CN204613225U - Autopipette - Google Patents
Autopipette Download PDFInfo
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- CN204613225U CN204613225U CN201520165076.XU CN201520165076U CN204613225U CN 204613225 U CN204613225 U CN 204613225U CN 201520165076 U CN201520165076 U CN 201520165076U CN 204613225 U CN204613225 U CN 204613225U
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Abstract
The utility model relates to a kind of detection application of sample instrument, especially a kind of autopipette, belongs to container or the vessel technical field of use for laboratory.Comprise worktable, control box, mobile sample adding device and automatic liquid feeder, this sample injector also comprises reaction plate memory storage, described reaction plate memory storage comprises along the movable cylinder fixed mount of reaction plate application of sample rear cabinet tank wall, the top of cylinder fixed mount is fixed with lifting cylinder, reaction plate fixed mount comprises a horizontal direction fixed head and is positioned at the vertical direction fixed head at horizontal direction fixed head two ends, the inner side of vertical direction fixed head is provided with fixed lobe, the inside of described suction post is provided with soup stick moving up and down, and soup stick is connected with upper and lower air cylinders.Achieve automatic sample, improve application of sample efficiency and application of sample precision, and effectively prevent from polluting experimental facilities and reagent in application of sample process.
Description
Technical field
The utility model relates to a kind of detection application of sample instrument, especially a kind of autopipette, belongs to container or the vessel technical field of use for laboratory.
Background technology
At present, in the experiment of biological study and detection, as in serum blood examination survey, hemagglutination test, agglutination test, agglutination test or ELISA detection, conventional detection method generally comprises following steps: first join in elisa plate by testing sample serum by sample pin, then joined in elisa plate by reagent needles abstraction reaction reagent and react, afterwards after hatching, wash plate and colour developing, carry out reading value, and according to reading value result of determination.Wherein, serum joined elisa plate, add reactant liquor or dilution to elisa plate and add washing lotion in the process of elisa plate, all relating to distribution and the transfer of test specimen, in working order, is all generally by realizing in the above-mentioned course of work in manual operation.Its defect existed is: (1) manually-operated inefficiency; (2) very easily produce personal error in manual operation, distribute with the accuracy of transfer poor, operate miss is large; (3) experimental facilities and the contaminated danger of operating personnel is easily caused.Therefore existing detection method is difficult to realize extensive, large batch of efficient detection.
Utility model content
The purpose of this utility model is to propose a kind of autopipette, which overcome the above-mentioned defect that existing sample injector exists, achieve automatic sample, improve application of sample efficiency and application of sample precision, and effectively prevent from polluting experimental facilities and reagent in application of sample process.
The utility model adopts following technical scheme to realize: a kind of autopipette, comprise worktable, control box, mobile sample adding device and automatic liquid feeder, wherein, mobile sample adding device and automatic liquid feeder are arranged on the table, worktable is provided with portal frame, control box is fixed on portal frame, worktable is provided with water dropper box successively, case before kit and application of sample, the worktable corresponding with automatic liquid feeder place is provided with kit, reaction plate is provided with in case before application of sample, wherein, this sample injector also comprises reaction plate memory storage, the worktable that before application of sample, case is corresponding is provided with reaction plate propulsion cylinder, the worktable that application of sample rear cabinet is corresponding is provided with reaction plate and releases cylinder, at reaction plate memory storage, place is provided with application of sample rear cabinet, application of sample rear cabinet place is provided with reaction plate storage rack, described reaction plate memory storage comprises along the movable cylinder fixed mount of reaction plate application of sample rear cabinet tank wall, the top of cylinder fixed mount is fixed with lifting cylinder, the side of cylinder fixed mount is provided with mobile cylinder, the bottom of cylinder fixed mount is fixed with suction post, inhale post to be connected with lifting cylinder, the bottom of inhaling post is provided with sucker, inhale on post and be fixed with reaction plate fixed mount, reaction plate fixed mount comprises a horizontal direction fixed head and is positioned at the vertical direction fixed head at horizontal direction fixed head two ends, the inner side of vertical direction fixed head is provided with fixed lobe, the inside of described suction post is provided with soup stick moving up and down, soup stick is connected with upper and lower air cylinders.
In the utility model, described mobile sample adding device comprises two sliding axles be parallel to each other up and down of horizontally set, screw rod is provided with between two sliding axles, one end of screw rod is connected with the output terminal of stepper motor, stepper motor is fixed on portal frame, and sliding axle and screw rod are provided with application of sample travelling carriage, and application of sample travelling carriage is along sliding axle and screw slide, application of sample travelling carriage is provided with upper and lower air cylinders and jig coupling shaft, upper and lower air cylinders is connected with jig coupling shaft; Jig coupling shaft is fixed with sample injector jig, upper and lower air cylinders is connected with sample injector jig; Sample injector jig is fixed with sample injector, application of sample cylinder and water dropper and unloads carrier gas cylinder, application of sample cylinder is connected with sample injector.
Described automatic liquid feeder comprises bottle rack, reagent bottle, emulsion tube and liquid measure control cylinder, wherein bottle rack is fixed on portal frame, reagent bottle is placed on bottle rack, one end of emulsion tube is connected with reagent bottle, the other end is arranged on the top of kit, liquid measure control cylinder is arranged on emulsion tube, and liquid measure control cylinder is connected with control box, is provided with reagent solution face sensor in kit.
Shown reaction plate storage rack comprises the spaced demixing plate for placing response plate from top to bottom.In order to prevent the reagent in reaction plate contaminated, the upper surface of reaction plate arranges reaction plate lid.
In the utility model, the action of all cylinders controls by control box, water dropper box, kit and reaction plate are equipped with position transducer, and corresponding setting position identification sensor on sample injector, for identifying the position in each hole on each water dropper, kit and reaction plate on each water dropper box.
The beneficial effects of the utility model are:
(1) this autopipette fully achieves the automatic sample of reagent, substantially increases application of sample efficiency;
(2) application of sample of this autopipette is realized by controller, avoids the error produced in manual operation, improves application of sample precision;
(3) because application of sample process is realized by machine completely, therefore effectively prevent experimenter in operating process from polluting experimental facilities and utensil, the reagent in reaction plate can be prevented contaminated by reaction plate lid, ensure that the security of reagent and pure property.
Accompanying drawing explanation
Fig. 1 is the first perspective view of the present utility model;
Fig. 2 is the second perspective view of the present utility model;
Fig. 3 is front view of the present utility model;
Fig. 4 is vertical view of the present utility model;
Fig. 5 is that F-F in Fig. 3 is to cut-open view;
Fig. 6 is left view of the present utility model;
Fig. 7 is the front view of reaction plate memory storage in the utility model.
In figure: 1 water dropper box; 2 kits; 3 reaction plates; 4 application of sample rear cabinets; 5 application of sample travelling carriages; 6 sample injector jigs; 7 sample injectors; 8 portal frames; Case before 9 application of samples; 10 control boxs; 11 stepper motors; 12 water droppers unload carrier gas cylinder; 13 application of sample cylinders; 14 upper and lower air cylinders; 15 lifting cylinders; 16 liquid measure control cylinders; 17 sliding axles; 18 screw rods; 19 reagent bottles; 20 bottle racks; 21 emulsion tubes; 22 reaction plate propulsion cylinders; 23 reaction plates release cylinder; 24 worktable; 25 jig coupling shafts; 26 move cylinder; 27 inhale post; 28 reaction plate fixed mounts; 29 fixed lobes; 30 reaction plate storage rack; 31 cylinder fixed mounts; 32 demixing plates.
Embodiment
Below in conjunction with drawings and Examples, the utility model is described further.
Embodiment 1
As shown in Figure 1, this autopipette comprises worktable 24, control box 10, mobile sample adding device, automatic liquid feeder and reaction plate memory storage, and mobile sample adding device, automatic liquid feeder and reaction plate memory storage are successively set on worktable 24.Worktable 24 is provided with portal frame 8, and control box 10 is fixed on portal frame 8.Worktable 24 is provided with successively case 9 and application of sample rear cabinet 4 before water dropper box 1 and kit 2, application of sample, wherein corresponding with automatic liquid feeder place worktable 24 is provided with kit 2, and at reaction plate memory storage, place is provided with application of sample rear cabinet 4.Be provided with reaction plate 3 in case 9 before application of sample, before application of sample, the worktable 24 of case 9 correspondence is provided with reaction plate propulsion cylinder 22, and the worktable 24 of application of sample rear cabinet 4 correspondence is provided with reaction plate and releases cylinder 23.
Be provided with screw rod 18 between 17, two sliding axles 17 of two sliding axles be parallel to each other up and down that described mobile sample adding device comprises horizontally set, one end of screw rod 18 is connected with the output terminal of stepper motor 11, and stepper motor 11 is fixed on portal frame 8.Sliding axle 17 and screw rod 18 are provided with application of sample travelling carriage 5, and application of sample travelling carriage 5 can slide along sliding axle 17 and screw rod 18.Application of sample travelling carriage 5 is provided with upper and lower air cylinders 14 and jig coupling shaft 25, upper and lower air cylinders 14 is connected with jig coupling shaft 25; Jig coupling shaft 25 is provided with sample injector jig 6, and upper and lower air cylinders 14 is connected with sample injector jig 6; Sample injector jig 6 is provided with sample injector 7, application of sample cylinder 13 and water dropper and unloads carrier gas cylinder 12, and application of sample cylinder 13 is connected with sample injector 7.
Described automatic liquid feeder comprises bottle rack 20, reagent bottle 19, emulsion tube 21 and liquid measure control cylinder 16, wherein bottle rack 20 is fixed on portal frame 8, reagent bottle 19 is placed on bottle rack 20, and one end of emulsion tube 21 is connected with reagent bottle 19, and the other end is arranged on the top of kit 2.Liquid measure control cylinder 16 is arranged on emulsion tube 21, and liquid measure control cylinder 16 is connected with control box 10.Reagent solution face sensor is provided with in kit 2, when the reagent liquid level in kit 2 drops to a certain degree, control box 10 controls liquid measure control cylinder 16 and opens, reagent in reagent bottle 19 flow in kit 2 by emulsion tube 21, play the effect of supplementary reagent, the flow of reagent also can be controlled by liquid measure control cylinder 16.
Described reaction plate memory storage comprises cylinder fixed mount 31, and described cylinder fixed mount 31 can move forward and backward along the tank wall of reaction plate application of sample rear cabinet 4.The top of cylinder fixed mount 31 is fixed with lifting cylinder 15, and the side of cylinder fixed mount 31 is provided with mobile cylinder 26, and the bottom of cylinder fixed mount 31 is fixed with inhales post 27, inhales post 27 and is connected with lifting cylinder 15.The bottom of inhaling post 27 is provided with sucker, inhale on post 27 and be fixed with reaction plate fixed mount 28, reaction plate fixed mount 28 comprises a horizontal direction fixed head and is positioned at the vertical direction fixed head at horizontal direction fixed head two ends, and the inner side of vertical direction fixed head is provided with fixed lobe 29.The inside of described suction post 27 is provided with soup stick moving up and down, and soup stick is controlled by upper and lower air cylinders 14.Shown reaction plate storage rack 30 arranges demixing plate 32 in interval from top to bottom, and reaction plate 3 is placed on each demixing plate 32.In order to prevent the reagent in reaction plate 3 contaminated, the upper surface of reaction plate 3 arranges reaction plate lid.By lifting cylinder 15 and suction post 27, can realize reaction plate lid being moved to reaction plate 3 upper surface filling reagent, and reaction plate 3 be moved on each demixing plate 32 of demixing plate 32 reaction plate storage rack 30.When upper and lower air cylinders 14 drives soup stick to rise, make to form negative pressure in suction post 27, thus drive sucker to be picked up by reaction plate lid; When reaction plate lid is put to the upper surface of reaction plate 3, reaction plate fixed mount 28 is fixedly connected with reaction plate by the fixed lobe 29 on its vertical direction fixed head, by lifting cylinder 15 and mobile cylinder 26, reaction plate 3 is moved to after in reaction plate storage rack 30, upper and lower air cylinders 14 drives soup stick to decline, the negative pressure of inhaling in post 27 is released, and makes sucker release reaction plate lid; Upper and lower air cylinders 14 drives soup stick to continue to decline, until soup stick contacts with reaction plate lid with sucker, and downward pressure is applied to reaction plate lid, execute in stressed process, fixed projection 29 on reaction plate fixed mount 28 is separated gradually with reaction plate 3, until reaction plate fixed mount 28 is separated completely with reaction plate 3, thus reaction plate 3 is placed on each demixing plate 32.
Embodiment 2
In the utility model, the action of all cylinders controls by control box 10, water dropper box 1, kit 2 and reaction plate 3 are provided with position transducer, simultaneously location identification sensor on sample injector 7, for identifying the position in each hole on each water dropper, kit 2 and reaction plate 3 on each water dropper box 1.
Utilize the course of work of this sample injector as described below:
First, worktable 24 is put into water dropper box 1, kit 2 successively; Before application of sample in case 9, put into some reaction plates 3; Sample injector 7 is laid in sample injector jig 6; Bottle rack 20 is laid reagent bottle 19, emulsion tube 21 is installed, by liquid measure control cylinder 16, guides on kit 2.
Second step, starts application of sample: press the startup button on control box 10, stepper motor 11 runs, and by screw rod 18, drives application of sample travelling carriage 5 to move to water dropper box 1 position, and accurately navigates to the position of water dropper.Upper and lower air cylinders 14 drives sample injector jig 6 to run down to position, after making each tube head on sample injector 7 accurately enter corresponding water dropper, sample injector jig 6 moves on to position, completes and add water dropper work.Meanwhile, reaction plate propulsion cylinder 22 promotes a deblocking reaction plate 3 and arrives load position accurately, and once, quantitative reagent filling is in kit 2 in liquid measure control cylinder 16 action.Stepper motor 11 drives sample injector jig 6 to kit 2 position, and upper and lower air cylinders 14 drives sample injector jig 6 to move down and puts in place, application of sample cylinder 13 action, and each water dropper gets liquid, completes and gets liquid work.Upper and lower air cylinders 14 drives on sample injector jig 6 and moves on to position.Stepper motor 11 drives sample injector jig 6 to be shifted to the right to the first row position of reaction plate 3.Upper and lower air cylinders 14 drives sample injector jig 6 to move down and puts in place, and each water dropper enters in the hole of reaction plate 3.Application of sample cylinder 13 action, each water dropper fluid, completes the application of sample work of first row.Then, liquid is got in the position that stepper motor 11 drives sample injector jig 6 to move left to kit 2, moves to right to reaction plate 3 second row, completes the application of sample work of second row.By that analogy, reaction plate 3 all application of sample work is completed.
When after the whole application of sample work completing a reaction plate 3, stepper motor 11 drives sample injector jig 6 to move to right out to add model 3, and water dropper unloads carrier gas cylinder 12 action once, unloads all water droppers.Simultaneously, reaction plate releases cylinder 23 action, the reaction plate 3 completing application of sample is released in application of sample rear cabinet 4, lifting cylinder 15 action once, by soup stick, reaction plate lid is placed on the upper surface of reaction plate 3, by lifting cylinder 15, the fixed lobe 29 on reaction plate fixed mount 28 is connected with reaction plate 3 sidewall, the clearance fit simultaneously between fixed lobe 29 and reaction plate 3 sidewall, realization response plate fixed mount 28 is fixedly connected with reaction plate 3 simultaneously.Then lifting cylinder 15 and mobile cylinder 26 action, promote reaction plate 3 and move to reaction plate storage rack 30 place, lifting cylinder 15 action again, put by reaction plate 3 on each demixing plate 32.
In the above-mentioned course of work, when the liquid level in kit 2 is reduced to a certain degree, once, quantitative is filled into reagent in kit 2 in liquid measure control cylinder 16 action.After the reaction plate 3 in case before application of sample 9 all completes application of sample work, equipment quits work, and the reaction plate 3 after application of sample, all in application of sample rear cabinet 4, completes whole application of sample task.
Embodiment 3
Reaction plate memory storage can be expanded by the utility model, and both can arrange in Integral operating platform 24 front end, and also can arrange on the right side of worktable 24, object is all pick and place reaction plate 3 fast.Because be all the automation mechanized operation for elisa plate at present, and other follow-up operations still need manual operations.Reaction plate memory storage is set in front end, can works as after reaction plate 3 piled with, more be convenient to experimenter and remove reaction plate 3.
Based on other extended modes of the present embodiment, do not enumerate, all in the protection domain of the requirement of utility model.
Claims (5)
1. an autopipette, comprise worktable (24), control box (10), mobile sample adding device and automatic liquid feeder, wherein, mobile sample adding device and automatic liquid feeder are arranged on worktable (24), worktable (24) is provided with portal frame (8), control box (10) is fixed on portal frame (8), worktable (24) is disposed with water dropper box (1), case (9) before kit (2) and application of sample, the worktable (24) corresponding with automatic liquid feeder place is provided with kit (2), reaction plate (3) is provided with in case (9) before application of sample, it is characterized in that: this sample injector also comprises reaction plate memory storage, the worktable (24) that before application of sample, case (9) is corresponding is provided with reaction plate propulsion cylinder (22), the worktable (24) that application of sample rear cabinet (4) is corresponding is provided with reaction plate and releases cylinder (23), application of sample rear cabinet (4) is provided with at reaction plate memory storage place, application of sample rear cabinet (4) place is provided with reaction plate storage rack (30),
Described reaction plate memory storage comprises along the movable cylinder fixed mount (31) of reaction plate application of sample rear cabinet (4) tank wall, the top of cylinder fixed mount (31) is fixed with lifting cylinder (15), the side of cylinder fixed mount (31) is provided with mobile cylinder (26), the bottom of cylinder fixed mount (31) is fixed with inhales post (27), inhale post (27) to be connected with lifting cylinder (15), the bottom of inhaling post (27) is provided with sucker, inhale on post (27) and be fixed with reaction plate fixed mount (28), reaction plate fixed mount (28) comprises a horizontal direction fixed head and is positioned at the vertical direction fixed head at horizontal direction fixed head two ends, the inner side of vertical direction fixed head is provided with fixed lobe (29), the inside of described suction post (27) is provided with soup stick moving up and down, soup stick is connected with upper and lower air cylinders (14).
2. autopipette according to claim 1, it is characterized in that: described mobile sample adding device comprises two sliding axles be parallel to each other (17) up and down of horizontally set, screw rod (18) is provided with between two sliding axles (17), one end of screw rod (18) is connected with the output terminal of stepper motor (11), stepper motor (11) is fixed on portal frame (8), sliding axle (17) and screw rod (18) are provided with application of sample travelling carriage (5), application of sample travelling carriage (5) slides along sliding axle (17) and screw rod (18), application of sample travelling carriage (5) is provided with upper and lower air cylinders (14) and jig coupling shaft (25), upper and lower air cylinders (14) is connected with jig coupling shaft (25), jig coupling shaft (25) is fixed with sample injector jig (6), upper and lower air cylinders (14) is connected with sample injector jig (6), sample injector jig (6) is fixed with sample injector (7), application of sample cylinder (13) and water dropper and unloads carrier gas cylinder (12), application of sample cylinder (13) is connected with sample injector (7).
3. autopipette according to claim 1, it is characterized in that: described automatic liquid feeder comprises bottle rack (20), reagent bottle (19), emulsion tube (21) and liquid measure control cylinder (16), wherein bottle rack (20) is fixed on portal frame (8), reagent bottle (19) is placed on bottle rack (20), one end of emulsion tube (21) is connected with reagent bottle (19), the other end is arranged on the top of kit (2), liquid measure control cylinder (16) is arranged on emulsion tube (21), liquid measure control cylinder (16) is connected with control box (10), kit is provided with reagent solution face sensor in (2).
4. autopipette according to claim 1, is characterized in that: described reaction plate storage rack (30) comprises the spaced demixing plate for placing response plate (3) (32) from top to bottom.
5. autopipette according to claim 1, it is characterized in that: described water dropper box (1), kit (2) and reaction plate (3) are equipped with position transducer, corresponding setting position identification sensor on sample injector (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520165076.XU CN204613225U (en) | 2015-03-23 | 2015-03-23 | Autopipette |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520165076.XU CN204613225U (en) | 2015-03-23 | 2015-03-23 | Autopipette |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204613225U true CN204613225U (en) | 2015-09-02 |
Family
ID=53965774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520165076.XU Withdrawn - After Issue CN204613225U (en) | 2015-03-23 | 2015-03-23 | Autopipette |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204613225U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104698205A (en) * | 2015-03-23 | 2015-06-10 | 中国动物卫生与流行病学中心 | Automatic sample injector |
| CN108554468A (en) * | 2018-04-17 | 2018-09-21 | 贵州省中国科学院天然产物化学重点实验室 | A kind of mechanical structure of autopipette |
-
2015
- 2015-03-23 CN CN201520165076.XU patent/CN204613225U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104698205A (en) * | 2015-03-23 | 2015-06-10 | 中国动物卫生与流行病学中心 | Automatic sample injector |
| CN108554468A (en) * | 2018-04-17 | 2018-09-21 | 贵州省中国科学院天然产物化学重点实验室 | A kind of mechanical structure of autopipette |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20150902 Effective date of abandoning: 20160511 |
|
| C25 | Abandonment of patent right or utility model to avoid double patenting |