CN104127263B - Multifocal intraocular lenses - Google Patents

Multifocal intraocular lenses Download PDF

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CN104127263B
CN104127263B CN201310700805.2A CN201310700805A CN104127263B CN 104127263 B CN104127263 B CN 104127263B CN 201310700805 A CN201310700805 A CN 201310700805A CN 104127263 B CN104127263 B CN 104127263B
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intraocular lenses
multifocal intraocular
optic
slope ring
multifocal
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CN104127263A (en
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郭淑艳
王曌
解江冰
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Abbott (Beijing) Medical Technology Co., Ltd.
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EYEBRIGHT (BEIJING) MEDICAL TECHNOLOGY Co Ltd
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Abstract

The present invention relates to multifocal intraocular lenses.A kind of multifocal intraocular lenses comprises the opticator be made up of optic and optic edge, anterior optic surface and/or optic rear surface arrange diffraction slope ring about the optical axis specular of described multifocal intraocular lenses, the quantity of described diffraction slope ring is between 6-35, wherein the beginning boundary position of the first diffraction slope ring is between 0.580-0.520mm, the end boundary position of the first diffraction slope ring is between 0.815-0.735mm, and the characteristic size of described diffraction slope ring is between 0.125-0.048mm, thus make the aberration of described multifocal intraocular lenses self be zero.Multifocal intraocular lenses of the present invention improves the image quality of multifocal intraocular lenses under polychromatic light condition, strengthens anti-inclination and eccentric characteristic, thus is conducive to obtaining Extra Vision.

Description

Multifocal intraocular lenses
Technical field
The present invention relates generally to the design field of multifocal intraocular lenses.Specifically, the present invention relates to self aberration a kind of is the diffractive multifocal intraocular lenses of zero.
Background technology
Multifocal intraocular lenses is a kind of artificial lens implanting ophthalmic.For those skilled in the art, carrying out diffractive designs on monofocal intraocular lens surface is realize a kind of technological means that multifocal intraocular lenses adopts usually, is called as diffractive multifocal intraocular lenses by the multifocal intraocular lenses designed by this technological means.Diffractive multifocal intraocular lenses an optical surface etches the micro-slope ring that some has the concentric circular character of diffracting power wherein, these micro-slope rings can make the light entering human eye form far and near two focuses simultaneously, and the position of perifocus is determined by additional optical focal power.Fig. 1 is the schematic plan of the diffractive multifocal intraocular lenses 1 observed from the direction, a kind of diffractive multifocal intraocular lenses optic rear surface of prior art.As shown in Figure 1, the form of diffractive multifocal intraocular lenses 1, is normally made up of a circular optical part 2 and the support button loop 5 being arranged on opticator 2 periphery.The opticator 2 of diffractive multifocal intraocular lenses 1 is made up of optic (or effective Optical Region) 3 and optic edge 4, and optic rear surface 6 is provided with diffraction slope ring 8.
Cataract patient is removed cataract by refrangibility cataract operation and is implanted multifocal intraocular lenses, recover postoperative depending near, look the physiological visual function such as far away, photopic vision power and scotopia, its image quality is not only subject to the impact of monochromatic aberration as factors such as spherical aberration, coma, astigmatisms, is also subject to the impact of aberration.People is daily to live in natural environment, the light source received is mainly white light, and it is made up of the monochromatic light of different wave length, and monochromatic light refractive index in same optical medium of different wave length is different, cause the monochromatic light of different wave length to have different focal powers, this phenomenon is called aberration.Aberration makes the focus size of imaging on retina and position change along with the change of wavelength, thus can greatly reduce the quality of polychromatic light object imaging on human eye retina.
Here illustratively, when light is injected into the different material of another kind of optical density by a kind of material, the direction of propagation of its light produces deviation, and this phenomenon is called dioptric phenomenon, diopter represents the size (refractive power) of this dioptric phenomenon, and unit is diopter (being abbreviated as " D ").1D refractive power is equivalent to parallel rays to be focused on 1 meter of focal length.The effect of eyes refracted ray is complained about being wronged light, represents the ability of dioptric, be also called diopter by focal power.Diopter is the refractive intensity of lens for light.Diopter is the size unit of refractive power, represents with D, and both referred to that parallel rays is through this refractive material, the refractive power becoming focus this refractive material when 1M is 1 diopter or 1D.For lens, when referring to the focal length 1M of the unit of power of lens as lens, then the refractive power of this eyeglass is that 1D diopter and focal length are inversely proportional to.The refractive power F=1/f of lens, wherein f is the focal length of lens, in formula: dioptric unit of force is diopter, and symbol is D, and dimension is L -1, 1D=1m -1.
Diffractive multifocal intraocular lenses representative in the market has the ReSTORMultifocalIOL of U.S. Ai Erkang (Alcon) and the TECNISMultifocalIOL of Allergan (AMO).The ReSTORMultifocalIOL refractive index of Alcon is 1.55, and additional optical focal power has 3D(1D, 1 diopter) and 4D two kinds, crystalline lens self has positive aberration; The TECNISMultifocalIOL of U.S.'s Allergan (AMO), refractive index is 1.47, and additional optical focal power is 4D, and this crystalline lens self has negative aberration.
As can be seen here, on market, existing diffractive multifocal intraocular lenses itself is all with certain positive aberration or negative aberration, and then reduces the quality of optical imaging under polychromatic light condition; In addition, because the intraocular lens self of prior art is all with certain aberration, therefore its antagonism is tilted poor with eccentric ability.
Along with the development of monochromatic aberration correcting technology, the importance of aberration constantly manifests, and becomes the obstacle that must overcome obtaining Extra Vision gradually.How by designing intraocular lens's product thus the quality of polychromatic light object imaging on human eye retina can being improved, the problem that those skilled in the art more and more pays close attention to will be become.
Summary of the invention
The present invention proposes in view of the problems referred to above existing in prior art.Inventor is by designing to make the aberration of described multifocal intraocular lenses self be zero to the optic surface of multifocal intraocular lenses innovatively, its object is to improve the image quality of multifocal intraocular lenses under polychromatic light condition, strengthen anti-inclination and eccentric characteristic, thus obtain Extra Vision.
Term definition
The term " optic " (also can being called " effective Optical Region ") used in this application refers to and is positioned at having optical characteristics thus can realizing regulating the part of intraocular lens dioptric major function of intraocular lens's opticator center.Such as, the diameter of the opticator of the intraocular lens used in the embodiment of the present invention is about 6 millimeters, and wherein optic refers to the part within intraocular lens's bore 5.0 millimeters.Certainly, those skilled in the art's easy to understand: be that for the intraocular lens of other size, the intraocular lens's caliber size involved by optic correspondingly may be different, such as, likely slightly larger than 5.0 millimeters for the diameter of opticator.
The term " optic edge " used in this application refers to the marginal area that can not affect the optical characteristics of intraocular lens being arranged on intraocular implants's optic periphery.Such as, the diameter of the opticator of the intraocular lens used in the embodiment of the present invention is about 6 millimeters, and wherein optic edge refers to apart from the circumferential edge part outside 2.5 millimeters, optic center (or intraocular lens's bore 5.0 millimeters).Those skilled in the art's easy to understand: for the intraocular lens that optic diameter is other size, optic edge correspondingly may be different apart from the distance at optic center.
The term " anterior optic surface " used in this application refers to by that intraocular implants's optic surface nearer for tailing edge axis oculi direction distance eye cornea in IOP implantation human eye.
The term " optic rear surface " used in this application refers to that intraocular implants's optic surface relative with above-mentioned intraocular lens's anterior optic surface in intraocular lens.
The term " button loop " used in this application or " support button loop " refer to and are connected with intraocular lens's opticator, not only play the effect of support of optical part but also play the structure of the effect contractility that the contraction of ciliary muscle and varicose produce being delivered to described opticator.
In this application use and represent the term such as " convex " of shape, " recessed " is for longitudinal direction (along the intraocular lens's length direction) central plane of intraocular implants's optic.
The term " ring width of described diffraction slope ring " used in this application refers in optic, a certain difference determining the end boundary position of diffraction slope ring and the vertical dimension of beginning boundary position distance optical axis AO.
The term " the first diffraction slope ring " used in this application refers in multiple diffraction slopes ring of optic, that diffraction slope ring that distance optical axis AO is nearest.
The term " the beginning boundary position of the first diffraction slope ring " used in this application refers to the minimum perpendicular distance of the first diffraction slope ring apart from optical axis AO.
The term " the end boundary position of the first diffraction slope ring " used in this application refers to the maximum normal distance of the first diffraction slope ring apart from optical axis AO.
The term " characteristic size of described diffraction slope ring " used in this application refers in the ring width corresponding to multiple diffraction slopes ring of optic, the minimum ring width of diffraction slope ring.
Specifically, the present invention relates to the content of following many aspects:
1. a multifocal intraocular lenses, described multifocal intraocular lenses comprises the opticator be made up of optic and optic edge,
It is characterized in that,
Anterior optic surface and/or optic rear surface arrange diffraction slope ring about the optical axis specular of described multifocal intraocular lenses, the quantity of described diffraction slope ring is between 6-35, wherein the beginning boundary position of the first diffraction slope ring is between 0.580-0.520mm, the end boundary position of the first diffraction slope ring is between 0.815-0.735mm, and the characteristic size of described diffraction slope ring is between 0.125-0.048mm, thus the aberration of described multifocal intraocular lenses self is made to be zero.
2. the multifocal intraocular lenses according to aspect 1, is characterized in that, described multifocal intraocular lenses be-10-34D depending on distance vision acuity scope and additional optical power range is 3.05-3.95D.
3. the multifocal intraocular lenses according to aspect 1, is characterized in that, described multifocal intraocular lenses be 6-34D depending on distance vision acuity scope and additional optical power range is 3.10-3.80D.
4. the multifocal intraocular lenses according to aspect 1, it is characterized in that, the quantity of described diffraction slope ring is between 6-30, wherein the beginning boundary position of the first diffraction slope ring is between 0.575-0.522mm, the end boundary position of the first diffraction slope ring is between 0.810-0.745mm, and the characteristic size of described diffraction slope ring is between 0.124-0.051mm.
5. the multifocal intraocular lenses according to any one of aforementioned aspect 1-4, is characterized in that, the refractive index preparing material of described multifocal intraocular lenses is between 1.41 to 1.52.
6. the multifocal intraocular lenses according to aspect 5, is characterized in that, described multifocal intraocular lenses is single type intraocular lens or three-member type intraocular lens.
7. the multifocal intraocular lenses according to aspect 5, is characterized in that, the material of preparing of described multifocal intraocular lenses is silica gel, hydrogel, hydrophilic acrylate, hydrophobic acrylic acid's ester or polymethyl methacrylate.
The present invention has following beneficial effect especially:
The multifocal intraocular lenses with zero color difference characteristic of the present invention improves the image quality of multifocal intraocular lenses under polychromatic light condition, strengthens anti-inclination and eccentric characteristic, thus is conducive to obtaining Extra Vision.
Accompanying drawing explanation
According to following accompanying drawing and explanation, feature of the present invention, advantage will become more clear, wherein:
Fig. 1 is the schematic plan of the diffractive multifocal intraocular lenses observed from the direction, a kind of diffractive multifocal intraocular lenses optic rear surface of prior art, and wherein button loop launches and is not folded on the surface of diffractive multifocal intraocular lenses optic;
Fig. 2 is the sectional view with the multifocal intraocular lenses of zero color difference characteristic according to an example of the present invention;
Fig. 3 is optical path difference (Opticalpathdifference, the OPD) schematic diagram of the multifocal intraocular lenses with zero color difference characteristic under 6mm clear aperature near vision polychromatic light condition according to a first advantageous embodiment of the invention;
Fig. 4 is modulation transfer function (Modulationtransferfunction, the MTF) curve synoptic diagram of multifocal intraocular lenses shown in Fig. 3 under near vision polychromatic light condition;
Fig. 5 is the optical path difference schematic diagram of multifocal intraocular lenses under 6mm clear aperature near vision polychromatic light condition with zero color difference characteristic according to a second, preferred embodiment of the present invention;
Fig. 6 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 5 under near vision polychromatic light condition;
Fig. 7 is the optical path difference schematic diagram of the multifocal intraocular lenses with zero color difference characteristic under 6mm clear aperature near vision polychromatic light condition according to the 3rd preferred embodiment of the present invention;
Fig. 8 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 7 under near vision polychromatic light condition;
Fig. 9 is the optical path difference schematic diagram of the multifocal intraocular lenses with zero color difference characteristic under 6mm clear aperature near vision polychromatic light condition according to the 4th preferred embodiment of the present invention;
Figure 10 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 9 under near vision polychromatic light condition;
Figure 11 of the present inventionly has the multifocal intraocular lenses of zero color difference and the MTF correlation curve of the multifocal intraocular lenses with positive aberration and negative aberration of prior art under 6mm clear aperature near vision polychromatic light condition, and wherein curve A shows the MTF of zero color difference intraocular lens under near vision polychromatic light diffraction limit condition; Curve B shows the MTF of zero color difference intraocular lens under near vision polychromatic light condition; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision polychromatic light condition;
Figure 12 be of the present invention there is zero color difference multifocal intraocular lenses and prior art there is positive aberration and the MTF correlation curve of negative aberration multifocal intraocular lenses under near vision polychromatic light condition under eccentric 0.3mm and 0.7mm condition, wherein curve A shows the MTF of zero color difference intraocular lens under near vision polychromatic light condition without acceptance of persons; Curve B shows the MTF of zero color difference intraocular lens under eccentric 0.3mm near vision polychromatic light part; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision eccentric 0.3mm polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision eccentric 0.3mm polychromatic light condition; Curve E shows the MTF of zero color difference intraocular lens under near vision eccentric 0.7mm polychromatic light condition; Curve F shows the MTF of the normsl skin color difference intraocular lens under near vision eccentric 0.7mm polychromatic light condition; Curve G shows the MTF of negative aberration intraocular lens under near vision eccentric 0.7mm polychromatic light condition;
Figure 13 be of the present invention there is zero color difference multifocal intraocular lenses and prior art there is positive aberration and the MTF correlation curve of negative aberration multifocal intraocular lenses under 6mm clear aperature near vision tilts 1 °, 3 °, 5 ° and 7 ° of polychromatic light conditions, wherein curve A shows zero color difference intraocular lens near vision without the MTF under inclination polychromatic light condition; Curve B shows the MTF of zero color difference intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve E shows the MTF of zero color difference intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve F shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve G shows the MTF of negative aberration intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve H shows the MTF of zero color difference intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve N shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve J shows the MTF of negative aberration intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve K shows the MTF of zero color difference intraocular lens under near vision tilts 7 ° of polychromatic light conditions; Curve L shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 7 ° of polychromatic light conditions; Curve M shows the MTF of negative aberration intraocular lens under near vision tilts 7 ° of polychromatic light conditions.
Identical drawing reference numeral is used to represent same or analogous element in the drawing of the present application.
Drawing reference numeral explanation
1 multifocal intraocular lenses
2 opticators
3 optic (or effective Optical Region)
4 optic edge
5 buttons loop
6 optic rear surfaces
7 anterior optic surface
8 diffraction slope rings
The optical axis of AO multifocal intraocular lenses.
Detailed description of the invention
Following specific embodiment is just for explaining explanation further to the present invention further, but the present invention is not limited to following specific embodiments.Any change on these embodiment bases, as long as spirit according to the invention and scope, all will fall in the covering scope of patent of the present invention.
Multifocal intraocular lenses in the embodiment of the present invention is made up of the material of refractive index between 1.41 to 1.52.Certainly, those skilled in the art also can recognize, multifocal intraocular lenses of the present invention can be made up of other conventional materials such as silica gel, hydrogel, hydrophilic acrylate, hydrophobic acrylic acid's ester or polymethyl methacrylates.
The center thickness of the optic of multifocal intraocular lenses of the present invention is in the scope of 0.3 millimeter-1.2 millimeters." center thickness of optic " refers to the thickness in the middle thickness of optic of multifocal intraocular lenses of the present invention.Known for those skilled in the art: the diopter that the size of the center thickness of the optic of multifocal intraocular lenses of the present invention depends on selected material and reaches.
The front surface of the multifocal intraocular lenses optic in the embodiment of the present invention or the face shape of rear surface at least will comprise multi-focal-plane.
Multifocal intraocular lenses in the embodiment of the present invention can be single type intraocular lens, also can be three-member type intraocular lens.
Fig. 2 is the side schematic sectional view with the multifocal intraocular lenses of zero color difference characteristic according to an example of the present invention.
As shown in Figure 2, the optic rear surface 6 of the multifocal intraocular lenses 1 of this example according to the present invention arranges diffraction slope ring 8 about the optical axis AO specular of described multifocal intraocular lenses.In described optic, the quantity of diffraction slope ring is between 6-35, wherein the beginning boundary position of the first diffraction slope ring is between 0.580-0.520mm, the end boundary position of the first diffraction slope ring is between 0.815-0.735mm, and the characteristic size of diffraction slope ring, between 0.125-0.048mm, thus makes the aberration of described multifocal intraocular lenses self be zero in optic.Certainly, those skilled in the art also can recognize: diffraction slope ring 8 also can be so arranged in the anterior optic surface 7 of described multifocal intraocular lenses 1, or can be so arranged on the optic rear surface 6 and anterior optic surface 7 of described multifocal intraocular lenses 1.In described optic, the preferred parameters scope of diffraction slope ring is as follows: in described optic, the quantity of diffraction slope ring is between 6-30, wherein the beginning boundary position of the first diffraction slope ring is between 0.575-0.522mm, the end boundary position of the first diffraction slope ring between 0.810-0.745mm, and in optic the characteristic size of diffraction slope ring between 0.124-0.051mm.
The curvature of described multifocal intraocular lenses anterior optic surface and optic rear surface looks distance vision acuity for multifocal intraocular lenses provides, and its scope is at-10-34D, and preferable range is 6-34D; Depending near optical power be on the basis looking distance vision acuity increase an additional optical focal power; The value size of additional optical focal power is according to the refractive index of intraocular lens, thickness and determining; It is zero color difference that the value of additional optical focal power makes multifocal intraocular lenses of the present invention itself look near, and its scope is generally at 3.05-3.95D, and preferable range is 3.10-3.80D.
Below, choose an example with the multifocal intraocular lenses of zero color difference of the present invention, compare with the comparative example of prior art multifocal intraocular lenses, obtain the correlation curve shown in Figure 11-13.
Example of the present invention:
Material character: refractive index 1.46;
Face shape: biconvex shape, front surface aspheric surface, rear surface sphere, design parameter sees the following form 1.
Additional optical focal power: 3.68D.
Table 1
Parameter Ra/mm Rp/mm T/mm R V Additional optical focal power/D
Optimum embodiment 12.36 -12.06 0.80 1.46 54 3.68
Note: Ra is intraocular implants's body front surface radius of curvature; Rp is intraocular lens rear surface radius of curvature; T is the center thickness of intraocular lens; R is the refractive index of intraocular lens; V is the Abbe number of intraocular lens.
Comparative example:
Positive aberration multifocal intraocular lenses: other parameter of additional optical focal power+3D(is identical with optimum embodiment table 1)
Negative aberration multifocal intraocular lenses: other parameter of additional optical focal power+5D(is identical with optimum embodiment table 1)
Figure 11 of the present inventionly has the multifocal intraocular lenses of zero color difference and the MTF correlation curve of the multifocal intraocular lenses with positive aberration and negative aberration of prior art under 6mm clear aperature near vision polychromatic light condition, and wherein curve A shows the MTF of zero color difference intraocular lens under near vision polychromatic light diffraction limit condition; Curve B shows the MTF of zero color difference intraocular lens under near vision polychromatic light condition; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision polychromatic light condition.
In optometry, object is made up of the sine streak of different space frequency, and when object carries out imaging through opthalmic optics's system, the frequency content of imaging is identical with the frequency content of thing, and the modulation degree of sine streak is different.Here illustratively, spatial frequency F(Spatialfrequency) representation unit is apart from the space periodic number of interior sine streak, and the light and shade striped logarithm (lp/mm) comprised in conventional every millimeter represents.The MTF of optical system refers to the ratio of the modulation degree of the sine streak of different space frequency after optical system and the modulation degree before optical system, its value is between 0-1, reflect the change of sine streak modulation degree corresponding to each frequency content, be the function of spatial frequency, reflect the transmission capacity of optical system to different space frequency.In general, MTF reduces gradually along with the increase of spatial frequency.The high frequency region of MTF describes the details of object, the level of intermediate frequency zone reaction object, and low frequency range describes the profile of object, mtf value is the reaction of human eye to the optical system of different fine degree, be that intraocular lens's optical property is the most comprehensively reacted, be worth larger, represent that optical property is better.Compared to the multifocal intraocular lenses with positive aberration and negative aberration, zero color difference multifocal intraocular lenses mtf value is higher than both.As can be seen here, zero color difference multifocal intraocular lenses can provide better optical quality under near vision polychromatic light condition.
Figure 12 be of the present invention there is zero color difference multifocal intraocular lenses and prior art there is positive aberration and the MTF correlation curve of negative aberration multifocal intraocular lenses under 6mm clear aperature near vision polychromatic light condition under eccentric 0.3mm and 0.7mm condition, wherein curve A shows the MTF of zero color difference intraocular lens under near vision without acceptance of persons polychromatic light condition; Curve B shows the MTF of zero color difference intraocular lens under near vision eccentric 0.3mm polychromatic light part; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision eccentric 0.3mm polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision eccentric 0.3mm polychromatic light condition; Curve E shows the MTF of zero color difference intraocular lens under near vision eccentric 0.7mm polychromatic light condition; Curve F shows the MTF of the normsl skin color difference intraocular lens under near vision eccentric 0.7mm polychromatic light condition; Curve G shows the MTF of negative aberration intraocular lens under near vision eccentric 0.7mm polychromatic light condition.
In the implantation process of intraocular lens, for various reasons, the situation of often Phakic center and pupil center's misalignment occurs, and the size variation of pupil is also eccentric usually.In refractive surgery process, aberration, once bias, will be introduced in lenticular position, reduces image quality.Figure 12 illustrates the MTF curve of zero color difference, positive aberration and negative aberration multifocal intraocular lenses eccentric 0.3mm and 0.7mm under near vision polychromatic light condition.Under identical eccentricity value condition, zero color difference multifocal intraocular lenses under near vision polychromatic light condition mtf value higher than the multifocal intraocular lenses with positive aberration and negative aberration, show that the quality of optical imaging of zero color difference multifocal intraocular lenses is more excellent, there is the characteristic of anti-bias.
Figure 13 be of the present invention there is zero color difference multifocal intraocular lenses and prior art there is positive aberration and the MTF correlation curve of negative aberration multifocal intraocular lenses under 6mm clear aperature near vision polychromatic light condition has a down dip 1 °, 3 °, 5 ° and 7 ° of conditions, wherein curve A shows zero color difference intraocular lens near vision without the MTF under inclination polychromatic light condition; Curve B shows the MTF of zero color difference intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve C shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve D shows the MTF of negative aberration intraocular lens under near vision tilts 1 ° of polychromatic light condition; Curve E shows the MTF of zero color difference intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve F shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve G shows the MTF of negative aberration intraocular lens under near vision tilts 3 ° of polychromatic light conditions; Curve H shows the MTF of zero color difference intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve N shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve J shows the MTF of negative aberration intraocular lens under near vision tilts 5 ° of polychromatic light conditions; Curve K shows the MTF of zero color difference intraocular lens under near vision tilts 7 ° of polychromatic light conditions; Curve L shows the MTF of the normsl skin color difference intraocular lens under near vision tilts 7 ° of polychromatic light conditions; Curve M shows the MTF of negative aberration intraocular lens under near vision tilts 7 ° of polychromatic light conditions.
Similar to the bias of intraocular lens, in refractive surgery process, also can usually there is lenticular rotation phenomenon.Crystalline lens rotates usually with the generation of astigmatism phenomenon.Figure 13 schematically show zero color difference, positive aberration and negative aberration multifocal intraocular lenses and to have a down dip near vision polychromatic light condition the MTF curve of 1 °, 3 °, 5 ° and 7 °.Under identical angle of inclination condition, zero color difference multifocal intraocular lenses at mtf value under near vision polychromatic light condition higher than the multifocal intraocular lenses with positive aberration and negative aberration, show that the optical property of zero color difference multifocal intraocular lenses is better, there is the characteristic of anti-inclination.
The present invention has following beneficial effect especially:
The multifocal intraocular lenses with zero color difference characteristic of the present invention improves the image quality of multifocal intraocular lenses under polychromatic light condition, strengthens anti-inclination and eccentric characteristic, thus is conducive to obtaining Extra Vision.
Embodiment
Below adopt embodiment to be described the multifocal intraocular lenses with zero color difference characteristic of the present invention in further detail, but those skilled in the art can recognize: the present invention is not limited to these embodiments below.
Embodiment 1
Material character: refractive index 1.41;
Face shape: biconvex shape, front surface aspheric surface, rear surface sphere, diffraction slope ring is positioned at rear surface, and design parameter sees the following form 2.
Depending on distance vision acuity: 15D.
Additional optical focal power: 3.05D.
Table 2
Parameter Ra/mm Rp/mm T/mm R V Additional optical focal power/D
Optimum embodiment 9.865 -9.565 1.0 1.41 58 3.05
Note: Ra is intraocular implants's body front surface radius of curvature; Rp is intraocular lens rear surface radius of curvature; T is the center thickness of intraocular lens; R is the refractive index of intraocular lens; V is the Abbe number of intraocular lens.
Because human eye refracting media has natural dispersion characteristics, secondary color white light is after opthalmic optics's system, and optical path difference (unit: wavelength) reaches more than 10 wavelength, can introduce the aberration being greater than 2D, and this will bring certain visual disorder to patient.Fig. 3 is the change schematic diagram of the multifocal intraocular lenses with the zero color difference characteristic according to a first advantageous embodiment of the invention optical path difference under the near vision polychromatic light condition of 6mm entrance pupil aperture along with pupil position, in whole entrance pupil pore diameter range, the optical path difference of 470-650nm wave-length coverage controls within 0.8 wavelength, greatly reduce aberration, improve visual quality; Fig. 4 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 3 under polychromatic light near vision condition.
Embodiment 2
Material character: refractive index 1.45;
Face shape: biconvex shape, front surface aspheric surface, rear surface sphere, diffraction slope ring is positioned on rear surface, and design parameter sees the following form 3.
Depending on distance vision acuity 20D.
Additional optical focal power: 3.23D.
Table 3
Parameter Ra/mm Rp/mm T/mm R V Additional optical focal power/D
Optimum embodiment 11.055 -11.355 0.90 1.45 58 3.23
Note: Ra is intraocular implants's body front surface radius of curvature; Rp is intraocular lens rear surface radius of curvature; T is the center thickness of intraocular lens; R is the refractive index of intraocular lens; V is the Abbe number of intraocular lens.
Fig. 5 is the change schematic diagram of the optical path difference of the multifocal intraocular lenses with zero color difference characteristic according to a second, preferred embodiment of the present invention under the near vision polychromatic light condition of 6mm entrance pupil aperture with pupil position, in whole entrance pupil pore diameter range, the optical path difference of 470-650nm wave-length coverage controls within 0.9 wavelength.Fig. 6 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 5 under polychromatic light near vision condition.
Embodiment 3
Material character: refractive index 1.47;
Face shape: biconvex shape, rear convex, front surface aspheric surface, rear surface sphere, diffraction slope ring is positioned on rear surface, and design parameter sees the following form 4.
Depending on distance vision acuity: 20D.
Additional optical focal power: 3.60D.
Table 4
Parameter Ra/mm Rp/mm T/mm R V Additional optical focal power/D
Optimum embodiment 16.05 -11.10 0.8 1.47 56 3.60
Note: Ra is intraocular implants's body front surface radius of curvature; Rp is intraocular lens rear surface radius of curvature; T is the center thickness of intraocular lens; R is the refractive index of intraocular lens; V is the Abbe number of intraocular lens.
Fig. 7 is according to the change schematic diagram of optical path difference under the near vision polychromatic light condition of 6mm entrance pupil aperture of the multifocal intraocular lenses with zero color difference characteristic of the 3rd preferred embodiment of the present invention with pupil position, in whole entrance pupil pore diameter range, the optical path difference of 470-650nm wave-length coverage controls within 0.9 wavelength.Fig. 8 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 7 under near vision polychromatic light condition.
Embodiment 4
Material character: refractive index 1.52;
Face shape: biconvex shape, rear convex, front surface aspheric surface, rear surface sphere, diffraction slope ring is positioned on rear surface, and design parameter sees the following form 5.
Depending on distance vision acuity: 20D.
Additional optical focal power: 3.95D.
Table 5
Parameter Ra/mm Rp/mm T/mm R V Additional optical focal power/D
Optimum embodiment 27.3 13.40 0.70 1.52 56 3.95
Note: Ra is intraocular implants's body front surface radius of curvature; Rp is intraocular lens rear surface radius of curvature; T is the center thickness of intraocular lens; R is the refractive index of intraocular lens; V is the Abbe number of intraocular lens.
Fig. 9 is the optical path difference schematic diagram of the multifocal intraocular lenses with zero color difference characteristic under the near vision polychromatic light condition of 6mm entrance pupil aperture according to the 4th preferred embodiment of the present invention, in whole entrance pupil pore diameter range, the optical path difference of 470-650nm wave-length coverage is within a wavelength.Figure 10 is the MTF curve synoptic diagram of multifocal intraocular lenses shown in Fig. 9 under near vision polychromatic light condition.
Embodiment is above only illustrative rather than restrictive.Therefore, when not departing from invention disclosed herein design, those skilled in the art can modify to above-described embodiment or change.Therefore, protection scope of the present invention is only limited by the scope of appended claims.

Claims (7)

1. a multifocal intraocular lenses, described multifocal intraocular lenses comprises the opticator be made up of optic and optic edge,
It is characterized in that,
Anterior optic surface and/or optic rear surface arrange diffraction slope ring about the optical axis specular of described multifocal intraocular lenses, the quantity of described diffraction slope ring is between 6-35, wherein the beginning boundary position of the first diffraction slope ring is between 0.580-0.520mm, the end boundary position of the first diffraction slope ring is between 0.815-0.735mm, and the characteristic size of described diffraction slope ring is between 0.125-0.048mm, thus the aberration of described multifocal intraocular lenses self is made to be zero.
2. multifocal intraocular lenses according to claim 1, is characterized in that, described multifocal intraocular lenses be-10-34D depending on distance vision acuity scope and additional optical power range is 3.05-3.95D.
3. multifocal intraocular lenses according to claim 1, is characterized in that, described multifocal intraocular lenses be 6-34D depending on distance vision acuity scope and additional optical power range is 3.10-3.80D.
4. multifocal intraocular lenses according to claim 1, it is characterized in that, the quantity of described diffraction slope ring is between 6-30, wherein the beginning boundary position of the first diffraction slope ring is between 0.575-0.522mm, the end boundary position of the first diffraction slope ring is between 0.810-0.745mm, and the characteristic size of described diffraction slope ring is between 0.124-0.051mm.
5. the multifocal intraocular lenses according to any one of aforementioned claim 1-4, is characterized in that, the refractive index preparing material of described multifocal intraocular lenses is between 1.41 to 1.52.
6. multifocal intraocular lenses according to claim 5, is characterized in that, described multifocal intraocular lenses is single type intraocular lens or three-member type intraocular lens.
7. multifocal intraocular lenses according to claim 5, is characterized in that, the material of preparing of described multifocal intraocular lenses is silica gel, hydrogel, hydrophilic acrylate, hydrophobic acrylic acid's ester or polymethyl methacrylate.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11844688B2 (en) 2019-12-30 2023-12-19 Amo Groningen B.V. Achromatic lenses with zone order mixing for vision treatment

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104783925B (en) * 2015-01-09 2017-01-18 爱博诺德(北京)医疗科技有限公司 Multi-focal artificial lens
EP3130314A1 (en) * 2015-08-12 2017-02-15 PhysIOL SA Trifocal intraocular lens with extended range of vision and correction of longitudinal chromatic aberration
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CA3166089A1 (en) 2019-12-30 2021-07-08 Amo Groningen B.V. Achromatic lenses for vision treatment
CN114041901B (en) * 2021-11-18 2023-03-24 郑州耐视医药科技有限公司 Anti-abrasion multifocal intraocular lens and preparation method thereof
CN115919505B (en) * 2022-11-22 2024-02-06 无锡蕾明视康科技有限公司 Achromatic multifocal intraocular lens

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200426424A (en) * 2002-11-29 2004-12-01 Pharmacia Groningen Bv Multifocal ophthalmic lens
CN1833192A (en) * 2003-06-16 2006-09-13 阿波罗光学系统有限责任公司 Bifocal multiorder diffractive lenses for vision correction
WO2006137355A1 (en) * 2005-06-20 2006-12-28 Riverbell Co., Ltd. Multifocal lens and imaging system
EP1785106A1 (en) * 2003-11-10 2007-05-16 Advanced Medical Optics, Inc. Multi-zonal monofocal intraocular lens
CN101416096A (en) * 2006-02-09 2009-04-22 爱尔康研究有限公司 Pseudo-accomodative iol having diffractive zones with varying areas
CN101422392A (en) * 2007-10-02 2009-05-06 爱尔康公司 Zonal diffractive multifocal intraocular lenses
EP2290411A1 (en) * 2009-08-27 2011-03-02 Polymer Technologies International (EOU) Refractive-diffractive lens
CN102239439A (en) * 2008-12-05 2011-11-09 Hoya株式会社 Diffractive multifocal lens
CN102460272A (en) * 2009-06-09 2012-05-16 诺华公司 Iol with varying correction of chromatic aberration
CN102460274A (en) * 2009-06-09 2012-05-16 诺华公司 Zonal diffractive multifocal intraocular lens with central monofocal diffractive region
CN102947749A (en) * 2010-04-27 2013-02-27 卡尔蔡司医疗技术股份公司 Multifocal lens
WO2013118499A1 (en) * 2012-02-09 2013-08-15 株式会社メニコン Multi-focal optical lens, and manufacturing method for same
WO2013118177A1 (en) * 2012-02-09 2013-08-15 株式会社メニコン Diffraction-type multifocal eye lens and manufacturing method therefor
CN203647536U (en) * 2013-12-19 2014-06-18 爱博诺德(北京)医疗科技有限公司 Multi-focal intraocular lens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1316728C (en) * 1988-04-01 1993-04-27 Michael J. Simpson Multi-focal diffractive ophthalmic lenses
RU2516035C2 (en) * 2009-02-12 2014-05-20 Дзе Аризона Борд Оф Риджентс Он Бихаф Оф Дзе Юниверсити Оф Аризона Diffractive trifocal lens
US20120140166A1 (en) * 2010-12-07 2012-06-07 Abbott Medical Optics Inc. Pupil dependent diffractive lens for near, intermediate, and far vision

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200426424A (en) * 2002-11-29 2004-12-01 Pharmacia Groningen Bv Multifocal ophthalmic lens
CN1833192A (en) * 2003-06-16 2006-09-13 阿波罗光学系统有限责任公司 Bifocal multiorder diffractive lenses for vision correction
EP1785106A1 (en) * 2003-11-10 2007-05-16 Advanced Medical Optics, Inc. Multi-zonal monofocal intraocular lens
WO2006137355A1 (en) * 2005-06-20 2006-12-28 Riverbell Co., Ltd. Multifocal lens and imaging system
CN101416096A (en) * 2006-02-09 2009-04-22 爱尔康研究有限公司 Pseudo-accomodative iol having diffractive zones with varying areas
CN101422392A (en) * 2007-10-02 2009-05-06 爱尔康公司 Zonal diffractive multifocal intraocular lenses
CN102239439A (en) * 2008-12-05 2011-11-09 Hoya株式会社 Diffractive multifocal lens
CN102460274A (en) * 2009-06-09 2012-05-16 诺华公司 Zonal diffractive multifocal intraocular lens with central monofocal diffractive region
CN102460272A (en) * 2009-06-09 2012-05-16 诺华公司 Iol with varying correction of chromatic aberration
EP2290411A1 (en) * 2009-08-27 2011-03-02 Polymer Technologies International (EOU) Refractive-diffractive lens
CN102947749A (en) * 2010-04-27 2013-02-27 卡尔蔡司医疗技术股份公司 Multifocal lens
WO2013118499A1 (en) * 2012-02-09 2013-08-15 株式会社メニコン Multi-focal optical lens, and manufacturing method for same
WO2013118177A1 (en) * 2012-02-09 2013-08-15 株式会社メニコン Diffraction-type multifocal eye lens and manufacturing method therefor
CN203647536U (en) * 2013-12-19 2014-06-18 爱博诺德(北京)医疗科技有限公司 Multi-focal intraocular lens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11844688B2 (en) 2019-12-30 2023-12-19 Amo Groningen B.V. Achromatic lenses with zone order mixing for vision treatment

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