CN206862885U - A kind of optical module of blood analyser - Google Patents
A kind of optical module of blood analyser Download PDFInfo
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- CN206862885U CN206862885U CN201720703243.0U CN201720703243U CN206862885U CN 206862885 U CN206862885 U CN 206862885U CN 201720703243 U CN201720703243 U CN 201720703243U CN 206862885 U CN206862885 U CN 206862885U
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- optical module
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Abstract
The utility model discloses a kind of optical module of blood analyser, including light source part, detection of particles part, optical module platform；The optical module platform offers short groove position and elongated slot position, and the light source part is arranged on the short groove position of optical module platform, and detection of particles part is separately mounted on optical module platform elongated slot position.Compared to existing optical module, the stronger scattering light for belonging to eosinophil is included in the special angle taken, can be only by detecting the collection for scattering light to differentiate this kind of particle in the case of without using additional agents.Meanwhile selected special angle scattering light can be sensed by photodiode, significantly reduce the cost of module.In addition, the utility model, by compact design, the fixing fabric structure of whole module, compared to existing optical module, there is great space advantage within A4 paper.And super large-scale scattering light can be detected, abundant particle data is obtained, improves the accuracy of particle classifying.
Description
Technical field
It the utility model is related to optical module, the light of especially a kind of blood analyser that particle is identified using light scattering method
Learn module.
Background technology
In clinical examination field or scientific research field, analyze composition and the counting of patient blood sample or body fluid, to diagnosis and
Analysis disease has great value.For example, the counting that blood analyser can generally be classified to haemocyte, wherein haemocyte
It is classified largely into red blood cell, leucocyte and blood platelet.
Different according to the principle counted to detection of particles, laser scattering method can be used in classification particle method.
Laser scattering method principle：Make light source with laser, beyond incident light direction, by means of detection scattered light intensity, frequency displacement and
Its angle rely on etc. and obtain the general designation of the method for the information such as particle weight, size, distribution and aggregated structure, have wide
Purposes.When the yardstick of scattering particles is much smaller than the wavelength of incident light（Such as scattering of the atmospheric molecule to visible ray）, claim molecule
Scattering or Rayleigh scattering, scattering light distribution is evenly and symmetrically.When the yardstick of scattering particles can compare with lambda1-wavelength（Example
Such as scattering of the floating dust particle to visible ray）, the intensity distribution for scattering light is asymmetric but complex distribution, referred to as Mie scattering.
Generally, the optical module using laser scattering method principle is as shown in Figure 7：The laser that semiconductor laser 101 is launched
Beam is focused in flow cell 103 after collimating mirror focus lens group 102, and leucocyte is out of flow cell 103 by the way that laser shines
Penetrate after leucocyte and produce the scattering light of all angles：Wherein forward scattering light blocking by diaphragm 104, selection need to be detected
Certain angle scope scattering light, then collimated lens 105 collimate after, be divided into two beam angle informations through speculum 106 with holes
Different light beams, detected respectively by detector 107 and 108；Side scattered light blocks by diaphragm 109, and selection needs to detect
Certain angle scope scattering light, then collimate by collimation lens 110, finally detected by detector 111.
The wherein scattering light of generally 1 degree to 6 degree or 1 degree to 3 degree of the detection of detector 107, it reflects cell volume
Size.The scattering light of generally 7 degree to 20 degree or 7 degree to 11 degree of the detection of detector 108, it reflects intracellular karyoplasmic ratio.
The scattering light of generally 60 degree to 120 degree or 70 degree to 110 degree of the detection of detector 111, its reacting cells kernel are complicated
Degree.Scatter diagram finally is drawn using the signal of each scattering light, can be by lymphocyte, monocyte, neutrophil cell, acidophilus
Property granulocyte and basophilic granulocyte distinguish.It is thin to be referred to as five classification blood with the blood cell analyzer of this Cleaning Principle
Born of the same parents' analyzer.
Although five kinds of leucocytes can be distinguished using above-mentioned optical module, because side scattered light is very faint, generally
Needing to use photomultiplier, it is higher by compared to the photodiode that forward scattering light uses, price as detection component
Decades of times.Meanwhile the side scattered light of the angular range can not be utilized exactly eosinophil at high proportion from neutrophilia
Distinguished in granulocyte.Moreover, the collimating mirror of detector front end also limit the volume size of whole optical module.
The content of the invention
The purpose of this utility model is in view of the shortcomings of the prior art, and to provide a kind of optical module of blood analyser,
By the cooperation of diaphragm and detector, the scattering light of special angle is detected, so as to exactly eosinophil at high proportion
Distinguished from neutrophil cell.
Realizing the technical scheme of the utility model purpose is：
A kind of optical module of blood analyser, including light source part, detection of particles part, optical module platform；It is described
Optical module platform offers short groove position and elongated slot position, and the light source part is arranged on the short groove position of optical module platform, grain
Sub- detection part is arranged on optical module platform elongated slot position.
The light source part, including semiconductor laser, collimation focusing lens group, light source part platform；The light source portion
Part platform vertical plane offers through hole, the transmitting optical axis and the central shaft weight of collimation focusing lens group of the semiconductor laser
Close, the transmitting optical axis of semiconductor laser is each attached to light source part platform vertical plane with the central shaft of collimation focusing lens group
On through hole.
The detection of particles part, including flow cell, detection of particles component platform, the first diaphragm, the first apertured bracket,
One detector, the second diaphragm, the second apertured bracket, the second detector, the first adjusting bracket, the second adjusting bracket；The flowing
Pond, the second adjusting bracket are installed on detection of particles component platform, first diaphragm, the first apertured bracket, the first detection
Device, the second diaphragm, the second apertured bracket, the second detector, the first adjusting bracket, the second adjusting bracket coordinate installation successively.
With flow cell center in angle of 45 degrees, the first detector can detect 22 to the first detector installation site simultaneously
Spend the scattering light to 68 degree.
The second detector installation site detects 2 degree and 10 simultaneously horizontal by 1 to 2 degree angle, the second detector
The specific scattering light of degree.
First diaphragm, the second diaphragm are used for mask stray light.
The light source part platform can front and rear regulation in the horizontal direction.
The detection of particles component platform can left and right adjusting in the horizontal direction.
The utility model compares existing optical module, and to belong to acidophil granules thin comprising stronger in the special angle taken
The scattering light of born of the same parents, can be only by detecting to differentiate this kind of grain in the case of without using additional agents to the collection for scattering light
Son.Meanwhile selected special angle scattering light can be sensed by photodiode, significantly reduce the cost of module.
In addition, the utility model, by compact design, the fixing fabric structure of whole module is within A4 paper, compared to existing optical mode
Block, there is great space advantage.And super large-scale scattering light can be detected, abundant particle data is obtained, improves particle point
The accuracy of class.
Brief description of the drawings
Fig. 1 is the overall structure diagram of embodiment；
Fig. 2 is light source part structural representation in Fig. 1；
Fig. 3 is the structural representation of detection of particles component platform and flow cell in Fig. 1；
Fig. 4 is the structural representation of detection of particles Microwave Limb Sounder in Fig. 1；
Fig. 5 is the second detector angle schematic diagram in Fig. 4；
Fig. 6 is the first detector angle schematic diagram in Fig. 4；
Fig. 7 is the laser scattering method principle optical module figure of prior art.
In figure, the semiconductor laser of 301. light source part, 302. detection of particles part, 303. optical module platform 401.
The detection of particles component platform 203. first of 402. light source part platform, 403. collimation focusing lens group, 103. flow cell 501.
The apertured bracket 202. second of 201. second diaphragm of diaphragm 502. first apertured bracket, 204. first detector 503. second is visited
Survey the adjusting bracket of 504. first adjusting bracket of device 505. second.
Embodiment
Content of the present utility model is further elaborated with reference to embodiment and accompanying drawing, but is not new to this practicality
The restriction of type.
Embodiment：
Reference picture 1, a kind of optical module of blood analyser, including light source part 301, detection of particles part 302, optics
Modular platform 303；The optical module platform 303 offers short groove position and elongated slot position, and the light source part 301 is arranged on optics
On the short groove position of modular platform 303, detection of particles part 302 is arranged on the elongated slot position of optical module platform 303.
Reference picture 2, the light source part 301, including semiconductor laser 401, collimation focusing lens group 403, light source portion
Part platform 402；The vertical plane of light source part platform 402 offers through hole, the transmitting optical axis of the semiconductor laser 401 with
The center overlapping of axles of collimation focusing lens group 403, transmitting optical axis and the collimation focusing lens group 403 of semiconductor laser 401
Central shaft is each attached on the through hole of the vertical plane of light source part platform 402.The light source part platform 402 can in the horizontal direction before
After adjust.
Reference picture 3-4, the detection of particles part 302, including flow cell 103, detection of particles component platform 501, first
Diaphragm 203, the first apertured bracket 502, the first detector 204, the second diaphragm 201, the second apertured bracket 503, the second detector
202nd, the first adjusting bracket 504, the second adjusting bracket 505；The flow cell 103, the second adjusting bracket 505 are installed in particle
On detection part platform 501, first diaphragm 203, the first apertured bracket 502, the first detector 204, the second diaphragm 201,
Second apertured bracket 503, the second detector 202, the first adjusting bracket 504, the second adjusting bracket 505 coordinate installation successively.Institute
State the first diaphragm 203, the second diaphragm 201 is used for mask stray light.The detection of particles component platform 501 can be left in the horizontal direction
Right regulation.
Reference picture 5, the installation site of the second detector 202 are same horizontal by 1 to 2 degree angle, the second detector 202
When detection 2 degree and 10 degree specifically scatter light.
Reference picture 6, the installation site of the first detector 204 and the center of flow cell 103 in angle of 45 degrees, the first detector
204 can detect 22 degree to 68 degree of scattering light simultaneously.
Using the optical module, after semiconductor laser 401 is started working, the collimated focus lens group 403 of light beam, shaping
Into the hot spot of given shape size, and focus on the center of flow cell 103.Now particle is in the presence of specific liquid-way system,
By the center of flow cell 103, and the laser facula irradiation being focused, so as to produce scattering in the range of whole space multistory
Light.Then, the first diaphragm 203 is arranged in the approach of scattering light propagation, and it acts on the scattering light for being to allow special angle and led to
Cross, and the first detector 204 for being placed on the dead astern of the first diaphragm 203 receives.Similarly, the second diaphragm 201 is also disposed in
In the approach for scattering light propagation, it is to allow the scattering light of special angle by and after being placed on the second diaphragm 201 just that it, which is acted on,
Second detector 202 of side receives.Second detector 202 and the first detector 204 scatter receive three special angles
Light is converted into electric signal, for the species of network analysis identification particle.
Claims (8)
- A kind of 1. optical module of blood analyser, it is characterised in that：Including light source part (301), detection of particles part (302), optical module platform (303)；The optical module platform (303) offers short groove position and elongated slot position, the light source portion Part (301) is arranged on optical module platform（303）Short groove position on, detection of particles part (302) is arranged on optical module platform （303）On elongated slot position.
- 2. the optical module of blood analyser as claimed in claim 1, it is characterised in that：The light source part（301）, including Semiconductor laser（401）, collimation focusing lens group（403）, light source part platform（402）；The light source part platform（402） Vertical plane be provided with through hole, the semiconductor laser（401）Transmitting optical axis and collimation focusing lens group（403）Center Overlapping of axles, semiconductor laser（401）Transmitting optical axis and collimation focusing lens group（403）Central shaft be each attached to light source portion Part platform（402）On the through hole of vertical plane.
- 3. the optical module of blood analyser as claimed in claim 1, it is characterised in that：The detection of particles part（302）, Including flow cell（103）, detection of particles component platform（501）, the first diaphragm（203）, the first apertured bracket（502）, first visit Survey device（204）, the second diaphragm（201）, the second apertured bracket（503）, the second detector（202）, the first adjusting bracket（504）、 Second adjusting bracket（505）；The flow cell（103）, the second adjusting bracket（505）It is installed in detection of particles component platform （501）On, first diaphragm（203）, the first apertured bracket（502）, the first detector（204）, the second diaphragm（201）, Two apertured brackets（503）, the second detector（202）, the first adjusting bracket（504）, the second adjusting bracket（505）Coordinate peace successively Dress.
- 4. the optical module of blood analyser as claimed in claim 3, it is characterised in that：First detector（204）Peace Holding position and flow cell（103）Center in angle of 45 degrees, the first detector（204）22 degree to 68 degree of scattering light can be detected.
- 5. the optical module of blood analyser as claimed in claim 3, it is characterised in that：Second detector（202）Peace Holding position is horizontal by 1 to 2 degree angle, the second detector（202）2 degree and 10 degree specific scattering light can be detected simultaneously.
- 6. the optical module of blood analyser as claimed in claim 3, it is characterised in that：First diaphragm（203）, second Diaphragm（201）For mask stray light.
- 7. the optical module of blood analyser as claimed in claim 2, it is characterised in that：The light source part platform（402） Can front and rear regulation in the horizontal direction.
- 8. the optical module of blood analyser as claimed in claim 3, it is characterised in that：The detection of particles component platform （501）Can left and right adjusting in the horizontal direction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720703243.0U CN206862885U (en) | 2017-06-16 | 2017-06-16 | A kind of optical module of blood analyser |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720703243.0U CN206862885U (en) | 2017-06-16 | 2017-06-16 | A kind of optical module of blood analyser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206862885U true CN206862885U (en) | 2018-01-09 |
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ID=60826539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720703243.0U Ceased CN206862885U (en) | 2017-06-16 | 2017-06-16 | A kind of optical module of blood analyser |
Country Status (1)
| Country | Link |
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| CN (1) | CN206862885U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110967316A (en) * | 2018-09-30 | 2020-04-07 | 深圳市帝迈生物技术有限公司 | Blood analysis equipment and optical detection device thereof |
| CN113196039A (en) * | 2019-01-14 | 2021-07-30 | 深圳迈瑞生物医疗电子股份有限公司 | Sample optical detection device, sample detection method and sample analyzer |
-
2017
- 2017-06-16 CN CN201720703243.0U patent/CN206862885U/en not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110967316A (en) * | 2018-09-30 | 2020-04-07 | 深圳市帝迈生物技术有限公司 | Blood analysis equipment and optical detection device thereof |
| CN113196039A (en) * | 2019-01-14 | 2021-07-30 | 深圳迈瑞生物医疗电子股份有限公司 | Sample optical detection device, sample detection method and sample analyzer |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| IW01 | Full invalidation of patent right |
Decision date of declaring invalidation: 20181206 Decision number of declaring invalidation: 38167 Granted publication date: 20180109 |
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| IW01 | Full invalidation of patent right |