CN206102780U - Aspherical intraocular lens - Google Patents
Aspherical intraocular lens Download PDFInfo
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- CN206102780U CN206102780U CN201620522067.6U CN201620522067U CN206102780U CN 206102780 U CN206102780 U CN 206102780U CN 201620522067 U CN201620522067 U CN 201620522067U CN 206102780 U CN206102780 U CN 206102780U
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- artificial intraocular
- intraocular lensess
- lensess
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Abstract
The utility model relates to an aspherical intraocular lens. Specifically, intraocular lens including have optical surface optical portion and with the several button loop that optical portion is connected. Optical portion's optical surface is the aspheric surface, is wherein assembling light incident under 5 millimeters effective optics apertures through the cornea is refractive behind the intraocular lens, does the spherical aberration that intraocular lens appears do 0.1 -0 mu m.
Description
Technical field
This utility model is related to a kind of aspheric intraocular lens, particularly to a kind of weak aspheric intraocular lens.
Background technology
Background description provided herein is used to generally introduce background content of the present utility model.In this section, institute is old
The content stated may be constituted or may not constitute prior art.
Artificial intraocular lensess（IOL）It is a kind of artificial lens that can be implanted into ophthalmic, which is used to replace human eye itself because cataract
Disease and the natural crystal that becomes cloudy, or for refractive surgery correcting the vision of human eye deviation.
Existing artificial intraocular lensess' majority is fabricated from a flexible material, because which is generally folded or crimps reducing in operation
Otch after its area for example, by 2-3 millimeters is implanted into ophthalmic, therefore also known as collapsible crystal.Artificial intraocular lensess are in implanted human eye
The relative position in pouch is maintained by supporting the interaction force between button loop and human eye pouch afterwards.Collapsible crystal enters pleasing to the eye
Energy Automatic-expanding after interior, thus the material of collapsible crystal is elastomer mostly.Currently used for the material master of folded iol
Silica gel to be divided into, hydrogel, hydrophilic acrylate and hydrophobic acrylic acid's ester, wherein hydrophobic acrylic acid's ester is because of its refractive power
Index is of a relatively high and the preferably but current most popular artificial crystal material of the characteristic opened in performing the operation.
The opticator of artificial intraocular lensess collectively constitutes dioptric system with the cornea of human eye, and in the dioptric system, spherical aberration is
Affect the most important factor of image quality.In general, the natural crystal that the cornea of people has positive spherical aberration, people has negative ball
Difference, the cornea and natural crystal mutual balanced action with spherical aberration in human eye dioptric system of usual people.In most cases
The sphere artificial intraocular lensess with positive spherical aberration being implanted in human eye after cataract operation can increase the positive spherical aberration of whole vision systems,
The positive spherical aberration of increase can make the image quality decrease on retina, particularly even more so in the case of pupil insufficient light.
Accordingly, it is desired to provide a kind of artificial intraocular lensess, with the natural crystal that can weaken human eye it is replaced after because of positive spherical aberration liter
Caused by high, image quality declines, and so as to set up new vision systems, improves image quality.
Utility model content
One of the purpose of this utility model is to provide a kind of aspheric intraocular lens, and which can make up cornea and just cause
Spherical aberration, so as to the contrast of image quality when improving that for example pupil is larger under dark surrounding enviroment.
Another object of the present utility model is to provide a kind of weak aspheric artificial intraocular lensess, and which can aid in eyes and obtains
More preferable depth of focus is obtained, making aspheric faceted crystal that eccentric and/or inclination is placed to eyeglass has higher tolerance tolerance, weakens aspheric surface
The increase of the higher order aberratons that crystal causes because of placement bias and/or when inclining is so as to the phenomenon of the too fast decline of whole image quality.
According to one side of the present utility model, there is provided a kind of artificial intraocular lensess, the artificial intraocular lensess include：
Opticator with optical surface；
The several buttons loop being connected with the opticator；
Wherein, the optical surface of the opticator is aspheric surface, and wherein the refraction of Jing corneas convergence light 5
Under millimeter effectively optical aperture after the incident artificial intraocular lensess, the spherical aberration that the artificial intraocular lensess are presented is -0.1-0 μm.
According to another aspect of the present utility model, the artificial intraocular lensess have the clear aperature more than 6.0 millimeters.The opposing party
Face, the artificial intraocular lensess are with 6.5 millimeters of clear aperature.
According to another aspect of the present utility model, the artificial intraocular lensess provide the diopter from 6.0D to 34.0D.
According to another aspect of the present utility model, the artificial intraocular lensess are made using crosslinked polyolefin materials.On the other hand,
The artificial intraocular lensess are made using the crosslinked polyolefin materials that light refractive index is more than 1.51 and Abbe number is more than 49.5.Another side
Face, the artificial intraocular lensess are made up of 50 crosslinked polyolefin materials of 1.515 and Abbe number using light refractive index.
According to another aspect of the present utility model, the optical surface includes front optical surface and rear optical surface, wherein
Front optical surface and/or rear optical surface are aspheric surface.
According to another aspect of the present utility model, the optical surface includes front optical surface and rear optical surface, wherein
Front optical surface and rear optical surface are combined as aspheric surface with certain proportion.
According to another aspect of the present utility model, the spherical aberration is optimized by the optical modeling to the optical surface
Realize, wherein the optical modeling include the selected shape factor, the curvature of centre of optical surface, the center thickness of optical surface,
Edge thickness, focus incident light degree, effective optical aperture, paraxial smooth focus point, distal shaft light focus point, the light refraction of material
Rate and dispersive power.
According to another aspect of the present utility model, the optics edge thickness described in optimization process, focus incident light degree,
Effectively optical aperture, paraxial smooth focus point, distal shaft light focus point, the light refractive index of material and dispersive power keeps constant.
According to another aspect of the present utility model, the form factor is between 0.1-0.75.On the other hand, it is described
Form factor is between 0.16-0.38.
According to another further aspect of the present utility model, the expression formula of the optical modeling of the optical surface is：S(r) =
Wherein：C is the curvature of the optical surface；K is the constant of the cone；A1, A2, A3... are order aspherical systems
Number.
According to another further aspect of the present utility model, the spherical aberration is -0.05 μm, wherein k -91.774 to -9.583 it
Between, A1=A2=0, A3 is between 5.867E-05 to 8.059E-05.
According to another further aspect of the present utility model, the spherical aberration is -0.05 μm, wherein k=0, A1=0, and A2 is in 1.225E-
04 between 4.547E-04, and A3 is between -5.062E-06 to -1.083E-06.
According to another further aspect of the present utility model, the spherical aberration is -0.1 μm, wherein k -115.376 to -10.666 it
Between, between 1.865E-04 to 2.220E-04, A3 is between -8.928E-07 to -1.793E-06 for A1=0, A2.
According to another further aspect of the present utility model, the spherical aberration is 0 μm, wherein k between -86.841 to -7.413,
A1=A2=A3=0。
According to another further aspect of the present utility model, the excursion of the position of the optics secondary principal plane of the artificial intraocular lensess
In 0.054 millimeter.
The further scope of application will become apparent from the description provided herein.It should be understood that this description and particular case
Son is only intended to illustrate purpose, and is not intended to limit scope of the present utility model.
Description of the drawings
The characteristics of this utility model and advantage will from below in conjunction with the accompanying drawings to preferred implementation of the present utility model and
Become apparent in the detailed description of other embodiment.In the accompanying drawings, wherein：
Fig. 1 is the schematic diagram of the artificial intraocular lensess fastened with a rope, string, etc. with opticator and several supports.
Fig. 2 is the composition schematic diagram of the opticator of artificial intraocular lensess.
Fig. 3 A are shown respectively impact of two kinds of different spherical aberration compensation designs to depth of focus with Fig. 3 B.
Fig. 4 A illustrate that lens tilt and bias are right in the case where the design of numerous values negative spherical aberration and weak negative spherical aberration are designed respectively
The impact of image quality.
Fig. 4 B are illustrated respectively when the design of numerous values negative spherical aberration and weak negative spherical aberration are designed under the influence of eyeglass set error
The comparison of MTF slippages.
Fig. 5 A illustrate light refractive index for the impact of MTF.
Fig. 5 B and Fig. 5 C are shown respectively the eyeglass schematic diagram manufactured by the material using different light refractive indexes.
Fig. 6 A and 6B respectively schematically illustrate axially and also laterally aberration.
Fig. 7 illustrates different dispersive power materials for the impact of eyeglass aberration.
Fig. 8 illustrates different dispersive power materials for the impact of white light imaging quality.
Fig. 9 A and Fig. 9 B illustrate veiling glare for the impact of image quality.
Fig. 9 C and Fig. 9 D illustrate that the artificial intraocular lensess edge under different clear aperatures reflects the situation of veiling glare.
Figure 10 illustrates impact of the set deviation of artificial intraocular lensess to image quality.
Figure 11 illustrates clear aperature for the impact of optical transfer function.
Figure 12 schematically shows the relation of spherical aberration and form factor.
Figure 13 illustrates an example according to form factor of the present utility model distribution.
Figure 14 illustrates another example according to form factor of the present utility model distribution.
Figure 15 illustrates the another example according to form factor of the present utility model distribution.
Figure 16 illustrates the another example according to form factor of the present utility model distribution.
Figure 17 illustrates the change according to optics secondary principal plane position of the present utility model.
Specific embodiment
Explained below is substantially only exemplary rather than the restriction to the application.
Referring to Fig. 1, artificial intraocular lensess generally include a circular opticator or optical body 1 and coupled several
Support button loop 2.Although two are illustrate only in figure supports button loop, it will be recognized to those skilled in the art that the number of button loop 2 can be more than
2, such as 3,4 or more etc..Referring to Fig. 2, opticator 1 has front optical surface 3 and rear optical surface 4, and light
The center thickness reference 5 of the department of the Chinese Academy of Sciences point is represented, edge thickness reference 6 is represented and 7 table of diameter reference
Show.
According to Fig. 2, total diopter of opticator is calculated as follows：
=1+2- (t/N_iol)12 （1）
1=(N_iol-N_medium)/R1（2）
2=(N_iol-N_medium)/R2（3）
Wherein：Total diopter of IOL is represented,1 diopter for representing front optical surface,Optical surface after 2 representatives
Diopter, t represent center thickness, and N_iol is the refractive index of optical material, and N_medium is the liquid environment in human eye（Aqueous humor
Environment）Light refractive index, be usually used 1.336 as standard figures, R1 represent before optical surface radius of curvature, R2 generations
The radius of curvature of optical surface after table.
As it was previously stated, spherical aberration is to affect the most important factor of image quality.Therefore, in order to obtain preferably visual performance,
Artificial intraocular lensess make every effort to the refractive power and aberration characteristic for recovering natural human eye crystal as much as possible.As the cornea of people has positive ball
Difference, the natural crystal of people has negative spherical aberration, so, substitute people it is natural crystal, and the cornea of human eye collectively constitute human eye and bend
The artificial intraocular lensess of photosystem need to provide negative spherical aberration, to make up the positive spherical aberration of cornea initiation.
The inventors discovered that, Jing corneas refraction convergence light under 5 millimeters of effective optical apertures incidence artificial intraocular lensess
The afterwards spherical aberration are presented by artificial intraocular lensess not only can increase the depth of focus of imaging when being -0.1-0 μm, and can weaken aspheric surface
Artificial intraocular lensess cause whole image quality because placement location increase that is eccentric and/or inclining caused higher order aberratons occurs
Decline too fast phenomenon.
Generally, cornea has the refraction of about 42D to light, and it is big that directional light converges in natural crystal rear Jing after cornea refraction
At about 27-29 millimeters, and the spherical aberration of eye cornea substantially distribution, between 0-0.32 μm, average spherical aberration is in 0.21 μ
m.Here, artificial intraocular lensess of the spherical aberration design between -0.3--0.2 μ ms are referred to as numerous values negative spherical aberration crystal, spherical aberration design
Artificial intraocular lensess between -0.2--0.1 μm are referred to as average magnitude negative spherical aberration crystal, and spherical aberration is designed at -0.1-0 μm
Between artificial intraocular lensess be referred to as little value（It is weak）Negative spherical aberration crystal.Compared to current numerous values and the design of average magnitude negative spherical aberration
Speech（As spherical aberration is less than -0.2 μm）Situation, the present invention weak negative spherical aberration artificial intraocular lensess implantation human eye after, cornea can be offset
A part of positive spherical aberration, make total spherical aberration of whole eye be close to zero but slightly be in positive spherical aberration.This on whole opthalmic optics are imaged have and prolongs
The effect of exhibition depth of focus.Referring to Fig. 3 A and Fig. 3 B, under the different spherical aberration values depth of focus effect obtained by people's eye is shown.It is artificial brilliant
Body A negative spherical aberrations of the design with numerous values, after implantation eyes, the positive spherical aberration of cornea is completely counterbalanced by by which, i.e., 100% compensation angle
The positive spherical aberration (referring to upper row's image) of film.Artificial intraocular lensess B designs are with little value（It is weak）Negative spherical aberration, after implantation eyes, which is only
A part of positive spherical aberration of cornea is offset, makes total spherical aberration of whole eye be maintained at 0.1 μm（Referring to lower row's image）.The simulation of the figure shows
Show the crystal with little value negative spherical aberration（Crystal B）At least better than numerous values negative spherical aberration crystal 0.5D on depth of focus extends（Quite
In 50 degree of degree of focus）.
As it was previously stated, the inventors discovered that the crystal phase ratio designed with numerous values negative spherical aberration, is set using little value negative spherical aberration
The crystal of meter can make aspheric faceted crystal place inclination and bias to crystal higher tolerance tolerance.As known in the art
, the objective description of lens optical image quality typically adopts optical-modulation transfer function MTF（Modulation Transfer
Function）Quantized value.MTF characterizes transmission of the picture contrast in different space frequency from thing to picture.MTF values are got over
Height, crystal（Eyeglass）Image quality it is better.Referring to Fig. 4 A and 4B, respectively illustrate two kinds of different spherical aberration compensation modes for
The impact of image quality.In figures 4 a and 4b, negative spherical aberration of the crystal A designs with numerous values, after implantation eyes, by cornea just
Spherical aberration is completely low to disappear；Crystal B designs after implantation eyes, are only offset part cornea positive spherical aberration, and are made whole with little value negative spherical aberration
Total spherical aberration of eye is also maintained at 0.1 μm.Fig. 4 A show two kinds of crystal respectively without set error and having MTF under set error condition
Decline.In Figure 4 A, crystal A is bold curve system, and crystal B is fine alcoholic fermented preparation linear system, and solid line represents crystal without inclination and nothing
It is eccentric（Normotopia）Set situation, dotted line represents that crystal inclines 2.6 degree and eccentric 0.4 millimeter set in average set error
Situation.Generally, artificial intraocular lensess after implantation pouch, average tilt angle is 2.6 degree, average set it is eccentric for 0.4 in the least
Rice.It can be seen that little value（It is weak）Negative spherical aberration crystal（Crystal B）Inclining 2.6 degree and eccentric 0.4 millimeter set feelings
Under condition, MTF has no and is decreased obviously.Conversely, numerous values negative spherical aberration crystal（Crystal A）Show in the case of identical set substantially
MTF decline.Used as further comparing, Fig. 4 B directly illustrate crystal A that the design of numerous values negative spherical aberration is respectively adopted and weak negative
The crystal B of spherical aberration design is in usual set error（Incline 2.6 degree and 0.4 millimeter of bias）Under the influence of optical transfer function each
The decline of individual spatial frequency., it is apparent that the MTF tools of crystal A significantly decrease from 4B, and the MTF of crystal B has no
It is decreased obviously.From here it can be clearly seen that the weak negative spherical aberration design of the artificial intraocular lensess of the application crystal is placed incline and
It is eccentric that there is higher tolerance, so as to there is significant advantage with the crystal phase of numerous values negative spherical aberration ratio.
In order to further improve artificial intraocular lensess（IOL）The superiority and stability of optical property, this Shen after implantation human eye
Please utilize high index of refraction and low dispersion（The dispersion of material is the ginseng for describing the different refractivity that material is shown at different wavelengths
Number, which is defined by Abbe number, and wherein high Abbe number corresponds to low dispersion, and low Abbe number corresponds to high dispersion）Bio-compatible
Material, such as bio-compatible material of the Abbe number with the light refractive index more than 1.51 and more than 49.5, such as in patent
Crosslinked polyolefin materials disclosed in document CN200880124361.X.The patent documentation is incorporated into this by reference of text
In.With the crystal phase ratio of the design of material that 1.5 are less than using low-refraction, the application is using the crosslinked polyolefin materials（Folding
Rate is penetrated more than 1.51 and Abbe number is more than 49.5）The crystal of design can have less surface curvature, less so as to present
Primary sphere positive spherical aberration.Referring to Fig. 5 A, Fig. 5 B and Fig. 5 C, wherein, crystal A represents that the conventional silicon that light refractive index is 1.427 coagulates
The artificial intraocular lensess of glue material manufacture, crystal B represent the artificial crystalline substance of the crosslinked polyolefin materials manufacture that light refractive index is 1.515
Body, shows in same optical power and form factor（Will be explained below）In the case of material light refractive index for artificial
The impact of the characteristic of crystal.Find out from Fig. 5 A, the MTF values of the artificial intraocular lensess manufactured using crosslinked polyolefin materials are higher, from
And there is preferable image quality.From Fig. 5 B and Fig. 5 C and table one as can be seen that with artificial brilliant made by high-index material
Body B has less volume than artificial intraocular lensess A made by low-refraction（Also less area of section）, because opticator center
Thickness is directly proportional to surface curvature.Simultaneously from table one it can also be seen that identical diopter（Focal power）When, if optics edge
Thickness is identical, crystal made by high-index material（Refractive Index of Material used in this application is 1.515）Make than low-refraction
The center thickness of crystal want thin by 44%, and small volume 39%.Can the volume of crystal is determined make crystal volume enough to little with logical
Cross syringe and enter human eye, which determine the size of operative incision.It is advantageous for using the artificial intraocular lensess of high-index material little
One key parameter of incision surgery.
Table one
。
For the optical design of low-index material, there is higher primary positive ball as surface curvature is larger
Difference, thus image quality is less than the design based on high-index material.In addition, for small radius surfaces（High-index material）
Crystal for, by crystal bias and incline caused higher order aberratons increase phenomenon can be than deep camber surface（Low-refraction
Material）Crystal it is weaker, therefore image quality stability can get well.I.e. the artificial intraocular lensess of high-index material are designed in optics set
Under error, which is as artificial intraocular lensess' design of matter stability better than low-index material.In addition with using low Abbe（For example
Less than 40）Design of material crystal phase ratio, the application use the crosslinked polyolefin materials（Abbe number is more than 49.5）Design
Crystal there is less axially and longitudinally aberration.Axial chromatic aberration refers to that the focus point of different wave length is different, referring to Fig. 6 A, spectrum
C lines, d lines, F lines have different focus points；Longitudinal chromatic aberration refers to that the lateral magnification of different wave length is different, referring to Fig. 6 B, light
Spectrum C lines, d lines, F lines have different lateral magnifications, and in Fig. 6 A, 6B, Z-axis represents optical axis, also represents light propagation side
To；Stop represents restriction clear aperature, or claims to limit pupil.Referring to Fig. 7, the different dispersive power materials under same design are shown
Material for the impact of crystal aberration, wherein crystal A be using Abbe number be 37 high chromatic dispersion material made by artificial intraocular lensess, crystal
B be using Abbe number be 50 low chromatic dispersion material made by artificial intraocular lensess.It is apparent that used in this application with high Abbe number value
（Equal to 50）Crosslinked polyolefin materials be substantially better than in the focus proliferation caused by aberration it is common with low Abbe number
Value（Here it is 37）Hydrophobic acrylic acid's ester material.It is 21.0D and visible spectrum that table two is given in focal power
In the case of for 486nm-656nm, the application is using with high Abbe number value（Equal to 50）Crosslinked polyolefin materials design people
Work crystal is with commonly used in the art with low Abbe（Here it is 37）Hydrophobic acrylic acid's ester material design people
The comparison of work crystal.As can be seen from Table II, the people that the application is designed using the crosslinked polyolefin materials with high Abbe number value
The focus movement ultimate range of work crystal and maximum fuzzy spot diameter are far smaller than commonly used in the art with low Abbe number
The artificial intraocular lensess of hydrophobic acrylic acid's ester material design of value, so as to greatly reduce because the focus that aberration causes spreads, improve
Image quality.
Table two
。
And, for same aspheric design, the artificial crystalline substance designed using the crosslinked polyolefin materials of high Abbe number value
Body can reduce high-order ball aberration, thus overall image quality can be better than the artificial crystalline substance using low Abbe design of material under white light
Body.Referring to Fig. 8, show that different dispersive power materials are for the impact of white light imaging quality under same design.Wherein, crystal A
It is that the application is used with high Abbe number value（Equal to 50）Crosslinked polyolefin materials design artificial intraocular lensess, crystal B be ability
Domain be usually used with low Abbe（Equal to 37）Hydrophobic acrylic acid's ester material design artificial intraocular lensess.It is aobvious and easy
See, the application is using with high Abbe number value（Equal to 50）Crosslinked polyolefin materials design artificial intraocular lensess have it is higher
MTF values, namely preferably image quality, so that the weak negative spherical aberration Heterosis of the application artificial intraocular lensess obtain more abundant.
Due to the high elasticity that extends of above-mentioned crosslinked polyolefin materials, the present inventor can design optical body diameter by which
（That is clear aperature）Artificial intraocular lensess more than 6.0 millimeters such as 6.5 millimeters.6.0 millimeters are less than with current optical body diameter
Artificial intraocular lensess（IOL）Compare, natural crystal of the artificial intraocular lensess with 6.5 millimeters of optical body diameters closer to people, to crystal light
Learn image quality more helpful.On the one hand, it can substantially reduce the probability that the unnecessary edge of eyeglass reflects veiling glare.Such as ability
Personnel are understood for field technique, and veiling glare can directly slacken the contrast of imaging, so as to reduce picture quality（Referring to Fig. 9 A and figure
9B）.This is because after artificial intraocular lensess' implantation human eye, there is gap between pupil and crystal, the incident illumination of wide-angle is possible to
Up to crystal edge so as to causing the reflection of edge veiling glare.This reflected light is referred to as non-imaged light, and such non-imaged light beam is not only
Imaging is not involved in, interference effect is played to image quality on the contrary.The non-imaged light can directly reduce picture contrast in hour, and
One emergency light reflex arc is formed on the retina can when big.Referring to Fig. 9 C and Fig. 9 D, show artificial under different clear aperatures
Crystal edge reflects the situation of veiling glare.The incident illumination to same angle, optical body diameter are can be seen that from Fig. 9 C and Fig. 9 D
Have there is edge and have reflected spuious optical phenomenon in artificial intraocular lensess less than 6 millimeters, and the artificial intraocular lensess of a diameter of 6.5 millimeters of optical body do not have
There is any edge reflex.This illustrates that the crystal of big optical body diameter can reduce the probability that skew ray reaches crystal edge,
So as to effectively eliminate or weaken edge veiling glare reflection.On the other hand, the artificial intraocular lensess of big optical body diameter can also improve eyeglass
The eccentric and inclined ability of resistance to set.As it was previously stated, set deviation of the eyeglass in pouch can cause lens imaging quality
Decline, referring further to Figure 10, there is shown with without set error（Without inclination and without acceptance of persons）Artificial intraocular lensess A ratios under state are average
Set error（Incline 2.6 degree and 0.4 millimeter of bias）Artificial intraocular lensess B under state has bigger MTF values, this explanation set
Deviation causes the decline of lens imaging quality.Figure 11 shows optic diameter for the impact of optical transfer function.In Figure 11
In, crystal A represents artificial intraocular lensess of the optic diameter being under average set error state less than 6.0 millimeters, and crystal B is represented
The optic diameter being under average set error state is 6.5 millimeters of artificial intraocular lensess.As can be seen from Figure 11 have big
The artificial intraocular lensess of optic diameter can improve the eccentric and inclined ability of the resistance to set of eyeglass.
As it is known in the art, in order to be beneficial to artificial intraocular lensess（IOL）Design, need using relying on substantially simplified human eye
The theoretical eye models of construction, such as Liou-Brennan eye models.As it was previously stated, the design object of artificial intraocular lensess be which can
Image quality similar to crystal of human eye is provided.Therefore, the design of the application artificial intraocular lensess is that its negative spherical aberration for providing can
The positive spherical aberration of cornea or the offer of model eye is made up to improve image quality.
Referring back to Fig. 2, the opticator 1 of artificial intraocular lensess has front optical surface 3 and rear optical surface 4.Therefore, this Shen
Please pass through to design front optical surface 3, rear optical surface 4 or front optical surface 3 and the rear optical surface 4 of artificial intraocular lensess
Both come with desired aspheric region feature so as to realizing the desired imaging effect of artificial intraocular lensess.
Usually, the aspheric region feature of the optical surface of artificial intraocular lensess can be represented by various expression formulas.For example, dipole
Aspherical formula (even order aspherical formula), strange level aspherical formula (odd order aspherical
), and Q types richness compares expression formula formula（Q-type Forbes）Deng.Certainly, it will be readily apparent to those skilled in the art that also existing
For representing many kinds of expression formulas of the aspheric region feature of optical surface.Additionally, the selection of aspheric surface expression formula is for artificial crystalline substance
The design of body is not crucial, it is critical only that the design object of spherical aberration value, as it was previously stated, the application based on extended depth of field and
Improve the consideration of eyeglass omnibearing imaging quality and set -0.1-0 μm of weak spherical aberration.In addition as those skilled in the art institute is bright
In vain, spherical aberration value with select effective optical aperture size and incide the light convergence of artificial intraocular lensess to have direct relation.Such as front institute
State, -0.1-0 μm of the weak negative spherical aberration that the application is limited is that artificial intraocular lensess are effective at 5 millimeters in the convergence light that Jing corneas reflects
The spherical aberration presented after incident artificial intraocular lensess under optical aperture.The application by provide be so designed that with weak aspheric people
Work crystal, it is possible to obtain more preferable depth of focus, makes aspheric intraocular lens place to eyeglass eccentric and incline the higher tolerance of presence
Tolerance, so as to weaken aspheric intraocular lens because placing the increase of higher order aberratons that are eccentric and/or causing when inclining.
As it was previously stated, the aspherical shape of the optical surface of artificial intraocular lensess can be described by various expression formulas.Here, originally
Application characterizes the optical surface of artificial intraocular lensess with following formula：
Wherein：It is some the song on circular arc summit with interplanar vertical dimension, C when radius is r that S (r) is represented on curved surface
Rate, k are the constants of the cone, and A1, A2, A3... are even asphericity coefficients.
In order to optimize artificial intraocular lensess（IOL）Surface configuration obtaining foregoing weak negative spherical aberration design object, this Shen
Please be preferably used form factor, the curvature of centre of optical surface, the center thickness of optical surface, edge thickness, incident ray
The parameters such as degree of focus, effective optical aperture, paraxial smooth focus point, distal shaft light focus point, the light refractive index of material and dispersive power
It is optimized.Certainly, it will be readily apparent to those skilled in the art that other specification can also be present.Preferably, it is being optimized to obtain
During obtaining the application design object, selected parameter such as edge thickness, focus incident light degree, effective optical aperture
Footpath, paraxial smooth focus point, distal shaft light focus point, the light refractive index of material and dispersive power are held essentially constant.
As it was previously stated, total diopter of artificial intraocular lensessIt is the diopter of front optical surface 3 and rear optical surface 41 He2
Summation.It is obvious, for same total diopter, can have different number of1 He2 combination.In order to carry out to various combinations
Difference, is represented using parameter X of form factor is referred to as1 HeRelative distribution between 2, which is defined as：X=（R1+
R2）/（R2-R1）, wherein, R1 and R2 is the radius of curvature of front optical surface and rear optical surface respectively.According to Weir Buddhist moral
Weford equations（Referring to G.Smith, C-W.Lu, " The Spherical Aberration of Intraocular
Lens ", Opthal. Physiol. Opt 8:287-294,1988）Understand, the spherical aberration of lens and the form factor phase of lens
Close.Referring to Figure 12, it is schematically shown that the primary positive spherical aberrations of IOL of certain material and the relation of form factor.Can be with from Figure 12
Find out, intrinsic positive spherical aberration（I.e. primary positive spherical aberration）Can be controlled relatively small, such as when form factor is selected in 0.21-
When between 2.1, intrinsic positive spherical aberration is less than 0.01 micron.But, the form factor more than 1 is generally not used for artificial intraocular lensess, because
That is substantially meniscuss.Preferably, the application is limited to form factor between 0.1-0.75, it is highly preferred that in 0.16-
Between 0.38.The one side that selects of the numerical value of form factor can improve the precision of target negative spherical aberration design in actual production
（Primary positive spherical aberration is reduced to into less than 0.01 micron for example）, putting after on the other hand can also reducing being implanted into due to artificial intraocular lensess
The too fast phenomenon of aspheric surface crystal image quality decrease caused by the error of position.
Referring to Figure 13, the first example of the form factor distribution according to the application design is shown.Can from Figure 13
Go out, form factor of the crystal that the application is designed when diopter is 10D-30D is between 0.16-0.38.
Referring to Figure 14, the second example of the form factor distribution according to the application design is shown.Can from Figure 14
Go out, form factor of the crystal that the application is designed when diopter is 6.0D-34.0D is between 0.1-0.29.
Referring to Figure 15, the 3rd example of the form factor distribution according to the application design is shown.Can from Figure 15
Go out, form factor of the crystal that the application is designed when diopter is 6.0D-34.0D is between 0.20-0.36.
Referring to Figure 16, the 4th example of the form factor distribution according to the application design is shown.Can from Figure 16
Go out, form factor of the crystal that the application is designed when diopter is 6.0D-34.0D is between 0.30-0.45.
Referring to table three, show that according to the negative spherical aberration of the application a kind of Exemplary artificial's crystal when being -0.05 micron sets
Meter（Corresponding to the first example of form factor distribution）, between -91.774 to -9.583, A1=A2=0's wherein parameter k, A3 exist
5.867E-05 between 8.059E-05.
Table three
Referring to table four, another kind of Exemplary artificial's crystal when being -0.05 micron is shown according to the negative spherical aberration of the application
Design（Corresponding to the 3rd example of form factor distribution）, wherein parameter k=0, A1=0, A2 is in 1.225E-04 to 4.547E-04
Between, A3 is between -5.062E-06 to -1.083E-06.
Table four
Referring to table five, show that according to the negative spherical aberration of the application another kind of Exemplary artificial's crystal when being -0.1 micron sets
Meter（Corresponding to the 4th example of form factor distribution）, between -115.376 to -10.666, A1=0's wherein parameter k, A2 exist
Between 1.865E-04 to 2.220E-04, A3 is between -8.928E-07 to -1.793E-06.
Referring to table six, another Exemplary artificial's crystal design when being 0 is shown according to the negative spherical aberration of the application（Correspondence
In the second example of form factor distribution）, wherein parameter k between -86.841 to -7.413, A1=A2=A3=0.
Table six
One skilled in the art will readily appreciate that the aspheric surface of designed artificial intraocular lensess can be arranged on front optical surface,
Rear optical surface can be arranged on, aspheric surface etc. can be with front optical surface and rear optical surface.
As it was previously stated, the application is limited to form factor between 0.1-0.75, it is highly preferred that being limited to 0.16-
Between 0.38.The application is limited to form factor in such narrow range region and is objectively also acting to artificial intraocular lensess
Optics secondary principal plane（Optics principal plane after i.e.）Excursion control.Optics secondary principal plane is considered as eyeglass light
" center of gravity " of focal power, represents the active position of crystal.For the aspheric faceted crystal of weak negative spherical aberration, the meter of crystal focal power is controlled
It is precisely to realize the guarantee of negative spherical aberration design to calculate error.For the artificial intraocular lensess with different optical powers, if effectively optics
Position relative constancy, then the error that crystal focal power is calculated will be relatively reduced.Generally, effective optical position of crystal is not true
There is about 1.72 times of linear relationship in the qualitative calculation error with focal power.That is, 0.1 millimeter of effective light degree
The error put causes the calculation error of the focal power of crystal 0.172D.As shown in figure 17, crystal form factor in 0.16-
The change of corresponding optics secondary principal plane position when between 0.38.As can be seen from Figure 17, optics secondary principal plane position from-
0.028mm is changed between 0.026mm, i.e. excursion in 0.054mm, therefore correspondingly, by effective optical position
The calculation error of the focal power caused by uncertainty is controlled in 0.09D.It can thus be seen that the application is for optics
The stability contorting of two principal planes can realize that artificial intraocular lensess are injected into the calculating accuracy of rear focal power.
Although at least one one exemplary embodiment is described in detailed description above, it should be appreciated that existing a large amount of
Deformation.It is to be further appreciated that an one exemplary embodiment described here or multiple one exemplary embodiments are only example, not
It is intended to limit scope of the present application, the suitability or construction by any way.Conversely, detailed description above will be art technology
The guide of personnel's provides convenient is implementing an one exemplary embodiment or multiple one exemplary embodiments.It should be understood that without departing from by
The function of element and arrangement can be done in the case of the application scope that claims and its legal equivalent are illustrated
Go out various change.
Claims (19)
1. a kind of artificial intraocular lensess, the artificial intraocular lensess include：
Opticator with optical surface；
The several buttons loop being connected with the opticator；
Characterized in that, the optical surface of the opticator be aspheric surface, wherein Jing corneas refraction convergence light 5 milli
Under meter You Xiao optical apertures after the incident artificial intraocular lensess, the spherical aberration that the artificial intraocular lensess are presented is -0.1-0 μm.
2. artificial intraocular lensess as claimed in claim 1, it is characterised in that the artificial intraocular lensess have the thang-kng more than 6.0 millimeters
Aperture.
3. artificial intraocular lensess as claimed in claim 2, it is characterised in that the artificial intraocular lensess are with 6.5 millimeters of clear aperature.
4. artificial intraocular lensess as claimed in claim 1, it is characterised in that the artificial intraocular lensess provide bending from 6.0D to 34.0D
Luminosity.
5. artificial intraocular lensess as claimed in claim 1, it is characterised in that the artificial intraocular lensess use crosslinked polyolefin materials system
Into.
6. artificial intraocular lensess as claimed in claim 5, it is characterised in that the artificial intraocular lensess are more than 1.51 using light refractive index
Make with crosslinked polyolefin materials of the Abbe number more than 49.5.
7. artificial intraocular lensess as claimed in claim 6, it is characterised in that the artificial intraocular lensess are 1.515 using light refractive index
It is made up of 50 crosslinked polyolefin materials with Abbe number.
8. artificial intraocular lensess as any one of claim 1-7, it is characterised in that the optical surface includes front optics table
Face and rear optical surface, wherein front optical surface and/or rear optical surface are aspheric surface.
9. artificial intraocular lensess as any one of claim 1-7, it is characterised in that the optical surface includes front optics table
Face and rear optical surface, wherein front optical surface and rear optical surface are combined as aspheric surface with certain proportion.
10. artificial intraocular lensess as any one of claim 1-7, it is characterised in that the spherical aberration is by the optics
The optical modeling on surface is optimized realization, wherein the optical modeling includes the middle innermost being of the selected shape factor, optical surface
Rate, the center thickness of optical surface, edge thickness, focus incident light degree, effective optical aperture, paraxial smooth focus point, distal shaft
Light focus point, the light refractive index of material and dispersive power.
11. artificial intraocular lensess as claimed in claim 10, it is characterised in that edge thickness, incident illumination described in optimization process
Line focus degree, effective optical aperture, paraxial smooth focus point, distal shaft light focus point, the light refractive index of material and dispersive power are protected
Hold constant.
12. artificial intraocular lensess as claimed in claim 10, it is characterised in that the form factor is between 0.1-0.75.
13. artificial intraocular lensess as claimed in claim 12, it is characterised in that the form factor is between 0.16-0.38.
14. artificial intraocular lensess as claimed in claim 10, it is characterised in that the expression formula of the optical modeling of the optical surface
For：S(r) =
Wherein：C is the curvature of the optical surface；K is the constant of the cone；A1, A2, A3... are order aspherical coefficients.
15. artificial intraocular lensess as claimed in claim 14, it is characterised in that the spherical aberration is -0.05 μm, and wherein k is -91.774
To between -9.583, A1=A2=0, A3 is between 5.867E-05 to 8.059E-05.
16. artificial intraocular lensess as claimed in claim 14, it is characterised in that the spherical aberration is -0.05 μm, wherein k=0, A1=0,
, between 1.225E-04 to 4.547E-04, A3 is between -5.062E-06 to -1.083E-06 for A2.
17. artificial intraocular lensess as claimed in claim 14, it is characterised in that the spherical aberration is -0.1 μm, and wherein k is -115.376
To between-10.666, A1=0, A2 between 1.865E-04 to 2.220E-04, A3-8.928E-07 to-1.793E-06 it
Between.
18. artificial intraocular lensess as claimed in claim 14, it is characterised in that the spherical aberration be 0 μm, wherein k -86.841 to -
7.413 between, A1=A2=A3=0.
19. artificial intraocular lensess as any one of claim 1-7,15-18, it is characterised in that the light of the artificial intraocular lensess
The excursion of position of secondary principal plane is learned in 0.054 millimeter.
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| CN201620522067.6U CN206102780U (en) | 2016-06-01 | 2016-06-01 | Aspherical intraocular lens |
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| CN201620522067.6U CN206102780U (en) | 2016-06-01 | 2016-06-01 | Aspherical intraocular lens |
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| WO2017206789A1 (en) * | 2016-06-01 | 2017-12-07 | 西安浦勒生物科技有限公司 | Innovative biocompatible hydrophobic material-based new posterior chamber artificial lens |
| CN107468377A (en) * | 2017-07-25 | 2017-12-15 | 南开大学 | A kind of big depth of focus aspheric intraocular lens for being used to correct presbyopia |
| CN109363802A (en) * | 2018-11-02 | 2019-02-22 | 无锡蕾明视康科技有限公司 | A kind of progressive modulation type aspheric intraocular lens of axial spherical aberration |
| CN110613532A (en) * | 2019-10-24 | 2019-12-27 | 西安浦勒生物科技有限公司 | Posterior chamber type lens designed by toric surface |
| CN112494175A (en) * | 2020-11-25 | 2021-03-16 | 杭州爱晶伦科技有限公司 | Posterior chamber type aspheric intraocular lens with lens |
| CN113491597A (en) * | 2020-03-19 | 2021-10-12 | 河南赛美视生物科技有限公司 | Aspheric extended focal depth intraocular lens |
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| WO2017206789A1 (en) * | 2016-06-01 | 2017-12-07 | 西安浦勒生物科技有限公司 | Innovative biocompatible hydrophobic material-based new posterior chamber artificial lens |
| CN107440818A (en) * | 2016-06-01 | 2017-12-08 | 西安浦勒生物科技有限公司 | A kind of new back room artificial lens based on innovation biocompatibility hydrophobic material |
| CN107468377A (en) * | 2017-07-25 | 2017-12-15 | 南开大学 | A kind of big depth of focus aspheric intraocular lens for being used to correct presbyopia |
| CN107468377B (en) * | 2017-07-25 | 2019-06-04 | 南开大学 | It is a kind of for correcting the big depth of focus aspheric intraocular lens of presbyopia |
| CN109363802A (en) * | 2018-11-02 | 2019-02-22 | 无锡蕾明视康科技有限公司 | A kind of progressive modulation type aspheric intraocular lens of axial spherical aberration |
| CN110613532A (en) * | 2019-10-24 | 2019-12-27 | 西安浦勒生物科技有限公司 | Posterior chamber type lens designed by toric surface |
| CN110613532B (en) * | 2019-10-24 | 2022-02-22 | 西安眼得乐医疗科技有限公司 | Posterior chamber type lens designed by toric surface |
| CN113491597A (en) * | 2020-03-19 | 2021-10-12 | 河南赛美视生物科技有限公司 | Aspheric extended focal depth intraocular lens |
| CN112494175A (en) * | 2020-11-25 | 2021-03-16 | 杭州爱晶伦科技有限公司 | Posterior chamber type aspheric intraocular lens with lens |
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