CN207336302U - A kind of cell state detection device - Google Patents

A kind of cell state detection device Download PDF

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Publication number
CN207336302U
CN207336302U CN201721339054.6U CN201721339054U CN207336302U CN 207336302 U CN207336302 U CN 207336302U CN 201721339054 U CN201721339054 U CN 201721339054U CN 207336302 U CN207336302 U CN 207336302U
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cell
detection instrument
filter column
checking device
sample delivery
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CN201721339054.6U
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Chinese (zh)
Inventor
淦志兵
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Shanghai Root Biotechnology Co Ltd
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Shanghai Root Biotechnology Co Ltd
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Abstract

The utility model discloses a kind of cell state detection device, including the cell detection instrument that can detect cell state and fast checking device, fast checking device is arranged on cell detection instrument side, and sample delivery channel is connected by isocon with cell detection instrument, sample delivery channel is disposed with spray tube and Filter column from top to bottom at the top of connection cell detection instrument and fast checking device, Filter column is tilted and is fixed in sample delivery channel, and filtering column bottom sludge outlet passes through the slagging channel outside isocon connection;Fast checking device includes long defeated passage and chromatographic film, and chromatographic film both ends are respectively fixedly connected with the port of long defeated passage, long defeated channel output end connection header tank;Long defeated passage outer bottom is provided with colorimetric card, and colorimetric card vertical direction is provided with observation window;Use two kinds of different inspection apparatus for same cell stoste, there is provided the experimental data that can be contrasted, can detect laboratory apparatus whether can normal use, more accurately obtain experimental result.

Description

A kind of cell state detection device
Technical field
Cell detection equipment technical field is the utility model is related to, is specially a kind of cell state detection device.
Background technology
Current flow cytometry detection device, as middle and high end blood analyser and stream type cell analyzer all use streaming Counting principle is counted and classified to cell or particle.Sample to be tested cell or particle is wherein set to pass through detection zone one by one Sheath stream (fluid focus) technology be flow cytometry core, since the needs of measuring speed are, it is necessary to ensure when limited The interior quick sample flow for establishing stabilization, while can also fast and effective cleaning be carried out to related fluid circuit unit.
, can not be directly perceived but existing cell detection equipment, which is mainly detected detection sample, needs the regular hour Check as a result, and check result do not contrast reference substance.
The content of the invention
The technical problems to be solved in the utility model is to overcome existing detection device to be mainly detected detection sample to need Want the regular hour, can not intuitively check as a result, and result the defects of not contrasting reference substance for checking, there is provided it is a kind of Cell state detection device, so as to solve the above problems.
In order to solve the above-mentioned technical problem, the utility model provides following technical solution:
A kind of cell state detection device of the utility model, including the cell detection instrument of detectable cell state and fast inspection fill Put, fast checking device is arranged on cell detection instrument side, and connects sample delivery channel, sample by isocon with cell detection instrument Transfer passage is disposed with spray tube and Filter column from top to bottom at the top of connection cell detection instrument and fast checking device, filters Column is tilted and is fixed in sample delivery channel, and filtering column bottom sludge outlet passes through the slagging channel outside isocon connection; Fast checking device includes long defeated passage and chromatographic film, and chromatographic film both ends are respectively fixedly connected with the port of long defeated passage, and long defeated passage is defeated Outlet connects header tank;Long defeated passage outer bottom is provided with colorimetric card, and colorimetric card vertical direction is provided with observation window.
As a kind of optimal technical scheme of the utility model, spray tube input terminal connection micro pump.
As a kind of optimal technical scheme of the utility model, Filter column includes filter core and rotation axis, and rotation axis is fixed on At the center of Filter column, it is fixedly connected at the top of rotation axis with inducer, inducer bottom is provided with filter core, and filter core is fixed on filtering On the madial wall of column, brush, brush key connection rotation axis are flexibly connected on the inside of filter core.
As a kind of optimal technical scheme of the utility model, long defeated passage is pacified made of transparent material at the top of it The observation window of dress is made of double glazing, and observation window inner layer glass piece is enlarging lens.
The beneficial effect that the utility model is reached is:
1st, the method for cell detection provided by the utility model, can carry out certainly detecting instrument while detection process It is lower and on cleaning, substantially increase the work efficiency of whole system, and this cleaning way be by from gravity to detection Instrument is cleaned, and cleaning way effect is fine.
2nd, the Filter column used during instrument use has the function of automatic adjustment, according to sample in sample delivery channel The size of product flow velocity determines cleaning speed, and using the power of fluid, can not only replace electric power source, reach the saving energy Effect, and need not regular maintenance, the use cost greatly reduced;Filter column is applied not only to the cleaning of equipment at the same time, to thin Born of the same parents' stoste is also filtered, and can greatly reduce impurity to the interference element in experiment by the waste material discharge in cell stoste outside.
3rd, two kinds of different inspection apparatus are used for same cell stoste, there is provided the experimental data that can be contrasted, can examine Survey laboratory apparatus whether can normal use, more accurately obtain experimental result.
Brief description of the drawings
Attached drawing is used to provide a further understanding of the present invention, and a part for constitution instruction, with this practicality New embodiment is used to explain the utility model together, does not form the limitation to the utility model.
In the accompanying drawings:
Fig. 1 is the utility model overlooking the structure diagram;
Fig. 2 is the utility model Filter column internal structure schematic diagram;
Figure label:1st, sample delivery channel;2nd, isocon;3rd, spray tube;4th, Filter column;401st, inducer;402nd, revolve Shaft;403rd, filter core;404th, brush;5th, slagging channel;6th, cell detection instrument;7th, fast checking device;8th, long defeated passage;9th, chromatograph Film;10th, header tank;11st, colorimetric card;12nd, observation window.
Embodiment
The preferred embodiment of the utility model is illustrated below in conjunction with attached drawing, it will be appreciated that described herein excellent Select embodiment to be only used for describing and explaining the present invention, be not used to limit the utility model.
, it is necessary to explanation in the description of the utility model, the instruction such as term " vertical ", " on ", " under ", " level " Orientation or position relationship are based on orientation shown in the drawings or position relationship, are for only for ease of description the utility model and simplification Description, rather than the device or element of instruction or hint meaning must have specific orientation, with specific azimuth configuration and behaviour Make, therefore it is not intended that limitation to the utility model.
In the description of the utility model, it is also necessary to which explanation, unless otherwise clearly defined and limited, term " are set Put ", " installation ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, Or it is integrally connected;Can mechanically connect or be electrically connected;It can be directly connected, intermediary can also be passed through It is indirectly connected, can is the connection inside two elements.For the ordinary skill in the art, can be according to specific feelings Condition understands concrete meaning of the above-mentioned term in the utility model.
Embodiment:As shown in Figs. 1-2, the utility model provides a kind of cell state detection device, including detectable cell The cell detection instrument 6 and fast checking device 7 of state, fast checking device 7 are arranged on 6 side of cell detection instrument, and logical with cell detection instrument 6 Cross isocon 2 connect sample delivery channel 1, sample delivery channel 1 connection cell detection instrument 6 and fast checking device 7 top from Top to bottm is disposed with spray tube 3 and Filter column 4,3 input terminal of spray tube connection micro pump, and Filter column 4 is tilted and is fixed on In sample delivery channel 1,4 bottom sludge outlet of Filter column connects the slagging channel 5 of outside by isocon 2;Fast checking device 7 Including the defeated passage 8 of length and chromatographic film 9,9 both ends of chromatographic film are respectively fixedly connected with the port of long defeated passage 8, long defeated 8 output terminal of passage Connect header tank 10;Long defeated 8 outer bottom of passage is provided with colorimetric card 11, and 11 vertical direction of colorimetric card is provided with observation window 12.
Filter column 4 includes filter core 403 and rotation axis 402, and rotation axis 402 is fixed at the center of Filter column 4, rotation axis 402 tops are fixedly connected with inducer 401, and 401 bottom of inducer is provided with filter core 403, and filter core 403 is fixed on Filter column 4 On madial wall, the inner side of filter core 403 is flexibly connected brush 404,404 key connection rotation axis 402 of brush.Fluid is flowed into by water inlet In Filter column 4, the inducer 401 inside Filter column 4 is promoted to rotate using the kinetic energy of fluid motion, inducer 401 drives rotation Axis 402 rotates, and drives the brush 404 being fixed in rotation axis 402 to rotate by rotation axis 402, by brush 404 to filter core 403 are cleaned, and can reach the purpose of clear Filter column 4 at any time;Sewage after cleaning after precipitation hole sediment fraction by passing through Slagging channel 5 is discharged, and the fluid after filtering is flowed into cell detection instrument 6 and fast checking device 7 by sample delivery channel 1.
Long defeated passage 8 is made of transparent material, and the observation window 12 installed at the top of it is made of double glazing, observation window 12 inner layer glass pieces are enlarging lens.
Operation principle:The utility model inputs dilution of stock to sample delivery before pattern detection, by spray tube 3 Passage 1, cell detection instrument 6 and fast checking device 7 are cleaned;Solution after cleaning respectively by slagging channel 5, header tank 10 with And the output port discharge of cell detection instrument 6;
During subsequent pattern detection, 1 input terminal of sample delivery channel is connected in cell culture stoste, is extracted thin in stoste Born of the same parents are respectively enterd after Filter column 4 in cell detection instrument 6 and fast checking device 7, in cell detection instrument 6, treat that sample flow is stablized Afterwards, open light-source system and produce laser, while open photodetector, sample to be tested is detected;Cell sampling at the same time Stoste enters in fast checking device 7, detected sample by by the chromatographic film 9 that the inside of the defeated passage of length 8 is set chromatographic film 2 work Chromatography effect is carried out under, carries out a series of chemical reaction, and is carried out pair according to the colorimetric card 11 that defeated 8 bottom of passage of length is set Than testing staff can be observed by observation window 12 judges substantially component and relevant parameter;And cell inspection is contrasted after a certain time Survey in instrument 6 data drawn to be analyzed, to show that data are more accurate;
After pattern detection, sample delivery channel 1, cell are examined by more than 3 input dilution of stock of spray tube Survey instrument 6 and fast checking device 7 is cleaned;Solution after cleaning passes through slagging channel 5, header tank 10 and cell detection instrument respectively 6 output port discharge;Last spray tube 3 injected clear water into sample delivery channel 1 carries out cleaning experiment instrument, after drying again Use.
Finally it should be noted that:It these are only the preferred embodiment of the utility model, be not limited to this practicality It is new, although the utility model is described in detail with reference to the foregoing embodiments, for those skilled in the art, It can still modify the technical solution described in foregoing embodiments, or which part technical characteristic is carried out etc. With replacement.Where within the spirit and principles of the present invention, any modification, equivalent replacement, improvement and so on, should all include Within the scope of protection of the utility model.

Claims (4)

  1. A kind of 1. cell state detection device, it is characterised in that the cell detection instrument including can detect cell state(6)With fast inspection Device(7), fast checking device(7)It is arranged on cell detection instrument(6)Side, and with cell detection instrument(6)Pass through isocon(2)Connection Sample delivery channel(1), sample delivery channel(1)In connection cell detection instrument(6)With fast checking device(7)Top from top to bottom It is disposed with spray tube(3)And Filter column(4), Filter column(4)Inclination is fixed on sample delivery channel(1)It is interior, Filter column(4) Bottom sludge outlet passes through isocon(2)Slagging channel outside connection(5);Fast checking device(7)Including the defeated passage of length(8)With Chromatographic film(9), chromatographic film(9)Both ends are respectively fixedly connected with long defeated passage(8)Port, long defeated passage(8)Output terminal connection collection Water tank(10);Long defeated passage(8)Outer bottom is provided with colorimetric card(11), colorimetric card(11)Vertical direction is provided with observation window (12).
  2. A kind of 2. cell state detection device according to claim 1, it is characterised in that spray tube(3)Input terminal connects Micro pump.
  3. A kind of 3. cell state detection device according to claim 1, it is characterised in that Filter column(4)Including filter core (403)And rotation axis(402), rotation axis(402)It is fixed on Filter column(4)Center at, rotation axis(402)Top and inducer (401)It is fixedly connected, inducer(401)Bottom is provided with filter core(403), filter core(403)It is fixed on Filter column(4)Madial wall On, filter core(403)Inner side is flexibly connected brush(404), brush(404)Key connection rotation axis(402).
  4. A kind of 4. cell state detection device according to claim 1, it is characterised in that long defeated passage(8)For transparent material Made of material, the observation window installed at the top of it(12)It is made of double glazing, observation window(12)Inner layer glass piece is magnifying glass Piece.
CN201721339054.6U 2017-10-18 2017-10-18 A kind of cell state detection device Active CN207336302U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201721339054.6U CN207336302U (en) 2017-10-18 2017-10-18 A kind of cell state detection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201721339054.6U CN207336302U (en) 2017-10-18 2017-10-18 A kind of cell state detection device

Publications (1)

Publication Number Publication Date
CN207336302U true CN207336302U (en) 2018-05-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201721339054.6U Active CN207336302U (en) 2017-10-18 2017-10-18 A kind of cell state detection device

Country Status (1)

Country Link
CN (1) CN207336302U (en)

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