CN207570204U - For the device of glass-chip dehydration - Google Patents

For the device of glass-chip dehydration Download PDF

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Publication number
CN207570204U
CN207570204U CN201721631416.9U CN201721631416U CN207570204U CN 207570204 U CN207570204 U CN 207570204U CN 201721631416 U CN201721631416 U CN 201721631416U CN 207570204 U CN207570204 U CN 207570204U
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China
Prior art keywords
chip
box cover
glass
box body
box
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CN201721631416.9U
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Chinese (zh)
Inventor
吴晶晶
刘灵辉
杨思贤
郭翠滨
刘强
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Guangzhou Bo Chong Biotechnology Co Ltd
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Guangzhou Bo Chong Biotechnology Co Ltd
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Abstract

The utility model discloses a kind of devices for glass-chip dehydration, including glass-chip box body, the first box cover, blotting paper, filling block and the second box cover, second box cover is equipped with upward groove, blotting paper is equipped in groove, first box cover is equipped with window, and blotting paper is close to window, and box body is matched with the first box cover, gap is equipped between first box cover and the second box cover, filling block is set in gap.The chip dehydration device of the application washes dry instrument compared to chip centrifuge tube, dedicated chip, can once centrifuge 50, flux significantly improves;In addition, since glass-chip box space is big, close-packed arrays are not needed between chip, moisture is more advantageous to and is detached from chip surface, reaching reduces background noise purpose;Glass-chip box body chips use traverse, and the moisture on chip gets rid of the width (i.e. 245~254mm) that the distance that needs flow through is oblong chips, this distance is shorter than the distance of water flow on the chip placed vertically, can effectively reduce noise.

Description

For the device of glass-chip dehydration
Technical field
The utility model is related to biochip dehydration technique field, especially a kind of devices for glass-chip dehydration.
Background technology
Protein chip, to ensure the low background of chip, needs to pass through cleaning before immune response, particularly last colour developing Sample and reagent extra on chip are removed, but after cleaning, it is also necessary to remaining moisture on chip is removed, to ensure chip Background homogeneity reduces noise, avoids influencing testing result.
The prior art is got rid of liquid or is done with wind using centrifugation technique rotation.Since air drying process leaves irregular washmarking Cause background inhomogenous, influence testing result, in addition, it is a slow process to air-dry, albumen may be caused impacted, it is also possible to It can lead to fluorescent quenching and then influence signal scheme, so that final detection result can be affected, so with wind dry doubling not It is common.Research staff often gets rid of liquid with centrifugal device rotation, i.e., dries the water on slide by way of centrifugation.
At present, on the market there are two types of the common devices for slide centrifugation, one kind is with chip centrifuge tube, chip centrifugation Pipe borrows the centrifuge tube of present 50mL specifications, and two opposite grooves of 180 degree are designed in centrifuge tube, and size is just inserted Enter a glass matrix chip (750~786mm × 245~254mm × 11-16mm).Moisture during centrifugation on chip is from slide On be thrown to chip centrifugation bottom of the tube.Can borrow in this way the centrifuge tube of existing 50mL specifications centrifugal device (centrifugal rotor and Centrifuge), it does not need to additionally be designed.
Chip centrifuge tube has 3 shortcomings:(1) it is the centrifuge tube of a 50mL specification since centrifuge tube specification limits A piece of chip can only be once packed into, flux is not high, and the number of chips centrifuged every time is limited;
(2) chip is to place vertically, and the moisture content on chip will get rid of, and needs the length that the distance flowed through is oblong chips Spend 750~786mm, this, thus may be dry in midway apart from long, forms higher background, cause when detecting compared with Big noise;
(3) heart is separated water into bottom of the tube is centrifuged by centrifugation, when taking out chip, moisture is easily contacted again chip, Drying is caused to be not thorough, influences chip results.
Second for slide centrifugation device be centrifugal device design exclusively for chip, including special centrifuge with Mating rotor, support chip place equipment.Its shortcoming includes:
(1) because special design, price is costly;
(2) although higher than the flux of chip centrifuge tube, flux is still not high enough, and such as brilliant core SlideWasher chips are washed Dry instrument is once only capable of 8 sheet glass chips of centrifugation;
(3) chip is placed using vertical, and the moisture content on chip will get rid of, and it is oblong chips to need the distance flowed through 750~786mm of length, this, thus may be dry in midway apart from long, forms higher background, causes when detecting Larger noise.
Utility model content
It, can be fast the purpose of the utility model is to overcome one kind is provided in place of above-mentioned the deficiencies in the prior art based on this Speed, the device for thoroughly sloughing moisture on chip are dehydrated glass-chip using the device, and the advantage for having flux high takes off Glass-chip noise after water is extremely low, even without noise.
To achieve the above object, the technical solution that the utility model is taken is:For glass-chip dehydration device, including Glass-chip box body, the first box cover, blotting paper, filling block and the second box cover, second box cover is equipped with upward groove, described Be equipped with blotting paper in groove, first box cover is equipped with window, and the blotting paper is close to the window, the box body and First box cover matches, and gap is equipped between first box cover and second box cover, and the filling block is set on described In gap.Box body is located at the top of the first box cover as a result, and box body is interior equipped with multiple glass-chips, on the glass-chip after cleaning It is remaining it is water stain in centrifugal process to the first box cover flow, then absorbed by blotting paper, quickly can thoroughly slough glass Moisture on chip;Filling block can ensure that box body will not be moved with the first box cover in the second box cover, and glass-chip is avoided to exist Fragmentation in centrifugal process.
Preferably, the blotting paper is dry filter paper.
Preferably, the card slot of at least 15 glass-chips is equipped in the glass-chip box body.As a result, relative to existing Chip centrifugal device, the centrifugation flux of the device of the application significantly improve, and can significantly improve the dehydration efficiency of glass-chip;Root According to needs, the quantity of the card slot of glass-chip can be adjusted.Wherein, 25 glass-chips are equipped in more preferable glass-chip box body Card slot.
Preferably, the filling block is silica gel block.Silica gel block has certain elasticity as a result, using the device of the application Glass-chip is dehydrated, when centrifugal device breaks down, flexible silica gel block can play the role of buffering collision of closed, keep away Exempt from glass-chip fragmentation.
Preferably, the overhead height of the filling block is identical with the bottom level of the box body.As a result, when the dress of the application It puts when being centrifuged in ELISA Plate rotor, since the overhead height of filling block is identical with the bottom level of the box body, in rotor Middle distribution of weight is uniform, also opposite to the operating on centrifugal force of glass-chip to mitigate, can be to avoid glass-chip due to unbalance stress And fragmentation.
Preferably, the distance of 1~8mm is equipped between the edge of the edge of the window and first box cover.It should say Bright, when distance is less than 1mm between the edge of the edge of window and first box cover, glass-chip is possible to centrifuging In the process, deviate from from window;And when distance is more than 8mm between the edge of the edge of window and first box cover, part is remote The moisture that chip from window is taken off may remain in chip bottom, it is impossible to it is absorbed immediately by blotting paper, it is larger so as to generate Noise.
Preferably, the distance of 4mm is equipped between the edge of the edge of the window and first box cover.Work as window as a result, Mouthful edge and first box cover edge between equipped with 4mm apart from when, glass-chip will not be in centrifugal process from window Mouth abjection, blotting paper can also will be far from the moisture absorption that the chip of window is taken off immediately.
It is highly preferred that the height of the box body is 248~261mm.The chip in glass-chip box body is traverse as a result, , then moisture generally moves in centrifugal process on the short side direction of rectangular chip, and the width of short side is 245~ 254mm when the height of box body is 248~261mm, can accommodate the chip of traverse, meanwhile, it can be to avoid leaving larger sky Between so that chip shakes in box body.
In conclusion the beneficial effects of the utility model are:
(1) the chip dehydration device of the application washes dry instrument compared to chip centrifuge tube, dedicated chip, can once centrifuge 50 Piece, flux significantly improve;In addition, since glass-chip box space is big, close-packed arrays are not needed between chip, are more advantageous to water Divide and be detached from chip surface, reaching reduces background noise purpose;
(2) the box body chips of the application use traverse, and it is rectangular that the moisture on chip, which gets rid of the distance that needs flow through, The width (i.e. 245~254mm) of shape chip, this distance are shorter than the distance of water flow on the chip placed vertically, can effectively drop Low noise.
Description of the drawings
Fig. 1 is the sectional view of the embodiment one of the utility model;
Fig. 2 is the explosive view of the embodiment one of the utility model;
Wherein, 1, glass-chip box body, the 2, first box cover, 3, dry filter paper, 4, silica gel block, the 5, second box cover, 6, groove, 7th, window, 8, gap, 9, glass-chip.
Specific embodiment
To better illustrate the purpose of this utility model, technical solution and advantage, below in conjunction with attached drawing and specific implementation The utility model is described in further detail for example.
Embodiment 1
As illustrated in fig. 1 and 2, a kind of embodiment of the device for glass-chip dehydration of the application, including glass-chip Box body 1, the first box cover 2, dry filter paper 3,4 and second box cover 5 of silica gel block, the second box cover 5 is equipped with upward groove 6, in groove 6 Dry filter paper 3 is equipped with, the first box cover 2 is equipped with window 7, and dry filter paper 3 is close to window 7, box body 1 and 2 phase of the first box cover Cooperation, is equipped with gap 8 between the first box cover 2 and the second box cover 5, silica gel block 4 is set in gap 8;
Wherein, the card slot of 25 glass-chips 9 is equipped in glass-chip box body 1;The overhead height of silica gel block 4 and box body 1 Bottom level it is identical;The distance of 4mm is equipped between the edge of the edge of window 7 and the first box cover 2;The height of box body 1 is 248 ~261mm.
The device of the present embodiment may be used following method and obtain:By among glass core film magazine (specification 25) box cover with cutting Cutter cuts empty window, using microwell plate plate lid as the second box cover 5, glass-chip is put into glass-chip box body, is then covered Upper first box cover 2, for the first box cover under, glass core film magazine is placed on the microwell plate plate lid for being equipped with dry filter paper upper by box body 1 Interior, upward, the vacant place of microwell plate plate lid inserts the gap in microwell plate plate lid to microwell plate plate lid with sizeable silica gel block 4 It is interior.Combination of the above is put into the dehydration device of glass-chip in ELISA Plate rotor, it may be convenient to be realized disposably to multiple glass Glass chip centrifuges simultaneously.The moisture on chip is thrown in the following, being absorbed (filter paper is replaceable) by dry filter paper as a result,.
The utility model raw material are easily obtained, cheap, glass core film magazine therein, microwell plate plate lid, silica gel block All it is general or common consumptive material.
Finally, it should be noted that above example is only to illustrate the technical solution of the utility model rather than to this reality With the limitation of novel protected range, although being explained in detail with reference to preferred embodiment to the utility model, this field it is common It will be appreciated by the skilled person that the technical solution of the utility model can be modified or replaced equivalently, without departing from this reality With the spirit and scope of new technique scheme.

Claims (9)

1. for the device of glass-chip dehydration, which is characterized in that including glass-chip box body, the first box cover, blotting paper, filling Block and the second box cover, second box cover are equipped with upward groove, are equipped with blotting paper in the groove, on first box cover Equipped with window, the blotting paper is close to the window, and the box body is matched with first box cover, first box cover with Gap is equipped between second box cover, the filling block is set in the gap.
2. the apparatus according to claim 1, which is characterized in that the blotting paper is dry filter paper.
3. the apparatus according to claim 1, which is characterized in that at least 15 glass cores are equipped in the glass-chip box body The card slot of piece.
4. device according to claim 3, which is characterized in that 25 glass-chips are equipped in the glass-chip box body Card slot.
5. the apparatus according to claim 1, which is characterized in that the filling block is silica gel block.
6. device according to claim 1 or 5, which is characterized in that the overhead height of the filling block and the box body Bottom level is identical.
7. the apparatus according to claim 1, which is characterized in that the edge of the edge of the window and first box cover it Between be equipped with 1~8mm distance.
8. device according to claim 7, which is characterized in that the edge of the edge of the window and first box cover it Between be equipped with 4mm distance.
9. device according to claim 8, which is characterized in that the height of the box body is 248~261mm.
CN201721631416.9U 2017-11-29 2017-11-29 For the device of glass-chip dehydration Active CN207570204U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721631416.9U CN207570204U (en) 2017-11-29 2017-11-29 For the device of glass-chip dehydration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721631416.9U CN207570204U (en) 2017-11-29 2017-11-29 For the device of glass-chip dehydration

Publications (1)

Publication Number Publication Date
CN207570204U true CN207570204U (en) 2018-07-03

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201721631416.9U Active CN207570204U (en) 2017-11-29 2017-11-29 For the device of glass-chip dehydration

Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109140927A (en) * 2018-08-23 2019-01-04 重庆市嘉凌新科技有限公司 Chip drying mechanism

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109140927A (en) * 2018-08-23 2019-01-04 重庆市嘉凌新科技有限公司 Chip drying mechanism

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