CN205528791U - Kit for detecting cell activation antigen - Google Patents
Kit for detecting cell activation antigen Download PDFInfo
- Publication number
- CN205528791U CN205528791U CN201620383443.8U CN201620383443U CN205528791U CN 205528791 U CN205528791 U CN 205528791U CN 201620383443 U CN201620383443 U CN 201620383443U CN 205528791 U CN205528791 U CN 205528791U
- Authority
- CN
- China
- Prior art keywords
- lid
- reagent
- box body
- jack
- cell activation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000427 antigen Substances 0.000 title claims abstract description 14
- 102000036639 antigens Human genes 0.000 title claims abstract description 14
- 108091007433 antigens Proteins 0.000 title claims abstract description 14
- 230000020411 cell activation Effects 0.000 title claims abstract description 11
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 43
- 238000007789 sealing Methods 0.000 claims description 6
- 239000000853 adhesive Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 238000010030 laminating Methods 0.000 claims description 4
- 102000039446 nucleic acids Human genes 0.000 abstract description 6
- 108020004707 nucleic acids Proteins 0.000 abstract description 6
- 150000007523 nucleic acids Chemical class 0.000 abstract description 6
- 238000001514 detection method Methods 0.000 abstract description 4
- 210000004027 cell Anatomy 0.000 description 6
- 210000001744 T-lymphocyte Anatomy 0.000 description 5
- 230000004044 response Effects 0.000 description 4
- 230000001413 cellular effect Effects 0.000 description 3
- 230000003053 immunization Effects 0.000 description 3
- 238000002649 immunization Methods 0.000 description 3
- 230000000890 antigenic effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000003162 effector t lymphocyte Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000684 flow cytometry Methods 0.000 description 2
- 239000007850 fluorescent dye Substances 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 239000002975 chemoattractant Substances 0.000 description 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001215 fluorescent labelling Methods 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000000822 natural killer cell Anatomy 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kit for detecting cell activation antigen, comprises a box bod, the inside of box body is provided with the inside lining, the top of box body is provided with the cover the first lid of inside lining, the surface of inside lining is provided with the jack, the surface of first lid is provided with the correspondence the through -hole of jack the jack fit in has the reagent pipe, be provided with spacing card on the pipe shaft of reagent pipe, the reagent pipe passes that one end department of first lid is provided with the sealed cap, the outside position department of being close to of first lid is provided with the outer lane, the top of first lid is provided with the second lid, this device can detect the nucleic acid or the albumen volume at every different position at the intraductal reagent that adds the difference of reagent, when opening the reagent pipe, can be spacing through first lid, and avoid taking the reagent pipe out when pulling out the sealed cap, provide great facility, make things convenient for going on of detection achievement.
Description
Technical field
This utility model relates to a kind of test kit for detecting cell activation antigen.
Background technology
Cellular immunization broad sense refer to through specific cell (such as cytotoxic T cell) and non-specific cell (as
Macrophage, natural killer cell) immunoreation of increased activity；Narrow sense refers to the immunity that T cell mediates.
Cellular immunization (cellularimmunity) be T cell by after antigenic stimulus, breed, break up, convert
For sensitized T cell (being also effector T cell), when same antigen is again introduced in the cell of body, cause
The cell that direct killing effect and the sensitized T cell of antigen are discharged by quick T cell (effector T cell) because of
The Synergistic killing effect of son, is referred to as cellular immunization.The activation of immunocyte is the one that immunne response produces
Mark.Akinete, after antigenic stimulus activates, shows a series of feature, as surface of cell membrane is lived
The expression etc. of chemoattractant molecule.
The most available flow cytometry, by the characteristic after detection activated immune cell, analyzes antigen-specific
Property immunne response and response rule thereof, and specific cells effect during immunne response can be followed the trail of.
Existing flow cytometry is the instrument of a kind of zero resolution, and it can only measure the such as total nucleic acid of a cell
Amount, the index such as total protein concentration, and can not differentiate and measure the nucleic acid of a certain specific part or albumen number；
According to multiparameter fluorescent labeling, then degradable due to series connection fluorescent dye, the judgement to result can be affected.
Based on the problems referred to above, it is desirable to provide one can carry out classification and Detection according to specific part, meet detection
The test kit needed
Summary of the invention
The technical problems to be solved in the utility model is to provide a kind of reagent for detecting cell activation antigen
Box, this device can add different reagent to detect nucleic acid or the albumen of each different parts in Reagent Tube
Amount, when opening Reagent Tube, can be spacing by the first lid, it is to avoid extract out while pulling out sealing cap
Reagent Tube, it is provided that bigger facility, convenient the carrying out detecting work.
For solving the problems referred to above, this utility model adopts the following technical scheme that
A kind of test kit for detecting cell activation antigen, including box body, being internally provided with of described box body
Liner, described liner extends to the outside of described box body, and the top of described box body is provided with the described liner of covering
The first lid, the surface configuration of described liner has jack, the surface configuration of described first lid to have corresponding institute
Stating the through hole of jack, be combined with Reagent Tube in described jack, described Reagent Tube extends after described through hole
To the top of described first lid, the pipe shaft of described Reagent Tube is provided with spacing card, described spacing card
Offseting with the lower surface of described first lid, described Reagent Tube is arranged through that end of described first lid
There is sealing cap, at the close outer fix of described first lid, be provided with outer ring, the top of described first lid
Being provided with the second lid, the described second described outer ring of lid laminating, between described second lid and described outer ring
Formed and seal.
Preferably, the top of described first lid, the position, outer ring being positioned at described through hole are provided with cannelure,
Reagent number plate it is provided with in described cannelure.
Preferably, the bottom land of described cannelure is provided with Magnetic adhesive mat, and described reagent number plate has magnetic,
Described reagent number plate is attracting with described Magnetic adhesive mat.
Preferably, the outer surface of the described first lid described liner of laminating, described first lid and described box body
Between formed seal.
The beneficial effects of the utility model are: this device can add different reagent in Reagent Tube and detect
The nucleic acid of each different parts or protein content, when opening Reagent Tube, can be spacing by the first lid, keep away
Exempt to extract Reagent Tube out while pulling out sealing cap, it is provided that bigger facility, convenient the carrying out detecting work,
Liner can preferably protect Reagent Tube simultaneously, and the structure of this device is relatively simple, and cost is the cheapest, suitable
Conjunction is promoted the use of.
Accompanying drawing explanation
In order to be illustrated more clearly that this utility model embodiment or technical scheme of the prior art, below by right
In embodiment or description of the prior art, the required accompanying drawing used is briefly described, it should be apparent that below,
Accompanying drawing in description is only embodiments more of the present utility model, for those of ordinary skill in the art,
On the premise of not paying creative work, it is also possible to obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is structural representation of the present utility model.
Detailed description of the invention
Below in conjunction with the accompanying drawings preferred embodiment of the present utility model is described in detail, so that this utility model
Advantage and feature can be easier to be readily appreciated by one skilled in the art, thus to protection domain of the present utility model
Make apparent clear and definite defining.
Refering to a kind of test kit for detecting cell activation antigen shown in Fig. 1, including box body 1, described box
Body 1 be internally provided with liner 2, described liner 2 extends to the outside of described box body 1, described box body 1
Top is provided with the first lid 3 covering described liner 2, and the surface configuration of described liner 2 has jack 201,
The surface configuration of described first lid 3 has the through hole 301 of corresponding described jack 201, in described jack 201
Being combined with Reagent Tube 4, described Reagent Tube 4 extends to the upper of described first lid 3 after described through hole 301
Side, the pipe shaft of described Reagent Tube 4 is provided with spacing card 401, and described spacing card 401 is with described first
The lower surface of lid 3 offsets, and described Reagent Tube 4 is provided with close through that end of described first lid 3
Sealing cap 5, is provided with outer ring 302 at the close outer fix of described first lid 3, described first lid 3
Top is provided with the second lid 6, and described second lid 6 is fitted described outer ring 302, described second lid 6 with
Formed between described outer ring 302 and seal.
A preferred embodiment in this utility model, the top of described first lid 3, is positioned at described through hole
The position, outer ring of 301 is provided with cannelure 311, is provided with reagent number plate in described cannelure 311
312。
A preferred embodiment in this utility model, the bottom land of described cannelure 311 is provided with Magnetic adhesive mat
(not shown), described reagent number plate 312 has magnetic, described reagent number plate 312 and described magnetic sticker
Sheet is attracting.
A preferred embodiment in this utility model, described first lid 3 is fitted the appearance of described liner 2
Face, is formed between described first lid 3 and described box body 1 and seals.
The beneficial effects of the utility model are: this device can add different reagent in Reagent Tube and detect
The nucleic acid of each different parts or protein content, when opening Reagent Tube, can be spacing by the first lid, keep away
Exempt to extract Reagent Tube out while pulling out sealing cap, it is provided that bigger facility, convenient the carrying out detecting work,
Liner can preferably protect Reagent Tube simultaneously, and the structure of this device is relatively simple, and cost is the cheapest, suitable
Conjunction is promoted the use of.
Of the present utility model ultimate principle, principal character and of the present utility model advantage have more than been shown and described.
Skilled person will appreciate that of the industry, this utility model is not restricted to the described embodiments, above-described embodiment
With description described in principle of the present utility model is simply described, without departing from this utility model spirit and model
On the premise of enclosing, this utility model also has various changes and modifications, and these changes and improvements both fall within requirement and protect
In the range of this utility model protected.This utility model claim scope by appending claims and etc.
Jljl is defined.
Claims (4)
1. the test kit being used for detecting cell activation antigen, it is characterised in that: include box body, described box body
Being internally provided with liner, described liner extends to the outside of described box body, and the top of described box body is provided with
Covering the first lid of described liner, the surface configuration of described liner has jack, the table of described first lid
Face is provided with the through hole of corresponding described jack, is combined with Reagent Tube in described jack, and described Reagent Tube is worn
Extend to the top of described first lid after crossing described through hole, the pipe shaft of described Reagent Tube is provided with spacing
Card, described spacing card offsets with the lower surface of described first lid, and described Reagent Tube is through described the
That end of one lid is provided with sealing cap, outside being provided with at the close outer fix of described first lid
Circle, the top of described first lid is provided with the second lid, the described second described outer ring of lid laminating, institute
State to be formed between the second lid and described outer ring and seal.
Test kit for detecting cell activation antigen the most according to claim 1, it is characterised in that: described
The top of the first lid, the position, outer ring being positioned at described through hole are provided with cannelure, at described cannelure
Inside it is provided with reagent number plate.
Test kit for detecting cell activation antigen the most according to claim 2, it is characterised in that: described
The bottom land of cannelure is provided with Magnetic adhesive mat, and described reagent number plate has magnetic, described reagent number plate
Attracting with described Magnetic adhesive mat.
Test kit for detecting cell activation antigen the most according to claim 1, it is characterised in that: described
The outer surface of the first lid described liner of laminating, is formed between described first lid and described box body and seals.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620383443.8U CN205528791U (en) | 2016-04-29 | 2016-04-29 | Kit for detecting cell activation antigen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620383443.8U CN205528791U (en) | 2016-04-29 | 2016-04-29 | Kit for detecting cell activation antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205528791U true CN205528791U (en) | 2016-08-31 |
Family
ID=56794254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620383443.8U Expired - Fee Related CN205528791U (en) | 2016-04-29 | 2016-04-29 | Kit for detecting cell activation antigen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205528791U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109738656A (en) * | 2019-01-29 | 2019-05-10 | 河北艾欧路生物科技有限责任公司 | A kind of cerebrospinal fluid urine total protein assay kit and preparation method of reagent thereof |
| CN113025479A (en) * | 2021-02-28 | 2021-06-25 | 南京帝基生物科技有限公司 | Kit for detecting cell activation antigen |
-
2016
- 2016-04-29 CN CN201620383443.8U patent/CN205528791U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109738656A (en) * | 2019-01-29 | 2019-05-10 | 河北艾欧路生物科技有限责任公司 | A kind of cerebrospinal fluid urine total protein assay kit and preparation method of reagent thereof |
| CN109738656B (en) * | 2019-01-29 | 2022-02-08 | 河北艾欧路生物科技有限责任公司 | Cerebrospinal fluid urine total protein determination kit and reagent preparation method |
| CN113025479A (en) * | 2021-02-28 | 2021-06-25 | 南京帝基生物科技有限公司 | Kit for detecting cell activation antigen |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160831 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |