CN205357946U - Type of facilitating use is lungs save set for lung transplant - Google Patents
Type of facilitating use is lungs save set for lung transplant Download PDFInfo
- Publication number
- CN205357946U CN205357946U CN201620023104.9U CN201620023104U CN205357946U CN 205357946 U CN205357946 U CN 205357946U CN 201620023104 U CN201620023104 U CN 201620023104U CN 205357946 U CN205357946 U CN 205357946U
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- lungs
- casing
- infusion liquid
- box
- described casing
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Abstract
The utility model discloses a type of facilitating use is lungs save set for lung transplant, include: the box, the inner wall of box is provided with the insulating layer, and the roof of box is apron formula structure, and the bottom surface periphery of roof is provided with the sealing washer, and the outer end circumference of roof is provided with a plurality of quick buckles, and the box has the trachea entry, liquid entry, the export of low temperature save liquid, box perfusate entry and the export of box perfusate are preserved to low temperature, is provided with the lungs support in the box, still is provided with the pressure regulation control valve on the box, and the pressure regulation control valve is connected with a pressure adjustment source, the lungs covering membrane of setting in the box, lungs covering membrane have evacuation mouth, lungs import, pulmonary artery perfusate entry and the export of pulmonary vein perfusate, and pulmonary artery perfusate entry and box perfusate entry are connected through the drain pipe through inlet pipe connection, export of pulmonary vein perfusate and the export of box perfusate, the perfusate circulation system of setting outside the box, the oxygen feeding device of setting outside the box.
Description
Technical field
This utility model relates to medical assistance instrument field, particularly to a kind of lung transplantation lungs save set.
Background technology
Lung transplantation be treatment pulmonary disease in whole latter stage (include late period pulmonary parenchyma disease and late period pulmonary vascular disease) unique effectively Therapeutic Method.The donor overwhelming majority used by current lung transplantation is for still to maintain sanguimotor brain death (DBD) donor, and therefore many researcheres have invested sight the research of brain death (DBD) lung transplantation donor.But, there is heart beating donor HBD to there is heartbeat blood supply, spinning without mandrel NHBD is then contrary, and acardia blood supply exists Warm ischemia injury in various degree, As time goes on and gradually loses function, is not suitable for carrying out lung transplant again.Warm ischemia injury time length determines the quality for lung quality, carries out the cooling of lungs as early as possible, and shortening heat Ischemia Time is the requisite measure that lungs preserve, and low temperature can reduce cellular metabolism, enzymatic activity and energy consumption, slows down cell death, is the important measures preserving internal organs.
After donor opens breast taking-up lungs, lungs carry out fast cooling via pulmonary artery perfusion low temperature lung preserving liquid, appropriateness is filled with oxygen, oxygen containing lung can retain a part of aerobic metabolism, making ATP avoid exhausting, swelling state contributes to the fluid transport function of the lung integrity at cooling jet flow stage reservation alveolar surface material and epithelium in addition.Toronto lung transplantation center is recommended, and being under end tidal gas amount state for lung, maintains the PIP of maximum 15-20cmH2O, obtains and preserves for lung.This is the classical mode of current manure patterns.But the preserving type of this classics, transport in distance, or highlands, or would be likely to occur relatively low atmospheric pressure in flight (aircraft in the aerial cabin of height pressure lower than ground normal atmosphere (An)), the pressure differential that can produce due to pressure change, if periphery atmospheric pressure rapid drawdown, can cause for Hyperinflation, now for the inhomogeneity of atelectasis, produce mechanical stress and shearing force, Alveolar capillary permeability can be increased, increase the weight of lung gas leakage, pulmonary edema and inflammatory reaction, cause mechanicalness injury of lung, cause for lung impaired, affect the success of lung transplant and the late result of patient.Therefore, the transhipment for lung is very restricted, and causes that remote districts donor can not make full use of, forms the waste of medical treatment.
Although, have at present Chinese patent Authorization Notice No. CN102960335B (authorized announcement date 2013.12.25) disclose a kind of be applied in spinning without mandrel lung transplantation lungs low temperature, the device of sequential preservation of ventilating, but this device cannot solve equally distance transport highlands or during shipping due to injury of lung problem that change of atmospheric pressure causes.
Utility model content
The purpose of this utility model is in that the above-mentioned deficiency for prior art and defect, thering is provided a kind of ready-to-use type lung transplantation lungs save set, this ready-to-use type lung transplantation lungs save set can overcome the injury of lung problem that the pressure differential produced due to pressure change causes.
This utility model is solved the technical problem that to realize by the following technical solutions:
Ready-to-use type lung transplantation lungs save set, it is characterised in that including:
Casing, the inwall of described casing is provided with thermal insulation layer, the top board of described casing is cover-plate type structure, the periphery, bottom surface of described top board is provided with sealing ring, the outer end of described top board is circumferentially provided with the Rapid fastener that some and described box side coordinates, described casing has air pipe inlet, cryopreservation solution entrance, cryopreservation solution outlet, casing infusion liquid entrance and the outlet of casing infusion liquid, lungs support it is provided with in described casing, described casing is additionally provided with pressure-adjusting control valve, described pressure-adjusting control valve and a pressure and regulates source connection；
It is arranged on the lungs mantle in described casing, described lungs mantle has vacuum orifice, lungs import, pulmonary artery perfusion liquid entrance and the outlet of pulmonary vein infusion liquid, described pulmonary artery perfusion liquid entrance and described casing infusion liquid entrance are connected by feed tube, and the outlet of described pulmonary vein infusion liquid and the outlet of described casing infusion liquid are connected by drain pipe；
Being arranged on the infusion liquid blood circulation outside described casing, the liquid outlet of described infusion liquid blood circulation is connected with described casing infusion liquid entrance, and the liquid return hole of described infusion liquid blood circulation is connected with the outlet of described casing infusion liquid；
It is arranged on the oxygen feedway that described casing is outer and is connected with lungs trachea.
In a preferred embodiment of the present utility model, described infusion liquid blood circulation includes infusion liquid source, circulating pump, chemicals dosing plant, defecator and the display screen being arranged on described box outer surface.
In a preferred embodiment of the present utility model, described infusion liquid blood circulation also includes the detecting device of biochemistry and the electrolyte index detecting in circulation fluid.
In a preferred embodiment of the present utility model, being provided with temperature control system in described casing, described temperature control system includes the temperature sensor, heater and the cooler that are arranged in described casing.
In a preferred embodiment of the present utility model, it is provided with in described feed tube and is connected with described infusion liquid blood circulation and for detecting the first pressure transducer of pulmonary wedge pressure.
In a preferred embodiment of the present utility model, also include one and be arranged on lungs air pipe inlet and the second pressure transducer being connected with described infusion liquid blood circulation.
In a preferred embodiment of the present utility model, the inner surface of described lungs mantle is arranged at intervals with some soft suckers.
In a preferred embodiment of the present utility model, described casing is outside equipped with mechanical traction device, the traction end of described mechanical traction device extends in described casing and is connected with the outer surface of described lungs mantle, described mechanical traction device drives the expansion of described lungs mantle or shrinks, and simulates human body air-breathing and motion of exhaling with this.
In a preferred embodiment of the present utility model, described mechanical traction device includes two traction units being symmetricly set on outside described casing, and each traction unit includes one and extends in described casing and the draw bar that is connected with the outer surface of described lungs mantle and be arranged on described casing driving device in order to drive described draw bar reciprocating outward.
In a preferred embodiment of the present utility model, described driving device is cylinder or linear electric motors.
Owing to have employed technical scheme as above, this utility model can pass through the barometric information in pressure-adjusting control valve regulating box body, when the transport of needs distance or highlands transport or shipping, the barometric information in casing is changed by pressure-adjusting control valve, the pressure inside and outside casing is made to keep consistent, it is to avoid due to the injury of lung problem that pressure differential causes.This utility model can also pass through the activity of lungs mantle and drive lungs movable, carries out air-breathing and motion of exhaling, the passive respiratory of simulation human body, improves lungs activity, reduce the mechanical ventilation injury of lung of lung.
Accompanying drawing explanation
In order to be illustrated more clearly that this utility model embodiment or technical scheme of the prior art, the accompanying drawing used required in embodiment or description of the prior art will be briefly described below, apparently, accompanying drawing in the following describes is only embodiments more of the present utility model, for those of ordinary skill in the art, under the premise not paying creative work, it is also possible to obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is the working state schematic representation of this utility model embodiment 1.
Fig. 2 is the working state schematic representation of this utility model embodiment 2.
Detailed description of the invention
For the technological means making this utility model realize, creation characteristic, reach purpose and effect and be easy to understand, this utility model is further elucidated below.
Embodiment 1
Ready-to-use type lung transplantation lungs save set shown in Figure 1, including casing 100, this casing 100 is transparent cabinet, conveniently observes inner case, and the bottom of casing 100 is provided with several rows travelling wheel 101, is moved easily.The top board of casing 100 is cover-plate type structure, and the periphery, bottom surface of top board is provided with sealing ring, and the outer end of top board is circumferentially provided with some Rapid fasteners coordinated with box side, conveniently operates with.The inwall of casing 100 is provided with thermal insulation layer, convenient and ambient temperature isolation, reduces heat loss.Being provided with air pipe inlet 110, cryopreservation solution entrance 120 and pressure-adjusting control valve 210 on the top board of casing 100, the bottom of casing 100 is provided with cryopreservation solution outlet 130, casing infusion liquid entrance 140 and casing infusion liquid outlet 150.Lungs support (not shown) it is provided with in casing 100.Pressure-adjusting control valve 210 regulates source 220 with a pressure and is connected, it is possible to by pressure-adjusting control valve 210 and pressure regulate source 220 with the use of the pressure condition changed in casing 100.
Lungs mantle 300 it is provided with in casing 100, lungs mantle 300 has vacuum orifice 310, lungs import 320, pulmonary artery perfusion liquid entrance 340 and pulmonary vein infusion liquid outlet 350, lungs import 320 adopts elastic shrinkage mouth structure, and elastic shrinkage mouth structure carries out encapsulation process.Pulmonary artery perfusion liquid entrance 340 and casing infusion liquid entrance 140 are connected by feed tube 10, and pulmonary vein infusion liquid outlet 350 and casing infusion liquid outlet 150 are connected by drain pipe 20.
Being outside equipped with a set of infusion liquid blood circulation 400 at casing 100, the liquid outlet 401 of infusion liquid blood circulation 400 is connected with casing infusion liquid entrance 140, and the liquid return hole 402 of infusion liquid blood circulation 400 exports 150 with casing infusion liquid and is connected.So that infusion liquid blood circulation 400 has multi-functional, infusion liquid blood circulation 400 in the present embodiment includes infusion liquid source 410, circulating pump 420, chemicals dosing plant 430, defecator 440 and the display screen (not shown) being arranged on casing 100 outer surface, and infusion liquid blood circulation 400 also includes the detecting device 450 of biochemistry and the electrolyte index detecting in circulation fluid.
It is additionally provided with outside casing 100 and the lungs trachea 1a oxygen feedway 520 being connected.For the convenient pressure condition detecting lungs trachea 1a, lungs trachea 1a entrance is provided with the pressure transducer 510 that the display screen of the connection with infusion liquid blood circulation 400 connects, and the parameter that this pressure transducer 510 detects may be displayed on display screen.
It is provided with the display screen with infusion liquid blood circulation 400 in feed tube 10 to be connected and for detecting the pressure transducer 11 of pulmonary wedge pressure, tremulous pulse wedge pressure parameter according to display screen display, the gas pressure in the circulating fluid pressure of adjustment infusion liquid blood circulation 400 and casing 100.
In order to the temperature changed in real time in casing 100, temperature control system 600 it is provided with in casing 100, temperature control system 600 includes the temperature sensor 610, heater 620 and the cooler 630 that are arranged in casing 100 so that the temperature in casing 100 can between 0 DEG C～37 DEG C rapid conversion.
Operation principle of the present utility model is as follows:
First lungs 1 are placed in lungs mantle 300 by lungs import 320, so that the outer surface of lungs 1 and lungs mantle 300 can effectively bond when the later stage preserves process, can be placed into again in lungs mantle 300 after outer surface sprayed surface activity bonding material (such as albumin glue) of lungs 1.The inner surface of the lungs mantle 300 in the present embodiment is arranged at intervals with some miniature soft suckers 330, is conveniently adsorbed on further on lungs 1 outer surface.When lungs 1 are intact be placed on lungs mantle 300 after, carry out seal approach, followed by vacuum orifice 310, the space of lungs mantle 300 and lungs 1 carried out evacuation process so that lungs mantle 300 can be bonded on the outer surface of lungs 1.Then can be carried out the steps such as perfusion, immersion, simulated respiration.When needs irrigate, can passing through infusion liquid blood circulation 400 and realize, infusion liquid blood circulation 400 is reclaimed circulation by pulmonary vein 1c after infusion liquid is fed into lungs 1 by the pulmonary artery 1b of lungs 1；When needs soak, add cryopreservation solution by cryopreservation solution entrance 120；When needs simulated respiration, regulate source 220 by pressure-adjusting control valve 210 and pressure and change the pressure between casing 100 and lungs mantle 300 outer surface regularly, make lungs mantle 300 expand or shrink, and then drive lungs 1 to simulate human body air-breathing and motion of exhaling.Of the present utility model it is further advantageous in that, when the transport of needs distance or highlands transport or shipping, when casing 100 periphery air pressure is pressed lower than surface air, regulate source 220 by pressure-adjusting control valve 210 and pressure and change the barometric information in casing 100, the pressure inside and outside casing is made to keep consistent, it is to avoid due to the injury of lung problem that pressure differential causes.
Embodiment 2
Ready-to-use type lung transplantation lungs save set shown in Figure 2, this embodiment is much the same with the structure of embodiment 1 and operation principle, its special feature, the present embodiment is provided with mechanical traction device 500 outer the increasing of casing 100 on the basis of embodiment 1, the traction end of mechanical traction device 500 extends in casing 100 and is connected with the outer surface of lungs mantle 300, mechanical traction device 500 drives lungs mantle 300 to expand or shrink, and simulates human body air-breathing and motion of exhaling with this.Preferred mechanical traction device 500 includes two traction units 510 being symmetricly set on outside casing 100, each traction unit 510 includes one and extends in casing 100 and the draw bar 511 that is connected with the outer surface of lungs mantle 300 and be arranged on casing 100 driving device 512 in order to drive draw bar 511 reciprocating outward, and driving device 512 is cylinder or miniature linear.
Of the present utility model ultimate principle and principal character and of the present utility model advantage have more than been shown and described.Skilled person will appreciate that of the industry; this utility model is not restricted to the described embodiments; described in above-described embodiment and description is that principle of the present utility model is described; under the premise without departing from this utility model spirit and scope; this utility model also has various changes and modifications, and these changes and improvements both fall within the scope of claimed this utility model.This utility model claims scope and is defined by appending claims and equivalent thereof.
Claims (10)
1. ready-to-use type lung transplantation lungs save set, it is characterised in that including:
Casing, the inwall of described casing is provided with thermal insulation layer, the top board of described casing is cover-plate type structure, the periphery, bottom surface of described top board is provided with sealing ring, the outer end of described top board is circumferentially provided with the Rapid fastener that some and described box side coordinates, described casing has air pipe inlet, cryopreservation solution entrance, cryopreservation solution outlet, casing infusion liquid entrance and the outlet of casing infusion liquid, lungs support it is provided with in described casing, described casing is additionally provided with pressure-adjusting control valve, described pressure-adjusting control valve and a pressure and regulates source connection；
It is arranged on the lungs mantle in described casing, described lungs mantle has vacuum orifice, lungs import, pulmonary artery perfusion liquid entrance and the outlet of pulmonary vein infusion liquid, described pulmonary artery perfusion liquid entrance and described casing infusion liquid entrance are connected by feed tube, and the outlet of described pulmonary vein infusion liquid and the outlet of described casing infusion liquid are connected by drain pipe；
Being arranged on the infusion liquid blood circulation outside described casing, the liquid outlet of described infusion liquid blood circulation is connected with described casing infusion liquid entrance, and the liquid return hole of described infusion liquid blood circulation is connected with the outlet of described casing infusion liquid；
It is arranged on the oxygen feedway that described casing is outer and is connected with lungs trachea.
2. ready-to-use type lung transplantation lungs save set as claimed in claim 1, it is characterised in that described infusion liquid blood circulation includes infusion liquid source, circulating pump, chemicals dosing plant, defecator and the display screen being arranged on described box outer surface.
3. ready-to-use type lung transplantation lungs save set as claimed in claim 2, it is characterised in that described infusion liquid blood circulation also includes the detecting device of biochemistry and the electrolyte index detecting in circulation fluid.
4. ready-to-use type lung transplantation lungs save set as claimed in claim 1, it is characterised in that being provided with temperature control system in described casing, described temperature control system includes the temperature sensor, heater and the cooler that are arranged in described casing.
5. ready-to-use type lung transplantation lungs save set as claimed in claim 3, it is characterised in that be provided with in described feed tube and be connected with described infusion liquid blood circulation and for detecting the first pressure transducer of pulmonary wedge pressure.
6. ready-to-use type lung transplantation lungs save set as claimed in claim 3, it is characterised in that also include and be arranged on lungs air pipe inlet and the second pressure transducer being connected with described infusion liquid blood circulation.
7. ready-to-use type lung transplantation lungs save set as claimed in claim 1, it is characterised in that the inner surface of described lungs mantle is arranged at intervals with some soft suckers.
8. ready-to-use type lung transplantation lungs save set as claimed in claim 1, it is characterized in that, described casing is outside equipped with mechanical traction device, the traction end of described mechanical traction device extends in described casing and is connected with the outer surface of described lungs mantle, described mechanical traction device drives the expansion of described lungs mantle or shrinks, and simulates human body air-breathing and motion of exhaling with this.
9. ready-to-use type lung transplantation lungs save set as claimed in claim 8, it is characterized in that, described mechanical traction device includes two traction units being symmetricly set on outside described casing, and each traction unit includes one and extends in described casing and the draw bar that is connected with the outer surface of described lungs mantle and be arranged on described casing driving device in order to drive described draw bar reciprocating outward.
10. ready-to-use type lung transplantation lungs save set as claimed in claim 9, it is characterised in that described driving device is cylinder or linear electric motors.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620023104.9U CN205357946U (en) | 2016-01-11 | 2016-01-11 | Type of facilitating use is lungs save set for lung transplant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620023104.9U CN205357946U (en) | 2016-01-11 | 2016-01-11 | Type of facilitating use is lungs save set for lung transplant |
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| Publication Number | Publication Date |
|---|---|
| CN205357946U true CN205357946U (en) | 2016-07-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620023104.9U Expired - Fee Related CN205357946U (en) | 2016-01-11 | 2016-01-11 | Type of facilitating use is lungs save set for lung transplant |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110199986A (en) * | 2019-06-14 | 2019-09-06 | 吉林大学第一医院 | Lung transplantation lungs save set |
| CN112687144A (en) * | 2020-12-17 | 2021-04-20 | 杭州堃博生物科技有限公司 | Lung supporting device for helping lung contraction and expansion |
| CN112687170A (en) * | 2020-12-17 | 2021-04-20 | 杭州堃博生物科技有限公司 | Multifunctional lung supporting equipment |
| WO2022270165A1 (en) * | 2021-06-22 | 2022-12-29 | 株式会社Ｓｃｒｅｅｎホールディングス | Leak valve and storage container |
-
2016
- 2016-01-11 CN CN201620023104.9U patent/CN205357946U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110199986A (en) * | 2019-06-14 | 2019-09-06 | 吉林大学第一医院 | Lung transplantation lungs save set |
| CN112687144A (en) * | 2020-12-17 | 2021-04-20 | 杭州堃博生物科技有限公司 | Lung supporting device for helping lung contraction and expansion |
| CN112687170A (en) * | 2020-12-17 | 2021-04-20 | 杭州堃博生物科技有限公司 | Multifunctional lung supporting equipment |
| CN112687170B (en) * | 2020-12-17 | 2022-09-27 | 杭州堃博生物科技有限公司 | Multifunctional lung supporting equipment |
| WO2022270165A1 (en) * | 2021-06-22 | 2022-12-29 | 株式会社Ｓｃｒｅｅｎホールディングス | Leak valve and storage container |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160706 Termination date: 20210111 |