CN204008471U - A kind of quantitative testing device of test strips - Google Patents

A kind of quantitative testing device of test strips Download PDF

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Publication number
CN204008471U
CN204008471U CN201420476406.2U CN201420476406U CN204008471U CN 204008471 U CN204008471 U CN 204008471U CN 201420476406 U CN201420476406 U CN 201420476406U CN 204008471 U CN204008471 U CN 204008471U
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CN
China
Prior art keywords
convex lens
spectroscope
test strips
optical detection
optical filter
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Expired - Fee Related
Application number
CN201420476406.2U
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Chinese (zh)
Inventor
蒋凯
杨森
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SUZHOU BAIHUI HUAYE PRECISION APPARATUS Co Ltd
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SUZHOU BAIHUI HUAYE PRECISION APPARATUS Co Ltd
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Abstract

The utility model discloses a kind of quantitative testing device of test strips, comprise: base (1), slide unit (2), drive motor (3) and optical detection apparatus (4), arrange guide rail (11), test strips deck (12), microswitch (13) on base (1); Optical detection apparatus (4) comprises testing circuit module (41), optical detection channel module (42) is thereunder set and is connected to the banking stop (43) of testing circuit module (41) one sides; Optical detection channel module (42) comprises the light emitting diode (421), photodiode (422), the first optical filter (423), the second optical filter (424), the first convex lens (425), the second convex lens (426), the 3rd convex lens (427) and the spectroscope (428) that in it, arrange.Described device has improved the accuracy of detection of fluorescence immune chromatography test paper bar greatly.

Description

A kind of quantitative testing device of test strips
Technical field
The utility model relates to the quantitative testing device in optical detection field, particularly a kind of test strips.
Background technology
Immunochromatography Fast Detection Technique is to be based upon technology on chromatographic technique and Ag-Ab specific immune response basis, fluorescence immune chromatography test paper bar is with the fluorchrome thing that serves as a mark, can be widely used in situ quantitation and detect, be the important directions of following instant detection technique development.
The detailed process that fluorescence immune chromatography test paper bar detects is, detection line in test strips (T) and nature controlling line (C) region are carried out fluorchrome dyeing and are processed, test strips is put into detection sample, in the time detecting the detection subject matter that contains energy and fluorchrome combination in sample, the fluorescence of varying strength will be sent in T line and C line region.Immuno-chromatographic test paper strip quantitative detecting analysis instrument, by scanning test strips, is launched exciting light in scanning process, receives specific wavelength emitting fluorescence, obtains the fluorescence intensity of test strips CT line, thereby analyzes the information such as concentration of measuring subject matter.
In immuno-chromatographic test paper strip quantitative detecting analysis, the structure of core is the design of optical detection passage.Excitation source adopts light emitting diode more at present, light emitting diode is neither pointolite, also non-parallel light source, can not meet the requirement that high precision detects, therefore in high precision detects, need badly to suitable pointolite or to source of parallel light and carry out focus detection, improve the design of optical detection passage, improve accuracy of detection.
Utility model content
For above-mentioned technical matters, the utility model discloses a kind of quantitative testing device of test strips, comprising: base 1, guide rail 11 is set on it, and on described guide rail 11, test strips deck 12 is set, for fixing test strips; Microswitch 13 is installed in the outside, one end of described guide rail 11; Slide unit 2, it is connected on described guide rail 11; Drive motor 3, it is connected to one end of described slide unit 2; Optical detection apparatus 4, it is arranged on described slide unit 2, is driven slide unit 2 and is driven described optical detection apparatus 4 to do straight line back and forth movement by described drive motor 3, carries out the scanning of test strips; Described optical detection apparatus 4 comprises testing circuit module 41 and optical detection channel module 42 is thereunder set and is connected to the banking stop 43 of described testing circuit module 41 1 sides, when optical detection apparatus 4 moves to one end of described guide rail 11, described banking stop 43 touches microswitch 13, and produces position signalling and feed back to testing circuit module 41; Described optical detection channel module 42 comprises the light emitting diode 421, photodiode 422, the first optical filter 423, the second optical filter 424, the first convex lens 425, the second convex lens 426, the 3rd convex lens 427 and the spectroscope 428 that in it, arrange.
Preferably, the first optical filter 423 that the divergent beams that described light emitting diode 421 sends arrange by its dead ahead, right side, after the convergence of the first convex lens 425 that the light beam after transmission arranges through the dead ahead, right side of described the first optical filter 423 again, be irradiated on the spectroscope 428 of described the first convex lens 425 dead aheads, right side settings, described spectroscope 428 changes beam direction, be irradiated on the second convex lens 426 that arrange under spectroscope 428, and through the convergence of described the second convex lens 426, light beam is focused on the checking matter arranging under the second convex lens 426; And checking matter emitting fluorescence under exciting light irradiates, be irradiated on spectroscope 428 through the convergence of the second convex lens 426, see through the fluorescence of spectroscope 428 through being arranged on the convergence of the 3rd convex lens 427 directly over spectroscope 428, arrive again the second optical filter 424 arranging directly over the 3rd convex lens 427, finally received by the photodiode 422 arranging directly over the second optical filter 424; Described spectroscope 428 is arranged in movable spherical structure, by the rotation of described spherical structure, regulates the direction of described spectroscope 428.
The beneficial effects of the utility model are by the light path design in optical detection channel module, have greatly improved the accuracy of detection of fluorescence immune chromatography test paper bar; And described device can effectively be eliminated stray light, improve the fluorescence precision that arrives photodiode; And testing circuit is closed in testing circuit module, can effectively avoids interference, and by banking stop and microswitch are set, can accurately position signalling be fed back to testing circuit, improved detection efficiency and degree of accuracy.
Brief description of the drawings
Fig. 1 is the perspective view of the quantitative testing device of test strips described in the utility model;
Fig. 2 is the latter half structural representation of the quantitative testing device of test strips described in the utility model;
Fig. 3 is the first half structural representation of the quantitative testing device of test strips described in the utility model;
Fig. 4 is the structure cut-open view of optical detection apparatus described in the utility model;
Fig. 5 is the light path design schematic diagram of the quantitative testing device of test strips described in the utility model.
Embodiment
Below in conjunction with accompanying drawing, the utility model is described in further detail, to make those skilled in the art can implement according to this with reference to instructions word.
As shown in the figure, the utility model discloses a kind of quantitative testing device of test strips, comprising: base 1, guide rail 11 is set on it, and on described guide rail 11, test strips deck 12 is set, for fixing test strips; Microswitch 13 is installed in the outside, one end of described guide rail 11; Slide unit 2, it is connected on described guide rail 11; Drive motor 3, it is connected to one end of described slide unit 2; Optical detection apparatus 4, it is arranged on described slide unit 2, is driven slide unit 2 and is driven described optical detection apparatus 4 to do straight line back and forth movement by described drive motor 3, carries out the scanning of test strips; Described optical detection apparatus 4 comprises testing circuit module 41 and optical detection channel module 42 is thereunder set and is connected to the banking stop 43 of described testing circuit module 41 1 sides, when optical detection apparatus 4 moves to one end of described guide rail 11, described banking stop 43 touches microswitch 13, and produces position signalling and feed back to testing circuit module 41; Described optical detection channel module 42 comprises the light emitting diode 421, photodiode 422, the first optical filter 423, the second optical filter 424, the first convex lens 425, the second convex lens 426, the 3rd convex lens 427 and the spectroscope 428 that in it, arrange.
The light path design of whole optical detection passage is as follows: the first optical filter 423 that the divergent beams that light emitting diode 421 sends arrange by its dead ahead, right side, the light that the most of wavelength of transmission is 365nm, after the convergence of the first convex lens 425 that the light beam after transmission arranges through the dead ahead, right side of described the first optical filter 423 again, be irradiated on the semi-transparent semi-reflecting spectroscope 428 of described the first convex lens 425 dead aheads, right side settings, reflect the light that most of wavelength is 365nm, and change beam direction, be irradiated on the second convex lens 426 that arrange under spectroscope 428, and through the convergence of described the second convex lens 426, light beam is focused on the checking matter arranging under the second convex lens 426, utilizing emitted light major part focuses on checking matter, can greatly improve the launching efficiency of fluorescence, and checking matter emitting fluorescence under exciting light irradiates, wavelength is in 610nm left and right, the fluorescence of transmitting has diversity, be irradiated on spectroscope 428 through the convergence of the second convex lens 426, the fluorescence that the most of wavelength of spectroscope 428 transmissions is 610nm, the stray light that reflection wavelength is 365nm simultaneously, fluorescence through spectroscope 428 can produce certain Divergent Phenomenon because of reasons such as refractions, but see through the fluorescence of semi-transparent semi-reflecting spectroscope 428 through being arranged on the convergence of the 3rd convex lens 427 directly over spectroscope 428, greatly improve the detection efficiency of fluorescence, arrive again the second optical filter 424 arranging directly over the 3rd convex lens 427, further eliminate stray light, improve the fluorescence precision that arrives photodiode, final beam is received by the photodiode 422 arranging directly over the second optical filter 424, described spectroscope 428 is arranged in movable spherical structure, by the rotation of described spherical structure, regulates the direction of described spectroscope 428.Whole light path design has greatly improved radiative launching efficiency, meanwhile, has improved the precision of fluoroscopic examination.
Although embodiment of the present utility model is open as above, but it is not restricted to listed utilization in instructions and embodiment, it can be applied to the various fields of the present utility model that are applicable to completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the universal that claim and equivalency range limit, the utility model is not limited to specific details and illustrates here and the legend of describing.

Claims (2)

1. a quantitative testing device for test strips, is characterized in that, comprising:
Base (1), arranges guide rail (11) on it, test strips deck (12) is set on described guide rail (11), for fixing test strips; Microswitch (13) is installed in the outside, one end of described guide rail (11);
Slide unit (2), it is connected on described guide rail (11);
Drive motor (3), it is connected to one end of described slide unit (2);
Optical detection apparatus (4), it is upper that it is arranged on described slide unit (2), driven slide unit (2) and driven described optical detection apparatus (4) to do straight line back and forth movement by described drive motor (3), carries out the scanning of test strips; Described optical detection apparatus (4) comprises testing circuit module (41) and optical detection channel module (42) is thereunder set and is connected to the banking stop (43) of described testing circuit module (41) one sides, when optical detection apparatus (4) moves to one end of described guide rail (11), described banking stop (43) touches microswitch (13), and produces position signalling and feed back to testing circuit module (41); Described optical detection channel module (42) comprises the light emitting diode (421), photodiode (422), the first optical filter (423), the second optical filter (424), the first convex lens (425), the second convex lens (426), the 3rd convex lens (427) and the spectroscope (428) that in it, arrange.
2. the quantitative testing device of test strips according to claim 1, it is characterized in that: the first optical filter (423) that the divergent beams that described light emitting diode (421) sends arrange by its dead ahead, right side, after the convergence of the first convex lens (425) that the light beam after transmission arranges through the dead ahead, right side of described the first optical filter (423) again, be irradiated on the spectroscope (428) of described the first convex lens (425) dead ahead, right side setting, described spectroscope (428) changes beam direction, be irradiated on the second convex lens (426) that arrange under spectroscope (428), and through the convergence of described the second convex lens (426), light beam is focused on the checking matter arranging under the second convex lens (426), and checking matter emitting fluorescence under exciting light irradiates, be irradiated on spectroscope (428) through the convergence of the second convex lens (426), see through the fluorescence of spectroscope (428) through being arranged on the convergence of the 3rd convex lens (427) directly over spectroscope (428), arrive the second optical filter (424) arranging directly over the 3rd convex lens (427), the photodiode (422) finally being arranged directly over the second optical filter (424) receives again, described spectroscope (428) is arranged in movable spherical structure, by the rotation of described spherical structure, regulates the direction of described spectroscope (428).
CN201420476406.2U 2014-08-22 2014-08-22 A kind of quantitative testing device of test strips Expired - Fee Related CN204008471U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104458582A (en) * 2014-12-26 2015-03-25 成都微瑞生物科技有限公司 Optical path structure of chromatography card detector
CN104880450A (en) * 2015-06-18 2015-09-02 苏州和迈精密仪器有限公司 Line focusing detection system for immunofluorescence reagent card
CN105044336A (en) * 2015-07-25 2015-11-11 中山瑞福医疗器械科技有限公司 Multi-channel detecting instrument
CN105259148A (en) * 2015-11-02 2016-01-20 深圳市锦瑞电子有限公司 Fluorescence immunoassay quantitative analyzer
CN106018796A (en) * 2016-07-05 2016-10-12 扬州千代科技有限公司 Immunochromatographic detection system based on single-frequency excitation and double-frequency reception principle and detection method thereof
CN107490674A (en) * 2017-08-02 2017-12-19 南京岚煜生物科技有限公司 A kind of Immunofluorescence test device and detection method
WO2018058525A1 (en) * 2016-09-30 2018-04-05 深圳市检验检疫科学研究院 Fluorescence immunochromatography quantitative analysis instrument and method
CN110044863A (en) * 2019-05-22 2019-07-23 四川朴澜医疗科技有限公司 A kind of semi-automatic immuno-fluorescence specialist system

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104458582A (en) * 2014-12-26 2015-03-25 成都微瑞生物科技有限公司 Optical path structure of chromatography card detector
CN104880450A (en) * 2015-06-18 2015-09-02 苏州和迈精密仪器有限公司 Line focusing detection system for immunofluorescence reagent card
CN105044336A (en) * 2015-07-25 2015-11-11 中山瑞福医疗器械科技有限公司 Multi-channel detecting instrument
CN105259148A (en) * 2015-11-02 2016-01-20 深圳市锦瑞电子有限公司 Fluorescence immunoassay quantitative analyzer
CN106018796A (en) * 2016-07-05 2016-10-12 扬州千代科技有限公司 Immunochromatographic detection system based on single-frequency excitation and double-frequency reception principle and detection method thereof
CN106018796B (en) * 2016-07-05 2017-10-13 扬州千代科技有限公司 A kind of immunochromatography detecting system and its detection method for exciting dual frequency reception principle based on single-frequency
WO2018058525A1 (en) * 2016-09-30 2018-04-05 深圳市检验检疫科学研究院 Fluorescence immunochromatography quantitative analysis instrument and method
CN107490674A (en) * 2017-08-02 2017-12-19 南京岚煜生物科技有限公司 A kind of Immunofluorescence test device and detection method
CN110044863A (en) * 2019-05-22 2019-07-23 四川朴澜医疗科技有限公司 A kind of semi-automatic immuno-fluorescence specialist system
CN110044863B (en) * 2019-05-22 2021-08-10 四川朴澜医疗科技有限公司 Semi-automatic immunofluorescence analysis system

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20141210

Termination date: 20190822

CF01 Termination of patent right due to non-payment of annual fee