CN207248747U - The micro-fluidic record interpretoscope of self-absorption multichannel - Google Patents
The micro-fluidic record interpretoscope of self-absorption multichannel Download PDFInfo
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- CN207248747U CN207248747U CN201720975898.3U CN201720975898U CN207248747U CN 207248747 U CN207248747 U CN 207248747U CN 201720975898 U CN201720975898 U CN 201720975898U CN 207248747 U CN207248747 U CN 207248747U
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Abstract
The utility model discloses a kind of micro-fluidic record interpretoscope of self-absorption multichannel, including detection case, the positive facade of the detection case is hinged with operation console, the both sides of detection case are respectively arranged with microfluidic card socket and printing single outlet, two-dimensional code scanning mechanism, the print module for printing analysis information, the transmission system for X to driving microfluidic card movement, the testing agency being detected to microfluidic card, the displacement system for the movement of Y-direction driving testing agency are disposed with the detection case；The mobile route of the testing agency and the mobile route of microfluidic card interlock in cross, and the mobile route of testing agency is provided with least two testing agency's check bits, which is all located at the top of the microfluidic card mobile route.Beneficial effect：System hardware uses the hardware module identical with existing mobile phone more, and the research and development time is short, and R＆D costs are low, and manufacture cost is low, can carry out multinomial detection with a microfluidic card, reduce testing cost and detection time.
Description
Technical field
Field of fast detection is the utility model is related to, more particularly to a kind of micro-fluidic record interpretation of self-absorption multichannel
Instrument.
Background technology
With the breakthrough acquired by material science, micro-nano processing technology and microelectronics, micro-fluidic chip
Developed rapidly.Micro-fluidic chip (microfluidic chip) is also known as " laboratory on chip " (lab-on-a-
Chip), it is based on micro electro mechanical processing technology, is made on the materials such as silicon chip, glass or dimethyl silicone polymer (PDMS)
Make microchannel network so that controlled fluid flows in microchannel network, so as to fulfill the reaction in biological and chemical field, divides
From, detection etc. operation.
Micro-fluidic immune rapid test piece currently used for medicine field of fast detection is only provided with a sense channel, such as
Need to measure has the content of immunological cross-reaction or the larger different target component of interference, it is necessary to make between each other in same sample
With multiple and different micro-fluidic immune rapid test pieces, measure several times, so not only cause detection efficiency low, and cause to examine
Cost is surveyed to be substantially increased.
Because existing micro-fluidic immune rapid test piece only has a sense channel, do not go out also in the prior art
The interpretoscope that now multiple sense channels are detected.
Utility model content
To solve above technical problem, the utility model provides a kind of micro-fluidic record interpretoscope of self-absorption multichannel, energy
Once the micro-fluidic immune rapid test piece of more sense channels is detected, improves detection efficiency, reduces testing cost.
Technical solution is as follows：
A kind of micro-fluidic record interpretoscope of self-absorption multichannel, is provided with detection case, its key is：The detection case is just
Facade is hinged with operation console, and the both sides of detection case are respectively arranged with microfluidic card socket and print single outlet, in the detection case
It is disposed with two-dimensional code scanning mechanism, the print module for printing analysis information, the transmission for X to driving microfluidic card movement
System, the testing agency being detected to microfluidic card, the displacement system for the movement of Y-direction driving testing agency；
The mobile route of the testing agency and the mobile route of microfluidic card interlock in cross, the mobile road of testing agency
Footpath is provided with least two testing agency's check bits, which is all located at the microfluidic card mobile route
Top.
Above-mentioned microfluidic card has at least 2 sense channels, and every sense channel can carry out a kind of immune detection, described
Every sense channel corresponds to testing agency's check bit., can be to the inspection after testing agency is moved to testing agency's check bit
The corresponding sense channel of mechanism check bit is surveyed to be detected.
Two-dimensional code scanning mechanism, input/output module, processor can use identical with existing intelligent mobile phone system
Module and processor, not only reduce the system research and development time, have saved R＆D costs.It is also easy to integrate, realizes self-priming more logical
The portability processing of the micro-fluidic record interpretoscope in road, can not only meet the use of medical institutions, also meet smaller families, stupidly
The requirement that melon formula uses.
The print module is thermal printer, which is believed by the printing of 232 interfaces and the processor
Output terminal connection is ceased, the exit slot of thermal printer is communicated with the printing single outlet.
Printing function, is easy to record and the preservation of testing result.
The transmission system is provided with microfluidic card clamping device and moves forward and backward stepper motor, the microfluidic card clamping machine
Structure is communicated with the microfluidic card socket, and the microfluidic card clamping device, which coordinates, is provided with microfluidic card, described to move forward and backward
Driving stepper motor microfluidic card clamping device moves back and forth, and the processor controls the anteroposterior position walk by transmitting circuit
Stepper motor works.
Using said system, processor, which can control, to be moved forward and backward stepper motor microfluidic card is accurately transmitted to check bit
Put, make detection information more accurate.
Microfluidic card clamping device can fix microfluidic card in transmit process, avoid microfluidic card from deviateing mobile road
Footpath.
The microfluidic card includes core plate, and Quick Response Code is provided with core plate, and the core plate top surface is along the flow direction of liquid
Sample area, at least two label areas and the detection band identical with label area quantity, the label are equipped with successively
Area is connected by split channel with sample area respectively, and the detection band is connected by microchannel with corresponding label area respectively,
The detection takes is equipped with detection reaction zone and reaction reference area along the flow direction of liquid successively.
By the 2 D code information on collecting test card bottom plate with regard to corresponding detection parameters data can be obtained.Reduce control
The operand of device and operation time, detection time is shortened, be detected easy to controller.Also, same microfluidic card is just
Multinomial detection can be carried out, detection time has been saved, has improved detection efficiency.
The transmitting circuit includes operational amplifier U1 and operational amplifier U2, the in-phase input end of operational amplifier U1 with
The control signal output connection of processor, inverting input are connected through resistance R1 with power supply, and inverting input is also through resistance R2
Ground connection, the output terminal of operational amplifier U1 are connected through base stages of the resistance R3 respectively with triode D1 and triode D2, triode D1
Collector be connected with pulse power supply, move forward and backward the cathode of stepper motor described in emitter connection, move forward and backward stepping electricity
The anode of machine is connected with the collector of triode D2, the emitter ground connection of triode D2；
The inverting input of operational amplifier U2 and the control signal output of processor connect, and in-phase input end is through resistance
R4 is connected with power supply, and in-phase input end is also grounded through resistance R5, the output terminal of operational amplifier U2 through resistance R6 respectively with three poles
Pipe D3 is connected with the base stage of triode D4, and the collector of triode D3 is connected with pulse power supply, and emitter connection is described front and rear
The anode of displacement stepper motor, the cathode for moving forward and backward stepper motor are connected with the collector of triode D4, the hair of triode D4
Emitter grounding.
The part I/O interfaces of cell phone processor can be connected as control signal output with transmitting circuit, handset processes
Device is by controlling the i.e. controllable stepper motor that moves forward and backward of the level height of signal that the I/O interfaces of the part export to rotate forward and instead
Turn, the back-and-forth motion of driving stepper motor microfluidic card is moved forward and backward so as to control.
The testing agency is provided with fluorescent optical sensor and fluorescence excitation light source, institute's displacement system driving fluorescent optical sensor
Moved with fluorescence excitation light source, the fluorescence signal input terminal connection of the fluorescent optical sensor and processor, the processor passes through
Light source control module controls the intensity of the fluorescence excitation light source；
Institute's displacement system is provided with erecting bed and left and right displacement stepper motor, the fluorescent optical sensor and fluorescent exciting
Source is fixed on erecting bed, and the left and right displacement driving stepper motor erecting bed moves left and right, and the processor passes through stepping electricity
Machine controller controls the left and right displacement stepper motor work.
Using the above structure, the fluorescence information of fluorescent optical sensor energy collecting test card, and fluorescence information is converted into telecommunications
Number send processor to, processor handles electric signal, obtains detection data.
After the fluorescence information of the complete passage of fluorescent optical sensor scanning collection, processor control left and right displacement stepper motor
Erecting bed is moved to above next passage, the fluorescence information of next passage is then gathered, realizes the miniflow to multichannel
Control card is detected.
The input/output module is the letter of capacitance touch screen, the signal output part of the capacitance touch screen and the processor
Cease input/output terminal connection.
Using the above structure, using the input/output module identical with existing mobile phone, easy to research and development of products.It is described wireless
Communication module is provided with 4G communication modules and wifi communication modules.Processor is led to by wireless communication module and host computer
Letter.
Using the 4G communication module identical with smart mobile phone, wifi communication modules, save R＆D costs and product is provided
Quality.
The processor is also associated with GPS module, and processor obtains positional information, the GPS communication module by GPS module
It is connected with the positional information input terminal of the processor, positional information is sent to cloud by the processor by wireless communication module
Data center.
GPS module uses the locating module identical with existing smart mobile phone, and the position of instrument can be obtained by GPS module
Information, visits maintenance in the later stage easy to staff.
Beneficial effect：Using the micro-fluidic record interpretoscope of the self-absorption multichannel of the utility model, system hardware uses more
The hardware module identical with existing mobile phone, the research and development time is short, and R＆D costs are low, and manufacture cost is low, can use a microfluidic card
Multinomial detection is carried out, reduces testing cost and detection time.
Brief description of the drawings
Fig. 1 is the structure diagram of the utility model；
Fig. 2 is the internal structure schematic diagram of the utility model；
Fig. 3 is the circuit diagram of the transmitting circuit of the utility model；
Fig. 4 is the system block diagram of the utility model；
Fig. 5 is the structure diagram of the microfluidic card of the utility model.
Embodiment
With reference to embodiment and attached drawing, the utility model is described in further detail.
As shown in Figure 1, Figure 2, Figure 4 shows, the micro-fluidic record interpretoscope of a kind of self-absorption multichannel, is provided with detection case 1, the inspection
The positive facade of measuring tank 1 is hinged with operation console 2, and the both sides of detection case 1 are respectively arranged with microfluidic card socket 3 and printing single outlet 4,
Be disposed with the detection case 1 two-dimensional code scanning mechanism 5, for print analysis information print module, for X to driving miniflow
The mobile transmission system of control card, the testing agency being detected to microfluidic card, the displacement for the movement of Y-direction driving testing agency
System.
Be provided with the operation console 2 processor, GPS module, capacitance touch screen 14, the processor is at smart mobile phone
Manage device.
The processor prints testing result, the paper delivery of the thermal printer 6 by 232 interface driver thermal printers 6
Mouth is communicated with the printing single outlet 4.The information input/output terminal of the processor is connected with capacitance touch screen 14.Processor
Positional information input terminal is connected with GPS communication module, and the processor device is led to by 4G communication modules, bluetooth module and wifi
Believe module connection internet, data interaction is carried out with cloud data center.
The transmission system is provided with microfluidic card clamping device 7 and moves forward and backward stepper motor 8, microfluidic card clamping
Mechanism 7 is communicated with the microfluidic card socket 3, and the microfluidic card clamping device 7, which coordinates, is provided with microfluidic card 9, before described
Displacement stepper motor 8 drives microfluidic card clamping device 7 to move back and forth afterwards, the processor by transmitting circuit control it is described before
Displacement stepper motor 8 works afterwards.
The transmitting circuit includes operational amplifier U1 and operational amplifier U2, the in-phase input end of operational amplifier U1 with
The control signal output connection of processor, inverting input are connected through resistance R1 with power supply, and inverting input is also through resistance R2
Ground connection, the output terminal of operational amplifier U1 are connected through base stages of the resistance R3 respectively with triode D1 and triode D2, triode D1
Collector be connected with pulse power supply, move forward and backward the cathode of stepper motor 8 described in emitter connection, move forward and backward stepping electricity
The anode of machine 8 is connected with the collector of triode D2, the emitter ground connection of triode D2；
The inverting input of operational amplifier U2 and the control signal output of processor connect, and in-phase input end is through resistance
R4 is connected with power supply, and in-phase input end is also grounded through resistance R5, the output terminal of operational amplifier U2 through resistance R6 respectively with three poles
Pipe D3 is connected with the base stage of triode D4, and the collector of triode D3 is connected with pulse power supply, and emitter connection is described front and rear
The anode of displacement stepper motor 8, the cathode for moving forward and backward stepper motor 8 are connected with the collector of triode D4, triode D4's
Emitter is grounded.
The testing agency is provided with fluorescent optical sensor 10 and fluorescence excitation light source 11, and institute's displacement system driving fluorescence passes
Sensor 10 and fluorescence excitation light source 11 move, and the fluorescent optical sensor 10 is connected with the fluorescence information input terminal of processor, described
Processor controls the intensity of the fluorescence excitation light source 11 by light source control module；
Institute's displacement system is provided with erecting bed 12 and left and right displacement stepper motor 13, the fluorescent optical sensor 10 and fluorescence
Excitation source 11 is fixed on erecting bed 12, and the left and right displacement stepper motor 13 drives erecting bed 12 to move left and right, the place
Reason device controls the left and right displacement stepper motor 13 to work by controllor for step-by-step motor.
The mobile route of the testing agency and the mobile route of microfluidic card interlock in cross, the mobile road of testing agency
Footpath is provided with least two testing agency's check bits, which is all located at the microfluidic card mobile route
Top.
If shown in Fig. 5, the microfluidic card 9 includes core plate 9a, is provided with Quick Response Code on core plate 9a, core plate 9a top surfaces are suitable
The flow direction of liquid be equipped with successively sample area 9b, at least two label area 9c and with the label area 9c quantity phases
Same detection band 9d, the label area 9c is connected by split channel 9e with sample area 9b respectively, described to detect band 9d difference
Connected by microchannel 9f with corresponding label area 9c, it is described detection band 9d on along the flow direction of liquid successively equipped with examine
Survey reaction zone 9g and reaction reference area 9h.
Finally it should be noted that foregoing description is only the preferred embodiment of the utility model, the common skill of this area
Art personnel on the premise of without prejudice to the utility model aims and claim, can make under the enlightenment of the utility model
Expression, such conversion are each fallen within the scope of protection of the utility model as multiple types.
Claims (10)
1. a kind of micro-fluidic record interpretoscope of self-absorption multichannel, is provided with detection case (1), it is characterised in that：The detection case (1)
Positive facade be hinged with operation console (2), the both sides of detection case (1) are respectively arranged with microfluidic card socket (3) and printing single outlet
(4), be disposed with the detection case (1) two-dimensional code scanning mechanism (5), the print module for printing analysis information, for X to
The transmission system of microfluidic card movement is driven, the testing agency being detected to microfluidic card, drive testing agency's shifting for Y-direction
Dynamic displacement system；
The mobile route of the testing agency and the mobile route of microfluidic card interlock in cross, and the mobile route of testing agency is set
At least two testing agency's check bits are equipped with, which is all located at the upper of the microfluidic card mobile route
Side.
2. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 1, it is characterised in that：The operation console (2)
Inside be provided with wireless communication module and processor, which is smart mobile phone processor, the processor respectively with the detection
Mechanism, displacement system, print module, wireless communication module are connected with transmission system, and it is defeated that processor has also been bi-directionally connected input
Go out module, which is used for input instruction and display information.
3. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The transmission system is set
It is equipped with microfluidic card clamping device (7) and moves forward and backward stepper motor (8), the microfluidic card clamping device (7) and the miniflow
Control card plug (3) communicates, and the microfluidic card clamping device (7), which coordinates, is provided with microfluidic card (9), described to move forward and backward stepping
Motor (8) driving microfluidic card clamping device (7) move back and forth, the processor by transmitting circuit control described in move forward and backward
Stepper motor (8) works.
4. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 3, it is characterised in that：The microfluidic card
(9) be provided with core plate (9a), Quick Response Code be provided with core plate (9a), core plate (9a) top surface along the flow direction of liquid successively
Equipped with sample area (9b), at least two label areas (9c) and the detection band identical with label area (9c) quantity
(9d), the label area (9c) are connected by split channel (9e) with sample area (9b) respectively, and the detection band (9d) is respectively
Connected by microchannel (9f) with corresponding label area (9c), on the detection band (9d) along the flow direction of liquid successively
Equipped with detection reaction zone (9g) and reaction reference area (9h).
5. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 3, it is characterised in that：The transmitting circuit is set
Operational amplifier U1 and operational amplifier U2 are equipped with, the in-phase input end of operational amplifier U1 and the control signal of processor export
End connection, inverting input are connected through resistance R1 with power supply, and inverting input is also grounded through resistance R2, and operational amplifier U1's is defeated
Outlet is connected through base stages of the resistance R3 respectively with triode D1 and triode D2, and collector and the pulse power supply of triode D1 connect
Connect, the cathode of stepper motor (8) is moved forward and backward described in emitter connection, move forward and backward the anode and triode of stepper motor (8)
The collector connection of D2, the emitter ground connection of triode D2；
The control signal output of the inverting input of operational amplifier U2 and processor connects, in-phase input end through resistance R4 with
Power supply connects, and in-phase input end is also grounded through resistance R5, the output terminal of operational amplifier U2 through resistance R6 respectively with triode D3
Connected with the base stage of triode D4, the collector of triode D3 is connected with pulse power supply, is moved forward and backward described in emitter connection
The anode of stepper motor (8), the cathode for moving forward and backward stepper motor (8) are connected with the collector of triode D4, triode D4's
Emitter is grounded.
6. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The print module is
Thermal printer (6), the thermal printer (6) are connected by 232 interfaces with the type information output terminal of the processor, temperature-sensitive
The exit slot of printer (6) is communicated with printing single outlet (4).
7. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The testing agency sets
It is equipped with fluorescent optical sensor (10) and fluorescence excitation light source (11), institute's displacement system driving fluorescent optical sensor (10) and fluorescence excitation
Light source (11) is mobile, and the fluorescent optical sensor (10) is connected with the fluorescence information input terminal of processor, and the processor passes through light
Source control module controls the intensity of illumination of the fluorescence excitation light source (11)；
Institute's displacement system is provided with erecting bed (12) and left and right displacement stepper motor (13), the fluorescent optical sensor (10) and glimmering
Phot-luminescence source (11) is fixed on erecting bed (12), and left and right displacement stepper motor (13) driving erecting bed (12) left and right is moved
Dynamic, the processor controls the left and right displacement stepper motor (13) to work by controllor for step-by-step motor.
8. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The input and output mould
Block is capacitance touch screen (14), and the signal output part of the capacitance touch screen (14) connects with the information input/output terminal of the processor
Connect.
9. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The radio communication mold
Block is provided with 4G communication modules, bluetooth module and wifi communication modules.
10. the micro-fluidic record interpretoscope of self-absorption multichannel according to claim 2, it is characterised in that：The processor is also
GPS module is connected with, processor obtains positional information by GPS module, and the GPS communication module and the position of the processor are believed
Input terminal connection is ceased, positional information is sent to cloud data center by the processor by wireless communication module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720975898.3U CN207248747U (en) | 2017-08-07 | 2017-08-07 | The micro-fluidic record interpretoscope of self-absorption multichannel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720975898.3U CN207248747U (en) | 2017-08-07 | 2017-08-07 | The micro-fluidic record interpretoscope of self-absorption multichannel |
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| Publication Number | Publication Date |
|---|---|
| CN207248747U true CN207248747U (en) | 2018-04-17 |
Family
ID=61879014
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720975898.3U Active CN207248747U (en) | 2017-08-07 | 2017-08-07 | The micro-fluidic record interpretoscope of self-absorption multichannel |
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| Country | Link |
|---|---|
| CN (1) | CN207248747U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112230574A (en) * | 2020-07-30 | 2021-01-15 | 深圳加美生物有限公司 | Low-power-consumption multi-channel colloidal gold detection instrument circuit |
| WO2023050710A1 (en) * | 2021-09-28 | 2023-04-06 | 江苏汇先医药技术有限公司 | Multi-channel lamp detector and control method thereof |
-
2017
- 2017-08-07 CN CN201720975898.3U patent/CN207248747U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112230574A (en) * | 2020-07-30 | 2021-01-15 | 深圳加美生物有限公司 | Low-power-consumption multi-channel colloidal gold detection instrument circuit |
| WO2023050710A1 (en) * | 2021-09-28 | 2023-04-06 | 江苏汇先医药技术有限公司 | Multi-channel lamp detector and control method thereof |
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