CN205139156U - Bacillary vaginopathy detector - Google Patents

Bacillary vaginopathy detector Download PDF

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CN205139156U
CN205139156U CN201520925271.8U CN201520925271U CN205139156U CN 205139156 U CN205139156 U CN 205139156U CN 201520925271 U CN201520925271 U CN 201520925271U CN 205139156 U CN205139156 U CN 205139156U
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sample
mechanical arm
microprocessor
axis
gun head
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周宁
李飞
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Guangzhou Jiangyuan Medical Science&technology Co Ltd
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Guangzhou Jiangyuan Medical Science&technology Co Ltd
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Abstract

The utility model discloses a bacillary vaginopathy detector includes safety cover and detector host computer, and this detector host computer includes application of sample device, incubation device and detection device and controlling means, and this application of sample device is used for adding detect reagent for the sample, this incubation device be used for for the sample educate the temperature and this detection device be used for the detection of sample and judge negative and positive nature to reach the function that controlling means is used for controlling application of sample device, incubation device and detection device, based on above -mentioned structure, this bacillary vaginopathy detector will improve the degree of automation of instrument, further improve detection efficiency and accuracy.

Description

Bacterial vaginopathy detecting instrument
Technical field
The utility model relates to medical instruments field, particularly relates to a kind of bacterial vaginopathy detecting instrument.
Background technology
Bacterial vaginosis BV (bacteralvaginosis, BV) be the common a kind of vagina infection diseases of the women of child-bearing age, wherein, Amsel method and Nugent mark as basic methods for clinical diagnosis, with low cost, but by the impact of several factors in practical application, operability is not strong, little in clinical accurate enforcement at present, current clinical conventional test in laboratory method mainly contains clues cell inspection, amine test method, BV fast detection method etc., BV fast detection method is the novel test method promoted with emphasis on current domestic and international market, and the BV detector that existing market occurs is in testing process, operate not up to standardization and automaticity is low, cause detecting and forbidden.
Utility model content
In view of this, be necessary to provide a kind of bacterial vaginopathy detecting instrument to the automaticity of the accuracy and detector that improve testing result in fact.
A kind of bacterial vaginopathy detecting instrument, for detecting sample, described bacterial vaginopathy detecting instrument comprises protective cover and detector main frame, described detector main frame comprises sample adding device, incubation device, pick-up unit, described sample adding device comprises mechanical arm, fixing mechanical arm on the robotic arm, the first drive unit being fixed on the sample loading gun head on described mechanical arm and being connected with described mechanical arm, described sample loading gun head can hold detection reagent, described first drive unit drives described mechanical arm to move to control described sample loading gun head along described mechanical arm to add in described sample by described detection reagent, described incubation device comprises base plate and is fixed on the heating board on described base plate, for giving the insulation of described sample, and described pick-up unit comprises detect aperture position plate, several detect aperture be arranged on the plate of described detect aperture position, be located at the sample cup in described detect aperture and be located at light source and the photoelectric sensor of described detect aperture position plate side, described sample cup is for holding described sample, described photoelectric sensor receives the light that described light source launches and is irradiated to the reflected light after described sample cup, and whether described photoelectric sensor detects and pick out color sample according to described reflected light and infect with judgement sample.
Preferably, described detector main frame also comprises reagent cup, and described reagent cup is for holding described detection reagent, and the described detection reagent in described reagent cup, under the control of described first drive unit, adds in described sample cup by described sample loading gun head.
Preferably, described mechanical arm comprises orthogonal X-axis mechanical arm, Y-axis mechanical arm and Z axis mechanical arm, described first drive unit comprises X-axis driver, Y-axis driver, Z axis driver and syringe pump driver, described X-axis driver is connected with described mechanical arm, to drive described mechanical arm along described X-axis manipulator motion thus to drive described sample loading gun head to move left and right along described X-axis mechanical arm; Described Y-axis driver is connected with described mechanical arm, to drive described mechanical arm along described Y-axis manipulator motion thus to drive described sample loading gun head to move forward and backward along described Y-axis mechanical arm; Described Z axis driver is connected with described mechanical arm, to drive described mechanical arm along described Z axis manipulator motion thus to drive described sample loading gun head to move up and down along described Z axis mechanical arm; Described syringe pump driver is drawn detection reagent for controlling described sample loading gun head and is spued in described sample cup by described detection reagent from described reagent cup.
Preferably, described sample loading gun head is capacitance type structure, and described sample loading gun head can be used for finding out the liquid level in described sample cup.
Preferably, described incubation device also comprises the temp probe be arranged on described heating board, for detecting the temperature of described sample in real time.
Preferably, described pick-up unit also comprises the supporting track detecting driver and be arranged at detect aperture position plate side, described light source and described photoelectric sensor are located at above described supporting track, and described light source and described photoelectric sensor can move along described supporting track under the effect of described detection driver drives.
Preferably, described bacterial vaginopathy detecting instrument also comprises the control device be connected with sample adding device, incubation device, pick-up unit respectively, the driving governor that described control device comprises microprocessor, is connected with microprocessor, described microprocessor controls the operation of described first drive unit and described detection driver by described driving governor.
Preferably, described microprocessor controls by described driving governor light source described in described detection driver drives and described photoelectric sensor to move to the described sample cup holding sample to be detected front end along described supporting track.
Preferably, described control device also comprises the level sensor be connected with microprocessor, when described sample loading gun head is judged by detecting liquid level to leak in described sample and is added detection reagent, leakage is added the Signal transmissions of detection reagent to described microprocessor by described level sensor, and described microprocessor will send prompting alarm command.
Preferably, described control device also comprises the heating controller be connected with microprocessor and the temperature sensor be connected with microprocessor, and described heating controller is for controlling the heating of described heating board; When described sample temperature is lower than preset temperature, described sample temperature is passed to described microprocessor lower than preset temperature signals by described temperature sensor, and described microprocessor controls the heating of described heating board by described heating controller; When described sample temperature is higher than ceiling temperature, described sample temperature is given described microprocessor higher than ceiling temperature signal transmission by described temperature sensor, and described microprocessor controls described heating board by described heating controller and stops heating.
Compared with prior art, above-mentioned bacterial vaginopathy detecting instrument relies on sample adding device, incubation device, pick-up unit and control device to detect, detect the division of labor detailed, control device is relied on to also improve its automaticity, improve the accuracy detected, make operating process more accurate, improve detection efficiency.
Accompanying drawing explanation
Fig. 1 is the structural drawing of bacterial vaginopathy detecting instrument when opening.
Fig. 2 is bacterial vaginopathy detecting instrument vertical view.
Fig. 3 is the vertical view of the primary structure of bacterial vaginopathy detecting instrument.
Fig. 4 is the vertical view of the sample adding device of bacterial vaginopathy detecting instrument
Fig. 5 is the vertical view of the heating plate of bacterial vaginopathy detecting instrument.
Fig. 6 is the rear view of the heating plate of bacterial vaginopathy detecting instrument.
Fig. 7 is the vertical view of the pick-up unit of bacterial vaginopathy detecting instrument.
Fig. 8 is the schematic diagram of the control device of bacterial vaginopathy detecting instrument.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, clear, complete description is carried out to the technical scheme in embodiment.
Please refer to Fig. 1-Fig. 7, a kind of bacterial vaginopathy detecting instrument 100 comprises protective cover 1 and detector main frame 2, and this detector main frame 2 comprises sample adding device 20, incubation device 30 and pick-up unit 40 and control device 50.Sample adding device 20 detects reagent for adding to sample; Incubation device 30 is for educating temperature to sample; Pick-up unit 40 detects for the detection of sample and judges yin and yang attribute; Control device 50 is for controlling the work of sample adding device 20, incubation device 30 and pick-up unit 40.
Please refer to Fig. 2-Fig. 4, sample adding device 20 comprises mechanical arm 28, be fixed on the mechanical arm (not shown) of mechanical arm 28 and the sample loading gun head 25 that is fixed on this mechanical arm and the first drive unit 26 be connected with mechanical arm, and this first drive unit 26 driving device hand runs to drive sample loading gun head 25 to be added in the sample in described pick-up unit 40 by detection reagent along mechanical arm 28.
Mechanical arm 28 wraps the X-axis mechanical arm 81 arranged along X-axis, the Y-axis mechanical arm (not shown) arranged along Y-axis and the Z axis mechanical arm (not shown) arranged along Z axis, first drive unit 26 comprises X-axis driver 23, Y-axis driver 21, Z axis driver 24 and syringe pump driver 22, wherein, X-axis driver 23 is connected with mechanical arm, so that mechanical arm moves along X-axis mechanical arm 81 thus drives sample loading gun head 25 to move left and right along X-axis mechanical arm 81 under X-axis driver 23 acts on, Y-axis driver 21 is connected with mechanical arm, so that mechanical arm drives sample loading gun head 25 to move forward and backward along Y-axis mechanical arm along Y-axis manipulator motion under Y-axis driver 21 acts on, Z axis driver 24 is connected with mechanical arm, so that mechanical arm drives sample loading gun head 25 to move up and down along Z axis mechanical arm along Z axis manipulator motion under Z axis driver 24 acts on, syringe pump driver 22 joins in sample for controlling sample loading gun head 25 absorption detection reagent and being spued by visualizingre agent.In present embodiment, the first drive unit 26 is all preferably motor.
Sample loading gun head 25 is capacitance type structure, and sample loading gun head 25 is for having the silica gel graphite material of electric conductivity, and sample loading gun head 25 can be used for finding out liquid level.Because according to capacitance principle, detection reagent adds to after in sample by sample loading gun head 25, sample liquid level will change, the amount of liquid of sample will change, conductivity also will change thereupon, the detection voltage that condenser type sample loading gun head 25 obtains is also different, therefore by having added detection reagent in the known sample of detection voltage of sample loading gun head 25, therefore when detection reagent does not add in sample by sample loading gun head 25, sample loading gun head 25 also can detect Lou to add state and leaked the information adding detection reagent and pass to control device 50, and send prompting warning by control device 50, thus effectively can prevent leakage to add and detect reagent situation and occur, improve detection accuracy.
Incorporated by reference to referring to Fig. 5 and Fig. 6, incubation device 30 comprises base plate 37, is fixed on the heating board 36 on this base plate 37 and is arranged on several temp probes 38 on heating board 36, incubation device 30 is for giving the insulation of the sample in pick-up unit 40, and temp probe 38 detects the temperature of sample in real time.In present embodiment, preferred incubation device 30 is located at the bottom of pick-up unit 40, and in other embodiments, incubation device 30 can be arranged on other positions around pick-up unit 40, and in addition, Quality control temperature constant is preferably 37 DEG C by present embodiment.
Incorporated by reference to referring to Fig. 7, pick-up unit 40 comprise the strip being arranged on incubation device 30 upper end detect aperture position plate 44, several detect aperture 42 be arranged on detect aperture position plate 44, be located at the sample cup 43 in detect aperture 42 and be located at light source 48 and the photoelectric sensor 45 of detect aperture position plate side, wherein, this sample cup 43 is for holding sample, reflected light after the light that light source 48 is launched is irradiated to sample cup 43 is detected analysis by photoelectric sensor 45, according to the reflective color code technology of cold light source, distinguish that color sample judges yin and yang attribute with this according to this reflected light.Particularly, useful sialidase substrate detects sialidase in vaginal fluid to diagnose BV, because sialidase and sialidase substrate occur to be hydrolyzed the product generated chromogenic reaction can occur in the basic conditions, so add containing after detection agent in the sample to which, the change of color per sample can determine whether to suffer from BV, if blue, green or blue-green is then indicated as the positive and namely infects, and color illustrates that infection is all the more serious more deeply, and the reflective color code technology of cold light source can the color of tracer liquid be blueness, green or blue-green are still yellow, therefore the reflected light be transmitted on sample by detection light source 48 differentiates that adding the color sample after detecting reagent judges whether infected.In present embodiment, preferred light source 48 for the wavelength that emits beam be the monochromatic source of 550nm-610nm.
Pick-up unit 40 also comprises amplifying circuit, reference voltage circuit and A/D convertor circuit, reflected light after the monochromatic light exposure sample cup 43 that light source 48 is launched, finally absorbed by photoelectric sensor 45, after converting voltage to, after amplifying circuit is by voltage amplification to certain multiple, there is provided reference voltage by reference voltage circuit, convert analog voltage to digital signal by A/D convertor circuit.
Pick-up unit 40 also comprises the supporting track 49 detecting driver 41 and be arranged at detect aperture position plate 44 side, light source 48 and photoelectric sensor 45 are located at above supporting track 49, it can move along supporting track 49, when the sample of a detection sample cup 43, light source 48, photoelectric sensor 45 will move to the front end of this sample cup 43 under the driving effect detecting driver 41 along supporting track 49, so that what light source 48 light was concentrated more is mapped on sample cup 43, make testing result more accurate.
This bacterial vaginopathy detecting instrument 100 also comprises reagent cup 6, and reagent cup 6 is arranged on the side of pick-up unit 40, for loading detection reagent.By as follows for the process that detection reagent adds sample to: first, mechanical arm moves along X-axis mechanical arm 81 thus drives sample loading gun head 25 to arrange along X-axis order from left to right under X-axis driver 23 acts on, then mechanical arm drives sample loading gun head 25 to move forward and backward above a reagent cup 6 along Y-axis along Y-axis manipulator motion under the effect of Y-axis driver 21, under the effect of Z axis driver 24, sample loading gun head 25 is driven along Z axis to move up and down to reagent cup 6 detection reagent liquid level along Z axis manipulator motion by mechanical arm again, from and by syringe pump driver 22 control sample loading gun head draw from reagent cup 6 detect reagent, again at Z axis driver 21, Y-axis driver 21 and X-axis driver 24, under syringe pump driver 22 acts on respectively, detection reagent is wherein added in the sample spuing and add sample cup 43 to by sample loading gun head 25.In other embodiments, the sequencing of X-axis driver 23, Y-axis driver 21 and Z axis driver 24 running can change according to actual conditions, does not limit to and present embodiment.
This bacterial vaginopathy detecting instrument 100 also comprises display screen 3 and printer 4; display screen 3 has the location number of yin and yang attribute judged result, detection time, detection date and detection in showing; printer 4 can print above-mentioned information; this printer 4 is provided with overtemperature protection system, can automatically stop printing when printer 4 is overheated.In present embodiment; display screen 3 is touch; user can be arranged this bacterial vaginopathy detecting instrument 100 by touching display screen 3, comprises numbering setting, historical results, print switch, system time, safeguard protection, communication setting, incubative time T, cleaning, debugged program etc.
Please refer to Fig. 8, control device 50 is for controlling the work of sample adding device 20, incubation device 30 and pick-up unit 40.Control device 50 comprises microprocessor (MCU) 501, the driving governor 502 be connected with microprocessor 501, the level sensor 503 that microprocessor 501 connects, the temperature sensor 504 be connected with microprocessor 501, the heating controller 505 be connected with microprocessor 501, the print control unit 506 be connected with microprocessor 501, the touch pad controller 507 be connected with microprocessor 501, the display screen 508 be connected with microprocessor 501 and the hummer 513 be connected with microprocessor 501.
Driving governor 502 is for controlling the operation of the first drive unit 26 and detection driver 41, in present embodiment, driving governor 502 is controlled by the steering order of microprocessor 501 to control X-axis driver 23, Y-axis driver 21, Z axis driver 24, detect the drive actions of driver 41 and syringe pump driver 22, X-axis driver 23 is impelled to drive sample loading gun head 25 to move left and right along X-axis mechanical arm 81, Y-axis driver 21 drives sample loading gun head 25 to move forward and backward along Y-axis mechanical arm, Z axis driver 24 drives sample loading gun head 25 to move up and down along Z axis mechanical arm, the driving of detection driver 41 drives light source 48 and photoelectric sensor 45 to move along supporting track and syringe pump driver 22 drives sample loading gun head 25 to carry out drawing detection reagent and spuing detecting the action of reagent.
Due to sample loading gun head 25 for capacitance type structure can detect the liquid level of sample cup 43, therefore, when sample loading gun head 25 detect leakage add detect reagent time, by level sensor 503 by Signal transmissions to microprocessor 501, microprocessor 501 will send indicating alarm instruction to display screen 508 and hummer 513, so that the information adding and detect reagent is leaked in prompting on display screen 508.
Heating controller 505 works for controlling heating board 36.Heating controller 505 first controls heating board 36 preheating until after arriving 37 degree, place sample, microprocessor 501 generates heat after incubation T time by heating controller 505 subsequently, microprocessor 501 controls the first drive unit 26 by driving governor 502 again and runs, and is added in sample by detection reagent to make sample loading gun head 25.In addition, temperature sensor 504 is also connected with microprocessor 501, and when temperature sensor 504 detects sample temperature lower than preset temperature, microprocessor 501 will control heating board 36 by heating controller 505 and heat; When temperature sensor 504 detects sample temperature higher than higher limit, microprocessor 501 controls heating board 36 by heating controller 505 and stops heating.
Print control unit 506 is for controlling the action of printer 4.
Touch pad controller 507 processes for the operational order of operating personnel on touch pad 514 is transferred to microprocessor 501.
Display screen 508 is controlled by microprocessor 501, so that real-time detection data and testing result show on display screen 508.
The operational amplifier 512 that control device 50 also comprises the RS232 controller 510 be connected with microprocessor 501, the USB controller 511 be connected with microprocessor 501, microprocessor 501 connect.
RS232 controller is for being conveyed through the communication between the external unit of RS232 interface 516 connection and detector; USB controller 511, for being conveyed through the communication between the external unit of USB interface 515 connection and detector, extends detector communication function.
The strong and weak voltage signal changed of reflected light that operational amplifier 512 receives for amplifying photoelectric sensor 45, and be transferred to microprocessor 501.
The testing process of this bacterial vaginopathy detecting instrument 100 is as follows:
Microprocessor 501 first controls heating board 36 preheating by heating controller 505 until put into sample cup 43 again after arriving 37 degree, microprocessor 501 controls heating board 36 according to set incubative time T by heating controller 505 and works after incubation T time subsequently, microprocessor 501 controls the X-axis driver 23 in the first drive unit 26 respectively by driving governor 502 again, Y-axis driver 21, the driving of Z axis driver 24 and syringe pump driver 22, impel mechanical arm to move and drive sample loading gun head 25 to add in the sample in sample cup 43 by the detection reagent in reagent cup, light source 48 and photoelectric sensor 45 are moved to the positive front end of detected sample cup 43 along supporting track 49 by detecting driver 41 by microprocessor 501 again, emission of light is on sample cup, detect complete and analyze after, microprocessor 501 is controlling printer 4 printing test result by print control unit 506, thus realize automatic testing process.
Based on above-mentioned bacterial vaginopathy detecting instrument, overcome existing detector to take up room large defect, and bacterial vaginopathy detecting instrument of the present utility model can realize automatically detecting and automatically showing result, automaticity is high, and in testing process, adopt condenser type sample loading gun head can improve the accuracy of detection, prevent detecting reagent and leak the situation appearance added, improve detection accuracy.
To the above-mentioned explanation of disclosed example, make the art professional can realize or use the utility model.Be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein when not departing from spirit or scope of the present utility model, can realize in other embodiments.Therefore, the utility model can not be restricted to these embodiments shown in this article, but will meet the most wide region consistent with principle disclosed herein and features of novelty.

Claims (10)

1. a bacterial vaginopathy detecting instrument, for detecting sample, described bacterial vaginopathy detecting instrument comprises protective cover and detector main frame, it is characterized in that, described detector main frame comprises sample adding device, incubation device, pick-up unit,
Described sample adding device comprises mechanical arm, fixing mechanical arm on the robotic arm, the first drive unit of being fixed on the sample loading gun head on described mechanical arm and being connected with described mechanical arm, described sample loading gun head can hold detection reagent, and described first drive unit drives described mechanical arm to move to control described sample loading gun head along described mechanical arm to add in described sample by described detection reagent;
Described incubation device comprises base plate and is fixed on the heating board on described base plate, for giving the insulation of described sample; And
Described pick-up unit comprises detect aperture position plate, several detect aperture be arranged on the plate of described detect aperture position, be located at the sample cup in described detect aperture and be located at light source and the photoelectric sensor of described detect aperture position plate side, described sample cup is for holding described sample, described photoelectric sensor receives the light that described light source launches and is irradiated to the reflected light after described sample cup, and whether described photoelectric sensor detects and pick out color sample according to described reflected light and infect with judgement sample.
2. bacterial vaginopathy detecting instrument as claimed in claim 1, it is characterized in that, described detector main frame also comprises reagent cup, described reagent cup is for holding described detection reagent, described detection reagent in described reagent cup, under the control of described first drive unit, adds in described sample cup by described sample loading gun head.
3. bacterial vaginopathy detecting instrument as claimed in claim 2, it is characterized in that, described mechanical arm comprises orthogonal X-axis mechanical arm, Y-axis mechanical arm and Z axis mechanical arm, described first drive unit comprises X-axis driver, Y-axis driver, Z axis driver and syringe pump driver, described X-axis driver is connected with described mechanical arm, to drive described mechanical arm along described X-axis manipulator motion thus to drive described sample loading gun head to move left and right along described X-axis mechanical arm; Described Y-axis driver is connected with described mechanical arm, to drive described mechanical arm along described Y-axis manipulator motion thus to drive described sample loading gun head to move forward and backward along described Y-axis mechanical arm; Described Z axis driver is connected with described mechanical arm, to drive described mechanical arm along described Z axis manipulator motion thus to drive described sample loading gun head to move up and down along described Z axis mechanical arm; Described syringe pump driver is drawn detection reagent for controlling described sample loading gun head and is spued in described sample cup by described detection reagent from described reagent cup.
4. bacterial vaginopathy detecting instrument as claimed in claim 1, it is characterized in that, described sample loading gun head is capacitance type structure, and described sample loading gun head can be used for finding out the liquid level in described sample cup.
5. bacterial vaginopathy detecting instrument as claimed in claim 4, it is characterized in that, described incubation device also comprises the temp probe be arranged on described heating board, for detecting the temperature of described sample in real time.
6. bacterial vaginopathy detecting instrument as claimed in claim 5, it is characterized in that, described pick-up unit also comprises the supporting track detecting driver and be arranged at detect aperture position plate side, described light source and described photoelectric sensor are located at above described supporting track, and described light source and described photoelectric sensor can move along described supporting track under the effect of described detection driver drives.
7. bacterial vaginopathy detecting instrument as claimed in claim 6, it is characterized in that, described bacterial vaginopathy detecting instrument also comprises the control device be connected with sample adding device, incubation device, pick-up unit respectively, the driving governor that described control device comprises microprocessor, is connected with microprocessor, described microprocessor controls the operation of described first drive unit and described detection driver by described driving governor.
8. bacterial vaginopathy detecting instrument as claimed in claim 7, it is characterized in that, described microprocessor controls by described driving governor light source described in described detection driver drives and described photoelectric sensor can move to the described sample cup holding sample to be detected front end along described supporting track.
9. bacterial vaginopathy detecting instrument as claimed in claim 8, it is characterized in that, described control device also comprises the level sensor be connected with microprocessor,
When described sample loading gun head passes through detect liquid level and judge that in described sample, leakage adds detection reagent, leakage is added the Signal transmissions of detection reagent to described microprocessor by described level sensor, and described microprocessor will send prompting alarm command.
10. bacterial vaginopathy detecting instrument as claimed in claim 9, it is characterized in that, described control device also comprises the heating controller be connected with microprocessor and the temperature sensor be connected with microprocessor, and described heating controller is for controlling the heating of described heating board; When described sample temperature is lower than preset temperature, described sample temperature is passed to described microprocessor lower than preset temperature signals by described temperature sensor, and described microprocessor controls the heating of described heating board by described heating controller; When described sample temperature is higher than ceiling temperature, described sample temperature is given described microprocessor higher than ceiling temperature signal transmission by described temperature sensor, and described microprocessor controls described heating board by described heating controller and stops heating.
CN201520925271.8U 2015-11-18 2015-11-18 Bacillary vaginopathy detector Active CN205139156U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105301269A (en) * 2015-11-18 2016-02-03 广州江元医疗科技有限公司 Bacterial vaginosis detector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105301269A (en) * 2015-11-18 2016-02-03 广州江元医疗科技有限公司 Bacterial vaginosis detector

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