CN205974530U - Film filtration sterility testing device - Google Patents
Film filtration sterility testing device Download PDFInfo
- Publication number
- CN205974530U CN205974530U CN201620991651.6U CN201620991651U CN205974530U CN 205974530 U CN205974530 U CN 205974530U CN 201620991651 U CN201620991651 U CN 201620991651U CN 205974530 U CN205974530 U CN 205974530U
- Authority
- CN
- China
- Prior art keywords
- filter cup
- break
- bottle
- test device
- membrane filtration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000001914 filtration Methods 0.000 title abstract description 3
- 238000013190 sterility testing Methods 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 claims abstract description 64
- 230000007246 mechanism Effects 0.000 claims abstract description 25
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 22
- 230000036512 infertility Effects 0.000 claims description 14
- 238000005374 membrane filtration Methods 0.000 claims description 14
- 238000012360 testing method Methods 0.000 claims description 14
- 230000009471 action Effects 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 6
- 230000007306 turnover Effects 0.000 claims description 6
- MGCQZNBCJBRZDT-UHFFFAOYSA-N midodrine hydrochloride Chemical compound [H+].[Cl-].COC1=CC=C(OC)C(C(O)CNC(=O)CN)=C1 MGCQZNBCJBRZDT-UHFFFAOYSA-N 0.000 claims description 2
- 230000000875 corresponding effect Effects 0.000 abstract description 23
- 230000008447 perception Effects 0.000 abstract description 5
- 238000005070 sampling Methods 0.000 abstract description 5
- 230000006872 improvement Effects 0.000 abstract description 2
- 238000005259 measurement Methods 0.000 abstract description 2
- 238000005273 aeration Methods 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 230000001276 controlling effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 206010020852 Hypertonia Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/02—Filters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a film filtration sterility testing device, including the support of fixed appearance bottle, filter cup at least one, appearance liquid pipe, the intraductal appearance liquid of drive appearance liquid carry to filter cup's peristaltic pump from the appearance bottle, as the improvement, every filter cup be equipped with and detect the filter cup liquid level measurement ware, appearance liquid pipe divide the branch liquid pipe that is equipped with with the filter cup one -to -one. Compared with the prior art, the utility model, setting up appearance bottle and falling the caliber of a bottle mechanism, break -make structure, perception filter cup liquid level or / and pressure, through the information that control system gathered the caliber of perception liquid level or pressure, further drive control falls the corresponding action of carrying on of a bottle mechanism, break -make structure, peristaltic pump, has reached the purpose of the aseptic sample of automation. The utility model discloses whole sampling does not need artificial intervention, realizes automaticly, intelligent completely.
Description
Technical field
This utility model is related to a kind of membrane filtration sterility test device.
Background technology
In liquid, content of microorganisms inspection is usually used membrane-filter procedure.Existing device discharge opeing is usually direct discharge opeing,
Pumping equipment structure is simple, and operation all relies on manually, needs substantial amounts of manual operation, and operation repeatability is low, and waste of resource is simultaneously
The service efficiency of lowering apparatus.
Content of the invention
This utility model is to solve the problems, such as prior art in use, provides a kind of structure simple, enables certainly
The membrane filtration sterility test device of dynamic quantitative sampling.
This utility model solve existing issue technical scheme be：A kind of membrane filtration sterility test device, including fixation
The support of sample bottle, filter cup at least one, sample liquid pipe, drive sample liquid in sample liquid pipe to be delivered to the peristaltic pump of filter cup from sample bottle,
As improvement, each described filter cup is provided with detection filter cup liquid level measurer, and described sample liquid pipe is arranged with and filter cup
One-to-one separating tube；Also include the Yang Pingdaoping mechanism being arranged on sample holder；Control the break-make knot that sample liquid Gutron is broken
Structure；Described separating tube sequentially passes through break-make structure, peristaltic pump, and described break-make structure controls the break-make of separating tube one by one,
Gather the information of corresponding filter cup liquid level measurer and control Dao Ping mechanism to turn over bottle, break-make structure closing phase accordingly
Answer separating tube or peristaltic pump action, or bottle turns in Dao Ping mechanism, break-make structure closes corresponding separating tube, peristaltic pump action any
The control system of combination.
As improving further, each described filter cup is additionally provided with the valve of pressometer and control pressure, described
Control system gather corresponding pressometer pressure information, and control valve opens or closes accordingly.
As improving further, described Dao Ping mechanism includes the fixed mount of sample bottle, drives the driver of fixed mount rotation.
As improving further, described fixed mount include the underframe of scalable relative distance with added.
As improving further, described break-make structure includes clamping the jaws of corresponding separating tube and drives corresponding jaws folder
Jaws driver that is tight or unclamping.
As improving further, be provided with described corresponding jaws positioning separating tube passage, passage be provided with hold out against with
Block the push rod of separating tube.
As improving further, also include a liquid level being connected Non-follow control filter cup with control system or/and pressure
Operation button or touch screen.
As improving further, described liquid level measurer is liquid level sensor or weight sensor.
As improving further, described valve is electromagnetic valve；Above-mentioned support is provided with the detection of detection sample bottle empty bottle
Device and alarm.
This utility model compared with prior art, arranges Yang Pingdaoping mechanism, break-make structure, perception filter cup liquid level
Or/and the measuring device of pressure, gather the information of the measuring device of perception liquid level or/and pressure by control system, drive further
Control Dao Ping mechanism, break-make structure, peristaltic pump carry out corresponding action, reached the purpose of automatic sterilized sampling.This reality
It is not required to want manual intervention with new whole sampling, fully achieve automatization, intellectuality.
Brief description
Fig. 1 is structural representation of the present utility model.
Fig. 2 is the structural representation of this utility model pipeline break-make structure.
Fig. 3 is the structural representation of this utility model filter cup.
Fig. 4 is the schematic diagram of this utility model Dao Ping mechanism.
Specific embodiment
Referring to Fig. 1-4, the implementation case includes：The support 1 of fixing sample bottle 4, filter cup 2 at least one, sample liquid pipe 3, drive
In dynamic sample liquid pipe 3, sample liquid is delivered to the peristaltic pump 5 of filter cup 2, the housing 8 of fixing each part from sample bottle 4, and each filter cup 2 sets
There is the measuring device 21 of detection filter cup 2 liquid level or/and pressure, sample liquid pipe 3 is arranged with the one-to-one separating tube 31 with filter cup.
Peristaltic pump 5 and support 1 are arranged on housing 8.
Also include：It is arranged at the Dao Ping mechanism 6 of sample holder 1 loading bottle 4；
Control the break-make structure 7 of sample liquid pipe 3 break-make；Separating tube 31 sequentially passes through break-make structure 7, peristaltic pump 5, break-make structure
7 break-makes controlling separating tube 3 one by one,
Gather the information of corresponding filter cup 2 liquid level measurer 21 and control Dao Ping mechanism 6 to turn over bottle, break-make structure 7 accordingly
Close corresponding separating tube 31 or peristaltic pump 5 action, or bottle turns in Dao Ping mechanism 6, break-make structure 7 closes corresponding separating tube 31,
The control system of the combination in any of peristaltic pump 5 action.
Each filter cup 2 is additionally provided with the valve 22 of pressometer 21 and control pressure, and control system collection is corresponding to press
Force measurement device pressure information, and control valve 22 opens or closes accordingly.Valve 22 is to pass through solenoid-driven, in order to
Control system controls, and the measuring device 21 of pressure and valve 22 can excellent be arranged on the vent line of filter cup 2.
The control system of valve 22 is separately provided, and also can merge the control system of use device, or control system is permissible
Control unit including some independent control corresponding components such as Dao Ping mechanism 6, break-make structure 7, valve 22 or peristaltic pump 5.This reality
Apply in case by merge use device control system carry out as a example.
Dao Ping mechanism 6 includes the fixed mount 61 of sample bottle 4, drives the driver 62 of fixed mount 61 rotation, and driver 62 can be adopted
Use motor.Fixed mount 61 includes the underframe 61a and added 61b of scalable relative distance.In the implementation case underframe 61a with
Added 61b, can be by the slide block adjustable range being arranged on tooth bar 61c, to adapt to corresponding sample bottle 4.Can certainly pass through
Screw rod, nut or slide rail, slide block adjust the distance of underframe 61a and added 61b.
Break-make structure 7 includes the jaws drive clamping the jaws 71 of corresponding separating tube and driving corresponding jaws 71 to clamp or unclamp
Dynamic device, this driver can be preferentially using electromagnetic valve, hydraulic pressure or atmospheric pressure pole.Jaws 71 is provided with the jaws 71 being adapted with separating tube and sets
There is the groove being adapted with separating tube.
It is provided with the passage 72 of positioning separating tube, passage 72 is provided with and holds out against to block the push rod of separating tube in corresponding jaws 71
73, push rod 73 can be directly connected to jaws driver, and groove may be disposed on push rod 73.
For the ease of controlling, also include one and be connected the liquid level of Non-follow control filter cup 2 or/and the behaviour of pressure with control system
Make button or touch screen, it is preferred to use touch screen.
Liquid level measurer is liquid level sensor or weight sensor.Support 1 be provided with detection sample bottle 4 empty bottle detector and
Alarm.
This utility model device use when, the bottleneck of Dao Ping mechanism 6 loading bottle 4 upwards, break-make structure 7 normally opened, as first
Beginning state.When device starts, control system first starts peristaltic pump 5, and then drives Dao Ping mechanism 6 to turn over transfer bottle 4 bottleneck downwards, makes
The valve of filter cup 2 is in aeration status, and in the presence of peristaltic pump 5, sample liquid starts to convey through sample liquid pipe 3, and moistening is filtered
Filter membrane in cup 2, when control system passes through liquid level measurer, after monitoring that the liquid of filter cup 2 reaches moistening preset value, first
Drive Dao Ping mechanism 6 to turn over transfer bottle 4 bottleneck upwards, be then shut off valve 22, discharge the liquid in filter cup 2, work as emptying rate of liquid
Afterwards, control system will open valve 22.Start filtered sample.
During filtered sample, control system first starts peristaltic pump 5, and then drives Dao Ping mechanism 6 to turn over transfer bottle 4 bottleneck downwards,
The valve of filter cup 2 is made to be in aeration status, in the presence of peristaltic pump 5, sample liquid starts conveying sampling through sample liquid pipe 3, from
Corresponding separating tube 31 enters to corresponding filter cup 2.The liquid level sensor of corresponding filter cup 2 or/and weight sensor perception
Sample liquid actual liquid level or weight simultaneously pass to control system, and control system monitors the liquid level that corresponding sample liquid liquid level or weight calculate
Reach preset value, then control corresponding valve 22 to close, increase the pressure in this filter cup 2, make into the sample liquid in filter cup 2
Filtered, valve 22 can control system by the pressure in pressure monitor sensor filter cup 2, if hypertonia after closing
System can close corresponding separating tube by break-make structure 7, and peristaltic pump 5 is slowed or stopped.
If after emptying rate of liquid in sample bottle 4, after detector detects the emptying of sample bottle, alarm changes bottle, and control system will
Order about break-make structure 7 and close separating tube.If do not changed bottle, after emptying rate of liquid in filter cup 2, control system will open valve 22, so
Arresting stop runs afterwards.
After the completion of filtration, can be rinsed, after starter, sample bottle 4 is inverted by control system automatic Dao Ping mechanism 6；Logical
Disconnected structure 7 is normally opened not to work；Control system opens the valve 22 of filter cup 2, and filter cup 2 is in aeration status；When in filter cup 2
Liquid reach a certain amount of after, control system control break-make structure 7 will close this separating tube 31, in three filter cups 2
Liquid measure all reaches same level, and sample bottle 4 is just put, and control system closes the valve 22 of filter cup 2, is filtered, in filter cup 2
After emptying rate of liquid, the valve 22 of opened control system filter bowl 2, then repeats said process again.
If after emptying rate of liquid in sample bottle 4, after detector detects the emptying of sample bottle, alarm changes bottle, and control system will
Order about break-make structure 7 and close separating tube.If do not changed bottle, device stops and records current state.
The leakage fluid dram of filter cup 2 when device carries out fill culture medium, can be closed manually, control system controls break-make structure 7
To opening a separating tube 31, other Close Alls；After starter, control system controls Dao Ping mechanism 6 to be inverted sample bottle 4,
The valve 22 of the filter cup 2 being connected with the separating tube 31 accordingly opened will be opened by control system, and this filter cup 2 is in ventilation shape
State；After being filled filter cup 2 liquid level arrival certain altitude, sample bottle is just put by Dao Ping mechanism 6, and after the several seconds, device is shut down, break-make
Structure 7 is changed and is opened separating tube 31, closes the separating tube 31 closed a dozen and open, and device alarm changes culture medium.（As being set to
Same culture medium, instrument may be configured as multitube fill simultaneously it is also possible to automatic fill one by one in order）.
Claims (10)
1. a kind of membrane filtration sterility test device, including the support of fixing sample bottle, filter cup at least one, sample liquid pipe, driving
In sample liquid pipe sample liquid from sample bottle be delivered to filter cup peristaltic pump it is characterised in that：Each described filter cup is provided with and detected
Filter bowl liquid level measurer, described sample liquid pipe is arranged with the one-to-one separating tube with filter cup；Also include
It is arranged at the Yang Pingdaoping mechanism on sample holder；
Control the break-make structure that sample liquid Gutron is broken；Described separating tube sequentially passes through break-make structure, peristaltic pump, and described break-make is tied
Structure controls the break-make of separating tube one by one,
Gather the information of corresponding filter cup liquid level measurer and control Dao Ping mechanism to turn over corresponding point of bottle, the closing of break-make structure accordingly
Liquid pipe or peristaltic pump action, or bottle turns in Dao Ping mechanism, break-make structure closes corresponding separating tube, the combination in any action of peristaltic pump
Control system.
2. membrane filtration sterility test device as claimed in claim 1 it is characterised in that：Each described filter cup is additionally provided with
Pressometer and the valve of control pressure, described control system gathers corresponding pressometer pressure information, and controls
Valve opens or closes accordingly.
3. membrane filtration sterility test device as claimed in claim 1 it is characterised in that：Described Dao Ping mechanism includes sample bottle
Fixed mount, drive fixed mount rotation driver.
4. membrane filtration sterility test device as claimed in claim 3 it is characterised in that：Described fixed mount includes scalable
The underframe of relative distance with added.
5. membrane filtration sterility test device as claimed in claim 1 it is characterised in that：Described break-make structure includes clamping
The jaws of corresponding separating tube and driving corresponding jaws clamping or the jaws driver unclamped.
6. membrane filtration sterility test device as claimed in claim 5 it is characterised in that：It is fixed to be provided with described corresponding jaws
The passage of position separating tube, passage is provided with and holds out against to block the push rod of separating tube.
7. membrane filtration sterility test device as claimed in claim 1 or 2 it is characterised in that：Also include one and control system
Connect the liquid level of Non-follow control filter cup or/and the operation button of pressure or touch screen.
8. membrane filtration sterility test device as claimed in claim 7 it is characterised in that：Described liquid level measurer is liquid level
Sensor or/and weight sensor.
9. membrane filtration sterility test device as claimed in claim 2 it is characterised in that：Described valve is electromagnetic valve.
10. membrane filtration sterility test device as claimed in claim 1 it is characterised in that：Described support is provided with detection
The detector of sample bottle empty bottle and alarm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620991651.6U CN205974530U (en) | 2016-08-30 | 2016-08-30 | Film filtration sterility testing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620991651.6U CN205974530U (en) | 2016-08-30 | 2016-08-30 | Film filtration sterility testing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205974530U true CN205974530U (en) | 2017-02-22 |
Family
ID=58041309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620991651.6U Expired - Fee Related CN205974530U (en) | 2016-08-30 | 2016-08-30 | Film filtration sterility testing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205974530U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106190810A (en) * | 2016-08-30 | 2016-12-07 | 浙江泰林生物技术股份有限公司 | A kind of membrane filtration sterility test device |
| WO2018153341A1 (en) * | 2017-02-23 | 2018-08-30 | 郑州安图生物工程股份有限公司 | Sample adding system for automatically adding sputum digestion liquid |
-
2016
- 2016-08-30 CN CN201620991651.6U patent/CN205974530U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106190810A (en) * | 2016-08-30 | 2016-12-07 | 浙江泰林生物技术股份有限公司 | A kind of membrane filtration sterility test device |
| WO2018153341A1 (en) * | 2017-02-23 | 2018-08-30 | 郑州安图生物工程股份有限公司 | Sample adding system for automatically adding sputum digestion liquid |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170222 |