CN205182756U - Liquid drop collection device based on micro -fluidic chip - Google Patents
Liquid drop collection device based on micro -fluidic chip Download PDFInfo
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- CN205182756U CN205182756U CN201521034331.3U CN201521034331U CN205182756U CN 205182756 U CN205182756 U CN 205182756U CN 201521034331 U CN201521034331 U CN 201521034331U CN 205182756 U CN205182756 U CN 205182756U
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Abstract
The application discloses liquid drop collection device based on micro -fluidic chip, including the fixed bolster, install liquid drop collector and micro -fluidic chip on the fixed bolster, the drips has been held in the liquid drop collector, micro -fluidic chip has seted up many the communicating pipelines in both ends along vertical direction, the pipeline with drips in the liquid drop collector communicates with each other, micro -fluidic chip is located directly over the liquid drop collector under or. The utility model discloses the device can produce in batches and the precursor liquid drop of high homogeneous fast, chip and drips direct contact, the liquid drop of production have avoided the integration of liquid flow disturbance and liquid drop in directly getting into the drips from the export, solidification module choice UV solidification liquid drop can collected to obtain multi -functional polymer particle. The liquid drop product that liquid drop collection device produced can be used for like nutrition, cosmetics and materials science.
Description
Technical field
The application relates to a kind of droplet collection device based on micro-fluidic chip, and the drop product of generation may be used for as nutrition, cosmetics and material science.
Background technology
Microflow control technique (Microfluidics) is the emerging technology preparing microemulsion, and it is the Science and Technology system being processed or manipulated a small amount of (10-9 to 10-18L) fluid by tens of passage to hundreds of micro-meter scale.By changing the component of oil or the aqueous solution, the microemulsion be widely used in medicine, food, cosmetic field can be prepared, and emulsion is carried out being polymerized just obtain multi-functional polymer particle.
At present, the process that microflow control technique prepares microemulsion first in micro-fluidic chip, produces presoma emulsion droplet, then, drop is entered in receiving liquid by external pipe and collects, and prepares photopolymerisable microemulsion and normally collected by microemulsion in vessel and carry out illumination or directly carry out photopolymerization in pipeline.But, stream of liquid droplets through pipeline time, due to the disturbance of fluid, droplet coalescence phenomenon clearly, has a strong impact on monodispersity and the shape of the drop obtained.In addition, the speed producing drop through said process, compared with slow and amount of droplets is few, is difficult to prepare polymer particle in a large number, limits its application in biomedicine etc.
Utility model content
The purpose of this utility model is to provide a kind of droplet collection device based on micro-fluidic chip, effectively prevent liquid flow disturbance and droplet coalescence.
For achieving the above object, the utility model provides following technical scheme:
The embodiment of the present application discloses a kind of droplet collection device based on micro-fluidic chip, comprise fixed support, described fixed support is provided with drip collector and micro-fluidic chip, collection liquid is contained with in described drip collector, described micro-fluidic chip vertically offers the pipeline that many two ends communicate, collection liquid phase in described pipeline and described drip collector is led to, described micro-fluidic chip to be positioned at directly over described drip collector or immediately below.
Preferably, in above-mentioned droplet collection device, described fixed support comprises base and is fixed on two fixed bars on described base, the first collector holder is fixed with between described two fixed bars, described drip collector and micro-fluidic chip are individually fixed in the two ends of described first collector holder, described first collector holder offer respectively with described micro-fluidic chip pipeline and collect the through hole that liquid is communicated with.
Preferably, in above-mentioned droplet collection device, the liquid feeding end of described micro-fluidic chip is fixed on fixture, described fixture comprises the first cover plate and the second cover plate that are oppositely arranged, elastic washer and conduit is fixed with between described first cover plate and the second cover plate, one end of described conduit to be inserted in described elastic washer and to communicate with the pipeline of described micro-fluidic chip, and the other end of described conduit is connected with fluid injector.
Preferably, in above-mentioned droplet collection device, fixed by screw rod between described fixture and described first collector holder.
Preferably, in above-mentioned droplet collection device, described drip collector is the quartz ampoule communicated up and down.
Preferably, in above-mentioned droplet collection device, the side of described drip collector is placed with uviol lamp.
Preferably, in above-mentioned droplet collection device, described drip collector is positioned at the top of described micro-fluidic chip, and the top of described drip collector is fixed with the second collector holder, and described second collector holder is fixed between described two fixed bars.
Preferably, in above-mentioned droplet collection device, described second collector holder offers the overfall communicated with described drip collector top.
Preferably, in above-mentioned droplet collection device, between the contact surface of described drip collector and the first collector holder, be provided with seal washer.
Compared with prior art, the utility model has the advantage of:
1. collector chips directly contacts with collection liquid, and the drop of generation directly enters from outlet to be collected liquid, avoids liquid flow disturbance and droplet coalescence;
2. volume is little, and quality is light, and portability is strong, be easy to disassembly, cleaning;
3. overflow port and can conveniently take out unnecessary carrier fluid;
4. can observe chip crosspoint and chip edge;
5. can produce batch fast and highly homogeneous presoma drop;
6. UV can be selected to solidify drop at collection curing module, thus obtain multi-functional polymer particle;
Chip in 7 fixtures is connected with quartzy holder by packing ring in groove, and is fixed by standard screws, and by elastic washer, PTFE tube road is directly connected with chip pipeline, dead volume is little;
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present application or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, the accompanying drawing that the following describes is only some embodiments recorded in the application, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Figure 1 shows that the schematic perspective view of droplet collection device in the utility model specific embodiment;
Figure 2 shows that the perspective exploded view of droplet collection device in the utility model specific embodiment.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the utility model embodiment, be described in detail the technical scheme in the utility model embodiment, obviously, described embodiment is only the utility model part embodiment, instead of whole embodiments.Based on the embodiment in the utility model, the every other embodiment that those of ordinary skill in the art obtain under the prerequisite not making creative work, all belongs to the scope of the utility model protection.
Shown in ginseng Fig. 1 and Fig. 2, based on the droplet collection device of micro-fluidic chip, comprise fixed support 1, fixed support 1 is provided with drip collector 2 and micro-fluidic chip 3, collection liquid is contained with in drip collector 2, micro-fluidic chip 3 vertically offers the pipeline that many two ends communicate, and the collection liquid phase in pipeline and drip collector is led to, and micro-fluidic chip 3 is positioned at immediately below drip collector.
In other embodiments, micro-fluidic chip 3 also can be positioned at directly over drip collector.
Fixed support 1 comprises base 101 and is fixed on two fixed bars 102 on base, the first collector holder 103 is fixed with between two fixed bars, drip collector 2 and micro-fluidic chip 3 are individually fixed in the two ends of the first collector holder 103, the first collector holder 103 offer respectively with micro-fluidic chip pipeline and collect the through hole 1031 that liquid is communicated with.
The liquid feeding end of micro-fluidic chip 3 is fixed on fixture 4, fixture 4 comprises the first cover plate 401 and the second cover plate 402 be oppositely arranged, elastic washer 403 and conduit is fixed with between first cover plate 401 and the second cover plate 402, one end of conduit to be inserted in elastic washer 403 and to communicate with the pipeline of micro-fluidic chip 3, and the other end of conduit is connected with fluid injector.
In this technical scheme, micro-fluidic chip is standard chips, and this standard chips is the hard chip that thickness and width are fixed, consistent with fixture inside dimensions, avoids displacement.Chip is fixed by standard M4 screw rod 406 between fixture and the first collector holder.Adjustment packing ring and chip position guarantee that gasket position is connected with the accurate of chip, avoid leakage.
Conduit preferably adopts polytetrafluoro quality of rubber materials, and centre is uniformly distributed four holes, and aperture is slightly less than PTFE catheter outer diameter, hole site and standard chips stream position correspondence.PTFE conduit and polytetrafluoro caoutchouc elasticity packing ring be compact siro spinning technology by the extruding of cover screw.Polytetrafluoro rubber washer overall dimensions is greater than the gasket groove between the first cover plate and the second cover plate, utilizes screw to extrude and produces deformation, realize compact siro spinning technology.PTFE tube head is about 1mm apart from elastic washer exit.
M3 screw 405 by matching between first cover plate 401 and the second cover plate 402 is fixed.
The two ends of the first collector holder 103 are sheathed on two fixed bars respectively, and fix with two hex nuts 1032.
Preferably, drip collector is the quartz ampoule communicated up and down.The side of drip collector is placed with uviol lamp.
Further, the top of drip collector is fixed with the second collector holder 104, second collector holder 104 and is fixed between two fixed bars.Second collector holder offers the overfall 1041 communicated with drip collector top.The two ends of the second collector holder 104 to be sheathed on respectively on two fixed bars and to be fixed by two goat's horn head nuts 1042.
Further, seal washer 1033 is provided with between the contact surface of drip collector and the first collector holder.
Utilize the preparation process of above-mentioned gathering-device batch emulsion:
Drip collector selects hard micro-fluidic chip, under the promotion of micro-injection pump or constant pressure pump, first the immiscible fluid of two-phase produces single emulsion (W1/O in standard chips, or O1/W) or two emulsion, then directly enter under buoyancy and Action of Gravity Field and collect in liquid, define stable liquid stream, create batch fast and the drop of highly homogeneous presoma drop, the monodispersed emulsion droplet diameter range of generation is at 10-250 μm.Collector chips directly contacts with collection liquid, and the drop of generation directly enters from outlet to be collected liquid, avoids liquid flow disturbance and droplet coalescence.
Wherein, the overfall designed in this collector can conveniently pour out current-carrying liquid.Adopt UV to solidify drop, put into uviol lamp in quartz ampoule side, can ultra-violet curing be carried out, with obtained multi-functional polymer particle, thus be applied to nutrition, cosmetics and material science aspect.
It should be noted that, in this article, the such as relational terms of first and second grades and so on is only used for an entity or operation to separate with another entity or operating space, and not necessarily requires or imply the relation that there is any this reality between these entities or operation or sequentially.And, term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thus make to comprise the process of a series of key element, method, article or equipment and not only comprise those key elements, but also comprise other key elements clearly do not listed, or also comprise by the intrinsic key element of this process, method, article or equipment.When not more restrictions, the key element limited by statement " comprising ... ", and be not precluded within process, method, article or the equipment comprising described key element and also there is other identical element.
The above is only the detailed description of the invention of the application; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the application's principle; can also make some improvements and modifications, these improvements and modifications also should be considered as the protection domain of the application.
Claims (9)
1. the droplet collection device based on micro-fluidic chip, it is characterized in that, comprise fixed support, described fixed support is provided with drip collector and micro-fluidic chip, collection liquid is contained with in described drip collector, described micro-fluidic chip vertically offers the pipeline that many two ends communicate, and the collection liquid phase in described pipeline and described drip collector is led to, described micro-fluidic chip to be positioned at directly over described drip collector or immediately below.
2. the droplet collection device based on micro-fluidic chip according to claim 1, it is characterized in that: described fixed support comprises base and is fixed on two fixed bars on described base, the first collector holder is fixed with between described two fixed bars, described drip collector and micro-fluidic chip are individually fixed in the both sides of described first collector holder, described first collector holder offer respectively with described micro-fluidic chip pipeline and collect the through hole that liquid is communicated with.
3. the droplet collection device based on micro-fluidic chip according to claim 2, it is characterized in that: the liquid feeding end of described micro-fluidic chip is fixed on fixture, described fixture comprises the first cover plate and the second cover plate that are oppositely arranged, elastic washer and conduit is fixed with between described first cover plate and the second cover plate, one end of described conduit to be inserted in described elastic washer and to communicate with the pipeline of described micro-fluidic chip, and the other end of described conduit is connected with fluid injector.
4. the droplet collection device based on micro-fluidic chip according to claim 3, is characterized in that: fixed by screw rod between described fixture and described first collector holder.
5. the droplet collection device based on micro-fluidic chip according to claim 1, is characterized in that: described drip collector is the quartz ampoule communicated up and down.
6. the droplet collection device based on micro-fluidic chip according to claim 5, is characterized in that: the side of described drip collector is placed with uviol lamp.
7. the droplet collection device based on micro-fluidic chip according to claim 2, it is characterized in that: described drip collector is positioned at the top of described micro-fluidic chip, the top of described drip collector is fixed with the second collector holder, and described second collector holder is fixed between described two fixed bars.
8. the droplet collection device based on micro-fluidic chip according to claim 7, is characterized in that: described second collector holder offers the overfall communicated with described drip collector top.
9. the droplet collection device based on micro-fluidic chip according to claim 2, is characterized in that: be provided with seal washer between the contact surface of described drip collector and the first collector holder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521034331.3U CN205182756U (en) | 2015-12-14 | 2015-12-14 | Liquid drop collection device based on micro -fluidic chip |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201521034331.3U CN205182756U (en) | 2015-12-14 | 2015-12-14 | Liquid drop collection device based on micro -fluidic chip |
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| CN205182756U true CN205182756U (en) | 2016-04-27 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396632A (en) * | 2015-12-14 | 2016-03-16 | 苏州汶颢芯片科技有限公司 | Liquid drop collection device based on micro-fluidic chip |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396632A (en) * | 2015-12-14 | 2016-03-16 | 苏州汶颢芯片科技有限公司 | Liquid drop collection device based on micro-fluidic chip |
| CN105396632B (en) * | 2015-12-14 | 2017-05-10 | 苏州汶颢芯片科技有限公司 | Liquid drop collection device based on micro-fluidic chip |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | "change of name, title or address" |
Address after: 215000 No. 128, Fang Zhou road, Suzhou Industrial Park, Jiangsu, China Patentee after: SUZHOU WENHAO MICROFLUIDIC TECHNOLOGY Co.,Ltd. Address before: 215808 No. 128, Fang Zhou road, Suzhou Industrial Park, Jiangsu, China Patentee before: SUZHOU WENHAO CHIP TECHNOLOGY Co.,Ltd. |
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| CP03 | "change of name, title or address" |