CN107684478A - Region spherical aberration profile astigmatism correction intraocular lens - Google Patents
Region spherical aberration profile astigmatism correction intraocular lens Download PDFInfo
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- CN107684478A CN107684478A CN201710950818.3A CN201710950818A CN107684478A CN 107684478 A CN107684478 A CN 107684478A CN 201710950818 A CN201710950818 A CN 201710950818A CN 107684478 A CN107684478 A CN 107684478A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
- A61F2/164—Aspheric lenses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
- A61F2/1645—Toric lenses
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Abstract
One face of region spherical aberration profile astigmatism correction intraocular lens's opticator of the present invention is astigmatism face, another side is realize spherical aberration correcting function aspherical, the aspherical spherical aberration is being in radially discrete region distribution pattern, astigmatism face is separated with aspherical simultaneously, spherical aberration is radially divided into three different regions, the spherical aberration in each area is respectively set as being fully compensated cornea in small-bore, intermediate pore size and the spherical aberration in large aperture, it is different from what conventional astigmatic corrected intraocular lens, astigmatism correction intraocular lens proposed by the present invention, in different cornea pore diameter ranges, i.e. in photopic vision, under medium vision and noctovision environment, the perfect compensation of corneal spherical aberration can be realized.For the cornea of different astigmatism degrees, the intraocular lens can ensure the image quality of retina in 0 ~ 6mm pore diameter range, and maximum advantage is its visual effect independent of cornea pore size, therefore have very tempting application prospect.
Description
Technical field
New there are region spherical aberration profile astigmatism correction aspheric intraocular lens the present invention relates to a kind of（TIOL）.
This new intraocular lens, the astigmatism brought by eye cornea can be not only compensated, meanwhile, the radial portion of aspherical spherical aberration
Domain is distributed, it is ensured that the image quality under different cornea apertures, so as to finally realize human eye in photopic vision, scotopia and medium
When vision, the stability of visual quality, conventional astigmatic crystalline lens is overcome under scotopia environment, under visual quality is serious
The problem of drop.
Background technology
Cataract has caused the attention of more and more people, with people's age as the main reason for causing people's blinding
Increase, human eye natural lens, which are known from experience, gradually to thicken, or even loses transmittancy, ultimately results in the complete Loss Of Vision work(of human eye
Energy.It is fortunately that under many circumstances, eye lens can be by removal or the implantable artificial crystalline lens of performing the operation, so as to extensive
The eyesight of compound eye eyeball.
Lighttight human lenses are extractd, implantable artificial crystalline lens is the optimal selection for recovering human eye vision, from 1949
Year, Britain used intraocular lens made of hard PMMA materials first, successfully realized lens replacement operation, intraocular implants
Body and corresponding surgical technic have obtained swift and violent development, so far, it is already possible to using flexible material realize single focus,
Refraction, diffractive multifocal and astigmatism correction even zoom IOL, and being successfully applied in clinic.
Refractive power is different on the meridian for eye cornea, and the refractive status for forming two focal lines is referred to as astigmatism, vertically
Meridian and the orthogonal astigmatism of horizontal meridian are referred to as regular astigmatism, account for the 70% of astigmatism, astigmatism two is orthogonal
Meridian be optically referred to as meridian and sagitta of arc direction, the diopter difference between the two directions is referred to as the astigmatism of cornea
Number, typically between 1D ~ 3D.
Fig. 1 is the dioptric schematic diagram of human eye, and from optical angle, human eye is main by cornea a and crystalline lens b two
The optical system of lens composition, pupil c is the aperture diaphragm of whole optical system, and retina d is imaging surface, and whole system is suitable
In being immersed in liquid solution.Cornea assume responsibility for the focal power of eyes more than 2/3rds, crystalline substance as most important optical power element
Shape body undertakes remaining 1/3rd diopter.The cornea of human eye carries certain positivity spherical aberration, and light passes through corneal center area
The refractive power of domain and fringe region is significantly different, and the refractive power of central area is weak, and the refractive power of fringe region is stronger, people
The natural lens of eye can compensate the positive spherical aberration that cornea is brought in itself so that the Integral ball differential of eyes is bordering on zero, therefore, nothing
By bright or in scotopia or at night, all with good visual effect.
The front and rear surfaces of the cornea of normal eye are all similar to sphere, horizontal direction and vertical direction, i.e. meridian and the sagitta of arc
The radius in direction is consistent, and therefore, cornea is essentially identical, ordinary circumstance in the focal power of horizontally and vertically both direction
Under, both differences are less than 0.5D, however, the cornea of also a kind of crowd, the radius of vertical direction is smaller, and the half of horizontal direction
Footpath is larger, so that the focal power of vertical direction is much larger than the focal power of horizontal direction, is formed than more serious astigmatism, caused
The light of infinity can not be focused into clearly as influenceing the visual quality of human eye on the retina.
For the intraocular lens of typical eyes in Fig. 1, the light of infinite far object, thrown in a manner of almost parallel light
Be mapped on human eye, by cornea a, pupil b, and intraocular lens c, be ultimately imaged on the retina d of human eye, along vertical and
The light focusing of horizontal direction is in same point on retina, and so as to blur-free imaging, this is the working method of typical normal eye,
But if when certain astigmatism be present in cornea（Usually preceding surface, regular astigmatism）, as shown in Fig. 2 the diopter edge of cornea
For the angle of entry to being periodic distribution, 90 degree of directions and 180 degree direction correspond to the minimum value and maximum of corneal diopter respectively, right
In normal eye cornea, the contour of diopter angular distribution is circular, i.e., in all directions, the diopter of cornea is one
Cause, difference zero, by figure it can also be seen that the distribution trend of the diopter of cornea radially is consistent, but with pupil
The increase of diameter, the diopter difference of vertical both direction gradually increase, and this is the diopter point of typical regular astigmatism cornea
The maximum and minimum value of cloth situation, i.e. diopter is in 90 degree or 180 degree direction.
When the directional light of infinity is after cornea, because the focal power of vertical both direction is different, along vertical（90 degree of sides
To）And horizontal direction（180 degree direction）Light vertically or horizontal can elongate on the retina, it is difficult to form clearly point
Picture, in order to compensate due to the decline for the image quality that corneal astigmatism is brought, there is the intraocular lens of astigmatism compensation correcting function
Arise at the historic moment, due to corneal astigmatism to be compensated, the focal power of this crystalline lens vertical direction is less than the focal power of horizontal direction, this
A little and eye cornea astigmatism just on the contrary, therefore, after astigmatic intraocular lens implantation human eye, cornea and intraocular lens
It is equal in the focal power sum of horizontal direction in the focal power sum of vertical direction, realize the perfection to eye cornea astigmatism and mend
Repay, finally formed on the retina clearly as.Fig. 3 is a kind of 3 d shape distribution of typical astigmatism correction intraocular lens
Figure, as seen from the figure, the distribution of entire surface shape are similar with eye cornea, 90 degree（270 degree）Directional spreding is precipitous, 0 degree（180 degree）
Direction is gentle, and correspondingly, optical power profile is also angularly to be gradually increased to reduce, the difference of vertical both direction focal power and angle
The vertical both direction diopter difference of film is mutually corresponding.
The astigmatism of eye cornea, aspheric are responsible for correcting in common astigmatism correction intraocular lens, astigmatism face on the market at present
Face carries zero single spherical aberration or certain negative spherical aberration, and for compensating the positivity spherical aberration of eye cornea, Fig. 4 is eye cornea spherical aberration
With pupil radial distribution figure, it can be seen that the distribution of eye cornea spherical aberration is the tradition as pupil size is in non-linear growth
Astigmatism correction intraocular lens generally according to a certain spherical aberration value design, for example, -0.2um or -0.1um etc., this type
The problem of astigmatic intraocular lens, is, because the pupil size of human eye is changed with the change of external environment illumination condition
, if be designed according to certain certain value, at the pupil size of design, image quality can ensure, but once
Pupil size changes, the unavoidable overcompensation of spherical aberration or undercompensation, and therefore, image quality can be entered with the oculopupillary size of people
Row change, patent of the present invention is according to the characteristic distributions of eye cornea spherical aberration, it is proposed that the concept of region spherical aberration, by intraocular lens
Radially it is divided at least threeth area, the spherical aberration in each area is set as that 3mm, 4.5mm and 5.5mm human eye pupil diameters is fully compensated
The spherical aberration value of lower cornea, naturally it is also possible to be set as other spherical aberration values, precondition is being capable of guarantor's eye pupil hole size variation
When image quality.In the case that human eye pupil size changes with ambient lighting situation, due to each region
Spherical aberration is to compensate the spherical aberration of cornea corresponding to the region, thus, there is no overcompensation or under-compensated situation, ensure that human eye
When pupil changes, the stability of human eye vision quality.
The astigmatic intraocular lens that patent of the present invention proposes are to be constructed as below.The one side of optical element is astigmatism face, another
Face face is aspherical.Due to eye cornea in general, the focal power of vertical direction is more than the focal power of horizontal direction, is
The astigmatism that compensation eye cornea is brought, the optical power profiles of the astigmatic intraocular lens of implantation are just mutual with the formation of cornea
Mend, finally in image planes, produce the effect of complementary astigmatism, therefore, the focal power of astigmatic intraocular lens horizontal direction, which is more than, erects
Nogata to focal power, focal power it is larger be cylindrical mirror direction, less is primary mirror direction, under liquid environment, the difference of the two
It is worth the cylindrical mirror degree for astigmatic intraocular lens.The mean value definition of vertical both direction focal power for astigmatic intraocular lens etc.
Focal power is imitated, similar to common aspherical（Sphere）The diopter of intraocular lens.Usual astigmatism correction intraocular lens bends
The scope of luminosity is about 5D to 35D.Cylindrical mirror degree is divided into the different sizes such as 1.5D, 3D, 6D.
In summary, the thinking based on region spherical aberration, present invention proposition is a kind of new to be dissipated with region spherical aberration profile
Light correction type intraocular lens, this new intraocular lens, it can not only correct due to eye cornea vertically and horizontally two
Astigmatism caused by individual direction diopter difference, has been significantly increased the visual quality of human eye, it is often more important that, according to people canthus
The characteristic distributions of film spherical aberration, the creative idea for proposing the matching of region spherical aberration, fundamentally ensure that human eye vision quality with
The stability of pupil change, is a kind of novel astigmatic correction type aspheric intraocular lens for having very much commercial promise.
The content of the invention
Present invention aims at provide a kind of new intraocular lens.With presently commercially available astigmatism correction type aspheric dough figurine
Work crystalline lens is compared, and the new region spherical aberration profile astigmatism correction intraocular lens of the present invention can not only be significantly increased
Image quality of the human eye in the case of photopic vision, noctovision and mesopic vision, and can guarantee that what image quality changed with pupil
Stability, corresponding cataract patient is finally set to obtain higher visual quality.
Specifically, the present invention relates to the content of following many aspects.
1st, it is a kind of that there is region spherical aberration profile astigmatism correction intraocular lens, astigmatism correction type intraocular lens's light
A face of the department of the Chinese Academy of Sciences point is astigmatism face, and shape distribution in face is compound curved surface, and correspondingly, the face shape in another face is region spherical aberration profile
It is aspherical.
2nd, described region spherical aberration profile astigmatism correction intraocular lens, it is characterised in that aspheric intraocular lens
Radially according to spherical aberration size, at least it is divided into three regions.
3rd, described region spherical aberration profile astigmatism correction intraocular lens, it is characterized in that astigmatism face separates with aspherical,
Respectively on two optical surfaces.
4th, described region spherical aberration profile astigmatism correction intraocular lens, its astigmatism face face shape distribution is compound curved surface,
Its face shape distribution meets relationship below：
WhereinZExist for the astigmatism face of artificial lens opticYZThe expression formula of curve in plane,c x Withc y Respectively dissipate
Smooth surfacexDirection andyDirectional curvature radiusR x , R y Inverse,k x Withk y Respectively astigmatism facexDirection andyThe quadratic surface in direction
Constant,yIt is any point on the curve away from axis of abscissas（Z）Vertical range：
。
5th, described region spherical aberration profile astigmatism correction intraocular lens, the aspherical face shape are sat at two-dimentional right angle
Mark system plane（YZ）On curve meet following aspheric curve expression formula：
WhereinZ(y)For artificial lens optic it is asphericalYZThe expression formula of curve in plane,cFor optical section ball
The inverse of curvature radius,kFor aspherical quadratic surface constant,yIt is any point on the curve away from axis of abscissas（Z）'s
Vertical range,A 2i For aspherical high order term coefficient.
6th, described region spherical aberration distribution aspheric intraocular lens, aspherical spherical aberration is multiple spherical aberration values in radial direction
Combination, spherical aberration value is negative, and the cornea positive spherical aberration in the case of different pupil sizes is compensated for full remuneration or part.
7th, described region spherical aberration profile astigmatism correction intraocular lens, wherein constantk<0,k x <0,k y <0。
8th, described region spherical aberration profile astigmatism correction intraocular lens, lenticular face shape can be according to aspherical table
It is determined up to formula linear combination segmentation.
9th, described region spherical aberration distribution astigmatism correction type intraocular lens, it is characterised in that the intraocular lens by
Under intraocular state（35o）Refractive index is the PMMA in the range of 1.49-1.54（Polymethyl methacrylate）Or hydrophobicity propylene
Acid esters or hydrophilic acrylate, are made and the diopter of the intraocular lens is in the range of 5D-35D.
10th, described region spherical aberration profile astigmatism correction intraocular lens, it is characterised in that the intraocular lens's
Astigmatism compensation function realized by compound curved surface structure, the focal power difference of vertical both direction, i.e. cylindrical mirror degree between 1D ~ 6D,
To compensate eye cornea astigmatism 0.7D ~ 4.1D.
11st, described region spherical aberration profile astigmatism correction intraocular lens, the region spherical aberration value of the intraocular lens
It is set in respectively and 3mm is fully compensated, the spherical aberration value of cornea under 4.5mm and 5.5mm human eye pupil diameters.
12nd, region spherical aberration profile astigmatism correction intraocular lens according to any one of the preceding claims, its
It is characterised by, the intraocular lens is single type intraocular lens or three-member type intraocular lens.
Brief description of the drawings
Fig. 1 Liou-Brennan model eye schematic diagrames.
The angular optical power profile figure of Fig. 2 regular astigmatism corneas.
Fig. 3 regions spherical aberration profile astigmatism correction intraocular implants' dignity shape distribution map.
Fig. 4 eye corneas spherical aberrations are with pupil radial distribution figure.
Fig. 5 regions spherical aberration profile astigmatism correction intraocular lens's spherical aberration subregion schematic diagram.
Fig. 6 (a) regions spherical aberration profile astigmatism correction intraocular lens MTF distribution maps, post under different cornea apertures
Mirror degree 3D.
The spherical aberration astigmatism correction intraocular lenses of Fig. 6 (b) zero MTF distribution maps under different cornea apertures, cylindrical mirror degree 3D.
Fig. 7 (a) regions spherical aberration profile astigmatism correction intraocular lens MTF distribution maps, post under different cornea apertures
Mirror degree 6D.
The spherical aberration astigmatism correction intraocular lenses of Fig. 7 (b) zero MTF distribution maps under different cornea apertures, cylindrical mirror degree 6D.
Fig. 8 (a) regions spherical aberration profile intraocular lens is with zero spherical aberration intraocular lens in 100 millimeters of lines to mtf value ratio
Compared with figure, cylindrical mirror degree 3D.
Fig. 8 (b) regions spherical aberration profile intraocular lens is in 100 millimeters of lines to mtf value and diffraction limit comparison diagram, post
Mirror degree 6D.
Embodiment
Specific examples below is only intended to that the present invention is further explained, but the invention is not limited in
Under specific embodiment.Any change on the basis of these embodiments, as long as meeting the spirit and model of the present invention
Enclose, fall within the covering scope of patent of the present invention.
What Fig. 1 was provided is 1997LiouWithBrennanThe simplification phantom eye of proposition, eye model used are to be based onH.L.LiouWithN.A.BrennanArticle " Anatomically accurate, finite model eye for
optical modeling”JOSA A,14(8), 1684-1695。Liou-BrennanEye model has been used corresponding to average
The distance and curvature of the eyes of shape and mean size.The anatomical structure of the very close true human eye of this model, keeps simultaneously
The optical characteristics and aberration characteristics of human eye, the model eye include aspherical corneaa, gradient-index lensbAnd view
Filmc, incident ray enters cornea from infinity to be approximately parallel to optical axis, then by crystalline lens, finally converges in regarding for human eye
On nethike embrane, due to cornea spherical aberration, the ray traveling optical paths close to pupil center are longer, and corresponding focal power is smaller, close to pupil
The ray traveling optical paths of bore edges are shorter, and corresponding focal power is larger, compare in the light of pupil center, rim ray first with optical axis
It is intersecting, thus the spherical aberration of cornea be on the occasion of.
Fig. 2 is astigmatism corneal diopter angularly distribution situation, and as seen from the figure, the diopter of cornea is being angularly week
The distribution of phase property, vertical direction（90 degree of directions and 270 degree of directions）And horizontal direction（0 degree and 180 degree direction）Corresponding angles respectively
The maximum and minimum value of film diopter, the difference of the two is the astigmatism of cornea, for normal eye cornea, diopter angle
It is circular to the contour of distribution, i.e., in all directions, the diopter of cornea is consistent, difference zero, for scattered
For the cornea of light, diopter is periodically variable, maximum and minimum value be present, and the distribution trend of diopter radially is all
Consistent, but as the increase of pupil diameter, the diopter difference of vertical both direction gradually increase, this is that typical rule dissipates
The diopter distribution situation of optic angle film.When astigmatism correction type intraocular lens is implanted into human eye, by the axle position direction of intraocular lens
Overlapped with the vertical direction of cornea, play the effect of corneal astigmatism correction, if axle position direction and cornea vertical direction occur partially
From the compensation effect of intraocular lens declines, and under serious conditions, can lose astigmatism compensation effect.
Fig. 3 is region spherical aberration profile astigmatism correction intraocular lens's compound curved surface that patent of the present invention proposes（Preceding surface）
3 d shape distribution map, as seen from the figure, entire surface shape distribution it is similar with eye cornea, 90 degree（270 degree）Directional spreding
It is precipitous, 0 degree（180 degree）Direction is gentle, and correspondingly, optical power profile is also angularly to be gradually increased to reduce, vertical both direction
The difference of focal power both direction diopter difference vertical with cornea is mutually corresponding.
Fig. 4 be eye cornea spherical aberration with pupil radial distribution figure, under remote imaging contexts, spherical aberration is human eye on axle
The unique aberration of optical system, the size of spherical aberration determine and dominate the image quality of human eye, as seen from the figure, eye cornea
Spherical aberration is as pupil size is in non-linear growth, in the case of aperture ratio is less（Under photopic vision environment）, eye cornea
Spherical aberration is smaller, and with the increase in aperture, change is slower, when the aperture in medium size（Medium visual environment）, human eye
The spherical aberration of cornea starts to increase sharply, and cornea spherical aberration starts to influence the visual quality of human eye, when in large aperture（Scotopia environment
Under）, cornea spherical aberration is bigger, the visual quality of serious deterioration human eye.
Fig. 5 is region spherical aberration profile astigmatism correction intraocular lens's spherical aberration subregion schematic diagram, according to eye cornea spherical aberration
Characteristic distributions, intraocular lens is radially divided at least threeth area, the spherical aberration in each area is set as that 3mm is fully compensated,
The spherical aberration value of cornea under 4.5mm and 5.5mm human eye pupil diameters, it is respectively -0.07um, -0.08um and -0.188um.When
In the case that human eye pupil size changes with ambient lighting situation, because the spherical aberration in each region is to compensate the region
The spherical aberration of corresponding cornea, thus, there is no overcompensation or under-compensated situation, when ensure that the change of human eye pupil, human eye
The stability of visual quality.
Fig. 6（a）For 20D regions spherical aberration profile astigmatism correction intraocular lens, MTF is distributed under different cornea apertures
There is 2.06D astigmatism figure, cylindrical mirror degree 3D, corresponding eye cornea side, useLiouWithBrennanThe simplification phantom eye of proposition is carried out
Calculate, as seen from the figure, based on the aspherical astigmatic intraocular lens of region spherical aberration design, no matter in photopic vision（3mm holes
Footpath）, medium vision（4.5mm aperture）And noctovision（5.5mm）In the case of, the image quality of the sagitta of arc and meridian both direction is all
It is close to diffraction limit, under 3mm apertures, 100mm lines are more than 0.6 to the MTF at place, and under 4.5mm apertures, 100mm lines are to place
MTF be more than 0.7, under 5.5mm apertures, 100mm lines are more than 0.75 to the MTF at place, therefore, in each corresponding aperture
Under, the visual quality of almost Perfect can be realized.
Fig. 6（b）For zero traditional 20D spherical aberration astigmatism correction intraocular lens under different cornea apertures MTF distribution maps, post
Mirror degree 3D, equally, corresponding eye cornea side have 2.06D astigmatism, as seen from the figure, the aspherical astigmatism people of zero spherical aberration design
Work crystalline lens, under 3mm apertures, 100mm lines are more than 0.5 to the MTF at place, under 4.5mm apertures, 100mm lines to the MTF at place not
To 0.2, under 5.5mm apertures, 100mm lines to the MTF at place less than 0.3, in the case of small-bore, image quality or good
, the sagitta of arc and meridian both direction are all close to diffraction limit, but in the case of medium vision, image quality starts significantly
Declining, the image quality of intermediate-frequency section declines particularly evident, and this is due under this aperture, the reason for residual spherical aberration be present,
If further hole diameter enlargement to 5.5mm, residual spherical aberration further increases, image quality is caused further to deteriorate, this is just
Be why common intraocular lens in the case of photopic vision, visual quality is pretty good, once at night in use, once human eye very
The difficult clear basic reason for differentiating object.
Fig. 7（a）For 20D regions spherical aberration profile astigmatism correction intraocular lens, MTF is distributed under different cornea apertures
There is 4.11D astigmatism figure, cylindrical mirror degree 6D, corresponding eye cornea side, as seen from the figure, equally, based on the design of region spherical aberration
Aspherical astigmatic intraocular lens, no matter in the case of photopic vision, medium vision and noctovision, the sagitta of arc and meridian both direction
Image quality be all close to diffraction limit, under 3mm apertures, 100mm lines are more than 0.55 to the MTF at place, in 4.5mm apertures
Under, 100mm lines are more than 0.65 to the MTF at place, and under 5.5mm apertures, 100mm lines are more than 0.7 to the MTF at place, therefore, each
Under aperture corresponding to individual, the spherical aberration of the pore size can be compensated, shows the visual quality of almost Perfect.
Fig. 7（b）For 20D traditional zero spherical aberration astigmatism correction intraocular lens MTF distribution maps, cylindrical mirror under different cornea apertures
6D is spent, equally, there is 4.11D astigmatism corresponding eye cornea side, and as seen from the figure, equally, the aspherical of zero spherical aberration design dissipates
Light intraocular lens, under 3mm apertures, 100mm lines are more than 0.5 to the MTF at place, and under 4.5mm apertures, 100mm lines are to place
MTF is less than 0.3, under 5.5mm apertures, 100mm lines to the MTF at place less than 0.2, in small-bore with 3D cylindrical mirrors degree similarly
In the case of, the image quality of human eye or good, the sagitta of arc and meridian both direction are all close to diffraction limit, but in
In the case of vision, image quality starts to decline to a great extent, and the image quality of intermediate-frequency section declines particularly evident, this be due to
Under this aperture, residual spherical aberration be present, if further hole diameter enlargement to 5.5mm, residual spherical aberration further increases, cause to be imaged
Quality further deteriorates.
Fig. 8（a）For region spherical aberration profile intraocular lens and zero spherical aberration intraocular lens in 100 millimeters of lines to mtf value
Compare figure.Cylindrical mirror degree 3D, abscissa are the pore sizes of cornea, and ordinate is 100 millimeters of lines to mtf value, as seen from the figure,
With the increase in cornea aperture, because the relative aperture of whole opthalmic optics' system is also gradually to increase, opthalmic optics' system
Resolution ratio gradually increases, and is embodied in the mtf value of diffraction limit and gradually increases, for zero spherical aberration astigmatic intraocular lens, in aperture
Under footpath, the mtf value of 100 millimeters of lines pair is still higher, but with the increase in aperture, mtf value rapid decrease, has arrived macropore
In the case of footpath, mtf value declines very serious, can not effectively ensure the visual quality under this aperture, corresponding
Ground, for the spherical aberration profile astigmatism correction intraocular lens of region, mtf value distribution trend and opthalmic optics' system diffraction pole
The distribution trend of limit is very close, and the two has little difference, and with the increase in aperture, the mtf value of 100mm lines pair begins
It is more than 0.4 eventually, the increase in aperture, the image quality of opthalmic optics' system will not be deteriorated, thereby may be ensured that human eye in any hole
Visual quality under the conditions of footpath, this point are very important.
Fig. 8（b）Mtf value is compared in diffraction limit MTF in 100 millimeters of lines for region spherical aberration profile intraocular lens
Figure, cylindrical mirror degree 6D, abscissa are the pore sizes of cornea, ordinate be 100 millimeters of lines to mtf value, similarly, with cornea aperture
Increase, the relative aperture of whole opthalmic optics' system is also gradually to increase, and resolution ratio gradually increases, system diffraction limit
Mtf value gradually increases, for the spherical aberration profile astigmatism correction intraocular lens of region, mtf value distribution trend and people's eye
The distribution trend of system diffraction limit is very close, and the two has little difference, with the increase in aperture, 100mm
The mtf value of line pair is consistently greater than 0.4.
Claims (12)
1. one kind has region spherical aberration profile astigmatism correction intraocular lens, it is characterised in that：The astigmatism correction type is artificial
The face of lens optical part one is astigmatism face, and shape distribution in face is compound curved surface, and correspondingly, the face shape in another face is region ball
Poor profile is aspherical.
2. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：Aspheric dough figurine
Work crystalline lens is at least divided into three regions radially according to spherical aberration size.
3. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：Astigmatism face with
Aspherical separation, respectively on two optical surfaces.
4. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：Its astigmatism face
Face shape distribution is compound curved surface, and its face shape distribution meets relationship below：
WhereinZExist for the astigmatism face of artificial lens opticYZThe expression formula of curve in plane,c x Withc y Respectively astigmatism
FacexDirection andyDirectional curvature radiusR x , R y Inverse,k x Withk y Respectively astigmatism facexDirection andyThe quadratic surface in direction is normal
Number,yIt is any point on the curve away from axis of abscissas（Z）Vertical range.
5. the region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：It is described non-
The face shape of sphere is in two-dimensional Cartesian coordinate system plane（YZ）On curve meet following aspheric curve expression formula：
WhereinZ(y)For artificial lens optic it is asphericalYZThe expression formula of curve in plane,cFor optical section ball
The inverse of curvature radius,kFor aspherical quadratic surface constant,yIt is any point on the curve away from axis of abscissas（Z）'s
Vertical range,A 2i For aspherical high order term coefficient.
6. region spherical aberration according to claim 1 is distributed aspheric intraocular lens, it is characterised in that：Aspherical spherical aberration
In the combination that radial direction is multiple spherical aberration values, spherical aberration value is negative, for being fully compensated or partly compensating different pupil size feelings
Cornea positive spherical aberration under condition.
7. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：Wherein constantk<0,k x <0,k y <0。
8. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：It is lenticular
Face shape can be segmented according to aspherical expression formula linear combination and be determined.
9. the region spherical aberration distribution astigmatism correction type intraocular lens according to claim 1, it is characterised in that：The people
Work crystalline lens is by under intraocular state（35o）Refractive index is the PMMA in the range of 1.49-1.54（Polymethyl methacrylate）Or
Hydrophobic acrylic acid's ester or hydrophilic acrylate, be made and the diopter of the intraocular lens 5D-35D scope
It is interior.
10. the region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：The people
The lenticular astigmatism compensation function of work is realized that the focal power difference of vertical both direction, i.e. cylindrical mirror degree exists by compound curved surface structure
Between 1D ~ 6D, to compensate eye cornea astigmatism 0.7D ~ 4.1D.
11. region spherical aberration profile astigmatism correction intraocular lens according to claim 1, it is characterised in that：The people
The lenticular region spherical aberration value of work is set in respectively is fully compensated 3mm, cornea under 4.5mm and 5.5mm human eye pupil diameters
Spherical aberration value.
12. region spherical aberration profile astigmatism correction intraocular lens according to any one of the preceding claims, its feature
It is：The intraocular lens is single type intraocular lens or three-member type intraocular lens.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111077676A (en) * | 2019-12-10 | 2020-04-28 | 华为技术有限公司 | Astigmatic correction lens, head-mounted display device, and astigmatic correction method |
| CN111796418A (en) * | 2020-07-30 | 2020-10-20 | 杭州明视康眼科医院有限公司 | Diopter calculation method of astigmatic intraocular lens (Toric IOL) |
| CN112426122A (en) * | 2020-11-23 | 2021-03-02 | 张云峰 | Whole-course vision planning method for monofocal intraocular lens |
| CN113367840A (en) * | 2021-08-12 | 2021-09-10 | 微创视神医疗科技(上海)有限公司 | Intraocular lens and method of making same |
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2017
- 2017-10-13 CN CN201710950818.3A patent/CN107684478A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111077676A (en) * | 2019-12-10 | 2020-04-28 | 华为技术有限公司 | Astigmatic correction lens, head-mounted display device, and astigmatic correction method |
| CN111796418A (en) * | 2020-07-30 | 2020-10-20 | 杭州明视康眼科医院有限公司 | Diopter calculation method of astigmatic intraocular lens (Toric IOL) |
| CN111796418B (en) * | 2020-07-30 | 2022-04-26 | 杭州明视康眼科医院有限公司 | Diopter calculation method of astigmatic intraocular lens (Toric IOL) |
| CN112426122A (en) * | 2020-11-23 | 2021-03-02 | 张云峰 | Whole-course vision planning method for monofocal intraocular lens |
| CN112426122B (en) * | 2020-11-23 | 2023-06-09 | 张云峰 | Single focus artificial lens whole course vision planning method |
| CN113367840A (en) * | 2021-08-12 | 2021-09-10 | 微创视神医疗科技(上海)有限公司 | Intraocular lens and method of making same |
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