CN204789588U - Microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected - Google Patents

Microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected Download PDF

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Publication number
CN204789588U
CN204789588U CN201520458429.5U CN201520458429U CN204789588U CN 204789588 U CN204789588 U CN 204789588U CN 201520458429 U CN201520458429 U CN 201520458429U CN 204789588 U CN204789588 U CN 204789588U
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hemolytic anemia
induction type
reagent
gel
micro
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CN201520458429.5U
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周珍祯
陈玉平
刘江敏
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JIANGSU ZHONGJI WANTAI BIOMEDICAL Co Ltd
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JIANGSU ZHONGJI WANTAI BIOMEDICAL Co Ltd
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Abstract

The utility model relates to a microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected, its characterized in that: it includes box body (1), being equipped with microtrabeculae gel card frame (2) and reagent bottleholder (3) in box body (1), wherein having inserted one row of reagent card on microtrabeculae gel card frame (2) side by side, these reagent cards have two kinds of classifications, are first antibiotic class medicine induction type hemolytic anemia detect reagent card (3) and second antibiotic class medicine induction type hemolytic anemia detect reagent card (4) respectively, be equipped with primary antibody release liquid bottle (5), secondary antibody release liquid bottle (6) and third antibody release liquid bottle (7) on reagent bottleholder (3). Reagent is complete among the microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected, and easy operation is convenient, save time, and the testing result is sensitive, can satisfy clinical needs.

Description

The micro-column gel agglutination assay kit that antibiotics induction type hemolytic anemia detects
Technical field
The utility model relates to the micro-column gel agglutination assay kit that a kind of antibiotics induction type hemolytic anemia detects, and for the drug-induced hemolytic anemia of detection of antibiotics class, instructs clinical reasonable selection to use microbiotic.
Background technology
Along with rolling up of types of drugs, especially antibiotics is in clinical a large amount of uses, drug induced hemolytic anemia case is rolled up, red blood cell considerable damage is caused due to immune factor, there is the haemolysis performances such as anaemia, jaundice, color of soy sauce urine clinically, light then affect result for the treatment of, heavy then delay treatment jeopardizes patient vitals's safety.Patient is avoided to cause immune hemolytic anemia because using medicine, just must carry out to patient the detection that immune hemolytic anemia carries out promptly and accurately, stop using the medicine that patient can be made to produce immune hemolytic anemia, instruct and clinically select suitable medicine for patient, improve result for the treatment of.
At present, drug induced hemolytic anemia is detected and is all effectively carried out clinical, its reason is that the detection of drug induced hemolytic anemia belongs to immunohematology sensing range, and immunohematology detection is only carried out at the Blood Transfusion Dept. of clinical hospitals or blood bank, the content that Blood Transfusion Dept. or blood bank check before being only responsible for blood transfusion, all do not carry out drug induced hemolytic anemia testing, therefore can not obtain checkout and diagnosis timely for drug induced patients with hemolytic anemias, cause patient's fatal rate up to more than 30%.
Medicine causes sometimes and is formed the antibody of medicine itself, the drug antibody formed can sensitization or be adsorbed on erythrocyte, cause erythrocyte Direct antiglobulin test positive, erythrocyte is caused to destroy, produce immune hemolysis, patient's hemochrome declines, and result is: the curative effect of medication that 1, treatment patient uses is lowered or suppresses; 2, patient causes anaemia because of drug-induced haemolysis.
In order to avoid because of drug-induced hemolytic anemia, improve the result for the treatment of of medicine, need to carry out Serological testing to drug-induced hemolytic anemia, to determine whether being drug-induced hemolytic anemia, instruct medicine that clinical selecting properly is suitable for the treatment to patient.
Current detection immune hemolytic anemia there is no and detects special kit, and the content detected also only is confined to the unexpected Antibody screening in Direct antiglobulin test, patients blood plasma, judge whether it is immune hemolytic anemia according to the positive or negative of Direct antiglobulin test, the reason that immune hemolytic anemia is classified and caused immune hemolytic anemia can not be detected.
Summary of the invention
The purpose of this utility model is to overcome above-mentioned deficiency, provides the reason accurately can judging immune hemolytic anemia, is applicable to the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection that micro-column gel block-regulations detects.
The purpose of this utility model is achieved in that
The micro-column gel agglutination assay kit that a kind of antibiotics induction type hemolytic anemia detects, it comprises box body, described box body is built with micro-column gel card holder and reagent bottle frame, wherein micro-column gel card holder is inserted with side by side row's reagent card, these reagent cards have two kinds, be respectively the first antibiotics induction type hemolytic anemia and detect reagent card and the second antibiotics induction type hemolytic anemia detection reagent card, described reagent bottle frame is provided with three antibody release liquid bottles, be respectively first antibody release liquid bottle, second antibody release liquid bottle and the 3rd antibody release liquid bottle.
Described first antibiotics induction type hemolytic anemia detects in reagent card and is provided with multiple gel column, is respectively two the first antihuman globulin reagent gel columns, two the second antihuman globulin reagent gel columns and two Blank gel posts.
Described second antibiotics induction type hemolytic anemia detects in reagent card and is provided with multiple gel column, is the 3rd antihuman globulin reagent gel column.
Described first antibiotics induction type hemolytic anemia detects reagent card and the second antibiotics induction type hemolytic anemia detection reagent card is provided with label in the below of gel column.
In described micro-column gel card holder, gel column seals by the top aluminium foil of reagent card.
Top cover is stamped at top in micro-column gel card holder.
Described first antibody release liquid bottle is disodium ethylene diamine tetraacetate antibody release liquid bottle.
Described second antibody release liquid bottle is glycocoll-sodium chloride antibody release liquid bottle.
Described 3rd antibody release liquid bottle is trihydroxy aminomethane-sodium chloride-bromcresol purple antibody release liquid bottle.
The micro-column gel agglutination assay kit that the utility model antibiotics induction type hemolytic anemia detects has the following advantages:
The micro-column gel agglutination assay seminal plasma fructose detection kit that this kind of antibiotics induction type hemolytic anemia detects is complete, simple to operation, save time, testing result is sensitive, can meet clinical needs, whether it not only can detect simultaneously is immune hemolytic anemia, immune hemolytic anemia can also be divided into two classes, i.e. warm autoimmune hemolytic anemia or drug-induced immune hemolytic anemia.
Accompanying drawing explanation
Fig. 1 is the structural representation of the micro-column gel agglutination assay kit that the utility model antibiotics induction type hemolytic anemia detects.
Fig. 2 is the structural representation of micro-column gel card holder in Fig. 1.
Fig. 3 is the front view that in Fig. 2, the first antibiotics induction type hemolytic anemia detects reagent card.
Fig. 4 is the front view that in Fig. 2, the second antibiotics induction type hemolytic anemia detects reagent card.
Fig. 5 is the structural representation of reagent bottle frame in Fig. 1.
In figure: box body 1, micro-column gel card holder 2, reagent bottle frame 3, first antibiotics induction type hemolytic anemia detect reagent card 4, second antibiotics induction type hemolytic anemia and detect reagent card 5, first antibody release liquid bottle 6, second antibody release liquid bottle the 7, the 3rd antibody release liquid bottle 8, top cover 9, label 10, aluminium foil 11.
Embodiment
See Fig. 1 to Fig. 5, the utility model relates to the micro-column gel agglutination assay kit that a kind of antibiotics induction type hemolytic anemia detects, comprise box body 1, described box body 1 is built with micro-column gel card holder 2 and reagent bottle frame 3, micro-column gel card holder 2 and reagent bottle frame 3 are by solid for box body 1, wherein micro-column gel card holder 2 is inserted with side by side row's reagent card, these reagent cards have two kinds, be respectively the first antibiotics induction type hemolytic anemia and detect reagent card 4 and the second antibiotics induction type hemolytic anemia detection reagent card 5, gel column seals with aluminium foil 11 by the top of reagent card, top cover 9 is stamped at the top of micro-column gel card holder 2 simultaneously, reagent card is played a protective role.
Described first antibiotics induction type hemolytic anemia detects in reagent card 4 and is provided with multiple gel column, is respectively two the first antihuman globulin reagent (anti-igg) gel columns, two the second antihuman globulin reagent (anti-C3d) gel columns and two Blank gel posts;
Described second antibiotics induction type hemolytic anemia detects in reagent card 5 and is provided with multiple gel column, is the 3rd antihuman globulin reagent (anti-igg+C3d) gel column;
Described reagent bottle frame 3 is provided with three antibody release liquid bottles, be respectively first antibody release liquid bottle 6, second antibody release liquid bottle 7 and the 3rd antibody release liquid bottle 8, described first antibody release liquid bottle 6 is disodium ethylene diamine tetraacetate antibody release liquid bottle, second antibody release liquid bottle 7 is glycocoll-sodium chloride antibody release liquid bottle, and the 3rd antibody release liquid bottle 8 is trihydroxy aminomethane-sodium chloride-bromcresol purple antibody release liquid bottle.
Described first antibiotics induction type hemolytic anemia detects reagent card 4 and the second antibiotics induction type hemolytic anemia detection reagent card 5 arranges label 10 for identifying corresponding gel column in the below of gel column.
Solution containing 10% disodium ethylene diamine tetraacetate in described first antibody release liquid bottle 6;
Containing the glycocoll of 0.75%, the solution of 0.9% sodium chloride in described first antibody release liquid bottle 7, solution ph is 1.5;
Solution containing 12.1% trihydroxy aminomethane, 5.25% sodium chloride and 0.02% bromcresol purple in described 3rd antibody release liquid bottle 8.

Claims (9)

1. the micro-column gel agglutination assay kit of an antibiotics induction type hemolytic anemia detection, it is characterized in that: it comprises box body (1), described box body (1) is built with micro-column gel card holder (2) and reagent bottle frame (3), wherein micro-column gel card holder (2) is inserted with row's reagent card side by side, these reagent cards have two kinds, be respectively the first antibiotics induction type hemolytic anemia and detect reagent card (4) and the second antibiotics induction type hemolytic anemia detection reagent card (5), described reagent bottle frame (3) is provided with three antibody release liquid bottles, be respectively first antibody release liquid bottle (6), second antibody release liquid bottle (7) and the 3rd antibody release liquid bottle (8).
2. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, it is characterized in that: described first antibiotics induction type hemolytic anemia detects in reagent card (4) and is provided with multiple gel column, is respectively two the first antihuman globulin reagent gel columns, two the second antihuman globulin reagent gel columns and two Blank gel posts.
3. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, it is characterized in that: described second antibiotics induction type hemolytic anemia detects in reagent card (5) and is provided with multiple gel column, is the 3rd antihuman globulin reagent gel column.
4. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: described first antibiotics induction type hemolytic anemia detects reagent card (4) and the second antibiotics induction type hemolytic anemia detection reagent card (5) is provided with label (10) in the below of gel column.
5. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: gel column seals by the top aluminium foil (11) of the upper reagent card of described micro-column gel card holder (2).
6. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: top cover (9) is stamped at the top of micro-column gel card holder (2).
7. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: described first antibody release liquid bottle (6) is disodium ethylene diamine tetraacetate antibody release liquid bottle.
8. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: described second antibody release liquid bottle (7) is glycocoll-sodium chloride antibody release liquid bottle.
9. the micro-column gel agglutination assay kit of a kind of antibiotics induction type hemolytic anemia detection according to claim 1, is characterized in that: described 3rd antibody release liquid bottle (8) is trihydroxy aminomethane-sodium chloride-bromcresol purple antibody release liquid bottle.
CN201520458429.5U 2015-06-30 2015-06-30 Microtrabeculae gel method kit that antibiotic class medicine induction type hemolytic anemia detected Active CN204789588U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107132323A (en) * 2017-07-07 2017-09-05 江苏中济万泰生物医药有限公司 Piperacillin induction hemolysis test kit and preparation method thereof
CN107478852A (en) * 2017-08-31 2017-12-15 张献伟 Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107132323A (en) * 2017-07-07 2017-09-05 江苏中济万泰生物医药有限公司 Piperacillin induction hemolysis test kit and preparation method thereof
CN107478852A (en) * 2017-08-31 2017-12-15 张献伟 Antibiotics induction type hemolytic anemia micro-column gel agglutination assay detection kit

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