CN109363802A - A kind of progressive modulation type aspheric intraocular lens of axial spherical aberration - Google Patents
A kind of progressive modulation type aspheric intraocular lens of axial spherical aberration Download PDFInfo
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- CN109363802A CN109363802A CN201811301451.3A CN201811301451A CN109363802A CN 109363802 A CN109363802 A CN 109363802A CN 201811301451 A CN201811301451 A CN 201811301451A CN 109363802 A CN109363802 A CN 109363802A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
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Abstract
The invention discloses a kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, the intraocular lens include optical bodies (1), the first support button loop (2) and the second support button loop (3), and the optical bodies (1) have the aspherical of non-constant characterization equation.Optical bodies of the present invention are the optics area with the progressive modulation of axial spherical aberration, can be retained under different pupil sizes certain positive spherical aberration (depth of focus), and visual quality is promoted；Higher order aberratons can be taken into account simultaneously, have better adapted to slight intraocular lens' deviation, focal power and image quality is reduced to the susceptibility of implantation position, reduces operative reduction.
Description
Technical field
The present invention relates to intraocular lens' technical fields, more particularly, to a kind of axis by non-constant characterization equation design
To the progressive modulation type aspheric intraocular lens of spherical aberration.
Background technique
Natural lens in human eye are colorless and transparent and very soft crystalline lenses in the baby being just born, with the age
Increase, under the influence of the change of external condition, such as the radiation element of ultraviolet light, which will become increasingly
It is hard and become coloured crystalline lens, when people it is living to 50 to threescore more than when, have 30 or so percent natural lens
Brown color and muddiness will be will become, and be hardened, the function of adjustable focus is not only lost, or even completely invisible, when this
When happening, this natural lens (i.e. cataractous lens) will have to go to replace with an artificial crystalline lens, make
Its restore cataract patient eye eyesight.
One typical intraocular lens is since optical crystal and the arm of support are constituted, and wherein lens optics focus
Make it to see object on light to optic nerve and the effect of arm is to support its optics area, be allowed to optics area be located at it is intraocular
Center can effectively focus.The implantation of artificial lens of early stage, First Essential is to aid in cataract patient and recovers lost eyesight, with ball
Based on the intraocular lens of face.With the continuous development of science and technology in mankind's daily life to the continuous promotion of visual needs,
Requirement of the patient to implantation of artificial lens is not only in that " visible ", also " to be seen clearly "." seeing clearly ", can in optics
To be interpreted as the high resolution of optical system, image quality is good, the smaller (wave of actual wavefront and ideal zero deflection state of wave front aberration
Before between deviation it is smaller).Usual researcher with Zernike multinomial come quantitative description opthalmic optics' wave front aberration, wherein ball
Difference is to influence the implantation most important factor of eye image quality.
When spherical lens rim ray passes through positive spherical lens, the degree being refracted is more much harder than central ray, i.e.,
Edge focal power is big, and center focal power is small, whole that positive spherical aberration is presented and is difficult to control.It is aspherical more to optical design band
Freedom degree (including radius of curvature, circular cone coefficient and high-order term etc.), by changing the shape of rims of the lens, in rearrangement
Heart district domain and fringe region allow lens that negative spherical aberration distribution is presented the convergence ability of light.It is understood that eye cornea
It is with positive spherical aberration, and the aspheric intraocular lens of negative spherical aberration balance the intrinsic positive spherical aberration of human eye, can obtain so most
Good imaging point.Spherical surface intraocular lens then cannot achieve.
Due to the having differences property of distribution of eye cornea spherical aberration, meet normal distribution law, most eye cornea balls
Difference is+0.27 μm or so (in 6mm pupil size, measurement is obtained).Researcher starts to design the aspheric of different spherical aberrations
Face intraocular lens' spherical aberration value substantially between -0.27um~0um, as patent US4504982, US5050981,
AU2007247491, EP2189134, CA2590166 etc..The intraocular lens of all these negative spherical aberration distributions, can only guarantee
6mm pupil position achieve the purpose that it is expected retain certain positive spherical aberration, the remaining positive spherical aberration of medium and small pupil position, reservation cannot
It meets the requirements.
Summary of the invention
In view of the above-mentioned problems existing in the prior art, the applicant provides a kind of progressive modulation type of axial spherical aberration is non-
The design of spherical surface intraocular lens.Optical bodies of the present invention have the aspherical of non-constant characterization equation.The design is in different pupils
It can retain under pore size certain positive spherical aberration (depth of focus), promote visual quality；Higher order aberratons can be taken into account simultaneously, it is preferably suitable
Slight intraocular lens' deviation has been answered, focal power and image quality has been reduced for the susceptibility of implantation position, reduces operative reduction.
Technical scheme is as follows:
A kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, including optical bodies (1), the first support button loop (2)
With the second support button loop (3), the optical bodies (1), the first support button loop (2) and the second support button loop (3) are an integral structure, use
Same material, integrally formed, the optical bodies (1) are made of two optical surfaces, and an optical surface is spherical surface, another
Face be have it is non-constant characterization equation it is aspherical；
The aspherical determination method: it using the vertex of optical surface as origin O, using optical axis as coordinate Z axis, establishes any
Rectangular coordinate system in space, the abscissa X-axis and coordinate Y-axis of the coordinate system and the optical surface are tangent, described aspherical
The drop shadow curve on above-mentioned Y-Z plane have non-constant characterization equation, it is specific as follows:
Wherein, zn(yn) it is aspherical drop shadow curve's expression formula on two-dimensional coordinate system plane Y-Z, c is described non-
The inverse of the basic sphere curvature radius of spherical surface, ynFor vertical range of any point apart from coordinate Z axis, A on the curveiFor
Aspherical high-order coefficient, QnFor aspherical quadratic surface constant；
Curve a, curve b, curve c ... curve n indicate the family of curves of known different spherical aberrations distribution, spherical aberration distribution to
0um~-0.2um, the corresponding determining Q value of each of them curve and different, respectively Qa、Qb、Qc…Qn, it is
Column Q value can be attributed to the function about y from spherical aberration envelope:
α, β, χ, δ are constant, QnRestriction limited by spherical aberration envelope, by arbitrary four known point (ya,Qa)、(yb,
Qb)、(yc,Qc)、(yd,Qd) bring solve system of equation into, α, β, χ, δ are obtained, equation group is as follows:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is i.e. corresponding different
Pupil diameter 2ya、2yb、2yc…2yn, n is the integer from 1 to positive infinity.
It, can be in the hope of array (y according to the above aspherical equation racea, za)、(yb, zb)、(yc, zc)、…(yn, zn)
To obtain entire non-constant aspherical all data points in three-dimensional space.
The diameter in effective optics area of the optical bodies (1) is 5.5~6.5mm, 0.65~1.25mm's of center thickness
Biconvex/lens of concavo convex lens；First support is fastened with a rope, string, etc. (2), the thickness of the second support button loop (3) is 0.15~0.35mm.
The first support button loop (2), second support button loop (3) surface are equipped with oblique sawtooth grooves or raised frosted；The mill
The roughness of sand or the height of oblique sawtooth are greater than 40 μm.
The first support button loop (2), second support the surface of button loop (3) to be equipped with oblique sawtooth grooves or raised frosted, and tiltedly saw
The angle α of plane belonging to mark of mouth slot or the width of raised frosted be 0.2~1.0mm, the beveled edge of oblique sawtooth and support are fastened with a rope, string, etc. is -20
Between~20 °.
The hydrophobic polypropylene acid that the optical bodies (1) by refractive index are 1.48~1.55, abbe number is 40~55
Ester is made.
The optical bodies (1), the first support button loop (2), second support button loop (3) three's collective effect can be only achieved artificial crystalline substance
The effect stable in implantation eye position of shape body, preferably plays the effect of the progressive modulation of axial spherical aberration.
The present invention also provides a kind of preparation methods of the progressive modulation type aspheric intraocular lens of axial spherical aberration, including such as
Lower step:
(1) optical design: firstly, determining that axial progressive spherical aberration is distributed envelope.According to eye cornea spherical aberration distribution curve
And the reserved residual spherical aberration value under different pupil diameters, the spherical aberration distribution for fitting the progressive modulation of axial spherical aberration are bent
Line.As shown in figure 4, in 0~3mm pupil diameter, residual spherical aberration 0um；In 3.5mm pupil diameter, residual spherical aberration is+
0.02um；Under under 4mm pupil diameter, residual spherical aberration be+0.035um；Under 4.5mm pupil diameter, residual spherical aberration be+
0.07um, under 5mm, 5.5mm, 6mm pupil diameter, residual spherical aberration is+0.07um.This ensure that different pupil diameters
Under, the adaptive eye cornea spherical aberration distribution of optical bodies (1), implantation eye retains a certain amount of remaining positive spherical aberration.Secondly, will gradually
Difference of scoring modulates aspherical spherical aberration and is distributed the curvilinear equation and coordinate points be converted in three-dimensional space.As shown in figure 5, fitting obtains
The spherical aberration distribution curve of the progressive modulation of axial spherical aberration marked in the form of envelope (in geometry, the envelope of some family of curves
Line (Envelope) is that have with every line of the family of curves to an a little less tangent curve).Curve a, curve b, curve
C ... curve n indicates the family of curves of different spherical aberrations distribution, and spherical aberration distribution is to 0um~-0.2um.Each of them curve corresponding one
The Q value of a determination and different, respectively Qa、Qb、Qc…Qn, serial Q value can be attributed to from spherical aberration envelope about y
Function:
α, β, χ, δ are constant, QnRestriction limited by spherical aberration envelope, by arbitrary four known point (ya,Qa)、(yb,
Qb)、(yc,Qc)、(yd,Qd), bring solve system of equation into, obtain α, β, χ, δ, equation group is as follows:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is i.e. corresponding different
Pupil diameter 2ya、2yb、2yc…2yn.N is the integer from 1 to positive infinity, aspherical within the scope of pupil diameter 0mm~6mm
Drop shadow curve is infinitely made fine, and does not have constant characterization equation macroscopically.In pupil diameter 2ynLocate non-curved part characterization
Equation are as follows:
It, can be in the hope of the coordinate points (y in drop shadow curve aspherical on y-z plane according to the above aspherical equation racea, za)、
(yb, zb)、(yc, zc)、…(yn, zn), drop shadow curve is symmetrically obtained aspherical point of the progressive modulation of entire axial spherical aberration
Cloth.Finally, constructing initial model in Zemax, then optimization obtains optimal desired effect.
(2) it turn-milling cutting: Vehicle Processing substrate refractor: according to the machined parameters of the front and back optical surface of optical design, compiles
Write lathe program；Using diamond single-point cutting technology, Vehicle Processing goes out optical bodies (1)；Milling machine program is write, optics is milled out
The shape in area and have frosted/jagged button loop foot.
(3) polishing treatment: the method polished using low temperature roller.
(4) test verifying: in simulation eye system, MTF image quality is tested under different light bars, and is analyzed 0.5mm pairs eccentric
The influence of image quality.
The present invention is beneficial to be had the technical effect that
The optics area of optical bodies (1) of the present invention is aspherical to have non-constant characterization equation, and optical bodies (1) are in implantation eye
Middle imaging, as (mainly 3mm is transitioned into 6mm, it is considered that human eye spherical aberration is in 3mm pupil diameter for the variation of pupil size
Zero, therefore do not consider), it is different from traditional design, more than 3mm pupil, retains certain positive spherical aberration always.
Spherical aberration has not only axially been modulated in the optics area of optical bodies (1) of the present invention, but also is taken into account and eliminated part high-order picture
Difference, such as clover aberration, longitudinal coma, horizontal coma.
The optics area of optical bodies (1) of the present invention is imaged in implantation eye, remains under 3mm~6mm pupil diameter
Certain depth of focus, visual quality are preferable.
Optical bodies (1) of the present invention are imaged in implantation eye, and focal power and image quality are lower to the susceptibility of implantation position, more
Slight intraocular lens' deviation has been adapted to well,
After being implanted into human eye, postoperative is reduced the present invention, has widened complicated cataract operation intraocular lens indication.
The present invention is suitable for wide in range corneal asphericity Q compared to conventional aspheric design.
Detailed description of the invention
Fig. 1 is 1 structural schematic diagram of the embodiment of the present invention；
Fig. 2 is 2 structural schematic diagram of the embodiment of the present invention；
Fig. 3 is 3 structural schematic diagram of the embodiment of the present invention；
Fig. 4 is the progressive modulation type aspheric design schematic diagram of 1 axial spherical aberration of the embodiment of the present invention；
Fig. 5 is the aspherical spherical aberration distribution curve of the progressive modulation type of 1 axial spherical aberration of the embodiment of the present invention；
Fig. 6 is 1 focal power of the embodiment of the present invention with pupil distribution curve；
Fig. 7 is optical-modulation transfer function (MTF) curve at 3mm light bar & bias 0.5mm of the embodiment of the present invention 1；
Fig. 8 is optical-modulation transfer function (MTF) curve at 5mm light bar & bias 0.5mm of the embodiment of the present invention 1；
Fig. 9 is contrast sensitivity (CSF) curve at 5mm light bar & bias 0.5mm of the embodiment of the present invention 1；
Figure 10 is the spherical aberration distribution curve comparison diagram of the embodiment of the present invention 1, embodiment 2, embodiment 3.
Specific embodiment
With reference to the accompanying drawings and examples, the present invention is specifically described.
Embodiment 1
As shown in Figure 1, a kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, the intraocular lens include light
Main body (1), the first support button loop (2) and the second support button loop (3) are learned, the optical bodies 1 have the aspheric of non-constant characterization equation
Face, in pupil diameter 2ynLocate aspherical part characterization equation are as follows:
In pupil diameter 2ya=3mm, 2yb=3.5mm, 2yc=4mm, 2ynAt=6mm, aspherical Qa、Qb、Qc、QnRespectively
It is -3.3, -6.2, -9.5, -13.5,
The optical bodies 1 are an integral structure with first the 2, second support of support button loop button loop 3, whole using same material
It is body formed；
First support button loop the 2, second support button loop, 3 surfaces are equipped with oblique sawtooth grooves；The height of oblique sawtooth is greater than 40 μm.
The diameter in effective optics area of the optical bodies 1 is 6.0mm, the bi-convex lens sheet of center thickness 0.67mm；Institute
The thickness for stating the 2, second support of the first support button loop button loop 3 is 0.15mm；
The optical bodies 1 are made of refractive index of 1.544, abbe number of 42 hydrophobic polyacrylate.
The surface of the 2, second support of first support button loop button loop 3 is equipped with several oblique sawtooth grooves, and tiltedly sawtooth grooves width
Included angle α for plane belonging to 0.2mm, the beveled edge of oblique sawtooth and the support button loop is 20 °.
The mentality of designing of the intraocular lens and the preparation method comprises the following steps:
(1) design scheme: the progressive modulation type aspheric intraocular lens of axial spherical aberration become in pupil diameter in 2mm~6mm
Change in range, implantation eye residual spherical aberration maintains+0.07um；
(2) optical design: firstly, determining that axial progressive spherical aberration is distributed envelope.According to eye cornea spherical aberration distribution curve
And the reserved residual spherical aberration value under different pupil diameters, the spherical aberration distribution for fitting the progressive modulation of axial spherical aberration are bent
Line.As shown in figure 4, in 0~3mm pupil diameter, residual spherical aberration 0um；In 3.5mm pupil diameter, residual spherical aberration is+
0.02um；Under 4mm pupil diameter, residual spherical aberration is+0.035um；Under 4.5mm pupil diameter, residual spherical aberration be+
0.07um；Under 5mm, 5.5mm, 6mm pupil diameter, residual spherical aberration is+0.07um.This ensure that different pupil diameters
Under, the adaptive eye cornea spherical aberration distribution of optical bodies (1), implantation eye retains a certain amount of remaining positive spherical aberration.Secondly, will gradually
Difference of scoring modulates aspherical spherical aberration and is distributed the curvilinear equation and coordinate points be converted in three-dimensional space.As shown in figure 5, fitting obtains
The spherical aberration distribution curve of the progressive modulation of axial spherical aberration marked in the form of envelope (in geometry, the envelope of some family of curves
Line (Envelope) is that have with every line of the family of curves to an a little less tangent curve).Curve a, curve b, curve
C ... curve n indicates the family of curves of different spherical aberrations distribution, and spherical aberration distribution is to 0um~-0.2um.Each of them curve corresponding one
The Q value of a determination and different, respectively Qa、Qb、Qc…Qn, serial Q value can be attributed to from spherical aberration envelope about y
Equation:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is i.e. corresponding different
Pupil diameter 2ya、2yb、2yc…2yn.N is the integer from 1 to positive infinity, aspherical within the scope of pupil diameter 0mm~6mm
Drop shadow curve is infinitely made fine, and does not have constant characterization equation macroscopically.In pupil diameter 2ya、2yb、2yc…2ynLocate non-
Locally characterization equation is respectively as follows: curved surface
It, can be in the hope of the coordinate points (y in drop shadow curve aspherical on y-z plane according to the above aspherical equation racea, za)、
(yb, zb)、(yc, zc)、…(yn, zn), drop shadow curve is symmetrically obtained aspherical point of the progressive modulation of entire axial spherical aberration
Cloth.Finally, constructing initial model in Zemax, then optimization obtains optimal desired effect.
(3) Vehicle Processing substrate refractor: according to the parameter in the optics area of design, lathe program is write；Utilize diamond
Single-point cutting technology, Vehicle Processing go out disk intraocular lens；Milling machine program is write, mills out the shape in optics area and with mill
The button loop foot of sand shape.
(4) last polishing treatment obtains the intraocular lens of optical surface qualification.
(5) test is analyzed in phantom eye
Interpretation of result and discussion:
The constant spherical aberration design of axial progressive modulation type aspheric intraocular lens, effectively improves intraocular lens' light focus
Spend the tolerance to implantation position.From fig. 6 it can be seen that in pupil radium within the scope of 0~1.5mm of pupil radium, it is different
The variation for designing focal power is relatively slower, but axial progressive modulation type aspheric intraocular lens power curve is more flat
It is slow；Within the scope of 1.5~3mm of pupil radium, first gentle one section so for axial progressive modulation type aspheric intraocular lens focal power
Cataclysm afterwards, and SN60WF design and ZCB00 design power curve are whole precipitous obvious.It may be concluded that intraocular lens
Implantation is eccentric smaller on axial progressive modulation type aspheric intraocular lens focal power influence, in identical eccentric situation, axis
Variation to progressive modulation type aspheric intraocular lens focal power is minimum, this facilitates patient and reach most preferably to correct defects of vision.
The progressive design of axial spherical aberration of axial progressive modulation type aspheric intraocular lens, effectively improves intraocular lens
Tolerance of the retina image-forming quality to implantation position.Such as Fig. 7, under 3mm light bar & bias 0.5mm state, axial progressive modulation
Modulation transfer function (MTF) curve of type aspheric intraocular lens is significantly better than SN60WF design and ZCB00 design.Simultaneously
In such as Fig. 8, the modulation transfer function of axial progressive modulation type aspheric intraocular lens under 5mm light bar bias 0.5mm state
(MTF) curve is better than SN60WF design and ZCB00 design；(such as Fig. 9) axial progressive tune in contrast sensitivity function (CSF) curve
The estimated implantation eye vision of type aspheric intraocular lens processed is 0.98, also superior to 0.85 He of estimated eyesight of SN60WF design
The estimated eyesight 0.76 of ZCB00 design.
Therefore axial progressive modulation type aspheric intraocular lens overcome the deficiency of Alcon company and the design of AMO company,
In big pupil (3~6mm) range, retain constant positive spherical aberration.Implantation eye visual quality is effectively promoted in the design, reduces
The susceptibility of focal power and image quality for implantation position.
Embodiment 2
As shown in Fig. 2, a kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, the intraocular lens include light
Main body (1), the first support button loop (2) and the second support button loop (3) are learned, the optical bodies 1 have the aspheric of non-constant characterization equation
Face, in pupil diameter 2ynLocate non-curved part characterization equation are as follows:
In pupil diameter 2ya=3mm, 2yb=3.5mm, 2yc=4mm, 2ynAt=6mm, aspherical Qa、Qb、Qc、QnRespectively
It is -10.6, -20.2, -28.4, -39.7
The optical bodies 1 are an integral structure with first the 2, second support of support button loop button loop 3, whole using same material
It is body formed；
First support button loop the 2, second support button loop, 3 surfaces are equipped with oblique sawtooth grooves；The height of oblique sawtooth is greater than 40 μm.
The diameter in effective optics area of the optical bodies 1 is 6.0mm, the bi-convex lens sheet of center thickness 0.67mm；Institute
The thickness for stating the 2, second support of the first support button loop button loop 3 is 0.15mm；
The optical bodies 1 are made of refractive index of 1.544, abbe number of 45 hydrophobic polyacrylate.
The surface of the 2, second support of first support button loop button loop 3 is equipped with several oblique sawtooth grooves, and tiltedly sawtooth grooves width
Included angle α for plane belonging to 0.2mm, the beveled edge of oblique sawtooth and the support button loop is 20 °.
The process for manufacturing intraocular lenses are as follows:
(1) design scheme: the progressive modulation type aspheric intraocular lens of axial spherical aberration become in pupil diameter in 2mm~6mm
Change in range, implantation eye residual spherical aberration maintains+0.1um；
(2) optical design: firstly, determining that axial progressive spherical aberration is distributed envelope.According to eye cornea spherical aberration distribution curve
And the reserved residual spherical aberration value under different pupil diameters, the spherical aberration distribution for fitting the progressive modulation of axial spherical aberration are bent
Line.As shown in Figure 10, in 0~3mm pupil diameter, residual spherical aberration 0um；In 3.5mm pupil diameter, residual spherical aberration is+
0.025um；Under 4mm pupil diameter, residual spherical aberration is+0.04um；Under 4.5mm pupil diameter, residual spherical aberration be+0.1um,
Under 5mm, 5.5mm, 6mm pupil diameter, residual spherical aberration is+0.1um.This ensure that under different pupil diameters, optics master
The adaptive eye cornea spherical aberration distribution of body (1), implantation eye retain a certain amount of remaining positive spherical aberration.Secondly, by progressive spherical aberration tune
It makes aspherical spherical aberration and is distributed the curvilinear equation and coordinate points be converted in three-dimensional space.As shown in figure 5, the axial ball that fitting obtains
The spherical aberration distribution curve of the progressive modulation of difference is marked in the form of envelope (in geometry, the envelope of some family of curves
It (Envelope), is to have with every line of the family of curves to an a little less tangent curve).Curve a, curve b, curve
C ... curve n indicates the family of curves of different spherical aberrations distribution, and spherical aberration distribution is to 0um~-0.2um.Each of them curve corresponding one
The Q value of a determination and different, respectively Qa、Qb、Qc…Qn, serial Q value can be attributed to from spherical aberration envelope about y
Equation:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is i.e. corresponding different
Pupil diameter 2ya、2yb、2yc…2yn.N is the integer from 1 to positive infinity, aspherical within the scope of pupil diameter 0mm~6mm
Drop shadow curve is infinitely made fine, and does not have constant characterization equation macroscopically.In the straight 2y of pupilnLocate non-curved part characterization side
Journey are as follows:
It, can be in the hope of the coordinate points (y in drop shadow curve aspherical on y-z plane according to the above aspherical equation racea, za)、
(yb, zb)、(yc, zc)、…(yn, zn), drop shadow curve is symmetrically obtained aspherical point of the progressive modulation of entire axial spherical aberration
Cloth.Finally, constructing initial model in Zemax, then optimization obtains optimal desired effect.
(3) Vehicle Processing substrate refractor: according to the parameter in the optics area of design, lathe program is write；Utilize diamond
Single-point cutting technology, Vehicle Processing go out disk intraocular lens；Milling machine program is write, mills out the shape in optics area and with mill
The button loop foot of sand shape.
(4) last polishing treatment obtains the intraocular lens of optical surface qualification.
(5) test is analyzed in phantom eye
Embodiment 3
As shown in figure 3, a kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, the intraocular lens include light
Main body (1), the first support button loop (2) and the second support button loop (3) are learned, the optical bodies 1 have the aspheric of non-constant characterization equation
Face, in pupil diameter 2ynLocate non-curved part characterization equation are as follows:
In pupil diameter 2ya=3.5mm, 2yb=4mm, 2yc=4.5mm, 2ynAspherical Q at=6mma、Qb、Qc、QnRespectively
It is -12.3, -21.3, -33.4, -52.5.
The optical bodies 1 are an integral structure with first the 2, second support of support button loop button loop 3, whole using same material
It is body formed；
First support button loop the 2, second support button loop, 3 surfaces are equipped with oblique sawtooth grooves；The height of oblique sawtooth is greater than 40 μm.
The diameter in effective optics area of the optical bodies 1 is 6.0mm, the bi-convex lens sheet of center thickness 0.67mm；Institute
The thickness for stating the 2, second support of the first support button loop button loop 3 is 0.15mm；
The optical bodies 1 are made of refractive index of 1.544, abbe number of 45~55 hydrophobic polyacrylate.
The surface of the 2, second support of first support button loop button loop 3 is equipped with several oblique sawtooth grooves, and tiltedly sawtooth grooves width
Included angle α for plane belonging to 0.2mm, the beveled edge of oblique sawtooth and the support button loop is 20 °.
The process for manufacturing intraocular lenses are as follows:
(1) design scheme: the progressive modulation type aspheric intraocular lens of axial spherical aberration become in pupil diameter in 3mm~6mm
Change in range, implantation eye residual spherical aberration maintains+0.05um；
(2) optical design: firstly, determining that axial progressive spherical aberration is distributed envelope.According to eye cornea spherical aberration distribution curve
And the reserved residual spherical aberration value under different pupil diameters, the spherical aberration distribution for fitting the progressive modulation of axial spherical aberration are bent
Line.As shown in Figure 10, in 0~3mm pupil diameter, residual spherical aberration 0um；In 3.5mm pupil diameter, residual spherical aberration is+
0.0125um；Under under 4mm pupil diameter, residual spherical aberration be+0.025um；Under 4.5mm pupil diameter, residual spherical aberration be+
0.05um, under 5mm, 5.5mm, 6mm pupil diameter, residual spherical aberration is+0.05um.This ensure that different pupil diameters
Under, the adaptive eye cornea spherical aberration distribution of optical bodies (1), implantation eye retains a certain amount of remaining positive spherical aberration.Secondly, will gradually
Difference of scoring modulates aspherical spherical aberration and is distributed the curvilinear equation and coordinate points be converted in three-dimensional space.As shown in figure 5, fitting obtains
The spherical aberration distribution curve of the progressive modulation of axial spherical aberration marked in the form of envelope (in geometry, the envelope of some family of curves
Line (Envelope) is that have with every line of the family of curves to an a little less tangent curve).Curve a, curve b, curve
C ... curve n indicates the family of curves of different spherical aberrations distribution, and spherical aberration distribution is to 0um~-0.2um.Each of them curve corresponding one
The Q value of a determination and different, respectively Qa、Qb、Qc…Qn, serial Q value can be attributed to from spherical aberration envelope about y
Equation:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is i.e. corresponding different
Pupil diameter 2ya、2yb、2yc…2yn.N is the integer from 1 to positive infinity, aspherical within the scope of pupil diameter 0mm~6mm
Drop shadow curve is infinitely made fine, and does not have constant characterization equation macroscopically.In the straight 2y of pupilnLocate non-curved part characterization side
Journey are as follows:
It, can be in the hope of the coordinate points (y in drop shadow curve aspherical on y-z plane according to the above aspherical equation racea, za)、
(yb, zb)、(yc, zc)、…(yn, zn), drop shadow curve is symmetrically obtained aspherical point of the progressive modulation of entire axial spherical aberration
Cloth.Finally, constructing initial model in Zemax, then optimization obtains optimal desired effect.
(3) Vehicle Processing substrate refractor: according to the parameter in the optics area of design, lathe program is write；Utilize diamond
Single-point cutting technology, Vehicle Processing go out disk intraocular lens；Milling machine program is write, mills out the shape in optics area and with mill
The button loop foot of sand shape.
(4) last polishing treatment obtains the intraocular lens of optical surface qualification.
(5) test is analyzed in phantom eye.
Claims (6)
1. a kind of progressive modulation type aspheric intraocular lens of axial spherical aberration, including optical bodies (1), the first support button loop (2) and
Second support button loop (3), the optical bodies (1), the first support button loop (2) and the second support button loop (3) are an integral structure, using same
A kind of material, it is integrally formed, which is characterized in that the optical bodies (1) are made of two optical surfaces, and an optical surface is
Spherical surface, another side be have it is non-constant characterization equation it is aspherical；
The aspherical determination method: it using the vertex of optical surface as origin O, using optical axis as coordinate Z axis, establishes arbitrary empty
Between rectangular coordinate system, the abscissa X-axis and coordinate Y-axis of the coordinate system and the optical surface are tangent, it is described it is aspherical
Drop shadow curve on above-mentioned Y-Z plane has non-constant characterization equation, specific as follows:
Wherein, zn(yn) it is aspherical drop shadow curve's expression formula on two-dimensional coordinate system plane Y-Z, c is described aspherical
Basic sphere curvature radius inverse, ynFor vertical range of any point apart from coordinate Z axis, A on the curveiFor aspheric
Face high-order coefficient, QnFor aspherical quadratic surface constant；
Curve a, curve b, curve c ... curve n indicate the family of curves of known different spherical aberrations distribution, spherical aberration distribution to 0um~-
0.2um, the corresponding determining Q value of each of them curve and different, respectively Qa、Qb、Qc…Qn, serial Q value can
To be attributed to the function about y from spherical aberration envelope:
α, β, χ, δ are constant, QnRestriction limited by spherical aberration envelope, by arbitrary four known point (ya,Qa)、(yb, Qb)、
(yc, Qc)、(yd, Qd) bring solve system of equation into, α, β, χ, δ are obtained, equation group is as follows:
Axial progressive spherical aberration envelope and family of curves meet at point A, B, C ... N respectively, and the abscissa of these points is corresponding different pupil
Bore dia 2ya、2yb、2yc…2yn, n is the integer from 1 to positive infinity.
It, can be in the hope of array (y according to the above aspherical equation racea, za)、(yb, zb)、(yc, zc)、…(yn, zn), it can
To entire non-constant aspherical all data points in three-dimensional space.
2. intraocular lens according to claim 1, which is characterized in that effective optics area of the optical bodies (1)
Diameter is 5.5~6.5mm, biconvex/lens of concavo convex lens of 0.65~1.25mm of center thickness；First support button loop (2), second
The thickness of support button loop (3) is 0.15~0.35mm.
3. intraocular lens according to claim 1, which is characterized in that the first support button loop (2), the second support button loop
(3) surface is equipped with oblique sawtooth grooves or raised frosted；The roughness of the frosted or the height of oblique sawtooth are greater than 40 μm.
4. intraocular lens according to claim 1, which is characterized in that the first support button loop (2), the second support button loop
(3) surface is equipped with oblique sawtooth grooves or raised frosted, and tiltedly sawtooth grooves or the width of raised frosted are 0.2~1.0mm, tiltedly
The angle α of plane belonging to the beveled edge and support button loop of sawtooth is between -20~20 °.
5. intraocular lens according to claim 1, which is characterized in that the optical bodies (1) are 1.48 by refractive index
~1.55, abbe number is made of 40~55 hydrophobic polyacrylate.
6. intraocular lens according to claim 1, which is characterized in that the optical bodies (1), first support button loop (2),
Second support button loop (3) three's collective effect can be only achieved intraocular lens' effect stable in implantation eye position, preferably play
The effect of the progressive modulation of axial spherical aberration.
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| CN112494175A (en) * | 2020-11-25 | 2021-03-16 | 杭州爱晶伦科技有限公司 | Posterior chamber type aspheric intraocular lens with lens |
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| CN113599021A (en) * | 2021-06-04 | 2021-11-05 | 天津世纪康泰生物医学工程有限公司 | Aspheric intraocular lens for resisting postoperative residual ametropia |
| CN113693779A (en) * | 2021-06-01 | 2021-11-26 | 天津世纪康泰生物医学工程有限公司 | Diffraction type multifocal intraocular lens with targeted light field distribution |
| CN117379225A (en) * | 2023-09-11 | 2024-01-12 | 无锡蕾明视康科技有限公司 | Toric astigmatic intraocular lens with reduced rotational sensitivity |
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