CN206435557U - Reaction cup cleaning device and sample analyser - Google Patents

Reaction cup cleaning device and sample analyser Download PDF

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Publication number
CN206435557U
CN206435557U CN201621030476.0U CN201621030476U CN206435557U CN 206435557 U CN206435557 U CN 206435557U CN 201621030476 U CN201621030476 U CN 201621030476U CN 206435557 U CN206435557 U CN 206435557U
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China
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reaction cup
magnet
cleaning
needle
cleaning device
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CN201621030476.0U
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Chinese (zh)
Inventor
王浩
李�浩
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Maccura Medical Electronics Co Ltd
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SICHUAN MAKER BIOMEDICAL ELECTRONIC Co Ltd
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Abstract

The utility model discloses a kind of reaction cup cleaning device and sample analyser, reaction cup cleaning device includes:Mounting bracket, reaction cup disk, wiper mechanism, the elevating mechanism of driving wiper mechanism lifting is installed on the driving part that mounting bracket and driving reaction cup disk are rotated;Wherein, reaction cup disk, which is provided with, is used for the putting hole of placing response cup;Wiper mechanism includes:Needle assemblies, for clean liquid pumping needle wash pin pond and cleaning drive mechanism;Needle assemblies include liquid pumping needle and cleaning needle;Clean drive mechanism driving needle assemblies to move back and forth, when driving needle assemblies to move to First terminal point, needle assemblies are located at the top of the putting hole of cleaning position, and when driving needle assemblies to move to the second terminal, liquid pumping needle is located at the top for washing pin pond.Above-mentioned reaction cup cleaning device reduces liquid pumping needle and cleans sordid probability and the probability of liquid pumping needle cross pollution.

Description

Reaction cup cleaning device and sample analyser
Technical field
The utility model is related to sample analysis technical field, more specifically to a kind of reaction cup cleaning device and sample This analyzer.
Background technology
The reaction cup used in sample analysis has magnetic bead, and test substance is combined with magnetic bead., it is necessary to clear during analysis Reaction cup is washed, due to having magnetic bead in reaction cup, causes the cleaning of reaction cup complex.
Magnetic bead, is generally adsorbed onto the wall of cup of reaction cup by the cleaning of reaction cup by external magnetic field, then removes in reaction cup Remaining material, to reach the purpose of cleaning.At present, in reaction cup cleaning process, cleaning fluid is filled to reaction cup in cleaning position When liquid pumping needle is cleaned, liquid pumping needle cleans that sordid probability is larger, and the probability of cross pollution is also larger between liquid pumping needle.
In addition, the mixing position cleaned in reaction cup, the mode according to bias vibration mixes magnetic bead, by eccentric bushing Interference, is typically to be not provided with magnet or set less magnet mixing position, causes the effect for adsorbing magnetic bead poor.
In summary, how reaction cup is cleaned, liquid pumping needle cleans sordid probability and liquid pumping needle intersects dirt to reduce The probability of dye, is current those skilled in the art's urgent problem to be solved.
Utility model content
In view of this, the purpose of this utility model is to provide a kind of reaction cup cleaning device, to reduce liquid pumping needle cleaning not Clean probability and the probability of liquid pumping needle cross pollution.Another object of the present utility model is to provide a kind of with above-mentioned reaction The sample analyser of cup cleaning device.
In order to achieve the above object, the utility model provides following technical scheme:
A kind of reaction cup cleaning device, including:Mounting bracket, reaction cup disk, wiper mechanism, elevating mechanism, and it is installed on institute State the driving part of mounting bracket;
Wherein, the reaction cup disk, which is provided with, is used for the putting hole of placing response cup, and the driving part drives the reaction Cup disk is rotated, and the elevating mechanism drives the wiper mechanism lifting;
The wiper mechanism includes:Needle assemblies, wash pin pond and cleaning drive mechanism;The needle assemblies include:For extracting The liquid pumping needle of liquid in the reaction cup of cleaning position, for filling the clear of cleaning fluid in the reaction cup to the cleaning position Wash pin;The cleaning drive mechanism drives the needle assemblies to move back and forth, when the cleaning drive mechanism drives the needle assemblies When moving to First terminal point, the needle assemblies are located at the top of the putting hole of cleaning position, when the cleaning drive mechanism is driven When the dynamic needle assemblies move to the second terminal, the liquid pumping needle is located at the top for washing pin pond;The pin pond of washing is used for clearly Wash the liquid pumping needle.
Preferably, the bottom of the liquid pumping needle is less than the bottom of the cleaning needle, and when liquid pumping needle extraction is described anti- When answering the liquid in cup, the cleaning needle is higher than the liquid level of the reaction cup;When it is described wash pin pond clean the liquid pumping needle when, institute Cleaning needle is stated higher than the liquid level for washing pin pond.
Preferably, the cleaning drive mechanism includes:Driving part is cleaned, the cleaning driving part and the pin is connected The motion of component.
Preferably, the motion is converted to the linear motion of the cleaning driving part in the straight line of the needle assemblies Motion, and the linear movement direction for cleaning driving part is perpendicular to the linear movement direction of the needle assemblies.
Preferably, the motion is linkage, and the output shaft of the cleaning driving part is fixed with sliding block;
The linkage includes:The pin fixture being fixedly linked with needle assemblies, two ends respectively with the sliding block and described The connecting rod that pin fixture is hinged and connected, the supporting plate provided with first straight line guide rail;
Wherein, the supporting plate is fixedly linked with the cleaning driving part, the pin fixture and the first straight line First slide plate of guide rail is fixedly linked.
Preferably, the needle assemblies and the linkage equal at least two, and the linkage and the pin group Part is corresponded.
Preferably, the motion is converted to the rotary motion of the cleaning driving part in the straight line of the needle assemblies Motion, the linear movement direction of the rotation axis of the rotary motion perpendicular to the needle assemblies.
Preferably, the motion is first gear rackwork, and the first gear rackwork includes:With it is described The first gear that the output shaft of cleaning driving part is fixedly linked, the first rack engaged with the first gear;
Wherein, the pin fixture is fixedly linked with first rack;The needle assemblies and first rack are extremely It is two less, and first rack is corresponded with the needle assemblies.
Preferably, the motion is rotating wheel mechanism, and the rotating wheel mechanism includes:Rotating wheel, connects with first The connection component of fitting and the second connector;
Wherein, the two ends of first connector are fixedly linked with the rotating wheel and second connector respectively, institute The diametrically inclination of the first connector and the rotating wheel is stated, and radial direction of second connector along the rotating wheel is prolonged Stretch;
The output shaft of the rotating wheel and the cleaning driving part is fixedly linked, and the pin fixture is fixed on described the Two connectors;
The needle assemblies and the connection component equal at least two, and a pair of the connection component and the needle assemblies 1 Should.
Preferably, described to wash the bottom that pin pond is located at the reaction cup disk, the reaction cup disk, which is provided with, to be used to take out for described in The pin hole of washing in pin pond is washed described in the insertion of liquid pin, it is described to wash pin hole positioned at the putting hole close to the one of the reaction cup disk center Side.
Preferably, above-mentioned reaction cup cleaning device also includes:For what the liquid in the reaction cup and magnetic bead were mixed Mixing mechanism;
The mixing mechanism includes:The reaction cup, and the eccentric bushing that can be separated with the reaction cup can be coated at; Drive the mixing driving part of the eccentric bushing rotation;
Wherein, the eccentric bushing is provided with the eccentric orfice for being used for accommodating the reaction cup.
Preferably, above-mentioned reaction cup cleaning device is also included located at the telescopic magnet mechanism for mixing position, described telescopic Magnet mechanism includes:
The magnet fixed seat of the mounting bracket is slidingly disposed at,
The first magnet being fixedly linked with the magnet fixed seat,
Drive the magnet fixed seat to move back and forth so that first magnet can be with the mixing position the reaction Cup laminating and the magnet driving part of separation.
Preferably, the magnet driving part drives the magnet by belt gear and second gear rackwork Fixed seat is moved back and forth, and the output shaft of the driving wheel of the belt gear and the magnet driving part is fixedly linked, institute The second gear for stating the driven pulley and the second gear rackwork of belt gear is fixedly linked, the second gear tooth Second rack of bar mechanism is located at the magnet fixed seat.
Preferably, the mixing position and the driven pulley equal at least two, and driven pulley described in any two is synchronous Wheel;The driven pulley, the second gear rackwork, the magnet fixed seat, first magnet and mixing position one One correspondence.
Preferably, the elevating mechanism includes:The lifting fixed seat of the mounting bracket is fixed on, with the lifting fixed seat The lifting driver part being fixedly linked, the elevating lever being connected with the output shaft of the lifting driver part;
Wherein, the elevating lever runs through the lifting fixed seat, and the elevating lever is fixedly linked with the wiper mechanism; The elevating lever provided with two along its axially extending rail plate, and axle of two rail plates on the elevating lever Line is symmetrical.
Preferably, in addition to magnet assemblies, the magnet assemblies include:Magnet cylinder, with the magnet cylinder stationary phase The second magnet even;
Wherein, second magnet is used to adsorbing magnetic bead in the reaction cup, second magnet at least two, and It is sequentially distributed along the circumference of the magnet cylinder;The reaction cup disk and second magnet are respectively positioned in the magnet cylinder.
Preferably, the top of the magnet cylinder has the ring baffle for being used for blocking the reaction cup, and the annular Baffle plate is provided with the resigning mouthful passed through for the needle assemblies, and the top of the magnet cylinder, which is provided with, to be used to pick and place taking for the reaction cup Decontrol mouth.
The application method of reaction cup cleaning device that the utility model is provided is:Reaction cup to be cleaned is placed on reaction On cup disk, reaction cup disk is rotated;When question response cup disk goes to cleaning position, reaction cup disk stops operating, elevating mechanism driving cleaning Mechanism declines so that the liquid in the liquid pumping needle abstraction reaction cup of wiper mechanism, it is to be extracted it is complete after, cleaning needle into reaction cup plus Cleaning fluid is noted, elevating mechanism driving wiper mechanism rises, cleaning drive mechanism driving needle assemblies movement is washed so that liquid pumping needle is moved to The top in pin pond, elevating mechanism driving wiper mechanism decline so that liquid pumping needle clean in pin pond is washed, it is to be cleaned it is complete after, lift Mechanism driving wiper mechanism rises, and (i.e. liquid pumping needle is moved on the putting hole of cleaning position the reset of cleaning drive mechanism driving needle assemblies Side), drawing liquid again is waited, reaction cup disk is rotated again.After question response cup cleaning terminates, take reaction cup away, that is, complete cleaning.
The reaction cup cleaning device that the utility model is provided, pin pond is washed by setting, and driving needle assemblies are moved back and forth Cleaning drive mechanism, by cleaning the cooperation of drive mechanism and elevating mechanism, realize using pin pond is washed to clean liquid pumping needle, Then separate cleaning needle and filled cleaning fluid and cleaning liquid pumping needle to reaction cup, realize individually cleaning liquid pumping needle, more existing skill Art cleaning liquid pumping needle when filling cleaning fluid into reaction cup is compared, effectively reduce liquid pumping needle clean sordid probability and The probability of liquid pumping needle cross pollution.
Reaction cup cleaning device based on above-mentioned offer, the utility model additionally provides a kind of sample analyser, the sample Analyzer includes reaction cup cleaning device, and the reaction cup cleaning device is the reaction cup cleaning dress described in above-mentioned any one Put.
Brief description of the drawings
, below will be to embodiment or prior art in order to illustrate more clearly of the technical scheme in the utility model embodiment The accompanying drawing used required in description is briefly described, it should be apparent that, drawings in the following description are only that this practicality is new The embodiment of type, for those of ordinary skill in the art, on the premise of not paying creative work, can also be according to carrying The accompanying drawing of confession obtains other accompanying drawings.
The structural representation for the reaction cup cleaning device that Fig. 1 provides for the utility model embodiment;
The structural representation of wiper mechanism in the reaction cup cleaning device that Fig. 2 provides for the utility model embodiment;
A kind of structural representation of motion in the reaction cup cleaning device that Fig. 3 provides for the utility model embodiment;
Another structural representation of motion in the reaction cup cleaning device that Fig. 4 provides for the utility model embodiment Figure;
The structural representation of elevating mechanism in the reaction cup cleaning device that Fig. 5 provides for the utility model embodiment;
The structural representation of magnet assemblies in the reaction cup cleaning device that Fig. 6 provides for the utility model embodiment;
The structural representation of telescopic magnet mechanism in the reaction cup cleaning device that Fig. 7 provides for the utility model embodiment Figure;
The structural representation of mixing mechanism in the reaction cup cleaning device that Fig. 8 provides for the utility model embodiment.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment obtained, belongs to the scope of the utility model protection.
As shown in figures 1-8, the reaction cup cleaning device that the utility model embodiment is provided, including:Mounting bracket, reaction cup disk 6, wiper mechanism 4, elevating mechanism 5, and it is installed on the driving part of mounting bracket.
Above-mentioned reaction cup disk 6, which is provided with, is used for the putting hole 601 of placing response cup 9,6 turns of driving part driving reaction cup disk It is dynamic.The above-mentioned driving of elevating mechanism 5 wiper mechanism 4 is lifted.
Above-mentioned wiper mechanism 4 includes:Needle assemblies, wash pin pond 409 and cleaning drive mechanism;Needle assemblies include:For extracting The liquid pumping needle 405 of liquid in the reaction cup 9 of cleaning position, the cleaning needle for filling cleaning fluid in the reaction cup 9 to cleaning position 404;Clean drive mechanism driving needle assemblies to move back and forth, then there are two terminals in needle assemblies reciprocatory movement, respectively the One terminal and the second terminal.When cleaning drive mechanism driving needle assemblies move to First terminal point, needle assemblies are located at cleaning position The top of putting hole 601, when cleaning drive mechanism driving needle assemblies move to the second terminal, liquid pumping needle 405, which is located at, washes pin pond 409 top;Washing pin pond 409 is used to clean liquid pumping needle 405.
It is understood that the top of putting hole 601 refers to the surface of putting hole 601, i.e., when needle assemblies are located at cleaning During the top of the putting hole 601 of position, needle assemblies are relative with the putting hole 601;Correspondingly, the top for washing pin pond 409 refers to wash pin When the surface in pond 409, i.e. liquid pumping needle 405 are located at the top for washing pin pond 409, liquid pumping needle 405 is relative with washing pin pond 409.
Liquid, the cleaning needle 404 that liquid in reaction cup 9 is remained before being cleaned for reaction cup 9 are filled into reaction cup The mixing for the cleaning fluid that the liquid that cleaning fluid or reaction cup 9 are remained before cleaning is filled with cleaning needle 404 into reaction cup Liquid.
The application method of reaction cup cleaning device that the utility model embodiment is provided is:Reaction cup 9 to be cleaned is put Put on reaction cup disk 6, reaction cup disk 6 is rotated;When question response cup disk 6 goes to cleaning position, reaction cup disk 6 stops operating, lifting The driving wiper mechanism 4 of mechanism 5 declines so that the liquid in the abstraction reaction of liquid pumping needle 405 cup 9 of wiper mechanism 4, to be extracted complete Afterwards, cleaning needle 404 fills cleaning fluid into reaction cup 9, and the driving wiper mechanism 4 of elevating mechanism 5 rises, cleaning drive mechanism driving Needle assemblies are moved, so that liquid pumping needle 405 moves to the top for washing pin pond 409, the driving wiper mechanism 4 of elevating mechanism 5 declines so that take out Liquid pin 405 is cleaned in pin pond 409 is washed, it is to be cleaned it is complete after, elevating mechanism 5 driving wiper mechanism 4 rise, cleaning drive mechanism drive Dynamic needle assemblies reset (top of putting hole 601 that i.e. liquid pumping needle 405 moves to cleaning position), wait drawing liquid again, reaction cup disk 6 is again Rotate.Being put into and taking away for above-mentioned reaction cup 9 can be completed by pipetting mechanism.
It is understood that when having magnetic bead in reaction cup 9, above-mentioned reaction cup cleaning device also includes being used to adsorb magnetic The magnet and mixing mechanism 8 of pearl.Reaction cup 9, which is reached, passes through magnet adsorption before cleaning position;When reaction cup 9 is run behind cleaning position To when mixing position, reaction cup disk 6 is stopped operating, and mixing mechanism 8 brings into operation, after mixing, and reaction cup disk 6 is rotated again, and Carry out absorption magnetic bead, drawing liquid, filling cleaning fluid and and cleaning liquid pumping needle 405 again according to above-mentioned steps.Question response cup 9 is cleaned After end (cleaning reaction cup more than 9 three times), take reaction cup 9 away, that is, complete cleaning.
The reaction cup cleaning device that the utility model embodiment is provided, pin pond 409 is washed by setting, and driving needle assemblies Reciprocating cleaning drive mechanism, by cleaning the cooperation of drive mechanism and elevating mechanism 5, realizes to utilize and washes pin pond 409 To clean liquid pumping needle 405, then cleaning needle 404 is separated and has filled cleaning fluid and cleaning liquid pumping needle 405 to reaction cup 9, realized Individually cleaning liquid pumping needle 405, compared with prior art, when filling cleaning fluid into reaction cup 9, cleaning liquid pumping needle 405 is compared, and is effectively subtracted The probability that liquid pumping needle 405 cleans sordid probability and the cross pollution of liquid pumping needle 405 is lacked.
Preferably, above-mentioned driving part is stepper motor.Certainly, it is other actuators driving part also to may be selected, for example Other kinds of motor, it is not limited to this.
In order to avoid cleaning needle 404 is contaminated, the bottom of above-mentioned liquid pumping needle 405 is less than the bottom of cleaning needle 404, and ought take out During liquid in liquid pin 405 abstraction reaction cup 9, cleaning needle 404 is higher than the liquid level of reaction cup 9;Liquid pumping needle is cleaned when washing pin pond 409 When 405, cleaning needle 404 is higher than the liquid level for washing pin pond 409.
In above-mentioned reaction cup cleaning device, cleaning drive mechanism driving needle assemblies are moved back and forth, and the reciprocating motion can be straight Line is moved, also can curvilinear motion.For the ease of realizing, simplify structure, the prioritizing selection reciprocating motion is linear motion.Further Ground, radial direction of the cleaning drive mechanism driving needle assemblies along reaction cup disk 6 moves along a straight line.Certainly, cleaning driving machine also may be selected Structure drives string of the needle assemblies along reaction cup disk 6 to move along a straight line, it is not limited to above-described embodiment.
Moved back and forth for the ease of driving needle assemblies, above-mentioned cleaning drive mechanism includes:Clean driving part 401, connection Clean the motion of driving part 401 and needle assemblies.So, cleaning driving part 401 drives needle assemblies by motion Move back and forth, be easy to implement, facilitate setting;Also allow for reducing part.Certainly, cleaning driving part 401 also may be selected direct Be connected with needle assemblies, when simply needle assemblies are more, clean driving part 401 number is more, structure is more complicated.
Generally cleaning driving part 401 has two kinds of driving shapes, and one kind moves along a straight line, for example, clean driving part 401 and be Linear stepping motor or cylinder;Another is rotary motion, and it is rotating stepper motor or rotation for example to clean driving part 401 Rotaring cylinder.The drive form for cleaning driving part 401 is different, and motion will be different.
When cleaning driving part 401 is driven using linear motion, above-mentioned motion will clean driving part 401 Linear motion be converted to the linear motions of needle assemblies, and cleaning driving part 401 linear movement direction perpendicular to needle assemblies Linear movement direction.Specifically, the linear movement direction of cleaning driving part 401 is identical with the axial direction of reaction cup disk 6, pin group The linear movement direction of part is identical with the radial direction of reaction cup disk 6.
Preferably, motion is linkage, and the output shaft of cleaning driving part 401 is fixed with sliding block 408;Above-mentioned company Linkage includes:The pin fixture 403 being fixedly linked with needle assemblies, two ends are hinged phase with sliding block 408 and pin fixture 403 respectively Connecting rod 402 even, the supporting plate 406 provided with first straight line guide rail 407;Wherein, supporting plate 406 is consolidated with cleaning driving part 401 Fixed to be connected, the first slide plate of pin fixture 403 and first straight line guide rail 407 is fixedly linked, as shown in Figure 2.
It is understood that first straight line guide rail 407 includes:First slide rail, and first be slidably matched with the first slide rail Guide pad;First guide pad is fixed on supporting plate 406.
Usual reaction cup disk 6 is located at least two putting holes 601, to ensure to place at least two reaction cups 9, so as to accelerate Cleaning efficiency.When putting hole 601 at least two, needle assemblies, pin pond 409 equal at least two is washed, and needle assemblies, wash pin pond 409 correspond with putting hole 601.
When above-mentioned needle assemblies at least two, prioritizing selection linkage at least two, and linkage and pin group Part is corresponded.Now, the connecting rod 402 of linkage is hinged with same sliding block 408, specifically, and connecting rod 402 is along sliding block 408 Circumference be uniformly distributed.So, the synchronizing moving of any two needle assemblies, i.e., all needle assemblies linkages are realized, it is ensured that Precision is driven, so as to ensure that normal wash, structure is also simplify.
Certainly, it is other structures aforementioned link mechanism also to may be selected, as long as ensureing its function, it is not limited to above-mentioned Embodiment.
When cleaning driving part 401 is driven using rotary motion, above-mentioned motion will clean driving part 401 Rotary motion be converted to the linear motions of needle assemblies, the rotation axis of rotary motion is perpendicular to the linear motion side of needle assemblies To as shown in Figure 3 and Figure 4.
Preferably, above-mentioned motion is first gear rackwork, and the first gear rackwork includes:Driven with cleaning The first gear 411 that the output shaft of dynamic component 401 is fixedly linked, the first rack 410 engaged with first gear 411;Wherein, pin Fixture 403 is fixedly linked with the first rack 410.
When needle assemblies at least two, above-mentioned first rack 410 at least two, and the first rack 410 and needle assemblies one One correspondence.As shown in figure 3, the first rack 410 is four.
Certainly, it is other structures above-mentioned motion also to may be selected.Specifically, as shown in figure 4, above-mentioned motion is rotation Rotating wheel mechanisms that, the rotating wheel mechanism includes:Rotating wheel 412, the connection group with the first connector 413 and the second connector 414 Part;Wherein, the two ends of the first connector 413 are fixedly linked with the connector 414 of rotating wheel 412 and second respectively, the first connector 413 with the diametrically inclination of rotating wheel 412, and the second radially extending along rotating wheel 412 of connector 414;Rotating wheel 412 with The output shaft of cleaning driving part 401 is fixedly linked, and pin fixture 403 is fixed on the second connector 414.
It is understood that there is angle between the first connector 413 and the second connector 414, and the angle is obtuse angle. For the ease of realizing, the first connector 413 and the circumferential side wall of rotating wheel 412 are fixedly linked.
When needle assemblies at least two, above-mentioned connection component at least two, and a pair of connection component and needle assemblies 1 Should.Preferably, circumference of the connection component along rotating wheel 412 is uniformly distributed.
In order to improve compactedness, reduce the volume of whole device, it is above-mentioned to wash the bottom that pin pond 409 is located at reaction cup disk 6, instead Answer cup disk 6 be provided be used to inserting for liquid pumping needle 405 wash pin pond 409 wash pin hole 602.It is above-mentioned for the ease of setting magnet assemblies 3 Pin hole 602 is washed positioned at putting hole 601 close to the side at the center of reaction cup disk 6, as shown in Figure 2.
It should be noted that during putting hole 601 at least two, circumference of the prioritizing selection putting hole 601 along reaction cup disk 6 It is uniformly distributed.Now, putting hole 601 is identical with washing the number of pin hole 602, and putting hole 601 is corresponded with washing pin hole 602, is put Put hole 601 and be located at the periphery for washing pin hole 602.
In above-mentioned reaction cup cleaning device, when having magnetic bead in the reaction cup 9 for needing to clean, it is necessary to set mixing mechanism 8, the liquid in reaction cup 9 and magnetic bead are mixed using mixing mechanism 8.Mixing mechanism 8 is real generally by the way of eccentric vibrating Now mix.Specifically, as shown in figure 8, mixing mechanism 8 includes:Eccentric bushing 805, and the mixing driving that driving eccentric bushing 805 rotates Part 801;Wherein, eccentric bushing 805 is provided with the eccentric orfice 806 for being used for accommodating reaction cup 9.When needing to mix, start to mix and drive Dynamic component 801, eccentric bushing 805 rotates, and the reaction cup 9 in eccentric orfice 806 starts vibration, with the vibration of reaction cup 9, instead The liquid in cup 9 and magnetic bead mixing are answered, so as to realize well mixed.
Preferably, eccentric bushing 805 can be coated at reaction cup 9 and can be separated with reaction cup 9, when eccentric bushing 805 and instead Answer after the separation of cup 9, reaction cup 9 is separated with eccentric orfice 806.Realize that eccentric bushing 805 is separated with reaction cup 9, there are various ways, example Driving part is such as set to realize moving down for eccentric bushing 805.
Preferably, it is motor to mix driving part 801, certainly, other complex driving structures also may be selected, not It is confined to this.
Above-mentioned mixing mechanism 8 also includes the mixing mounting seat 802 for being fixed on mounting bracket, mixes driving part 801 and is fixed on Mounting seat 802 is mixed, installation is facilitated.
Preferably, above-mentioned mixing mechanism 8 also includes being fixed on the liquid-proof cover 803 for mixing mounting seat 802, the liquid-proof cover 803 Cover in the top for mixing driving part 801.So, liquid-proof cover 803 is utilized, it is to avoid the liquid such as water, which enters, mixes driving part 801, liquid-proof is realized, so as to improve security reliability.
In above-mentioned reaction cup cleaning device, the mixing time of mixing mechanism 8 is shorter, and the residence time of reaction cup disk 6 compared with It is long.When having magnetic bead in the reaction cup 9 for needing to clean, it is necessary to set the magnetic bead in magnet adsorption reaction cup 9.In order to fully sharp With free time, absorption magnetic bead effect is improved, above-mentioned reaction cup cleaning device is also included located at the telescopic Ferromagnet machine for mixing position Structure 7, the telescopic magnet mechanism 7 includes:Magnet fixed seat 704, the first magnet 705 and magnet driving part 701;Wherein, magnetic Ferropexy seat 704 is slidingly disposed at mounting bracket, and the first magnet 705 is fixedly linked with magnet fixed seat 704, magnet driving part 701 drive magnet fixed seats 704 reciprocatingly slide so that the first magnet 705 can be fitted and separated with mixing the reaction cup 9 of position.
Above-mentioned reaction cup cleaning device, it is mobile eccentric after mixing mechanism 8 mixes the liquid in reaction cup 9 and magnetic bead Set 805, after eccentric bushing 805 is separated with reaction cup 9, the drive magnet fixed seat 704 of magnet driving part 701 is slided so that the One magnet 705 is moved to reaction cup 9, until the first magnet 705 is fitted with reaction cup 9, adsorbs magnetic bead;Rotated in reaction cup disk 6 Before, the reverse slide of 701 drive magnet fixed seat of magnet driving part 704 so that the first magnet 705 realizes away from reaction cup 9 One magnet 705 and the separation of reaction cup 9.
Above-mentioned reaction cup cleaning device, realizes and is mixing position using the first magnet 705 absorption magnetic bead, when adding absorption Between, adsorption effect is effectively increased, the loss of magnetic bead is reduced.
First magnet 705 is installed for convenience, the first magnet 705 of selection is consolidated by the first magnet fixed plate 706 and magnet Reservation 704 is fixedly linked.
Preferably, above-mentioned magnet driving part 701 is stepper motor.Certainly, above-mentioned magnet driving part 701 also may be selected For other kinds of motor, it is not limited to this.
The above-mentioned drive magnet fixed seat 704 of magnet driving part 701 reciprocatingly slides so that the first magnet 705 can be with mixing The reaction cup 9 of position is fitted and separated, and there are various structures.Preferably, as shown in fig. 7, magnet driving part 701 is passed by belt Motivation structure and second gear rackwork drive magnet fixed seat 704 reciprocatingly slide, wherein, the driving wheel of belt gear with The output shaft of magnet driving part 701 is fixedly linked, and the of the driven pulley 708 of belt gear and second gear rackwork Two gears 707 are fixedly linked, and the second rack of pinion and rack is located at magnet fixed seat 704.
In above-mentioned telescopic magnet mechanism 7, along the length direction of the second rack, driven pulley 708 is fixedly installed.So, magnetic When iron driving part 701 drives, driving wheel drives driven pulley 708 to rotate, and second gear 707 is rotated with driven pulley 708, the second tooth Bar is moved along its length.
Position at least two is generally mixed, correspondingly, driven pulley 708 at least two, and any two driven pulley 708 is Synchronizing wheel;Driven pulley 708, second gear rackwork, magnet fixed seat 704 and mixing position are corresponded.On may be appreciated, Driving wheel and all driven pulleys 708 share a root skin band 709.
Above-mentioned telescopic magnet mechanism 7 realizes the linkage of the first magnet 705, i.e., the first magnet 705 is by same magnetic Iron driving part 701 is driven, and reduces part, simplifies structure, also improves synchronization dependability.
In order to reduce part, above-mentioned second rack is integral type structure with magnet fixed seat 704, i.e., in magnet fixed seat The second rack is processed on 704.
Above-mentioned magnet fixed seat 704 is slidingly disposed at mounting bracket, specifically, and magnet fixed seat 704 passes through second straight line Guide rail 703 is slidingly disposed at mounting bracket.Second straight line guide rail 703 includes:Second slide rail, and be slidably matched with the second slide rail Second guide pad;Second guide pad is fixedly linked with magnet fixed seat 704, and the second slide rail is fixedly linked with mounting bracket.
As shown in figure 5, above-mentioned elevating mechanism 5 includes:The lifting fixed seat 503 of mounting bracket is fixed on, with lifting fixed seat 503 lifting driver parts 505 being fixedly linked, the elevating lever 501 being connected with the output shaft of lifting driver part 505;Wherein, rise Bar 501 is dropped to be fixedly linked with wiper mechanism 4 through lifting fixed seat 503, and elevating lever 501.Above-mentioned lifting driver part 505 can For motor or cylinder.For the ease of using, above-mentioned lifting driver part 505 is spindle motor.
Further, above-mentioned elevating lever 501 is provided with two along its axially extending rail plate 502, and two slips are led Rail 502 is distributed on the axisymmetrical of elevating lever 501.It is understood that elevating lever 501 passes through rail plate 502 and lifting Fixed seat 503 is slidably matched.So, using double guide rail structures, it is to avoid the unbalance stress that single guide rail is brought, it ensure that simultaneously Running precision is lifted, reliability is improved.
For the ease of installing, above-mentioned lifting driver part 505 is fixed by lifting support frame 504 with lifting fixed seat 503 It is connected.
When having magnetic bead in the reaction cup 9 for needing to clean, it is necessary to set the magnetic bead in magnet adsorption reaction cup 9.Specifically Ground, above-mentioned reaction cup cleaning device also includes magnet assemblies, as shown in fig. 6, above-mentioned magnet assemblies 3 include:Magnet cylinder 301, The second magnet 303 being fixedly linked with magnet cylinder 301;Wherein, the magnetic bead that the second magnet 303 is used in adsorption reaction cup 9, the Two magnet 303 at least two, and be sequentially distributed along the circumference of magnet cylinder 301;The equal position of 6 and second magnet of reaction cup disk 303 In in magnet cylinder 301.
After above-mentioned magnet assemblies 3, because magnet cylinder 301 is circumferential closed type structure, and the second magnet 303 is along magnet The circumference of cylinder 301 is sequentially distributed, then can increase adsorption time, improves adsorption effect, reduces the loss of magnetic bead;Meanwhile, magnetic Work durm body 301 serves certain protective effect, it is to avoid second magnet 303 is by ectocine;Also improve aesthetics.
Certainly, it is other structures magnet assemblies 3 also to may be selected, it is not limited to above-described embodiment.
For the ease of fixing the second magnet 303, above-mentioned magnet assemblies 3 also include the second magnet fixed plate 302, the second magnet 303 are fixedly linked by the second magnet fixed plate 302 and magnet cylinder 301.Specifically, the second magnet fixed plate 302 is fixed on Magnet cylinder 301, the second magnet 303 is fixed on the second magnet fixed plate 302.
Preferably, a second magnet fixed seat 302 is fixed with least two piece second magnet 303;Second magnet fixed seat 302 at least two, and be uniformly distributed along the circumference of magnet cylinder 301.In order to improve adsorption effect, along magnet cylinder 301 It is circumferential, there are two the second magnet fixed seats 302 between two adjacent mixing mechanisms 8.
Further, the top of above-mentioned magnet cylinder 301 has the ring baffle for being used for blocking reaction cup 9, and annular gear The resigning mouthful 305 that plate passes through provided with needle-supply assembly, the top of magnet cylinder 301 be provided be used to picking and placeing reaction cup 9 pick and place opening 304.It is understood that reaction cup 9 is located at the lower section of ring baffle.
Above-mentioned magnet assemblies 3, blocking to reaction cup 9 is realized by ring baffle, it is to avoid outer environmental liquids enter Reaction cup 9 and influence cleaning performance.
In above-mentioned reaction cup cleaning device, during with above-mentioned telescopic magnet mechanism 7, magnet cylinder 301 is opened with resigning Mouthful, the first magnet 705 is contacted with reaction cup 9 during ensureing that the first magnet 705 reaches mixing position.
In above-mentioned reaction cup cleaning device, mounting bracket provides overall installation and fixed support.Install and prop up for convenience Support, above-mentioned mounting bracket includes:Bearing 1, and it is fixed on the installing plate 2 on the top of bearing 1;Wherein, driving part, magnet assemblies 3, liter Descending mechanism 5 and mixing mechanism 8 are both secured to installing plate 2.
Preferably, driving part, magnet assemblies 3 are both secured to the top surface of installing plate 2, and elevating mechanism 5 is fixed on installing plate 2 Bottom surface, mixing mechanism 8 is fixed on the side of installing plate 2.
Specifically, magnet cylinder 301 is fixed on installing plate 2, and installing plate 2 is fixed in the pin pond 409 of washing of wiper mechanism 4, rises Drop fixed seat 503 is fixed on installing plate 2, and magnet driving part 701 is fixed on magnet fixed seat 704 by magnet fixed mount 702, Mix mounting seat 802 and be fixed on installing plate 2.
It is understood that being fixed on installing plate 2 when mixing mounting seat 802, mix driving part 801 and be located at installing plate 2 Lower section when, installing plate 2 has the resigning opening passed through for eccentric bushing 805.
The reaction cup cleaning device provided based on above-described embodiment, the utility model embodiment additionally provides a kind of sample point Analyzer, the sample analyser includes reaction cup cleaning device, and the reaction cup cleaning device is the reaction cup described in above-described embodiment Cleaning device.
Because the reaction cup cleaning device that above-described embodiment is provided has above-mentioned technique effect, the utility model embodiment is carried The sample analyser of confession has the reaction cup cleaning device that above-described embodiment is provided, then the sample that the utility model embodiment is provided Analyzer also has correspondingly technique effect, repeats no more herein.
The foregoing description of the disclosed embodiments, enables those skilled in the art to realize or use the utility model. A variety of modifications to these embodiments will be apparent for a person skilled in the art, general original as defined herein Reason can in other embodiments be realized in the case where not departing from spirit or scope of the present utility model.Therefore, this practicality is new Type is not intended to be limited to the embodiments shown herein, and is to fit to and principles disclosed herein and features of novelty phase Consistent most wide scope.

Claims (18)

1. a kind of reaction cup cleaning device, it is characterised in that including:Mounting bracket, reaction cup disk, wiper mechanism, elevating mechanism, and It is installed on the driving part of the mounting bracket;
Wherein, the reaction cup disk, which is provided with, is used for the putting hole of placing response cup, and the driving part drives the reaction cup disk Rotate, the elevating mechanism drives the wiper mechanism lifting;
The wiper mechanism includes:Needle assemblies, wash pin pond and cleaning drive mechanism;The needle assemblies include:For extracting cleaning The liquid pumping needle of liquid in the reaction cup of position, the cleaning for filling cleaning fluid in the reaction cup to the cleaning position Pin;The cleaning drive mechanism drives the needle assemblies to move back and forth, when the cleaning drive mechanism drives the needle assemblies fortune When moving to First terminal point, the needle assemblies are located at the top of the putting hole of cleaning position, when the cleaning drive mechanism driving When the needle assemblies move to the second terminal, the liquid pumping needle is located at the top for washing pin pond;The pin pond of washing is used to clean The liquid pumping needle.
2. reaction cup cleaning device according to claim 1, it is characterised in that the bottom of the liquid pumping needle is clear less than described The bottom of pin is washed, and when the liquid pumping needle extracts the liquid in the reaction cup, the cleaning needle is higher than the reaction cup Liquid level;When it is described wash pin pond and clean the liquid pumping needle when, the cleaning needle is higher than the liquid level for washing pin pond.
3. reaction cup cleaning device according to claim 1, it is characterised in that the cleaning drive mechanism includes:Cleaning Driving part, connects the motion of the cleaning driving part and the needle assemblies.
4. reaction cup cleaning device according to claim 3, it is characterised in that the motion drives the cleaning The linear motion of part is converted to the linear motion of the needle assemblies, and the linear movement direction of the cleaning driving part is vertical In the linear movement direction of the needle assemblies.
5. reaction cup cleaning device according to claim 4, it is characterised in that
The motion is linkage, and the output shaft of the cleaning driving part is fixed with sliding block;
The linkage includes:The pin fixture being fixedly linked with needle assemblies, two ends are solid with the sliding block and the pin respectively Determine the connecting rod that part is hinged and connected, the supporting plate provided with first straight line guide rail;
Wherein, the supporting plate is fixedly linked with the cleaning driving part, the pin fixture and the first straight line guide rail The first slide plate be fixedly linked.
6. reaction cup cleaning device according to claim 5, it is characterised in that the needle assemblies and the linkage are equal At least two, and the linkage and needle assemblies one-to-one corresponding.
7. reaction cup cleaning device according to claim 5, it is characterised in that the motion drives the cleaning The rotary motion of part is converted to the linear motion of the needle assemblies, and the rotation axis of the rotary motion is perpendicular to the pin group The linear movement direction of part.
8. reaction cup cleaning device according to claim 7, it is characterised in that the motion is first gear rack Mechanism, the first gear rackwork includes:The first gear being fixedly linked with the output shaft of the cleaning driving part, with First rack of the first gear engagement;
Wherein, the pin fixture is fixedly linked with first rack;The needle assemblies are at least with first rack Two, and first rack and needle assemblies one-to-one corresponding.
9. reaction cup cleaning device according to claim 7, it is characterised in that the motion is rotating wheel mechanism, The rotating wheel mechanism includes:Rotating wheel, the connection component with the first connector and the second connector;
Wherein, the two ends of first connector are fixedly linked with the rotating wheel and second connector respectively, and described A connection piece and the diametrically inclination of the rotating wheel, and the second connector radially extending along the rotating wheel;
The rotating wheel and the output shaft of the cleaning driving part are fixedly linked, and the pin fixture is fixed on described second and connected Fitting;
The needle assemblies and the connection component equal at least two, and the connection component and needle assemblies one-to-one corresponding.
10. reaction cup cleaning device according to claim 1, it is characterised in that the pin pond of washing is positioned at the reaction cup The bottom of disk, the reaction cup disk, which is provided with, is used for the pin hole of washing for washing pin pond described in liquid pumping needle insertion, described to wash pin hole position In the putting hole close to the side of the reaction cup disk center.
11. reaction cup cleaning device according to claim 1, it is characterised in that also include:For by the reaction cup Liquid and magnetic bead mix mixing mechanism;
The mixing mechanism includes:The reaction cup, and the eccentric bushing that can be separated with the reaction cup can be coated at;Driving The mixing driving part of the eccentric bushing rotation;
Wherein, the eccentric bushing is provided with the eccentric orfice for being used for accommodating the reaction cup.
12. reaction cup cleaning device according to claim 11, it is characterised in that also including located at the telescopic of mixing position Magnet mechanism, the telescopic magnet mechanism includes:
The magnet fixed seat of the mounting bracket is slidingly disposed at,
The first magnet being fixedly linked with the magnet fixed seat,
The magnet fixed seat is driven to move back and forth so that first magnet can be pasted with the reaction cup of the mixing position The magnet driving part for closing and separating.
13. reaction cup cleaning device according to claim 12, it is characterised in that the magnet driving part passes through belt Transmission mechanism and second gear rackwork drive the magnet fixed seat to move back and forth, the driving wheel of the belt gear It is fixedly linked with the output shaft of the magnet driving part, the driven pulley of the belt gear and the second gear rack The second gear of mechanism is fixedly linked, and the second rack of the second gear rackwork is located at the magnet fixed seat.
14. reaction cup cleaning device according to claim 13, it is characterised in that the mixing position is equal with the driven pulley At least two, and driven pulley described in any two is synchronizing wheel;It is the driven pulley, the second gear rackwork, described Magnet fixed seat and mixing position are corresponded.
15. reaction cup cleaning device according to claim 1, it is characterised in that the elevating mechanism includes:It is fixed on institute The lifting fixed seat of mounting bracket is stated, the lifting driver part being fixedly linked with the lifting fixed seat, with the lifting drive division The connected elevating lever of the output shaft of part;
Wherein, the elevating lever runs through the lifting fixed seat, and the elevating lever is fixedly linked with the wiper mechanism;It is described Elevating lever provided with two along its axially extending rail plate, and axis pair of two rail plates on the elevating lever Claim distribution.
16. the reaction cup cleaning device according to any one in claim 1-15, it is characterised in that also including group of magnets Part, the magnet assemblies include:Magnet cylinder, the second magnet being fixedly linked with the magnet cylinder;
Wherein, second magnet is used to adsorbing magnetic bead in the reaction cup, second magnet at least two, and along institute The circumference for stating magnet cylinder is sequentially distributed;The reaction cup disk and second magnet are respectively positioned in the magnet cylinder.
17. reaction cup cleaning device according to claim 16, it is characterised in that the top of the magnet cylinder, which has, to be used In the ring baffle for blocking the reaction cup, and the ring baffle is provided with the resigning mouthful passed through for the needle assemblies, the magnetic The top of work durm body be provided be used to picking and placeing the reaction cup pick and place opening.
18. a kind of sample analyser, including reaction cup cleaning device, it is characterised in that the reaction cup cleaning device is as weighed Profit requires the reaction cup cleaning device described in any one in 1-17.
CN201621030476.0U 2016-08-31 2016-08-31 Reaction cup cleaning device and sample analyser Active CN206435557U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106269753A (en) * 2016-08-31 2017-01-04 四川迈克生物医疗电子有限公司 Reaction cup cleans device and sample analyser
CN110082549A (en) * 2018-01-25 2019-08-02 深圳市新产业生物医学工程股份有限公司 Cleaning device and chemiluminescence detector
CN110160854A (en) * 2019-05-23 2019-08-23 深圳安赛诊断技术有限公司 It is a kind of to keep the device of bead suspension uniformity, method and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106269753A (en) * 2016-08-31 2017-01-04 四川迈克生物医疗电子有限公司 Reaction cup cleans device and sample analyser
CN106269753B (en) * 2016-08-31 2019-06-28 迈克医疗电子有限公司 Reaction cup cleaning device and sample analyser
CN110082549A (en) * 2018-01-25 2019-08-02 深圳市新产业生物医学工程股份有限公司 Cleaning device and chemiluminescence detector
CN110082549B (en) * 2018-01-25 2023-10-10 深圳市新产业生物医学工程股份有限公司 Cleaning device and chemiluminescence detector
CN110160854A (en) * 2019-05-23 2019-08-23 深圳安赛诊断技术有限公司 It is a kind of to keep the device of bead suspension uniformity, method and application thereof

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