CN207734389U - A kind of structure for nose shaping filling allogeneic decalcification bone - Google Patents
A kind of structure for nose shaping filling allogeneic decalcification bone Download PDFInfo
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- CN207734389U CN207734389U CN201621342369.1U CN201621342369U CN207734389U CN 207734389 U CN207734389 U CN 207734389U CN 201621342369 U CN201621342369 U CN 201621342369U CN 207734389 U CN207734389 U CN 207734389U
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Abstract
The utility model is related to a kind of structures for filling allogeneic decalcification bone for nose shaping, wherein, the structure includes the nasal bone matrix being made by allogeneic decalcification bone, and the nasal bone matrix includes nose, nose pillar, the bridge of the nose, and the bridge of the nose connects nose pillar by nose；There is narrowed changeover portion, the width of the changeover portion to be less than the width of the bridge of the nose between the bridge of the nose and nose；The lower part of the bridge of the nose is made of two shapes that are in the shape of the letter V bridge of the nose section arranged in a crossed manner, and the nasal bone of human body is located between two bridge of the nose sections, to ensure that prosthese will not displacement and abrasion.Advantageous effect is：Pass through the design of bridge of the nose section so that prosthese is in close contact with nasal bone, will not displacement or abrasion；Body fluid can be allowed to flow into hole by the hole on the bridge of the nose makes tissue grow into hole, nose is allowed to be connected with ose implant, prevents ose implant movement, falls off, festers, and the feeling of pain of postoperative patient, this method is prevented to be suitable for androgynous, allograph bone processing.
Description
Technical field
The utility model is related to shaping technique fields, and allogeneic decalcification is filled for nose shaping more particularly, to one kind
The structure of bone.
Background technology
Nasal plastic (lift face) operation is to change the height and form of nose by being implanted into suitable material, be allowed to face other
Position is mutually coordinated, and is the operation of field of orthopedic surgery the most common type.
Medically, there are many kinds of nasal plastic materials, such as medical grade silicon rubber, self cartilage, animal tendon or ligament, varicosity
(polytetrafluoroethylene (PTFE)), sodium hyaluronate etc..The preparation method of bridge of the nose prosthese is also more, wherein self cartilage due to source itself, so
Be not in rejection phenomenon, also not sensitization, but it is moulding relatively difficult in manufacturing process.Using animal tendon, ligament as raw material, because
It is formed and structure is similar to tissue, good biocompatibility, and implantation does not cause immune rejection, can induce tissue again
It is raw, but need to be handled through a series of biochemical technologies, manufacturing process is more complicated.Firm silicone rubber hump nose material because nontoxic,
Histocompatbility is stablized relatively, is main medical prosthesis hump nose material, is easy to moulding in manufacturing process, but silicon rubber implant
Displacement and abrasion are easy to happen after implanting.
Therefore, a kind of appearance of structure for nose shaping filling allogeneic decalcification bone is necessary, makes
Process is convenient, stable structure, is not susceptible to shift and wear.
Utility model content
The utility model provides a kind of structure for nose shaping filling allogeneic decalcification bone, to solve the prior art
Middle manufacturing process is more complicated, the problems such as being easy to happen displacement and wear.
The technical issues of the utility model is solved is realized using following technical scheme：
A kind of structure for nose shaping filling allogeneic decalcification bone, including be made by allogeneic decalcification bone
Nasal bone matrix, the nasal bone matrix includes nose, nose pillar, the bridge of the nose, and the bridge of the nose passes through nose and connects nose pillar；The nose
There is narrowed changeover portion, the width of the changeover portion to be less than the width of the bridge of the nose between beam and nose；
The lower part of the bridge of the nose is made of two shapes that are in the shape of the letter V bridge of the nose section arranged in a crossed manner, and the nasal bone of human body is located at two
Between a bridge of the nose section, to ensure that prosthese will not displacement and abrasion.
The surface of the bridge of the nose is densely covered with numerous holes as a preferred technical solution, by described hole so that prosthese
It with elasticity, can stretch, can be very good fitting nose, hole can allow body fluid to flow into hole and grow tissue, allow
Nose is connected with ose implant, prevents ose implant movement, falls off, festers, prevents the feeling of pain of postoperative patient.
Described hole is through-hole or non through hole as a preferred technical solution,.
Described hole is non through hole as a preferred technical solution, and the bottom of described hole is plane or arc surface.It is described
What hole can be typed it out with laser, laser equipment punched hole, hole periphery is mellow and full, and bottom is one smooth, impulse- free robustness.
The surface for being arranged in the bridge of the nose of described hole rule as a preferred technical solution, described hole and hole
Between spacing it is identical, it is whole very beautiful.
The bore dia of described hole is 0.02mm-0.1mm as a preferred technical solution,；Hole density is 3000-200000
A/cm2。
A kind of preparation method of structure for nose shaping filling allogeneic decalcification bone, includes the following steps：
A bone) is taken, obtains allogeneic cartilage in an aseptic environment；
B it) handles, the allogeneic cartilage of acquirement is subjected to degreasing, decalcification, de- albumen and sterilization treatment successively；
C it) chisels and carves, treated allogeneic cartilage is chiseled and carved into the shape of needs, you can；
The allogeneic cartilage is non-self rib cage, non-Auricular cartilage as a preferred technical solution,.
The concrete processing procedure in step B includes as a preferred technical solution,：
(1) allogeneic cartilage is immersed in chloroform and methyl alcohol mixed liquor body 6-24 hours；
(2) by above-mentioned steps (1), treated that the allogeneic cartilage is added in hydrochloric acid solution, and it is small persistently to stir 8-12
When；
(3) by above-mentioned steps (2), treated that the allogeneic cartilage immerses TritonX-100 and ammonium hydroxide mixed solution
Middle effect 2-72 hours；
(4) by above-mentioned steps (3) treated allogeneic cartilage freeze-drying, sterilization treatment；
Wherein：The volume ratio of chloroform and methanol in the chloroform and methyl alcohol mixed liquor is 1：1；
A concentration of 0.5-0.6mol/L of the hydrochloric acid solution；
The volumn concentration of the TritonX-100 and the TritonX-100 in ammonium hydroxide mixed solution are 0.1%-
2%, the mass percentage of ammonia is 0.3%；
It is described freeze-drying refer to the allogeneic cartilage is put into it is freeze-dried in -72 DEG C~-80 DEG C of freeze dryer
For 24 hours~48h；
The sterilization treatment refers to that will be put into ethylene oxide sterilizing after allogeneic cartilage plastic bag packaging seal
Sterilizing in device, in 480mg/L~520mg/L, sterilising temp is controlled at 38 DEG C~42 DEG C, is gone out for the mass concentration control of ethylene oxide
Bacterium humidity is 45%~55%, and the sterilization functions time is 3h~4h, and disinfection intensity is in 1500mg/hL~2000mg/hL.
The process of chiseling and carving includes being beaten the allogeneic cartilage by laser equipment as a preferred technical solution,
Hole.
Laser equipment is 0.02mm- to the bore dia that the allogeneic cartilage punches as a preferred technical solution,
0.1mm；Hole density is 3000-200000/cm2。
The utility model has an advantageous effect in that：Pass through the design of bridge of the nose section so that prosthese is in close contact with nasal bone, no
It can displacement or abrasion；Body fluid can be allowed to flow into hole by the hole on the bridge of the nose makes tissue grow into hole, allows nose
It is connected with ose implant, prevents ose implant movement, fall off, fester, prevent the feeling of pain of postoperative patient.
Description of the drawings
It, below will be to implementing in order to illustrate more clearly of the utility model embodiment or technical solution in the prior art
Scheme or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, the accompanying drawings in the following description
Only some embodiments of the utility model are not making the creative labor for those of ordinary skill in the art
Under the premise of property, other drawings may also be obtained based on these drawings.
Fig. 1 is the utility model：A kind of structural schematic diagram for nose shaping filling allogeneic decalcification bone；
Fig. 2 is the utility model：A kind of vertical view of structure for nose shaping filling allogeneic decalcification bone；
Fig. 3 is the utility model：A kind of preparation method of structure for nose shaping filling allogeneic decalcification bone
Flow diagram.
Specific implementation mode
In order to make the technical means, creative features, achievement of purpose, and effectiveness of the utility model be easy to understand, under
Face combines and is specifically illustrating, and the utility model is expanded on further.
Referring to Fig.1 shown in -2, a kind of structure for nose shaping filling allogeneic decalcification bone, including by allogeneic
The nasal bone matrix 100 that decalcification bone is made, nasal bone matrix 100 include nose 1, nose pillar 2, the bridge of the nose 3, and the bridge of the nose 3 passes through nose 1
Connect nose pillar 2；There is narrowed changeover portion 4, the width of the changeover portion 4 to be less than the bridge of the nose 3 between the bridge of the nose 3 and nose 1
Width, changeover portion 4 can so that nose it is more moulding；The lower part of the bridge of the nose 3 is by two shapes that are in the shape of the letter V, 12 groups of bridge of the nose section arranged in a crossed manner
At, and the nasal bone of human body is located between two bridge of the nose sections 12, to ensure that prosthese will not displacement and abrasion.
The surface of the bridge of the nose 3 of the utility model is densely covered with numerous holes 11, can by hole 11 so that prosthese has elasticity
To stretch, can be very good fitting nose, hole 11 can allow body fluid to flow into and hole 11 and grow tissue, allow nose with
Ose implant is connected, and prevents ose implant movement, falls off, festers, prevents the feeling of pain of postoperative patient.Preferably, hole 11 is
Through-hole or non through hole.
The hole 11 of the utility model is non through hole, and the bottom of hole 11 is plane or arc surface.Hole 11, which can be used, to swash
What light typed it out, laser equipment punched hole, hole periphery is mellow and full, and bottom is one smooth, impulse- free robustness.
The surface for being arranged in the bridge of the nose 3 or bridge of the nose section 12 of the rule of hole 11 of the utility model, hole 11 and hole 11 it
Between spacing it is identical, it is whole very beautiful.The bore dia of hole 11 is 0.02mm-0.1mm；Hole density be 3000-200000/
cm2。
With reference to shown in Fig. 3, the utility model also proposed a kind of knot for nose shaping filling allogeneic decalcification bone
The preparation method of structure, includes the following steps：
A bone) is taken, obtains allogeneic cartilage in an aseptic environment, wherein the allogeneic cartilage is non-self rib
Bone, non-Auricular cartilage.
B it) handles, the allogeneic cartilage of acquirement is subjected to degreasing, decalcification, de- albumen and sterilization treatment successively；
C it) chisels and carves, treated allogeneic cartilage is chiseled and carved into the shape of needs, you can.
Concrete processing procedure in the step B of the utility model includes：
(1) allogeneic cartilage is immersed in chloroform and methyl alcohol mixed liquor body 6-24 hours；Wherein：The chloroform and
The volume ratio of chloroform and methanol in methyl alcohol mixed liquor is 1：1；
(2) by above-mentioned steps (1), treated that the allogeneic cartilage is added in hydrochloric acid solution, and it is small persistently to stir 8-12
When；A concentration of 0.5-0.6mol/L of the hydrochloric acid solution；
(3) by above-mentioned steps (2), treated that the allogeneic cartilage immerses TritonX-100 and ammonium hydroxide mixed solution
Middle effect 2-72 hours；The volumn concentration of the TritonX-100 and the TritonX-100 in ammonium hydroxide mixed solution is
The mass percentage of 0.1%-2%, ammonia are 0.3%；
(4) by above-mentioned steps (3) treated allogeneic cartilage freeze-drying, sterilization treatment；Wherein, described cold
Be lyophilized it is dry refer to by the allogeneic cartilage be put into -72 DEG C~-80 DEG C of freeze dryer it is freeze-dried for 24 hours~48h；It is described to go out
Bacterium processing refers to that will be put into ethylene oxide sterilizer to sterilize after allogeneic cartilage plastic bag packaging seal, epoxy second
In 480mg/L~520mg/L, sterilising temp is controlled at 38 DEG C~42 DEG C for the mass concentration control of alkane, and sterilizing humidity is 45%~
55%, the sterilization functions time is 3h~4h, and disinfection intensity is in 1500mg/hL~2000mg/hL.
The process of chiseling and carving in the step C of the utility model includes being beaten the allogeneic cartilage by laser equipment
Hole, wherein bore dia 0.02mm-0.1mm；Hole density is 3000-200000/cm2。
Embodiment 1
1, non-self rib cartilage is obtained in an aseptic environment；It is preferred that the 11st section or the 12nd section rib cage are taken, with distillation
Water is cleaned up and is impregnated；
2, the allogeneic cartilage is immersed 24 hours in chloroform and methyl alcohol mixed liquor body and carries out degreasing；Wherein：It is described
The volume ratio of chloroform and methanol in chloroform and methyl alcohol mixed liquor is 1：1, it is cleaned with distilled water after taking-up；
3, the allogeneic cartilage after degreasing is immersed in the hydrochloric acid solution of a concentration of 0.5mol/L, and it is small to continue stirring 12
Shi Jinhang decalcifications, are cleaned after taking-up with distilled water；
4, the allogeneic cartilage after decalcification is immersed in TritonX-100 and ammonium hydroxide mixed solution to act on 72 hours and is carried out
De- albumen；Wherein, the volumn concentration of the TritonX-100 and the TritonX-100 in ammonium hydroxide mixed solution are
1.5%, the mass percentage of ammonia is 0.3%, is cleaned with distilled water after taking-up；
5, by the allogeneic cartilage after de- albumen be placed in -80 DEG C of freeze dryer it is freeze-dried for 24 hours after, with polybag packet
Sterilizing in ethylene oxide sterilizer is put into after dress sealing, the mass concentration of ethylene oxide is controlled in 500mg/L, sterilising temp 38
DEG C, sterilizing humidity is 45%, and the sterilization functions time is 3h, and disinfection intensity is in 1500mg/hL.
6, treated allogeneic cartilage is chiseled and carved into the shape of needs, you can implantation.It is of the same race different in order to ensure
The stabilization of body cartilage, the allogeneic cartilage punch its surface by laser equipment, wherein bore dia 0.05mm；Hole
Density is 10000/cm2。
Embodiment 2
1, non-Auricular cartilage is obtained in an aseptic environment；It is clean wash with distilled water and impregnate；
2, the allogeneic cartilage is immersed 24 hours in chloroform and methyl alcohol mixed liquor body and carries out degreasing；Wherein：It is described
The volume ratio of chloroform and methanol in chloroform and methyl alcohol mixed liquor is 1：1, it is cleaned with distilled water after taking-up；
3, the allogeneic cartilage after degreasing is immersed in the hydrochloric acid solution of a concentration of 0.6mol/L, and it is small to continue stirring 12
Shi Jinhang decalcifications, are cleaned after taking-up with distilled water；
4, the allogeneic cartilage after decalcification is immersed in TritonX-100 and ammonium hydroxide mixed solution to act on 72 hours and is carried out
De- albumen；Wherein, the volumn concentration of the TritonX-100 and the TritonX-100 in ammonium hydroxide mixed solution are 1%,
The mass percentage of ammonia is 0.3%, is cleaned with distilled water after taking-up；
5, by the allogeneic cartilage after de- albumen be placed in -80 DEG C of freeze dryer it is freeze-dried for 24 hours after, with polybag packet
Sterilizing in ethylene oxide sterilizer is put into after dress sealing, the mass concentration of ethylene oxide is controlled in 500mg/L, sterilising temp 40
DEG C, sterilizing humidity is 45%, and the sterilization functions time is 3h, and disinfection intensity is in 2000mg/hL.
6, treated allogeneic cartilage is chiseled and carved into the shape of needs, you can implantation.It is of the same race different in order to ensure
The stabilization of body cartilage, the allogeneic cartilage punch its surface by laser equipment, wherein bore dia 0.05mm；Hole
Density is 15000/cm2。
Embodiment 3
1, non-self rib cartilage is obtained in an aseptic environment；It is preferred that the 11st section or the 12nd section rib cage are taken, with distillation
Water is cleaned up and is impregnated；
2, the allogeneic cartilage is immersed 24 hours in chloroform and methyl alcohol mixed liquor body and carries out degreasing；Wherein：It is described
The volume ratio of chloroform and methanol in chloroform and methyl alcohol mixed liquor is 1：1, it is cleaned with distilled water after taking-up；
3, the allogeneic cartilage after degreasing is immersed in the hydrochloric acid solution of a concentration of 0.6mol/L, and it is small to continue stirring 12
Shi Jinhang decalcifications, are cleaned after taking-up with distilled water；
4, the allogeneic cartilage after decalcification is immersed in TritonX-100 and ammonium hydroxide mixed solution to act on 72 hours and is carried out
De- albumen；Wherein, the volumn concentration of the TritonX-100 and the TritonX-100 in ammonium hydroxide mixed solution are
0.5%, the mass percentage of ammonia is 0.3%, is cleaned with distilled water after taking-up；
5, by the allogeneic cartilage after de- albumen be placed in -80 DEG C of freeze dryer it is freeze-dried for 24 hours after, with polybag packet
Sterilizing in ethylene oxide sterilizer is put into after dress sealing, the mass concentration of ethylene oxide is controlled in 500mg/L, sterilising temp 38
DEG C, sterilizing humidity is 45%, and the sterilization functions time is 3h, and disinfection intensity is in 1500mg/hL.
6, treated allogeneic cartilage is chiseled and carved into the shape of needs, you can implantation.It is of the same race different in order to ensure
The stabilization of body cartilage, the allogeneic cartilage punch its surface by laser equipment, wherein bore dia 0.08mm；Hole
Density is 8000/cm2。
Comparing result
Respectively in accordance with the above-mentioned embodiment 1,2,3 preparation method makes nasal bone prosthese, and is implanted into corresponding human body
Into line trace and observation, statistical data is shown in Table lattice 1.
Table 1
Result surface prosthesis implantation effect is good, no rejection, and healing is good.
Since the material of the utility model uses allogeneic decalcification cartilage, no rejection, and hole is equipped on the surface of cartilage
Hole, body fluid can be allowed to flow into hole by hole makes tissue grow into hole, allows nose to be connected with ose implant, prevent nose
Prosthese is mobile, falls off, festers, and prevents the feeling of pain of postoperative patient.
The advantages of basic principles and main features and the utility model of the utility model have been shown and described above.One's own profession
The technical staff of industry is it should be appreciated that the present utility model is not limited to the above embodiments, described in above embodiments and description
Only illustrate the principles of the present invention, on the premise of not departing from the spirit and scope of the utility model, the utility model is also
It will have various changes and improvements, these various changes and improvements fall within the scope of the claimed invention.The utility model
Claimed range is defined by the appending claims and its equivalent thereof.
Claims (1)
1. a kind of structure for nose shaping filling allogeneic decalcification bone, which is characterized in that including by allogeneic decalcification
The nasal bone matrix that bone is made, the nasal bone matrix include nose, nose pillar, the bridge of the nose, and the bridge of the nose connects nose by nose
Pillar；There is narrowed changeover portion, the width of the changeover portion to be less than the width of the bridge of the nose between the bridge of the nose and nose；
The lower part of the bridge of the nose is made of two shapes that are in the shape of the letter V bridge of the nose section arranged in a crossed manner, and the nasal bone of human body is located at two institutes
It states between bridge of the nose section；
The surface of the bridge of the nose is densely covered with numerous holes；
Described hole is non through hole, and the bottom of described hole is plane or arc surface；
The surface for being arranged in the bridge of the nose of described hole rule, the spacing between described hole and hole are identical；
The density of a diameter of 0.02mm-0.1mm of described hole, hole are 3000-200000/cm2。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621342369.1U CN207734389U (en) | 2016-12-08 | 2016-12-08 | A kind of structure for nose shaping filling allogeneic decalcification bone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621342369.1U CN207734389U (en) | 2016-12-08 | 2016-12-08 | A kind of structure for nose shaping filling allogeneic decalcification bone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207734389U true CN207734389U (en) | 2018-08-17 |
Family
ID=63113760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621342369.1U Active CN207734389U (en) | 2016-12-08 | 2016-12-08 | A kind of structure for nose shaping filling allogeneic decalcification bone |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207734389U (en) |
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2016
- 2016-12-08 CN CN201621342369.1U patent/CN207734389U/en active Active
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