CN204575619U - A kind of device that is fixed and clamped for the miniature flow cell of PDMS - Google Patents
A kind of device that is fixed and clamped for the miniature flow cell of PDMS Download PDFInfo
- Publication number
- CN204575619U CN204575619U CN201520241382.7U CN201520241382U CN204575619U CN 204575619 U CN204575619 U CN 204575619U CN 201520241382 U CN201520241382 U CN 201520241382U CN 204575619 U CN204575619 U CN 204575619U
- Authority
- CN
- China
- Prior art keywords
- flow cell
- pdms
- fixed
- base
- clamped
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
- 239000004205 dimethyl polysiloxane Substances 0.000 title claims abstract description 32
- 235000013870 dimethyl polysiloxane Nutrition 0.000 title claims abstract description 32
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 title claims abstract description 32
- 238000004987 plasma desorption mass spectroscopy Methods 0.000 title claims abstract description 32
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 title claims abstract description 32
- 238000003825 pressing Methods 0.000 claims description 15
- 210000004907 gland Anatomy 0.000 claims description 11
- 238000010276 construction Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 230000001105 regulatory effect Effects 0.000 abstract description 4
- 239000007788 liquid Substances 0.000 description 23
- 239000012530 fluid Substances 0.000 description 11
- 230000006835 compression Effects 0.000 description 7
- 238000007906 compression Methods 0.000 description 7
- 239000012528 membrane Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000005672 electromagnetic field Effects 0.000 description 3
- 238000013016 damping Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 238000013475 authorization Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Polymers C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000013139 quantization Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a kind of device that is fixed and clamped for the miniature flow cell of PDMS, comprise worktable, and install on the table for carrying the base of the miniature flow cell of PDMS, also comprise and to be arranged on this worktable and across the stand frame of base, the top vertical of described stand frame is provided with spiral micrometer head, the micrometric screw of described spiral micrometer head is as depression bar, and its end passes the top of stand frame towards base.The device that is fixed and clamped for the miniature flow cell of PDMS of the present utility model, owing to adopting spiral micrometer head as the regulating device of the miniature flow cell of PDMS and base snap-in force, therefore can be carried out the size of controlled pressure by the scale on spiral micrometer head when fixing flow cell, rapid adjustment is to suitable position, thus minimizing number of operations, improve operating efficiency, avoid the infringement repeatedly adjusting and flow cell is caused simultaneously.
Description
Technical field
The utility model relates to a kind of hold down gag, particularly a kind of device that is fixed and clamped for the miniature flow cell of PDMS.
Background technology
Dimethyl silicone polymer (Polydimethylsiloxane, PDMS) silicon rubber is commonly called as, low by means of its cost, good chemical inertness, good adhesion between same silicon chip, sheet metal, glass sheet, and the advantages such as multiple modifying and decorating can be carried out on surface, in recent years, be widely used in the field such as micro-fluidic.
As shown in Figure 3, the miniature flow cell 6 of PDMS comprises: base plate 61 is with in the PDMS module 62, figure be fixed on base plate, and upward, during actual use, generally install down, base plate 61 is provided with inlet 63, liquid outlet 64 and pilot hole 65 to PDMS module 62.
In the use procedure of the miniature flow cell of PDMS, need itself and mounting surface are carried out fitting and gives certain snap-in force.Whether this snap-in force is suitable extremely important, if too small meeting causes flow cell to occur the phenomenon of leakage, excessive, solution can be made to circulate not smooth, and may cause damage to flow cell.The compression mode of flow cell generally adopted and placed one piece of weight above it in the past, and then installed a screw tightening above.
Authorization Notice No. CN 100549683C patent document discloses a kind of multifunctional micro-electrode chip circulation detecting pool device, lower platen upper surface is embedded with electromagnetic field coil, dual-side is respectively equipped with guide rail electrode, and guide rail electrode is electrically connected with the coil lead of electromagnetic field coil respectively; Elastic membrane lower surface is embedded with micro-electrode chip, and upper surface has circulation groove; Top board dual-side is respectively equipped with guide rail electrode, and guide rail electrode is electrically connected with the contact conductor of micro-electrode chip respectively, and top board has fluid intake and fluid egress point; Top board, lower platen and elastic membrane are fixed by set bolt, two pipe jointers respectively Pipe installing at the fluid intake (inlet) of top board and fluid egress point (liquid outlet); Wherein micro-electrode chip is positioned at the below of elastic membrane and is positioned at the top of lower platen, electromagnetic field coil is positioned at the below of micro-electrode chip and is positioned at the top of lower platen, fluid intake and fluid egress point are aligned in the two-port of elastic membrane circulation groove respectively, this invention structure is simple, function is advanced, it is convenient to install and clean, and the fields such as biology, chemistry, life science that can be used in widely use.
Adopt and there is certain defect in this way, one be at every turn to the adjustment of screw (set bolt) be all fluid situation by checking liquid outlet and flow cell whether leakage just can know whether and be screwed to suitable position and whether snap-in force is now applicable to, judge by rule of thumb primarily of operating personnel, cannot accomplish the control of digital quantization, and regulated efficiency is low, weak effect; Two is the meaningless adjustment of screw position when using, itself can cause damage, thus shorten serviceable life of flow cell, improve experimental cost to the miniature flow cell of PDMS.Therefore, design suitable hold down gag, for micro-fluidic chip and apply extremely important.
Utility model content
The utility model provides a kind of device that is fixed and clamped for the miniature flow cell of PDMS, and structure is simple, compresses effective, easy to adjust, quick.
A kind of device that is fixed and clamped for the miniature flow cell of PDMS, comprise worktable, and install on the table for carrying the base of the miniature flow cell of PDMS, also comprise and to be arranged on this worktable and across the stand frame of base, the top vertical of described stand frame is provided with spiral micrometer head, the micrometric screw of described spiral micrometer head is as depression bar, and its end passes the top of stand frame towards base.
When the utility model uses, first miniature for PDMS flow cell (hereinafter referred to as flow cell) is placed on base, the below of spiral micrometer head, after being in place, then by adjustable screw micrometer head, micrometric screw is made to compress flow cell, after installing, when starting to test, first pass into damping fluid to flow cell and compress effect to check, namely flow cell whether leakage or tension is observed, if snap-in force is too small, liquid is not then had to flow out from liquid outlet, and leakage around flow cell can be observed, need adjustable screw micrometer head, observe again after increasing pressure, until liquid flows out from liquid outlet, and without leakage around flow cell, then compression degree is described just in time, write down the numerical value of now spiral micrometer head, if snap-in force is excessive, then can make the microchannel distortion of flow cell and fluid is not smooth, now the liquid outlet quantity of liquid outlet is significantly smaller than inlet liquid inlet volume, need adjustable screw micrometer head, observe again after reducing pressure, when the liquid outlet quantity of liquid outlet and inlet liquid inlet volume are consistent substantially, then compression degree are described just in time, write down the numerical value of now spiral micrometer head.
The utility model is used according to above-mentioned control method, through adjustable screw micrometer head several times, find out the maxima and minima of the spiral micrometer head that flow cell can be made normally to work, when re-using this flow cell later, only need carry out adjustable screw micrometer head according to this numerical range, thus improve adjustment efficiency, decrease number of operations, efficiently avoid in prior art and repeatedly adjust bolt damage is caused to flow cell.
Described base, for carrying flow cell, conveniently regulates the working position of flow cell, and preferably, described base activity is installed, and described worktable is provided with the locking piece of locking base.
For the ease of installing and manufacturing, preferably, described worktable is provided with the chute of the described base that is slidably installed, and described locking piece is the clamping screw be arranged on chute.
For the ease of the installation and removal of flow cell, preferably, described stand frame comprises:
Two groups of vertical rods, fix on the table, lay respectively at the both sides of base;
Gland, side is hinged on the top of one group of vertical rod, and opposite side is organized vertical rod with another and is connected by movable securing member, and the construction section of described spiral micrometer head is fixed on the middle part of gland.
Said structure makes gland open, and is convenient to the installation and removal of flow cell.
Preferred further, described movable securing member is movable bolt.
In order to make the microchannel surface uniform force of flow cell, thus flow cell is in place, sealing effectiveness is better, and preferably, the below of described micrometric screw is provided with the pressing plate of uniform pressure.
For the ease of location flow cell, preferably, described base is fixed with at least two backstays.Flow cell is provided with the through hole coordinated with backstay.
Preferred further, described pressing plate is provided with the pilot hole coordinated with each backstay.
In order to make flow cell uniform force, pressing plate coordinates the contraposition realized with flow cell by backstay, the centre position covering flow cell working surface can be realized, micrometric screw is now only had to aim at the center of pressing plate, guarantee flow cell uniform force, preferably, described worktable is provided with two tracks be arranged symmetrically with, and the bottom of each group vertical rod is slidably mounted in corresponding track;
Described gland is provided with the slideway of vertical described track, and the construction section of described spiral micrometer head is slidably mounted in this slideway.
Preferably, the end face center of described pressing plate is provided with the registration holes of taper, and the end of described micrometric screw is the taper coordinated with this registration holes.
Come the center of adjustable screw micrometer head to pressing plate by traversing carriage frame and spiral micrometer head, and coordinated with micrometric screw by the registration holes of taper, improve the accuracy of contraposition, ensure flow cell working surface uniform stressed.
The beneficial effects of the utility model:
The device that is fixed and clamped for the miniature flow cell of PDMS of the present utility model, owing to adopting spiral micrometer head as the regulating device of the miniature flow cell of PDMS and base snap-in force, therefore can be carried out the size of controlled pressure by the scale on spiral micrometer head when fixing flow cell, rapid adjustment is to suitable position, thus minimizing number of operations, improve operating efficiency, avoid the infringement repeatedly adjusting and flow cell is caused simultaneously.
Accompanying drawing explanation
Fig. 1 is the perspective view of the present embodiment 1.
Fig. 2 is the perspective view of the present embodiment 1 when using.
Fig. 3 is the perspective view of the miniature flow cell of PDMS.
Fig. 4 is the structural representation of the spiral micrometer head of the present embodiment 1.
Fig. 5 is the perspective view of the present embodiment 2.
Embodiment
Embodiment 1
As shown in Fig. 1,2 and 4, the device that is fixed and clamped for the miniature flow cell of PDMS of the present embodiment comprises: worktable 1, be arranged on worktable 1 for carrying the base 2 of the miniature flow cell of PDMS, to be arranged on this worktable and across the stand frame 3 of base 2, the top vertical of stand frame 3 is provided with spiral micrometer head 4, the micrometric screw 41 of spiral micrometer head 4 is as depression bar, and its end passes the top of stand frame 3 towards base 2.
Worktable 1 is provided with the chute 11 of the base 2 that is slidably installed, and chute 11 is provided with the clamping screw 12 of locking base 2.
Stand frame 3 comprises: two groups of vertical rods 31, are fixed on worktable 1, lay respectively at the both sides of base 2; Gland 32, side is hinged on the top of one group of vertical rod, and opposite side is organized vertical rod with another and is connected by movable bolt 33, and the construction section 42 of spiral micrometer head 4 is fixed on the middle part of gland 32.
The present embodiment also comprises the below that is positioned at micrometric screw 41 pressing plate 5 for uniform pressure, and the both sides of base 2 are fixed with backstay 21 respectively.
Pressing plate 5 is provided with two pilot holes 51 coordinated with each backstay 21.
When the present embodiment uses, open gland 32, the position of adjusting base 2 as required, after adjustment puts in place, clamping screw 12 is tightened, locking base 2, then miniature for PDMS flow cell 6 (hereinafter referred to as flow cell 6) is installed on base, to be coordinated with pilot hole 65 by backstay 21 and locate flow cell 6, then pressing plate 5 is installed, coordinate to come positioning pressuring plate 5 by backstay 21 with pilot hole 51, then gland 32 is closed, and fixed by movable bolt 33, then adjustable screw micrometer head 4 clamping platen 5, uniform spiral micrometer head 4 applied pressure is carried out by arranging pressing plate 5, make pressure can be evenly distributed on flow cell 6, make PDMS module 62 homogeneous deformation of flow cell 6, improve sealing.
After completing preliminary compression, test, pass into damping fluid first to flow cell 6 and compress effect to check, namely flow cell whether leakage or tension is observed, if snap-in force is too small, then do not have liquid to flow out from liquid outlet 64, and the leakage of flow cell 6 surrounding can be observed, need adjustable screw micrometer head 4, observe again, until liquid flows out from liquid outlet 64, and without leakage around flow cell after increasing pressure, then compression degree is described just in time, writes down the numerical value of now spiral micrometer head; If snap-in force is excessive, then can make the microchannel distortion of flow cell 6 and fluid is not smooth, now the liquid outlet quantity of liquid outlet is significantly smaller than inlet liquid inlet volume, need adjustable screw micrometer head 4, observe again after reducing pressure, when the liquid outlet quantity of liquid outlet 64 and inlet liquid inlet volume are consistent substantially, then compression degree are described just in time, write down the numerical value of now spiral micrometer head 4.
The present embodiment is used according to above-mentioned control method, through adjustable screw micrometer head 4 several times, find out the maxima and minima of the spiral micrometer head 4 that flow cell can be made normally to work, when re-using this flow cell 6 later, only need carry out adjustable screw micrometer head according to this numerical range, thus improve adjustment efficiency, decrease number of operations, efficiently avoid in prior art and repeatedly adjust bolt damage is caused to flow cell.
Embodiment 2
As shown in Figure 5, except the mounting means of stand frame and spiral micrometer head in the present embodiment, also have the fit system of pressing plate and micrometric screw different from embodiment 1 beyond, all the other structures are all identical with embodiment 1.
Worktable 1 is provided with two tracks be arranged symmetrically with 7, and the bottom of each group vertical rod 31 is slidably mounted in corresponding track 7;
Gland 32 is provided with the slideway 8 of vertical track 7, and the construction section 42 of spiral micrometer head 4 is slidably mounted in this slideway 8.
The end face center of pressing plate 5 is provided with the registration holes 52 of taper, and the end of micrometric screw 41 is the taper coordinated with registration holes 52.
Before compression, the center of adjustable screw micrometer head 4 to pressing plate is come by traversing carriage frame 3 and spiral micrometer head 4, in compaction process, coordinated with micrometric screw 41 by the registration holes 52 of taper again, adjustable screw micrometer head is regulated put in place, improve the accuracy of contraposition, ensure flow cell working surface uniform stressed.
Claims (8)
1. the device that is fixed and clamped for the miniature flow cell of PDMS, comprise worktable, and install on the table for carrying the base of the miniature flow cell of PDMS, it is characterized in that, also comprise and to be arranged on this worktable and across the stand frame of base, the top vertical of described stand frame is provided with spiral micrometer head, and the micrometric screw of described spiral micrometer head is as depression bar, and its end passes the top of stand frame towards base.
2. as claimed in claim 1 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described base activity is installed, and described worktable is provided with the locking piece of locking base.
3., as claimed in claim 2 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described worktable is provided with the chute of the described base that is slidably installed, and described locking piece is the clamping screw be arranged on chute.
4., as claimed in claim 1 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described stand frame comprises:
Two groups of vertical rods, fix on the table, lay respectively at the both sides of base;
Gland, side is hinged on the top of one group of vertical rod, and opposite side is organized vertical rod with another and is connected by movable securing member, and the construction section of described spiral micrometer head is fixed on the middle part of gland.
5., as claimed in claim 4 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described movable securing member is movable bolt.
6., as claimed in claim 1 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, the below of described micrometric screw is provided with the pressing plate of uniform pressure.
7., as claimed in claim 6 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described base is fixed with at least two backstays.
8., as claimed in claim 7 for the device that is fixed and clamped of the miniature flow cell of PDMS, it is characterized in that, described pressing plate is provided with the pilot hole coordinated with each backstay.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520241382.7U CN204575619U (en) | 2015-04-20 | 2015-04-20 | A kind of device that is fixed and clamped for the miniature flow cell of PDMS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520241382.7U CN204575619U (en) | 2015-04-20 | 2015-04-20 | A kind of device that is fixed and clamped for the miniature flow cell of PDMS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204575619U true CN204575619U (en) | 2015-08-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520241382.7U Withdrawn - After Issue CN204575619U (en) | 2015-04-20 | 2015-04-20 | A kind of device that is fixed and clamped for the miniature flow cell of PDMS |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204575619U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104777274A (en) * | 2015-04-20 | 2015-07-15 | 浙江大学 | Fixing hold-down device for PDMS micro flow cell |
-
2015
- 2015-04-20 CN CN201520241382.7U patent/CN204575619U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104777274A (en) * | 2015-04-20 | 2015-07-15 | 浙江大学 | Fixing hold-down device for PDMS micro flow cell |
| CN104777274B (en) * | 2015-04-20 | 2017-04-19 | 浙江大学 | Fixing hold-down device for PDMS micro flow cell |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20150819 Effective date of abandoning: 20170419 |