CN203953623U - Based on swept light source Gong road optical coherence tomography system - Google Patents
Based on swept light source Gong road optical coherence tomography system Download PDFInfo
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Abstract
The utility model discloses a kind ofly based on swept light source Gong road optical coherent chromatographic imaging (OCT) system, comprise broadband swept light source, three end circulators, probe, interference system and control processing system, probe comprises Green lens and MEMS reflecting mirror; The laser that broadband swept light source is sent enters probe through three end circulators, Green lens in probe pools a part of laser to converge laser, and it after reflecting probe, MEMS reflecting mirror is irradiated on sample sample is carried out to one dimension or two-dimensional scan to obtain sample message, the laser that converges with sample message is got back to three end circulators, forms sample light; Another part laser is direct backspace three end circulators after the end face of Green lens, form reference light; Sample light and reference light enter interference system through three end circulators and form interference signal, and interference signal enters controls processing system processing, forms sample image.This OCT system utilizes the end face of Green lens that reference light is directly provided, and replaces independent sample arm, simple in structure.
Description
Technical field
This utility model belongs to optical coherent chromatographic imaging (Optical Coherence Tomography is called for short OCT) technical field, is specifically related to a kind of based on swept light source Gong road optical coherence tomography system.
Background technology
Optical coherence tomography (OCT, Optical Coherence Tomography) be a kind of emerging technology occurring in recent ten years, it has high-resolution, and can carry out in real time three-dimensional imaging, has become the important video imaging technology in one, field such as medical science, industry, health.OCT mostly is path-splitting type fibre system at present, be that light source is divided into two-way by shunt, one tunnel enters reference arm, one tunnel enters sample arm, the light that this two-way returns finally forms interference information again, and when practical application, sample arm often needs crooked or disposable replacing, in these situations, need so the length of reference arm to regulate, or compensate in software algorithm, or in system, add the hardware such as Polarization Controller to mate, and then the light path that in use produces of compensation sample arm, the change such as dispersion and polarization, to guarantee the quality of image, this has just restricted the real-time application of fiber optic splitter type OCT.
Existing Chinese patent literature CN101091647A discloses a kind of rigid pipe type common-path type endoscopic OCT parallel imaging method and system.In this application patent, adopt Green's rod lens with integral multiple Cycle Length to pass optical device as the interior head of spying upon, use post lens to realize the line focus illumination to internal chamber wall, utilize area array CCD detector to carry out the parallel detecting of spectral domain signal.The front end face of Green's rod lens is placed on post lens back focal plane, the beam shape that integral multiple Cycle Length can guarantee to transfer to rear end face is consistent with incident front end face, therefore can be using rear end face as with reference to face, it and sample have conjugate imaging relation, the two forms the sensing interferometer on Yi Gegong road, and the optical path difference between them is compensated by another common path interference instrument.The combination of line illumination parallel imaging technique and spectral domain Detection Techniques, without scanning the two dimensional image that can obtain fast internal chamber wall.Although this application image quality is not affected by environment and speed is fast, still need extra to make a reflecting surface as with reference to face, and need the complex appts such as automatically controlled platform, increase and realize difficulty.
Utility model content
The purpose of this utility model is to propose a kind ofly without the extra reflecting surface that increases, to provide reference light, and simple in structure, be easy to realize based on swept light source Gong road optical coherence tomography system.
For reaching this object, this utility model by the following technical solutions:
Based on a swept light source Gong road optical coherence tomography system, comprise broadband swept light source, three end circulators, probe, interference system and control processing system, described probe comprises Green lens and MEMS reflecting mirror, the laser that described broadband swept light source is sent enters described probe through described three end circulators, described Green lens in described probe converges a part of laser to form and converges laser, the described laser that converges is irradiated on sample after described MEMS reflecting mirror reflects described probe, described control processing system adds electric control to described MEMS reflecting mirror to be made, through the laser that converges of described MEMS reflecting mirror reflection, sample is carried out to one dimension or two-dimensional scan, to obtain the sample message of one dimension or two dimension, described three end circulators are collected and got back to the laser that converges with sample message through the back scattering of sample different depth by described probe, form sample light, another part laser is directly reflected back described three end circulators after the end face of described Green lens, forms reference light, described sample light and described reference light enter after described interference system is interfered and form interference signal after described three end circulators, and this interference signal is converted to the signal of telecommunication and processes through described control processing system, forms two dimension or the 3-D view of sample.
Wherein, described interference system comprises the first bonder, the first optical fiber, the second optical fiber, the second bonder, described sample light enters described the first bonder and is divided into two bundle sample light after described three end circulators, wherein a branch of sample light enters described the first optical fiber, another bundle sample light enters described the second optical fiber, described reference light enters described the first bonder and is divided into two bundle reference lighies after described three end circulators, wherein a branch of reference light enters described the first optical fiber, another bundle reference light enters described the second optical fiber, through described the first optical fiber, the reference light of described the second optical fiber and sample light enter after described the second bonder, form the dephased two-way interference signal of tool.
Wherein, described the first bonder is one-to-two bonder, and described the second bonder is two minutes two bonders, and described the first optical fiber and the second optical fiber have respectively different length.
Wherein, described control processing system comprises balance detection device, high-speed collection card, computer, control card, described control card output is for driving described MEMS reflecting mirror to make, through the laser that converges of described MEMS reflecting mirror reflection, sample is carried out to the driving signal of one dimension or two-dimensional scan and the synchronizing signal of Sample Scan, described two-way interference signal forms the differentiated signal of telecommunication in road after described balance detection device, this signal of telecommunication enters the data acquisition end of described high-speed collection card, this high-speed collection card is according to the one dimension of described synchronous signal acquisition sample or two-dimensional scan information, and receive the sampled signal that described broadband swept light source is sent, according to described synchronizing signal and described sampled signal, the described signal of telecommunication receiving is carried out to signals collecting conversion, make it convert the discrete interference signal that comprises sample message to, this discrete interference signal carries out Fourier transformation in described computer, to obtain the two dimensional image of sample, described two dimensional image is further reconstructed into 3-D view.
Wherein, described control card is a board or polylith board.
Wherein, described laser is broadband frequency sweep visible ray, near-infrared or infrared light.
Based on a swept light source Gong road optical coherence chromatography imaging method, comprise the following steps:
Steps A: broadband swept light source is sent laser and sampled signal, the synchronizing signal of control card output Sample Scan and for driving MEMS reflecting mirror to make sample to be carried out to the driving signal of one dimension or two-dimensional scan through the laser of described MEMS reflecting mirror reflection;
Step B: the laser in described steps A enters probe through three end circulators, Green lens in probe converges a part of laser to form and converges laser, this converges laser and is irradiated on sample after described MEMS reflecting mirror reflects described probe, simultaneously, described in described drive, MEMS reflecting mirror makes, through the laser that converges of described MEMS reflecting mirror reflection, sample is carried out to one dimension or two-dimensional scan, to obtain the sample message of one dimension or two dimension, three end circulators are collected and got back to the laser that converges with sample message through the back scattering of sample different depth by probe, form sample light, another part laser is directly reflected back three end circulators after the end face of Green lens, forms reference light,
Step C: the reference light in described step B and sample light all enter interference system and forms interference signal; Sample light enters the first bonder and is divided into two bundle sample light after three end circulators, wherein a branch of sample light enters the first optical fiber, another bundle sample light enters the second optical fiber, reference light enters the first bonder and is divided into two bundle reference lighies after three end circulators, wherein a branch of reference light enters the first optical fiber, another bundle reference light enters the second optical fiber, enters after the second bonder the dephased two-way interference signal of formation tool through reference light and the sample light of the first optical fiber, the second optical fiber;
Step D: the two-way interference signal in described step C enters control processing system; Two-way interference signal enters balance detection device, forms the differentiated signal of telecommunication in road after balance detection device;
Step e: described high-speed collection card is according to the scanning information of described synchronous signal acquisition sample, and receive the sampled signal that broadband swept light source is sent, according to synchronizing signal and sampled signal, the signal of telecommunication forming in described step D is carried out to signals collecting conversion, make it convert the discrete interference signal that comprises sample message to;
Step F: import the discrete interference signal collecting in described step e into computer and carry out computing, to obtain the two dimensional image of sample, and show in real time, described two dimensional image is further reconstructed into 3-D view.
The beneficial effects of the utility model are:
Of the present utility model based on swept light source Gong road optical coherence tomography system the intrinsic end face by adopting Green lens as with reference to face, a reflecting surface of the laser sending as reflection broadband swept light source by this end face, after reflection, form reference light, without additional configuration reflecting surface, be used as the plane of reference, thereby fixed structure and control unit that the plane of reference matches have been saved, make the simple in structure of this system, easily realize, and greatly reduce costs.Simultaneously, intrinsic end face by Green lens is as with reference to face, reference light and sample light are propagated in same light path, also made reference light and sample light interfere in omnibus system, and the interference signal after interfering is passed through to balance detection device, realize the autocorrelation signal noise that suppresses common-mode noise and sample itself, and image quality is high, whole system is stable, is not subject to the impact of external environment, during use, without adjusting reference arm, it is more convenient to use.In addition, in interference system, when reference light and the sample interference of light, by the first bonder, the first optical fiber, the second optical fiber and the second bonder, realize full optical fiber optical optical road, without extra reference arm, make this system be easy to integrated, be easy to realize miniaturization.
Accompanying drawing explanation
Fig. 1 is of the present utility model based on swept light source Gong road optical coherence tomography system schematic diagram;
Fig. 2 is of the present utility model based on swept light source Gong road optical coherence chromatography imaging method schematic diagram.
In figure: the swept light source of 1-broadband; 2-tri-end circulators; 3-probe; 4-Green lens; 5-end face; 6-MEMS reflecting mirror; 7-the first bonder; 8-the first optical fiber; 9-the second optical fiber; 10-the second bonder; 11-balance detection device; 12-high-speed collection card; 13-computer; 14-control card.
The specific embodiment
Below in conjunction with accompanying drawing and by the specific embodiment, further illustrate the technical solution of the utility model.
As shown in Figure 1, a kind of based on swept light source Gong road optical coherence tomography system, comprise broadband swept light source 1, three end circulators 2, probe 3, interference system and control processing system, probe 3 comprises Green lens 4 and MEMS reflecting mirror 6, the laser that broadband swept light source 1 is sent enters probe 3 through three end circulators 2, Green lens 4 in probe 3 converges a part of laser to form and converges laser, converge laser is irradiated on sample after MEMS reflecting mirror 6 reflects probe 3, control processing system adds electric control to MEMS reflecting mirror 6 to be made, through the laser that converges of MEMS reflecting mirror 6 reflections, sample is carried out to one dimension or two-dimensional scan, to obtain the sample message of one dimension or two dimension, three end circulators 2 are collected and got back to the laser that converges with sample message through the back scattering of sample different depth by probe 3, form sample light, another part laser is directly reflected back three end circulators 2 after the end face 5 of Green lens 4, forms reference light, sample light and reference light enter after interference system is interfered and form interference signal after three end circulators 2, and this interference signal is converted to the signal of telecommunication and processes through controlling processing system, forms two dimension or the 3-D view of sample.
Wherein, the laser of broadband swept light source 1 output is broadband frequency sweep visible ray (wave-length coverage is between 770～350 nanometers), near-infrared (wavelength is at the electromagnetic wave of 780～3000nm scope) or infrared light.Preferably, in the present embodiment, this laser is the time dependent infrared light of wavelength, and frequency is also changing along with the time, therefore be called swept light source, if centre wavelength is 1310nm, wavelength changes to 1350nm from 1250nm, bandwidth 100nm.Should be based on swept light source Gong road optical coherence tomography system by adopting intrinsic end face 5 conducts of Green lens 4 with reference to face, a reflecting surface of the laser sending as reflection broadband swept light source 1 by this end face 4, after reflection, form reference light, without additional configuration reflecting surface, be used as the plane of reference, thereby saved fixed structure and the control unit matching with the plane of reference, make the simple in structure of this system, easily realize, and greatly reduce costs.
In the present embodiment, interference system is connected with three end circulators 2, and three end circulators 2 are connected with probe 3, controls blood processor and is connected with probe 3, interference system and broadband swept light source 1.Wherein, control processing system MEMS reflecting mirror 6 is added to electric control, particularly, utilize to control between processing system and MEMS reflecting mirror 6 to be electrically connected to, by controlling processing system, send the deflection that the signal of telecommunication is controlled MEMS reflecting mirror 6, thereby realize the one dimension of sample or two-dimensional scan.
Further, interference system comprises the first bonder 7, the first optical fiber 8, the second optical fiber 9, the second bonder 10, sample light enters the first bonder 7 and is divided into two bundle sample light after three end circulators 2, wherein a branch of sample light enters the first optical fiber 8, another bundle sample light enters the second optical fiber 9, reference light enters the first bonder 7 and is divided into two bundle reference lighies after three end circulators 2, wherein a branch of reference light enters the first optical fiber 8, another bundle reference light enters the second optical fiber 9, through the first optical fiber 8, the reference light of the second optical fiber 9 and sample light enter after the second bonder 10, form the dephased two-way interference signal of tool.Further, the first bonder 7 is one-to-two bonder, and the second bonder 10 is two minutes two bonders, and the first optical fiber 8 and the second optical fiber 9 have respectively different length.The effect of the first bonder 7 is to be all divided into two with reference to light and sample light, afterwards wherein a branch of sample light with a branch of reference light wherein through the first optical fiber 8, another bundle sample light and another bundle reference light are through the second optical fiber 9, the reference light and the sample light that from the first optical fiber 8, the second optical fiber 9, enter the second bonder 10 interfere, form two-way interference signal, and interference signal phase difference 180 degree of two-way.
Further, control processing system and comprise balance detection device 11, high-speed collection card 12, computer 13, control card 14, wherein, balance detection device 11 is connected with high-speed collection card 12, and the interference signal sending for receiving interference system, converts interference signal to raw electrical signal, and raw electrical signal is inputted to high-speed collection card, computer 13 is connected with high-speed collection card 12, control card 14, for control card 14 is sent to scan instruction, for receiving the initial data of high-speed collection card 12 outputs, described initial data is carried out to fast fourier transform and obtain two dimension or 3-D view, and show, high-speed collection card 12 is also connected with broadband swept light source 1, particularly, control card 14 outputs are for driving MEMS reflecting mirror 6 to make, through the laser that converges of MEMS reflecting mirror 6 reflections, sample is carried out to the driving signal of one dimension or two-dimensional scan and the synchronizing signal of Sample Scan, two-way interference signal forms the differentiated signal of telecommunication in road after balance detection device 11, this signal of telecommunication enters the data acquisition end of high-speed collection card 12, this high-speed collection card 12 is according to the one dimension of synchronous signal acquisition sample or two-dimensional scan information, and receive the sampled signal that broadband swept light source 1 is sent, according to synchronizing signal and sampled signal, the signal of telecommunication receiving is carried out to signals collecting conversion, make it convert the discrete interference signal that comprises sample message to, this discrete interference signal carries out Fourier transformation in computer 13, to obtain the two dimensional image of sample, and two dimensional image is further reconstructed into 3-D view.
OCT imaging system of the present utility model is passed through end face 5 conducts of Green lens 4 with reference to face, reference light and sample light are propagated in same light path, also make reference light and sample light interfere in omnibus system, and the interference signal after interfering is passed through to balance detection device 11, realize the autocorrelation signal noise that suppresses common-mode noise and sample itself, and image quality is high, whole system is stable, be not subject to the impact of external environment, during use, without adjusting reference arm, it is more convenient to use.In addition, in interference system, when reference light and the sample interference of light, by the first bonder 7, the first optical fiber 8, the second optical fiber 9 and the second bonder 10, realize full optical fiber optical optical road, without extra reference arm, make this system be easy to integrated, be easy to realize miniaturization.
Wherein, control card 14 is a board or polylith board.
As shown in Figure 2, a kind of based on swept light source Gong road optical coherence chromatography imaging method, comprise the following steps:
Steps A: broadband swept light source 1 is sent laser and sampled signal, the synchronizing signal of control card 14 output Sample Scans and for driving MEMS reflecting mirror 6 to make sample to be carried out to the driving signal of one dimension or two-dimensional scan through the laser of MEMS reflecting mirror 6 reflections;
Step B: the laser in steps A enters probe 3 through three end circulators 2, Green lens 4 in probe 3 converges a part of laser to form and converges laser, this converges laser and is irradiated on sample after MEMS reflecting mirror 6 reflects probe 3, simultaneously, drive MEMS reflecting mirror 6 makes, through the laser that converges of MEMS reflecting mirror 6 reflections, sample is carried out to one dimension or two-dimensional scan, to obtain the sample message of one dimension or two dimension, three end circulators 2 are collected and got back to the laser that converges with sample message through the back scattering of sample different depth by probe 3, form sample light, another part laser is directly reflected back three end circulators 2 after the end face 5 of Green lens 4, forms reference light,
Step C: the reference light in step B and sample light all enter interference system and forms interference signal; Sample light enters the first bonder 7 and is divided into two bundle sample light after three end circulators 2, wherein a branch of sample light enters the first optical fiber 8, another bundle sample light enters the second optical fiber 9, reference light enters the first bonder 7 and is divided into two bundle reference lighies after three end circulators 2, wherein a branch of reference light enters the first optical fiber 8, another bundle reference light enters the second optical fiber 9, enters after the second bonder 10 the dephased two-way interference signal of formation tool through reference light and the sample light of the first optical fiber 8, the second optical fiber 9;
Step D: the two-way interference signal in step C enters control processing system; Two-way interference signal enters balance detection device 11, forms the differentiated signal of telecommunication in road after balance detection device 11;
Step e: high-speed collection card 12 is according to the scanning information of synchronous signal acquisition sample, and receive the sampled signal that broadband swept light source 1 is sent, according to synchronizing signal and sampled signal, the signal of telecommunication forming in step D is carried out to signals collecting conversion, make it convert the discrete interference signal that comprises sample message to;
Step F: import the discrete interference signal collecting in described step e into computer and carry out computing, to obtain the two dimensional image of sample, and show in real time, described two dimensional image is further reconstructed into 3-D view.
Balance detection device 11 is a kind of electrooptical devices, containing two photodetectors that parameter is consistent, can do calculus of differences output, obtains the signal of telecommunication containing sample message.In the signal of telecommunication entry altitude capture card 12 of balance detection device 11 outputs, the general sample frequency of high-speed collection card 12 is more than 100M, simultaneously, high-speed collection card 12 starts to gather the data of the signal of telecommunication according to synchronizing signal, now, it is capable and M column data by the N that collects each width 2-D data, and according to the triggering of sampled signal, gather the data message of every bit, after image data signal, high-speed collection card 12 can be transferred to computer 13 together by the some width N*M data (discrete interference signal) that gather, and also can gather a width and transmit a width; Computer 13 receives after the data message being gathered by high-speed collection card 12, the data message of each width is carried out to the fast Fourier transform FFT computing of the capable * M row of N, can obtain the depth structure figure of sample.In addition, due to collection, processing and the display speed of OCT view data reach 30 frames per second more than, so can realize real-time demonstration.
What this utility model was mainly protected is that laser passes through while popping one's head in, a part of laser that an end face of the Green lens of utilization probe sends swept light source directly reflects to form reference light, and another part laser carries out Sample Scan through the transmitting of MEMS reflecting mirror, this sample arm that has replaced needing in prior art providing separately extra provides the form of reference light, whole system structure is simplified greatly, and improve follow-up interference quality, to improve follow-up computer generated image quality, do not relate to the improvement to subsequent calculations machine processing procedure, certainly, in a kind of swept light source OCT Real-time image display method that the process of processing for the data of passing through 13 pairs of receptions of computer of mentioning in this utility model can be 201210337928.X with reference to the application number of Wuxi Wei Ao Science and Technology Ltd. and system thereof, disclosed computer processing procedure is realized.
Know-why of the present utility model has below been described in conjunction with specific embodiments.These are described is in order to explain principle of the present utility model, and can not be interpreted as by any way the restriction to this utility model protection domain.Explanation based on herein, those skilled in the art does not need to pay performing creative labour can associate other specific embodiment of the present utility model, within these modes all will fall into protection domain of the present utility model.
Claims (6)
1. one kind based on swept light source Gong road optical coherence tomography system, it is characterized in that: comprise broadband swept light source (1), three end circulators (2), probe (3), interference system and control processing system, described probe (3) comprises Green lens (4) and MEMS reflecting mirror (6), the laser that described broadband swept light source (1) is sent enters described probe (3) through described three end circulators (2), described Green lens (4) in described probe (3) converges a part of laser to form and converges laser, the described laser that converges is irradiated on sample after described MEMS reflecting mirror (6) reflects described probe (3), described control processing system adds electric control to described MEMS reflecting mirror (6) to be made, through converging laser described in described MEMS reflecting mirror (6) reflection, sample is carried out to one dimension or two-dimensional scan, to obtain the sample message of one dimension or two dimension, described three end circulators (2) are collected and got back to the laser that converges with sample message by described probe (3) after the back scattering of sample different depth, form sample light, another part laser is directly reflected back described three end circulators (2) after the end face (5) of described Green lens (4), forms reference light, described sample light and described reference light enter after described interference system is interfered and form interference signal after described three end circulators (2), and this interference signal is converted to the signal of telecommunication and processes through described control processing system, forms two dimension or the 3-D view of sample.
2. according to claim 1 a kind of based on swept light source Gong road optical coherence tomography system, it is characterized in that: described interference system comprises the first bonder (7), the first optical fiber (8), the second optical fiber (9), the second bonder (10), described sample light enters described the first bonder (7) and is divided into two bundle sample light after described three end circulators (2), wherein a branch of sample light enters described the first optical fiber (8), another bundle sample light enters described the second optical fiber (9), described reference light enters described the first bonder (7) and is divided into two bundle reference lighies after described three end circulators (2), wherein a branch of reference light enters described the first optical fiber (8), another bundle reference light enters described the second optical fiber (9), through described the first optical fiber (8), the reference light of described the second optical fiber (9) and sample light enter after described the second bonder (10), form the dephased two-way interference signal of tool.
3. according to claim 2 a kind of based on swept light source Gong road optical coherence tomography system, it is characterized in that: described the first bonder (7) is one-to-two bonder, described the second bonder (10) is two minutes two bonders, and described the first optical fiber (8) has respectively different length with the second optical fiber (9).
4. according to claim 2 a kind of based on swept light source Gong road optical coherence tomography system, it is characterized in that: described control processing system comprises balance detection device (11), high-speed collection card (12), computer (13), control card (14), described control card (14) output is used for driving described MEMS reflecting mirror (6) to make, through the laser that converges of described MEMS reflecting mirror (6) reflection, sample is carried out to the driving signal of one dimension or two-dimensional scan and the synchronizing signal of Sample Scan, described two-way interference signal forms the differentiated signal of telecommunication in road after described balance detection device (11), this signal of telecommunication enters the data acquisition end of described high-speed collection card (12), this high-speed collection card (12) is according to the one dimension of described synchronous signal acquisition sample or two-dimensional scan information, and receive the sampled signal that described broadband swept light source (1) is sent, according to described synchronizing signal and described sampled signal, the described signal of telecommunication receiving is carried out to signals collecting conversion, make it convert the discrete interference signal that comprises sample message to, this discrete interference signal carries out Fourier transformation in described computer (13), to obtain the two dimensional image of sample, described two dimensional image is further reconstructed into 3-D view.
5. according to claim 4 a kind of based on swept light source Gong road optical coherence tomography system, it is characterized in that: described control card (14) is a board or polylith board.
6. according to claim 1 a kind of based on swept light source Gong road optical coherence tomography system, it is characterized in that: described laser is broadband frequency sweep visible ray, near-infrared or infrared light.
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