A kind of magnetic bionanoparticles kit expressing displaying streptavidin
Technical field
The utility model relates to biological technical field, expresses particularly to one and shows streptavidin
Magnetic bionanoparticles kit.
Background technology
Magnetic separation technique based on magnetic micro-nano granules magnetic bead from the eighties in last century be born with
Come, more and more applied in the field such as life science and clinical detection.Magnetic bead divides
Simple from technical operation, can efficiently, quickly realize separating effect;The manually operated requirement of this technology
Low, also can be applicable to automation equipment operation very well.The magnetic bionanoparticles of Microbe synthesis is
A kind of natural biomagnetism nano material, has incomparable excellent of some Prof. Du Yucang magnetic beads
Gesture.Utilize technique for gene engineering, can show that associated antibodies is many at magnetic bionanoparticles surface orientation
Peptide so that magnetic bionanoparticles is no longer necessary to coupling modified antibodies after preparing, but permissible
It is directly used in the application such as immunity separation.
The nanometer magnetic bead modifying streptavidin has a wide range of applications in scientific research and clinic, needs badly
Develop the kit of maturation, standard, and current already present reagent cartridge configuration is single, behaviour
Make inconvenience.
Utility model content
In order to solve the defect of kit function singleness of the prior art, the utility model provides
One has magnetic bionanoparticles reagent, can be supplied to the use in the field such as related scientific research, detection
Express show streptavidin magnetic bionanoparticles kit.
The concrete technical scheme of the utility model is as follows:
The utility model provides a kind of magnetic bionanoparticles reagent expressed and show streptavidin
Box, including box body and lid, described box body include vertically disposed backboard and with described backboard at the bottom of
The base plate that portion connects, described backboard top is hinged with described lid, and described base plate is provided with and holds
Box, described holding box is arranged over two symmetrically arranged instrument cases, described backboard and described work
Tool box is hinged by runner assembly, and one of them described instrument cases is used for placing magnetic means, separately
Outer described instrument cases are used for placing experiment appliance;
It is provided with liner in described holding box, described liner has in the horizontal direction some for putting
Putting the object placing cavity of reagent bottle, described object placing cavity inner bottom part is provided with compression spring, described object placing cavity top
Portion has stopper slot, places respectively for holding lyophilized biological nano in some described object placing cavities
First reagent bottle of magnetic bead reagent, for hold freeze-dried reagent dilution buffer the second reagent bottle,
For holding the 3rd reagent bottle of lavation buffer solution and for holding the 4th reagent of elution buffer
Bottle.
Further, described runner assembly includes rotating shaft and is set in the first of described rotating shaft two ends
Axle sleeve, described rotating shaft is fixing with the side of described instrument cases to be connected, and the two ends of described rotating shaft are passed through
Described first axle sleeve is hinged with described backboard top, described base plate respectively.
Further, two symmetries it are provided with bottom described instrument cases and between described holding box top
The storage box arranged, described rotating shaft is positioned at cross-under the second axle sleeve bottom described instrument cases, described
Second axle sleeve is fixed on the side of described storage box, and described second axle sleeve and institute are passed through in described rotating shaft
State storage box hinged.
Further, dividing plate it is provided with in one of them described storage box, between adjacent described dividing plate
Form the holding tank for placing teat glass.
Further, on described base plate, arranged on left and right sides is provided with slideway, described Sheng along the longitudinal direction
Putting cassette bottom portion arranged on left and right sides and be provided with the slide plate corresponding with described slideway, described holding box passes through institute
The cooperation stating slide plate and described slideway is slidably connected with described base plate.
Preferably, described lid is provided with some for illuminating and the ultraviolet germicidal lamp of sterilization,
Some described ultraviolet germicidal lamps are and are connected in series.
The beneficial effects of the utility model are as follows: the expression that the utility model provides shows that chain is affine
The magnetic bionanoparticles kit of element is not only simple in structure, and has biology in this kit and receive
Rice magnetic bead reagent, can directly feed the use in the field such as related scientific research, detection, save detection
Time, use convenient, improve detection efficiency, additionally, this kit is possible not only to directly
Tap into row detection test, and reagent storage can be carried out, facilitate reagent bottle to transport.
Accompanying drawing explanation
Fig. 1 is that a kind of expression the described in embodiment 1 shows that the magnetic bionanoparticles of streptavidin tries
The structural representation of agent box;
Fig. 2 is that a kind of expression the described in embodiment 1 shows that the magnetic bionanoparticles of streptavidin tries
The front view of holding box in agent box;
Fig. 3 is that a kind of expression the described in embodiment 2 shows that the magnetic bionanoparticles of streptavidin tries
The structure chart of instrument cases in agent box;
Fig. 4 is that a kind of expression the described in embodiment 2 shows that the magnetic bionanoparticles of streptavidin tries
The structural representation one of agent box;
Fig. 5 is that a kind of expression the described in embodiment 2 shows that the magnetic bionanoparticles of streptavidin tries
The structure chart of storage box in agent box;
Fig. 6 is that a kind of expression the described in embodiment 2 shows that the magnetic bionanoparticles of streptavidin tries
Holding box and the annexation figure of base plate in agent box;
Fig. 7 is that a kind of expression the described in embodiment 2 shows that the magnetic bionanoparticles of streptavidin tries
The structural representation two of agent box.
Wherein: 1, lid;2, backboard;3, base plate;4, holding box;5, instrument cases;6、
Runner assembly;7, magnetic means;8, liner;9, object placing cavity;10, compression spring;11、
Stopper slot;12, the first reagent bottle;13, the second reagent bottle;14, the 3rd reagent bottle;15、
4th reagent bottle;16, rotating shaft;17, the first axle sleeve;18, storage box;19, the second axle sleeve;
20, dividing plate;21, holding tank;22, slideway;23, slide plate;24, ultraviolet germicidal lamp.
Detailed description of the invention
With following example, the utility model is described in further detail below in conjunction with the accompanying drawings.
Embodiment 1
As it is shown in figure 1, the utility model embodiment 1 provides a kind of expression shows streptavidin
Magnetic bionanoparticles kit, including box body and lid 1, described box body includes vertically disposed
Backboard 2 and with the base plate 3 being connected bottom described backboard 2, described backboard 2 top and described lid
1 is hinged, and described base plate 3 is provided with holding box 4, and described holding box 4 is arranged over two symmetries
The instrument cases 5 arranged, described backboard 2 is hinged by runner assembly 6 with described instrument cases 5, its
In described instrument cases 5 be used for placing magnetic means 7, described in another one, instrument cases 5 are used for
Place experiment appliance.
As in figure 2 it is shown, be provided with liner 8 in described holding box 4, along level side on described liner 8
To having some object placing cavities 9 for placing reagent bottle, described object placing cavity 9 inner bottom part is provided with compression
Spring 10, described object placing cavity 9 top has stopper slot 11, in some described object placing cavities 9 respectively
Place the first reagent bottle 12 for holding lyophilized magnetic bionanoparticles reagent, freeze for holding
Second reagent bottle 13 of dry reagent dilutions buffer solution, for holding the 3rd reagent of lavation buffer solution
Bottle 14 and for holding the 4th reagent bottle 15 of elution buffer.
Reagent bottle is connected in object placing cavity 9 by compression spring 10, and reagent bottle cap is connected to spacing
In groove 11, prevent reagent bottle from mutually colliding in transportation, improve reagent bottle and transporting
Security in journey.
Embodiment 2
The utility model embodiment 2 provides a kind of biological nano magnetic expressed and show streptavidin
Pearl kit, this embodiment 2 further defines the knot of kit on the basis of embodiment 1
Structure.
As it is shown on figure 3, the technical program further defines the structure of runner assembly 6, from
And achieve instrument cases 5 and rotate relative to backboard 2, described runner assembly 6 includes rotating shaft 16 He
It is set in first axle sleeve 17 at described rotating shaft 16 two ends, described rotating shaft 16 and described instrument cases 5
Side fixing connect, the two ends of described rotating shaft 16 by described first axle sleeve 17 respectively with institute
State backboard 2 top, described base plate 3 hinged, by rotating shaft 16 and axle sleeve, make instrument cases 5 with
Backboard 2 is rotationally connected, easy to use, simple to operate.
As shown in Figures 4 and 5, need to further describe, bottom described instrument cases 5 and institute
Stating and be provided with two symmetrically arranged storage boxes 18 between holding box 4 top, described rotating shaft 16 is upper
Cross-under the second axle sleeve 19 bottom described instrument cases 5, described second axle sleeve 19 be fixed on described in deposit
The side of storage box 18, described rotating shaft 16 is by described second axle sleeve 19 and described storage box 18
Hinged.Storage box 18 is hinged with described rotating shaft 16 by the second axle sleeve 19, the second axle sleeve 19
Noose is in rotating shaft 16, thus realizes storage box 18 and rotate relative to backboard 2, storage box 18
Inside it is possible to prevent teat glass, container or standby magnetic means 7 etc..
It is to be understood that be provided with dividing plate 20 in one of them described storage box 18, adjacent described
The holding tank 21 for placing teat glass is formed between dividing plate 20.Can be by by dividing plate 20
Separate into some intervals, different interval interior placement teat glasses in storage box 18, prevent test tube from existing
Damaged in collision in transportation.
As shown in Figure 6, taking reagent bottle for convenience, the utility model defines described base plate 3
Upper arranged on left and right sides is provided with slideway 22, arranged on left and right sides bottom described holding box 4 along the longitudinal direction
Being provided with the slide plate 23 corresponding with described slideway 22, described holding box 4 is by described slide plate 23 He
The cooperation of described slideway 22 is slidably connected with described base plate 3.Holding box 4 slides even with base plate 3
Connecing, can directly pull open holding box 4 and take reagent bottle, this holding box 4 is similar to that drawer,
Easy to use, simple to operate.
As shown in Figure 7, it is preferred that described lid 1 be provided with some for illumination and sterilization
Ultraviolet germicidal lamp 24, some described ultraviolet germicidal lamps 24 are and are connected in series.By using
Ultraviolet germicidal lamp 24, the storage for reagent provides safe storage environment, prevents reagent from handing over
Fork infects, and improves detection accuracy, practical.
The utility model is not limited to above-mentioned preferred forms, and anyone is of the present utility model
Other various forms of products all can be drawn, no matter but appointing in its shape or structure under enlightenment
What change, every have same as the present application or akin technical scheme, all falls within this practicality
Within novel protection domain.