CN209187060U - A kind of rat ventricles of the brain microinjection casing - Google Patents
A kind of rat ventricles of the brain microinjection casing Download PDFInfo
- Publication number
- CN209187060U CN209187060U CN201821391877.8U CN201821391877U CN209187060U CN 209187060 U CN209187060 U CN 209187060U CN 201821391877 U CN201821391877 U CN 201821391877U CN 209187060 U CN209187060 U CN 209187060U
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- circular
- base support
- casing
- support
- tube core
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Abstract
The utility model relates to a kind of rat ventricles of the brain microinjection casings, including circular-base support, casing and U-tube core, the circular-base support with stereotaxic apparatus for being fixedly connected, two through-holes of interval setting in the circular-base support, described sleeve pipe is two and the side of the circular-base support is arranged in, one end of described sleeve pipe is fixed in the through-hole of the circular-base support, the U-tube core includes two support arms and the interconnecting piece between two support arms, two support arms are slidably disposed in described sleeve pipe after penetrating the through-hole from the other side of the circular-base support；The circular-base support uses plastic material, and described sleeve pipe and U-tube core use tungsten material.Material of the utility model due to improving circular-base support, casing and U-tube core, improved device carries out the scanning of magnetic resonance imaging while setting pipe, and has preferable histocompatbility.
Description
Technical field
The utility model relates to a kind of rat ventricles of the brain microinjection casings, belong to herding field.
Background technique
With the progress of neuroimaging especially mr imaging technique, physiology and pathological state are non-invasively observed in body
Hypencephalon institutional framework and function are changed as the important means of modern medicine study.Since the building of related brain disease model can not
Human body realize, must by the carrier of experimental animal, in numerous experimental animal kinds, rodent toy such as rat,
Mouse is most commonly used to animal iconography research.But due to the special physiological of blood-brain barrier (Blood brain barrier, BBB)
Structure, high amount of drug can not enter the blood circulation of brain through BBB, it is therefore desirable to pass through the positioning of three-dimensional brain and ventricles of the brain microinjection
Method establishes the drug model of animal.
There are some problems in use for existing ventricles of the brain microinjection trochar: 1, using common stainless steel mostly at present
As tube body material, the scanning of magnetic resonance imaging first cannot be carried out while setting pipe, second histocompatbility is poor；2, collet
It is thicker, make magnetic resonance head coil that can not be close to and wrap up skull, subsequent image scan can not carry out；3, in activities in rats process
In the influences such as hit, scratched and be easy to fall off.
Therefore, it needs to develop a kind of rat ventricles of the brain microinjection casing that can be more applicable for magnetic resonance environment, makes correlation
Magnetic resonance imaging experiment can be gone on smoothly.
Summary of the invention
In view of the above problems, the object of the present invention is to provide the rats that one kind can be more applicable for magnetic resonance environment
Ventricles of the brain microinjection casing.
To achieve the above object, the utility model uses a kind of following technical scheme: rat ventricles of the brain microinjection casing,
It is characterized in that, including circular-base support, casing and U-tube core, the circular-base support is used for and the fixed company of stereotaxic apparatus
It connects, two through-holes of interval setting in the circular-base support, described sleeve pipe is two and the circular-base support is arranged in
Side, one end of described sleeve pipe are fixed in the through-hole of the circular-base support, and the U-tube core includes two support arms and is located at
Interconnecting piece between two support arms, two support arms penetrate after the through-hole slidably from the other side of the circular-base support
Ground is arranged in described sleeve pipe；The circular-base support uses plastic material, and described sleeve pipe and U-tube core use tungsten material.
The circular-base support be taper platform structure, the circular-base support with a thickness of 0.2cm, backing circular diameter is
1.0cm, the internal diameter of described sleeve pipe are 0.05cm, and length is 0.8~1.0cm；The diameter of the U-tube core is 0.04cm, length
For 1~1.2cm.
The other side of the circular-base support is provided with groove, line setting of the groove along two through-holes.
It is additionally provided with second groove 5 in the other side of the circular-base support, the second groove is intersected with the groove
Arrangement.
Because the utility model adopts the above technical scheme, it has the following advantages: 1, the utility model is due to improving
The material of circular-base support, casing and U-tube core, improved device carry out the scanning of magnetic resonance imaging while setting pipe, and
And there is preferable histocompatbility.2, the thickness limit of circular-base support is 0.2cm, the circle of this thickness by the utility model
Substrate support can either firmly fix metal tube, can also head coil be made to be bonded skull as far as possible, reduce the puppet of magnetic resonance imaging
Shadow.3, since improved circular-base support is relatively thin, diameter is smaller, to prevent dental cement loosening from leading to tube displacement, this reality
Circular-base support is designed as taper platform structure with novel, to increase the contact area of circular-base support and dental cement, makes to cover
Pipe is fixed more secured.4, due to needing the stringent height for limiting circular-base support, the utility model is by die design at U
U-tube core is put back into casing the thickness that will not increase casing entirety after the completion of intracerebroventricular by type.5, the utility model
The trench design of shoe surface facilitates operator to take out U-tube core using tools such as ophthalmic tweezers, pins.
Detailed description of the invention
Fig. 1 is the overall structure diagram of the utility model.
Specific embodiment
The utility model is described in detail with reference to the accompanying drawings and examples.
As shown in Figure 1, the utility model proposes a kind of rat ventricles of the brain microinjection casing, including circular-base support 1, set
Pipe 2 and U-tube core 3.Wherein, circular-base support 1 is spaced in circular-base support 1 for being fixedly connected with stereotaxic apparatus
Two through-holes are set.Casing 2 is two and the side of circular-base support 1 is arranged in, and circular-base support is fixed in one end of casing 2
In 1 through-hole.U-tube core 3 includes two support arms and the interconnecting piece between two support arms.Two support arms are from circular-base support
1 other side is slidably disposed in casing 2 after penetrating through-hole.Circular-base support 1 uses plastic material, casing 2 and U-tube
Core 3 uses tungsten material.
Further, circular-base support 1 be taper platform structure, circular-base support 1 with a thickness of 0.2cm, backing circular diameter
For 1.0cm；The internal diameter of casing 2 is 0.05cm, and length is 0.8~1.0cm；The diameter of U-tube core 3 be 0.04cm, length be 1~
1.2cm。
Further, the other side of circular-base support 1 being provided with groove 4, groove 4 is arranged along the line of two through-holes,
Due to needing the height of strict control circular-base support 1, after U-tube core 3 is completely into casing 2, interconnecting piece can not have
Enter in groove 4, to not increase the integral thickness of circular-base support 1.
Further, it is additionally provided with groove 5, groove 5 and 4 arranged crosswise of groove in the other side of circular-base support 1, needed
When U-tube core 3 is taken out, the setting of groove 5 is so that U-shaped convenient for being taken out using the help of the auxiliary tools such as ophthalmic tweezers, pin
Tube core 3.
The utility model use process is as follows: in laboratory, circular-base support 1 is fixed on stereotaxic apparatus,
Then using glass ionomer that casing 2 and circular-base support 1 is whole by the telocoele of the end merging rat of casing 2
It is fixed with Rat calvarial.Casing 2 is placed in after making intracerebroventricular, then by U-tube core 3 to block the connection of the ventricles of the brain and air
System keeps the opposite airtightness and aseptic of ventricles of the brain environment.
The utility model is only illustrated with above-described embodiment, and structure, setting position and its connection of each component are all can
With what is be varied.It is all that individual part is carried out according to the utility model principle on the basis of technical solutions of the utility model
Improvement or equivalents, should not exclude except the protection scope of the utility model.
Claims (4)
1. a kind of rat ventricles of the brain microinjection casing, which is characterized in that including circular-base support, casing and U-tube core, the circle
Shape substrate support with stereotaxic apparatus for being fixedly connected, two through-holes of interval setting, the set in the circular-base support
Pipe is two and the side of the circular-base support is arranged in, and the through-hole of the circular-base support is fixed in one end of described sleeve pipe
In, the U-tube core includes two support arms and the interconnecting piece between two support arms, and two support arms are from the round base
The other side of collet is slidably disposed in described sleeve pipe after penetrating the through-hole；The circular-base support uses plastics material
Matter, described sleeve pipe and U-tube core use tungsten material.
2. a kind of rat ventricles of the brain microinjection casing as described in claim 1, which is characterized in that the circular-base support is cone
Shape platform structure, the circular-base support with a thickness of 0.2cm, backing circular diameter is 1.0cm, and the internal diameter of described sleeve pipe is
0.05cm, length are 0.8~1.0cm；The diameter of the U-tube core is 0.04cm, and length is 1~1.2cm.
3. a kind of rat ventricles of the brain microinjection casing as claimed in claim 1 or 2, which is characterized in that in the circular-base
The other side of support is provided with groove, line setting of the groove along two through-holes.
4. a kind of rat ventricles of the brain microinjection casing as claimed in claim 3, which is characterized in that in the circular-base support
The other side is additionally provided with second groove, the second groove and the groove arranged crosswise.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821391877.8U CN209187060U (en) | 2018-08-28 | 2018-08-28 | A kind of rat ventricles of the brain microinjection casing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821391877.8U CN209187060U (en) | 2018-08-28 | 2018-08-28 | A kind of rat ventricles of the brain microinjection casing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209187060U true CN209187060U (en) | 2019-08-02 |
Family
ID=67405277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821391877.8U Active CN209187060U (en) | 2018-08-28 | 2018-08-28 | A kind of rat ventricles of the brain microinjection casing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209187060U (en) |
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2018
- 2018-08-28 CN CN201821391877.8U patent/CN209187060U/en active Active
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