CN207114561U - Full-automatic chemiluminescence immunoassay detection execution device - Google Patents
Full-automatic chemiluminescence immunoassay detection execution device Download PDFInfo
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- CN207114561U CN207114561U CN201720315178.4U CN201720315178U CN207114561U CN 207114561 U CN207114561 U CN 207114561U CN 201720315178 U CN201720315178 U CN 201720315178U CN 207114561 U CN207114561 U CN 207114561U
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- cup groove
- rotating disk
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- chemiluminescence immunoassay
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 21
- 238000001514 detection method Methods 0.000 title claims description 30
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 48
- 238000005070 sampling Methods 0.000 claims abstract description 11
- 238000005259 measurement Methods 0.000 claims abstract description 10
- 230000003287 optical effect Effects 0.000 claims abstract description 10
- 239000000758 substrate Substances 0.000 claims abstract description 10
- 238000011534 incubation Methods 0.000 claims description 7
- 238000003556 assay Methods 0.000 claims description 6
- 239000006249 magnetic particle Substances 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 230000000975 bioactive effect Effects 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 238000004140 cleaning Methods 0.000 abstract description 2
- 238000012031 short term test Methods 0.000 abstract 1
- 230000005540 biological transmission Effects 0.000 description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000012123 point-of-care testing Methods 0.000 description 2
- 239000011343 solid material Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model provides a full-automatic chemiluminescence immunoassay detects actuating device can solve current full-automatic chemiluminescence immunoassay and detects actuating device structure complicacy, the volume is great, with high costs and can't realize bedside short-term test's technical problem. It includes reaction cup and reagent cup bear and moving mechanism, sample sampling mechanism, reagent application of sample mechanism, wiper mechanism, incubate mechanism, substrate application of sample mechanism and optical measurement mechanism, its characterized in that: the bearing and moving mechanism of the reagent cup and the reaction cup comprises a rotary disc and a driving mechanism for driving the rotary disc to rotate, reagent cup grooves, reaction cup grooves and sample cup grooves which are all annular and concentrically distributed are formed in the rotary disc, the sample sampling mechanism, the reagent sampling mechanism, the cleaning mechanism, the substrate sampling mechanism and the optical measurement mechanism are sequentially distributed along the periphery of the rotary disc, and the temperature control mechanism is fixed at the bottom of the rotary disc and controls the temperature of the rotary disc.
Description
Technical field
It the utility model is related to chemiluminescence immune assay field, and in particular to a kind of automatic chemiluminescence immunoassay
Detect performs device.
Background technology
Existing automatic chemiluminescence immunoassay detects performs device, typically by sample bit of storage, reagent bit of storage,
Sample pipetting volume mechanism, reagent pipetting volume mechanism, incubation reaction mechanism, wiper mechanism, chemiluminescence measuring mechanism, cup transmission mechanism
And computer control system composition, it is characterized in, whole chemiluminescence immune assay process feeds from reaction cup, is loaded, added
Reagent, incubation, cleaning can realize automatic business processing until chemiluminescence measures, and without manual operation, have treating capacity greatly, certainly
The advantages that dynamicization degree is high.But existing detection performs device is that each sample, reagent element are divided into different institutions, needs to distinguish
There is provided, for example, liquid reagent and solid phase carrier be not integration, so the complicated of instrument, volume are larger, operating cost compared with
Height, especially it is not suitable for small clinical laboratory and bedside quick detection(POCT)Application, the clinical detection of practical application is just
Victory is poor.
Utility model content
In view of the above-mentioned problems, the utility model provides a kind of automatic chemiluminescence immunoassay detection performs device,
It can solve that existing automatic chemiluminescence immunoassay detection performs device is complicated, volume is larger, cost is high, detection effect
Rate is low and can not realize the technical problem that sample enters at random, especially suitable for bedside quick detection(POCT)And small clinical
The application in laboratory.
Its technical scheme is such:Performs device includes reaction cup and reagent carrying and motion, sample sampler
Structure, reagent pipetting volume mechanism, wiper mechanism, incubation mechanism, substrate sample charging mechanism and optical measurement mechanism, it is characterised in that:It is described
Reagent cup includes the drive mechanism of rotating disk and driving rotating disk rotation with the carrying of reacting hole cup with motion, is opened on the rotating disk
Provided with reagent cup groove, reaction cup groove and specimen cup groove annular in shape and be distributed with one heart, the sample sampling mechanism, the examination
Agent sample charging mechanism, the wiper mechanism, the substrate sample charging mechanism and the optical measurement mechanism are successively along the outer of the rotating disk
Week distribution, the incubation mechanism are fixed on the rotating disk bottom, carry out temperature control to the rotating disk.
Further, the rotating disk is circular or annular, and the reagent cup groove, reaction cup groove and specimen cup groove are along rotating disk
Center is annularly distributed;The reagent cup groove, reaction cup groove are located at the outer ring of the rotating disk, and the specimen cup groove turns positioned at described
The inner ring of disk, single reaction cup groove the radially extending along the rotating disk.
Further, sample cell position is arranged with reagent cup groove position, reagent cup groove dislocation position so that reaction cup groove and reagent cup
For groove not on same radius, the bar code reading device realized positioned at center of turntable point can read sample and reagent letter automatically
Breath.
Further, the reagent cup groove and reaction cup groove are integrated in one.
Further, in the reaction cup groove, the quantity of reaction cup groove is 1 to 3;The quantity of the reagent cup groove is 1
To 6.
Further, reaction cup is provided with the reaction cup groove, the reaction cup endoperidium there are bioactive materials.
Further, reaction cup is provided with the reaction cup groove, magnetic particle or other forms are provided with the reaction cup
Granule solid material, the magnetic particle, the other forms granule solid material on be coated with bioactive materials.
Further, the rotating disk can clockwise, rotate counterclockwise.
Further, the center of turntable point is equipped with bar code reading and takes device, can read sample and reagent information automatically.
Further, the chemiluminescence immune assay device also includes useless cup unloading device.
The utility model is by the way that specimen cup groove, reagent cup groove and reaction cup groove are integrated on rotating disk, and by sample
Sampling mechanism, reagent pipetting volume mechanism, wiper mechanism, substrate sample charging mechanism and optical measurement mechanism are successively along the periphery of rotating disk point
Cloth, and then the transfer path of each reagent is shortened, the overall integrated level of device is improved, has simplified device overall structure, is reduced
Overall volume, reduces cost;Meanwhile sample sampling mechanism, reagent pipetting volume mechanism, wiper mechanism, incubation mechanism, substrate add
The detection operation of model machine structure and optical measurement mechanism to the different station testing sample on rotating disk is carried out simultaneously, is not interfere with each other, no
It only can effectively shorten the detection stand-by period that sample corresponds to each mechanism, improve detection efficiency, and can be to inoperative
The specimen cup groove of station is loaded, and realizes the random entrance of sample, and this kind of random entrance can be given in non-stopped status
Lower realization.
Detection performs device of the present utility model, a reagent cup groove being integrated in one and reaction cup groove can be used for one kind
The implementation of detection project;By loading different reaction cups and reagent strip, can not only to a sample simultaneously carry out it is multiple not
Same immune detection project, and different immune detection projects, or multiple samples can be carried out simultaneously to multiple samples
Carry out the detection of same detection project simultaneously.
Brief description of the drawings
Fig. 1 is of the present utility model comprising reagent cup and the carrying of reacting hole cup and the structural representation of motion.
Fig. 2 is the dimensional structure diagram of automatic chemiluminescence immunoassay performs device of the present utility model.
Fig. 3 is the overlooking the structure diagram of automatic chemiluminescence immunoassay performs device of the present utility model.
Embodiment
As shown in Figure 1, Figure 2 and Figure 3, a kind of automatic chemiluminescence immunoassay detection performs device, it includes pedestal
90, and be supported in the cup transmission mechanism 10 of pedestal 90, sample sampling mechanism 20, reagent pipetting volume mechanism 30, wiper mechanism 40,
Be incubated mechanism, substrate sample charging mechanism 50 and optical measurement mechanism 60, cup transmission mechanism 10 include annular rotating disk 11 and
The drive mechanism of driving rotating disk rotation, offer on rotating disk along center of turntable is annular in shape and is distributed with one heart reagent cup groove, anti-
Answer cup groove and specimen cup groove 13, sample sampling mechanism 20, reagent pipetting volume mechanism 30, wiper mechanism 40, the and of substrate sample charging mechanism 50
Optical measurement mechanism 60 along the peripheral distribution of rotating disk 11, is incubated mechanism and set and be fixed on rotating disk bottom, the entirety of rotating disk 11 is entered successively
Row heating.
Reagent cup groove and reaction cup groove are integrated in one, as shown in figure 12, positioned at the outer ring of rotating disk 11, specimen cup groove 13
Positioned at the inner ring of rotating disk, single the radially extending along rotating disk of cup groove 12, the setting enables to arrange more in limited space
More reagent cup, reaction cup and specimen cups, detection scale is improved, and then further improve detection efficiency.
Chemiluminescence immune assay device also includes bar code reading device 80, and bar code reading device 80 is located at turning for annular
The center of disk 11 is simultaneously supported on pedestal 90, and reagent cup groove and reaction cup groove 12 and the specimen cup groove 13 being integrated in one interlock
Distribution, realize that the bar code reading device positioned at center of turntable point can read sample and reagent information automatically.
Chemiluminescence immune assay device also includes useless cup unloading device 70, after sample is measured, specimen cup and
Correlated response cup is taken out by useless cup unloading device, to improve the automaticity of device.
Claims (10)
1. a kind of automatic chemiluminescence immunoassay detects performs device, it includes reaction cup and reagent cup carrying and fitness machine
Structure, sample sampling mechanism, reagent pipetting volume mechanism, wiper mechanism, incubation mechanism, substrate sample charging mechanism and optical measurement mechanism, its
It is characterised by:The driving machine that the carrying of the reagent cup and reaction cup includes rotating disk with motion and driving rotating disk rotates
Structure, reagent cup groove, reaction cup groove and specimen cup groove annular in shape and be distributed with one heart, the sample are offered on the rotating disk
Sampling mechanism, the reagent pipetting volume mechanism, the wiper mechanism, the substrate sample charging mechanism and the optical measurement mechanism are successively
Along the peripheral distribution of the rotating disk, the incubation mechanism is fixed on the rotating disk bottom, carries out temperature control to the rotating disk.
A kind of 2. automatic chemiluminescence immunoassay detection performs device according to claim 1, it is characterised in that:Institute
Rotating disk is stated annularly to be distributed along center of turntable for circular or annular, the reagent cup groove, reaction cup groove and specimen cup groove.
A kind of 3. automatic chemiluminescence immunoassay detection performs device according to claim 2, it is characterised in that:Institute
State reagent cup groove, reaction cup groove is located at the outer ring of the rotating disk, the specimen cup groove is located at the inner ring of the rotating disk, single described
Reaction cup groove radially extends along the rotating disk.
A kind of 4. automatic chemiluminescence immunoassay detection performs device according to claim 2, it is characterised in that sample
Arranged with reagent cup groove position, reagent cup groove dislocation position product groove position.
A kind of 5. automatic chemiluminescence immunoassay detection performs device according to claim 2, it is characterised in that:Institute
State reagent cup groove and reaction cup groove is integrated in one.
A kind of 6. automatic chemiluminescence immunoassay detection performs device according to claim 5, it is characterised in that:Instead
The quantity for answering cup groove is 1 to 3, and the quantity of reagent cup groove is 1 to 6.
A kind of 7. automatic chemiluminescence immunoassay detection performs device according to claim 2, it is characterised in that:Institute
State in reaction cup groove and be provided with reaction cup, the reaction cup endoperidium there are bioactive materials.
A kind of 8. automatic chemiluminescence immunoassay detection performs device according to claim 2, it is characterised in that:Institute
State and reaction cup is provided with reaction cup groove, be provided with magnetic particle in the reaction cup, bioactivity is coated with the magnetic particle
Material.
A kind of 9. automatic chemiluminescence immunoassay detection performs device according to claim 1, it is characterised in that:Institute
State rotating disk can clockwise, rotate counterclockwise.
A kind of 10. automatic chemiluminescence immunoassay detection performs device according to claim 1, it is characterised in that:
The chemiluminescence immune assay detection performs device also includes useless cup unloading device, and the center of turntable point is equipped with bar code reading
Take device.
Priority Applications (1)
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CN201720315178.4U CN207114561U (en) | 2017-03-29 | 2017-03-29 | Full-automatic chemiluminescence immunoassay detection execution device |
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CN201720315178.4U CN207114561U (en) | 2017-03-29 | 2017-03-29 | Full-automatic chemiluminescence immunoassay detection execution device |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110860540A (en) * | 2018-08-27 | 2020-03-06 | 深圳迎凯生物科技有限公司 | Cleaning method and sample analysis method |
CN114354910A (en) * | 2021-12-13 | 2022-04-15 | 杭州睿丽科技有限公司 | Multichannel chemiluminescence immunoassay analyzer |
-
2017
- 2017-03-29 CN CN201720315178.4U patent/CN207114561U/en active Active
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110860540A (en) * | 2018-08-27 | 2020-03-06 | 深圳迎凯生物科技有限公司 | Cleaning method and sample analysis method |
CN110860540B (en) * | 2018-08-27 | 2021-07-27 | 深圳迎凯生物科技有限公司 | Cleaning method and sample analysis method |
CN114354910A (en) * | 2021-12-13 | 2022-04-15 | 杭州睿丽科技有限公司 | Multichannel chemiluminescence immunoassay analyzer |
CN114354910B (en) * | 2021-12-13 | 2023-08-11 | 杭州睿丽科技有限公司 | Multichannel chemiluminescence immunity analyzer |
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