CN207085090U - A kind of cobalt zirconium gold mark implant and gold mark implanted device - Google Patents
A kind of cobalt zirconium gold mark implant and gold mark implanted device Download PDFInfo
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- CN207085090U CN207085090U CN201720111271.3U CN201720111271U CN207085090U CN 207085090 U CN207085090 U CN 207085090U CN 201720111271 U CN201720111271 U CN 201720111271U CN 207085090 U CN207085090 U CN 207085090U
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- cobalt zirconium
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Abstract
The utility model provides a kind of cobalt zirconium gold mark implant, is related to implantable medical devices technical field.Cobalt zirconium gold mark implant includes golden sample body, and the golden sample body is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines for increasing friction；The outer surface of the golden sample body is additionally provided with medicine layer.In oncotherapy operation consent, cobalt zirconium gold mark implant is implanted to focus or its surrounding tissue, because lines increases the frictional force of cobalt zirconium gold mark implant and tissue, and metallic cobalt zirconium has blocking property for X-ray, medical personnel can be helped to be accurately tracked by the position of tumour, the purpose for reach fast positioning, precisely treating in Patients During Radiotherapy is implemented；Meanwhile medicine layer release high-purity medicament molecule is directly absorbed by focus, has auxiliary therapeutic action, suppress or kill tumour cell, improve operation and therapeutic effect.On this basis, the utility model additionally provides a kind of gold mark implanted device.
Description
Technical field
It the utility model is related to implantable medical devices technical field, more particularly to a kind of cobalt zirconium gold mark implant and gold mark
Implanted device.
Background technology
The method of current oncotherapy includes 5 kinds of means：Operative treatment, radiotherapy, chemotherapy, traditional Chinese medicine and life
Thing immunotherapy.Wherein, radiotherapy, radiotherapy is also abbreviated by, belongs to local therapeutic approaches, though the only history of decades,
Development is very fast.
In the case where CT images technology and technical development of computer help, radiotherapy technology by two-dimentional radiotherapy develop into three-dimensional radiotherapy,
Four-dimensional radiotherapy technology, Radiotherapy dosimetry distribution also develop into the agent in volume dose distribution, and volume dose distribution by dose point
Amount is adjusted strong.As SRT (SRT) includes three dimensional conformal radiation therapy (3DCRT), three-dimensional conformal intensity modulated radiation therapy (IMRT)；
Stereotaxic radiosurgery (SRS) includes X knives (X-knife), gamma knife (Y knives) and ejected wave knife (Cyber Knife), its feature
It is three-dimensional, small open country, boundling, gradation, high-dose irradiation.Modern medical service technology is maked rapid progress, and radiotherapy have also appeared proton and control
The treatment side of the new masters such as treatment, heavy particle therapy, linear accelerator, adaptive radiotherapy, termed image-guided radiotherapy and spiral-fault radiotherapy
Method, above-mentioned radiotheraping method is required to faster do.se fall outside the positioning precision higher to focus and target area, if in image
On not can determine that the position of tumour, cannot also implement high-precision treatment.
Therefore, in order to show the anatomical position of tumour, before the treatment, implanted metal mark generally around tumor tissues or its
Remember thing, to be capable of the position of tracking of knub during rich knife treatment match, implement not only fast but also accurately treat.
However, because metal marker composition granule is smaller and surface is smooth, particular organization around implantation tumour tissue or its
Afterwards, metal marker thing easily slides, and influences to detect locating effect.
Utility model content
The purpose of this utility model is to provide a kind of cobalt zirconium gold mark implant and gold mark implanted device, to solve existing skill
Metal marker thing in art is existing after implantation tumour tissue or its surrounding tissue, is easily shifted over, influences locating effect
Technical problem.
To achieve these goals, the utility model uses following technical scheme：
A kind of cobalt zirconium gold mark implant provided by the utility model, including golden sample body, the golden sample body is by metallic cobalt
Zirconium is made, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines for increasing friction；The golden sample body
Outer surface be additionally provided with medicine layer.
Further, the gold mark body interior sets cavity, and side wall is provided with hollow out through hole；Medicine built in the cavity
Thing is sustained case.The technical scheme has technical effect that：Medicament slow release case built in cavity can be put into the tumour medicine of high-purity,
Medicine is outwards discharged by the hollow out through hole of side wall, the medicine layer collective effect with the external side wall of golden sample, suppresses even to kill
The tumour cell of human body.
Preferably, the lines is cross, T-shaped and/or V-arrangement.The technical scheme has technical effect that：Cross, T
Fiber class loading connection in the lines and human body of shape and/or V-arrangement is more close, is less likely to occur to slide after fixed.
Preferably, the lines is criss-cross, rhombus and/or triangle.The technical scheme has technical effect that：Grid
The lines of shape, rhombus and/or triangle is connected more close with tissue, is less likely to occur to slide after fixed.
Preferably, the lines is hemispherical and/or cylindric.The technical scheme has technical effect that：It is hemispherical and/
Or columned lines realizes preferable adhesion with the dense tissue in human body.Above-mentioned a variety of lines can be according to different human body groups
Knit and use targeted specifically, reached optimal detection locating effect.
Further, the lines is raised or groove.The technical scheme has technical effect that：Lines could be arranged to
Raised or groove, convex shaped lines stability is preferable, and groove type lines tissue is damaged it is smaller.
Distinguishingly, can also golden sample body shell engraving rotation either intersect screw thread, explosion type needle-like raised line or
The needle-like raised line that axis is randomly distributed.
Preferably, the diameter range in the golden sample body cross section is more than or equal to 0.1 millimeter, less than or equal to 1.5 millimeters；Institute
The length range for stating golden sample body is more than or equal to 0.1 millimeter, less than or equal to 10 millimeters.The technical scheme has technical effect that：
According to the data of Clinical practice, it is more applicable that golden sample body is arranged to above appearance and size data, not only increases friction and improves
Stability, the injection implantation of golden sample body is not influenceed also.
Further, the medicine layer is adhered on the golden sample body by connecting oxidant layer.The technology effect of the technical scheme
Fruit is：Due to golden sample body small volume itself, by the mode operating difficulties such as spraying, inserting, and by bonding way not
The property of medicine of medicine is not only interfered with, and can be discharged medicine dissolving in tissue；It is in addition, external in golden sample
Successively set the mode of production of bond layer and medicine layer that also there is very high efficiency.
Further, the connection oxidant layer is made a living thing adhesive phase.The technical scheme has technical effect that：Bioadhesive
With common splicing function and special Biomedical function, safe to the human body, reliable, non-toxic, nothing three causes (carcinogenic, cause
Abnormal, mutagenesis), there is good biocompatibility, do not stimulate and can gradually degrade, absorb and be metabolized.
The utility model additionally provides a kind of gold mark implanted device, including sleeve pipe and pushes pin；Described sleeve pipe is socketed in described
Push pin outer, the internal diameter of described sleeve pipe is straight more than the cross section of cobalt zirconium according to any one of claims 1 to 9 gold mark implant
Footpath, and the diameter in twice of cross section, the shell of described sleeve pipe are provided with graduation mark, the end of described sleeve pipe is sharp
Shape.
The beneficial effects of the utility model are：
1st, the material selection metallic cobalt zirconium of golden sample body, not only due to metallic cobalt zirconium has the effect of blocking to X-ray, can be put
Equipment is treated to identify and realize good tracking；Importantly, metallic cobalt zirconium possesses good biocompatibility, implantation disclosure satisfy that
The other conditions such as biological condition that the metal alloy of human body should have, mechanical condition, electrochemical conditions；
2nd, the profile of golden sample body is arranged to capsule shape or cydariform, is on the one hand easy to set in the outer surface of golden sample body
Lines is put, increases the friction with tissue and avoids sliding；On the other hand its surface area is added, more curative can be bonded
Thing；
3rd, by setting lines on the surface of cobalt zirconium gold mark implant, increase cobalt zirconium gold mark implant and tissue are rubbed
Power is wiped, prevents cobalt zirconium gold mark implant from sliding, ensures the accuracy of detection positioning；
4th, medicine, auxiliary treatment and operation are bonded on the surface of cobalt zirconium gold mark implant, improve curative effect.
The 5th, cobalt zirconium gold mark implant is put into the internal diameter of gold mark implanted device middle sleeve, by the graduation mark of sleeve shell,
Reuse to push pin and cobalt zirconium gold mark implant can be implanted to the ad-hoc location of tissue.
Brief description of the drawings
, below will be to embodiment in order to illustrate more clearly of the technical scheme of the utility model embodiment
The required accompanying drawing used is briefly described in description.It should be evident that drawings in the following description are of the present utility model
Some embodiments, for those of ordinary skill in the art, on the premise of not paying creative work, can also basis
These accompanying drawings obtain other accompanying drawings.
Fig. 1 is the structural representation for the cobalt zirconium gold mark implant that the utility model embodiment one, three provides；
Fig. 2 is the structural representation for the cobalt zirconium gold mark implant that the utility model embodiment two provides；
Fig. 3 is the structural representation for the cobalt zirconium gold mark implant that the utility model embodiment four provides；
Fig. 4 is the longitudinal sectional view of the lines for the cobalt zirconium gold mark implant that the utility model embodiment five provides；
Fig. 5 is the partial enlarged drawing at K in Fig. 4；
Fig. 6 is the structural representation that gold provided by the utility model marks implanted device.
Reference：
1- gold sample bodies；2- medicine layers；3- lines；
4- connection oxidant layer；5- sleeve pipes；6- pushes pin；
7- graduation marks；8- hollow out through holes.
Embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with accompanying drawing, it is clear that described
Embodiment is the utility model part of the embodiment, rather than whole embodiments.Based on the embodiment in the utility model, sheet
The every other embodiment that field those of ordinary skill is obtained under the premise of creative work is not made, belongs to this practicality
Novel protected scope.
, it is necessary to explanation in description of the present utility model, term " " center ", " on ", " under ", it is "left", "right", " perpendicular
Directly ", the orientation of the instruction such as " level ", " interior ", " outer " or position relationship are based on orientation shown in the drawings or position relationship, are only
Described for the ease of description the utility model and simplifying, rather than instruction or imply signified device or element must have it is specific
Orientation, with specific azimuth configuration and operation, therefore it is not intended that to limitation of the present utility model.In addition, term " the
One ", " second ", " the 3rd " are only used for describing purpose, and it is not intended that instruction or hint relative importance.
, it is necessary to which explanation, unless otherwise clearly defined and limited, term " are pacified in description of the present utility model
Dress ", " connected ", " connection " should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integratedly
Connection；Can be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected by intermediary,
It can be the connection of two element internals.For the ordinary skill in the art, above-mentioned art can be understood with concrete condition
Concrete meaning of the language in the utility model.
The accompanying drawing of cobalt zirconium gold mark implant of the present utility model is as follows：
Fig. 1 is the structural representation for the cobalt zirconium gold mark implant that the utility model embodiment one, three provides；Fig. 2 is this reality
The structural representation of the cobalt zirconium gold mark implant provided with new embodiment two；Fig. 3 is what the utility model embodiment four provided
The structural representation of cobalt zirconium gold mark implant；Fig. 4 is the lines for the cobalt zirconium gold mark implant that the utility model embodiment five provides
Longitudinal sectional view；Fig. 5 is the partial enlarged drawing at K in Fig. 4；Fig. 6 is the knot that gold provided by the utility model marks implanted device
Structure schematic diagram.
Embodiment one：
As shown in Figure 1,5, cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, Jin Biao
Body 1 is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction
(lines 3 only marks sub-fraction in figure).In addition, the outer surface of golden sample body 1 is additionally provided with for auxiliary treatment and operation
Medicine layer 2.
In the prior art, either SRT, stereotaxic radiosurgery, or proton therapeutic, again
The oncotherapy side of the new masters such as ion treatment, linear accelerator, adaptive radiotherapy, termed image-guided radiotherapy and spiral-fault radiotherapy
Method, faster do.se fall outside the positioning precision higher to focus and target area is required to, if not can determine that on image swollen
The position of knurl, it cannot also implement high-precision treatment.And existing metal marker thing is being planted because particle is smaller and surface is smooth
Enter tumor tissues or around it after particular organization, metal marker thing easily slides, and influences to detect locating effect.
Cobalt zirconium gold mark implant provided by the utility model, has the following advantages that：
1st, the material selection metallic cobalt zirconium of golden sample body 1, there is the effect of blocking to X-ray, can be identified by radiotherapy apparatus and real
Now good tracking；
2nd, the profile of golden sample body 1 is arranged to capsule shape or cydariform, be on the one hand easy in the outer surface of golden sample body 1
Lines 3 is set, increases the friction with tissue and avoids sliding；On the other hand its surface area is added, more control can be bonded
Treat medicine；
3rd, by setting lines 3 on the surface of cobalt zirconium gold mark implant, increase cobalt zirconium gold mark implant and tissue
Frictional force, prevent cobalt zirconium gold mark implant from sliding, ensure the accuracy of detection positioning；
4th, medicine, auxiliary treatment and operation are bonded on the surface of cobalt zirconium gold mark implant, improve curative effect.
Embodiment two：
As shown in Fig. 2 cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, golden sample
Body 1 is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction.Separately
Outside, the golden inside of sample body 1 sets cavity, and side wall is provided with hollow out through hole 8 (hollow out through hole 8 only marks sub-fraction in figure),
Medicament slow release case built in cavity.Wherein, the medicament slow release case built in cavity can be put into the tumour medicine of high-purity, and medicine passes through side
The hollow out through hole 8 of wall outwards discharges, the collective effect of medicine layer 2 with the golden lateral wall of sample body 1, suppresses even to kill the swollen of human body
Oncocyte.
Embodiment three：
As shown in Figure 1, 2, cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, Jin Biao
Body 1 is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction.
In addition, the outer surface of golden sample body 1 is additionally provided with the medicine layer 2 for auxiliary treatment and operation.
Wherein, lines 3 (lines 3 only marks sub-fraction in figure) is cross, T-shaped and/or V-arrangement.In the present embodiment,
The lines 3 of cross, T-shaped and/or V-arrangement is connected more close with the fiber class loading in human body, is less likely to occur to slide after fixed
Move.
Example IV：
As shown in figure 3, cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, golden sample
Body 1 is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction.Separately
Outside, the outer surface of golden sample body 1 is additionally provided with the medicine layer 2 for auxiliary treatment and operation.
Wherein, lines 3 (lines 3 only marks sub-fraction in figure) is criss-cross, rhombus and/or triangle.In this implementation
Example in, the lines 3 of criss-cross, rhombus and/or triangle be connected with the fatty class loading in human body it is more close, fixation after do not allow
Easily slide.
Embodiment five：
As shown in figure 4, cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, golden sample
Body 1 is made up of metallic cobalt zirconium, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction.Separately
Outside, the outer surface of golden sample body 1 is additionally provided with the medicine layer 2 for auxiliary treatment and operation.
Wherein, lines 3 (lines 3 only marks sub-fraction in figure) is hemispherical and/or cylindric.In the present embodiment,
Hemispherical and/or columned lines 3 realizes preferable adhesion with the dense tissue in human body.
Above-mentioned a variety of lines 3 can be used targeted specifically according to different tissues, and effect is positioned with the detection for reaching optimal
Fruit.It should be noted that above-mentioned lines 3 may be designed as projection and may be designed in groove.The stability of convex shaped lines 3 is preferable,
And groove type lines 3 tissue is damaged it is smaller.
Distinguishingly, screw thread, the explosion type needle-like raised line that can be also rotated or intersect in the shell engraving of golden sample body 1, or
The needle-like raised line that person's axis is randomly distributed.
Embodiment six：
Cobalt zirconium gold mark implant provided by the utility model, including golden sample body 1.Specifically, golden sample body 1 is by metallic cobalt
Zirconium is made, and its profile is in capsule shape or cydariform, and its outer surface is provided with the lines 3 for increasing friction.Also, golden sample body
1 outer surface is additionally provided with the medicine layer 2 for auxiliary treatment and operation.In addition, the diameter range of golden sample body 1 is more than or equal to
0.1 millimeter, less than or equal to 1.5 millimeters；The length range of golden sample body 1 is more than or equal to 0.1 millimeter, less than or equal to 10 millimeters.Root
According to the data of Clinical practice, it is more applicable that golden sample body 1 is arranged to above appearance and size data, not only increases friction and improves
Stability, the injection implantation of golden sample body 1 is not influenceed also.
In the alternative of above-described embodiment, further, as shown in figure 5, medicine layer 2 is bonded by connecting oxidant layer 4
Onto golden sample body 1, the connection oxidant layer 4 is biological adhesive phase.In the present embodiment, due to the golden volume of sample body 1 itself compared with
It is small, by the mode operating difficulties such as spraying, inserting, and do not interfere with the property of medicine of medicine not only by bonding way, and can be with
Medicine dissolving is discharged in tissue；In addition, bond layer and medicine layer 2 are successively set outside golden sample body 1
Manufacturing mode has very high production efficiency.And bioadhesive has common splicing function and special biology doctor
Function is learned, safe to the human body, reliable, non-toxic, nothing three causes (carcinogenic, teratogenesis, mutagenesis), has good biocompatibility,
Do not stimulate and can gradually degrade, absorb and be metabolized.
Wherein, bioadhesive oxidant layer can select fibrinogen, fibrin ferment, muscle adhesive protein, casein, shell more
Sugar, chitosan, natural or modification of polysaccharides, polyethyleneglycol derivative or starch etc..
On the basis of above-mentioned cobalt zirconium gold mark implant, the utility model also provides a kind of gold mark implanted device.Such as Fig. 6 institutes
Show, gold mark implanted device includes sleeve pipe 5 and pushes pin 6.Wherein, sleeve pipe 5, which is socketed in, pushes pin outside 6, and the internal diameter of sleeve pipe 5 is more than above-mentioned cobalt
The cross-sectional diameter of zirconium gold mark implant, and less than twice of cross-sectional diameter.In addition, the shell of sleeve pipe 5 is provided with graduation mark
7, and the end of sleeve pipe 5 is tip shape.
Finally it should be noted that：Various embodiments above is only to illustrate the technical solution of the utility model, rather than it is limited
System；Although the utility model is described in detail with reference to foregoing embodiments, one of ordinary skill in the art should
Understand：It can still modify to the technical scheme described in foregoing embodiments, either to which part or whole
Technical characteristic carries out equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from this practicality newly
The scope of each embodiment technical scheme of type.
Claims (10)
- A kind of 1. cobalt zirconium gold mark implant, it is characterised in that including golden sample body, the golden sample body is made up of metallic cobalt zirconium, Its profile is in capsule shape or cydariform, and its outer surface is provided with the lines for increasing friction；The appearance of the golden sample body Face is additionally provided with medicine layer.
- 2. cobalt zirconium gold mark implant according to claim 1, it is characterised in that the gold mark body interior sets cavity, And side wall is provided with hollow out through hole；Medicament slow release case built in the cavity.
- 3. cobalt zirconium gold mark implant according to claim 1, it is characterised in that the lines is cross, T-shaped and/or V Shape.
- 4. cobalt zirconium according to claim 1 gold mark implant, it is characterised in that the lines be criss-cross, rhombus and/or Triangle.
- 5. cobalt zirconium gold mark implant according to claim 1, it is characterised in that the lines is hemispherical and/or cylinder Shape.
- 6. the cobalt zirconium gold mark implant according to any one of Claims 1 to 5, it is characterised in that the lines to be raised or Person's groove.
- 7. the cobalt zirconium gold mark implant according to any one of Claims 1 to 5, it is characterised in that the golden sample body is cross-section The diameter range in face is more than or equal to 0.1 millimeter, less than or equal to 1.5 millimeters；The length range of the golden sample body is more than or equal to 0.1 Millimeter, less than or equal to 10 millimeters.
- 8. the cobalt zirconium gold mark implant according to any one of Claims 1 to 5, it is characterised in that the medicine layer passes through company Oxidant layer is connect to be adhered on the golden sample body.
- 9. cobalt zirconium according to claim 8 gold mark implant, it is characterised in that the connection oxidant layer is made a living thing adhesive Layer.
- 10. a kind of gold mark implanted device, it is characterised in that including sleeve pipe and push pin；Described sleeve pipe is socketed in outer, the institute of pushing pin The internal diameter for stating sleeve pipe is more than the cross-sectional diameter of cobalt zirconium according to any one of claims 1 to 9 gold mark implant, and less than two The diameter in the cross section again, the shell of described sleeve pipe are provided with graduation mark, and the end of described sleeve pipe is tip shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720111271.3U CN207085090U (en) | 2017-02-06 | 2017-02-06 | A kind of cobalt zirconium gold mark implant and gold mark implanted device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720111271.3U CN207085090U (en) | 2017-02-06 | 2017-02-06 | A kind of cobalt zirconium gold mark implant and gold mark implanted device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207085090U true CN207085090U (en) | 2018-03-13 |
Family
ID=61547328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720111271.3U Active CN207085090U (en) | 2017-02-06 | 2017-02-06 | A kind of cobalt zirconium gold mark implant and gold mark implanted device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207085090U (en) |
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2017
- 2017-02-06 CN CN201720111271.3U patent/CN207085090U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230526 Address after: No. 35-8 Huishen Road, Xuefu Industrial Zone, Xiqing District, Tianjin, 300000 Patentee after: Zhongke Yingde (Tianjin) Health Industry Development Co.,Ltd. Address before: No. 241, Office Building, Former Hade Company Factory, Guanqitou Industrial Community, Donggang Street, Putuo District, Zhoushan City, Zhejiang Province, 316000 Patentee before: ZHEJIANG RONGCHENG MEDICAL TECHNOLOGY Co.,Ltd. |
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