CN206990445U - Blood analysis device - Google Patents
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- CN206990445U CN206990445U CN201720678582.8U CN201720678582U CN206990445U CN 206990445 U CN206990445 U CN 206990445U CN 201720678582 U CN201720678582 U CN 201720678582U CN 206990445 U CN206990445 U CN 206990445U
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Abstract
A kind of blood analysis device is the utility model is related to, is analyzed using the laser haemocyte indoor to flowing.Blood analysis device includes collimation focusing lens group, collecting lens and probe assembly, collimation focusing lens group is used for laser alignment and focuses on detection zone, collecting lens is used to collect the scattering light being emitted by flow chamber, and probe assembly is used to collect the scattering light being emitted by collecting lens.The distance at the principal point of collecting lens and the center of detection zone is L, and L scope is d ＜ L≤f (D, α).By the distance for adjusting the principal point of collecting lens and the center of detection zone, so that outer surface of the principal point of collecting lens away from flow chamber, it may be such that the object distance increase of collecting lens, the picture point of collecting lens just can be close to flow chamber direction, enter the size reduction for causing whole scattering light collecting system, so as to effectively reduce the space-consuming of scattering light collecting system.
Description
Technical field
The technical field of blood analysis is the utility model is related to, more particularly to a kind of blood analysis device.
Background technology
Five classification cellanalyzers are generally used for analyzing the leucocyte in blood, and leucocyte is divided into lymph
Cell, monocyte, neutrophil leucocyte, eosinophil and the class of basophilic granulocyte five.Five classification cellanalyzers one
As leucocyte is classified using laser technology combination fluorescent labelling techniques.Its principle is：Irradiated using laser as light source
By fluorescence labeling handle cell sample when, forward scattering light, side scattered light and lateral fluorescence, forward scattering light can be produced
Leucocyte volume size, the situation of cell inclusion (nucleus and particle situation) can be reflected with side scattered light, laterally
Fluorescence can then reflect the content of intracellular DNA (DNA) and ribonucleic acid (RNA).Forward scattering light, laterally dissipate
Penetrating light and lateral fluorescence, device collection can change into electric signal after testing, and analysis electric signal can carry out five classification to leucocyte.
The classification cellanalyzer of in general five, it scatters light collecting system, and (lateral scattering light collecting system or forward direction dissipate
Penetrate light collecting system) include more optical component, after the assembling of numerous optical components, scatter the size of light collecting system
It is longer.
Utility model content
Based on this, it is necessary to scatter asking for the longer dimension of light collecting system for the classification cellanalyzer of in general five
A kind of topic, there is provided blood analysis device.
A kind of blood analysis device, analyzed using the laser haemocyte indoor to flowing, the blood analysis device
Including：
Collimation focusing lens group, positioned at the side of the flow chamber, the collimation focusing lens group has primary optic axis, institute
State primary optic axis to extend in a first direction, and the primary optic axis passes through the detection zone of the flow chamber；The collimation focusing is saturating
Microscope group is used for laser alignment and focuses on the detection zone；
Collecting lens, positioned at the opposite side of the flow chamber, the collecting lens has the second optical axis, second optical axis
Through the detection zone；The collecting lens is used to collect the scattering light being emitted by the flow chamber；And
Probe assembly, the same side of the flow chamber is located at the collecting lens, and the collecting lens is positioned at described
Between probe assembly and the flow chamber；The probe assembly is used to collect the scattering light being emitted by the collecting lens；
The principal point of the collecting lens and the distance at the center of the detection zone are L, and L scope is d ＜ L≤f (D, α)；
Wherein, D is effective clear aperature of the collecting lens, and α is the collection half-angle of the scattering light, and f (D, α) is D and α letter
Number, d are the distance at the center and the outer surface of the flow chamber of the detection zone.
In one of the embodiments, the principal point of the collecting lens with the distance L at the center of the detection zone by following
Formula represents：
F (D, α)=(D- δ)/(2*tan α)
Wherein, δ is the regulation tolerance of the collecting lens.
In one of the embodiments, D unit is millimeter, and the regulation tolerance δ of collecting lens scope is 0.5 milli
Rice~1.0 millimeters.
In one of the embodiments, second optical axis extends in a second direction, the collecting lens be used for collect by
The side scattered light and lateral fluorescence of the flow chamber outgoing.
In one of the embodiments, the collecting lens is spherical lens group, and the numerical aperture of the collecting lens is big
In 0.39.
In one of the embodiments, the collecting lens is non-spherical lens, and the numerical aperture of the collecting lens is big
In 0.39, the focal length of the collecting lens is 2.5 millimeters~6.0 millimeters.
In one of the embodiments, the probe assembly includes dichroscope, the first detection module and the second detection mould
Group, the dichroscope, the first detection module and the second detection module are located at the same side of the flow chamber, and institute
Dichroscope is stated between the described first detection module and the collecting lens；The dichroscope is used to separate lateral scattering
Light and lateral fluorescence, the first detection module are used to collect the lateral fluorescence being emitted by the dichroscope, and described second visits
Module is surveyed to be used to collect the side scattered light being emitted by the dichroscope.
In one of the embodiments, the second detection module includes side astigmatism door screen and side dissipates detector, and the side dissipates
Waist-shaped hole is offered on diaphragm, the side astigmatism door screen is used to filter the side scattered light being emitted by the dichroscope, the side
Detector is dissipated to be used to receive by the side scattered light of side astigmatism door screen filtering.
In one of the embodiments, second optical axis extends along the first direction, and the collecting lens is used to receive
Collect the forward scattering light being emitted by the flow chamber.
In one of the embodiments, the collecting lens is spherical lens group, and the numerical aperture of the collecting lens is big
In 0.17.
In one of the embodiments, the probe assembly has axis, the axis and second optical axis
Angle is 5 degree~30 degree.
In one of the embodiments, the axis and the angle of second optical axis are 5 degree~10 degree.
Above-mentioned blood analysis device, on laser light incident to collimation focusing lens group, collimated focus lens group collimationization is simultaneously
The detection zone of flow chamber is focused on, laser is exposed in detection zone on cell to be measured, you can produce forward scattering light, laterally dissipate
Penetrate light and lateral fluorescence.When collecting lens is in the light path of side scattered light, side scattered light and lateral fluorescence are by flowing
After room is emitted to collecting lens, is collected by collecting lens and be emitted to probe assembly, probe assembly can by side scattered light and
Lateral fluorescence is converted to electric signal to analyze haemocyte by optical signal.When the principal point of collecting lens and the center of detection zone
Distance L when being in the range of d ＜ L≤f (D, α), by adjusting the distance of the principal point of collecting lens and the center of detection zone,
So that outer surface of the principal point of collecting lens away from flow chamber, you can so that the object distance increase of collecting lens, the picture of collecting lens
Point just can be close to flow chamber direction, enters to cause the size reduction of whole lateral scattering light collecting system, so as to effective
The space-consuming of lateral scattering light collecting system is reduced, and reduces the manufacturing cost of five classification cellanalyzers.Similarly, receipts are worked as
Collection lens are when being in the light path of forward scattering light, at the principal point of collecting lens and the distance L at the center of detection zone
In the range of d ＜ L≤f (D, α), the space-consuming of forward scattering light collecting system equally can be effectively reduced, and reduce by five
The manufacturing cost of classification cellanalyzer.
Brief description of the drawings
Fig. 1 is the top view of blood analysis device in an embodiment；
Fig. 2 is the front view of blood analysis device shown in Fig. 1；
Fig. 3 is the object-image relation figure of blood analysis device shown in Fig. 1.
Embodiment
For the ease of understanding the utility model, the utility model is more fully retouched below with reference to relevant drawings
State.Preferred embodiment of the present utility model is given in accompanying drawing.But the utility model can come in many different forms
Realize, however it is not limited to embodiment described herein.On the contrary, the purpose for providing these embodiments is made to of the present utility model
The understanding of disclosure more thorough and comprehensive.
It should be noted that when element is referred to as " being fixed on " another element, it can be directly on another element
Or there may also be element placed in the middle.When an element is considered as " connection " another element, it can be directly connected to
To another element or it may be simultaneously present centering elements.Term as used herein " vertical ", " horizontal ", " left side ",
" right side " and similar statement are for illustrative purposes only.
Unless otherwise defined, all of technologies and scientific terms used here by the article is led with belonging to technology of the present utility model
The implication that the technical staff in domain is generally understood that is identical.It is simply in term used in the description of the present utility model herein
The purpose of description specific embodiment, it is not intended that in limitation the utility model.Term as used herein " and/or " include
The arbitrary and all combination of one or more related Listed Items.
With reference to figure 1 and Fig. 2, in one embodiment, blood analysis device is entered using laser to the haemocyte in flow chamber 10
Row analysis.The blood analysis device includes collimation focusing lens group 200, collecting lens and probe assembly.In embodiment illustrated in fig. 1
In, using horizontal direction as first direction, using vertical direction as second direction.Collimation focusing lens group 200 is located at flow chamber 10
Side, collimation focusing lens group 200 have primary optic axis, and primary optic axis extends in a first direction, and primary optic axis passes through flowing
The detection zone of room 10.In one embodiment, collimation focusing lens group 200 includes collimation lens 210, the first cylindrical mirror 220 and the
Two cylindrical mirrors 230, collimation lens 210, the first cylindrical mirror 220 and the second cylindrical mirror 230 are arranged successively from left to right.Implement one
In example, using the optical axis of collimation lens 210 as primary optic axis, the optical axis of the optical axis of the first cylindrical mirror 220 and the second cylindrical mirror 230
It is consistent with the bearing of trend of primary optic axis.Further, in one embodiment, the optical axis and the second cylinder of the first cylindrical mirror 220
The optical axis of mirror 230 overlaps with primary optic axis.In one embodiment, blood analysis device can also include laser 30.Laser
When the laser that device 30 is emitted is propagated in the first direction, collimated light beam is can be changed to after collimated lens 210, collimated light beam passes through successively
Cross the first cylindrical mirror 220 and the second cylindrical mirror 230, you can focus on the center (i.e. detection zone) of flow chamber 10.
In one embodiment, collecting lens is in lateral scattering light path, i.e., collecting lens now is saturating for lateral collection
Mirror 400, lateral collection lens 400 are located at the opposite side of flow chamber 10.In one embodiment, second direction is vertical direction, side
It is non-spherical lens to collecting lens 400, the second optical axis is the optical axis of lateral collection lens 400, and the second optical axis edge is vertical square
To extension, and the second optical axis passes through detection zone.Lateral collection lens 400 are used to collect the side scattered light being emitted by flow chamber 10
With lateral fluorescence.Corresponding with lateral collection lens 400, now, probe assembly is lateral probe assembly 500.Lateral detection group
Part 500 is located at the same side of flow chamber 10 with lateral collection lens 400, and lateral collection lens 400 are located at lateral probe assembly
Between 500 and flow chamber 10.Lateral probe assembly 500 be used to collecting the side scattered light that is emitted by lateral collection lens 400 or
Lateral fluorescence.Side scattered light or lateral fluorescence are after lateral probe assembly 500, you can electric signal is converted into by optical signal,
By analyzing electric signal, you can the haemocyte in blood is analyzed.
With reference to Fig. 3, the haemocyte in detection zone is abstracted into object point o, from the image formula of convex lens,
When object point o positions are constant, adjustment lateral collection lens 400 and object point o distance causes lateral collection lens 400 away from object point o
(increasing object distance), that is, lateral collection lens 400 are caused to be moved to position a' by position a, the picture point of lateral collection lens 400 is
Position b' can be moved to by position b, that is, make it that picture point is close to detection zone.Because the optical signal of picture point uses lateral probe assembly
500 are received, therefore during increase object distance, can reduce the distance of lateral probe assembly 500 and flow chamber 10, so as to shorten
The length of lateral scattering light collecting system.
In one embodiment, in the principal point (intersection point of optical axis and object space interarea) and detection zone of lateral collection lens 400
The distance of the heart is L (i.e. object distance), and L scope is d ＜ L≤f (D, α).Wherein, D is effective light hole of lateral collection lens 400
Footpath, α are the collection half-angle of side scattered light, and f (D, α) is D and α function, and d is appearance of the center with flow chamber 10 of detection zone
The distance in face.Further, in one embodiment, the distance L at the center of the principal point of lateral collection lens 400 and detection zone is by following
Formula represents：
F (D, α)=(D- δ)/(2*tan α)
Wherein, δ is the regulation tolerance of lateral collection lens 400, and δ is identical with D, L unit.Regulation tolerance δ's acts on
In it allows the cylindrical effective with lateral collection lens 400 of the hot spot that side scattered light projects on lateral collection lens 400
Clear aperature formed it is cylindrical between gap be present, to cause hot spot that side scattered light projects on lateral collection lens 400
It can fall completely within effective clear aperature of lateral collection lens 400, so as to ensure the reception of side scattered light.Implement one
In example, when D, L unit are millimeter, the regulation tolerance δ of lateral collection lens 400 scope is 0~1.0 millimeter.It is real one
Apply in example, δ values are 0, and the distance L spans at the principal point of lateral collection lens 400 and the center of detection zone are d ＜ L≤(D/
(2*tanα)).When L values are (D/ (2*tan α)), i.e., when object distance takes maximum, the length of lateral scattering light collecting system is most
It is small.Further, in one embodiment, the regulation tolerance δ of lateral collection lens 400 span is 0.5 millimeter~1.0 millis
Rice, the i.e. span of the L upper limit are at ((D-1)/(2*tan α)) between ((D-0.5)/(2*tan α)).At the L upper limit
When in the range of this, be advantageous to the regulation of optical system and the design of mechanical structure.In one embodiment, lateral collection lens
400 focal length is 4.0136 millimeters, and effective clear aperature is 5.1 millimeters, when object distance increase by 2.66%, the lateral chi of optical system
It is very little to reduce 46.65%, while effective collection of side scattered light can be ensured.
It is understood that when collecting lens is in preceding in light path, i.e., collecting lens for it is preceding to collecting lens 600 when,
The principal point of forward direction collecting lens 600 is same with the distance L at the center of detection zone to be may be in the range of d ＜ L≤f (D, α), this
When, D is preceding effective clear aperature to collecting lens 600, and α is the collection half-angle of forward scattering light.Lateral collection lens 400
The design of the distance L at the center of principal point and detection zone design formula and the regulation tolerance of lateral collection lens 400 is equally applicable
In forward direction light path, here is omitted.
Above-mentioned blood analysis device, on laser light incident to collimation focusing lens group 200, collimated focus lens group 200 is accurate
Straightization and the detection zone for focusing on flow chamber 10, laser are exposed in detection zone on cell to be measured, you can produce forward scattering
Light, side scattered light and lateral fluorescence.When collecting lens is in the light path of side scattered light, side scattered light and lateral glimmering
After light is emitted to collecting lens by flow chamber 10, is collected by collecting lens and be emitted to probe assembly, probe assembly can be by side
Electric signal is converted to analyze haemocyte by optical signal to scattering light and lateral fluorescence.Principal point and inspection when collecting lens
When surveying the distance L at the center in area and being in the range of d ＜ L≤f (D, α), by the principal point and detection zone that adjust collecting lens
The distance at center so that outer surface of the principal point of collecting lens away from flow chamber 10, you can so that the object distance increase of collecting lens,
The picture point of collecting lens just can be close to the direction of flow chamber 10, enters to cause the size contracting of whole lateral scattering light collecting system
It is small, so as to effectively reduce the space-consuming of lateral scattering light collecting system, and reduce the system of five classification cellanalyzers
Cause this.Similarly, when collecting lens is in the light path of forward scattering light, the principal point and detection zone of collecting lens are passed through
The distance L at center be in the range of d ＜ L≤f (D, α), equally can effectively reduce accounting for for forward scattering light collecting system
With space, and reduce the manufacturing cost of five classification cellanalyzers.
In lateral collection lens 400 in the embodiment of non-spherical lens, the numerical aperture of lateral collection lens 400 is more than
0.39, the focal length of lateral collection lens 400 is 2.5 millimeters~6.0 millimeters.When the numerical aperture of lateral collection lens 400 takes
Value and the value of focal length within the above range when, advantageously ensure that lateral collection lens 400 to side scattered light and lateral glimmering
The reception of light.In another embodiment, lateral collection lens 400 are spherical lens group, the numerical aperture of lateral collection lens 400
More than 0.39.When spherical lens group numerical aperture value within the above range when, be equally beneficial for ensure lateral collection it is saturating
Reception of the mirror 400 to side scattered light and lateral fluorescence.Because the price of spherical lens group is generally below non-spherical lens, use
Spherical lens group also helps the cost for the optical component for reducing blood analysis device as lateral collection lens 400.
With reference to figure 1, in one embodiment, lateral probe assembly 500 includes dichroscope 510, first and detects the and of module 520
Second detection module 530, dichroscope 510, first detect the detection module 530 of module 520 and second and are located at the same of flow chamber 10
Side, and dichroscope 510 is between the first detection module 520 and lateral collection lens 400.Dichroscope 510 is used to divide
From side scattered light and lateral fluorescence, the first detection module 520 is used to collect the lateral fluorescence being emitted by dichroscope 510, the
Two detection modules 530 are used to collect the side scattered light being emitted by dichroscope 510.
Specifically, in one embodiment, the first detection module 520 includes aperture 521, optical filter 523 and fluorescence spy
Survey device 525.Aperture 521, optical filter 523 and fluorescent probe 525 are arranged successively in a second direction, aperture 521
In close to the side of dichroscope 510.The side scattered light and lateral fluorescence being emitted by flow chamber 10 are saturating first by lateral collection
Mirror 400 is collected, and is then emitted on dichroscope 510.Dichroscope 510 separates side scattered light and lateral fluorescence, laterally
Scattering light is then emitted to aperture 521 through dichroscope 510.Light through aperture 521 continues to be emitted to filter
Mating plate 523, side scattered light can further be filtered by optical filter 523, lateral fluorescence then can smoothly pass through optical filter
523.The lateral fluorescence being emitted by optical filter 523 is then emitted on fluorescent probe 525, and fluorescent probe 525 can be by light
Signal is converted into electric signal.
In one embodiment, the second detection module 530 includes side astigmatism door screen 531 and side dissipates detector 533, side astigmatism door screen
531 between dichroscope 510 and side dissipate detector 533.The side scattered light separated by dichroscope 510 is through dichroscope
510 reflex on side astigmatism door screen 531, and astigmatism 531 pairs of side scattered lights of door screen in side filter, through the light of side astigmatism door screen 531
Continue to be emitted on the scattered detector 533 in side, side, which dissipates detector 533, to be converted into electric signal by optical signal by side scattered light.
In one embodiment, waist-shaped hole (not shown) is offered on side astigmatism door screen 531, waist-shaped hole is used to filter to be gone out by dichroscope 510
Veiling glare in the side scattered light that the side scattered light penetrated, i.e. waist-shaped hole will can be emitted by dichroscope 510 masks.Waist
The effect of type hole also resides in, and it can reduce the debugging difficulty of lateral scattering optical receiver system.
It is preceding into the embodiment of collecting lens 600 in collecting lens, the second optical axis is the preceding light to collecting lens 600
Axle, the second optical axis extend in a first direction, and forward direction collecting lens 600 is used to collect the forward scattering light being emitted by flow chamber 10,
Now, probe assembly is forward detection component 700.Specifically, in one embodiment, forward direction collecting lens 600 is spherical lens
Group, the numerical aperture of forward direction collecting lens 600 are more than 0.17.When spherical lens group numerical aperture value within the above range
When, effective collection before advantageously ensuring that to collecting lens 600 to forward scattering light, and can also be reduced using non-spherical lens
The cost of optics.In other embodiments, forward direction collecting lens 600 can also use non-spherical lens, when using non-
During spherical lens, effective collection before can equally ensureing to collecting lens 600 to forward scattering light.
With reference to figure 1, in forward direction collecting lens 600 in the embodiment of spherical lens group, forward direction collecting lens 600 includes flat
Convex lens 610 and biconvex lens 620, planoconvex spotlight 610 is between flow chamber 10 and biconvex lens 620, biconvex lens 620
Between planoconvex spotlight 610 and forward detection component 700.In one embodiment, the optical axis of planoconvex spotlight 610 is the second light
Axle, the direction extension of the optical axis of biconvex lens 620 along the second optical axis.Further, in one embodiment, the light of planoconvex spotlight 610
The optical axis coincidence of axle and biconvex lens 620.In one embodiment, blood analysis device can also include gear direct projection diaphragm 800, gear
Direct projection diaphragm 800 is positioned at preceding between collecting lens 600 and flow chamber 10.The forward scattering light being emitted by flow chamber 10, through gear
After direct projection diaphragm 800 filters, to collecting lens 600 before being emitted to, after the preceding collection to collecting lens 600, to spy before being emitted to
Survey component 700.Gear direct projection diaphragm 800 is used to filter the DC quantity in forward scattering light, and forward detection component is emitted to weaken
The energy of 700 light, prevent current saturation caused by forward detection component 700.In one embodiment, forward detection component
700 include preceding astigmatism door screen 710 and preceding scattered detector 720, and preceding astigmatism door screen 710 is positioned at preceding to collecting lens 600 and preceding scattered detector
Between 720.Aperture is offered on preceding astigmatism door screen 710, the light being emitted by forward direction collecting lens 600 can be filtered by aperture,
Preceding scattered detector 720 receives the light by the filtering of preceding astigmatism door screen 710 and converts optical signal into electric signal.
With reference to figure 1 and Fig. 2, in one embodiment, forward detection component 700 has axis 730, axis 730 and
The angle of two optical axises is 5 degree~30 degree.Further, in one embodiment, the axis 730 and second of forward detection component 700
The angle of optical axis is 5 degree~10 degree.By the way that forward detection component 700 is tilted into installation so that the axis of forward detection component 700
The angle of the optical axis of line 730 and second within the above range when, it is secondary can to prevent that the light for entering preceding scattered detector 720 from occurring
Reflection scattered detector 720 before being again introduced into.Installed by the inclination of forward detection device 700, can be by the light of secondary reflection
Energy barrier fall, to avoid the light of secondary reflection from dissipating detector 720 before entering, the light that scattered detector 720 receives before causing
The energy of signal is unstable.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality
Apply all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, the scope that this specification is recorded all is considered to be.
Embodiment described above only expresses several embodiments of the present utility model, and its description is more specific and detailed,
But therefore it can not be interpreted as the limitation to utility model patent scope.It should be pointed out that the common skill for this area
For art personnel, without departing from the concept of the premise utility, various modifications and improvements can be made, these are belonged to
The scope of protection of the utility model.Therefore, the protection domain of the utility model patent should be determined by the appended claims.
Claims (12)
1. a kind of blood analysis device, analyzed using the laser haemocyte indoor to flowing, it is characterised in that the blood
Analytical equipment includes：
Collimation focusing lens group, positioned at the side of the flow chamber, the collimation focusing lens group has a primary optic axis, and described
One optical axis extends in a first direction, and the primary optic axis passes through the detection zone of the flow chamber；The collimation focusing lens group
For by laser alignment and focusing on the detection zone；
Collecting lens, positioned at the opposite side of the flow chamber, the collecting lens has the second optical axis, and second optical axis passes through
The detection zone；The collecting lens is used to collect the scattering light being emitted by the flow chamber；And
Probe assembly, the same side of the flow chamber is located at the collecting lens, and the collecting lens is located at the detection
Between component and the flow chamber；The probe assembly is used to collect the scattering light being emitted by the collecting lens；
The principal point of the collecting lens and the distance at the center of the detection zone are L, and L scope is d ＜ L≤f (D, α)；Wherein,
D is effective clear aperature of the collecting lens, and α is the collection half-angle of the scattering light, and f (D, α) is D and α function, and d is
The distance at the center of the detection zone and the outer surface of the flow chamber.
2. blood analysis device according to claim 1, it is characterised in that the principal point of the collecting lens and the detection
The distance L at the center in area is represented by below equation：
F (D, α)=(D- δ)/(2*tan α)
Wherein, δ is the regulation tolerance of the collecting lens.
3. blood analysis device according to claim 2, it is characterised in that D unit is millimeter, the collecting lens
The scope for adjusting tolerance δ is 0.5 millimeter~1.0 millimeters.
4. according to the blood analysis device described in claims 1 to 3 any one, it is characterised in that second optical axis is along
Two directions extend, and the collecting lens is used to collect the side scattered light being emitted by the flow chamber and lateral fluorescence.
5. blood analysis device according to claim 4, it is characterised in that the collecting lens is spherical lens group, institute
The numerical aperture for stating collecting lens is more than 0.39.
6. blood analysis device according to claim 4, it is characterised in that the collecting lens is non-spherical lens, institute
The numerical aperture for stating collecting lens is more than 0.39, and the focal length of the collecting lens is 2.5 millimeters~6.0 millimeters.
7. blood analysis device according to claim 4, it is characterised in that the probe assembly includes dichroscope, the
One detection module and the second detection module, the dichroscope, the first detection module and the second detection module are located at
The same side of the flow chamber, and the dichroscope is between the described first detection module and the collecting lens；It is described
Dichroscope is used to separate side scattered light and lateral fluorescence, and the first detection module is used to collect to be gone out by the dichroscope
The lateral fluorescence penetrated, the second detection module are used to collect the side scattered light being emitted by the dichroscope.
8. blood analysis device according to claim 7, it is characterised in that the second detection module includes side astigmatism door screen
Detector is dissipated with side, waist-shaped hole is offered on the side astigmatism door screen, the side astigmatism door screen is used to filter to be gone out by the dichroscope
The side scattered light penetrated, the side dissipate detector and are used to receive by the side scattered light of side astigmatism door screen filtering.
9. according to the blood analysis device described in claims 1 to 3 any one, it is characterised in that second optical axis is along institute
First direction extension is stated, the collecting lens is used to collect the forward scattering light being emitted by the flow chamber.
10. blood analysis device according to claim 9, it is characterised in that the collecting lens is spherical lens group, institute
The numerical aperture for stating collecting lens is more than 0.17.
11. blood analysis device according to claim 9, it is characterised in that the probe assembly has axis, described
Axis and the angle of second optical axis are 5 degree~30 degree.
12. blood analysis device according to claim 11, it is characterised in that the axis and second optical axis
Angle is 5 degree~10 degree.
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| WO2021196131A1 (en) * | 2020-04-02 | 2021-10-07 | 深圳迈瑞生物医疗电子股份有限公司 | Optical detection system for analyzing blood cells and blood cell analyzer |
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| WO2020147255A1 (en) * | 2019-01-14 | 2020-07-23 | 深圳迈瑞生物医疗电子股份有限公司 | Sample optical detection device, sample detection method, and sample analyzer |
| CN113196039A (en) * | 2019-01-14 | 2021-07-30 | 深圳迈瑞生物医疗电子股份有限公司 | Sample optical detection device, sample detection method and sample analyzer |
| WO2021196131A1 (en) * | 2020-04-02 | 2021-10-07 | 深圳迈瑞生物医疗电子股份有限公司 | Optical detection system for analyzing blood cells and blood cell analyzer |
| CN116087067A (en) * | 2023-04-07 | 2023-05-09 | 深圳市帝迈生物技术有限公司 | Optical flow cytometer for blood cell characterization |
| CN116087067B (en) * | 2023-04-07 | 2023-12-29 | 深圳市帝迈生物技术有限公司 | Optical flow cytometer for blood cell characterization |
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Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of utility model: blood analysis device Granted publication date: 20180209 License type: Common License Record date: 20220804 |