CN102363045B - Composite disinfecting and sterilizing device and method - Google Patents

Composite disinfecting and sterilizing device and method Download PDF

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Publication number
CN102363045B
CN102363045B CN 201110318295 CN201110318295A CN102363045B CN 102363045 B CN102363045 B CN 102363045B CN 201110318295 CN201110318295 CN 201110318295 CN 201110318295 A CN201110318295 A CN 201110318295A CN 102363045 B CN102363045 B CN 102363045B
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cabin
electromagnetic valve
cabin body
sterilization
ozone
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CN102363045A (en
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罗二平
申广浩
徐巧玲
谢康宁
路丽华
刘娟
吴小明
汤池
闫一力
孙涛
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Abstract

The invention discloses a composite disinfecting and sterilizing device and method. The composite disinfecting sterilizing device comprises a cabin body, wherein a temperature, ozone concentration and humidity sensor is arranged at the top of the cabin body; a barometric pressure sensor is arranged at the bottom of the cabin body; an oxygen source is communicated with the interior of the cabin body through an ozone generator via a fourth solenoid valve; an ultrasonic humidifier is communicated with the interior of the cabin body through a second solenoid valve; a heating element is arranged at the outer side of the cabin body; one end of a peristaltic pump is communicated with H2O2; the other end of the peristaltic pump is communicated with the interior of the cabin body through a third solenoid valve; high-voltage electrode plates are oppositely arranged at two sides on the inner wall of the cabin body; and a vacuum pump is connected with the cabin body through a first solenoid valve. The disinfecting and sterilizing method comprises two alternative modes of low-temperature plasma composite hydrogen peroxide and ozone; the whole disinfecting process is intelligently controlled; and the invention has the advantages of wide application range, high sterilization speed, high inactivation ratio, no residual harm or disinfecting dead corners, convenience for use, high automatic degree and the like.

Description

A kind of composite disinfecting bactericidal unit and method
Technical field
The present invention relates to a kind of disinfector for medical treatment and adopt the method for disinfection and sterilization of this device.
Background technology
1, traditional thermal sterilization technology
Traditional pasteurization is a kind of effective method for disinfection, and it can kill various microorganisms, and the sterilization degree can accurately be controlled.Although the thermal sterilization method is widely used, the required high temperature of the method easily causes the thermal sensitivity composition to decompose and volatile ingredient scatters and disappears, and energy consumption is also higher, is easy to damage accurate Medical Instruments.
2, non-thermal sterilization technology
(1) ultraviolet: can kill various microorganisms, comprise bacterial propagule, brood cell, mycobacterium, virus, fungus, rickettsia and mycoplasma etc., have broad spectrum activity.Its sterilizing mechanisms is by the irradiation of ultraviolet to microorganisms such as antibacterial, viruses, to destroy the structure of DNA in its body (deoxyribonucleic), makes its immediately dead or forfeiture fertility.DNA absorbs the strongest to the purple of wavelength 254nm.The ultraviolet light decay is larger, and the life-span is not long; Ultraviolet bactericidal effect and its exposure rate and total irradiation dose are relevant.Ultraviolet can only be along straightline propagation, and emittance is low, a little less than the penetration power, only can kill the microorganism that shines directly into, because ultraviolet radiation has injury to human body, has therefore allowed anything but leakage.
(2) oxirane: broad-spectrum biocide, Bactericidal Mechanism mainly are the cellular metabolisms of its destruction thalline that combines with molecule in the antibacterial.Have advantages of without dead angle, penetration power stronger.But inflammable and explosive, poisonous, have residual.
(3) ozone: ozone is a kind of wide-spectrum bactericide, ozone when spatial diffusion, can rapid permeability to the cell wall of miscellaneous bacteria thalline and microorganism, make its albuminous degeneration, the destructive enzyme system stops metabolic process and is killed.At present, ozone is most widely used in all trades and professions.The sterile environment temperature is higher, humidity is less, and ozone more easily is reduced into oxygen, and Disinfection Effect is poorer; Accurate small-sized medical instrument can not be used ozonization, very easily corrosion; A little less than the penetration power of ozone, low to object vertical-depth killing bacteria ability.
(4) hydrogen peroxide: the mechanism and the ozone that act on microorganism are similar.The one, oxidisability makes molecule or atomic ionization, thereby the fat chain changes the cell wall permeability and causes cell death on the destruction cell wall, the 2nd, hydrogen peroxide enters thalline and can react with metal ion in the nucleic acid, produce the toxicity hydroxyl, the phosphodiester bond that acts on DNA makes its fracture, and four kinds of base compositions of DNA are had destruction.Temperature, humidity, Organic substance are all influential to the sterilization of hydrogen peroxide.
(5) low Temperature Plasma Sterilization Technology: be a kind of new physical sterilization technology of field of disinfection and sterilization in recent years.Low-temperature plasma is specially adapted to nonrefractory and to wet heat sensitive sterilization.But low-temperature plasma also has its limitation, and for example following article should not use the material of Low Temperature Plasma Sterilizers: 1. disposable using apparatus and article; 2. liquid or powder; 3. wooden apparatus; 4. bafta; 5. gauze; 6. not exclusively dry article.
At present, both at home and abroad sterilization equipment function singleness is carried out decontamination mainly for certain apparatus or material, and complex structure, fault rate are high, and environmental suitability is poor.
Summary of the invention
In view of the existing deficiency of above existing decontamination equipment, and consider that the different infectious diseases pathogen respectively has characteristics, different to the toleration of different sterilization methods, in order to strengthen decontaminating effect, the invention provides the compound bactericidal unit of a kind of many sterilizations pattern.
For reaching above purpose, the present invention takes following technical scheme to be achieved:
A kind of composite disinfecting bactericidal unit is characterized in that, comprises the cabin body, source of oxygen, peristaltic pump, humidifier and vacuum pump, and body top, described cabin is provided with temperature sensor, ozone concentration sensor and humidity sensor; Body bottom, cabin is provided with baroceptor; Described source of oxygen by ozonator within the 4th electromagnetic valve leads to the cabin body; Described ultrasonic humidifier is within the second electromagnetic valve leads to the cabin body; The external side in cabin is provided with the heating element heater that can heat the cabin body; Described peristaltic pump one end is communicated with H 2O 2, the other end is in the 3rd electromagnetic valve passes into the cabin body; The opposed electrode plate with high voltage that is equipped with in body inwall both sides, cabin, described vacuum pump connects through the first electromagnetic valve and cabin bulk phase.
A kind of method that adopts said apparatus to realize sterilization comprises the steps:
(1) in the body of cabin, puts into the article that are sterilized, device is powered up startup;
(2) select the sterilization pattern: in " the compound hydrogen peroxide of low-temperature plasma " and " ozone " two kinds of patterns, select one, wherein,
A, when selecting " the compound hydrogen peroxide of low-temperature plasma " sterilization pattern, the cabin body is heated by heating, to 47-56 ℃, open the first electromagnetic valve, by the vacuum pump evacuation, the cabin bromhidrosis is forced down behind 2000 handkerchiefs the first closed electromagnetic valve, open the 3rd electromagnetic valve, close the 3rd electromagnetic valve after injecting a small amount of hydrogen peroxide by peristaltic pump, make hydrogen peroxide be condensed into vaporific at the cabin internal diffusion; Secondary is opened the first electromagnetic valve, start and close the first electromagnetic valve when vacuum pump is evacuated to the 39-45 handkerchief, secondary is opened the 3rd electromagnetic valve and is repeated to inject hydrogen peroxide less than the injection rate first time, then close the 3rd electromagnetic valve, again open the first electromagnetic valve and continue evacuation, detect in real time pressure in the body of cabin by pressure transducer, make it maintain the 80-200 handkerchief, load high-voltage pulse to electrode plate with high voltage this moment, the hydrogen peroxide of disperse is under the excitation of high electric field in the body of cabin, be provoked into plasma state, act on uniformly the article that are sterilized;
B, when selecting " ozone " disinfection way, detect temperature in the cabin by temperature sensor, when temperature is lower than 25 ℃, humidity sensor detects the humidity in the body of cabin, when humidity less than 80% the time, ultrasonic humidifier starts, the second electromagnetic valve is opened, steam enters humidification in the cabin, when humidity was higher than 80%, (oxygen produced ozone by ozonator to source of oxygen, and the 4th electromagnetic valve is opened, ozone enters in the body of cabin, carries out the disperse sterilization.
In the said method, the described high-voltage pulse that electrode plate with high voltage is loaded is 3000 volts.The ozone that described ozonator produces, its concentration is higher than 40mg/L.The described amount of injecting for the first time hydrogen peroxide by peristaltic pump is 4 milliliters; The amount of injecting for the second time hydrogen peroxide is 2.5 milliliters.
Compared with prior art, three kinds of modes such as the comprehensive ozone of the present invention, hydrogen peroxide and low-temperature plasma (clinically to medical article three kinds of fire brigades commonly used), adopt selectable two kinds of sterilization patterns, the intelligent control of whole disinfecting process, have applied widely, sterilization speed is fast, inactivation ratio is high, without torture, without sterilization dead angle, easy to use, automaticity advantages of higher.Not only satisfied the decontamination (ozone) of medical cotton fabric product, and can carry out disinfection to medical apparatus and instruments (under nearly vacuum state, hydrogen peroxide is excited into plasma, strengthened sterilization effect), to common tract type medical apparatus and instruments, such as endoscope, respirator etc., decontaminating effect is good.
Description of drawings
Below in conjunction with the drawings and the specific embodiments the present invention is helped the well detailed description in one step.
Fig. 1 is apparatus of the present invention structural representation.Among the figure: 1, ultrasonic humidifier; 2, H 2O 2Peristaltic pump; 3, electromagnetic valve; 4, humidity sensor; 5, O 3Concentration sensor; 6, temperature sensor; 7, electromagnetic valve: 8, electromagnetic valve; 9, ozonator; 10, oxygen cylinder; 11, electrode plate with high voltage; 12, baroceptor; 13, vacuum pump; 14, electromagnetic valve: 15, cabin body.
Fig. 2 is for adopting the sterilization flow chart of Fig. 1 device.
The specific embodiment
As shown in Figure 1, a kind of composite disinfecting bactericidal unit comprises cabin body 15, and 3 sensors are equipped with at body top, cabin: temperature sensor 6, ozone concentration sensor 5 and humidity sensor 4; A baroceptor is equipped with in body bottom, cabin.Oxygen cylinder 10 connects ozonator 9, to produce high-concentrated ozone, leads to sterilizing cabin body 15 through electromagnetic valve 7 (normally closed); Ultrasonic humidifier 2 (containing pure water box) is led in the cabin through electromagnetic valve 3 (normally closed) by pipeline, to the high humidity environment of cabin body humidification with the generation ozonization.The external side in cabin is wound with resistance wire (not shown in FIG.), can heat aluminum cabin body, reaches the temperature environment of hydrogen peroxide activated plasma.Peristaltic pump 2 one termination hydrogen peroxide H 2O 2(bottled), an end passes into the cabin body through electromagnetic valve 8 (normally closed), quantitatively to supply with hydrogen peroxide in the cabin.Body inwall both sides, cabin are opposed is equipped with two electrode plate with high voltage 11, to produce high pressure in the body of cabin, excites to produce hydrogen peroxide and produce plasma.
Vacuum pump 13 by the rustless steel pipeline through electromagnetic valve 14 (normally closed) connecting cabin body, can be to evacuation in the cabin, reach the nearly vacuum environment (negative pressure ventilation is removed the molecule of each component of air) that hydrogen peroxide plasma produces, at this moment, cabin endoperoxides hydrogen molecule is excited by the high energy electric field, the nearly low temperature environment of being convenient to about 50 degrees centigrade is plasma state, can greatly strengthen sterilization effect.
The present invention is compounded in ozone and hydrogen peroxide low-temperature plasma in the equipment, will look after two kinds of disinfection way to the demand of environment.Ozone has requirement to humidity, temperature, concentration, and hydrogen peroxide low-temperature plasma is to having requirement to cabin body vacuum.In order to satisfy the demands, reduce the volume of instrument, the sterilizing cabin body is welded after anti-oxidant treatment by aluminium sheet.
As shown in Figure 2, a kind of method for disinfection and sterilization that adopts Fig. 1 device comprises the steps:
(1) in the body of cabin, puts into the article that are sterilized, device is powered up startup;
(2) select the sterilization pattern: comprise " the compound hydrogen peroxide of low-temperature plasma ", " ozone " two kinds of patterns, wherein,
A, when selecting " the compound hydrogen peroxide of low-temperature plasma " sterilization pattern, the cabin body is by the Resistant heating in the outside, when temperature reached 47-56 ℃, electromagnetic valve 14 was opened, and was bled about 5 minutes by vacuum pump 13, and the cabin bromhidrosis is forced down in 2000 handkerchiefs; At this moment, electromagnetic valve 14 cuts out, and electromagnetic valve 8 is opened, and by shut electromagnetic valve 3 behind 4 milliliters of hydrogen peroxide of peristaltic pump injection, nebulizes in 5 minutes in cabin internal diffusion condensation; Again open electromagnetic valve 14, shut electromagnetic valve 14 when the startup vacuum pump is evacuated to the 39-45 handkerchief, electromagnetic valve 8 is opened and is repeated to inject 2.5 milliliters of hydrogen peroxide, then shut electromagnetic valve 8, open electromagnetic valve 14 and continue evacuation, by the pressure transducer 12 real-time pressure that detect in the body of cabin, make it maintain the 80-200 handkerchief, load high-voltage pulse (approximately 3000 volt) to electrode plate with high voltage this moment, the hydrogen peroxide of disperse is under the excitation of high electric field in the body of cabin, be provoked into plasma state, make plasma act on uniformly apparatus, moment punctures at a high speed, etching, protein and nucleic acid substances in the microorganism of oxidation apparatus surface attachment make its deactivation reach the sterilization purpose, and sterilization effect is strengthened greatly.After sterilization was finished, hydrogen peroxide plasma finally was combined into a small amount of steam, and unharmful substance is residual, and is harmless, pollution-free to medical personnel.
B, when selecting " ozone " disinfection way, by the temperature in the temperature sensor 6 detection cabins that are installed in the body of cabin, when temperature is higher than 25 ℃, instrument can not start, continuation is in room temperature state borehole cooling (to solve the heat impact of process of plasma ion disinfection mode), in case the decomposition of ozone in hot environment.When temperature is lower than 25 ℃, system start-up, the humidity that humidity sensor 4 detects in the body of cabin, when humidity less than 80% the time, ultrasonic humidifier 1 work, electromagnetic valve 3 is opened, steam enters humidification in the cabin, when humidity is higher than 80%, source of oxygen (oxygen cylinder 10 is supplied with) is produced the ozone of high concentration by ozonator 9 (higfh-tension ceramics generation), electromagnetic valve 7 is opened (all electromagnetic valves are normally closed solenoid valve), and ozone enters in the body of cabin (concentration is higher than 40mg/L), carries out the disperse sterilization.This ozonization pattern can the Real-Time Monitoring temperature, humidity and ozone concentration, and is pollution-free after sterilization is finished, noresidue.
Adopt the index contrast of apparatus of the present invention and method and prior art to list in table 1.
Table 1
Figure BDA0000100472900000051

Claims (4)

1. the method for a sterilization adopts with lower device and realizes, this device comprises the cabin body, source of oxygen, peristaltic pump, ultrasonic humidifier and vacuum pump, and body top, described cabin is provided with temperature sensor, ozone concentration sensor and humidity sensor; Body bottom, cabin is provided with baroceptor; Described source of oxygen by ozonator within the 4th electromagnetic valve leads to the cabin body; Described ultrasonic humidifier is within the second electromagnetic valve leads to the cabin body; The external side in cabin is provided with the heating element heater that can heat the cabin body; Described peristaltic pump one end is communicated with H 2O 2, the other end is in the 3rd electromagnetic valve passes into the cabin body; The opposed electrode plate with high voltage that is equipped with in body inwall both sides, cabin, described vacuum pump connects through the first electromagnetic valve and cabin bulk phase, it is characterized in that, and method for disinfection and sterilization comprises the steps:
(1) in the body of cabin, puts into the article that are sterilized, device is powered up startup;
(2) select the sterilization pattern: in " the compound hydrogen peroxide of low-temperature plasma " and " ozone " two kinds of patterns, select one, wherein,
A, when selecting " the compound hydrogen peroxide of low-temperature plasma " sterilization pattern, the cabin body is heated by heating, to 47-56 ℃, open the first electromagnetic valve, by the vacuum pump evacuation, the cabin bromhidrosis is forced down behind 2000 handkerchiefs the first closed electromagnetic valve, open the 3rd electromagnetic valve, by closing the 3rd electromagnetic valve behind 4 milliliters of hydrogen peroxide of peristaltic pump injection, make hydrogen peroxide be condensed into vaporific at the cabin internal diffusion; Secondary is opened the first electromagnetic valve, start and close the first electromagnetic valve when vacuum pump is evacuated to the 39-45 handkerchief, secondary is opened the 3rd electromagnetic valve and is repeated to inject hydrogen peroxide less than the injection rate first time, then close the 3rd electromagnetic valve, again open the first electromagnetic valve and continue evacuation, detect in real time pressure in the body of cabin by pressure transducer, make it maintain the 80-200 handkerchief, load high-voltage pulse to electrode plate with high voltage this moment, the hydrogen peroxide of disperse is under the excitation of high electric field in the body of cabin, be provoked into plasma state, act on uniformly the article that are sterilized;
B, when selecting " ozone " disinfection way, detect temperature in the cabin by temperature sensor, when temperature is lower than 25 ℃, humidity sensor detects the humidity in the body of cabin, when humidity less than 80% the time, ultrasonic humidifier starts, the second electromagnetic valve is opened, steam enters humidification in the cabin, when humidity was higher than 80%, source of oxygen produced ozone by ozonator, and the 4th electromagnetic valve is opened, ozone enters in the body of cabin, carries out the disperse sterilization.
2. the method for sterilization as claimed in claim 1 is characterized in that, the described high-voltage pulse that electrode plate with high voltage is loaded is 3000 volts.
3. the method for sterilization as claimed in claim 1 is characterized in that, the ozone that described ozonator produces, and its concentration is higher than 40mg/L.
4. the method for sterilization as claimed in claim 1 is characterized in that, the amount of injecting hydrogen peroxide the described second time is 2.5 milliliters.
CN 201110318295 2011-10-20 2011-10-20 Composite disinfecting and sterilizing device and method Expired - Fee Related CN102363045B (en)

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