CN207168636U - Conduction type flexible miniature support and medicine equipment - Google Patents

Conduction type flexible miniature support and medicine equipment Download PDF

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Publication number
CN207168636U
CN207168636U CN201720143336.2U CN201720143336U CN207168636U CN 207168636 U CN207168636 U CN 207168636U CN 201720143336 U CN201720143336 U CN 201720143336U CN 207168636 U CN207168636 U CN 207168636U
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China
Prior art keywords
drainage tube
conduction type
medicine
type flexible
cavity
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CN201720143336.2U
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Chinese (zh)
Inventor
陈福成
朱成敏
戴会新
张华书
孙云
王毅
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Wuhan Olympic Green New Biological Polytron Technologies Inc
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Wuhan Olympic Green New Biological Polytron Technologies Inc
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Abstract

It the utility model is related to technical field of medical instruments, more particularly, to a kind of conduction type flexible miniature support and medicine equipment, drainage tube including multi-cavity, the drainage tube of the multi-cavity passes through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, wherein, the drainage tube of the multi-cavity comprises at least a fluid passage, multiple medicine filled cavities and multiple medicine filled cavities, the miniature support passes through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, the fluid passage of miniature support is by guiding the aqueous humor of anterior chamber to flow into epichoroidal space to reach the purpose of reduction intraocular pressure.Meanwhile medicine filled cavity can effectively, enduringly be discharged medicine in fixed position, be greatly reduced fixed position propagation and the situation of inflammation.

Description

Conduction type flexible miniature support and medicine equipment
Technical field
Technical field of medical instruments is the utility model is related to, more particularly, to a kind of conduction type flexible miniature support and medical treatment Apparatus.
Background technology
At present, glaucoma is a kind of increased disease of the aqueous humor in eyes.In the eyes of health, ciliary process secretion room Water, then angle of the aqueous humor through cornea and iris.Glaucoma appears to be the result of trabecular network obstruction.Such obstruction can To be caused by cell or coming off for other remains.When aqueous humor is not discharged suitably from the net of obstruction, it will increase and make Into in eyes, pressure particularly on the blood vessel of optic nerve is led to increases.High pressure on blood vessel can cause retina neural Ganglion cell is dead, and ultimately results in blindness.
In correlation technique, for glaucoma surgical operation therapy when a kind of drainage system or shunting can be implanted into eye Pipe.The effect of the drainage system is to discharge aqueous humor from anterior chamber, so as to reduce intraocular pressure.The drainage system is typically with wound Property surgical method and be implanted into.According to operation as one, a thin slice is formed in a manner of surgery in sclera.The thin slice Fold back to form a small cavity, an isocon is embedded in eye by the thin slice.Such operation can be because of its implant It is big and have stronger traumatic, and various adverse events can be caused, such as infection and scar, result in the need for re-starting Operation.
Some shortcomings, and only medium success rate be present in device and process currently used for treating glaucoma.It is this Process has very big wound to eyes, also requires point-device Surgical technique, such as be properly positioned draw in position Flow device.In addition, this device of the drainage of bubble easily causes infection under from anterior chamber to the conjunctiva under sclera thin slice, and And it may block and stop operation.This may require re-starting operation to remove the device, and place another device, or Further surgical operation can be caused.In view of above-mentioned reason, it is necessary to be modified to the apparatus and method for treating glaucoma.
Certainly, also there are the introduction that some patent documents refer to similar drainage tube, with reference to shown in Fig. 1, shunting in correlation technique Pipe 105 is arranged in eyes, and aqueous humor flows to epichoroidal space after entering isocon 105 from anterior chamber 115.But the isocon is only Only it is to provide a fluid passage, following two point defect is present:
First, single-chamber isocon is implanted with to deform upon under the pressure of muscle for a long time, causes tube chamber to cave in stifled Plug;
2nd, isocon is after the implantation, it is possible to can cause local location that propagation and the situation of inflammation occurs, produce other Lesion.
Utility model content
The purpose of this utility model is to provide a kind of conduction type flexible miniature support and medicine equipment, to solve existing skill Single-chamber isocon present in art is implanted with to deform upon under the pressure of muscle for a long time, causes tube chamber to cave in stifled Plug;Isocon is after the implantation, it is possible to can cause local location that propagation and the situation of inflammation occurs, produce the skill of other lesions Art problem.
In order to solve the above technical problems, the utility model provides a kind of conduction type flexible miniature support, it includes multi-cavity Drainage tube, the drainage tube of the multi-cavity passes through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, Wherein, the drainage tube of the multi-cavity comprises at least:
One fluid passage, through of the fluid passage along the drainage tube are set, and it has inflow entrance and stream Outlet;
Multiple medicine filled cavities, multiple medicine filled cavities are arranged at the periphery of the fluid passage, and respectively along institute The circumferential insertion for stating drainage tube is set;
Multiple drug releasing pores, multiple drug releasing pores are opened on the outer wall of the drainage tube, and with its institute The medicine filled cavity of correspondence position is connected.
Further, the inside of the medicine filled cavity is provided with the packing space for being used for depositing medicine, and the medicine passes through The form of ultrasonic atomizatio is filled in the packing space inside the medicine filled cavity.
Further, the medicine includes:Mitomycin, liver mycin, heparin are mixed, rapamycin, PLA, polyglycolic acid One kind or any several combinations in copolymer, makrolon, phosphocholine, fluoropolymer.
Further, the cross sectional shape of the fluid passage is circular, ellipse or rectangle.
Further, the cross sectional shape of the medicine filled cavity is flat.
Further, the quantity of the medicine filled cavity is five.
Further, the drainage tube is made of biocompatible materials.
Further, limit assembly is provided with the outer wall of the drainage tube, the limit assembly is used to draw described in fixation Relative position of the flow tube in use state.
Further, mark component is provided with the outer wall of the drainage tube, the mark component is used to mark described draw Relative position of the flow tube in use state.
In order to solve the above technical problems, the utility model also provides a kind of medicine equipment, it includes conveying device, described defeated Device is sent to be used to convey described conduction type flexible miniature support, it equally includes the drainage tube of multi-cavity, the multi-cavity Drainage tube passes through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, wherein, the drainage of the multi-cavity Pipe comprises at least:One fluid passage, multiple medicine filled cavities and multiple drug releasing pores;The fluid passage is along the drainage The through of pipe is set, and it has inflow entrance and flow export;Multiple medicine filled cavities are arranged at the fluid passage Periphery, and set respectively along the circumferential insertion of the drainage tube;Multiple drug releasing pores are opened in the drainage tube On outer wall, and it is connected with the medicine filled cavity of its corresponding position.
Using above-mentioned technical proposal, the utility model has the advantages that:
The utility model provides a kind of conduction type flexible miniature support, an otch is formed on the cornea of eyes, by this Miniature support is fixed in the anterior chamber of eyes by the otch.The miniature support enters train of thought along from the scleral spur of anterior chamber's eyes Path in epistege passes through, and the fluid passage of miniature support is by guiding the aqueous humor of anterior chamber to flow into epichoroidal space to reach drop The purpose of low intraocular pressure.Meanwhile medicine filled cavity can effectively, enduringly be discharged medicine in fixed position, greatly Reduce fixed position propagation and the situation of inflammation.
Brief description of the drawings
, below will be right in order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art The required accompanying drawing used is briefly described in embodiment or description of the prior art, it should be apparent that, describe below In accompanying drawing be some embodiments of the present utility model, for those of ordinary skill in the art, do not paying creativeness On the premise of work, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 be eyes anterior chamber and back room a part of eyes sectional block diagram;
Fig. 2 is the viewgraph of cross-section of eyes;
Fig. 3 is the structural representation for the conduction type flexible miniature support that the utility model embodiment provides;
Fig. 4 is the side schematic view for the conduction type flexible miniature support that the utility model embodiment provides.
Reference:
1- fluid passages;2- medicine filled cavities;3- drug releasing pores.
Embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with accompanying drawing, it is clear that described Embodiment is the utility model part of the embodiment, rather than whole embodiments.Based on the embodiment in the utility model, sheet The every other embodiment that field those of ordinary skill is obtained under the premise of creative work is not made, belongs to this practicality Novel protected scope.
, it is necessary to explanation in description of the present utility model, term " " center ", " on ", " under ", it is "left", "right", " perpendicular Directly ", the orientation of the instruction such as " level ", " interior ", " outer " or position relationship are based on orientation shown in the drawings or position relationship, are only Described for the ease of description the utility model and simplifying, rather than instruction or imply signified device or element must have it is specific Orientation, with specific azimuth configuration and operation, therefore it is not intended that to limitation of the present utility model.In addition, term " the One ", " second ", " the 3rd " are only used for describing purpose, and it is not intended that instruction or hint relative importance.
, it is necessary to which explanation, unless otherwise clearly defined and limited, term " are pacified in description of the present utility model Dress ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integratedly Connection;Can be mechanical connection or electrical connection;Can be joined directly together, can also be indirectly connected by intermediary, It can be the connection of two element internals.For the ordinary skill in the art, on can understanding as the case may be State concrete meaning of the term in the utility model.
Specific embodiment of the present utility model is described in detail below in conjunction with accompanying drawing.It should be appreciated that herein Described embodiment is merely to illustrate and explained the utility model, is not limited to the utility model.
Embodiment one
In order to facilitate understanding, first the construction of the anterior chamber to eyes and back room is simply retouched between the present embodiment is introduced State.With reference to shown in Fig. 2, eyes are usually spherical, and are covered by sclera S outside it.Retina R is covered with later half in eyes In part.Retina recording light, and transmit a signal to brain via optic nerve.Eyes are largely full of and propped up by vitreum Support, vitreum is a kind of limpid, g., jelly-like material.
Elastic crystalline lens L is located near ocular region.Crystalline lens L provides the adjustment of focus, and is suspended in from eyelash In shape body CB pouch, ciliary body CB includes the muscle for changing crystalline lens focal length.Split by iris I in space before crystalline lens L Into two parts, iris controls lenticular aperture and reaches the light quantity of retina.Pupil is a hole for being located at iris I centers, Light passes through via pupil.Space between iris I and crystalline lens L is back room PC.Before space between iris I and cornea is Room AC.Anterior chamber and back room are full of the limpid fluid for being referred to as aqueous humor.
Ciliary body CB constantly forms aqueous humor by the secretion from blood vessel in back room PC.Aqueous humor in crystalline lens L and Anterior chamber is flowed into around iris I, and eyes are left by trabecular network, trabecular network is a kind of positioned at iris I and wall of eyeball angle The sieve texture of (angle is also referred to as room angle).Some aqueous humors are managed by girder net filtration into SchlemmShi, SchlemmShi Pipe is a passage aisle of the drainage into eyes vein.Smaller ones eventually pass through sclera (sclera road by ciliary body Line) venous circulation is added again afterwards.
As shown in Figure 3, Figure 4, the conduction type flexible miniature support that the present embodiment one provides, it includes the drainage of multi-cavity Pipe, the drainage tube of the multi-cavity pass through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, wherein, institute The drainage tube for stating multi-cavity comprises at least:
One fluid passage 1, through of the fluid passage 1 along the drainage tube are set, its have inflow entrance and Flow export, the fluid passage 1 is by guiding the aqueous humor of anterior chamber to flow into epichoroidal space to reach the purpose of reduction intraocular pressure.
Multiple medicine filled cavities 2, multiple medicine filled cavities 2 are arranged at the periphery of the fluid passage 1, and edge respectively The circumferential insertion of the drainage tube is set, and medicine filled cavity 2 can effectively, enduringly be discharged medicine in fixed position, It is greatly reduced fixed position propagation and the situation of inflammation;
Multiple drug releasing pores 3, multiple drug releasing pores 3 are opened on the outer wall of the drainage tube, and and its The medicine filled cavity 2 of corresponding position is connected.
It can be seen that a kind of drainage tube of multi-cavity of the present embodiment, central hollow allows aqueous humor to pass through, and porous and can ensures material Material it is sufficiently ductile, can keep aqueous humor drainage function indeformable for a long time, medicine filled cavity 2 can continue, stable release Put medicine and reduce the probability that lesion occurs for support fixed position.
The conduction type flexible miniature support, it is empty that the filling for being used to deposit medicine is provided with the inside of the medicine filled cavity 2 Between, the medicine is filled in the packing space inside the medicine filled cavity 2 by the form of ultrasonic atomizatio.
Specifically, the medicine includes:Mitomycin, liver mycin, heparin are mixed, rapamycin, PLA, polyglycolic acid are common One kind or any several combinations in polymers, makrolon, phosphocholine, fluoropolymer.
For the concrete structure and size of conduction type flexible miniature support, can be adjusted flexibly according to actual conditions. Illustrated below with wherein several preferable examples.
Preferably, the cross sectional shape of the fluid passage 1 is circular, ellipse or rectangle.Fluid in the present embodiment The cross sectional shape of path 1 is circle.
Preferably, the cross sectional shape of the medicine filled cavity 2 is flat.Such as:It is flat sharp oval that it is shaped as two Shape, certain other shapes can also, will not enumerate herein.
Specifically, the quantity of the medicine filled cavity 2 is five, and five medicine filled cavities 2 are evenly distributed in the stream The surrounding of body path 1.
In the present embodiment, the drainage tube is made of biocompatible materials.
Such as:The drainage tube can use polyimides, ceramics, the organic silicon rubber or stainless of good biocompatibility Steel or Nitinol etc. biocompatible materials.
Certainly, the drainage tube can also use other materials or material, such as:Other suitable polymer, metal, gold Belong to alloy, or their various combinations.Other rapidoprints or material include silicones, PTFE, various fluoropolymers, FEP, the FEP of the laminated node into ePTFE, silver coating (such as via CVD techniques), gold, prolene/polyolefin, Polyethylene (methyl methacrylate) (PMMA), acrylic resin, polyethylene terephthalate (PET), polyethylene (PE), PLLA and parylene etc..
Further, limit assembly is provided with the outer wall of the drainage tube, the limit assembly is used to draw described in fixation Relative position of the flow tube in use state.Limit assembly can be excrescence, wing, tusk or skewer, and they are intervened Human body, drainage tube is maintained at correct position.
Further, mark component is provided with the outer wall of the drainage tube, the mark component is used to mark described draw Relative position of the flow tube in use state.The drainage tube can carry one or more visual, profile scanning, echo Or radiopaque mark component, mark component can be by being transferred to its applicable mark by above mentioned any device Knowledge system helps to position.
Embodiment two
The present embodiment two provides a kind of medicine equipment, and it includes conveying device, and the conveying device is used to convey embodiment Conduction type flexible miniature support described in one.
Specifically, the conduction type flexible miniature support includes the drainage tube of multi-cavity, the drainage tube of the multi-cavity along Passed through from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, wherein, the drainage tube of the multi-cavity comprises at least:
One fluid passage 1, through of the fluid passage 1 along the drainage tube are set, its have inflow entrance and Flow export, the fluid passage 1 is by guiding the aqueous humor of anterior chamber to flow into epichoroidal space to reach the purpose of reduction intraocular pressure.
Multiple medicine filled cavities 2, multiple medicine filled cavities 2 are arranged at the periphery of the fluid passage 1, and edge respectively The circumferential insertion of the drainage tube is set, and medicine filled cavity 2 can effectively, enduringly be discharged medicine in fixed position, It is greatly reduced fixed position propagation and the situation of inflammation;
Multiple drug releasing pores 3, multiple drug releasing pores 3 are opened on the outer wall of the drainage tube, and and its The medicine filled cavity 2 of corresponding position is connected.
As for other features, have described in detail above, here is omitted.
Finally it should be noted that:Various embodiments above is only to illustrate the technical solution of the utility model, rather than it is limited System;Although the utility model is described in detail with reference to foregoing embodiments, one of ordinary skill in the art should Understand:It can still modify to the technical scheme described in foregoing embodiments, either to which part or whole Technical characteristic carries out equivalent substitution;And these modifications or replacement, the essence of appropriate technical solution is departed from this practicality newly The scope of each embodiment technical scheme of type.

Claims (10)

1. a kind of conduction type flexible miniature support, it is characterised in that the drainage tube including multi-cavity, the drainage tube of the multi-cavity Passed through along from the path that the scleral spur of anterior chamber's eyes enters in epichoroidal space, wherein, the drainage tube of the multi-cavity is at least Including:
One fluid passage, through of the fluid passage along the drainage tube are set, and it has inflow entrance and flow export;
Multiple medicine filled cavities, multiple medicine filled cavities are arranged at the periphery of the fluid passage, and draw respectively along described The circumferential insertion of flow tube is set;
Multiple drug releasing pores, multiple drug releasing pores are opened on the outer wall of the drainage tube, and with its corresponding to The medicine filled cavity of position is connected.
2. conduction type flexible miniature support according to claim 1, it is characterised in that the inside of the medicine filled cavity is set There is the packing space for depositing medicine, the medicine is filled in inside the medicine filled cavity by the form of ultrasonic atomizatio In packing space.
3. conduction type flexible miniature support according to claim 2, it is characterised in that the medicine includes:Mitomycin, Liver mycin, heparin are mixed, in rapamycin, PLA, co-glycolic acid, makrolon, phosphocholine, fluoropolymer A kind of or any several combinations.
4. conduction type flexible miniature support according to claim 1, it is characterised in that the cross sectional shape of the fluid passage For circular, ellipse or rectangle.
5. conduction type flexible miniature support according to claim 1, it is characterised in that the section shape of the medicine filled cavity Shape is flat.
6. conduction type flexible miniature support according to claim 5, it is characterised in that the quantity of the medicine filled cavity is Five.
7. conduction type flexible miniature support according to claim 1, it is characterised in that the drainage tube uses bio-compatible Property material is made.
8. conduction type flexible miniature support according to claim 1, it is characterised in that set on the outer wall of the drainage tube Limited location component, the limit assembly are used to fix relative position of the drainage tube in use state.
9. conduction type flexible miniature support according to claim 1, it is characterised in that set on the outer wall of the drainage tube There is mark component, the mark component is used to mark the drainage tube in the relative position of use state.
10. a kind of medicine equipment, it is characterised in that including conveying device, the conveying device is used to convey such as claim 1-9 Any one of conduction type flexible miniature support.
CN201720143336.2U 2017-02-16 2017-02-16 Conduction type flexible miniature support and medicine equipment Active CN207168636U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106963543A (en) * 2017-02-16 2017-07-21 武汉奥绿新生物科技股份有限公司 Conduction type flexible miniature support and medicine equipment
CN114129769A (en) * 2021-09-22 2022-03-04 海思盖德(苏州)生物医学科技有限公司 Artificial aqueous humor micro-drainage tube with drug slow-release function and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106963543A (en) * 2017-02-16 2017-07-21 武汉奥绿新生物科技股份有限公司 Conduction type flexible miniature support and medicine equipment
CN114129769A (en) * 2021-09-22 2022-03-04 海思盖德(苏州)生物医学科技有限公司 Artificial aqueous humor micro-drainage tube with drug slow-release function and preparation method thereof
CN114129769B (en) * 2021-09-22 2022-08-05 海思盖德(苏州)生物医学科技有限公司 Artificial aqueous humor micro-drainage tube with drug slow-release function and preparation method thereof

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Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant
PE01 Entry into force of the registration of the contract for pledge of patent right
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of utility model: Drainage type flexible micro stent and medical devices

Effective date of registration: 20210624

Granted publication date: 20180403

Pledgee: Industrial Bank Limited by Share Ltd. Wuhan branch

Pledgor: WUHAN GREENOVO BIOTECHNOLOGY Co.,Ltd.

Registration number: Y2021420000048