CN205982087U - Based on fluorescence detection FDM system - Google Patents

Based on fluorescence detection FDM system Download PDF

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Publication number
CN205982087U
CN205982087U CN201620772773.6U CN201620772773U CN205982087U CN 205982087 U CN205982087 U CN 205982087U CN 201620772773 U CN201620772773 U CN 201620772773U CN 205982087 U CN205982087 U CN 205982087U
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China
Prior art keywords
fluorescence
filter plate
plate group
power detector
utility
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Expired - Fee Related
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CN201620772773.6U
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Chinese (zh)
Inventor
李劲东
陈小颖
王贵源
万戈江
杨旭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guizhou Biological Technology Co Ltd
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Guizhou Biological Technology Co Ltd
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Priority to CN201620772773.6U priority Critical patent/CN205982087U/en
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Abstract

The utility model discloses a based on fluorescence detection FDM system, this FDM system include filter plate group (8), fluorescence light path (9) and luminous power detector APD (10), (8) the parallel arrangement of filter plate group has the multi -disc, and laser lamp -house (1) radiation beam produces fluorescence (4) on glass window (2) is used in the sample, and scioptics (5) focus on fluorescence (4) to filter plate group (8), organizes the filter effects of (8) through the filter plate, shine to luminous power detector APD (10) fluorescence (4) of different passageways, luminous power detector APD (10) connects on computer (7). The utility model discloses can realize in real time, clearly acquireing more the fluorescence signal's function.

Description

One kind is based on fluoroscopic examination FDM system
Technical field
This utility model is related to technical field of fluorescence detection, specially a kind of FDM system based on fluoroscopic examination.
Background technology
At present, that market is used for fluoroscopic examination is CCD.CCD device and its application technology are mainly used in being in image Sensing and non-cpntact measurement field, can accurately be measured to testee, be analyzed.CCD to act like film the same, but It is that optical signal is converted into charge signal.The photodiode of many marshallings is had on CCD, light can be sensed, and by light Signal is transformed into the signal of telecommunication, amplifies through external sampling and analog to digital conversion circuit is converted into data image signal.So in fluorescence inspection Survey aspect, CCD does spectrum analyses and the differentiation aspect of fluorescence signal still plays than larger effect.Although CCD has performance Stable, pattern distortion is little, no image retention the advantages of, but there are two kinds of deficiencies on the fluoroscopic examination of gene analysiss:It is first The spectrum analyses of CCD are by the dispersion of grating various fluoroscopic examinations out, technically more complicated;Secondly, it is subject to It is limited to the signal fluorescence cross that the dispersion of grating detects serious, lead to information to be lost, cause missing inspection and wrong report simultaneously.
Utility model content
For problem above, this utility model provides one kind and is based on fluoroscopic examination FDM system, can be with effectively solving background Problem in technology.
For achieving the above object, this utility model provides following technical scheme:A kind of FDM system based on fluoroscopic examination, This FDM system includes filter plate group, fluorescence light path and optical power detector APD, and described filter plate group is arranged with multi-disc in parallel, and It is provided with lens, the surface of described lens is provided with windowpane, is provided with laser light directly over described windowpane directly over filter plate group Source, capillary tube passes through windowpane, and described LASER Light Source transmitting light acts on sample through windowpane, by the convergence of lens Effect is radiated on dispersing prism, and fluorescence dispersion irradiation is focused to filter plate group by dispersing prism, then reflects parallel fluorescent Light path is connected on computer to optical power detector APD, described optical power detector APD.
Compared with prior art, the beneficial effects of the utility model are:
(1) this utility model is directed to the research needs of gene analysiss fluoroscopic examination, with reference to existing CCD technology, based on light Many laser of communication and FDM treatment technology, devise that a kind of structure is simple, are easy to make, signal sensitivity is high, can be to fluorescence Detect the signal of different center frequency, and mid frequency section is narrow, can effectively reduce the FDM system of fluorescence cross phenomenon System.
(2) FDM system of the present utility model, through system combination, by the data analysiss of each light path out, can obtain The details of more fluorescence is it is seen that the optical signal that more branches away.
(3) this utility model adopts sensitivity higher, and speed faster optical power detector APD substitutes CCD, uses optical filter Group replaces grating, makes the selection of wavelength of fluorescence more flexible, solves the problems, such as fluorescence cross simultaneously, can obtain more fluorescence letters Breath, this FDM system is with practical value to the detection of public security legal medical expert, hospital laboratory and judicial expertise mechanism and research.
Brief description
Fig. 1 is this utility model structural representation
In figure:1- LASER Light Source;2- windowpane;3- capillary tube;4- fluorescence;5- lens;6-FDM;7- computer
Fig. 2 is the FDM system schematic in Fig. 1
8- filter plate group;9- fluorescence light path;10- optical power detector APD
Specific embodiment
Below in conjunction with the accompanying drawing in this utility model embodiment, the technical scheme in this utility model embodiment is carried out Clearly and completely description is it is clear that described embodiment is only a part of embodiment of this utility model rather than whole Embodiment.Based on the embodiment in this utility model, those of ordinary skill in the art are not under the premise of making creative work The every other embodiment being obtained, broadly falls into the scope of this utility model protection.
Embodiment:
Refer to Fig. 1, this utility model provides a kind of technical scheme:One kind is based on fluoroscopic examination FDM system, this FDM system System includes filter plate group, fluorescence light path and optical power detector APD, and described filter plate group is arranged with multi-disc, LASER Light Source in parallel Transmitting light beam acts on generation fluorescence on sample through windowpane, by lens by fluorescent foci to filter plate group, by filtering The filtration of piece group, the fluorescence of different passages is exposed to optical power detector APD, and described optical power detector is connected to meter Calculation machine.
The utility model has the advantage of:
(1) this utility model is directed to the research needs of gene analysiss fluoroscopic examination, with reference to existing CCD technology, based on light Many laser of communication and FDM treatment technology, devise that a kind of structure is simple, are easy to make, signal sensitivity is high, can be to fluorescence Detect the signal of different center frequency, and mid frequency section is narrow, can effectively reduce the FDM system of fluorescence cross phenomenon System.
(2) FDM system of the present utility model, uses the optical filter of deielectric-coating fabrication techniques, chooses through optical filter Required radiation wave band, carries out mid frequency detection, then measures the power of different fluorescence again by optical power detector, then Power signal is sent to data processing end, and the mid frequency of gained and definition all can reach standard.Through system combination, permissible Obtain signal pattern and the analytical data of more fluorescence.
(3) it is the designed reasonability of FDM system of checking and practicality, the system of building is entered experiment and tested, result table The bright acquisition that can successfully obtain more fluorescence signals, be capable of real-time, clear, abundant fluorescence signal details.Originally set The achievement in research of meter is with practical value to the detection of public security legal medical expert, hospital laboratory and judicial expertise mechanism and research.
It should be noted that filter plate group 8, fluorescence light path 9 and optical power detector APD10 belong to FDM system, filter plate Group 8 and optical power detector 10 are realized for the fluorescent screening of required wavelength out individually detecting its power, and are converted into the signal of telecommunication. FDM system mainly using filter plate by the fluorescence of different center frequency, one-level one-level separates, thus realizing separation and the survey of fluorescence Fixed.(Fig. 2)
In addition, FDM system test step:
1. after putting up light path and connect computer;
2. lasing light emitter is irradiated capillary tube specified location;
3. catcher collects fluorescence so that fluorescence irradiates on the collector;
4. the fluorescence that each is separated is calculated mid frequency using optical power detector and records;
5. the data record recording is sent to data analysiss end and is analyzed.
The foregoing is only preferred embodiment of the present utility model, not in order to limit this utility model, all this Any modification, equivalent and improvement made within the spirit of utility model and principle etc., should be included in this utility model Protection domain within.

Claims (1)

1. a kind of fluoroscopic examination FDM system that is based on is it is characterised in that this FDM system includes filter plate group (8), fluorescence light path (9) With optical power detector APD (10), described filter plate group (8) is arranged with multi-disc in parallel, and LASER Light Source (1) transmitting light beam is through glass Glass window (2) acts on and produces fluorescence (4) on sample, by lens (5), fluorescence (4) is focused to filter plate group (8), by filtering The filtration of piece group (8), the fluorescence (4) of different passages is exposed to optical power detector APD (10), described optical power detecting Device APD (10) is connected on computer (7).
CN201620772773.6U 2016-07-21 2016-07-21 Based on fluorescence detection FDM system Expired - Fee Related CN205982087U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620772773.6U CN205982087U (en) 2016-07-21 2016-07-21 Based on fluorescence detection FDM system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620772773.6U CN205982087U (en) 2016-07-21 2016-07-21 Based on fluorescence detection FDM system

Publications (1)

Publication Number Publication Date
CN205982087U true CN205982087U (en) 2017-02-22

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Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106442437A (en) * 2016-07-21 2017-02-22 贵州申科生物科技有限公司 FDM system based on fluorescence detection

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106442437A (en) * 2016-07-21 2017-02-22 贵州申科生物科技有限公司 FDM system based on fluorescence detection

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20170222

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CF01 Termination of patent right due to non-payment of annual fee