition, on immobilization diaphragm 51, can be also provided between the detection zone 51a and following absorption pads 61 to
Inform the check plot 51b that liquid sample arrived.In this case, for example, by the way that control is fixed on fixed film with substance
Piece 51 and in contrast area 51b, and make selectively to be incorporated into the control substance and combine markd control mark
Note compound matter is impregnated in marking substance and keeps in pad 41.Compound is marked with use is compareed by the liquid sample being added dropwise as a result,
The mixture reaches check plot 51b after matter mixing, and so that control marking substance is compareed and fixed with substance, so as to logical
It crosses and confirms liquid sample by detection zone 51a (inspections to estimate identification color or detect marking substance using detection device
It looks into and is being normally carried out).
Absorption pad 61 is at least part of component for absorbing the liquid sample being unfolded in immobilization diaphragm 51.The absorption
Pad 61 is that the upstream side of the absorption pad 61 is contacted via interface k13 with immobilization diaphragm 51, and reception is opened up in immobilization diaphragm 51
Liquid sample opened etc. and absorbed.There is absorption pad 61 by test strips 21, absorption pad 61 can be utilized to absorb liquid-like
This grade and the expansion (flowing) such as promote liquid sample in immobilization diaphragm 51, can make the liquid for being added dropwise to sample drop cushioning 31
Sample etc. is successfully unfolded.
It as the absorption pad 61, as long as a large amount of liquid samples etc. can be absorbed, is then not particularly limited, such as filter can be used
Paper is formed by non-woven fabrics, absorbent polymer polymer sheet etc. by glass fibre etc..
Liner plate 71 is set between test strips 21 and the 1st box body 81, will constitute sample drop cushioning 31, the label of test strips 21
Compound quality guarantee is held pad 41, immobilization diaphragm 51 and absorption pad 61 and is integrally fixed.Specifically, the liner plate 71 is by liner plate
71 single side is provided with adhesive phase 71a, and adhesive phase 71a is bonded in the sample drop cushioning 31 for constituting test strips 21, mark
Pad 41, immobilization diaphragm 51 and absorption pad 61 are held in note compound quality guarantee, and described sample drop cushioning 31 etc. is fixed integrally to serve as a contrast
On plate 71.As the formation liner plate 71 and the material of adhesive phase 71a, such as well known water-resistant material can be used etc..This
Sample one has liner plate 71 by the inspection set group 11, can certainly keep each pad.
1st box body 81 loads test strips 21.2nd box body 91 is matched in a manner of interval test strips 21 and 81 opposite direction of the 1st box body
It sets and test strips 21 is clamped.As the material of composition the 1st and the 2nd box body 81,91, such as polypropylene, ABS can be used etc..
Herein, at least part between the liner plate 71 and the 1st box body 81 is provided with gap g.As shown in Figure 1, should
Gap g is to be connected to be arranged by the lower surface of liner plate 71 to be formed in the end of the protrusion 811~813 of the 1st box body 81.Make
For the interval of gap g, it is preferably formed into the degree that will not be spread into the liquid sample etc. of gap g by surface tension.Make
For the interval of gap g, preferably 0.1mm or more, more preferably 0.5mm or more.Thereby, it is possible to inhibit liquid sample to penetrate into examination
Between paper slip 21 and the 1st box body 81, so as to inhibit the loss of the liquid sample, to be detected positively out, whether there is or not be detected
Substance.
2nd box body 91 is provided with press section 910, which only keeps marking substance a part for pad 41
With one on the direction orthogonal with liquid sample expansion direction in the position that a part for immobilization diaphragm 51 overlaps
Divide and is pressed (with reference to Fig. 2).Specifically, press section 910 is formed by protrusion 911 are arranged in the 2nd box body 91, it is described
Protrusion 911 is the side only to be pressed overlapping the both ends on the direction orthogonal with liquid sample expansion direction in position
Formula is arranged.
By being provided with press section 910 in this way, marking substance can be made to keep pad 41 and immobilization diaphragm 51
Contiguity can make liquid sample etc. keep pad 41 to be unfolded to immobilization diaphragm 51 from marking substance really and successfully.In addition,
It is arranged in a manner of pressing the both ends the press section 910 (protrusion 911), it can be relative to expansion direction symmetrically
Pressing overlaps position, so as to make liquid sample be unfolded well towards 61 balance of absorption pad in immobilization diaphragm 51.
In addition, being provided in the 2nd box body 91 putting into liquid sample to the sample input port of the inspection set group 11
914.The position of dropwise addition portion 31a in face of sample drop cushioning 31 of the sample input port 914 in the 2nd box body 91 is open, can
Liquid sample is put into dropwise addition portion 31a via sample input port 914.
In addition, the 2nd box body 91 has to from the window portion 915 of the external detection for confirming tested substance, which matches
It is placed in the position in face of immobilization diaphragm 51 while being also the liquid sample immediately below the position that pressed portion 910 presses
The position of basin P other than the basin R of expansion.As the window portion 915, such as following composition can be used etc.：In 91 shape of the 2nd box body
At there is opening；Configuration makes the component that the fluorescence passes through for the component of visible transparent, when marking substance sends out fluorescence.This
Outside, in the present embodiment, using the window portion 915 for being formed with opening in the 2nd box body 91.
In addition, for more positively determining that whether there is or not the viewpoint of tested substance, preferably by basin R with can not be from outside
Confirm that the mode of the detection of tested substance is covered.As this form, such as can enumerate：1st and/or the 2nd box body can not be distinguished
Know the color of marking substance being unfolded in the R of basin form (such as box body it is opaque, on box body printing word or note
Number or attachment labels etc.) or by hindering to detect the form or stream that the material of marking substance is constituted using detection device
Domain R is obstructed color-identifying or the component (shielding portion other than the 1st and the 2nd box body using detection device detection marking substance
Part) covering form etc..As the material or component of the obstruction detection, such as certain wave necessary to obstruction detection can be enumerated
The long material penetrated or component etc..
Next, to using the detection method of the tested substance of the detection set group 11 of the present embodiment to illustrate.This
Place, illustrates example below：Using antigen as tested substance, using the antibody of colored particles is combined with as mark
Remember compound matter, using antibody as immobilization substance, and has as a contrast with label in marking substance keeps pad 41
The antibody (antibody different from the antibody in immobilization substance) for being combined with colored particles of compound matter, has in the 51b of check plot
There is the antigen (antigens different from the antigen in tested substance) for using substance as a contrast.In addition, as tested substance
Antibody included in antigen and marking substance and as the antigen of tested substance and as the anti-of immobilization substance
Body and the control antibody included in marking substance and as a contrast use substance antigen it is anti-by antigen-antibody respectively
It answers and combines.
First, prepare liquid sample, put into appropriate amount of fluid sample to sample via the sample input port 914 of inspection set group 11
After the dropwise addition portion 31a of this dropwise addition pad 31, which infiltrates into sample drop cushioning 31, and part of it is protected towards marking substance
Hold the expansion of pad 41.
Next, the liquid sample for reaching interface k11 infiltrates into marking substance via interface k11 and keeps in pad 41,
The liquid sample of the infiltration is unfolded towards immobilization diaphragm 51.At this point, liquid sample with containing be immersed in marking substance keep pad 41
In marking substance and control marking material mixing, it is anti-by antigen in the case of in liquid sample including antigen
Precursor reactant is combined with the antibody in marking substance, is opened up in this state towards immobilization diaphragm 51 together with marking substance
It opens.
Next, the liquid sample etc. for reaching interface k12 is infiltrated into via interface k12 in immobilization diaphragm 51.At this point,
Since marking substance keeps pad 41 to be pressed by protrusion 911 with immobilization diaphragm 51 and touch, liquid sample etc. is quickly opened up
It opens to immobilization diaphragm 51.It is unfolded towards absorption pad 61 next, being expanded to liquid sample of immobilization diaphragm 51 etc., leads to successively
Cross the detection zone 51a and check plot 51b for being set to immobilization diaphragm 51.
In detection zone 51a, the antigen combined with marking substance in the case of including antigen in liquid sample is further
By be impregnated in the immobilization substance of detection zone 51a in conjunction with by fix.Although being fixed by this by making the label compound through coloring
Matter is accumulated in detection zone 51a, but the basin of liquid sample expansion of the inspection set group 11 in immobilization diaphragm 51 is also simultaneously
Pressed portion 910 press position immediately below liquid sample expansion basin R other than basin P, can via window portion 915 from
Outside confirms the detection of (range estimation is confirmed using detection device) tested substance, therefore can determine nonantigenic.
On the other hand, the part of liquid sample etc. reaches check plot 51b by detection zone 51a, in marking substance
Keep being mixed in pad 41 control of liquid sample with marking substance in the 51b of check plot fixed control combined with substance
And immobilization.At the same time, control marking substance is accumulated in check plot 51b, therefore, it is possible to by via window portion 915 with
Range estimation confirms check plot 51b, and whether there is or not colors to recognize liquid sample by detection zone 51a (inspection is being normally carried out).It connects down
Come, the part of liquid sample etc. is absorbed by the 51b of check plot by absorption pad 61.
Incidentally, when liquid sample etc. keeps pad 41 to be expanded in immobilization diaphragm 51 from marking substance, label
The a large amount of expansion quickly in immobilization diaphragm 51 sometimes of compound matter.The phenomenon is easy in liquid sample etc. finally by interface
It is generated when k12.If generating the phenomenon, the higher specific region of marking material concentration can be moved in immobilization diaphragm 51
It is dynamic, it is also possible to lead to misinterpretation.That is, although substance to be measured (antigen) is not present, cause in immobilization diaphragm 51
The coloring as there are substance to be measured (antigen).
However, since the inspection set group 11 has to overlapping on the direction orthogonal with liquid sample expansion direction in position
The press section that is pressed of a part, the basin of the liquid sample expansion in immobilization diaphragm 51 while being also to be pressed
Basin P other than the basin R of liquid sample expansion immediately below the position that portion 910 presses can confirm detected material from outside
The detection of matter, therefore the stabilization of the marking substance of the pressing of press section 910 can be at least not accompanied by from external observation
The basin of expansion, so as to positively determine that whether there is or not tested substances.In addition, thus it is speculated that make liquid-like because pressing overlaps position
Originally the reason of waiting a moment sub a large amount of expansion is：The easy position being pressed being stranded in the k12 of interface such as liquid sample,
Liquid sample of the delay etc. finally by when can be unfolded quickly (releasing).
2nd embodiment
Fig. 5 is the outline longitudinal section for the 2nd embodiment for indicating the utility model.In addition, the outline that Fig. 6 is Fig. 5 is bowed
View.As shown in Figures 5 and 6, which includes diagrammatically：It is kept with sample drop cushioning 31, marking substance
Test strips 22, liner plate 71, the 1st box body 81 and the 2nd box body 91 of pad 42, immobilization diaphragm 51 and absorption pad 61.
In the present embodiment, marking substance keeps the composition of pad 42 different from the 1st embodiment.Further, since sample
Composition and the 1st embodiment party of this dropwise addition pad 31, immobilization diaphragm 51, absorption pad 61, liner plate 71, the 1st box body 81 and the 2nd box body 91
These components of case are identical, therefore simultaneously description is omitted to same section mark the same symbol.In addition, due to marking compound
The composition that pad 42 is held in quality guarantee is the marking substance with the 1st embodiment other than marking substance is different containing part
It keeps pad identical, therefore omits the detailed description other than the explanation containing part.
It is to be impregnated with selectively to be incorporated into tested substance and as the marking of label that marking substance, which keeps pad 42,
The component of substance.The marking substance of the present embodiment keep pad 42 have comprising marking substance containing part 42a and
To contain part 42a adjacent and do not contain part 42b not comprising marking substance with this, sample drop cushioning 31 and does not contain part
42b connections, at least part containing part 42a are connect with immobilization diaphragm 51.
As long as the marking substance of the present embodiment keep pad 42 be at least interface k21 it is whole with do not connect containing part 42b
It touches.In addition, marking substance keeps containing the part 42a and not ratio containing part 42b of the marking substance in pad 42
Rate (such as volume ratio etc.) is then not particularly limited as long as meeting the composition, can use various ratios.
Next, to using the detection method of the tested substance of the detection set group 12 of the present embodiment to illustrate.This
Outside, it is to be illustrated to the part for playing the effect different from the effect of detection method illustrated in the 1st embodiment herein.
First, appropriate amount of fluid sample is put into sample drop cushioning 31 via the sample input port 914 of inspection set group 12
After dropwise addition portion 31a, which infiltrates into sample drop cushioning 31, and part of it keeps pad 42 to be unfolded towards marking substance.
Next, the liquid sample for reaching interface k21 is expanded to marking substance via interface k21 and keeps in pad 42,
The liquid sample one side of the expansion and marking substance and compare with marking material mixing, on one side with these substances together direction
Immobilization diaphragm 51 is unfolded.At this point, the inspection set group 12 is that only marking substance keeps not including marking substance in pad 42
Do not contacted with sample drop cushioning 31 containing part 42b, therefore, marking substance will not be detained in the k21 of interface, will not occur because
Marking substance caused by the delay of interface k21 is largely unfolded quickly, correspondingly, can inhibit the erroneous judgement of tested substance
It is fixed, it can more positively determine that whether there is or not tested substances.
Next, the liquid sample etc. for reaching interface k22 is expanded to via interface k22 in immobilization diaphragm 51, hereinafter,
It is carried out in a manner of identical with the 1st embodiment.
3rd embodiment
Fig. 7 is the outline longitudinal section for the 3rd embodiment for indicating the utility model.In addition, the outline that Fig. 8 is Fig. 7 is bowed
View.As shown in Figures 7 and 8, which includes diagrammatically：It is kept with sample drop cushioning 31, marking substance
Test strips 23, liner plate 71, the 1st box body 83 and the 2nd box body 93 of pad 43, immobilization diaphragm 51 and absorption pad 61.
In the present embodiment, sample drop cushioning 31, marking substance keep the structure that pad 43 and immobilization diaphragm 51 overlap
1 embodiments of Cheng Yu are different.Further, since each component of the composition and the 1st embodiment of each component such as sample drop cushioning 31
Composition it is identical, therefore these components illustrate quote the 1st embodiment explanation and omit.
In the present embodiment, the coincidence position of test strips 23 be at least a part for sample drop cushioning 31, label compound
Quality guarantee hold pad 43 a part and immobilization diaphragm 51 a part according to the sequential lamination construction.In the present embodiment,
The inspection set group 13 is that lamination has immobilization diaphragm 51, marking substance to keep pad 43 and sample drop cushioning 31 on liner plate 71,
The component of 3 layers of construction is integrally held between protrusion 831 and protrusion 931 (press section 930).
Next, to using the detection method of the tested substance of the detection set group 13 of the present embodiment to illustrate.This
Outside, it is to be illustrated to the part for playing the effect different from the effect of detection method illustrated in the 1st embodiment herein.
First, appropriate amount of fluid sample is put into sample drop cushioning 31 via the sample input port 914 of inspection set group 13
After dropwise addition portion 31a, which infiltrates into sample drop cushioning 31, and part of it keeps pad 43 to be unfolded towards marking substance.
Next, the liquid sample for reaching interface k31 is expanded to marking substance via interface k31 and keeps in pad 43
Afterwards, on one side with marking substance and compare with marking material mixing, be expanded to immobilization diaphragm 51 via interface k32 on one side
In.At this point, the inspection set group 13, which is sample drop cushioning 31, marking substance holding pad 43 and immobilization diaphragm 51, becomes described 3
Layer construction, and the protrusion 931 for being known as press section 930 integrally presses, therefore, it is possible to make the sample drop cushioning 31 wait with letter
Easy touches with being integrally formed, so as to promote the expansion such as liquid sample with rapid and be detected positively that whether there is or not detected materials
Matter.
Next, the liquid sample etc. for reaching interface k32 is infiltrated into via interface k32 in immobilization diaphragm 51, hereinafter,
It is carried out in a manner of identical with the 1st embodiment.
The detection method of tested substance
The detection method of the tested substance of the utility model has used inspection set group, which has test strips,
The test strips are sample drop cushionings, marking substance keeps padding and immobilization diaphragm is linked in sequence according to this, the sample drop
Cushioning include the liquid sample of tested substance for being added dropwise, and the note compound quality guarantee is held described in pad is impregnated with and is selectively incorporated into
Tested substance and the marking substance for becoming label, the immobilization diaphragm have the quilt that will be combined with the marking substance
The fixed immobilization substance of substance is detected, and be unfolded successively towards the immobilization diaphragm in the liquid sample being added dropwise
Meanwhile detecting the tested substance in the immobilization diaphragm；And the detection method of the tested substance is characterized in that：Institute
Stating test strips, there is at least marking substance to keep the position that a part for pad overlaps with a part for immobilization diaphragm, institute
It states and checks that set group has press section, the press section is to the side orthogonal with the liquid sample expansion direction in the coincidence position
A upward part is pressed, the basin of the liquid sample in immobilization diaphragm expansion while being also by institute
The basin other than the basin of the liquid sample expansion immediately below the position of press section pressing is stated, it can be from described in the confirmation of outside
The detection of tested substance.
Further, since the detailed description of the detection method of the tested substance and the 1st in " checking set group " item are real
The explanation applied in scheme is identical, therefore quotes the explanation and omit explanation herein.
In addition, the utility model is not limited to the composition of the embodiment but is indicated by claims, it is intended that packet
Containing with being had altered in the meaning and range of claims equalization.
For example, in the embodiment described in which, the inspection set group 11~13 to having the 1st and the 2nd box body is illustrated, but
The inspection set group for not having these box bodys is also contained in the range of the utility model intention.As this form, such as can arrange
It lifts and presses the inspection set group of a part etc. for overlapping position using clampings means such as fixtures.
In addition, using the clamping means or curtain-shaped cover member, also use can there are these means or component
Test strips with other box bodys (box body other than the 1st and the 2nd box body) come holding.
In addition, being with to overlapping in position and liquid sample to press section 910,920,930 in the embodiment described in which
Inspection set group 11 that the mode that both ends on the orthogonal direction of expansion direction (width directions of test strips) are pressed is arranged,
12, it 13 is illustrated, but as long as press section is to overlapping one on the direction orthogonal with liquid sample expansion direction in position
Part pressed, then be not particularly limited, for example, be alternatively press section be with the central portion in the width direction to test strips into
The inspection set group that the mode of row pressing is arranged.
In addition, in the embodiment described in which, the inspection set group 11~13 to having absorption pad 61 is illustrated, but as long as
It is added dropwise to liquid sample of sample drop cushioning 31 etc. towards immobilization diaphragm 51 to be successfully unfolded, does not then have the absorption pad 61
Inspection set group be also contained in the utility model be intended in the range of.
In addition, in the embodiment described in which, to sample drop cushioning 31 and marking substance keep pad 41,42 by protrusion 912,
The 922 inspection sets pressed throughout width direction (direction orthogonal with the liquid sample expansion direction) entirety of test strips 21,22
Group 11,12 is illustrated, but presses the width that sample drop cushioning and marking substance keep the position of pad to be alternatively test strips
A part (part on the direction orthogonal with liquid sample expansion direction) on direction.
Among these, keeping padding inspection set group that is whole and being equably impregnated with marking substance throughout marking substance
In the case of, the basin R1 that 940 preference of position of the pressing is illustrated in figure 4 in the underface that liquid sample is unfolded is not arranged
The position of window portion 915.Thereby, it is possible to further decrease because of the label on the interface of sample drop cushioning and marking substance holding pad
Compound matter is detained caused misinterpretation, can more positively determine that whether there is or not tested substances.
In addition, in the embodiment described in which, the inspection set group 11~13 to having liner plate 71 is illustrated, but as long as sample
This dropwise addition pad, marking substance keep pad and immobilization diaphragm to meet the relationship and do not undermine the effect of the utility model, then
Or do not have the inspection set group of liner plate 71.
In addition, in the embodiment described in which, may be contained within the 2nd box body 91,93 to sample input port 914 and window portion 915
Check that set group 11~13 is illustrated, but at least any one inspection set group for being set to the 1st box body among them also includes
In the range of the utility model intention.
Claims (6)
1. a kind of inspection set group, has test strips, which is sample drop cushioning, marking substance holding pad and immobilization
Diaphragm is linked in sequence according to this, and the sample drop cushioning is for being added dropwise the liquid sample for including tested substance, the label compound
Quality guarantee holds pad impregnation and is selectively incorporated into the tested substance and as the marking substance of label, the fixed film
Piece has the fixed immobilization substance of tested substance that will be combined with the marking substance, and in the liquid being added dropwise
While sample is unfolded successively towards the immobilization diaphragm, the tested substance is detected in the immobilization diaphragm；The inspection
Set group is looked into be characterized in that：
There is the test strips at least marking substance a part for pad to be kept to overlap with a part for immobilization diaphragm
Position,
The inspection set group has press section, the press section in the position of the coincidence with the liquid sample expansion direction
A part on orthogonal direction is pressed,
The basin of liquid sample expansion in the immobilization diaphragm while being also the position that is pressed by the press section
Basin other than the basin of the liquid sample expansion of underface, can be from the external detection for confirming the tested substance.
2. inspection set group according to claim 1, which is characterized in that press section is with to overlapping in position and liquid-like
The mode that both ends on the orthogonal direction of this expansion direction are pressed is arranged.
3. inspection set group according to claim 1 or 2, which is characterized in that marking substance, which keeps padding having, includes label
Compound matter contains part adjoining containing part and with this and does not contain part, sample drop not comprising the marking substance
Cushioning is connect with the part of not containing, and described at least part containing part is connect with immobilization diaphragm.
4. inspection set group according to claim 1 or 2, which is characterized in that it is the one of at least sample drop cushioning to overlap position
Partly, marking substance keeps the part padded and a part for immobilization diaphragm according to the construction of the sequential lamination.
5. inspection set group according to claim 1, which is characterized in that it has：1st box body；And
2nd box body configures in such a way that interval test strips and the 1st box body are opposite and the test strips is clamped；And
Side of the press section to be pressed overlapping the part on the direction orthogonal with liquid sample expansion direction in position
Formula is set to the 1st box body and/or the 2nd box body.
6. inspection set group according to claim 5, which is characterized in that it has to confirm tested substance from outside
The window portion of detection, and
The window portion be configured at the 1st and/or the 2nd box body in face of the position of immobilization diaphragm and meanwhile be also in face of from being pressed
The position in the basin other than the basin of the underface of the liquid sample expansion of the position outflow of portion's pressing.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPPCT/JP2017/045028 | 2017-12-15 | ||
| PCT/JP2017/045028 WO2019116527A1 (en) | 2017-12-15 | 2017-12-15 | Testing kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207946434U true CN207946434U (en) | 2018-10-09 |
Family
ID=63699646
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311207583.0A Pending CN117269479A (en) | 2017-12-15 | 2017-12-15 | Inspection kit and method for detecting substance to be detected using inspection kit |
| CN201780097729.7A Pending CN111556968A (en) | 2017-12-15 | 2017-12-15 | Inspection set |
| CN201820220432.7U Active CN207946434U (en) | 2017-12-15 | 2018-02-08 | Check set group |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311207583.0A Pending CN117269479A (en) | 2017-12-15 | 2017-12-15 | Inspection kit and method for detecting substance to be detected using inspection kit |
| CN201780097729.7A Pending CN111556968A (en) | 2017-12-15 | 2017-12-15 | Inspection set |
Country Status (4)
| Country | Link |
|---|---|
| KR (1) | KR102503011B1 (en) |
| CN (3) | CN117269479A (en) |
| TW (1) | TWI782949B (en) |
| WO (1) | WO2019116527A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107807006A (en) * | 2017-10-25 | 2018-03-16 | 上海菲伽生物科技有限公司 | Storage civilian dress for detection of defecating is put |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021015273A1 (en) * | 2019-07-23 | 2021-01-28 | 田中貴金属工業株式会社 | Liquid sample inspection tool |
| JP7373349B2 (en) * | 2019-10-04 | 2023-11-02 | デンカ株式会社 | Immunochromatographic device for extracting and measuring carbohydrate antigens |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3248436B2 (en) * | 1995-09-08 | 2002-01-21 | 富士レビオ株式会社 | Immunoassay device and method |
| US7256053B2 (en) * | 2002-10-24 | 2007-08-14 | Nanogen, Inc. | Diagnostic device for analyte detection |
| JP4425074B2 (en) | 2003-06-30 | 2010-03-03 | シスメックス株式会社 | Immunochromatography device |
| JP4643415B2 (en) | 2005-10-21 | 2011-03-02 | ロート製薬株式会社 | Case for inspection tool and liquid sample inspection tool |
| JP4990692B2 (en) * | 2007-06-22 | 2012-08-01 | 株式会社ビーエル | Immunochromatographic assay and kit |
| JP2010156571A (en) * | 2008-12-26 | 2010-07-15 | Fujifilm Corp | Chromatography device |
| JP6180761B2 (en) * | 2013-03-13 | 2017-08-16 | デンカ生研株式会社 | Inspection kit |
| JP5792859B1 (en) * | 2014-04-04 | 2015-10-14 | 田中貴金属工業株式会社 | Immunochromatographic analysis method |
| JP6254994B2 (en) * | 2014-11-18 | 2017-12-27 | 株式会社ニチレイバイオサイエンス | Inspection kit |
| CN108369228B (en) * | 2015-12-18 | 2020-11-17 | 富士胶片株式会社 | Immunochromatography kit |
| JP6958817B2 (en) * | 2016-03-08 | 2021-11-02 | 国立研究開発法人国立がん研究センター | Anti-TMEM-180 antibody, anti-cancer drug, and cancer testing method |
| CN206096144U (en) * | 2016-10-12 | 2017-04-12 | 艾博生物医药(杭州)有限公司 | Test paper strip and diagnostic device for immunity chromatography |
-
2017
- 2017-12-15 KR KR1020207020309A patent/KR102503011B1/en active IP Right Grant
- 2017-12-15 WO PCT/JP2017/045028 patent/WO2019116527A1/en active Application Filing
- 2017-12-15 CN CN202311207583.0A patent/CN117269479A/en active Pending
- 2017-12-15 CN CN201780097729.7A patent/CN111556968A/en active Pending
-
2018
- 2018-02-06 TW TW107104084A patent/TWI782949B/en active
- 2018-02-08 CN CN201820220432.7U patent/CN207946434U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107807006A (en) * | 2017-10-25 | 2018-03-16 | 上海菲伽生物科技有限公司 | Storage civilian dress for detection of defecating is put |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201927249A (en) | 2019-07-16 |
| KR20200098634A (en) | 2020-08-20 |
| CN111556968A (en) | 2020-08-18 |
| KR102503011B1 (en) | 2023-02-23 |
| WO2019116527A1 (en) | 2019-06-20 |
| TWI782949B (en) | 2022-11-11 |
| TW202306545A (en) | 2023-02-16 |
| CN117269479A (en) | 2023-12-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN207946434U (en) | Check set group | |
| EP0824697B1 (en) | One step immunochromatographic device and method of use | |
| CN101137897B (en) | Dual path immunoassay device | |
| CN1894584B (en) | Device and method for simultaneously carrying out blood group determination, serum cross-check and antibody detection test | |
| US8202487B2 (en) | Multiple analyte assay devices | |
| ATE130682T1 (en) | IMMUNE TEST AND TEST ARRANGEMENT. | |
| CN101467042A (en) | Directed-flow assay device | |
| KR20060059958A (en) | Device and method for simultaneously identifying blood group antigens | |
| KR20210127180A (en) | lateral flow device | |
| US20120003727A1 (en) | Immunoassay Device for Detecting Antibodies and Antigens | |
| KR20120088342A (en) | Diagnostic strip and manufacturing method of the same | |
| KR20150126866A (en) | Examination kit | |
| CN107430120A (en) | Immunologic detection method and the test-strips for it | |
| WO2011102563A1 (en) | Immunoassay device and immunoassay method using same | |
| EP2975407B1 (en) | Examination kit | |
| KR102215916B1 (en) | Apparatus for lateral flow analysis using membrane pattern | |
| TWI858409B (en) | Test kit, and method for testing a substance to be tested using the test kit | |
| CN208833770U (en) | A kind of three joint inspections survey card | |
| JP6777468B2 (en) | Inspection kit | |
| JP4425075B2 (en) | Immunochromatography device | |
| JP6357616B2 (en) | Sheet immunoassay | |
| CN101175996A (en) | Semi-quantitative immunochromatographic device | |
| GB2447296A (en) | Method and apparatus for performing test to locate a chosen analyte | |
| TWI258586B (en) | Immunochemical detection device | |
| KR200394358Y1 (en) | Immunoassay device capable of performing several immunoassays |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20200916 Address after: Tokyo, Japan Patentee after: DENKA Co.,Ltd. Address before: Tokyo, Japan Patentee before: DENKA SEIKEN Co.,Ltd. |