CN205479481U - Multichannel valve and chromatographic column - Google Patents
Multichannel valve and chromatographic column Download PDFInfo
- Publication number
- CN205479481U CN205479481U CN201620115870.8U CN201620115870U CN205479481U CN 205479481 U CN205479481 U CN 205479481U CN 201620115870 U CN201620115870 U CN 201620115870U CN 205479481 U CN205479481 U CN 205479481U
- Authority
- CN
- China
- Prior art keywords
- valve
- sieve plate
- chromatographic column
- valve body
- internal cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The utility model provides a multichannel valve, this multichannel valve includes valve body, valve rod, the valve body endotheca is equipped with the endocentric inside and outside cavity that link up from top to bottom, the valve rod is located the internal cavity of valve body, and control opening and shutting of internal cavity. The utility model discloses the chromatographic column including this multichannel valve is still provided. The utility model provides the high cleaning performance of chromatographic column to it is easy and simple to handle.
Description
Technical field
This utility model relates to preparing chromatograph in industry field, specifically, relating to a kind of multiple valve and chromatograph
Post.
Background technology
The main purpose of preparing chromatograph in industry is to obtain pure material from mixture, and current industrial preparative hplc makes
Chromatographic column be typically vertical tubular body.Filler inject solvent and carry out chromatograph and prepare in tubular body.
In existing low-pressure chromatography column purification separates and produces, generally use the chromatographic column of major diameter, low clearance.
The loading of filler of the prior art mainly has a two ways: 1) lid non-central location is opened on a column
Through hole, is pumped into by pipeline or vacuum sucks in chromatographic column；2) in the lower section of capital end sieve plate, vial wall side
Face perforate, is pumped into by pipeline or vacuum sucks in chromatographic column.There is bigger drawback in this kind of mode: 1) top
Perforate will not be opened in middle position in order to avoid the injection of follow-up solvent, so can cause the filler deflection pumped into
While falling, the filling surface after filling has gradient or upper process, eventually affects isolated and purified effect；
2) there is same problem and become apparent from side openings, and the chromatographic column of more major diameter can affect aggravation.
In prior art, the discharge of filler mainly uses two ways: 1) at chromatographic column lower cover (containing sieve plate)
Non-central location opens hole, uses pump or vacuum to suck in chromatographic column by pipeline；2) at post bottom sieve plate
Top, vial wall lateral opening hole, use pump or vacuum to suck in chromatographic column by pipeline.Discharge mode is arranged
There is also the biggest drawback: 1) column jecket side-wall hole, or lower sieve plate perforate can produce certain dead volume, in work
The sample of the filling adsorption remained in cannot well cleaning to hole during skill or impurity, it is impossible to accomplish thoroughly
Cleaning；2) perforate on lower sieve plate, cannot make the eluent on top, hole flow out smoothly at this, can be greatly
Affecting separating effect, product eluting produces conditions of streaking, and yield is substantially reduced, and solvent consumption increases.
Utility model content
In order to overcome above-mentioned technical problem, the purpose of this utility model is to provide a kind of multiple valve, promotes
The cleaning performance of chromatographic column, and easy and simple to handle.
Another object of the present utility model is to provide a kind of chromatographic column including described multiple valve.
To achieve these goals, this utility model provides a kind of multiple valve, including:
Valve body, valve rod；
Being arranged with the inside and outside cavity of concentric up/down perforation in described valve body, described valve rod is located at described valve body
Internal cavity, and control the folding of described internal cavity.
In the optional embodiment of one, the longitudinal profile of the afterbody opening of described internal cavity is inverted trapezoidal.
In the optional embodiment of one, described external cavity is provided with first at the afterbody near described valve body and goes out
Entrance, is provided with the second gateway at the top near valve body.
In the optional embodiment of one, the diameter of described valve body with the ratio of the diameter of described internal cavity is
5:1 to 50:1.
In the optional embodiment of one, the end face of the afterbody opening that described valve rod is positioned at described internal cavity is
Sealing surface.
In the optional embodiment of one, in described sealing surface, sieve plate is set, in described stem internal central authorities
It is communicated with sieve plate the fluid passage of through described valve rod in sealing surface.
In the optional embodiment of one, described valve rod is manual rotation bar, Pneumatic lifting arm or hydraulic pressure liter
Fall bar.
This utility model additionally provides and a kind of includes the chromatographic column of multiple valve described in above-mentioned any one, this color
Spectrum post also includes:
Allotter that post sieve plate connects with external cavity, pressing plate, column jecket；
Described post sieve plate, described allotter and described pressing plate are fitted successively and are arranged in described column jecket, described many
Channel valve is arranged in the small opening of described post sieve plate, described allotter and described pressing plate centre.
In the optional embodiment of one, described post sieve plate includes:
Sieve plate seat, several deck unit；
Described sieve plate seat is provided with that some shapes are identical and the through hole of equidistant distribution, several sieve plate lists described
First and described through hole matches, and is placed in described through hole.
In the optional embodiment of one, the cross section of described deck unit is circle, equilateral triangle, just
Square, regular hexagon or octagon.
Multiple valve described in this utility model embodiment and the chromatographic column of this multiple valve of use, this multichannel
Valve includes valve body and valve rod, is arranged with concentric inside and outside two up/down perforation cavitys in valve body, and valve rod is located at
The internal cavity of valve body, and control the folding of internal cavity.This multiple valve is easy to control, multi-purpose valve, assembling
The chromatographic column having this multiple valve is capable of the outflow of filler and enters while gas, liquid discrepancy chromatographic column
OK, and more preferable to the cleaning performance within chromatographic column.
Accompanying drawing explanation
The structural representation of the multiple valve under the closed mode that Fig. 1 provides for this utility model embodiment；
The structural representation of the multiple valve under the opening that Fig. 2 provides for this utility model embodiment；
The structural representation of the chromatographic column that Fig. 3 provides for this utility model embodiment；
The structural representation of the post sieve plate that Fig. 4 provides for this utility model embodiment；
The structural representation of the multiple valve with fluid passage that Fig. 5 provides for this utility model embodiment.
Detailed description of the invention
Below with reference to the accompanying drawings embodiment of the present utility model is described.At an accompanying drawing of the present utility model or
Plant the element described in embodiment and feature can be shown in one or more other accompanying drawings or embodiment
The element and the feature that go out combine.It should be noted that, for purposes of clarity, accompanying drawing and explanation eliminate with
This utility model unrelated, parts known to persons of ordinary skill in the art or the expression of process and description.
Below in conjunction with the accompanying drawings this utility model is described further.
This utility model embodiment provides a kind of multiple valve, as it is shown in figure 1, this multiple valve 1 includes:
Valve body 11, valve rod 12.
Concentric internal cavity 111 and external cavity 112 it is arranged with in valve body 11.Internal cavity 111 and external cavity 112
It is the structure of up/down perforation.Valve rod 12 is located in the internal cavity 111 of valve body 11, and controls internal cavity 111
Folding.
Concrete, the structure of internal cavity 111 up/down perforation is: internal cavity 111 is at the afterbody 113 of valve body 11
Form afterbody opening 1111, and near the top 114 of valve body 11, offer outlet 1112, thus in being formed
Portion's up/down perforation.
The structure of external cavity 112 up/down perforation is particularly as follows: external cavity 112 is at the afterbody 113 near valve body 11
Position offer the first gateway 1121, offer the second gateway in the position at top 114 near valve body 11
1122, thus form internal up/down perforation.In FIG, 4 to 32 schematically it have been symmetrical arranged uniformly
First gateway 1121 of distribution and two the second gateways 1122, the set-up mode of actual application split shed is also
It is not limited to this.
As it is shown in figure 1, the top 121 of valve rod 12 is through the top 114 of valve body 11, the end of valve rod 12
For end face 122.Preferably, the shape phase of the shape of this end face 122 and the afterbody opening 1111 of valve body 11
Coordinating, the most in FIG, the longitudinal profile of the afterbody opening 1111 of internal cavity 111 can be inverted trapezoidal,
The shape of the longitudinal profile of end face 122 be also inverted trapezoidal and with the longitudinal profile of afterbody opening 1111 to coincideing.
When valve rod 12 moves to the afterbody 113 of valve body 11, end face 122 leaves the afterbody opening of valve body 11
1111, make internal cavity 111 open, as shown in Figure 2.
When valve rod 12 moves to the top 114 of valve body 11, end face 122 returns to the afterbody opening of valve body 11
1111, make internal cavity 111 close, as shown in Figure 1.
Optionally, in this utility model embodiment, the diameter of valve body 11 with the ratio of the diameter of internal cavity 111 is
5:1 to 50:1.
Optionally, valve rod 12 is positioned at the end face 122 of afterbody opening 1111 is sealing surface.This end face 122 4
Week seals, and when preventing internal cavity 111 in off position, in post, liquid enters internal cavity 111 through end face 122, makes
Become to pollute.
Further, as it is shown in figure 5, be provided with sieve plate 1221 in this sealing surface, and inside valve rod 12
Central authorities arrange fluid passage 123, sieve plate 1221 in this communication seals face, fluid passage one end, and run through valve rod
12, the liquid that sieve plate 1221 filters in sealing surface can flow out via fluid passage 123.
Valve rod 12 in this utility model embodiment can be manual rotation bar, Pneumatic lifting arm or hydraulic lifting
Bar.
This utility model embodiment additionally provides a kind of chromatographic column, as it is shown on figure 3, this chromatographic column includes manifold
Road valve 1, post sieve plate 2, allotter 3, pressing plate 4 and column jecket 5.
Wherein the structure of multiple valve 1 refers to the description above of this utility model embodiment, the most superfluous
State.
Post sieve plate 2, allotter 3 and pressing plate 4 are fitted successively and are arranged in column jecket 5, and multiple valve 1 is arranged
In the small opening of post sieve plate 2, allotter 3 and pressing plate 4 centre.
In actual application scenarios, can the column jecket head of chromatographic column and bottom be respectively provided with one group of post sieve plate 2,
Allotter 3, the combination of pressing plate 4.
The post sieve plate 2 of this utility model embodiment includes: sieve plate seat and several deck unit.Wherein sieve plate
Seat is provided with that some shapes are identical and the through hole of equidistant distribution, and several deck unit match with through hole,
It is placed in through hole.Deck unit can use the materials such as nonmetal or metal, and general pore size control is at 1 micron
To 100 microns, this structure can make liquid flow through smoothly.
The sieve plate seat of this utility model embodiment is in the form of annular discs, and the cross section of deck unit is triangle circular, positive
Shape, square, regular hexagon or octagon.Fig. 4 shows shape and the structure of a kind of post sieve plate, sieve
Panel seat 41 is discoid, and the cross section of deck unit 42 is circular.
The deck unit that this utility model embodiment uses, owing to each deck unit diameter is less, therefore resists
Deformability is significantly strengthened, and post sieve plate entirety has more preferable crushing resistance.
Along its center, the most tree-like dissipating arranges some fluid phase partitioning fluid path, each fluid phase on the dispenser
The end of distribution fluid path arranges dispensing orifice, the fluid phase partitioning fluid path at the center of allotter to each dispensing orifice
Length is identical, and the through hole of sieve plate seat is oppositely arranged with dispensing orifice.About the distribution including fluid phase partitioning fluid path
The detailed description of device, refers to ZL200910170013.2 patent, provides a kind of chromatographic column in this patent
Flowing phase partitioning device, this distributor is arranged in tubular body, be equipped with on distributor post sieve
Plate.This distributor can make flowing uniform flow whole post sieve plate with identical speed, makes flowing phase
Distribute uniformly.
As shown in Figures 2 and 3, the external cavity 112 in multiple valve 1 connects with allotter 3, concrete,
Connected with allotter 3 by the first gateway 1121.
With the chromatographic column of multiple valve in this utility model embodiment, liquid enters post Nei Shitong from capital end
Cross the second gateway 1122 and enter gas and liquid, inject through the first gateway 1121 of external cavity 112 and divide
In orchestration 3, liquid is transported to the deck unit central point of correspondence by allotter 3 by fluid phase partitioning fluid path,
Through sub-distribution again, liquid is entered in post by deck unit uniformly；When liquid flows out from post bottom, liquid
Body, after deck unit, is collected to deck unit center by deck unit bottom, by the stream of allotter
Body phase partitioning fluid path is collected to the central area of whole allotter again, flow to outer space by the first gateway 1121
Chamber 112, then flow out outside post through the second gateway 1122.
When moving up valve rod 12, sieve plate sealing surface is opened, and internal cavity 111 is opened, filling out in column jecket 5
Expect that the outlet 1112 from internal cavity 111 is discharged.Owing to chromatographic column is typically relatively large in diameter, and used before
In journey, filler has been compacted, in order to well get rid of filler completely, and can be respectively in the second gateway
1122 are passed through gas and pumping liquid simultaneously breaks up uniform filling jack-up in post, and then flows into internal cavity smoothly
111, flow out through outlet 1112.
When moving down valve rod 12, when internal cavity 111 is closed, sieve plate sealing surface and post sieve plate 2 are one puts down
Face.Now sieve plate sealing surface can pass through liquid, and is flowed out by internal cavity 111.
It is positioned at the pressing plate 4 bottom column jecket 5 to be further secured on blind flange.Blind flange plays support column jecket 5
Effect, bottom column jecket 5, the junction with blind flange is additionally provided with flange.
The multiple valve that this utility model embodiment provides achieves multi-purpose valve, easy and simple to handle, can control
Solid fillers, liquid, gas turnover chromatographic column, and this multiple valve can be contained in chromatographic column stigma or
Person's post tail.When multiple valve is contained in stigma, it is positioned at chromatographic column upper end center position, and the tail of internal cavity
The longitudinal profile of portion's opening is inverted trapezoidal, carries out filler by internal cavity in chromatographic column, and filler can be along inclination
It is settled into a plane under the most therefrom clan of face, will not fall by secundly.When multiple valve is contained in post tail
Time, by internal cavity, filler can be discharged chromatographic column, be typically relatively large in diameter due to chromatographic column and use before
During filler be compacted, in order to well get rid of filler completely, can respectively each second
Gateway is passed through gas and pumping liquid simultaneously and uniform filling jack-up in post is broken up, and then flows into interior empty smoothly
Chamber, flows out through outlet, and cleaning effect is more preferable, and solvent loss is low, and promotes yield.Use this manifold
The chromatographic column of road valve is capable of the outflow of filler and carries out while gas, liquid discrepancy chromatographic column.And
Achieve and multiple valve is installed thus filling out post bottom perimeter big for Area comparison by the small opening of a little area
Material all goes out chromatographic column from multiple valve, and cleaning performance is good.
Although this utility model and advantage thereof have been described in detail it should be appreciated that without departing from by appended
The spirit and scope of the present utility model that limited of claim in the case of can carry out various change, replace
Generation and conversion.And, scope of the present application be not limited only to the process described by description, equipment, means,
The specific embodiment of method and steps.One of ordinary skilled in the art is from disclosure of the present utility model
Will readily appreciate that, execution can be used essentially identical to corresponding embodiment described herein according to this utility model
Function or obtain the result essentially identical with it, the process that existing and future is the most to be developed, equipment,
Means, method or step.Therefore, appended claim is directed in the range of them including such
Process, equipment, means, method or step.
Claims (10)
1. a multiple valve, it is characterised in that including:
Valve body, valve rod；
Being arranged with the inside and outside cavity of concentric up/down perforation in described valve body, described valve rod is located at the internal cavity of described valve body, and controls the folding of described internal cavity.
Multiple valve the most according to claim 1, it is characterised in that the longitudinal profile of the afterbody opening of described internal cavity is inverted trapezoidal.
Multiple valve the most according to claim 1, it is characterised in that described external cavity is provided with the first gateway at the afterbody near described valve body, is provided with the second gateway at the top near valve body.
Multiple valve the most according to claim 1, it is characterised in that the diameter of described valve body is 5:1 to 50:1 with the ratio of the diameter of described internal cavity.
Multiple valve the most according to claim 1, it is characterised in that the end face of the afterbody opening that described valve rod is positioned at described internal cavity is sealing surface.
Multiple valve the most according to claim 5, it is characterised in that in described sealing surface, sieve plate is set, sieve plate the fluid passage of through described valve rod in described stem internal central authorities are communicated with sealing surface.
Multiple valve the most as claimed in any of claims 1 to 6, it is characterised in that described valve rod is manual rotation bar, Pneumatic lifting arm or hydraulic lifting arm.
8. one kind includes the chromatographic column of multiple valve described in any one in claim 1 to 7, it is characterised in that also include:
Allotter that post sieve plate connects with external cavity, pressing plate, column jecket；
Described post sieve plate, described allotter and described pressing plate are fitted successively and are arranged in described column jecket, and described multiple valve is arranged in the small opening of described post sieve plate, described allotter and described pressing plate centre.
Chromatographic column the most according to claim 8, it is characterised in that described post sieve plate includes:
Sieve plate seat, several deck unit；
Described sieve plate seat is provided with that some shapes are identical and the through hole of equidistant distribution, and several deck unit described match with described through hole, are placed in described through hole.
Chromatographic column the most according to claim 9, it is characterised in that the cross section of described deck unit is circle, equilateral triangle, square, regular hexagon or octagon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620115870.8U CN205479481U (en) | 2016-02-05 | 2016-02-05 | Multichannel valve and chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620115870.8U CN205479481U (en) | 2016-02-05 | 2016-02-05 | Multichannel valve and chromatographic column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205479481U true CN205479481U (en) | 2016-08-17 |
Family
ID=56675156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620115870.8U Active CN205479481U (en) | 2016-02-05 | 2016-02-05 | Multichannel valve and chromatographic column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205479481U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107126726A (en) * | 2017-06-30 | 2017-09-05 | 江苏汉邦科技有限公司 | A kind of glue-spraying device |
-
2016
- 2016-02-05 CN CN201620115870.8U patent/CN205479481U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107126726A (en) * | 2017-06-30 | 2017-09-05 | 江苏汉邦科技有限公司 | A kind of glue-spraying device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101972558B (en) | Expanded bed chromatographic separation column used for biochemical separation process and process flow | |
| CN205479481U (en) | Multichannel valve and chromatographic column | |
| CN109517621A (en) | A kind of continous way slurry oil electrostatic separator and separation system and separation method | |
| CN105771354B (en) | One kind printing and dyeing aqueous particulate filter arrangement | |
| CN210543501U (en) | Resin chromatographic column for separating and purifying natural product | |
| CN105570493B (en) | A kind of multiple valve and chromatographic column | |
| DE4211752A1 (en) | Dust filter battery - has adjacent conical inserts to enhance filter efficiency and operational life in continued vertical operation | |
| CN208705286U (en) | A kind of liquid chromatograph and liquid chromatograph enriching column | |
| CN105664526B (en) | A kind of post sieve plate and chromatographic column | |
| CN205550538U (en) | Iron ore sloughing -off tank | |
| CN207520646U (en) | Separation system of simulated moving bed chromatography | |
| CN102078706B (en) | Ion exchange chromatography filtration method and chromatographic separation column thereof | |
| CN207308188U (en) | A kind of liquid-inlet valve | |
| CN204359761U (en) | high performance liquid chromatography ball | |
| CN205435059U (en) | Post sieve and chromatographic column | |
| CN218076501U (en) | Radial and tangential flow bottom for chromatographic column and chromatographic system combined with radial and tangential flow bottom | |
| CN207532865U (en) | Interior cycle continuous sand filter | |
| EP2365860B1 (en) | Pressure swing adsorption system and pressure swing adsorption method | |
| CN205965191U (en) | Three large flow filter that open door | |
| CN220696146U (en) | Trapping system convenient to control liquid level height of trapping device | |
| CN214050540U (en) | Chromatography device | |
| CN205659540U (en) | Fixed adsorption tower of ring type of PSA oxygenerator | |
| CN208130557U (en) | Reinforced chromatographic isolation tower | |
| CN206980149U (en) | A kind of acetic acid rectifying column anti-clogging liquid distribution trough | |
| CN209596875U (en) | A kind of hydrogen chloride and methane chloride separator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A multi-channel valve and chromatographic column Effective date of registration: 20230612 Granted publication date: 20160817 Pledgee: Luanxian Lvhe Agricultural Technology Co.,Ltd. Pledgor: BEIJING CHUANGXIN TONGHENG SCIENCE AND TECHNOLOGY Co.,Ltd. Registration number: Y2023110000228 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right |