CN204939471U - Replacing formula foam collection device - Google Patents

Replacing formula foam collection device Download PDF

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Publication number
CN204939471U
CN204939471U CN201520695540.6U CN201520695540U CN204939471U CN 204939471 U CN204939471 U CN 204939471U CN 201520695540 U CN201520695540 U CN 201520695540U CN 204939471 U CN204939471 U CN 204939471U
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China
Prior art keywords
receiving flask
utility
foam
collection device
reactor
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Application number
CN201520695540.6U
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Chinese (zh)
Inventor
傅晖
岑仡
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Shanghai Sunway Biotech Co Ltd
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Shanghai Sunway Biotech Co Ltd
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Priority to CN201520695540.6U priority Critical patent/CN204939471U/en
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Abstract

The utility model relates to a kind of replacing formula foam collection device, comprise receiving flask, the top of described receiving flask is provided with an inlet mouth and an air outlet, and described air outlet is connected with air strainer, and described inlet mouth is communicated with the venting port of bio-reactor by pipeline.The utility model can effectively eliminate aseptic microorganism reactor cultivate in foam to the detrimentally affect of culture systems, and safety easy to use, with low cost, be applicable to microorganism biological bioreactor culture system.

Description

Replacing formula foam collection device
Technical field
The utility model relates to a kind of foam collection device, is specifically related to a kind of replacing formula foam collection device.
Background technology
In microorganism biological bioreactor culture system, if nutrient solution is rich in protein matter (most of culture system is all like this), in working process under the effect of stirring rake, more foam can be produced, foam is except destroying the cell near liquid level during explosion, the film of bacterium isoreactivity microorganism, wall construction, cause outside microbial death, also can assemble to venting port with tail gas, if do not controlled, it is not smooth that liquid entrained in foam can cause the blocking of venting port hydrophobic air filter to be vented, affect the normal air inlet of inlet end, microorganism growth is caused time serious, metabolic disturbance, until this tank is scrapped (as shown in Figure 1, the exhaust port of bio-reactor 1 is generally connected to air strainer 2, run into foam and water will be blocked).
For eliminating foam to the negative impact of microorganism culturing, usually adopt and tackle in two ways: (1) can add defoamer in part microbial culture system, but about defoamer to the more difficult assessment of negative impact in microorganism (particularly active somatic cell) culturing process; (2) the tank body top of part biological reactor increases a gas inlet and a set of gas flow system, gas flow system is directly controlled by reactor, with the air (or nitrogen) after filtration, cultivation liquid level is given and malleation, object dispels foam, prevent foam from overflowing to exhaust port, but such a process increases equipment cost, and when this venting pressure and foam volume are lacked of proper care, exhaust emissions still may be caused to go out blocking.
Although above two kinds of methods can alleviate foam, reaction system is affected, but still have certain limitation, therefore, to exist the impact of culture systems for foam when how to eliminate bioreactor culture and further improve and optimization demand, this is the power that is accomplished of the utility model and starting point place just.
Utility model content
In order to overcome the above-mentioned technical problem that prior art exists, the present inventor after having carried out a large amount of further investigations, thus completes the utility model.
The utility model is achieved through the following technical solutions, a kind of replacing formula foam collection device, comprise receiving flask, the top of described receiving flask is provided with an inlet mouth and an air outlet, described air outlet is connected with air strainer, and described inlet mouth is communicated with the venting port of bio-reactor by pipeline.
Preferably, the pipeline between described receiving flask with described bio-reactor is provided with and is asepticly connected disconnecting device.
Compared with prior art, the beneficial effects of the utility model are as follows: the utility model effectively eliminate aseptic microorganism reactor cultivate in foam to the detrimentally affect of culture systems, and safety easy to use, with low cost, be applicable to microorganism biological bioreactor culture system.
Accompanying drawing explanation
By reading the detailed description done non-limiting example with reference to the following drawings, other features, objects and advantages of the present utility model will become more obvious:
Fig. 1 is the layout schematic diagram of bio-reactor of the prior art and air strainer.
Fig. 2 is the structural representation of an embodiment of the present utility model.
Embodiment
Below in conjunction with specific embodiment, the utility model is described in detail.Following examples will contribute to those skilled in the art and understand the utility model further, but not limit the utility model in any form.It should be pointed out that to those skilled in the art, without departing from the concept of the premise utility, some distortion and improvement can also be made.These all belong to protection domain of the present utility model.
One as shown in Figure 2 changes formula foam collection device, comprise receiving flask 3, the top of receiving flask 3 is provided with an inlet mouth and an air outlet, air outlet is connected with air strainer 6, air strainer 6 ensures the sterility requirements of system, inlet mouth is communicated with by the venting port of pipeline with bio-reactor 4, the pipeline between receiving flask 3 with bio-reactor 4 is provided with asepticly be connected disconnecting device 5, adds defoamer 7 in receiving flask.
Aseptic connection disconnecting device makes receiving flask can realize aseptic removing and installing, fluid infusion in its mode and culturing process, the pipeline connection disassembling mode of fluid is as good as, when the venting port that the foam in bio-reactor overflows to bio-reactor, be introduced into receiving flask, be stored in receiving flask, because fermentor tank is malleation all the time, defoamer in receiving flask can not pour in down a chimney into culture systems, when after the foam cooling in receiving flask, gas-liquid separation, liquid storage is in receiving flask, gas externally discharges from the air outlet at receiving flask top, because above-mentioned foam collection device can aseptic connection and dismounting, when liquid in receiving flask is full, replaceable another set of foam collection device, so each fermentation system can select the size of foam receiving flask according to the time in respective culturing process between foam volume and order of classes or grades at school.
Above specific embodiment of the utility model is described.It is to be appreciated that the utility model is not limited to above-mentioned particular implementation, those skilled in the art can make various distortion or amendment within the scope of the claims, and this does not affect flesh and blood of the present utility model.

Claims (2)

1. change formula foam collection device for one kind, it is characterized in that, comprise receiving flask, the top of described receiving flask is provided with an inlet mouth and an air outlet, described air outlet is connected with air strainer, and described inlet mouth is communicated with the venting port of bio-reactor by pipeline.
2. a kind of replacing formula foam collection device as claimed in claim 1, is characterized in that, the pipeline between described receiving flask with described bio-reactor is provided with asepticly be connected disconnecting device.
CN201520695540.6U 2015-09-09 2015-09-09 Replacing formula foam collection device Active CN204939471U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520695540.6U CN204939471U (en) 2015-09-09 2015-09-09 Replacing formula foam collection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520695540.6U CN204939471U (en) 2015-09-09 2015-09-09 Replacing formula foam collection device

Publications (1)

Publication Number Publication Date
CN204939471U true CN204939471U (en) 2016-01-06

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201520695540.6U Active CN204939471U (en) 2015-09-09 2015-09-09 Replacing formula foam collection device

Country Status (1)

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CN (1) CN204939471U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961587A (en) * 2020-08-20 2020-11-20 江苏康正生物科技有限公司 Water quality microorganism detection device and detection method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961587A (en) * 2020-08-20 2020-11-20 江苏康正生物科技有限公司 Water quality microorganism detection device and detection method thereof

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