CN204698751U - For the microinjection apparatus of intracranial stereotactic injection - Google Patents
For the microinjection apparatus of intracranial stereotactic injection Download PDFInfo
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- CN204698751U CN204698751U CN201520328267.3U CN201520328267U CN204698751U CN 204698751 U CN204698751 U CN 204698751U CN 201520328267 U CN201520328267 U CN 201520328267U CN 204698751 U CN204698751 U CN 204698751U
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- microsyringe
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Abstract
This utility model relates to a kind of microinjection apparatus for intracranial stereotactic injection, and it comprises: microsyringe, and its tip diameter is 500 μm; Glass needle, its tip diameter is 30 μm, and length is 5 ~ 6 μm; The scalp trocar, its needle tip is socketed the tip of microsyringe after cutting, the hose end socket glass needle of this scalp trocar.Preferably, the length of described glass needle is 5.5 μm.The push rod of described microsyringe is connected with micro-injection delivery side of pump.Because glass material is all less compared with the impact of metal pair tissue and cell, be beneficial to the growth conditions that cell keeps good.This utility model reduces postoperative mortality of animals, improves model success rate; Promote that transplanted cells is survived Growth and Differentiation in host, continue to play therapeutical effect.
Description
Technical field
This utility model relates to medical apparatus technical field, particularly a kind of microinjection apparatus for intracranial stereotactic injection.
Background technology
At present, the aspect such as foundation and central nervous system cell transplanting of cerebral spinal cord injury, degenerative disease model is mainly used in for zooperal stereotaxical injection.After animal head is properly fixed on stereotaxic instrument by the method, with skull bregma for location initial point, determine to inject the accurate location of target spot according to different coordinates, to be punctured cerebral tissue by microsyringe, slow injection related drugs or cell, have the feature such as accurate positioning, stable operation.The microinjection apparatus of current employing includes microsyringe and syringe needle, this needle tip is angle shape, diameter is many at about 500 μm, and mostly be metal material, after this syringe needle enters cerebral tissue, to animal, normal cerebral tissue's damage of such as laboratory mice is comparatively large, easily causes postoperative animal dead; During cell transplantation, because syringe tip is comparatively thick, the cell of diameter number micron is often assembled and is agglomeratingly entered cerebral tissue, affects it and fully contacts with central nervous system's microenvironment, transplants afterwards that cell mortality is high, easily causes the failure of an experiment.In addition, because syringe needle is directly fixedly connected with syringe, syringe end and other equipment connections just become very difficult, cause operation inconvenience.
The information being disclosed in this utility model background technology part is only intended to deepen the understanding to general background technology of the present utility model, and should not be regarded as admitting or imply in any form that this information structure has been prior art known in those skilled in the art.
Utility model content
For deficiency of the prior art, this utility model aims to provide one significantly can improve experiment success rate, and the microinjection apparatus for intracranial stereotactic injection easy and simple to handle.
In order to solve the problem, this utility model provides a kind of microinjection apparatus for intracranial stereotactic injection, and it comprises: microsyringe, and its tip diameter is 500 μm; Glass needle, its tip diameter is 30 μm, and length is 5 ~ 6 μm; The scalp trocar, its needle tip is socketed the tip of microsyringe after cutting, the hose end socket glass needle of this scalp trocar.
Preferably, the length of described glass needle is 5.5 μm.
Preferably, the push rod of described microsyringe is connected with micro-injection delivery side of pump.
The beneficial effects of the utility model: because glass material is all less compared with the impact of metal pair tissue and cell, be beneficial to the growth conditions that cell keeps good.This utility model reduces postoperative mortality of animals, improves model success rate; Promote that transplanted cells is survived Growth and Differentiation in host, continue to play therapeutical effect.
Accompanying drawing explanation
Fig. 1 is the structural representation of the microinjection apparatus for intracranial stereotactic injection of the present utility model.
Detailed description of the invention
As shown in Figure 1, this kind is for the microinjection apparatus of intracranial stereotactic injection, and this device is made up of three parts: microsyringe 1, and its tip diameter is 500 μm (microns).Glass needle 3, its tip draws instrument by microelectrode and is prepared from, and its diameter is 30 μm, and length is 5 ~ 6 μm, and length is preferably 5.5 μm.The scalp trocar 2, its needle tip is socketed the tip of microsyringe after cutting, the other end of the scalp trocar, namely with the end socket glass needle of flexible pipe.During use, the push rod of described microsyringe is connected with the outfan of micro-injection pump (not shown), and this glass needle can be fixed on stereotaxic instrument injection arm.
Flexible pipe pin material in microinjection apparatus after this assembling is softer, can tolerate rotation in all directions, bend.During use, be fixed on by glass needle on stereotaxic instrument injection arm, insert in the draw-in groove of micro pump by the push rod of microsyringe, push rod end and micro-delivery side of pump offset, and regulate micro pump optimum configurations, complete medicine or cell infusion in mouse brain.
Above-described embodiment is for illustrative principle of the present utility model and effect thereof, but this utility model is not limited to above-mentioned embodiment.Those skilled in the art all without prejudice under spirit of the present utility model and category, in claims, can modify to above-described embodiment.Therefore protection domain of the present utility model, should cover as claims of the present utility model.
Claims (3)
1., for a microinjection apparatus for intracranial stereotactic injection, it is characterized in that comprising:
Microsyringe, its tip diameter is 500 μm;
Glass needle, its tip diameter is 30 μm, and length is 5 ~ 6 μm;
The scalp trocar, its needle tip is socketed the tip of microsyringe after cutting, the hose end socket glass needle of this scalp trocar.
2. the microinjection apparatus for intracranial stereotactic injection according to claim 1, is characterized in that: the length of described glass needle is 5.5 μm.
3. the microinjection apparatus for intracranial stereotactic injection according to claim 1, is characterized in that: the push rod of described microsyringe is connected with micro-injection delivery side of pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520328267.3U CN204698751U (en) | 2015-05-20 | 2015-05-20 | For the microinjection apparatus of intracranial stereotactic injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520328267.3U CN204698751U (en) | 2015-05-20 | 2015-05-20 | For the microinjection apparatus of intracranial stereotactic injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204698751U true CN204698751U (en) | 2015-10-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520328267.3U Expired - Fee Related CN204698751U (en) | 2015-05-20 | 2015-05-20 | For the microinjection apparatus of intracranial stereotactic injection |
Country Status (1)
| Country | Link |
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| CN (1) | CN204698751U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198592A (en) * | 2017-05-16 | 2017-09-26 | 于生元 | Rat inflammation soup stimulates model and method for building up |
-
2015
- 2015-05-20 CN CN201520328267.3U patent/CN204698751U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107198592A (en) * | 2017-05-16 | 2017-09-26 | 于生元 | Rat inflammation soup stimulates model and method for building up |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151014 Termination date: 20190520 |
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| CF01 | Termination of patent right due to non-payment of annual fee |