CN206198085U - A kind of big animal spinal cord moment impact damage model modeling beating device - Google Patents

Abstract

The utility model discloses a kind of big animal spinal cord moment impact damage model modeling beating device, including base, base is provided with some pillars and some adjusting nuts, connecting plate is set on pillar, connecting plate is provided with screw mandrel and some lead columns, screw mandrel and lead column are fixedly connected with level(l)ing device, and screw mandrel slidably connects the counter above level(l)ing device, and screw mandrel is fixedly connected with the handwheel above counter；Screw mandrel also slidably connects the slide plate below level(l)ing device, and slide plate is fixedly connected with fixed connecting rod, and fixed link rotatable is connected with translation connecting rod, and translation link rotatable is connected with plane fine-tuning device, and plane fine-tuning device is provided with aiming percussion device.Normalizing operation makes the repeatable stronger of experiment, it is adaptable to which various large-scale experiment animal spinal cords clash into the making of wound model, is adapted to laboratory requirements at different levels, can be mass, with good scientific research value and social economic value.

Description

A kind of big animal spinal cord moment impact damage model modeling beating device

Technical field

The utility model is related to animal experiment device technical field, it particularly relates to a kind of big animal spinal cord moment hits Hit damage model modeling impactor.

Background technology

The incidence of disease of spinal cord injury is raised year by year and disability rate is very high, its healthy, the work(that have had a strong impact on patient Energy and quality of life, heavy financial burden is brought to society and family.Research to spinal cord injury at present largely launches, but Research to the pathomechanism such as bleeding, swelling, tissue liquefaction and necrosis, calcification, nerve regneration after spinal cord injury need to be broken through, in advance Still it is very poor afterwards, therefore treatment spinal cord injury is also difficult to the wide gap gone beyond into one.

For the method for the spinal cord injury that seeks treatment, it is still necessary to carry out substantial amounts of spinal cord injury experimental study, its research is right As being mainly rodent, such as big mouse, thus existing prepare spinal cord injury model instrument to be also aimed at rodent small Animal, and toy spinal anatomy is relatively small, damage of the experimental implementation process to toy will be bigger.And take big Animal carries out experimental study, and its spinal cord is thick, and operation technique space is bigger, dissects and modus operandi is closer to human myeloid, more Easily clinical conversion, it is therefore desirable to carry out more big animals（The larger animals such as dog, pig, monkey, cat, rabbit）Spinal cord injury research, so And at present both at home and abroad without a standardized big animal spinal cord injury strike instrument.The big animal spinal cord injury research reported In spinal cord injury model method used include that haemostatic clamp clamp method spinal cord compression wound model, weight-drop method spinal cord beating hinder mould Type etc., wherein spinal cord compression wound model have used haemostatic clamp clamp animal spinal cord, and Shortcomings have clamp time and the strength can not The problem being precisely controlled, this can cause the variability of degrees of spinal cord injury big, and extruding wound model and clinical practice situation have compared with Big gap（Because the damage mechanisms of clinical spinal cord injury are generally contusion of spinal cord rather than crush injury）, to ensure the science of research, Spinal cord moment impact damage model should be used；The weight-drop method spinal cord beating wound model reported in big zooscopy at present, It is simply equipped, it is impossible to ensure standardization, precision and the repeatability of spinal cord injury model.

For the problem in correlation technique, effective solution is not yet proposed at present.

Utility model content

For the above-mentioned technical problem in correlation technique, the utility model proposes a kind of big animal spinal cord moment impact damage Model modeling beating device, can make accurate, easy to use strike standard, portability, applied widely, moderate cost.

To realize above-mentioned technical purpose, what the technical solution of the utility model was realized in：

A kind of big animal spinal cord moment impact damage model modeling beating device, including base, the base are provided with some Root pillar and some adjusting nuts, the pillar upper junction plate, the connecting plate are provided with screw mandrel and some lead columns, described Screw mandrel and lead column are fixedly connected with level(l)ing device, and the screw mandrel is slidably connected located at the top of level(l)ing device Counter, the screw mandrel is fixedly connected with the handwheel located at the top of counter；The screw mandrel is also slidably connected located at level The slide plate of the lower section of adjusting means, the slide plate is fixedly connected with fixed connecting rod, and the fixed link rotatable is connected with translation company Bar, the translation link rotatable is connected with plane fine-tuning device, and the plane fine-tuning device is provided with aiming percussion device, described Aim at percussion device and be provided with HeiFin device, the HeiFin device is connected with the plane fine-tuning device；A piece institute State and switch enclosure is fixedly connected with the right side of pillar, the switch enclosure is connected by wire with the aiming percussion device.

Further, the level(l)ing device includes substrate one, and the front side of the substrate one is provided with X to level meter, institute The left side for stating substrate one is provided with Y-direction level meter.

Further, the plane fine-tuning device includes substrate two, X is slidably connected on the substrate two and is filled to fine setting Put, the X is provided with aiming percussion device to Y-direction micromatic setting, the Y-direction micromatic setting is slidably connected on micromatic setting.

Further, the aiming percussion device includes pedestal, and the pedestal is provided with laser fixed seat, the laser Device fixed seat is provided with some adjusting screws, and laser is provided with the laser fixed seat, and seat centering is provided with the pedestal Spheroid, the seat centering spheroid is provided with through hole, and one end of the laser is consolidated by the through hole and seat centering spheroid Fixed connection, the seat centering spheroid is fixedly connected with hollow magnetic means, the hollow magnetic means connection by the through hole There is peening hammer device；The laser is connected by wire with the laser switch in the switch enclosure, the hollow magnetic Power apparatus are connected by wire with the electromagnetic switch in the switch enclosure.

Further, the hollow magnetic means includes magnetic coil, and the magnetic coil is connected with magnetic plate.

Further, the peening hammer device includes peening hammer passage, and the peening hammer passage slidably connects peening hammer, Sight hole is provided with the peening hammer.

Further, the HeiFin device includes the support on the outside of hollow magnetic means, is set on the support There is adjusting screw.

Further, it is additionally provided with power switch in the switch enclosure.

The beneficial effects of the utility model：

1）Weight freely falling body principle is make use of, the landing of peening hammer is controlled by electromagnetic system, cause the moment of spinal cord Collision injury, reduces the error of human factor；

2）Accurate adjustment hitting power, hitting power is adjusted by adjusting strike height, can hand wheel accurately adjust height, Minimum adjustment height is 0.01mm；

3）The utility model wide adaptation range, can be used for the big animal such as dog, pig, monkey, cat, rabbit, by changing different model Attacking head come realize different animal species spinal cord injury model make；

4）Peening hammer upper end is made up of metallic iron, lower end of metallic copper material, lower heavy light guarantee peening hammer vertical landing, And automatically springed open after causing moment collision injury, it is to avoid cause two-hit；

5）It is easy to operate, various dimensions regulation and control, horizontal/vertical/sagittal plane can be carried out, and quick and precisely position, quantitatively beat Hit；

6）Easily maintenance, main frame is mainly made up of stainless steel material, long with non-corrosive, it is to avoid error；Overall weight is appropriate, Movement can be easy to；Aufbauprinciple science, good stability；Normalizing operation makes the repeatable stronger of experiment, and this instrument is applied to Various large-scale experiment animal spinal cords clash into the making of wound model, are adapted to laboratory requirements at different levels, can be mass, with good Scientific research value and social economic value.

Brief description of the drawings

In order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art, below will be to embodiment Needed for the accompanying drawing to be used be briefly described, it should be apparent that, drawings in the following description are only of the present utility model Some embodiments, for those of ordinary skill in the art, on the premise of not paying creative work, can also be according to this A little accompanying drawings obtain other accompanying drawings.

Fig. 1 is the big animal spinal cord moment impact damage model modeling beating device according to the utility model embodiment Front view；

Fig. 2 is the top view of the level(l)ing device according to the utility model embodiment；

Fig. 3 is the top view of plane fine-tuning device according to the utility model embodiment and pedestal；

Fig. 4 is the sectional view of the aiming percussion device according to the utility model embodiment.

In figure：

1st, base；2nd, adjusting nut；3rd, pillar；4th, switch enclosure；5th, connecting plate；6th, lead column；7th, screw mandrel；8th, slide plate；9、 Level(l)ing device；10th, counter；11st, handwheel；12nd, fixed connecting rod；13rd, translation connecting rod；14th, plane fine-tuning device；15th, take aim at Quasi- percussion device；16th, HeiFin device；17th, substrate one；18th, X is to level meter；19th, Y-direction level meter；20th, substrate two；21、X To adjusting means；22nd, Y-direction adjusting means；23rd, pedestal；24th, laser fixed seat；25th, laser；26th, seat centering spheroid；27、 Magnetic coil；28th, magnetic plate；29th, peening hammer passage；30th, peening hammer；31st, sight hole.

Specific embodiment

Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole Embodiment.Based on the embodiment in the utility model, the every other embodiment that those of ordinary skill in the art are obtained all belongs to In the scope of the utility model protection.

As shown in figure 1, a kind of big animal spinal cord moment impact damage model according to the utility model embodiment is built Mould beating device, including base 1, the base 1 are provided with some pillars 3 and some adjusting nuts 2, and the pillar 3 is provided with Screw mandrel 7 and some lead columns 6, the screw mandrel 7 and lead column 6 are fixedly connected with level(l)ing device 9, and the screw mandrel 7 is slided The counter 10 located at the top of level(l)ing device 9 is connected with, the screw mandrel 7 is fixedly connected with located at the top of counter 10 Handwheel 11；The screw mandrel 7 also slidably connects the slide plate 8 located at the lower section of level(l)ing device 9, and the slide plate 8 is fixed and connected Fixed connecting rod 12 is connected to, the fixed connecting rod 12 is rotatably connected to translation connecting rod 13, and the translation connecting rod 13 is rotatably connected to flat Face micromatic setting 14, the plane fine-tuning device 14 is provided with aiming percussion device 15, and the aiming percussion device 15 is provided with HeiFin device 16, the HeiFin device 16 is connected with the plane fine-tuning device 14；A piece right side for the pillar 3 Switch enclosure 4 is fixedly connected with, the switch enclosure 4 is connected by wire with the aiming percussion device 15.

Wherein, the lower end connect base 1 of the pillar 3, upper end connection lead column 6, it is therefore an objective to make pillar 3 perpendicular to Horizon Line；The fixed connecting rod 12 is fixedly connected with slide plate 8, and fixed connecting rod 12 is vertical with lead column 6, that is, fix connecting rod 12 and horizon Parallel, translation connecting rod 13 is rotated with fixed connecting rod 12 and is connected, and can horizontally rotate regulation strike position, and fixed connecting rod 12 connects with translation The connection design of bar 13 also ensure that and move in parallel in the horizontal plane.

As shown in Fig. 2 the level(l)ing device 9 includes substrate 1, the front side of the substrate 1 is provided with X to level Instrument 18, the left side of the substrate 1 is provided with Y-direction level meter 19.

As shown in Figure 3-4, the plane fine-tuning device 14 includes substrate 2 20, and X is slidably connected on the substrate 2 20 To micromatic setting 21, the X sets to Y-direction micromatic setting 22 is slidably connected on micromatic setting 21 on the Y-direction micromatic setting 22 There is aiming percussion device 15.

Wherein, the aiming percussion device 15 includes pedestal 23, and the pedestal 23 is provided with laser fixed seat 24, described Laser fixed seat 24 is provided with some adjusting screws, the laser fixed seat 24 and is provided with laser 25, the pedestal 23 Seat centering spheroid 26 is inside provided with, the seat centering spheroid 26 is provided with through hole, and one end of the laser 25 passes through the through hole It is fixedly connected with the seat centering body of spheroid 26, the seat centering spheroid 26 is fixedly connected with hollow magnetic force and fills by the through hole Put, the hollow magnetic means is connected with peening hammer device；The laser 25 is by wire and in the switch enclosure 4 Laser switch is connected, and the hollow magnetic means is connected by wire with the electromagnetic switch in the switch enclosure 4.

Wherein, the hollow magnetic means includes magnetic coil 27, and the magnetic coil 27 is connected with magnetic plate 28.Its In, the peening hammer device includes slidably connecting peening hammer 30 in peening hammer passage 29, the peening hammer passage 29, described to beat Sight hole 31 is provided with hammer 30.Wherein, the HeiFin device 16 includes the support on the outside of hollow magnetic means, institute State support and be provided with adjusting screw.Wherein, it is additionally provided with power switch in the switch enclosure 4.

Wherein, the aiming percussion device 15 includes seat centering spheroid 26, and the seat centering upper end of spheroid 26 is fixed with laser Seat 24 is fixedly connected, and lower end is fixedly connected with hollow magnetic means, and seat centering spheroid 26 is fallen within cone row face, is hit due to aiming at The own wt of device 15 makes aiming percussion device 15 automatic freely sagging i.e. vertical with horizon, and with the fixation of four direction Screw fixes the seat centering spheroid 26 for aiming at percussion device 15, so that the necessary condition of the freely falling body of peening hammer 30 set up；Its In, the aiming percussion device 15 is parallel with pillar 3 and is each perpendicular to horizon, and fixed connecting rod and translation connecting rod are each parallel to ground Horizontal line；Wherein, the lower end of the peening hammer 30 is made up of metallic copper material, and upper end is made up of metal iron material, lower heavy light guarantee One layer of chromium is crossed outside the vertical landing of peening hammer 30, peening hammer 30, prevents iron from getting rusty, it is ensured that the mass of peening hammer 30 is accurately unchanged；Its In, attacking head laser post goes out bore dia 1mm, is overlapped with predetermined striking point through the laser spots portalled, it can be ensured that precisely strike is fixed Position；Wherein, the plane fine-tuning device 14 pairs aims at percussion device 15 and is finely adjusted, and the peening hammer 30 is to masterplate target spot（For Concentric circles figure, concentric circles figure maximum gauge is consistent with attacking head diameter）Carry out examination to beat, hit aiming at according to strike result Device 15 carries out vertical detection again, it is ensured that strike station accuracy.

According to the workflow bag of big animal spinal cord moment impact damage model modeling beating device described in the utility model Include：

First, the overall condition of big animal spinal cord moment impact damage model modeling beating device is first checked for, it is ensured that each connection Place's screw tightening；

2nd, big animal spinal cord moment impact damage model modeling beating device is stood on into level ground, at this moment can be appreciated that Y-direction Level meter 19 and X are in level meter centre position to the vacuole of level meter 18（If ground is not level, can be by rotation The adjusting nut 2 of base carrys out adjustment, and so big animal spinal cord moment impact damage model modeling beating device just can be not Same ground is operated)；

3rd, Beating Strength is adjusted：By shaking handwheel 11, decline peening hammer 30 close to target spot, then reversely shake handwheel 11 are raised up to corresponding height（Strike height is shown by hitting height computer 10）；According to the hitting dynamics of requirement of experiment, Adjustment strike height is capable of achieving the spinal cord injury model of corresponding hitting dynamics.Different damages can be hit out according to different height The spinal cord injury model of degree；

4th, striking point is accurately positioned：After laser 25 is powered, light beam is passed from the sight hole 31 in peening hammer 30, regulation Percussion device 15 is aimed at, laser beam is irradiated to predetermined target spot, it is fixed to aim at percussion device 15, now carry out examination and beat, if strike Head can not vertically hit target spot, can be by adjusting plane fine-tuning device 14, until target spot is arrived in attacking head strike（Applied in attacking head A small amount of ink paste is smeared, whole circular strike head all touch target spot for level）；

5th, strike is implemented：Confirm laser switch, the setting electric wire of electromagnetic switch（line out）The state opened（Prevent Artificial origin touches big animal spinal cord moment impact damage model modeling beating device and causes to hit deviation）, now peening hammer 30 （20g, it is aseptic）By magnetic plate 28 attract fix, laser beam pass the laser spots after peening hammer 30 with hit target spot it is Chong Die, again Confirm strike height, rotation top handwheel regulates height about 11（Different strike degree regulation height are different, hit scope 20-640g cm, precision is 0.01mm）, electromagnetic switch is closed, peening hammer 30 loses magnetic plate 28 and attracts free falling accurately to beat Hit on target spot, cause spinal cord collision injury, remove big animal spinal cord moment impact damage model modeling beating device, completion was hit Journey.

The utility model is constant according to gravitional force formula W=mgh, g, therefore according to the quality of peening hammer 30（g）It is multiplied by certainly By the height of falling bodies（cm）The result for obtaining carrys out the index as strike degree.That is " GCM methods ".The height that adjustment peening hammer 30 falls Degree can produce different damage forces, make the spinal cord contusion model of Injured level.Hitting dynamics scope（20-640）G cm, Strike degree of precision is 0.01mm, and the weight configuration of peening hammer 30 is 20g, then hitting power accuracy is 0.02g cm；Reach 500g cm can cause the double lower limb completeness of dog to paralyse.The utility model wide adaptation range, can be used for dog, pig, monkey, cat, rabbit Etc. the preparation of various big animal spinal cord damage models.

Preferred embodiment of the present utility model is the foregoing is only, is not used to limit the utility model, it is all at this Within the spirit and principle of utility model, any modification, equivalent substitution and improvements made etc. should be included in the utility model Protection domain within.

Claims (8)

1. a kind of big animal spinal cord moment impact damage model modeling beating device, it is characterised in that including base（1）, the bottom Seat（1）It is provided with some pillars（3）With some adjusting nuts（2）, the pillar（3）It is provided with connecting plate（5）, the connection Plate（5）It is provided with screw mandrel（7）With some lead columns（6）, the screw mandrel（7）And lead column（6）It is fixedly connected with Level tune dress Put（9）, the screw mandrel（7）Slidably connect located at level(l)ing device（9）The counter of top（10）, the screw mandrel（7）Gu Surely it is connected with located at counter（10）Top handwheel（11）；The screw mandrel（7）Also slidably connect located at Level tune dress Put（9）The slide plate of lower section（8）, the slide plate（8）It is fixedly connected with fixed connecting rod（12）, the fixed connecting rod（12）Rotate connection There is translation connecting rod（13）, the translation connecting rod（13）It is rotatably connected to plane fine-tuning device（14）, the plane fine-tuning device （14）It is provided with aiming percussion device（15）, the aiming percussion device（15）It is provided with HeiFin device（16）, it is described to hang down Straight micromatic setting（16）With the plane fine-tuning device（14）Connection；Wherein one pillar（3）Right side be fixedly connected with switch Box（4）, the switch enclosure（4）By wire and the aiming percussion device（15）Connection.

2. big animal spinal cord moment impact damage model modeling beating device according to claim 1, it is characterised in that described Level(l)ing device（9）Including substrate one（17）, the substrate one（17）Front side be provided with X to level meter（18）, the substrate One（17）Left side be provided with Y-direction level meter（19）.

3. big animal spinal cord moment impact damage model modeling beating device according to claim 2, it is characterised in that described Plane fine-tuning device（14）Including substrate two（20）, the substrate two（20）On slidably connect X to micromatic setting（21）, it is described X is to micromatic setting（21）On slidably connect Y-direction micromatic setting（22）, the aiming percussion device（15）It is located at the Y-direction micro- Adjust device（22）On.

4. big animal spinal cord moment impact damage model modeling beating device according to claim 3, it is characterised in that described Aim at percussion device（15）Including pedestal（23）, the pedestal（23）It is provided with laser fixed seat（24）, the laser consolidate Reservation（24）It is provided with some adjusting screws, the laser fixed seat（24）Inside it is provided with laser（25）, the pedestal（23） Inside it is provided with seat centering spheroid（26）, the seat centering spheroid（26）It is provided with through hole, the laser（25）One end pass through institute Through hole is stated with seat centering spheroid（26）It is fixedly connected, the seat centering spheroid（26）It is fixedly connected by the through hole free Heart magnetic means, the hollow magnetic means is connected with peening hammer device；The laser（25）By wire and located at described Switch enclosure（4）Interior laser switch connection, the hollow magnetic means is by wire and is located at the switch enclosure（4）Interior electricity Magnetic switch is connected.

5. big animal spinal cord moment impact damage model modeling beating device according to claim 4, it is characterised in that described Hollow magnetic means includes magnetic coil（27）, the magnetic coil（27）It is connected with magnetic plate（28）.

6. big animal spinal cord moment impact damage model modeling beating device according to claim 5, it is characterised in that described Peening hammer device includes peening hammer passage（29）, the peening hammer passage（29）Slidably connect peening hammer（30）, the strike Hammer（30）Inside it is provided with sight hole（31）.

7. big animal spinal cord moment impact damage model modeling beating device according to claim 6, it is characterised in that described HeiFin device（16）Including the support on the outside of the hollow magnetic means, the support is provided with adjusting screw.

8. big animal spinal cord moment impact damage model modeling beating device according to claim 1, it is characterised in that described Switch enclosure（4）Inside it is provided with power switch.