CN204767032U - Flexible neural little electrode array - Google Patents
Flexible neural little electrode array Download PDFInfo
- Publication number
- CN204767032U CN204767032U CN201520407229.7U CN201520407229U CN204767032U CN 204767032 U CN204767032 U CN 204767032U CN 201520407229 U CN201520407229 U CN 201520407229U CN 204767032 U CN204767032 U CN 204767032U
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- Prior art keywords
- flexible
- microelectrode
- insulating barrier
- microelectrode unit
- joint
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- 230000001537 neural effect Effects 0.000 title abstract 3
- 239000000758 substrate Substances 0.000 claims description 47
- 230000004888 barrier function Effects 0.000 claims description 43
- 239000000463 material Substances 0.000 claims description 20
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 9
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 9
- -1 polydimethylsiloxane Polymers 0.000 claims description 9
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 6
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 6
- 229910052804 chromium Inorganic materials 0.000 claims description 6
- 239000011651 chromium Substances 0.000 claims description 6
- 239000010936 titanium Substances 0.000 claims description 6
- 229910052719 titanium Inorganic materials 0.000 claims description 6
- 239000000956 alloy Substances 0.000 claims description 5
- 229910045601 alloy Inorganic materials 0.000 claims description 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical group [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 5
- 239000010931 gold Substances 0.000 claims description 5
- 229910052737 gold Inorganic materials 0.000 claims description 5
- 238000001259 photo etching Methods 0.000 claims description 4
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 abstract 3
- 229910000679 solder Inorganic materials 0.000 abstract 3
- 238000009413 insulation Methods 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 description 11
- 239000002184 metal Substances 0.000 description 11
- 230000005611 electricity Effects 0.000 description 4
- 238000004528 spin coating Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000151 deposition Methods 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002001 electrophysiology Methods 0.000 description 1
- 230000007831 electrophysiology Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001755 magnetron sputter deposition Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Abstract
The utility model relates to a biomedical equipment field especially relates to a flexible neural little electrode array. Flexible neural little electrode array includes flexible basement, insulating layer, microelectrode unit, wire and lead wire solder joint, and microelectrode unit, wire and lead wire solder joint set up in flexible basement, is connected through the wire between microelectrode unit and the lead wire solder joint, and insulation cover is in flexible basement, and the microelectrode unit exposes through exposing in the insulating layer, is equipped with in the flexible basement that a plurality of the microelectrode unit sets up in the hollow form arch of flexible basement through exposing in the hollow forms arch of insulating layer the hollow form arch of insulating layer on be equipped with the adhesion layer, the microelectrode unit set up to be in the adhesion layer on, can effectively reduce the mechanical strength of contact impedance and microelectrode.
Description
Technical field
This utility model relates to biomedical devices field, particularly relates to a kind of flexible nervus array.
Background technology
When carrying out medical diagnosis or corresponding research, need to measure and record the body built-in potential of human body or studied animal, transcutaneous electrostimulation is the means of a kind of aided disease treatment of clinical frequent use in addition.Various Medical measuring instrument device all needs to contact by suitable electrode the transmission realizing the signal of telecommunication with body when carrying out bio electricity and detecting and when applying electricity irritation auxiliary treatment to sick body, when carrying out bio electricity for nerve system of human body and detecting, need to use flexible nervus array, in recent years, owing to there is based on the electrod-array of flexible substrate good bio-compatibility and to organizing less infringement, being widely studied and applied in CO2 laser weld built-in type device.But be generally planar electrode array based on this type of flexible substrate, the flexible micro-electrode of the micro-meter scale of current existence, when not carrying out finishing, there is two problems: 1, the existence of insulating barrier, metal electrode part is caused to be in the state of depression, electrode, along with the reduction of size, is difficult to form good contact with position to be measured; 2, along with the reduction of electrode size, the surface impedance of electrode increases, and Electrophysiology signal is fainter under normal circumstances, and the increase of electrode surface impedance can affect the measurement of signal.
Utility model content
Main purpose of the present utility model is to provide a kind of flexible nervus array that can reduce contact impedance, effectively can improve the contact area of flexible nervus and detected part, reduces the contact impedance of flexible nervus and detected part.
Further, this utility model can also reduce the mechanical strength of microelectrode site, ensure that with detected part good contact while, any damage can not be caused to detected part.
For achieving the above object, this utility model provides a kind of flexible nervus array, comprise flexible substrates, insulating barrier, microelectrode unit, wire and lead solder-joint, described microelectrode unit, wire and lead solder-joint are arranged in described flexible substrates, be connected by described wire between described microelectrode unit and described lead solder-joint, described insulating barrier covers in described flexible substrates, described microelectrode unit exposes to described insulating barrier, described flexible substrates is provided with multiple hollow shape projection exposing to described insulating barrier, the hollow shape projection of described insulating barrier is provided with adhesion layer, described microelectrode unit is arranged on described adhesion layer.
Preferably, described insulating barrier is provided with opening in the position of described lead solder-joint, and described lead solder-joint is exposed by the opening of described insulating barrier.
Preferably, the hollow shape projection of described insulating barrier is provided with adhesion layer, described microelectrode unit is arranged on described adhesion layer.
Preferably, the material of described adhesion layer comprises titanium, chromium, or comprises one or both the alloy in these two kinds of elements, and the material of described microelectrode unit is gold.
Preferably, the material of described flexible substrates comprises polydimethylsiloxane, and the material of described insulating barrier comprises can the polydimethylsiloxane of photoetching.
Preferably, described insulating barrier is made up of multiple lamellar insulant.
A kind of flexible nervus array is provided in this utility model, it comprises flexible substrates, insulating barrier, microelectrode unit, wire and lead solder-joint, microelectrode unit, wire and lead solder-joint are all arranged on a flexible substrate, connected by wire between microelectrode unit and lead solder-joint, insulating barrier covers on a flexible substrate, microelectrode unit exposes to insulating barrier, flexible substrates in this utility model is provided with multiple hollow shape projection exposing to insulating barrier, microelectrode unit is arranged on the adhesion layer in the hollow shape projection of flexible substrates, compared with traditional flexible nervus array, hollow projection in this utility model in flexible substrates arranges microelectrode unit, compared to the flexible substrates microelectrode at plane formula, microelectrode in projection adds the surface area in electricity irritation site, effectively can reduce contact impedance, and because the projection in the flexible substrates in this utility model is hollow, therefore it can reduce the bulk strength of microelectrode site, it is made not easily to cause damage to measured position in use,
This utility model uses the tabular microelectrode with multiple projection to make template when making, spin coating one deck flexible base layer in template is made at microelectrode, route wires and lead solder-joint in flexible base layer afterwards, at the boss deposition microelectrode unit of flexible base layer, and insulating barrier is laid in flexible base layer, and make the microelectrode unit on the boss of flexible base layer and boss expose to insulating barrier, manufacturing process simple and fast, and with low cost.
Accompanying drawing explanation
Fig. 1 is the perspective view of a kind of flexible nervus array in this utility model;
Fig. 2 is the side structure sectional view of a kind of flexible nervus array in this utility model;
Fig. 3 is the side structure schematic diagram that the microelectrode used in the preparation method of a kind of flexible nervus array in this utility model makes template.
The realization of this utility model object, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
Should be appreciated that specific embodiment described herein only in order to explain this utility model, and be not used in restriction this utility model.
This utility model provides a kind of flexible nervus array (can be called for short microelectrode array below), see figures.1.and.2, Fig. 1 is the perspective view of a kind of flexible nervus array in this utility model, Fig. 2 is the side structure sectional view of a kind of flexible nervus array in this utility model, a kind of flexible nervus array comprises flexible substrates 1, insulating barrier 2, microelectrode unit 3, wire 4 and lead solder-joint 5, described microelectrode unit 3, wire 4 and lead solder-joint 5 are arranged in described flexible substrates 1, be connected by described wire 4 between described microelectrode unit 3 and described lead solder-joint 5, described insulating barrier 2 covers in described flexible substrates 1, described microelectrode unit 3 exposes to described insulating barrier 2, described flexible substrates 1 is provided with multiple hollow shape projection 7 exposing to described insulating barrier 2, hollow shape projection 7 is arranged adhesion layer 6, described microelectrode unit 3 is arranged on the adhesion layer 6 of the hollow shape projection 7 of described flexible substrates, microelectrode unit 3 is more easily combined with adhesion layer 6, improve the stability of microelectrode unit 3, make microelectrode unit 3 more firm.
In this utility model, a kind of flexible nervus array adopts the flexible substrates 1 with hollow shape bulge-structure, microelectrode unit 3 is deposited on the adhesion layer 6 in the hollow shape projection 7 in flexible substrates 1, wire 4 is similar to traditional microelectrode array with the set-up mode of lead solder-joint 5, can arrange accordingly by different types of microelectrode array, connected between microelectrode unit 3 and lead solder-joint 5 by wire 4, insulating barrier 2 is covered in flexible substrates 1, and make microelectrode unit 3 expose to insulating barrier 2, in use, when microelectrode array is attached to detected part, compared with traditional microelectrode unit 3, microelectrode unit 3 in this utility model can form larger contact area with detected part, namely the surface area in electrode stimulating site can be increased at the structural microelectrode unit 3 of the convex shape of flexible substrates 1, reduce contact impedance, and, hollow shape bulge-structure in flexible substrates 1 can also reduce the intensity of microelectrode unit 3 electrode site, any damage can not be brought to measured position.
Wherein in a preferred embodiment, insulating barrier 2 is provided with opening in the position of described microelectrode unit 3 and lead solder-joint 5, and described lead solder-joint 5 is exposed by the opening of insulating barrier 2.Insulating barrier 2 can also use the insulating barrier of multiple independent laminated structure, now, making flexible substrates 1, and lay microelectrode unit 3, wire and lead solder-joint 5 in flexible substrates 1 after, only the insulating barrier 2 of multiple independent laminated structure need be covered in flexible substrates 1 and wire 4 is covered, microelectrode unit 3 and lead solder-joint 5 are exposed.
Wherein in a preferred embodiment, the material of described adhesion layer 6 comprises titanium, chromium, or comprises one or both the alloy in these two kinds of elements, and the material of described microelectrode unit 3 is gold.
Wherein in a preferred embodiment, the material of described flexible substrates 1 comprises polydimethylsiloxane, and the material of described insulating barrier comprises can the polydimethylsiloxane of photoetching.
But be noted that the making material of all parts in this utility model is not limited to above-mentioned given material, the conventional alternative material that any those skilled in that art can expect belongs to the equivalent replacement of above-mentioned cited material.
In this utility model, the shape of the projection in flexible substrates 1 is not limited to the hollow hemispherical provided in accompanying drawing, it can also be hollow taper shape, the shapes such as hollow pyramid, rectangular pyramid, polygonal pyramid, hollow hemispherical projections in its effect and this utility model is similar, belong to for equal replacement of the present utility model, will not enumerate at this.
When preparing this utility model, first the microelectrode shown in Fig. 3 is used to make template, spin coating flexible substrates in template is made at microelectrode, multiple projection is had because microelectrode makes in template, the plurality of projection is mated with the hollow convex shape of a kind of flexible nervus array that will prepare, therefore after spin coating flexible substrates, flexible substrates just defines multiple hollow bulge-structure, microelectrode unit is deposited afterwards on hollow bulge-structure, and route wires and lead solder-joint on a flexible substrate, by wire, microelectrode unit and lead solder-joint are coupled together, lay insulating barrier on a flexible substrate afterwards, by described insulating barrier at described microelectrode unit, the position opening of described lead solder-joint, make described microelectrode unit, described lead solder-joint exposes through described insulating barrier, after flexible substrates and the equal coagulation forming of insulating barrier, microelectrode is made template be separated with flexible base layer, obtain described a kind of flexible nervus array, the preparation method simple and fast of a kind of flexible nervus array in this utility model, easy making, and cost of manufacture is cheap, production efficiency is high.
When making this utility model, spin coating one deck polydimethylsiloxane can be made in template as flexible substrates at microelectrode, shape is used to make the identical metal form of template with microelectrode, and the microelectrode unit that will metal form makes with described microelectrode in template, the position that the predeterminated position of wire and lead solder-joint is corresponding arranges opening, metal form is covered in flexible base layer, afterwards by the opening on described metal form, one deck titanium or chromium is deposited as adhesion layer at the boss of flexible base layer, one deck gold is deposited afterwards as microelectrode unit on adhesion layer, route wires and lead solder-joint in flexible base layer, microelectrode unit and lead solder-joint is connected by wire, then the described flexible base layer that described metal form makes template from described microelectrode is separated, use metal form, according to microelectrode unit in flexible substrates, the predeterminated position of wire and lead solder-joint, metal form offers multiple opening accordingly, then metal form is laid on a flexible substrate, afterwards microelectrode unit is set on a flexible substrate by the opening on metal form, wire and lead solder-joint, metal form is removed after connecting between microelectrode unit and lead solder-joint by wire, can the making of convenient microelectrode array.
As this utility model preferred embodiment, the optional material of the adhesion layer in this utility model comprises titanium, chromium, or one or both the alloy comprised in these two kinds of elements, magnetron sputtering method can be adopted titanium or chromium or comprise the boss of one or both the alloy deposition in these two kinds of elements in flexible substrates, the material of described microelectrode unit is gold, the available material of described flexible substrates is including, but not limited to polydimethylsiloxane, and the available material of described insulating barrier includes but are not limited to: can the polydimethylsiloxane of photoetching.
These are only preferred embodiment of the present utility model; not thereby the scope of the claims of the present utility model is limited; every utilize this utility model description and accompanying drawing content to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present utility model.
Claims (5)
1. a flexible nervus array, comprise flexible substrates, insulating barrier, microelectrode unit, wire and lead solder-joint, described microelectrode unit, wire and lead solder-joint are arranged in described flexible substrates, be connected by described wire between described microelectrode unit and described lead solder-joint, described insulating barrier covers in described flexible substrates, described microelectrode unit exposes to described insulating barrier, it is characterized in that, described flexible substrates is provided with multiple hollow shape projection exposing to described insulating barrier, the hollow shape projection of described insulating barrier is provided with adhesion layer, described microelectrode unit is arranged on described adhesion layer.
2. flexible nervus array as claimed in claim 1, it is characterized in that, described insulating barrier is provided with opening in the position of described lead solder-joint, and described lead solder-joint is exposed by the opening of described insulating barrier.
3. flexible nervus array as claimed in claim 1, it is characterized in that, described insulating barrier is made up of multiple lamellar insulant.
4. the flexible nervus array according to any one of claim 1-3, is characterized in that, the material of described adhesion layer comprises titanium, chromium, or comprises one or both the alloy in these two kinds of elements, and the material of described microelectrode unit is gold.
5. the flexible nervus array according to any one of claim 1-3, is characterized in that, the material of described flexible substrates comprises polydimethylsiloxane, and the material of described insulating barrier comprises can the polydimethylsiloxane of photoetching.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520407229.7U CN204767032U (en) | 2015-06-13 | 2015-06-13 | Flexible neural little electrode array |
| PCT/CN2016/076183 WO2016202021A1 (en) | 2015-06-13 | 2016-03-12 | Flexible neural microelectrode array |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520407229.7U CN204767032U (en) | 2015-06-13 | 2015-06-13 | Flexible neural little electrode array |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204767032U true CN204767032U (en) | 2015-11-18 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520407229.7U Expired - Fee Related CN204767032U (en) | 2015-06-13 | 2015-06-13 | Flexible neural little electrode array |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN204767032U (en) |
| WO (1) | WO2016202021A1 (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147280A (en) * | 2015-06-13 | 2015-12-16 | 深圳市前海安测信息技术有限公司 | Flexible neural microelectrode array with hollow projection structure and manufacturing method thereof |
| WO2016202021A1 (en) * | 2015-06-13 | 2016-12-22 | 深圳市华科安测信息技术有限公司 | Flexible neural microelectrode array |
| CN106388807A (en) * | 2016-08-30 | 2017-02-15 | 中国科学院深圳先进技术研究院 | Preparation method for surface adhesive electrode array |
| WO2017219330A1 (en) * | 2016-06-23 | 2017-12-28 | 彭鹏 | Flexible electrode |
| CN109310861A (en) * | 2016-06-14 | 2019-02-05 | 标准有限公司 | Therapeutic device using endoscope-linked electrodes |
| CN117976294A (en) * | 2024-02-26 | 2024-05-03 | 首都医科大学附属北京天坛医院 | An array microelectrode device for mapping the path of the tumor-bearing nerve during schwannoma surgery |
| CN119690243A (en) * | 2024-11-15 | 2025-03-25 | 武汉衷华脑机融合科技发展有限公司 | Flexible microelectrode array, preparation method thereof and brain-computer interface device |
| CN117976294B (en) * | 2024-02-26 | 2026-02-17 | 首都医科大学附属北京天坛医院 | A microelectrode array device for mapping the course of the tumor-bearing nerve during schwannoma surgery. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4914403B2 (en) * | 2008-05-29 | 2012-04-11 | 日本電信電話株式会社 | Extracellular microelectrode and method for producing the same |
| CN101398614B (en) * | 2008-09-12 | 2011-03-16 | 北京大学 | Method for making three-dimensional needlepoint electrode array based on parylene |
| CN103202690B (en) * | 2013-03-14 | 2015-04-15 | 深圳先进技术研究院 | Flexible epicardium electrocardio-electrode chip and preparation method thereof |
| CN204767032U (en) * | 2015-06-13 | 2015-11-18 | 深圳市易特科信息技术有限公司 | Flexible neural little electrode array |
| CN105147280A (en) * | 2015-06-13 | 2015-12-16 | 深圳市前海安测信息技术有限公司 | Flexible neural microelectrode array with hollow projection structure and manufacturing method thereof |
-
2015
- 2015-06-13 CN CN201520407229.7U patent/CN204767032U/en not_active Expired - Fee Related
-
2016
- 2016-03-12 WO PCT/CN2016/076183 patent/WO2016202021A1/en not_active Ceased
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147280A (en) * | 2015-06-13 | 2015-12-16 | 深圳市前海安测信息技术有限公司 | Flexible neural microelectrode array with hollow projection structure and manufacturing method thereof |
| WO2016202021A1 (en) * | 2015-06-13 | 2016-12-22 | 深圳市华科安测信息技术有限公司 | Flexible neural microelectrode array |
| WO2016201746A1 (en) * | 2015-06-13 | 2016-12-22 | 深圳市华科安测信息技术有限公司 | Flexible neural microelectrode array provided with hollow protrusion structure, and manufacturing method therefor |
| CN109310861A (en) * | 2016-06-14 | 2019-02-05 | 标准有限公司 | Therapeutic device using endoscope-linked electrodes |
| WO2017219330A1 (en) * | 2016-06-23 | 2017-12-28 | 彭鹏 | Flexible electrode |
| CN106388807A (en) * | 2016-08-30 | 2017-02-15 | 中国科学院深圳先进技术研究院 | Preparation method for surface adhesive electrode array |
| CN117976294A (en) * | 2024-02-26 | 2024-05-03 | 首都医科大学附属北京天坛医院 | An array microelectrode device for mapping the path of the tumor-bearing nerve during schwannoma surgery |
| CN117976294B (en) * | 2024-02-26 | 2026-02-17 | 首都医科大学附属北京天坛医院 | A microelectrode array device for mapping the course of the tumor-bearing nerve during schwannoma surgery. |
| CN119690243A (en) * | 2024-11-15 | 2025-03-25 | 武汉衷华脑机融合科技发展有限公司 | Flexible microelectrode array, preparation method thereof and brain-computer interface device |
| CN119690243B (en) * | 2024-11-15 | 2025-11-14 | 武汉衷华脑机融合科技发展有限公司 | Flexible microelectrode arrays and their fabrication methods, brain-computer interface devices |
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| WO2016202021A1 (en) | 2016-12-22 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151118 Termination date: 20200613 |
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| CF01 | Termination of patent right due to non-payment of annual fee |