CN206096074U - A air supply generator for nitrogen dioxide gaseous sterilization - Google Patents

Abstract

The utility model discloses an air supply generator for nitrogen dioxide gaseous sterilization, include: the nitrogen dioxide gas cylinder, with the nitrogen dioxide gas cylinder passes through measurement that gas transmission pipeline connects room in advance, with set up respectively in nitrogen dioxide gas cylinder and the gas bottle warmer that measures in advance the room bottom and room heater in advance, wherein, the last gas mass flow meter that installs of gas transmission pipeline, measure in advance and to install film pressure sensor on the room. The utility model discloses the nitrogen dioxide gas purity of an air supply generator for nitrogen dioxide gaseous sterilization measurement accuracy, safe and reliable, output is high, do not remain in using back gas transmission pipeline, just applicable in the sterilization of different volume containers, can effectively solve among the prior art defect that the nitrogen dioxide gas strength can not the accurate control.

Description

For the air source generator of nitrogen dioxide gas sterilizing

Technical field

This utility model belongs to pharmaceuticals industry sterilization technology field, is related to a kind of gas generating unit, and in particular to a kind of For the air source generator of nitrogen dioxide gas sterilizing.

Background technology

At present, pharmaceuticals industry sterilization method mainly has physical sterilization method and chemical sterilization.

Physical sterilization method includes dry heat sterilization, moist heat sterilization, ray sterilizing, filtration sterilization；Wherein, dry heat sterilization is by thing Product are placed on that baking oven is red to be heated to 160～170 DEG C >=120min, and 170～180 DEG C >=60min or 250 DEG C >=45min this method makes For glass, metal and wooden vessel etc.；Moist heat sterilization is the method sterilized using high steam.Heat sterilization is main It is, using the hydrogen bond in high temperature protein and nucleic acid, to cause nucleic acid damage, protein deformation or solidification, enzyme to lose activity, Microorganism thus it is dead.If the saturated vapor (up to 121.3 DEG C) of gauge pressure 1.05kg/cm2 is through 20min, can kill all of thin Bacterium brood body and spore.This method is mainly used in equipment sterilizing, disinfected, heat-resisting medicated disinfecting etc..Thermodynamics sterilizing application is most Early, effect is most reliable, most popular method.But heat sterilization is not applied to the product of thermal sensitivity.

Ray sterilizing mainly has ultraviolet disinfection, microwave sterilizating, radiation sterilization (the stronger gamma-rays of penetration power and penetration power Weaker β rays)：Ultraviolet can make two thymus pyrimidine covalent bond adjacent on DNA and form dimer, hinder DNA Normal transcription, causes the change XOR of microorganism dead.Ultraviolet penetration power is weaker, simple glass, paper, dust, vapor etc. Shelves ultraviolet can be hindered, the air sterillization of operating room, ward, laboratory is generally used for.Microwave sterilizating is made using high-frequency electric field The sterilizing methods that the polarization of material interior molecules is brought rapidly up, microwave penetration material is allowed to absorb microwave energy, and is converted into heat energy Sterilization functions are presented.Microwave sterilizating is usually used in the sterilizing of oral liquid.Radiation sterilization has lethal effect, antibacterial to various microorganisms Brood body is more sensitive than brood cell to ray.Its mechanism is to direct or through generation free radical, destroys the covalent bond of DNA molecular. γ ray sterilization at least carries out adapting to the verification mode of biological load under 100 grades of gnotobasiss, and sterilize desired environment Cost is higher.Gamma-rays are not suitable for water soluble drug, cause medicine vigor to reduce because producing nontoxic free radical.For Disposable medical plastics article bulk sterile.Biological product, enzyme, vitamin etc. are not suitable for radiation sterilization.

Sterilization by filtration i.e. with screen out or filter material absorption etc. physics mode remove microorganism, be a kind of conventional sterilizing side Method.Filtration is of many uses, and some need the material of sterilizing to be heated, such as many vitamin solutions.Except in beverage, medicine Outer used in production, also normal typical filter method is degerming for air.Sterilization by filtration is used for the filtration sterilization of gas and liquid.

Chemosterilization mainly has gas sterilization and chemical agent bactericidal assay.Many medicines, packaging material etc. can not be carried out The article of physical sterilization, chemosterilization is just especially meaningful as effective supplement of physical sterilization method.Gas sterilization is The method that finger is sterilized with the gas or steam of chemicals.Gas for medicated disinfecting wishes possess following requirements：1. exist Gas or steam can be formed during room temperature；2. penetration power is strong, and the easily distribution in sterilizing thing；3. sterilization functions are fast, toxicity is low, Low concentration just has bactericidal action；4. non-corrosiveness, explosive and zest.

Conventional gaseous sterilization process has ethylene oxide sterilizing, formaldehyde and ozone sterilization.Oxirane is colourless at room temperature, 10.8 DEG C of boiling point.General sterilizing concentration control belongs to wide-spectrum bactericide in 400～800mg/L.Interior needs higher relative humidity (50% or so), can increase sterilization effect.Oxirane tool is flammable, and air content is up to 3.0% (V/ after mixing with air It is explosibility when V).Therefore using when need to be diluted with noble gases carbon dioxide or halogenated hydrocarbons.The control of sterilizing program has certain Difficulty, at 40～60 DEG C, whole sterilization process should be carried out sterilising temp general control under the supervision of person skilled in the art.Sterilizing Afterwards, fresh air should be taken to replace, makes residual ethylene oxide and other effumability residues dissipate.Ventilation and parsing remove residual Stay and be required for 10h or so.

Formaldehyde is also a kind of sterilizing strong broad-spectrum antiseptic body of power, is widely used in the sterilizing of aseptic processing room, per cubic metre Space is with 40% formalin 30ml.But formaldehyde is larger to human injury, sterilizing needs to exclude formaldehyde gases after terminating, during discharge Between generally 20 hours or so, residual is difficult thoroughly to exclude.Formaldehyde finally classifies as a kind of carcinogen by World Health Organization (WHO), This means that the U.S. is currently possible to that use of the world elsewhere to this chemical substance can be followed and send ban.This modification The behavior of decree will cause many industrial departments to go to change their sterilization prediction scheme.

The sterilized form of ozone enzyme 1. needed for oxidation Decomposition antibacterial endogenous glucose.2. directly with antibacterial, virus function, Their organelle of destruction and DNA, RNA, destroy the metabolism of antibacterial.3. invade intracellular, act on the lipoprotein of adventitia With internal lipopolysaccharide, make antibacterial that penetrating sex distortion occur and death is dissolved.Ozone is to the material unprotect surplus after sterilization. Ozone is that toxic gas can excessively make the respiratory system of people obstacle occur, and this requires to seal makes one in ozone excess Long-time was stopped in environment.Ozone is poisonous to people, and safe level is 0.2mg/m3 in national regulation air, therefore sterilization must be Carry out under the conditions of nobody.Ozone is strong oxidizer, there is damage to various article, and concentration is higher to damage heavier to article, can make copper There is green rust staining, ageing of rubber in piece, and discoloration, elasticity lowers, so that become fragile, rupture, make fabric bleaching fade etc..Temperature and wet Degree may affect the bactericidal effect of ozone, and when ozone does the sterilization of water, 0 DEG C preferably, and temperature is higher, is more conducive to dividing for ozone Solution, therefore poorer humidification of bactericidal effect is conducive to the bactericidal action of ozone, requires humidity ＞ 60%, the bigger bactericidal effect of humidity is more It is good.The penetrance of ozone sterilization is poor, and superpower oxidisability causes the compatible very poor of material.

The action principle of hydrogen peroxide is that by complicated chemical reaction dissociation there is highly active hydroxyl to act on cell Film, the protein of its strong oxidizing property destruction composition antibacterial, is allowed to dead.Hydrogen peroxide sterilization it is compatible good, sterilization time is short, Noresidue after sterilizing.But sterilizing still has certain requirement to temperature and humidity, and this is strictly controlled during sterilizing Two parameters, humidity is too high and the too low condensation for easily causing hydrogen peroxide of temperature, substantially reduces sterilization effect.

Chemical reagent mainly includes liquid chlorine, potassium permanganate, chloramines, chlorine dioxide etc..Chemical reagent sterilizes：Troublesome poeration, Fumigation time is long, there is secondary pollution, there is certain harm to human body, on the wall of residue attachment toilet, and equipment On surface, erasing is needed.In several days after sterilization, its suspended particles number can increase.

To sum up told, the gaseous sterilization process that we presently, there are has residue removal difficulty, degraded ventilation time is long, and Capacitive is poor, and humiture has high demands, the problems such as degraded residue removal is difficult.And nitrogen dioxide is a kind of gas of surface sterilizing, no The sealing system of container can be penetrated, and surface residue is seldom, nitrogen dioxide sterilizing is quick sterilization method at normal temperatures, often Warm sterilization process is particularly significant, because the speed that temperature often increases by 10 DEG C of chemical reactions will be doubled, keeps low temperature can ensure that The reaction that degeneration, caking of the minimum degree of medicine etc. may occur.Greatly reduce during nitrogen dioxide sterilization process Sterilizing residue.Nitrogen dioxide can make up the limitation of current conventional sterilization mode.Become development nitrogen dioxide in industry to go out The power of bacterium, such as patent CN102348470A disclose a kind of sterilizing methods, and it is by the sterile chamber to accommodating article subject to sterilization Inside humidified；And it is filled with higher concentration NO₂Gas, to obtain the NO of 9 to 100mg/L in the sterile chamber₂Concentration is carried out Sterilizing.

The filling pressure of nitrogen dioxide gas cylinder only has 0.22Bar (0 DEG C of saturated vapour pressure), and in the situation of pressurization Under be easy to produce polyreaction.It is mixed with its dimeric forms dinitrogen tetroxide under normal circumstances, constitutes a kind of balance State mixture, i.e.,And at present security context monitoring is generally used for using the concentration sensor of nitrogen dioxide, adopt With diffusion type electrochemical toxic gas detector, sample mode is diffusion type, band auxiliary blower.Measurement range is also very limited:It is beautiful Model FGM-3300 measurement range NO of RAE companies of state production₂：0～20ppm；The model of German Drager companies production 6809655 measurement ranges NO2：0～20ppm；And the operation principle of Concentration Testing determines that sensor is not resistant to negative pressure.And When sterilization processes are carried out using nitrogen dioxide, the nitrogen dioxide sterilizing concentration for usually requiring that is 10mg/L, and concentration is after conversion 4870ppm。

Therefore, the injection rate of nitrogen dioxide is ensureing nitrogen dioxide sterilizing air in sterilization container when how precise control sterilizes The concentration of body reaches required value, becomes those skilled in the art's technical barrier urgently to be resolved hurrily at present.

Utility model content

This utility model is solution the problems referred to above of the prior art, it is proposed that a kind of note for being accurately controlled nitrogen dioxide Enter the air source generator for nitrogen dioxide gas sterilizing of amount.

For achieving the above object, this utility model is employed the following technical solutions：

One side of the present utility model is to provide a kind of air source generator for nitrogen dioxide gas sterilizing, bag Include：

Nitrogen dioxide gas cylinder；

The metering pre-chamber being connected by gas pipeline with the nitrogen dioxide gas cylinder；With

It is respectively arranged at the gas cylinder heater and pre- chamber heater of the nitrogen dioxide gas cylinder and metering pre-chamber bottom；

Wherein, gas mass flow gauge is installed on the gas pipeline, diaphragm pressure is installed in the metering pre-chamber Sensor.

Further, the nitrogen dioxide gas cylinder at least two, and be arranged in parallel.

Further, also including the pressure gauge, pressure switch, air relief valve being sequentially arranged on the gas pipeline, One electromagnetic valve, needle-valve and the second electromagnetic valve.

Further, check valve is installed between the nitrogen dioxide gas cylinder and the pressure gauge.

Further, temperature relay and the first temperature probe are installed on the gas cylinder heater, for being precisely controlled The temperature of the nitrogen dioxide gas cylinder.

Further, the vacuum extractor being connected with the metering pre-chamber is also included, the vacuum extractor is included successively Electromagnetic barriers valve, dry vacuum pump, exhaustor and manual ball valve that Jing pipelines connect, for entering to the metering pre-chamber evacuation Row blood pressure lowering simultaneously closes to control NO by electromagnetism needle valve group₂Into the amount of pre-chamber.

Further, the first absorption degradation room is provided between the vacuum extractor and the metering pre-chamber.

Further, the supply list of the nitrogen dioxide gas cylinder, the gas cylinder heater and part gas pipeline composition Unit is positioned in the glove box of tiny structure to prevent the air supply unit from leaking.

Further, be provided with the glove box content of nitrogen dioxide sensor, the second absorption degradation room and for The safe blower fan of negative pressure is set up in the glove box.Content of nitrogen dioxide sensor has when leaking for the air supply unit Sound and light alarm, is mounted with to set up the safe blower fan of negative pressure in the glove box, and absorption degradation room is mounted with before safe blower fan, Just in case there is leakage absorption degradation room by the leakage of the initial stage of absorption, it is to avoid NO₂To environment leakage.

Second aspect of the present utility model is to provide a kind of using the above-mentioned source of the gas for nitrogen dioxide gas sterilizing The bactericidal unit of raw device, the bactericidal unit includes air source generator and sterilization container, and the sterilization container is sent out with the source of the gas The metering pre-chamber connection of raw device.

This utility model adopts above-mentioned technical proposal, compared with prior art, have the following technical effect that：

(1) air source generator for nitrogen dioxide gas sterilizing of the present utility model, in efficiently solving prior art Conversion control from the dinitrogen tetroxide of presence to nitrogen dioxide, sterilize and let out using the measure control of nitrogen dioxide, gas cylinder unit Leakage security control and the problems such as safely providing of source of the gas of sterilizing；

(2) accurate measurement：NO is controlled using air relief valve₂Pressure it is constant, noticeable degree enter metering pre-chamber NO₂Speed, Injection NO is calculated by measuring the pre- indoor pressure change of volume and diaphragm pressure sensor detection metering of pre-chamber₂Amount, together Shi Caiyong gas mass flow gauge checks injection pre-chamber NO₂Quality；

(3) it is safe and reliable：Air supply unit is placed in glove box, real-time by the concentration sensor being arranged on glove box NO in monitoring glove box₂Concentration, in the event of leakage can pass through glove safety shutdown gas cylinder handss valve, it is to avoid gas it is a large amount of Leakage；And using negative pressure is set up in safe blower fan opponent casing, even if the negative relative environment occurred in leakage glove box can Ensure that the safety of operator, the gas of leakage can be used after adsorption chamber reaction of degrading by outside gas discharge chamber Afterwards without residual in gas pipeline；

(4) gas purity is high：Due toIt is a unconditional reversible reaction, but it is favourable to rise gentle blood pressure lowering In gas to NO₂Transformation, this utility model is heated by gas cylinder, and metering pre-chamber evacuation realizes that intensification blood pressure lowering makes N₂O₄To NO₂Turn Change, the thermostatic control for measuring pre-chamber also ensure that NO₂Purity；

(5) standardized designs：Only need to adjust the size and dry vacuum pump of metering pre-chamber according to the volume of sterilization container Exhaust capacity, you can be precisely controlled and enter NO₂Concentration in sterilization container, adapts to the sterilizing of different volumes container.

Description of the drawings

Fig. 1 is a kind of schematic flow sheet of the air source generator for nitrogen dioxide gas sterilizing of this utility model；

Wherein, 1- gas cylinders heater, 2- temperature relays, the temperature probes of 3- first, 4- nitrogen dioxide gas cylinders, 5- gas cylinder handss Valve, 6- check valves, 7- pressure gauges, 8- pressure switches, 9- air relief valve, the electromagnetic valves of 10- first, 11- needle-valves, the electromagnetism of 12- second Valve, 13- gas mass flow gauge, 14- metering pre-chamber, 15- second temperatures probe, 16- diaphragm pressure sensors, 17- it is pneumatic every Film valve, the first absorption degradations of 18- room, 19- electromagnetic barriers valves, 20- dry vacuum pumps, 21- exhaustors, 22- manual ball valves, 23- Pre- chamber heater, the temperature probes of 24- the 3rd, 25- content of nitrogen dioxide sensors, the second absorption degradations of 26- room, 27- safety winds Machine.

Specific embodiment

This utility model is described in more detail below by specific embodiment, for a better understanding of this reality With new, but following embodiments are not intended to limit this utility model scope.

Embodiment 1 as shown in figure 1, present embodiments provide it is a kind of for nitrogen dioxide gas sterilizing air source generator, The air source generator mainly includes：Nitrogen dioxide gas cylinder 4；The metering pre-chamber being connected by gas pipeline with nitrogen dioxide gas cylinder 4 14；Gas cylinder heater 1 and pre- chamber heater 23 that respectively nitrogen dioxide gas cylinder 4 and metering pre-chamber 14 are heated, and by gas It is 45 DEG C that bottle warmer 1 and pre- chamber heater 23 are controlled to nitrogen dioxide gas cylinder 4 and the temperature of metering pre-chamber 14, realizes that balance is anti- ShouldThe stable conversion of positive direction, constitutes the air source generator for nitrogen dioxide gas sterilizing of the present embodiment, Directly air source generator can be connected with medical sterile chamber, using the NO of the concentration known in metering pre-chamber 14₂It is passed through medicine to go out In bacterium room, sterilization processes are carried out.

Wherein, gas cylinder handss valve 5 and check valve 6 are installed in the nitrogen dioxide gas cylinder 4, prevent extraneous gas from entering nitrogen oxide Gas cylinder 4；The temperature probe 3 of temperature relay 2 and first is installed on gas cylinder heater 1, for being precisely controlled titanium dioxide nitrogen The temperature of bottle 4.Meanwhile, second temperature probe 15 and diaphragm pressure sensor 16 are also equipped with metering pre-chamber 14, in pre-chamber Heater 23 is provided with the 3rd temperature probe 24, to realize the temperature precise control to measuring pre-chamber 14.

Embodiment 2 a kind of can precisely measure being used for for sterilizing content of nitrogen dioxide as shown in figure 1, present embodiments providing The air source generator of nitrogen dioxide gas sterilizing, the air source generator mainly includes：Nitrogen dioxide gas cylinder 4；With titanium dioxide nitrogen The metering pre-chamber 14 that bottle 4 is connected by gas pipeline；Respectively nitrogen dioxide gas cylinder 4 and the gas cylinder of the metering heating of pre-chamber 14 add Hot device 1 and pre- chamber heater 23, and nitrogen dioxide gas cylinder 4 and metering are controlled to by gas cylinder heater 1 and pre- chamber heater 23 The temperature of pre-chamber 14 is 45 DEG C, realizes balancing responseThe stable conversion of positive direction.

NO during to realize being precisely controlled sterilizing₂Concentration, on the basis of above-described embodiment 1, be provided with gas pipeline Gas mass flow gauge 13, and diaphragm pressure sensor 16 is installed in metering pre-chamber 14, by the volume for measuring pre-chamber 14 With the NO that the pressure change of the metering pre-chamber 14 detected by diaphragm pressure sensor 16 reaches control injection metering pre-chamber 14₂'s The purpose of amount, referring concurrently to the meter of gas mass flow 13 NO of injection metering pre-chamber 14 is checked₂Amount.

Preferably, be also equipped with gas pipeline pressure gauge 7, pressure switch 8, air relief valve 9, the first electromagnetic valve 10, The electromagnetic valve 12 of needle-valve 11 and second.Constitute the source of the gas for nitrogen dioxide gas sterilizing that can precisely measure sterilizing of the present embodiment Generator, directly can be connected air source generator with medical sterile chamber, using the NO of the concentration known in metering pre-chamber 14₂It is passed through Medicine sterilizing is indoor, carries out sterilization processes.

The present embodiment controls NO using air relief valve 7₂Pressure it is constant, needle-valve 11 control enter metering pre-chamber 14 in NO₂Speed Degree, by the pressure change in the volume and diaphragm pressure sensor 16 detection metering pre-chamber 14 for measuring pre-chamber 14 injection is calculated NO₂Amount, while using gas mass flow gauge 13 check injection metering pre-chamber 14 in NO₂Quality.

Specifically, the NO in injection metering pre-chamber 14₂The computing formula of amount be：

P1*V1=P2*V2；V=V1-V2；P1*V=n*R*T；

Wherein, n is NO₂Amount；P1 is to measure the pressure before pre-chamber evacuation；P2 is to measure the pressure after pre-chamber evacuation Power；V1 is to measure the gas volume before pre-chamber evacuation；V2 is to measure the original gas volume after pre-chamber evacuation；V is true to take out The NO of injection metering pre-chamber after sky₂Volume；R is ideal gas constant；T is to measure the temperature after pre-chamber evacuation.

Embodiment 3 is as shown in figure 1, present embodiments provide a kind of raising with injection content of nitrogen dioxide for dioxy Change the air source generator of nitrogen sterilizing, specifically, as different from Example 2：The present embodiment is by metering pre-chamber 14 Vacuum extractor is provided with, vacuum extractor is used to carry out blood pressure lowering to promote to measure in pre-chamber 14 to measuring the evacuation of pre-chamber 14The stable conversion of positive direction, and NO is provided by way of blood pressure lowering₂Transfer of the gas from gas cylinder to pre-chamber.

To ensure to use safety in vacuum, prevent from measuring the nitrogen dioxide leakage in pre-chamber 14, it is true taking out The first absorption degradation room 18 is provided between empty device and metering pre-chamber.And the first absorption degradation room 18 and metering pre-chamber 14 it Between pipeline on pneumatic diaphragm valve 17 is installed.The vacuum extractor is by electromagnetic barriers valve 19, dry vacuum pump 20, exhaustor 21 Constitute with manual ball valve 22.

Specifically, the present embodiment in order to metering pre-chamber 14 highly purified NO2 gases are provided, by control dry vacuum Pump 20,17 pairs of metering pre-chamber 14 of electromagnetic barriers valve 19 and pneumatic diaphragm valve carry out evacuation, and the vacuum measured in pre-chamber 14 is led to The detection control of diaphragm pressure sensor 16 is crossed, electromagnetic barriers valve 19, pneumatic diaphragm valve 17 is closed when vacuum reaches setting value And dry vacuum pump 20.

Embodiment 4 present embodiments provides a kind of safe and reliable to prevent nitrogen dioxide from revealing for nitrogen dioxide gas The air source generator of sterilizing, on the basis of above-described embodiment 1, embodiment 2 or embodiment 3, nitrogen dioxide gas cylinder 4, for dioxy Change the gas cylinder heater 1 and part gas pipeline composition air supply unit of the heating of nitrogen cylinder 4, as shown in Fig. 1 dotted portions, supply Unit is positioned in glove box to prevent air supply unit from leaking, part gas pipeline including be provided with pressure gauge 7, pressure after The gas pipeline of electrical equipment 8, the electromagnetic valve 10 of air relief valve 9 and first.

By installation content of nitrogen dioxide sensor 25, the second absorption degradation room 26 on glove box and in glove box The safe blower fan 27 of negative pressure is inside set up, ensures to supply to carry out the leakage situation of air supply unit real-time monitoring and carry out degradation treatment Using for gas unit is safe.

Embodiment 5 present embodiments provides a kind of air source generator for nitrogen dioxide gas sterilizing, in above-mentioned enforcement On the basis of example 1, embodiment 2, embodiment 3 or embodiment 4, as shown in figure 1, nitrogen dioxide gas cylinder 4 at least two and parallel connection The plenum system of setting, prevents one bottle of gas to be finished, and the situation about terminating that sterilizes occurs.

Embodiment 6 is used for application of the air source generator of nitrogen dioxide gas sterilizing in medicine sterilizing or sterilizing installation. Wherein, the NO in injection metering pre-chamber 14₂The computing formula of amount be：

P1*V1=P2*V2；V=V1-V2；P1*V=n*R*T.

Pre- building volume is designed as 5L, and pre-chamber is evacuated to 300Pa by pre-chamber steady temperature at 45 DEG C, is filled with pressure after NO2 Rise to 3000Pa；

So original gas is according to formula：P1*V1=P2*V2

5L*300Pa=3000Pa*V2 V2=0.5L, then the NO2 volumes of injection are V=5-0.5=4.5L, pressure V =3000Pa；

Then basis：P*V=n*R*T

3000Pa*4.5/1000, m3=n mol*8.31 (Pa*m3*mol-1*K-1) * (273+45) K, n= 0.0051mol, draws NO₂Mass M=0.0051mol*46g/mol=0.235g；

The sterilizing concentration for setting is as 10mg/L, then the NO of injection₂The overall vessel volume V of the sterilizing installation of gas is total= 0.235*1000/10=23.5L (space sterilization container of this volume comprising NO2 injections in all sterilization process, pre-chamber, pipeline, Valve etc.).

Additionally, this utility model proves that temperature is raised and reduced pressure is to promote balancing response using testCarry out to positive direction.According to NO₂Boiling point be 21.2 DEG C, this utility model is pacified outside nitrogen dioxide gas cylinder 4 Gas cylinder heater 1 is filled and has controlled by the first temperature probe 3 heating-up temperature (the heating of general setting of nitrogen dioxide gas cylinder 4 Temperature is 45 DEG C), temperature relay 3 is the gas cylinder heater failure for preventing nitrogen dioxide gas cylinder 4, and temperature heats too high protection Device.Because the pressure ratio of nitrogen dioxide gas cylinder 4 is relatively low, when system pours compressed air, check valve 6 avoids extraneous gas from entering Nitrogen dioxide gas cylinder 4, it is ensured that the gas purity in nitrogen dioxide gas cylinder 4.Can lead in the heating process of nitrogen dioxide gas cylinder 4 Excess pressure table carrys out gas pressure in 7 observation nitrogen dioxide gas cylinders 4, if meet sterilization pressure by set by pressure transducer 8 Value judges.

In order to stablize the pressure of source of the gas nitrogen dioxide gas cylinder 4, source of the gas air relief valve 9 is mounted with gas pipeline.Supply is single Unit realizes with the switch for connecting through the first electromagnetic valve 10 of metering pre-chamber 14.In order to provide highly purified NO₂Gas, passes through Dry vacuum pump 20, electromagnetic barriers valve 19, the control of pneumatic diaphragm valve 17 carry out evacuation, vacuum to sterilizing metering pre-chamber 14 Controlled by diaphragm pressure sensor 16, when vacuum reaches setting value, close electromagnetic barriers valve 19, pneumatic diaphragm valve 17 and do Formula vacuum pump 20.The volume of metering pre-chamber 14 calculates that (volume size is according to being sterilized volume of a container by 10- through accurate 90mg/L concentration is calculated needs NO₂Consumption is determining).In order to preventConversion, the metering of pre- chamber heater 23 pairs Pre-chamber 14 is heated, and the 3rd temperature probe 24 is monitored to heating-up temperature, second temperature 15 monitoring and metering pre-chamber 14 of probe Interior NO₂Temperature.

In order to prevent air supply unit from leaking, whole air supply unit is placed in glove box, such as Fig. 1 dotted portions, Safe blower fan 27 sets up negative pressure in glove box.If there is leakage, the second absorption degradation room 26 before safe blower fan 27 in system Understand the nitrogen dioxide of absorption degradation leakage, in addition nitrogen dioxide in the sense of content of nitrogen dioxide sensor 25 real-time monitoring glove box Concentration；If nitrogen dioxide gas cylinder 4 has leakage, content of nitrogen dioxide sensor 25 senses the content of nitrogen dioxide in glove box More than sound and light alarm will be produced during secure setting.Now the top of nitrogen dioxide gas cylinder 4 can be closed by the glove of glove box Gas cylinder handss valve 5, it is to avoid the more nitrogen dioxide of leakage, it is ensured that air supply unit using safety.

Certain density NO is injected in order to accurately measure in pre-chamber 14 to sterilizing₂, needle-valve 11 is mounted with gas pipeline For adjusting the speed of gas entrance, NO₂Injection rate controlled by gas mass flow gauge 13 first.NO₂Injection rate also Calculated according to The Ideal-Gas Equation by the pressure rise value of the monitoring and metering pre-chamber 14 of 6 diaphragm pressure sensor 1.

Specific embodiment of the utility model has been described in detail above, but it is intended only as example, and this practicality is new Type is not restricted to particular embodiments described above.To those skilled in the art, it is any that this utility model is carried out Equivalent modifications and substitute also all among category of the present utility model.Therefore, without departing from spirit of the present utility model and model Enclose lower made impartial conversion and change, all should cover in the range of this utility model.

Claims (10)

1. it is a kind of for nitrogen dioxide gas sterilizing air source generator, it is characterised in that include：

Nitrogen dioxide gas cylinder；

The metering pre-chamber being connected by gas pipeline with the nitrogen dioxide gas cylinder；With

It is respectively arranged at the gas cylinder heater and pre- chamber heater of the nitrogen dioxide gas cylinder and metering pre-chamber bottom；

Wherein, gas mass flow gauge is installed on the gas pipeline, diaphragm pressure sensing is installed in the metering pre-chamber Device.

2. it is according to claim 1 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that the dioxy Change nitrogen cylinder at least two, and be arranged in parallel.

3. it is according to claim 1 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that also include according to Secondary pressure gauge on the gas pipeline, pressure switch, air relief valve, the first electromagnetic valve, needle-valve and the second electromagnetic valve.

4. it is according to claim 3 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that the dioxy Change and check valve is installed between nitrogen cylinder and the pressure gauge.

5. it is according to claim 1 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that the gas cylinder Temperature relay and the first temperature probe are installed, for being precisely controlled the temperature of the nitrogen dioxide gas cylinder on heater.

6. it is according to claim 1 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that also include with The vacuum extractor of the metering pre-chamber connection.

7. the air source generator for nitrogen dioxide gas sterilizing according to claim 6, it is characterised in that described to take out true Empty device includes the electromagnetic barriers valve of Jing pipelines connection, dry vacuum pump, exhaustor and manual ball valve successively.

8. the air source generator for nitrogen dioxide gas sterilizing according to claim 6, it is characterised in that described to take out true The first absorption degradation room is provided between empty device and the metering pre-chamber.

9. it is according to claim 1 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that the dioxy Change nitrogen cylinder, the air supply unit of gas cylinder heater and part gas pipeline composition be positioned in the glove box of tiny structure with Prevent the air supply unit from leaking.

10. it is according to claim 9 for nitrogen dioxide gas sterilizing air source generator, it is characterised in that the handss Content of nitrogen dioxide sensor, the second absorption degradation room and the peace for setting up negative pressure in the glove box are installed on casing Full blast machine.